BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0146.p (445 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 328 1e-89 RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 325 2e-88 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 322 8e-88 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 320 4e-87 STM1107 [GEPR] COG0477 Permeases of the major facilitator superf... 300 7e-81 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 299 1e-80 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 293 7e-79 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 288 2e-77 YPO1768 [GEPR] COG0477 Permeases of the major facilitator superf... 284 3e-76 PA2214 [GEPR] COG0477 Permeases of the major facilitator superfa... 260 4e-69 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 328 bits (842), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 185/431 (42%), Positives = 272/431 (63%), Gaps = 10/431 (2%) Query: 1 MSQASISPAASAVATAAVSEDATMKKVMRRLIPFILLCYVVSYLDRINVGFAALTMNKDL 60 MS++S + T E+ +K + L+P ++LCYV++YLDR+NVGFA L M DL Sbjct: 1 MSESSTESLSQP--TQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDL 58 Query: 61 GLTPSQFGLGAGLFFIGYFFFEIPSNLALHRFGARMWISRIMISWGLISMATAFVVGPKS 120 + + +GLGAG+FFIGYFF EIPSNL LHR GAR+WI+RIMI+WG+IS AFV P S Sbjct: 59 QFSDTVYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMS 118 Query: 121 FALARFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLSGALME- 179 F + RFLLG+AEAGF PGI LY + WFP RG+ F+I +P++ IIG+PLSG +M+ Sbjct: 119 FYVMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQY 178 Query: 180 LHGMWGFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWLSADEKQWLENELSTEQNV 239 +G G+ GWQ + +LE +P+VL+G++ ++ L DR A WL+ EK L+ + E Sbjct: 179 FNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENE--- 235 Query: 240 LAARHGN-KLKDAFTNWRVFALAGANFCGIIGSLSIGLWLPQIIREFGLPS-HQVGLVAA 297 AA + + +L+DAF RV+ L FC I G +IG WLP +IR+ G+ +G + A Sbjct: 236 -AAHYAHSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTA 294 Query: 298 VPYLVGAVAMTLWARLANRSERRLFFVAGAIVLAALSLGVSAFLHTPL-LKMLAITVAVA 356 +P AV M + +R A+R R + +A VL A+ + +S + + + M+ +T+ Sbjct: 295 IPSAAAAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAM 354 Query: 357 SILSFQATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGPSVIGFIREATQGFTYPLIF 416 LS FW++P+ FL G AAA G+A I S GNLGGFV P ++G++++ TQ T ++ Sbjct: 355 GALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLI 414 Query: 417 VAGALLLGAVI 427 ++ L +GA + Sbjct: 415 ISTTLFIGAAL 425 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 325 bits (832), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 194/442 (43%), Positives = 273/442 (61%), Gaps = 14/442 (3%) Query: 1 MSQASISPAASAVAT------AAVSEDATMKKVMRRLIPFILLCYVVSYLDRINVGFAAL 54 MS S A AV T AA E A ++K+ R++PF+ Y++SYLDR N+G+AAL Sbjct: 1 MSHTQASAGAPAVGTIAARHPAAPDERAIVRKITWRILPFVFALYIISYLDRANIGYAAL 60 Query: 55 TMNKDLGLTPSQFGLGAGLFFIGYFFFEIPSNLALHRFGARMWISRIMISWGLISMATAF 114 MN++L L+ FG +G+FFIGYF FE+PSNL L+RFGAR