BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0078.p (207 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI1312 [S] COG1284 Uncharacterized conserved protein Bme Bruce... 207 1e-53 AGc869 [S] COG1284 Uncharacterized conserved protein Atu Agrobac... 192 3e-49 SMc02240 [S] COG1284 Uncharacterized conserved protein Sme Sinor... 161 9e-40 AGc867 [S] COG1284 Uncharacterized conserved protein Atu Agrobac... 154 1e-37 VC0940 [S] COG1284 Uncharacterized conserved protein Vch Vibrio ... 141 9e-34 BH3878 [S] COG1284 Uncharacterized conserved protein Bha Bacillu... 84 3e-16 CAC1325 [S] COG1284 Uncharacterized conserved protein Cac Clostr... 79 8e-15 lin1422 [S] COG1284 Uncharacterized conserved protein Lin Lister... 71 2e-12 SPy2155 [S] COG1284 Uncharacterized conserved protein Spy Strept... 63 5e-10 SPy2153 [S] COG1284 Uncharacterized conserved protein Spy Strept... 60 5e-09 >BMEI1312 [S] COG1284 Uncharacterized conserved protein Bme Brucella melitensis Length = 217 Score = 207 bits (526), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 98/195 (50%), Positives = 148/195 (75%) Query: 13 RHRSYEDVLALVAGTLFISLGVNMYTQVGLLTGSTAGLAFLAHYLTGLPFGAVFFTINLP 72 RHR YED +A++ GT FI+LG+ +Y+ L+TGSTAG+A L HY TG FG ++F INLP Sbjct: 22 RHRLYEDAIAMLIGTSFIALGITLYSHAMLMTGSTAGIALLIHYATGTGFGLLYFLINLP 81 Query: 73 FYYFAWRRMGKRFMLKTFCAVALVSGFSLMHPYFISYGKLDLFYSAVLGGLLIGVGFVML 132 FYYFA RRMG F ++TF AVAL+SGF+ + P + + ++ ++A++GG L+G+G + L Sbjct: 82 FYYFAVRRMGWAFTIRTFAAVALLSGFTRLMPLSVDFTSINPLFAALMGGTLMGMGVLAL 141 Query: 133 FRHGASLGGINVVTLFLQDRYGLRAGKLQMGVDVVIVLCSLWVVAPKVLLASILGAVTAN 192 FRH + +GG+N++ L+LQD YG+RAG Q+G+DV+I+L SL+ + + ++ S++GAV N Sbjct: 142 FRHRSGVGGVNILALYLQDAYGIRAGWFQLGLDVLIMLASLFFIPWENMVLSLVGAVAMN 201 Query: 193 LIIALNHRAGRYMGM 207 +IIA+NH+ GRY+G+ Sbjct: 202 VIIAINHKPGRYIGI 216 >AGc869 [S] COG1284 Uncharacterized conserved protein Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 237 Score = 192 bits (489), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 97/199 (48%), Positives = 134/199 (67%) Query: 9 AADVRHRSYEDVLALVAGTLFISLGVNMYTQVGLLTGSTAGLAFLAHYLTGLPFGAVFFT 68 +A RH ED A++AG++ ISLGV +++ GLLTG GLAFLAHY +G FGAVFF Sbjct: 39 SAPDRHSLLEDAQAILAGSMLISLGVTLFSAAGLLTGGVVGLAFLAHYASGFSFGAVFFL 98 Query: 69 INLPFYYFAWRRMGKRFMLKTFCAVALVSGFSLMHPYFISYGKLDLFYSAVLGGLLIGVG 128 NLPFYY A+RR+G