BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0003.p (300 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5382 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 299 4e-81 YPO1308 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 278 8e-75 yeiE [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 272 5e-73 ZyeiE [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 272 5e-73 ECs3049 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 272 5e-73 STM2201 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 268 1e-71 PA3398 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 247 2e-65 RSc1110 [K] COG0583 Transcriptional regulator Rso Ralstonia sola... 240 3e-63 VC2324 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 209 5e-54 VCA0542 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 169 9e-42 >PA5382 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 297 Score = 299 bits (766), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 157/293 (53%), Positives = 200/293 (68%), Gaps = 2/293 (0%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLN 60 M ++ RQLQIF AVA+ GSTTAAA+ ++LSQSA SAALNELE L +LFDRVGKRL LN Sbjct: 1 MALSFRQLQIFCAVARCGSTTAAAESISLSQSATSAALNELESQLSTRLFDRVGKRLQLN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPEA-GSELHIGASTTIGSYMLPAMIAAYRKDHAG 119 + GR+ LPQA +LD +E+QF+ A + L + AS+TIG+Y+LP ++A++ ++ G Sbjct: 61 EVGRRFLPQALRLLDGVAQLEQQFAVSAAPQASLTVAASSTIGNYVLPRLLASFEREQPG 120 Query: 120 ARVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSG 179 RV A + NT V VV F D GLIEGPCH + VEPW+ D LIVVAAP HPL S Sbjct: 121 VRVNASIGNTGSAVQDVVTFAADIGLIEGPCHEPGLRVEPWLEDSLIVVAAPGHPLA-SR 179 Query: 180 RKITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 +++ + L A WLLRE GSGTRE V HAL+ +LH+L S + G+SEAIK + A GLGIS Sbjct: 180 TQVSREALRRARWLLREPGSGTREEVSHALLGHLHYLEDSLDLGSSEAIKHSVAAGLGIS 239 Query: 240 CLSRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLGALLGFCRA 292 CLSR VVE+ + + LVEL + LP LRR FYM+ R + SP CRA Sbjct: 240 CLSRWVVEEQLATGALVELRSSLPPLRRRFYMLRQRDKFLSPGFERFWEHCRA 292 >YPO1308 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 290 Score = 278 bits (712), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 149/291 (51%), Positives = 197/291 (67%), Gaps = 4/291 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE LGVQLFDRVGKRLV N Sbjct: 1 MHITLRQLEVFTEVLKSGSTTQASVVLALSQSAVSAALADLEGQLGVQLFDRVGKRLVTN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPEAGSELHIGASTTIGSYMLPAMIAAYRKDHAGA 120 + GR L P+A +LD A IE+ F + G+ L I AS+TIG+YMLP MIA YR+D G Sbjct: 61 EHGRLLYPKALALLDQAIEIEQLFLH-DLGA-LRIAASSTIGNYMLPGMIAKYRRDFPGT 118 Query: 121 RVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSGR 180 + + N+ D+++AV +F D GLIEGPCH ++ + W+ DEL+V AAP PL + Sbjct: 119 PLELNIGNSQDVIEAVADFRGDLGLIEGPCHMPELVTQNWLRDELVVFAAPDSPLCH--K 176 Query: 181 KITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +TL L +A+W+LRE GSGTRE ++H L+ L H E GNSEAIKRA G+G+SC Sbjct: 177 ALTLVDLADADWILRERGSGTREVLDHLLLAQLPHFKLVMELGNSEAIKRAVRYGMGVSC 236 Query: 241 LSRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLGALLGFCR 291 LSR V+ D + S +LVEL+ PLP L R Y++ R + S +L L +C+ Sbjct: 237 LSRRVIADQLASGELVELNIPLPPLIRTLYLIHHRQKHISNALLRFLSYCQ 287 >yeiE [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 293 Score = 272 bits (696), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 145/290 (50%), Positives = 195/290 (67%), Gaps = 4/290 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPEAGSELHIGASTTIGSYMLPAMIAAYRKDHAGA 120 + GR L P+A +L+ A IE+ F E + I AS+TIG+Y+LPA+IA YR D+ Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFR--EDNGAIRIYASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSGR 180 + V N+ D++ AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAP PL + Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPLARG-- 176 Query: 181 KITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +TL++L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGISC Sbjct: 177 PVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISC 236 