WI+RI+++WGL++M +AF Sbjct: 61 QMNQELALSSEAFGFVSGIFFIGYFLFEVPSNLMLNRFGARRWIARILVTWGLVAMGSAF 120 Query: 115 VVGPKSFALARFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLS 174 V RFLLG+AEAGF PGI +Y T WF A F IPV+ ++G+PLS Sbjct: 121 VQSATQLYALRFLLGVAEAGFFPGIIVYLTYWFRARELATTVALFTAAIPVSYVVGAPLS 180 Query: 175 GALMELHGMW-GFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWLSADEKQWLENEL 233 +M+ H W + GW+ +LLLE PAV+ G++C L DRP A+WLS E+ WL EL Sbjct: 181 TWIMD-HVHWLQWSGWRWMLLLEGAPAVIGGLLCYGYLADRPKDARWLSEAERDWLLAEL 239 Query: 234 STEQNVL-AARHGNKLKDAFTNWRVFALAGANFCGIIGSLSIGLWLPQIIREF--GLPSH 290 ++ AA H LK T+ RV LA F GSL IG W+PQII+ F L Sbjct: 240 ERDRKARPAAAHLATLK-VMTHPRVLYLAFIYFVYQCGSLGIGYWMPQIIKGFSSALSHT 298 Query: 291 QVGLVAAVPYLVGAVAMTLWARLAN-RSERRLFFVAGAIVLAALSLGVSAFLHTPLLKML 349 +VGL+A +PY+ M W+R ++ R+ERRL A + +AAL+ + F+ P + M Sbjct: 299 EVGLIAMLPYVFATAVMIWWSRRSDLRAERRL-HSAVPLGVAALAFVGAGFIGHPAVAMA 357 Query: 350 AITVAVASILSFQATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGPSVIGFIREATQG 409 +++++A + +F++ FWA+P+ FLT AA +A+I S+GNLGGFVGP IG+ + Sbjct: 358 MLSLSLAGLYAFKSPFWALPTLFLTRSTAAVSIAVINSVGNLGGFVGPFAIGYFKGQMHS 417 Query: 410 FTYPLIFVAGALLLGAVITLAL 431 T L+F+AG L + V+TL L Sbjct: 418 TTAGLLFLAGLLAVSFVMTLRL 439 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 322 bits (826), Expect = 8e-88, Method: Compositional matrix adjust. Identities = 190/437 (43%), Positives = 280/437 (64%), Gaps = 10/437 (2%) Query: 6 ISPAASAVATAAVS--EDATMKKVMRRLIPFILLCYVVSYLDRINVGFAALTMNKDLGLT 63 + P+A A+ + S E+AT +KV RLIPF+LLCYVV+YLDR+NVGFA L M DL + Sbjct: 8 LGPSAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFS 67 Query: 64 PSQFGLGAGLFFIGYFFFEIPSNLALHRFGARMWISRIMISWGLISMATAFVVGPKSFAL 123 + +GLGAG+FFIGYF FE+PSN+ LHR GARMWI+RIMISWGLIS A FV P F + Sbjct: 68 ETVYGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYV 127 Query: 124 ARFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLSG-ALMELHG 182 RFLLG+AEAGF PGI LY T W+P RG+ T FF+ + ++ +IG P+SG AL G Sbjct: 128 MRFLLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGG 187 Query: 183 MWGFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWLSADEKQWLENELSTEQNVLAA 242 ++G GWQ + L+E +P+V++G+ L L +R + A+WL+ +EK L ++ E+ A Sbjct: 188 VYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEE---AQ 244 Query: 243 RHGNKLKDAFTNWRVFALAGANFCGIIGSLSIGLWLPQIIREFGLPSH-QVGLVAAVPYL 301 + + + RV+ ++ F ++G + WLP +I++ G+ VGL+ A+PY Sbjct: 245 KEDAPIAAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYG 304 Query: 302 VGAVAMTLWARLANRSERRLFFVAGAIVLAALSLGVSAFLHT-PLLKMLAITVAVASILS 360 VAM L AR A+R+ R + +A + A+ L +SA HT L M A+T+ IL+ Sbjct: 305 AAVVAMVLVARSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILT 364 Query: 361 FQATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGPSVIGFIREATQGFTYPLIFVAGA 420 FW++P+ FL G AA G+ALI S+GNL GF+ P +G++++ T+ + +A + Sbjct: 365 TLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAAS 424 Query: 421 LLLGAVITLALGDPSRV 437 ++LGA++TL++ P+R Sbjct: 425 MVLGALLTLSV--PART 