F +KTFCA+A + S P F ++ ++ +A+ GGL + G Sbjct: 99 ANLPFYYLAFRRLGLAFTVKTFCAIATTALLSEYMPGFFAFESINPIAAALFGGLTVAAG 158 Query: 129 FVMLFRHGASLGGINVVTLFLQDRYGLRAGKLQMGVDVVIVLCSLWVVAPKVLLASILGA 188 + LFRH SLGG ++ L+LQDR+G RAG +Q+ D +++ CS +V P V+L SILGA Sbjct: 159 MLALFRHRTSLGGFGILALYLQDRFGWRAGLVQLAFDGMVLGCSFFVATPFVILCSILGA 218 Query: 189 VTANLIIALNHRAGRYMGM 207 + NL +A+NHR RY+ M Sbjct: 219 LVMNLTLAVNHRNDRYIAM 237 >SMc02240 [S] COG1284 Uncharacterized conserved protein Sme Sinorhizobium meliloti Length = 211 Score = 161 bits (408), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 89/198 (44%), Positives = 136/198 (68%) Query: 10 ADVRHRSYEDVLALVAGTLFISLGVNMYTQVGLLTGSTAGLAFLAHYLTGLPFGAVFFTI 69 + RH EDV + +G+L +LG+ GLLTGSTAG+AFL HY TG+ FG FF + Sbjct: 14 SPTRHTPVEDVQGVFSGSLVAALGLYFLASAGLLTGSTAGVAFLLHYATGVNFGLTFFLL 73 Query: 70 NLPFYYFAWRRMGKRFMLKTFCAVALVSGFSLMHPYFISYGKLDLFYSAVLGGLLIGVGF 129 NLPF+Y + +R+G F LKTF A+AL S + M G++ ++A++GGLL+G G Sbjct: 74 NLPFFYLSLKRLGPAFTLKTFIAIALTSFLTDMQSRLFEIGQIHPGWAALIGGLLLGYGL 133 Query: 130 VMLFRHGASLGGINVVTLFLQDRYGLRAGKLQMGVDVVIVLCSLWVVAPKVLLASILGAV 189 + L+RH ASLGG+ ++ ++LQ+R+G+RAG +Q+ +D+V++ + +V P V++ S+LGAV Sbjct: 134 LALYRHRASLGGVGILGIYLQERFGIRAGLVQLAIDLVVLAAAFFVTTPTVVIWSVLGAV 193 Query: 190 TANLIIALNHRAGRYMGM 207 NL +A+NHRA RY+ + Sbjct: 194 VLNLFVAINHRADRYIAL 211 >AGc867 [S] COG1284 Uncharacterized conserved protein Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 230 Score = 154 bits (388), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 86/198 (43%), Positives = 133/198 (67%) Query: 8 AAADVRHRSYEDVLALVAGTLFISLGVNMYTQVGLLTGSTAGLAFLAHYLTGLPFGAVFF 67 ++ RH EDV +V G + +LG + +VGLLTG TAG+AFL HY G+ FG +FF Sbjct: 30 SSDPARHAPVEDVQGIVTGAIVSALGFYLLAKVGLLTGGTAGVAFLLHYAFGISFGLLFF 89 Query: 68 TINLPFYYFAWRRMGKRFMLKTFCAVALVSGFSLMHPYFISYGKLDLFYSAVLGGLLIGV 127 +NLPFYY ++RR+G F KTF A+ LVS + + ++ ++ ++A+LGGLL+G Sbjct: 90 LVNLPFYYLSFRRLGLAFSCKTFIAIGLVSVLTEVEARWMVIDSINPLWAALLGGLLLGY 149 Query: 128 GFVMLFRHGASLGGINVVTLFLQDRYGLRAGKLQMGVDVVIVLCSLWVVAPKVLLASILG 187 G + L+RH ASLGGI ++ +++QDR+G+RAG +Q+ D ++LC+ V+ P + SI+G Sbjct: 150 GLLALYRHRASLGGIGILAIYIQDRFGIRAGLIQLAFDACVMLCAFLVIDPATVAYSIVG 209 Query: 188 AVTANLIIALNHRAGRYM 205 A N+ +A+NHR+ RY+ Sbjct: 210 AFVLNIFLAINHRSDRYI 227 >VC0940 [S] COG1284 Uncharacterized conserved protein Vch Vibrio cholerae