BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0058.p (404 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2949 [GEPR] COG0477 Permeases of the major facilitator superf... 194 3e-49 RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 159 1e-38 yhaU [GEPR] COG0477 Permeases of the major facilitator superfami... 148 2e-35 ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfam... 148 2e-35 ECs4005 [GEPR] COG0477 Permeases of the major facilitator superf... 148 2e-35 STM1543 [GEPR] COG0477 Permeases of the major facilitator superf... 142 2e-33 STM3698 [GEPR] COG0477 Permeases of the major facilitator superf... 140 7e-33 BS_yjmG [GEPR] COG0477 Permeases of the major facilitator superf... 137 3e-32 ZyjiZ [GEPR] COG0477 Permeases of the major facilitator superfam... 137 6e-32 ECs5316 [GEPR] COG0477 Permeases of the major facilitator superf... 137 7e-32 >lin2949 [GEPR] COG0477 Permeases of the major facilitator superfamily Lin Listeria innocua Length = 401 Score = 194 bits (493), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 123/399 (30%), Positives = 214/399 (53%), Gaps = 4/399 (1%) Query: 5 VRKGKYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 V+ K+ +VL++L++G+ Y+D+ I + ++ + PS G++LS+FFLGY+L Sbjct: 4 VKGEKHSLMVLLVLFIGYTSVYVDKYTIGISLVTVSQDLGFDPSQKGLILSAFFLGYTLF 63 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGV-GEGAFPAASV 123 Q+P G+L +R G+RPV+ ISI++ LF + G +S+ LV+IRF+ G G +P + Sbjct: 64 QIPMGYLNNRIGARPVLAISIIIVGLFLIIFGFGYSLLFLVVIRFLSGAFGHAGYPPSVS 123 Query: 124 KGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGVVFALV 183 ++ + ++R S +++S+ + + PLLIA L+L GWR +++IGI V+F + Sbjct: 124 NYISLHIPLNKRGFAQSAMLASSGFAAFIGPLLIAQLLLSVGWRNTYYWIGIV-VIFIGL 182 Query: 184 YWFCVRPVRPGVGGAGAINKQA--FMALMKMPLMWQIVAVWFGLSIINKGLDTWMPTYLM 241 V P P + + K F L+K +W ++ ++ N GL +W+ +YL Sbjct: 183 LILLVVPKAPKIDKSTQKEKIKVPFSELLKDKQLWILLLSALFINAANYGLTSWLASYLN 242 Query: 242 TVRGLNLKAVGLLLPLPYIMAGLSTAIGGWVMVRFFDGREKLLLIGSSLLTAVFVYCMYS 301 RG+++ V + L + ++ IGG+ + RFF G+E +++ S+L A VY +Y Sbjct: 243 EARGISISEVSYISSLAGLCILIAGVIGGYFISRFFKGKEPIVIFTFSVLGAFTVYGVYL 302 Query: 302 AASVEGVIAWQCLAYFFKSFVLATCIALPTKMLQAQLVGSGVGMVNLGGQLAGFISPLVI 361 + I CL F T + LP K+ + + + +N GG L GF +P++I Sbjct: 303 FDQLMLSIICLCLCNIFLIMAFTTLMGLPHKLFKQSHIATKYAAINSGGVLGGFFAPMII 362 Query: 362 GFLVSAFANYDYAFSFLIGAAFFSVLVSLFIRTHKSDSQ 400 G LV+A +Y AF FL S ++ L I+ S+ Sbjct: 363 GDLVNATNSYQSAFLFLALTFLVSGIIVLAIKKRSVISE 401 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 159 bits (401), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 126/411 (30%), Positives = 201/411 (48%), Gaps = 32/411 (7%) Query: 6 RKGKYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLLQ 65 ++ K ++LV L++ ++YIDR ++ AA I EFHL ++G+++S+FF Y+LLQ Sbjct: 9 QRSKVRWLVAGLMWAAIAINYIDRTVLSAAAPHIQKEFHLSAVEMGVVMSAFFWSYALLQ 68 Query: 66 LPGGWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGVGE-GAFPAASVK 124 LP G LADR+G + V+ ++L WSL T VTG+A SLV +R GVGE GA+P S Sbjct: 69 LPAGILADRFGQKKVLGFAVLWWSLATAVTGLATGFKSLVGLRVALGVGEAGAYP--SNA 126 Query: 125 GVAEN-FSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGVVFALV 183 G+ F + ER ++++ S + +GS +A LIA L++ + W+ F G G+V+ +V Sbjct: 127 GITSRWFPKQERATVAAIFDSGSKLGSAIALPLIAWLLVTFDWKITFTVAGSLGIVWCVV 186 Query: 184 YWFCVRP---VRPGVGGAGAINKQA-----------FMALMKMPLMWQIVAVWFGLSIIN 229 + R GV A + Q M K+ + A+ G +IN Sbjct: 187 WALVFRDSPAEHEGVNAAELAHIQKGLPPARGADAPAMPWTKLLTHRNVWAMCIGFFMIN 246 Query: 