BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0025.p (217 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0402 [R] COG2802 Uncharacterized protein, similar to the N-te... 99 6e-21 PA4012 [R] COG2802 Uncharacterized protein, similar to the N-ter... 97 2e-20 VC2303 [R] COG2802 Uncharacterized protein, similar to the N-ter... 82 8e-16 DR2189 [R] COG2802 Uncharacterized protein, similar to the N-ter... 72 1e-12 MT0449 [R] COG2802 Uncharacterized protein, similar to the N-ter... 64 3e-10 Rv0434 [R] COG2802 Uncharacterized protein, similar to the N-ter... 64 3e-10 >RSc0402 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease Rso Ralstonia solanacearum Length = 216 Score = 99.4 bits (246), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 59/184 (32%), Positives = 95/184 (51%), Gaps = 3/184 (1%) Query: 24 STLFPEGRLPLQIFEVRYLDMIGKCIAEGSSFGVVALTQGAEVRRPGQSERFVGVGTLAH 83 + LFP G LPL+IFE RY+DM+ C+ E + FGV + +G EV + V +G +AH Sbjct: 27 TVLFPGGLLPLRIFEARYIDMVRTCLREQTPFGVCLIERGNEVAADTPTVP-VDIGCIAH 85 Query: 84 IQEWSTPSPGLMRIACLGGERFRIVQAEQQKHGLWTAQVDMMEGDRVVSIPEELGNTAQA 143 I E GL+ I G +RF++ + GL V+ + D E + A Sbjct: 86 IVECDMEQLGLLMIKARGTQRFKVRSVDTTVGGLLRGTVEPIGADLEDCKGELFDDCVNA 145 Query: 144 LENLLQSVLRQGLPDSEVPIAAPYRLDDCGWVANRWAEMMPISVELKQSLLALDNPVLRL 203 L ++ ++ + +VP+A PY WV NR E++P+ ++ KQ L+ L + +R+ Sbjct: 146 LRRIVTTL--GAREEGQVPLAEPYDWASPSWVGNRLCELLPVPLKAKQKLMELMDAGMRI 203 Query: 204 ELVQ 207 E+V Sbjct: 204 EIVH 207 >PA4012 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease Pae Pseudomonas aeruginosa Length = 197 Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 74/204 (36%), Positives = 109/204 (53%), Gaps = 21/204 (10%) Query: 16 TIPLFPLASTLFPEGRLPLQIFEVRYLDMIGKCIAEGSSFGVVALTQGAEVRRPGQS-ER 74 +PLFPL + LFP RL LQIFE RYLDMI +C+ +G+ FGVV + +G EV G++ R Sbjct: 2 KLPLFPLNAVLFPGCRLDLQIFEARYLDMISRCMKQGTGFGVVTIGEGREV---GEAPSR 58 Query: 75 FVGVGTLAHIQEWSTPSPGLMRIACLGGERFRIVQAEQQKHGLWTAQVDMMEGDRVVSIP 134 VG A +++W GL+ I GG RF+++ E Q L +++ E +P Sbjct: 59 LAMVGCEASVRDWQQRPNGLLGIRVEGGRRFQVLSVEVQADQLSVGEIEWFE-----DLP 113 Query: 135 EE-LGNTAQALENLLQSVLRQGLPDSEVPIAAPYRL--DDCGW--VANRWAEMMPISVEL 189 E+ L L LL SVL +E P+ A + + G +AN+ A ++P E Sbjct: 114 EQPLTYEHNDLAALL-SVL------AEHPMVAALEMGGEPGGQQDLANQLAYLLPFDTER 166 Query: 190 KQSLLALDNPVLRLELVQDALDEL 213 K LLAL + ++L +Q L+ L Sbjct: 167 KLELLALPDAQMQLARIQVLLEHL 190 >VC2303 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease Vch Vibrio cholerae Length = 193 Score = 82.0 bits (201), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 58/172 (33%), Positives = 81/172 (47%), Gaps = 10/172 (5%) Query: 15 QTIPLFPLASTLFPEGRLPLQIFEVRYLDMIGKCIAEGSSFGVVALTQGAEVRRPGQSER 74 + I LFPL+S + PEG++ L+IFE RY M+ +C GS FG+ + SE Sbjct: 2 EEIMLFPLSSVVLPEGKMKLRIFEPRYQRMVAQCSKTGSGFGLCLFDSKSNKNANELSE- 60 Query: 75 