439 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 320 bits (821), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 178/429 (41%), Positives = 272/429 (63%), Gaps = 4/429 (0%) Query: 5 SISPAASAVATAAVSEDATMKKVMRRLIPFILLCYVVSYLDRINVGFAALTMNKDLGLTP 64 ++ + +A+ + V E+ T +KV R+IP +++CY+++YLDR+NVGFA L M+++LG + Sbjct: 18 AMKNSNTAITSPEVVENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSE 77 Query: 65 SQFGLGAGLFFIGYFFFEIPSNLALHRFGARMWISRIMISWGLISMATAFVVGPKSFALA 124 + +GLGAGLFFIGYFFFEIPSN+ LH+ GAR+WI+RIMI+WGL+S AFV F + Sbjct: 78 AIYGLGAGLFFIGYFFFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYIL 137 Query: 125 RFLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLSGALME-LHGM 183 RFLLG AEAGF PG+ LY T WFP RG A F G P A I G+PLSG +M+ H Sbjct: 138 RFLLGAAEAGFYPGVILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDT 197 Query: 184 WGFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWLSADEKQWLENELSTEQNVLAAR 243 G++GWQ + +LEA+PAV+LGV+ L L + AKWL+ +EK + ++ + AA Sbjct: 198 AGWQGWQWMFVLEAIPAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAAS 257 Query: 244 HGNKLKDAFTNWRVFALAGANFCGIIGSLSIGLWLPQIIREFGLPSH-QVGLVAAVPYLV 302 H L N ++ + FC ++G + LW+P +IR G+ S+ +GL+ A+P++ Sbjct: 258 H--SLMSLVKNPMLWVMMLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFIC 315 Query: 303 GAVAMTLWARLANRSERRLFFVAGAIVLAALSLGVSAFLHTPLLKMLAITVAVASILSFQ 362 +AM +++R A+ R + + +L A+ V+A + ++ +++A A +L+ Sbjct: 316 AIIAMVIFSRSADHYRERRWHLVVPALLGAVGFVVAASATNTTVSIIFLSMAAAGVLACA 375 Query: 363 ATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGPSVIGFIREATQGFTYPLIFVAGALL 422 FW++P+ L+G AAA G+ALI S+ NL GF+ P ++G IR+AT + +AG L+ Sbjct: 376 PLFWSLPTAILSGAAAAAGIALINSVANLAGFISPYMVGIIRDATHSSELGMYVLAGFLI 435 Query: 423 LGAVITLAL 431 LGA I L + Sbjct: 436 LGAAIVLCI 444 >STM1107 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 458 Score = 300 bits (767), Expect = 7e-81, Method: Compositional matrix adjust. Identities = 170/434 (39%), Positives = 253/434 (58%), Gaps = 14/434 (3%) Query: 7 SPAASAVATA-AVSEDATMKKVMRRLIPFILLCYVVSYLDRINVGFAALTMNKDLGLTPS 65 SP + + A + + + K+ RRLI F+ + ++ S+LDRIN+GFA LTM +DLGL+ + Sbjct: 11 SPESVSSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSAT 70 Query: 66 QFGLGAGLFFIGYFFFEIPSNLALHRFGARMWISRIMISWGLISMATAFVVGPKSFALAR 125 FGL LF+ Y F IPSN+ L GAR WI+ IM+ WG+ S AT F VGPKS + R Sbjct: 71 MFGLATTLFYATYVIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFAVGPKSLYVLR 130 Query: 126 FLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLSGALMELHGMWG 185 L+G+ EAGF PGI LY T WFP +R +A A F+I +P +GS +SG ++ L G++ Sbjct: 131 MLVGITEAGFLPGILLYLTYWFPAFFRARANALFMIAMPATTALGSIVSGYILSLDGIFN 190 Query: 186 FKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWLSADEKQWLENELSTEQNVLAARHG 245 GWQ L LLE P+VLLG+M F L D PAKAKWL+A++K+ L+ + +++ L G Sbjct: 191 LHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDSDRLTLVQPEG 250 Query: 246 NKLKDAFTN---WR------VFALAGANFCGIIGSLS-IGLWLPQIIREF--GLPSHQVG 293 +A WR V A FC + +LS I +W PQI++ F G + +G Sbjct: 251 AISHNAMQQRSLWREVFTPIVLMYTLAYFC-LTNTLSAISIWTPQILKSFNEGSSNITIG 309 Query: 294 LVAAVPYLVGAVAMTLWARLANRSERRLFFVAGAIVLAALSLGVSAFLHTPLLKMLAITV 353 L+AA+P + + M W+R +++ + R A + AA +++ L+++L I + Sbjct: 310 LLAAIPQICTILGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIVM 369 Query: 354 AVASILSFQATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGPSVIGFIREATQGFTYP 413 A S A FW P ++ RA A G+A+I + GN+G + P +IG++++ T F Sbjct: 370 ASTGSFSAMAIFWTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLKDITGSFNSG 429 Query: 414 LIFVAGALLLGAVI 427 L FVA L++GA I Sbjct: 430 LWFVASLLVVGAAI 443 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 299 bits (765), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 163/412 (39%), Positives = 248/412 (60%), Gaps = 1/412 (0%) Query: 18 VSEDATMKKVMRRLIPFILLCYVVSYLDRINVGFAALTMNKDLGLTPSQFGLGAGLFFIG 77 VSE A + K+ RL+PF+ L Y+++Y+DR NV +A L M L L+ +GLGA LFFIG Sbjct: 64 VSEKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIG 123 Query: 78 YFFFEIPSNLALHRFGARMWISRIMISWGLISMATAFVVGPKSFALARFLLGMAEAGFTP 137 YF FE+PSNL L+RFGA W +RI++SWG +++A A+ F + RFLLG+ EAGF P Sbjct: 124 YFLFEVPSNLFLNRFGASKWFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFP 183 Query: 138 GIYLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLSGALMELHGMWGFKGWQVLLLLEA 197 G+ T WFP +RG+ F+I +AN +G+PL G L++L G G+ GW+ + L Sbjct: 184 GVLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGMLLDLDGFLGYAGWEWVFLATG 243 Query: 198 LPAVLLGVMCLFLLPDRPAKAKWLSADEKQWLENELSTEQNVLAARHGNKLKDAFTNWRV 257 +PAV+ G++ F L D P KAK+L+ DEK WL+N L+ E+N H A N RV Sbjct: 244 IPAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLA-EENKGMEEHAEDGFKALVNPRV 302 Query: 258 FALAGANFCGIIGSLSIGLWLPQIIREFGLPSHQVGLVAAVPYLVGAVAMTLWARLANRS 317 +A + + + WLP I++ FG+ + G + +P+++ A+A+ + A+++ Sbjct: 303 LFMALCYVGFPLAAYGLSYWLPTIVKSFGVSNTTNGFINIIPWIIVAIALFVVPSAADKA 362 Query: 318 ERRLFFVAGAIVLAALSLGVSAFLHTPLLKMLAITVAVASILSFQATFWAIPSGFLTGRA 377 + + ++ G + A L +SA L P+L+ + VA A I + Q FW++P FL G Sbjct: 363 KNKTPYIVGPAFVGAFCLLMSALLSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAG 422 Query: 378 AAGGLALIVSIGNLGGFVGPSVIGFIREATQGFTYPLIFVAGALLLGAVITL 429 AA G+A I S+GNLGGFV +V+ +I++ T P+ F+A L L V+ + Sbjct: 423 AAAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFLAFCLALAGVLVI 474 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 293 bits (749), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 164/423 (38%), Positives = 246/423 (58%), Gaps = 2/423 (0%) Query: 20 EDATMKKVMRRLIPFILLCYVVSYLDRINVGFAALTMNKDLGLTPSQFGLGAGLFFIGYF 79 E AT+ +V RRL+P L Y+++Y+DR NV +A L M LGL+ + +GLGA LFFIGYF Sbjct: 9 ERATVGRVTRRLMPLFCLMYLIAYIDRQNVSYAKLDMVSALGLSEAAYGLGASLFFIGYF 68 Query: 80 FFEIPSNLALHRFGARMWISRIMISWGLISMATAFVVGPKSFALARFLLGMAEAGFTPGI 139 FE P+NL L R GAR+W +RIM SWGL+++A F F + RFLLG+AEAGF PG+ Sbjct: 69 LFEAPANLILARVGARVWFARIMFSWGLVTLALGFTQNAAMFYVLRFLLGVAEAGFFPGV 128 Query: 140 YLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLSGALMELHGMWGFKGWQVLLLLEALP 