230 KG---LDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIGGWVMVRFF-DGR----- 280 TW+PTYL+ RG+ L +G + LP ++ GW R + GR Sbjct: 247 YNSYFFITWLPTYLVKERGMGLMEMGFMASLPLFVSMFVEVFAGWASDRVYASGRLSLTA 306 Query: 281 -EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFVLATCIALPTKMLQAQLV 339 KL L+ ++ + ++ ++V VI C+A + + ALP + V Sbjct: 307 TRKLFLVIGLVMASSIGLAAFAQSAVVAVIL-LCIAKSGTTVAASQVWALPADVAPGNTV 365 Query: 340 GSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSF---LIGAAFFSVL 387 G+ N + G + P+V G +V A ++ A F LIG A + L Sbjct: 366 SMVAGLQNSVSNMGGVVGPIVTGAIVGATGSFIPALVFSAALIGLAILNYL 416 >yhaU [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 444 Score = 148 bits (374), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 122/442 (27%), Positives = 207/442 (46%), Gaps = 53/442 (11%) Query: 6 RKGKY-KYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 +KG + +YL+L+++++ V+Y DRA ++ A T++A E L +G + S+F Y L+ Sbjct: 10 KKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLM 69 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTG------MAWSVTSLVMIRFIFGVGEGAF 118 Q+PGGWL D++GS+ V S+ WSLFT + G +AW+ S+ +RF+ G E Sbjct: 70 QIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPS 129 Query: 119 PAASVKGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGV 178 A+ + VA F ER S++ S+ Y L L+ L +GW VF +G+ G Sbjct: 130 FPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGF 189 Query: 179 VFA-----LVYWFCVRP---------------------VRPGVGGAGAINKQAFMALMKM 212 V L++ P +PG A L+ Sbjct: 190 VLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSN 249 Query: 213 PLMWQIVAVWFGLSIINK---GLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIG 269 +M + V+FG IN TW P YL+ +G+++ VGL+ +P + G + + Sbjct: 250 RMM---LGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIP-ALCGFAGGVL 305 Query: 270 GWVMVRFFDGR-------EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFV 322 G V + R KL ++ LL + + C Y+ + V+ LA+F K F Sbjct: 306 GGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTL-VVMLMALAFFGKGF- 363 Query: 323 LATCIALP--TKMLQAQLVGSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSFLIG 380 + P + ++VG G+ N+ G +A ++PLVIG+LVS +++ A F+ Sbjct: 364 --GALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGC 421 Query: 381 AAFFSVLVSLFIRTHKSDSQMQ 402 +A +++ LF+ ++Q Sbjct: 422 SALMAMVCYLFVVGDIKRMELQ 443 >ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 444 Score = 148 bits (374), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 122/442 (27%), Positives = 207/442 (46%), Gaps = 53/442 (11%) Query: 6 RKGKY-KYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 +KG + +YL+L+++++ V+Y DRA ++ A T++A E L +G + S+F Y L+ Sbjct: 10 KKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLM 69 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTG------MAWSVTSLVMIRFIFGVGEGAF 118 Q+PGGWL D++GS+ V S+ WSLFT + G +AW+ S+ +RF+ G E Sbjct: 70 QIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPS 129 Query: 119 PAASVKGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGV 178 A+ + VA F ER S++ S+ Y L L+ L +GW VF +G+ G Sbjct: 130 FPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGF 189 Query: 179 VFA-----LVYWFCVRP---------------------VRPGVGGAGAINKQAFMALMKM 212 V L++ P +PG A L+ Sbjct: 190 VLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSN 249 Query: 213 PLMWQIVAVWFGLSIINK---GLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIG 269 +M + V+FG IN TW P YL+ +G+++ VGL+ +P + G + + Sbjct: 250 