Query: 241 LSRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLGALLGFC 290 LSR V+ED +++ L E+ PLP L R + + R + S +L L +C Sbjct: 237 LSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >ZyeiE [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 272 bits (696), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 145/290 (50%), Positives = 195/290 (67%), Gaps = 4/290 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPEAGSELHIGASTTIGSYMLPAMIAAYRKDHAGA 120 + GR L P+A +L+ A IE+ F E + I AS+TIG+Y+LPA+IA YR D+ Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFR--EDNGAIRIYASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSGR 180 + V N+ D++ AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAP PL + Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPLARG-- 176 Query: 181 KITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +TL++L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGISC Sbjct: 177 PVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISC 236 Query: 241 LSRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLGALLGFC 290 LSR V+ED +++ L E+ PLP L R + + R + S +L L +C Sbjct: 237 LSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >ECs3049 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 293 Score = 272 bits (696), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 145/290 (50%), Positives = 195/290 (67%), Gaps = 4/290 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPEAGSELHIGASTTIGSYMLPAMIAAYRKDHAGA 120 + GR L P+A +L+ A IE+ F E + I AS+TIG+Y+LPA+IA YR D+ Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFR--EDNGAIRIYASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSGR 180 + V N+ D++ AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAP PL + Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPLARG-- 176 Query: 181 KITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +TL++L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGISC Sbjct: 177 PVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISC 236 Query: 241 LSRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLGALLGFC 290 LSR V+ED +++ L E+ PLP L R + + R + S +L L +C Sbjct: 237 LSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >STM2201 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 287 Score = 268 bits (685), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 142/290 (48%), Positives = 196/290 (67%), Gaps = 4/290 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ +++LSQSA SAAL +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLSLSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPEAGSELHIGASTTIGSYMLPAMIAAYRKDHAGA 120 + GR L P+A +L+ A IE+ F E + + AS+TIG+Y+LPAMIA YR+ + Sbjct: 61 EHGRLLYPRALALLEQAIEIEQLFR--EDNGAIRVYASSTIGNYILPAMIARYRQHYPAL 118 Query: 121 RVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSGR 180 + V N+ D+++AV++F VD GLIEGPCH+ ++ EPW+ DEL+V AAP PL + Sbjct: 119 PLELSVGNSQDVINAVLDFRVDIGLIEGPCHSTEIISEPWLEDELVVFAAPSSPLTQG-- 176 Query: 181 KITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +TL++L + W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGISC Sbjct: 177 PVTLEQLAASPWILRERGSGTREIVDYLLLSHLPRFHMAMELGNSEAIKHAVRHGLGISC 236 Query: 241 LSRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLGALLGFC 290 LSR V+ + +++ L E+ PLP L R + V R + S +L L +C Sbjct: 237 LSRRVIAEQLQAGTLGEVAVPLPRLVRTLWRVHHRQKHLSNALQRFLSYC 286 >PA3398 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 308 Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 131/292 (44%), Positives = 177/292 (60%), Gaps = 1/292 (0%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLN 60 MK TLRQL++F+AVAQ S + AA+ ++LSQSA S +L ELE +LFDR GKRL LN Sbjct: 1 MKFTLRQLEVFVAVAQQESVSRAAEGLSLSQSATSTSLGELERQFDCKLFDRAGKRLTLN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPEAGSELHIGASTTIGSYMLPAMIAAYRKDHAGA 120 GRQLLPQA +LD + IE + A L +GA+ TIG+Y+ +I A+ + Sbjct: 61 ALGRQLLPQAVALLDRGEEIENLLNGKTAFGSLDLGATLTIGNYLATLLIGAFMQRQPDC 120 Query: 121 RVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSGR 180 RVR V NTA +V V ++E+D GLIEG C D+EV+PWM