199 T W+P A R + F+I AN +G+ + G L+ + G G GWQ + L+ P Sbjct: 129 LYVLTLWYPQAHRARMVGLFMIASAFANAVGAAIGGLLLGMDGFLGLAGWQWVFLVTGAP 188 Query: 200 AVLLGVMCLFLLPDRPAKAKWLSADEKQWLENELSTEQNVLAARHGNKLKDAFTNWRVFA 259 AVLL L+ LP P+ A+WL EK WL + L+ E+ H K F RV Sbjct: 189 AVLLAPYVLWRLPSGPSDARWLPDVEKSWLASTLAAERGGEVDDHRGAWKAIFDP-RVLM 247 Query: 260 LAGANFCGIIGSLSIGLWLPQIIREFGLPSHQVGLVAAVPYLVGAVAMTLWARLANRSER 319 LAG + + + WLP I++ FG+ + G + +P+L+ AVA+ R A R Sbjct: 248 LAGLYIGMPLSAYGLSYWLPTIVKSFGVSNTVNGFINVIPWLLVAVALWFVPRHAARHGA 307 Query: 320 RLFFVAGAIVLAALSLGVSAFLHTPLLKMLAITVAVASILSFQATFWAIPSGFLTGRAAA 379 + +AG ++LAA++L +S L LK + +A +I + Q FW++P FL+G AA Sbjct: 308 SAWHIAGPVLLAAVALSLSVILPGAALKFTMLCIAAPAIFAAQPVFWSLPPSFLSGPRAA 367 Query: 380 GGLALIVSIGNLGGFVGPSVIGFIREATQGFTYPLIFVAGALLLGA-VITLALGDPSRVP 438 G+A I ++GNLGGF+ +++ +R+AT P++ +A LL+ + +I + +G ++ Sbjct: 368 AGIATINAVGNLGGFIAQNLVPVVRDATGSELAPMLALAAVLLVTSLLIFIVMGRLRKMS 427 Query: 439 PTS 441 P + Sbjct: 428 PAT 430 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 288 bits (736), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 167/404 (41%), Positives = 237/404 (58%), Gaps = 9/404 (2%) Query: 9 AASAVATAAVSED---ATMKKVMRRLIPFILLCYVVSYLDRINVGFAALTMNKDLGLTPS 65 AA+A+ A S + + V RR++PF+ CY+ +YLDRIN+GFA L M DL L+ + Sbjct: 2 AANAIPAQAHSGERSTSVYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDA 61 Query: 66 QFGLGAGLFFIGYFFFEIPSNLALHRFGARMWISRIMISWGLISMATAFVVGPKSFALAR 125 +GLGAG+FF GY FE+PSNL L + GAR +SRI+I WG++S + FV +F R Sbjct: 62 AYGLGAGIFFFGYMLFEVPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALR 121 Query: 126 FLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLSGALM-ELHGMW 184 FLLG+ EAGF PG+ Y TQW+PG +A A L P+ +IG P S +M G Sbjct: 122 FLLGVFEAGFAPGMIYYLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAG 181 Query: 185 GFKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWLSADEKQWLENELSTEQNVLAARH 244 G GWQ + L E +P++LLG+ L D+PA A+WL+ +K + +++ A Sbjct: 182 GLAGWQWMFLAEGIPSILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIARA----APGQ 237 Query: 245 GNKLKDAFTNWRVFALAGANFCGIIGSLSIGLWLPQIIREFGLPS-HQVGLVAAVPYLVG 303 + A T +++ LA A FC I G ++G WLP I++ GL Q+GL +A+P L Sbjct: 238 ASSFGKALTEPKLYVLAAAYFCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAM 297 Query: 304 AVAMTLWARLANRSERRLFFVAGAIVLAALSLGVSAFLHTPLLKMLAITVAVASILSFQA 363 VAM R ++R R A VL A L +A+ + +++IT+A A+I + + Sbjct: 298 IVAMYALGRRSDRRGERHLHSAITAVLGAGLLAWAAYATSFPAALISITLASAAIFASYS 357 Query: 364 TFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGPSVIGFIREAT 407 FWAIP L G AAAGG+ALI SIG GGF P++IG+ +EAT Sbjct: 358 VFWAIPQQHLKGTAAAGGIALINSIGLFGGFFSPTLIGWTKEAT 401 >YPO1768 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 284 bits (727), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 169/445 (37%), Positives = 255/445 (57%), Gaps = 11/445 (2%) Query: 6 ISPAASAVATAAVSEDATMKKVMRRLIPFILLCYVVSYLDRINVGFAALTMNKDLGLTPS 65 ++P + + + + + K+ RRLIPF+ L +V ++LDRIN+GFA LTM KDLGL+ + Sbjct: 11 VTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSAT 70 Query: 66 QFGLGAGLFFIGYFFFEIPSNLALHRFGARMWISRIMISWGLISMATAFVVGPKSFALAR 125 FGL LF++ Y F IPSN+ L GAR WI+ IM+ WG+ S AT F VGP S L R Sbjct: 71 TFGLATTLFYVTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLR 130 Query: 126 FLLGMAEAGFTPGIYLYFTQWFPGAWRGKATAFFLIGIPVANIIGSPLSGALMELHGMWG 185 ++G+ EAGF PGI +Y T WFP +R +A A F++ +PV +GS +SG ++ L G Sbjct: 131 MIVGITEAGFLPGILVYLTYWFPAHFRARANALFMVAMPVTMALGSLVSGYILALDGFLN 190 Query: 186 FKGWQVLLLLEALPAVLLGVMCLFLLPDRPAKAKWLSADEKQWLENELSTEQNVLAARHG 245 +GWQ L LLE P+VLLG + F L D P KA+WL+ ++KQ L+ L +++ LA + Sbjct: 191 MRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLESDRLQLAKQAD 250 Query: 246 NKLKDAFTNWR------VFALAGANFCGIIGSLS-IGLWLPQIIREFGLPSHQ--VGLVA 296 WR V A FC + +LS + +W PQI++ F S +GL+A Sbjct: 251 YGALPQSAMWREIFTPVVLMYTLAYFC-LTNTLSAVNIWTPQILQSFNQSSSNITIGLLA 309 Query: 297 AVPYLVGAVAMTLWARLANRSERRLFFVAGAIVLAALSLGVSAFLHTPLLKMLAITVAVA 356 A+P + M W+R ++R + R + AA +++ ++++L I +A Sbjct: 310 AIPQVCTIAGMIWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGIIMAST 369 Query: 357 SILSFQATFWAIPSGFLTGRAAAGGLALIVSIGNLGGFVGPSVIGFIREATQGFTYPLIF 416 + A FW P ++ RA A G+A+I + GN+G V P +IG++++ T F L F Sbjct: 370 GSFTAMAIFWTTPDQSISLRARAVGIAVINATGNIGSAVSPVLIGWLKDQTGNFNSGLYF 429 Query: 417 VAGALLLGAVITLALGDPSRVPPTS 441 VAG L++GAVI L + + PP + Sbjct: 430 VAGLLVIGAVIFLMI-PMKKAPPKA 453 >PA2214 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 440 Score = 260 bits (665), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 166/418 (39%), Positives = 235/418 (56%), Gaps = 4/418 (0%) Query: 30 RLIPFILLCYVVSYLDRINVGFAALTMNKDLGLTPSQFGLGAGLFFIGYFFFEIPSNLAL 89 RL+PF++L YV++++DR NVG+A + D GL + F GA +FFIGY FE+PSNL L Sbjct: 21 RLLPFLVLMYVLAFIDRANVGYARAFLQADTGLGDAAFAFGASIFFIGYACFEVPSNLML 80 Query: 90 HRFGARMWISRIMISWGLISMATAFVVGPKSFALARFLLGMAEAGFTPGIYLYFTQWFPG 149 HR GAR+W+ RIM++WGL+S A F +F + RFLLG+AEAGF PGI LY T WFP Sbjct: 81 HRLGARVWLCRIMVTWGLVSAAMMFADDAMTFYVLRFLLGVAEAGFFPGIILYLTYWFPQ 140 Query: 150 AWRGKATAFFLIGIPVANIIGSPLSGALMELHGMWGFKGWQVLLLLEALPAVLLGVMCLF 209 R +A F G+P+A ++G PLSG L+E HG++G WQ L + E L A L+G+ F Sbjct: 141 RSRAQALGLFYFGLPLALVLGGPLSGWLLEFHGIFGLANWQWLFVTEGLLASLVGIAAYF 200 Query: 210 LLPDRPAKAKWLSADEKQWLENELSTEQNVLAARHGNKLKDAFTNWRVFALAGANFCGII 269 L DRP A WLS ++K+ LE EL+ E AR + A + +V F + Sbjct: 201 YLVDRPRDAGWLSDEQKRALEGELAEEDTRKQARGPHGFLSALRSGQVLKFCLVYFTIQM 260 Query: 270 GSLSIGLWLPQIIREF--GLPSHQVGLVAAVPYLVGAVAMTLWARLANRSERRLFFVAGA 327 + +LP I F G VGL+ A+P++ V L R A+RS + Sbjct: 261 SVYGVVFYLPTRIASFLDGQVGLNVGLITAIPWVCALVVTRLVTRQADRSGQHRQLAVAM 320 Query: 328 IVLAALSLGVSAFLHTPLLKMLAITVAVASILSFQATFWAIPSGFLTGRAAAGGLALIVS 387 + +AA + SA L ++A A + +S Q FW +P+G+L+G AAA G+ALI S Sbjct: 321 LGMAAAGIAASALAGNLGLAVIAFCFAASGFVSVQPLFWTLPTGYLSGAAAASGIALINS 380 Query: 388 IGNLGGFVGPSVIGFIREATQGFTYPLIFVAGALLLGAVI--TLALGDPSRVPPTSKE 443 +GNLGGFV P++ + + +A LLGA + L S VP +++ Sbjct: 381 LGNLGGFVAPNLKTLMESQFADPRAGMFALAAVGLLGACLLARLKTSGSSSVPLRARQ 438