RMM---LGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIP-ALCGFAGGVL 305 Query: 270 GWVMVRFFDGR-------EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFV 322 G V + R KL ++ LL + + C Y+ + V+ LA+F K F Sbjct: 306 GGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTL-VVMLMALAFFGKGF- 363 Query: 323 LATCIALP--TKMLQAQLVGSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSFLIG 380 + P + ++VG G+ N+ G +A ++PLVIG+LVS +++ A F+ Sbjct: 364 --GALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGC 421 Query: 381 AAFFSVLVSLFIRTHKSDSQMQ 402 +A +++ LF+ ++Q Sbjct: 422 SALMAMVCYLFVVGDIKRMELQ 443 >ECs4005 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 444 Score = 148 bits (374), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 122/442 (27%), Positives = 207/442 (46%), Gaps = 53/442 (11%) Query: 6 RKGKY-KYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 +KG + +YL+L+++++ V+Y DRA ++ A T++A E L +G + S+F Y L+ Sbjct: 10 KKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLM 69 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTG------MAWSVTSLVMIRFIFGVGEGAF 118 Q+PGGWL D++GS+ V S+ WSLFT + G +AW+ S+ +RF+ G E Sbjct: 70 QIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPS 129 Query: 119 PAASVKGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGV 178 A+ + VA F ER S++ S+ Y L L+ L +GW VF +G+ G Sbjct: 130 FPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGF 189 Query: 179 VFA-----LVYWFCVRP---------------------VRPGVGGAGAINKQAFMALMKM 212 V L++ P +PG A L+ Sbjct: 190 VLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSN 249 Query: 213 PLMWQIVAVWFGLSIINK---GLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIG 269 +M + V+FG IN TW P YL+ +G+++ VGL+ +P + G + + Sbjct: 250 RMM---LGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIP-ALCGFAGGVL 305 Query: 270 GWVMVRFFDGR-------EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFV 322 G V + R KL ++ LL + + C Y+ + V+ LA+F K F Sbjct: 306 GGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTL-VVMLMALAFFGKGF- 363 Query: 323 LATCIALP--TKMLQAQLVGSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSFLIG 380 + P + ++VG G+ N+ G +A ++PLVIG+LVS +++ A F+ Sbjct: 364 --GALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGC 421 Query: 381 AAFFSVLVSLFIRTHKSDSQMQ 402 +A +++ LF+ ++Q Sbjct: 422 SALMAMVCYLFVVGDIKRMELQ 443 >STM1543 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 428 Score = 142 bits (357), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 111/426 (26%), Positives = 211/426 (49%), Gaps = 32/426 (7%) Query: 5 VRKGKYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLL 64 +++ +L++ LL++ + ++Y+DR+A++ A I E +++G++ S+FF+GY+L Sbjct: 1 MKRKTMGWLIVFLLFIVYMLNYMDRSALSITAPLIEKELGFNAAEMGMIFSAFFIGYALF 60 Query: 65 QLPGGWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGVGEGAFPAASVK 124 GGW +D+ G + V +I+ LLWS+F G+TG+ + +++++R +FG+ EG AA K Sbjct: 61 NFIGGWASDKVGPKTVFLIAALLWSVFCGLTGLVTGLWTMLIVRVLFGMAEGPVSAAGNK 120 Query: 125 GVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGVVFALVY 184 + SR E + + + +G ++ ++ L L GWR F I + G+V+ L++ Sbjct: 121 IINNWISRKESATAIGIFSAGSPLGGAVSGPIVGLLALSLGWRPAFGIIFLFGLVWVLLW 180 Query: 185 WFCVRPVRPGVGGAGAINKQ-------------------AFMALMKMPLMWQIVAVWFGL 225 +F V +P + A ++ + MK P++W +F Sbjct: 181 YFIVSD-KPTMSKRLAPEERIDFENHEDVILSDDGRATPSLGYYMKQPMVWATTLAFFSY 239 Query: 226 SIINKGLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIGGW---VMVRFFDGR-- 280 + I TW P+YL L++K + + +P+++ + +GG V+ R Sbjct: 240 NYILFFFLTWFPSYLNHSLHLDIKEISIATVIPWVIGAIGMVLGGVCSDVIYRITGNALL 299 Query: 281 EKLLLIGSSLL-TAVFVYCMYSAASVEGVIAWQCLAYFFKSFVLATCIALPTKMLQAQLV 339 + L++G L AV V + +++ I ++ F A+ ++ V Sbjct: 300 SRRLILGVCLAGAAVCVAVSGTVSTIGSAITLMSVSLFLLYLTGPIYWAVIQDVVHKDKV 359 Query: 340 GSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSFLIGAAFF--SVLVSLFIRT--- 394 GS G ++ ++G I PLV GF+V YDYAF +L GA S+LV +F+++ Sbjct: 360 GSVGGAMHGLANISGIIGPLVTGFIVQFSGKYDYAF-YLAGAIAIVSSLLVFVFVKSKGF 418 Query: 395 HKSDSQ 400 ++SQ Sbjct: 419 KANESQ 424 >STM3698 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 436 Score = 140 bits (352), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 122/428 (28%), Positives = 211/428 (49%), Gaps = 42/428 (9%) Query: 1 MDAAVRKGKYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLG 60 M+ +++ K ++ +L+ L+L +Y DRA ++ A ++ E P +G+ SSF + Sbjct: 1 MNTIIKRTKVRHTILIFLFLATVFNYADRATLSVVAPIMSKELGFDPEAMGLAFSSFGIA 60 Query: 61 YSLLQLPGGWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGVGEG---- 116 Y ++QLPGGWL DRYGSR V +++ WSL T G + S +++ I + G Sbjct: 61 YVIMQLPGGWLLDRYGSRLVYGCALIGWSLVTMFQGTIYLYGSPLIVLVILRLLMGAIEA 120 Query: 117 -AFPAASVKGVAENFSRDERPKMSSLLMSSNYIG-SMLAPLLIAPLILHY-GWRAVFHYI 173 AFPA S V + F +ER ++S+ ++ YI ++ PL+ +ILH W VF+YI Sbjct: 121 PAFPANSRLSV-QWFPNNERGFVTSVYQAAQYISLGIITPLMT--IILHNLSWHFVFYYI 177 Query: 174 GIAGVVFALVYWFCVR-PV------------------RPGVGGAGAINKQAFMALMKMPL 214 G GV+ + + V+ P+ P +G K F + + + Sbjct: 178 GAIGVMLGIFWLMKVKDPMHHPKVNQAEIDYIRSGGGEPSLGCKKEPQKITFAQIKTVCV 237 Query: 215 MWQIVAVWFG---LSIINKGLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIGG- 270 ++ V+ G ++ I TW PTYL +G+++ VG + +P I + +GG Sbjct: 238 NRMMIGVYIGQFCVTSITWFFLTWFPTYLYQAKGMSILKVGFVASIPAIAGFIGGLLGGV 297 Query: 271 ---WVMVRFFDGR--EKLLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSF-VLA 324 W++ R + KL +I LL+ V V Y+++ VIA LA+F K F L Sbjct: 298 FSDWLLKRGYSLTVARKLPVICGMLLSCVIVIANYTSSEFV-VIAAMSLAFFAKGFGNLG 356 Query: 325 TCIALPTKMLQAQLVGSGVGMVNLGGQLAGFISPLVIGFLVSAFANYDYAFSFLIGAAFF 384 C+ T +++G G+ N+ G +A ++PLVIG +++ ++D+A ++ Sbjct: 357 WCVLSDTS--PKEVLGIAGGVFNMCGNMASIVTPLVIGVILANTQSFDFAILYVGSMGLI 414 Query: 385 SVLVSLFI 392 ++ LFI Sbjct: 415 GLISYLFI 422 >BS_yjmG [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 422 Score = 137 bits (346), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 111/406 (27%), Positives = 201/406 (49%), Gaps = 25/406 (6%) Query: 9 KYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSLLQLPG 68 K K V++ L+L ++Y+DR+A++ AA I + L + +G++ SSF +GY++ G Sbjct: 4 KDKLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLG 63 Query: 69 GWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGVGEGAFPAASVKGVAE 128 G +DRYG++ + +++++WSLF+G +A+ SL++IR +FG+GEG A K V Sbjct: 64 GVASDRYGAKLTLFVAMVVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNN 123 Query: 129 NFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGVVFALVYWFCV 188 F +R + + S +G ++ ++ + + + W+ F I I G+++A V WF Sbjct: 124 WFPPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFSWKVSFVLIMIIGLIWA-VLWFKF 182 Query: 189 RPVRP--GVGGAGAINKQAFMALMKMPLMWQIVA--------VWFGLSIINKGLDTWMPT 238 +P + A AI + K+PL + + +F + I TW P+ Sbjct: 183 VKEKPQETIKEAPAIKAETSPG-EKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFPS 241 Query: 239 YLMTVRGLNLKAVGLLLPLPYIMAGLSTAIGGWVMVRFFDGREKLLLIGSSLLTAVFVYC 298 YL+ RGL+++++ ++ +P+I+ + A GG+V + + ++ S V V C Sbjct: 242 