DEL+V AP+HPL + G Sbjct: 121 RVRLHVHNTAQVVQQVAHYELDLGLIEGDCRHPDIEVQPWMEDELVVFCAPQHPLARRG- 179 Query: 181 KITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 L+RL W+LRE GSGTR + A+ + L E ++EAIKRA GLGI C Sbjct: 180 GADLERLTREAWILREQGSGTRLTFDQAMRHHPRPLNIRLELEHTEAIKRAVESGLGIGC 239 Query: 241 LSRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLGALLGFCRA 292 +SR + D LV ++TP LRR FY + + + + ++ L CR+ Sbjct: 240 ISRLALRDAFRRGSLVPVETPGLDLRRQFYFIWHKQKYQTATMREFLDLCRS 291 >RSc1110 [K] COG0583 Transcriptional regulator Rso Ralstonia solanacearum Length = 306 Score = 240 bits (613), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 134/284 (47%), Positives = 185/284 (65%), Gaps = 7/284 (2%) Query: 2 KITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLND 61 ++TLRQ +F+AVA+ +TTAA ++LSQSA SAAL ELE L LFDR G+RL LN Sbjct: 7 RVTLRQWSVFVAVARCETTTAAGAQLSLSQSAVSAALAELESALAQPLFDRHGRRLHLNA 66 Query: 62 SGRQLLPQARHMLDAAQTIERQFSDPEAGSELHIGASTTIGSYMLPAMIAAYRKDHA-GA 120 GRQLLPQA+ +LD A +E P L + AS+TIG+Y+LPA++A R+ A + Sbjct: 67 LGRQLLPQAQALLDHADALELATQQPSV--RLKLAASSTIGNYVLPALLARLRQQIAPDS 124 Query: 121 RVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSGR 180 ++ L+ NT D+VDAV+ F+VD GLIEG C + +E+EPWM DE+++VAAP HPL Sbjct: 125 QLDLLIGNTQDVVDAVLRFDVDLGLIEGSCRGEALEIEPWMEDEMVIVAAPDHPLAHG-- 182 Query: 181 KITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +++ L +A WL+RE GSGTRE ++ + + L + E G+SEAI+R A G GISC Sbjct: 183 RVSHAALRQAAWLMREPGSGTRELIDSRIAAAVGPLHVALELGHSEAIQRTVAAGYGISC 242 Query: 241 LSRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLG 284 LSR VV D + +L +D+ LP + R +V RHR P+ G Sbjct: 243 LSRYVVNDALRDGRLAIVDSGLPRIARPLLIV--RHRDKHPTRG 284 >VC2324 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 304 Score = 209 bits (533), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 108/295 (36%), Positives = 178/295 (60%), Gaps = 3/295 (1%) Query: 3 ITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLNDS 62 I+L+QL++F + Q S T AA+++ LS++A S AL+ELE LG LFDRV RLVLN Sbjct: 5 ISLKQLRVFTTITQHKSLTVAAEVLCLSKAAVSVALSELEKQLGHALFDRVNNRLVLNQE 64 Query: 63 GRQLLPQARHMLDAAQTIERQFSDPEA-GSELHIGASTTIGSYMLPAMIAAYRKDHAGAR 121 G++LLP A +L A+ I+R F++ + +L IG+S TIG+ + P +I+A+R+ H Sbjct: 65 GQKLLPMADELLQRAKDIDRLFAEQQVLTGKLRIGSSDTIGNQVAPYLISAFRQLHPHPS 124 Query: 122 VRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSGRK 181 ++N+A + +V++E+D GLIEG ++ + DE+ ++ AP HPL + R Sbjct: 125 QSLFISNSAQVCQKLVDYELDIGLIEGKTLHPELISTQFSQDEMCIICAPDHPLAQQER- 183 Query: 182 ITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISCL 241 + + ++W+LREAGSG+RE + P + H +FE +EA+ + + GLG+ CL Sbjct: 184 LVMSDFEHSDWVLREAGSGSREFFLRVIAPRIEHWIEAFELNTTEALINSVSSGLGLGCL 243 Query: 242 SRAVVEDMIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLGALLGFCRAWAQR 296 SR + + ++V L+ PL ++R F+M+V + + +P L + FC WA + Sbjct: 244 SRLAAKTPQQDGRVVILNIPL-DMKRRFWMLVHKEKYQNPLLRQFIEFCPQWASQ 297 >VCA0542 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 301 Score = 169 bits (427), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 97/273 (35%), Positives = 153/273 (56%), Gaps = 2/273 (0%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELEHLLGVQLFDRVGKRLVLN 60 M+ +L+QL +F AVA GS + AAD +AL+QSA S +L +LE +LG LF+R GK++ L Sbjct: 1 MRYSLKQLAVFDAVADCGSVSQAADKLALTQSATSMSLAQLEKMLGRPLFERQGKQMALT 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPEAGS-ELHIGASTTIGSYMLPAMIAAYRKDHAG 119 G L P+A+ +L AQ IE F D S E+ +GAS T +++P +I+ D Sbjct: 61 HWGMWLRPKAKRLLQDAQQIEMGFYDQHLLSGEIRLGASQTPAEHLVPDLISIIDSDFPE 120 Query: 120 ARVRALVANTADIVDAVVNFEVDAGLIEGPCHADDVEVEPWMMDELIVVAAPRHPLVKSG 179 R+ V +T +++ V++++ D G+IEG C + + E W D L +VA+ HP K Sbjct: 121 IRISLGVKSTKGVIEGVLDYKYDLGIIEGRCDDNRIYQEVWCRDHLTIVASAHHPFAKR- 179 Query: 180 RKITLKRLHEAEWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 ++L +L +A+W+LRE G+GTR + + P + L E+ + ++ A G ++ Sbjct: 180 ESVSLAQLEQAKWVLREQGAGTRNIFDSVIHPLIPDLDVWREYEHVPVLRTLVANGPYLT 239 Query: 240 CLSRAVVEDMIESRKLVELDTPLPTLRRHFYMV 272 CL VE IES LV L+ P + R + Sbjct: 240 CLPYLDVERFIESGLLVALNVPELNMERTLSFI 272