BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0056.p (294 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0683 [M] COG1091 dTDP-4-dehydrorhamnose reductase Rso Ralston... 234 1e-61 PA5162 [M] COG1091 dTDP-4-dehydrorhamnose reductase Pae Pseudomo... 227 3e-59 alr4490 [M] COG1091 dTDP-4-dehydrorhamnose reductase Nos Nostoc ... 221 2e-57 STM2096 [M] COG1091 dTDP-4-dehydrorhamnose reductase Sty Salmone... 220 3e-57 XF0258 [M] COG1091 dTDP-4-dehydrorhamnose reductase Xfa Xylella ... 216 4e-56 rfbD [M] COG1091 dTDP-4-dehydrorhamnose reductase Eco Escherichi... 216 5e-56 AGl531 [M] COG1091 dTDP-4-dehydrorhamnose reductase Atu Agrobact... 212 9e-55 mlr7553 [M] COG1091 dTDP-4-dehydrorhamnose reductase Mlo Mesorhi... 198 9e-51 sll1395 [M] COG1091 dTDP-4-dehydrorhamnose reductase Syn Synecho... 198 1e-50 SMb21327 [M] COG1091 dTDP-4-dehydrorhamnose reductase Sme Sinorh... 186 4e-47 >RSc0683 [M] COG1091 dTDP-4-dehydrorhamnose reductase Rso Ralstonia solanacearum Length = 305 Score = 234 bits (598), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 130/273 (47%), Positives = 172/273 (63%) Query: 2 LARHGELLAPSSRELDLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAVNAL 61 LA GE++A DL AL+ +++ RP +IVN AAYTAVDKAE+D A AVN + Sbjct: 28 LAPLGEVIALDRAACDLTRPDALRRLVREHRPDVIVNPAAYTAVDKAETDAETAFAVNGM 87 Query: 62 APMILAQQAQMLGAPLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIAAHC 121 A +LA++A+ LG+ LVH+STDYVFDG A YVETD P +VYG++KLAGEQ IAA Sbjct: 88 AAGVLAEEARALGSLLVHYSTDYVFDGSKAAAYVETDAVNPQSVYGKSKLAGEQAIAASG 147 Query: 122 DAYWILRTSWVYGRYGSNFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARMLAHG 181 A +LRT WV G +G NF KTM +L ER+ L V+ DQ GAPT IAD A+++A Sbjct: 148 AAALVLRTCWVAGAHGGNFAKTMLKLGRERDSLRVIADQFGAPTTAALIADVTAQIVARF 207 Query: 182 ADAQQSVRETTGLYHLSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDAYPAI 241 + GLYHL+A G T+WHG+A +L+ + +G +DP + I + AYP Sbjct: 208 WLSGDRAAFPGGLYHLAAAGETTWHGYATAVLRYAKVRGLELKVDPERIEAIPATAYPLP 267 Query: 242 AQRPRNSRLDTGLLRRTFSLSLPTWEEALERCL 274 A RP NSR+DTG L TF + LP W++ + L Sbjct: 268 APRPANSRMDTGKLTETFGIHLPDWQQGVHLLL 300 >PA5162 [M] COG1091 dTDP-4-dehydrorhamnose reductase Pae Pseudomonas aeruginosa Length = 302 Score = 227 bits (578), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 132/265 (49%), Positives = 161/265 (60%) Query: 2 LARHGELLAPSSRELDLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAVNAL 61 LA GELL R DLAD + L ++ RP IVNA AYTAVDKAESD A +NA Sbjct: 21 LAPLGELLVCDRRRADLADPEGLARLVRAERPQFIVNAGAYTAVDKAESDADNARLINAR 80 Query: 62 APMILAQQAQMLGAPLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIAAHC 121 A +LA++A GA LVH+STDYVFDG + P+ E PTGPL+VYG+TKL GEQ I A Sbjct: 81 AVAVLAEEAAACGAWLVHYSTDYVFDGAGSVPFAEDAPTGPLSVYGQTKLEGEQAIRASG 140 Query: 122 DAYWILRTSWVYGRYGSNFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARMLAHG 181 + I RTSWVY G NF KTM RLAG+R+ L VV DQ GAPT IAD A+ L Sbjct: 141 CRHLIFRTSWVYAARGGNFAKTMLRLAGQRDELKVVADQFGAPTSAELIADVTAQALQRL 200 Query: 182 ADAQQSVRETTGLYHLSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDAYPAI 241 + +G YHL A G TSWH +A+ +++ +G P V PIA++ YP Sbjct: 201 CWDVELAARASGTYHLVASGETSWHLYARFVIEQALERGWELQATPQRVLPIATEDYPVP 260 Query: 242 AQRPRNSRLDTGLLRRTFSLSLPTW 266 A+RP NSRLD L++ F L LP W Sbjct: 261 AKRPANSRLDNRKLQQVFGLVLPDW 285 >alr4490 [M] COG1091 dTDP-4-dehydrorhamnose reductase Nos Nostoc sp. PCC 7120 Length = 294 Score = 221 bits (563), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 117/276 (42%), Positives = 169/276 (61%), Gaps = 10/276 (3%) Query: 1 MLARHGELLAPSSRELDLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAVNA 60 +LA ++++ + +DL +L+ +++ +P +I+NAAAYTAVDKAE++ A A+NA Sbjct: 21 LLAPRYKIISVARPRIDLTQADSLRQIIREVQPQIIINAAAYTAVDKAETEPEIATAINA 80 Query: 61 LAPMILAQQAQMLGAPLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIAAH 120 AP I+A+++Q LG+ L+H STDYVFDG+ + PY ETDPT PL+VYG+TKLAGE I Sbjct: 81 TAPQIIAEESQKLGSFLIHISTDYVFDGQQSHPYQETDPTNPLSVYGKTKLAGEIAIQQT 140 Query: 121 CDAYWILRTSWVYGRYG-SNFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARMLA 179 + ILRT+WVYG +G SNF+KTM RL ER+ + VV DQIG+PTW IADT+A+++ Sbjct: 141 HPHHIILRTAWVYGSFGKSNFVKTMLRLGAERQEIRVVKDQIGSPTWAQDIADTIAQVIP 200 Query: 180 HGADAQQSVRETTGLYHLSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDAYP 239 + E +G YH + G SW+ FA I +Q L + PI + YP Sbjct: 201 Q-------IPEISGTYHYTNTGVISWYEFAVAIFA--ESQKLGFPLTVQQIIPITTAEYP 251 Query: 240 AIAQRPRNSRLDTGLLRRTFSLSLPTWEEALERCLH 275 +A RP S L + + + P W++ L L Sbjct: 252 TLAPRPAYSVLACEKMSQVLGTAPPHWQQRLRLMLQ 287 >STM2096 [M] COG1091 dTDP-4-dehydrorhamnose reductase Sty Salmonella typhimurium LT2 Length = 299 Score = 220 bits (560), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 126/277 (45%), Positives = 168/277 (60%), Gaps = 10/277 (3%) Query: 2 LARHGELLA--PSSREL--DLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEA 57 LA G L+A S+E D ++ + + +++ RP +IVNAAA+TAVDKAES+ A+ Sbjct: 20 LAPVGNLIALDVHSKEFCGDFSNPKGVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQL 79 Query: 58 VNALAPMILAQQAQMLGAPLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGI 117 +NA + +A+ A GA +VH+STDYVF G P+ ETD T PLNVYG+TKLAGE+ + Sbjct: 80 