Length = 198 Score = 141 bits (356), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 84/192 (43%), Positives = 120/192 (62%) Query: 13 RHRSYEDVLALVAGTLFISLGVNMYTQVGLLTGSTAGLAFLAHYLTGLPFGAVFFTINLP 72 +H ED +A++ GT ++ GV LLTG T GLA L L FG ++F N P Sbjct: 3 KHSHKEDWIAILTGTFLVAQGVYFLQAGQLLTGGTTGLALLMTQFLPLTFGVLYFLSNCP 62 Query: 73 FYYFAWRRMGKRFMLKTFCAVALVSGFSLMHPYFISYGKLDLFYSAVLGGLLIGVGFVML 132 FY AW+R G RF + + ALVS F+ I+ K+++ Y AV GGLL+G+G ++L Sbjct: 63 FYLLAWKRFGARFAFNSAISGALVSIFADHLAMLITLEKVNVVYCAVAGGLLMGLGMLIL 122 Query: 133 FRHGASLGGINVVTLFLQDRYGLRAGKLQMGVDVVIVLCSLWVVAPKVLLASILGAVTAN 192 FRH +SLGG NV+ LF+QDR+G+ GK QM +D +I+L S + V+P + SILGA N Sbjct: 123 FRHRSSLGGFNVLCLFIQDRFGISVGKSQMAIDGLILLASFFFVSPLTIGLSILGAFLLN 182 Query: 193 LIIALNHRAGRY 204 +++A+NH+ RY Sbjct: 183 IVLAMNHKPSRY 194 >BH3878 [S] COG1284 Uncharacterized conserved protein Bha Bacillus halodurans Length = 211 Score = 83.6 bits (205), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 67/170 (39%), Positives = 97/170 (57%), Gaps = 2/170 (1%) Query: 26 GTLFISLGVNMYTQVGLLTGSTAGLAFLAHYLTGLPFGAVFFTINLPFYYFAWRRMGKRF 85 G + S GV + L+TG TAGL+ YL LPF FF +N+PFY F+ RMG F Sbjct: 10 GIVITSCGVILLRHANLVTGGTAGLSLGMTYLFNLPFALTFFLVNVPFYLFSLLRMGWSF 69 Query: 86 MLKTFCAVALVSGFSLMHPYFISYGKLDLFYSAVLGGLLIGVGFVMLFRHGASLGGINVV 145 T +V+L+S + + + S+ + ++ AV GG LIG+G ++F +G+SLGG N++ Sbjct: 70 TRSTIISVSLLSLVTSLDVWLPSF-NVPVWLGAVFGGGLIGLGLSLIFMNGSSLGGANIL 128 Query: 146 TLFLQDRYGLRAGKLQMGVDVVIVLCSLWVVAPKVLLASILG-AVTANLI 194 L+LQ R + GK DV +VL S+ V L SIL AVT+ +I Sbjct: 129 ALYLQKRLAIDPGKTNFLFDVSVVLLSMVSVGVIRGLLSILSIAVTSRII 178 >CAC1325 [S] COG1284 Uncharacterized conserved protein Cac Clostridium acetobutylicum Length = 285 Score = 78.6 bits (192), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 43/147 (29%), Positives = 79/147 (53%), Gaps = 4/147 (2%) Query: 18 EDVLALVAGTLFISLGVNMY-TQVGLLTGSTAGLAFLAHYLTGLPFGAVFFTINLPFYYF 76 +L +V G++ S+G+ ++ ++ G G++ +A++ LP G F +NLPF Sbjct: 13 NKILLMVLGSVIASVGLEIFLIPNNIIDGGITGISIIANHFINLPLGIFIFLLNLPFLIV 72 Query: 77 AWRRMGKRFMLKT-FCAVALVSGFSLMHPYFISYGKLDLFYSAVLGGLLIGVGFVMLFRH 135 ++++GK F T F + L G S++HP I D+ + + GG+++G G ++ R+ Sbjct: 73 GYKQIGKTFAFSTLFSVICLSIGVSVLHP--IPGITHDILLATIFGGIILGAGVGLIIRN 130 Query: 136 GASLGGINVVTLFLQDRYGLRAGKLQM 162 G SL G +V + L R G G++ M Sbjct: 131 GGSLDGTEIVAIILDKRIGFSIGEIVM 