FVGVGTLAHIQEWSTPSPGLMRIACLGGERFRIVQAEQQKHGLWTAQVDMMEGDRVVSIP 134 GTL I ++ T S GL+ I +G RF I + + GL A V Sbjct: 61 ---FGTLVKIVDFETLSDGLLGITVVGIRRFAIRKVRVEYDGLRIATVQWFPD----WPS 113 Query: 135 EELGNTAQALENLLQSVLRQGLPDSEVPIAAPYRLDDCGWVANRWAEMMPIS 186 +EL + L LQ V RQ E+ + DD WV RW E++P+S Sbjct: 114 QELLERERFLGEQLQEVYRQFPQIGELHSLCFF--DDASWVCQRWLELLPLS 163 >DR2189 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease Dra Deinococcus radiodurans Length = 213 Score = 71.6 bits (174), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 40/92 (43%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Query: 16 TIPLFPLASTLFPEGRLPLQIFEVRYLDMIGKCIAEGSSFGVVALTQGAEVRRPGQSERF 75 ++PLFPL + LFP LPL +FE RY ++ + A G FGVV + +G + P ER Sbjct: 8 SLPLFPLPTVLFPGQALPLYVFEERYRALLRRVQASGEPFGVVWIERGRDSTLP-LHERL 66 Query: 76 VGVGTLAHIQEWSTPSPGLMRIACLGGERFRI 107 VGTLAH+ E G I +GGERFR+ Sbjct: 67 SLVGTLAHLTEAEVHEDGTSSILVVGGERFRL 98 >MT0449 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease MtC Mycobacterium tuberculosis CDC1551 Length = 218 Score = 63.5 bits (153), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 64/216 (29%), Positives = 96/216 (44%), Gaps = 34/216 (15%) Query: 19 LFPLASTLFPEGRLPLQIFEVRYLDMIGKCIAEGS-SFGVVALTQGAEVRRPGQSERFVG 77 +FPL S P+ LPL IFE RY ++ C+ FGVV +++G EV G + Sbjct: 12 MFPLESAPLPDEDLPLHIFEPRYAALVRDCMDTADPRFGVVLISRGREV---GGGDTRCD 68 Query: 78 VGTLAHIQEWSTPSPGLMRIACLGGERFRIVQ---------------AEQQKHGLWTAQV 122 VGTLA I E + G + C GER R+ +Q H + AQ+ Sbjct: 69 VGTLARITECADAGSGRYMLRCRVGERIRVCDWLPDDPYPRAKVRFWPDQPGHPVTAAQL 128 Query: 123 DMMEGDRVVSIPEELGNTAQALENLLQSVLRQGLPDSEVPIAAPYRLD--DCGWVANRWA 180 +E DRVV++ E + A+ + LP EV + P +D D G A Sbjct: 129 LEVE-DRVVALFERIA-AARGVR----------LPAREVVLGYPV-VDPADTGQRLYALA 175 Query: 181 EMMPISVELKQSLLALDNPVLRLELVQDALDELGWL 216 +P+ + ++LA + RL + DALD + + Sbjct: 176 CRVPMGPADRYAVLATPSAADRLVRLGDALDSVAAM 211 >Rv0434 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease Mtu Mycobacterium tuberculosis H37Rv Length = 217 Score = 63.5 bits (153), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 64/216 (29%), Positives = 96/216 (44%), Gaps = 34/216 (15%) Query: 19 LFPLASTLFPEGRLPLQIFEVRYLDMIGKCIAEGS-SFGVVALTQGAEVRRPGQSERFVG 77 +FPL S P+ LPL IFE RY ++ C+ FGVV +++G EV G + Sbjct: 11 MFPLESAPLPDEDLPLHIFEPRYAALVRDCMDTADPRFGVVLISRGREV---GGGDTRCD 67 Query: 78 VGTLAHIQEWSTPSPGLMRIACLGGERFRIVQ---------------AEQQKHGLWTAQV 122 VGTLA I E + G + C GER R+ +Q H + AQ+ Sbjct: 68 VGTLARITECADAGSGRYMLRCRVGERIRVCDWLPDDPYPRAKVRFWPDQPGHPVTAAQL 127 Query: 123 DMMEGDRVVSIPEELGNTAQALENLLQSVLRQGLPDSEVPIAAPYRLD--DCGWVANRWA 180 +E DRVV++ E + A+ + LP EV + P +D D G A Sbjct: 128 LEVE-DRVVALFERIA-AARGVR----------LPAREVVLGYPV-VDPADTGQRLYALA 174 Query: 181 EMMPISVELKQSLLALDNPVLRLELVQDALDELGWL 216 +P+ + ++LA + RL + DALD + + Sbjct: 175 CRVPMGPADRYAVLATPSAADRLVRLGDALDSVAAM 210