LNATSVEAIAKAANETGAWVVHYSTDYVFPGTGDIPWQETDATSPLNVYGKTKLAGEKAL 139 Query: 118 AAHCDAYWILRTSWVYGRYGSNFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARM 177 +C + I RTSWVY G+NF KTM RLA ER+ L+V++DQ GAPT A+ LA Sbjct: 140 QDNCPKHLIFRTSWVYAGKGNNFAKTMLRLAKERQTLSVINDQYGAPTG----AELLADC 195 Query: 178 LAHGADAQQSVRETTGLYHLSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDA 237 AH + E GLYHL AGG T+WH +A + R G T L + + + A Sbjct: 196 TAHAIRVALNKPEVAGLYHLVAGGTTTWHDYAALVFDEARKAGITLALTE--LNAVPTSA 253 Query: 238 YPAIAQRPRNSRLDTGLLRRTFSLSLPTWEEALERCL 274 YP A RP NSRL+T +R F L LP WE ++R L Sbjct: 254 YPTPASRPGNSRLNTEKFQRNFDLILPQWELGVKRML 290 >XF0258 [M] COG1091 dTDP-4-dehydrorhamnose reductase Xfa Xylella fastidiosa 9a5c Length = 302 Score = 216 bits (551), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 126/276 (45%), Positives = 161/276 (58%), Gaps = 12/276 (4%) Query: 2 LARHGELLAPSSRELDLADR---QALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAV 58 + R G L P+ RE AD + L+ L RP +VNAAAYTAVD+AES+ + Sbjct: 28 VTRSGRL--PNGRECVQADFDRPETLRPLLDAQRPAQVVNAAAYTAVDRAESEPDVVFRI 85 Query: 59 NALAPMILAQQAQMLGAPLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIA 118 NA AP ++A G PLVH+STDYVFDG+ PY DP PLN+YG +KLAGE+ + Sbjct: 86 NAQAPGVIAHWCARHGVPLVHYSTDYVFDGQGTSPYGVDDPVAPLNIYGASKLAGERAVR 145 Query: 119 AHCDAYWILRTSWVYGRYGSNFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARML 178 A ILRTSWVY +G NFL+TM RL E L VV DQIG PT IAD A++L Sbjct: 146 AAGGCSLILRTSWVYAAHGHNFLRTMLRLGATSERLPVVADQIGTPTAAGLIADVTAQLL 205 Query: 179 AHGADAQQSVRETTGLYHLSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDAY 238 A G ++ + G++HL+A G TSWHGFA+ I +AQ ++ V+ IAS Y Sbjct: 206 AGGGQSRHA-----GIWHLTATGQTSWHGFAEEIFA--QAQACGLMMRVPQVQAIASVGY 258 Query: 239 PAIAQRPRNSRLDTGLLRRTFSLSLPTWEEALERCL 274 P A+RP S LDT L TF + LP W + + L Sbjct: 259 PTAARRPAYSCLDTTALVETFGIVLPDWRQGVRGVL 294 >rfbD [M] COG1091 dTDP-4-dehydrorhamnose reductase Eco Escherichia coli K12 Length = 299 Score = 216 bits (550), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 113/259 (43%), Positives = 161/259 (62%), Gaps = 6/259 (2%) Query: 17 DLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAVNALAPMILAQQAQMLGAP 76 D ++ + + ++ RP +IVNAAA+TAVDKAES+ A+ +NA + +A+ A +GA Sbjct: 39 DFSNPEGVAETVRSIRPDIIVNAAAHTAVDKAESEPEFAQLINATSVEAIAKAANEVGAW 98 Query: 77 LVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIAAHCDAYWILRTSWVYGRY 136 ++H+STDYVF G P++ETD T PLNVYG TKLAGE+ + +C + I RTSWVY Sbjct: 99 VIHYSTDYVFPGNGDMPWLETDATAPLNVYGETKLAGEKALQEYCAKHLIFRTSWVYAGK 158 Query: 137 GSNFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARMLAHGADAQQSVRETTGLYH 196 G+NF KTM RLA ERE L V++DQ GAPT A+ LA AH + + GLYH Sbjct: 159 GNNFAKTMLRLAKEREELAVINDQFGAPTG----AELLADCTAHAIRVALNKPDVAGLYH 214 Query: 197 LSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDAYPAIAQRPRNSRLDTGLLR 256 L A G T+W+ +A + + R G L+ + + + AYP A+RP NSRL+T + Sbjct: 215 LVASGTTTWYDYAALVFEEARKAGIPLALNK--LNAVPTTAYPTPARRPHNSRLNTEKFQ 272 Query: 257 RTFSLSLPTWEEALERCLH 275 + F+L LP W+ ++R L+ Sbjct: 273 QNFALVLPDWQVGVKRMLN 291 >AGl531 [M] COG1091 dTDP-4-dehydrorhamnose reductase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 297 Score = 212 bits (539), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 113/265 (42%), Positives = 159/265 (60%), Gaps = 12/265 (4%) Query: 15 ELDLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAVNALAPMILAQQAQMLG 74 ELDL + + L++A+P ++V+AAAYTAVDKAES+ A AVN +AQ A+ LG Sbjct: 33 ELDLVRPENVLQALREAKPDVVVSAAAYTAVDKAESEPDIAFAVNRDGAKAVAQAAKELG 92 Query: 75 APLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIAAHCDAYWILRTSWVYG 134 P++H STDYVFDG A YVE+DPTGP ++YGR+KL GE+ ++ D Y +LRT+WVY Sbjct: 93 VPVIHLSTDYVFDGSKATAYVESDPTGPTSIYGRSKLKGERAVSEATDNYVVLRTAWVYS 152 Query: 135 RYGSNFLKTMWRLAGEREYLTVVDDQIGAPTW---THTIADTLARMLAHGADAQQSVRET 191 YG+NF+KTM +L+ R+ + VV DQ G PT +AR L D+ S+R Sbjct: 153 EYGNNFVKTMLKLSESRDEINVVADQFGCPTSATDIAAAVVAIARKLVE--DSSASLR-- 208 Query: 192 TGLYHLSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDAYPAIAQRPRNSRLD 251 G++HLS G T+W FA++I G ++ +V I + YP A RP NSRL+ Sbjct: 209 -GIFHLSGTGETTWANFAKQIFAFSAENGGKSM----IVNDITTKQYPTPAPRPANSRLN 263 Query: 252 TGLLRRTFSLSLPTWEEALERCLHA 276 L + L LP+W+ + + A Sbjct: 264 CRKLEEIYGLKLPSWQTSTREVVTA 288 >mlr7553 [M] COG1091 dTDP-4-dehydrorhamnose reductase Mlo Mesorhizobium loti Length = 292 Score = 198 bits (504), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 114/270 (42%), Positives = 158/270 (58%), Gaps = 10/270 (3%) Query: 7 ELLAPSSRELDLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAVNALAPMIL 66 +++A +LDLA+ + + ARP ++V+AAAYTAVD+AE + A VNA+ + Sbjct: 26 DVIAIGRPQLDLANPDTVIEAIAAARPDIVVSAAAYTAVDQAEDEPDLAFRVNAVGAGKV 85 Query: 67 AQQAQMLGAPLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIAAHCDAYWI 126 AQ A LG P++H STDYVFDG ++ YVETD T P +VYG +KLAGEQ +AA + I Sbjct: 86 AQAAARLGVPVIHLSTDYVFDGSASGAYVETDATAPASVYGASKLAGEQTVAAAGPRHLI 145 Query: 127 LRTSWVYGRYGSNFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARMLAHGADAQQ 186 LRT+WVY +G NF+KTM RLA +R+ ++VV DQ G P+ IAD + H A Sbjct: 146 LRTAWVYSPFGKNFVKTMLRLAADRDEISVVADQWGNPSSALDIADA----ILHAAATLH 201 Query: 187 SVRE--TTGLYHLSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDAYPAIAQR 244 ++ G YHL+ G T+W GFA+ IL R G + A V I + YP A+R Sbjct: 202 RNKDFGAFGTYHLAGTGETNWSGFARHILDTSRVSGGPS----ARVHDIMTTDYPTKARR 257 Query: 245 PRNSRLDTGLLRRTFSLSLPTWEEALERCL 274 P NSRL + F + P W ++ E + Sbjct: 258 PANSRLSSAKFASAFGWTAPDWRQSTEAVV 287 >sll1395 [M] COG1091 dTDP-4-dehydrorhamnose reductase Syn Synechocystis Length = 280 Score = 198 bits (503), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 117/275 (42%), Positives = 155/275 (56%), Gaps = 12/275 (4%) Query: 2 LARHGELLAPSSRELDLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAVNAL 61 L+ G + + DLA L ++ P +IVN+AAYTAVD+AE++ A AVNAL Sbjct: 9 LSCFGSVQEATRASFDLAQPDVLGEKIRAFAPDIIVNSAAYTAVDRAETEPELAYAVNAL 68 Query: 62 APMILAQQAQMLGAPLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIAAHC 121 AP +A+ A+ +GA +VH STDYVFDG + PY ETD T PL VYG++K GE IA Sbjct: 69 APQAIAKVAKEIGAYVVHISTDYVFDGSQSSPYRETDATNPLGVYGQSKFQGEIAIADSG 128 Query: 122 DAYWILRTSWVYGRYGS-NFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARMLAH 180 + I+RT+WVYG +GS NF+KTM RL ER+ + VV DQIG PTW +A+ +A + Sbjct: 129 CNFLIVRTAWVYGVHGSGNFVKTMVRLGKERQKVRVVADQIGGPTWAKDLAEAIAALTEQ 188 Query: 181 GADAQQSVRETTGLYHLSAGGATSWHGFAQRILQLLRAQGETALLDPALVRPIASDAYPA 240 A G+YH S G SW+ FA I + + G L V PIA+ AYP Sbjct: 189 RAQ---------GIYHYSNSGVASWYDFAVAIFEEVENLGIP--LKVRQVVPIATAAYPT 237 Query: 241 IAQRPRNSRLDTGLLRRTFSLSLPTWEEALERCLH 275 A+RP S L + T + P W +L LH Sbjct: 238 PARRPAYSVLSHQKIVETLGSAPPHWRASLRAMLH 272 >SMb21327 [M] COG1091 dTDP-4-dehydrorhamnose reductase Sme Sinorhizobium meliloti Length = 300 Score = 186 bits (473), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 112/260 (43%), Positives = 149/260 (57%), Gaps = 8/260 (3%) Query: 16 LDLADRQALQSFLQQARPGLIVNAAAYTAVDKAESDVARAEAVNALAPMILAQQAQMLGA 75 LDL + + +++ RP L+V+AAAYTAVD+AES+ A AVNA +A+ A L Sbjct: 36 LDLTEPATILPAIERCRPDLVVSAAAYTAVDQAESEPEAAFAVNAFGAGAVAEAAACLEV 95 Query: 76 PLVHFSTDYVFDGKSARPYVETDPTGPLNVYGRTKLAGEQGIAAHCDAYWILRTSWVYGR 135 P+VH STDYVFDG R Y E D PL+VYG +KLAGE +A + ILRT WVY Sbjct: 96 PIVHISTDYVFDGSKPRSYAEGDTPAPLSVYGASKLAGESAVAEATPRHLILRTGWVYSP 155 Query: 136 YGSNFLKTMWRLAGEREYLTVVDDQIGAPTWTHTIADTLARMLAHGADAQQSVRETTGLY 195 +G NF+KT+ RLA ERE + VV DQ G P+ +AD + + A ++Q GLY Sbjct: 156 FGKNFVKTILRLAEEREDIAVVADQRGNPSSAIDLADAILDISARLTKSRQDA--AFGLY 213 Query: 196 HLSAGGATSWHGFAQRILQLLRAQGETALLDP-ALVRPIASDAYPAIAQRPRNSRLDTGL 254 HL+ G S FA+ L RA G P A VR IA+ +P A RP NS L + Sbjct: 214 HLAGSGVVSRADFARHALAASRAAG-----GPWAHVRDIATGGFPTPASRPANSSLSSAK 268 Query: 255 LRRTFSLSLPTWEEALERCL 274 TF ++P W+ ++ER + Sbjct: 269 FNATFGQAMPAWQGSVERTV 288