157 >lin1422 [S] COG1284 Uncharacterized conserved protein Lin Listeria innocua Length = 308 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 39/135 (28%), Positives = 74/135 (54%), Gaps = 9/135 (6%) Query: 42 LLTGSTAGLAFLAHYLTGLPFGAVFFTINLPFYYFAWRRMGKRFMLKTFCAVALVSGFSL 101 +L G G++ + LT LP G + F +N+PF+ +R++GK F L T +A++S +L Sbjct: 57 ILDGGVVGISIIISQLTPLPLGVLTFVLNIPFFIIGYRKIGKVFALFTLYGIAVMSIVTL 116 Query: 102 ----MHPYFISYGKLDLFYSAVLGGLLIGVGFVMLFRHGASLGGINVVTLFLQDRYGLRA 157 M P DL + V GG+ +G+G ++ R+G +L G ++++ + R Sbjct: 117 VLHDMDPV-----TDDLLLATVFGGMTLGLGVGLVIRNGGALDGTEIISIIINGRTPFST 171 Query: 158 GKLQMGVDVVIVLCS 172 G++ M +++VI + + Sbjct: 172 GQIIMFINIVIFIVA 186 >SPy2155 [S] COG1284 Uncharacterized conserved protein Spy Streptococcus pyogenes M1 GAS Length = 313 Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 9/160 (5%) Query: 13 RHRSYEDVLALVAGTLFISLGVNMYTQVGLLTGSTA-GLAF----LAHYLTG--LPFGAV 65 R + E + A + + S+ VN + Q G + S A GLA L+H L G P Sbjct: 33 REKYAEKISASLLYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFA 92 Query: 66 FFTINLPFYYFAWRRMGKRFMLKTFCAVALVSGFSLMHPYFISYGKLDLFYSAVLGGLLI 125 F+ IN+P AW ++G +F + TF V++ S F + P D +A+ GGL++ Sbjct: 93 FYLINIPLLILAWYKIGHQFTIFTFITVSMSSFFIQIMPQVTL--TTDPLINAIFGGLVM 150 Query: 126 GVGFVMLFRHGASLGGINVVTLFLQDRYGLRAGKLQMGVD 165 G+G + S GG ++V+L L+ R G G L + V+ Sbjct: 151 GMGIGTGLKSRISSGGTDIVSLTLRKRTGKDVGSLSLMVN 190 >SPy2153 [S] COG1284 Uncharacterized conserved protein Spy Streptococcus pyogenes M1 GAS Length = 290 Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 51/197 (25%), Positives = 93/197 (47%), Gaps = 10/197 (5%) Query: 16 SYEDVLALVAGTLFISLGVNMYT--------QVGLLTGSTAGLAFLAHYLTGLPFGAVFF 67 ++ D L + I+LGV +YT L G AG+ + H G+ Sbjct: 2 AHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGITLILHAHFGINPAYSSL 61 Query: 68 TINLPFYYFAWRRMGKRFMLKTFCAVALVSGFSLM-HPYFISYG-KLDLFYSAVLGGLLI 125 NLP + + GKR + T L+S F M I G + D+ AV+ GL Sbjct: 62 LFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPIELGLENDMMLVAVVAGLFS 121 Query: 126 GVGFVMLFRHGASLGGINVVTLFLQDRYGLRAGKLQMGVDVVIVLCSLWVVAPKVLLASI 185 G+G ++FR+GA+ GG +++ ++++G + G+ + VD +++ SL V K +L ++ Sbjct: 122 GIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLVDALVLTASLTYVDLKHMLYTL 181 Query: 186 LGAVTANLIIALNHRAG 202 + + + +I++ G Sbjct: 182 VASFVFSQMISVVQNGG 198