YLVDERGLSVESMSVITVIPWILGFIGLAAGGFVSDYVYKKTARKGVLFSR--KVVLVTC 299 Query: 299 MYSA----------ASVEGVIAWQCLAYFFKSFVLATCIALPTKMLQAQLVGSGVGMVNL 348 ++S+ A+ G + L+ FF A A+ ++ VGS G ++ Sbjct: 300 LFSSAVLIGFAGLVATTAGAVTLVALSVFFLYLTGAIYWAVIQDVVDQNNVGSVGGFMHF 359 Query: 349 GGQLAGFISPLVIGFLVSAFANYDYAFSFLIG-AAFFSVLVSLFIR 393 AG I P + GF+V + AF G A F S+ V F+R Sbjct: 360 LANTAGIIGPALTGFIVDQTGTFSGAFLLAGGLAVFASLAVIRFVR 405 >ZyjiZ [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 453 Score = 137 bits (344), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 97/392 (24%), Positives = 182/392 (46%), Gaps = 21/392 (5%) Query: 4 AVRKGKYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSL 63 + R + + ++LL+ ++Y+DR++++ A I E L +++G LLS F L Y + Sbjct: 33 STRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGI 92 Query: 64 LQLPGGWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGVGEGAFPAASV 123 QLP G L DR G R ++ + + WSLF ++GM S T V++R G+GE V Sbjct: 93 AQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGV 152 Query: 124 KGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGVVFALV 183 K + + F+ ER + +++ IG ++P ++A ++L GWR +F IG+ G+ A+ Sbjct: 153 KVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIG 212 Query: 184 YWFCVR--------PVRPGVGGAGAINKQ-------AFMALMKMPLMWQIVAVWFGLSII 228 ++ R V AG++N + + +L + MW ++ + G++ Sbjct: 213 WYMLYRNREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYT 272 Query: 229 NKGLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIGGWVMVRFFDG------REK 282 W+P YL T L+LK+ GL+ +P++ + G+V G K Sbjct: 273 AWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRK 332 Query: 283 LLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFVLATCIALPTKMLQAQLVGSG 342 + +I +A F + A + + +A F F +C L + +++ S Sbjct: 333 ICIIAGMFCSAAFTLIVPQATTSMMAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASV 392 Query: 343 VGMVNLGGQLAGFISPLVIGFLVSAFANYDYA 374 + N + +P++ GF+V ++ A Sbjct: 393 GSIQNFASFICASFAPIITGFIVDTTHSFRLA 424 >ECs5316 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 453 Score = 137 bits (344), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 97/392 (24%), Positives = 182/392 (46%), Gaps = 21/392 (5%) Query: 4 AVRKGKYKYLVLVLLYLGWCVSYIDRAAITFAATQIASEFHLKPSDLGILLSSFFLGYSL 63 + R + + ++LL+ ++Y+DR++++ A I E L +++G LLS F L Y + Sbjct: 33 STRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGI 92 Query: 64 LQLPGGWLADRYGSRPVIVISILLWSLFTGVTGMAWSVTSLVMIRFIFGVGEGAFPAASV 123 QLP G L DR G R ++ + + WSLF ++GM S T V++R G+GE V Sbjct: 93 AQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGV 152 Query: 124 KGVAENFSRDERPKMSSLLMSSNYIGSMLAPLLIAPLILHYGWRAVFHYIGIAGVVFALV 183 K + + F+ ER + +++ IG ++P ++A ++L GWR +F IG+ G+ A+ Sbjct: 153 KVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIG 212 Query: 184 YWFCVR--------PVRPGVGGAGAINKQ-------AFMALMKMPLMWQIVAVWFGLSII 228 ++ R V AG++N + + +L + MW ++ + G++ Sbjct: 213 WYMLYRNREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYT 272 Query: 229 NKGLDTWMPTYLMTVRGLNLKAVGLLLPLPYIMAGLSTAIGGWVMVRFFDG------REK 282 W+P YL T L+LK+ GL+ +P++ + G+V G K Sbjct: 273 AWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRK 332 Query: 283 LLLIGSSLLTAVFVYCMYSAASVEGVIAWQCLAYFFKSFVLATCIALPTKMLQAQLVGSG 342 + +I +A F + A + + +A F F +C L + +++ S Sbjct: 333 ICIIAGMFCSAAFTLIVPQATTSMMAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASV 392 Query: 343 VGMVNLGGQLAGFISPLVIGFLVSAFANYDYA 374 + N + +P++ GF+V ++ A Sbjct: 393 GSIQNFASFICASFAPIITGFIVDTTHSFRLA 424