BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0098.p (155 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4128 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola... 115 4e-26 ZyhaF [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolas... 114 8e-26 ECs4004 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldol... 114 8e-26 RSc1591 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldol... 114 8e-26 yhaF [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase... 114 8e-26 STM3249 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldol... 112 3e-25 YPO1767 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldol... 105 5e-23 PM1535 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola... 103 1e-22 STM1106 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldol... 102 3e-22 BMEII0139 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid ald... 100 2e-21 >PA4128 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Pae Pseudomonas aeruginosa Length = 268 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 61/152 (40%), Positives = 90/152 (59%), Gaps = 1/152 (0%) Query: 1 MRFPPQGARGF-AAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVD 59 +R+PP G RG +A+ RASR+ + +E+ A+E + +VQ+E + +A L+ IAAV GVD Sbjct: 111 VRYPPAGVRGVGSALARASRWNSVAEYLNHADEQMCLLVQVENLEGLANLDAIAAVEGVD 170 Query: 60 ALFLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGY 119 +F+GP DLSAAMG GN EV+AAI D R R GK GI+ + R ++ +G Sbjct: 171 GVFIGPADLSAAMGHRGNPGHPEVQAAIEDAIHRIRTAGKAAGILSADETLARRYLELGC 230 Query: 120 DYVAIASDMGMMMRQANAFIAEFDQTAPSANA 151 +VA+ D ++MR F AP+ +A Sbjct: 231 AFVAVGVDTSLLMRSLRELAGRFKGGAPAPSA 262 >ZyhaF [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase EcZ Escherichia coli O157:H7 EDL933 Length = 256 Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 51/130 (39%), Positives = 86/130 (66%) Query: 2 RFPPQGARGFAAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVDAL 61 R+PP+G RG + HRA+ +GT +++ ++N+ ++ +VQ+E+ + ++ IAA GVD + Sbjct: 114 RYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGI 173 Query: 62 FLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGYDY 121 F+GP DL+AA+G +GN + +V+ AI + RA A GKP GI+ P A R ++ G + Sbjct: 174 FVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATF 233 Query: 122 VAIASDMGMM 131 VA+ SD+G+ Sbjct: 234 VAVGSDLGVF 243 >ECs4004 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Ecs Escherichia coli O157:H7 Length = 256 Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 51/130 (39%), Positives = 86/130 (66%) Query: 2 RFPPQGARGFAAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVDAL 61 R+PP+G RG + HRA+ +GT +++ ++N+ ++ +VQ+E+ + ++ IAA GVD + Sbjct: 114 RYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGI 173 Query: 62 FLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGYDY 121 F+GP DL+AA+G +GN + +V+ AI + RA A GKP GI+ P A R ++ G + Sbjct: 174 FVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATF 233 Query: 122 VAIASDMGMM 131 VA+ SD+G+ Sbjct: 234 VAVGSDLGVF 243 >RSc1591 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Rso Ralstonia solanacearum Length = 272 Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 58/143 (40%), Positives = 87/143 (60%), Gaps = 1/143 (0%) Query: 1 MRFPPQGARGF-AAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVD 59 MR+PP G RG +A+ RASR+ ++ RRA+ + +VQ+ETP + L+ I AV GVD Sbjct: 111 MRYPPHGNRGVGSALARASRWNRVDDYVRRADAEMCTLVQVETPRGVEHLDAILAVAGVD 170 Query: 60 ALFLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGY 119 +F+GPGDL+A+MG +G EVR I +R A GK GI+ PA+ R ++++G Sbjct: 171 GVFIGPGDLAASMGHLGEPGHPEVRQTIDRTIRRIVAAGKAAGILSADPALARHYLSLGA 230 Query: 120 DYVAIASDMGMMMRQANAFIAEF 142 +VA+ SD+ ++ R A F Sbjct: 231 TFVAVGSDVTLLARSAEQLARSF 253 >yhaF [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Eco Escherichia coli K12 Length = 256 Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 51/130 (39%), Positives = 86/130 (66%) Query: 2 RFPPQGARGFAAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVDAL 61 R+PP+G RG + HRA+ +GT +++ ++N+ ++ +VQ+E+ + ++ IAA GVD + Sbjct: 114 RYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGI 173 Query: 62 FLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGYDY 121 F+GP DL+AA+G +GN + +V+ AI + RA A GKP GI+ P A R ++ G + Sbjct: 174 FVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATF 233 Query: 122 VAIASDMGMM 131 VA+ SD+G+ Sbjct: 234 VAVGSDLGVF 243 >STM3249 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Sty Salmonella typhimurium LT2 Length = 256 Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 51/128 (39%), Positives = 84/128 (65%) Query: 2 RFPPQGARGFAAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVDAL 61 R+PP+G RG + HRA+ +GT ++ ++N+ ++ IVQ+E+ + ++ IAA GVD + Sbjct: 114 RYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDNVDAIAATEGVDGI 173 Query: 62 FLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGYDY 121 F+GP DL+AA+G +GN + +V+ I + RA+A GKP GI+ P A R ++ G + Sbjct: 174 FVGPSDLAAALGHLGNASHPDVQQTIQHIFARAKAHGKPCGILAPVEADARRYLEWGATF 233 Query: 122 VAIASDMG 129 VA+ SD+G Sbjct: 234 VAVGSDLG 241 >YPO1767 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Ype Yersinia pestis Length = 268 Score = 105 bits (261), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 58/156 (37%), Positives = 91/156 (58%), Gaps = 4/156 (2%) Query: 2 RFPPQGARGF-AAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVDA 60 R+PPQG RG +A+ RASR+ +++ ++A+E + ++Q+ET +A+ L EI AV GVD Sbjct: 112 RYPPQGIRGVGSALARASRWNRIADYVQQADEQICVLLQIETREALRNLPEILAVDGVDG 171 Query: 61 LFLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGYD 120 +F+GP DL++ MG GN EVR AI + + K GI+ TP + ++ +G Sbjct: 172 VFIGPADLASDMGFAGNPHHPEVRQAIDSAVMKIKTADKAAGILMTTPELAEYYLKLGAL 231 Query: 121 YVAIASDMGMMMRQANAFIAEF---DQTAPSANAGG 153 +VA+ D ++ R A A A F + P A +GG Sbjct: 232 FVAVGVDTTLLARTAEALAARFGVGNHHPPLAPSGG 267 >PM1535 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Pmu Pasteurella multocida Length = 266 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 52/152 (34%), Positives = 86/152 (56%), Gaps = 1/152 (0%) Query: 1 MRFPPQGARGF-AAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVD 59 + +PP+G RG +A+ RASR+ + + ++A+E + +VQ+E + L+EIA V GVD Sbjct: 108 IHYPPKGVRGVGSALARASRWNSIPHYLQQADEEICLLVQVENKTGLQNLKEIAEVDGVD 167 Query: 60 ALFLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGY 119 +F+GP DLSA++G +GN + EV+ AI A K GI+ M + ++A+G Sbjct: 168 GVFIGPADLSASLGHLGNPSHPEVQQAIEQAIATICAADKAAGILYADEKMAKHYLALGC 227 Query: 120 DYVAIASDMGMMMRQANAFIAEFDQTAPSANA 151 +VA+ D ++MR N +F + N Sbjct: 228 TFVAVGVDTSLLMRALNDLSQKFKSSNALENT 259 >STM1106 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Sty Salmonella typhimurium LT2 Length = 263 Score = 102 bits (255), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 60/155 (38%), Positives = 89/155 (57%), Gaps = 1/155 (0%) Query: 2 RFPPQGARGF-AAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVDA 60 R+PP G RG +A+ RASR+ E+ AN+A+ +VQ+ET +A++ L I V G+D Sbjct: 109 RYPPAGIRGVGSALARASRWNRIPEYLHLANDAMCVLVQIETREAMSNLASILDVDGIDG 168 Query: 61 LFLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGYD 120 +F+GP DLSA MG GN EV+AAI + + RA GK GI+ A+ + ++ +G Sbjct: 169 VFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEALAKRYLELGAL 228 Query: 121 YVAIASDMGMMMRQANAFIAEFDQTAPSANAGGPY 155 +VA+ D ++ R A A A F + A G Y Sbjct: 229 FVAVGVDTTLLARGAEALAARFGVEKKLSGASGVY 263 >BMEII0139 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Bme Brucella melitensis Length = 269 Score = 100 bits (248), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 52/148 (35%), Positives = 85/148 (57%), Gaps = 1/148 (0%) Query: 1 MRFPPQGARGF-AAMHRASRYGTWSEFGRRANEAVSCIVQLETPDAIARLEEIAAVPGVD 59 MR+PP G RG +A+ RAS + ++ + AN+ V ++Q+E+ +A L+ IA GVD Sbjct: 111 MRYPPHGVRGVGSALARASAFNRIPDYLQTANDEVCLLLQVESRAGLANLDAIATTEGVD 170 Query: 60 ALFLGPGDLSAAMGKIGNLADAEVRAAIADVAQRARAVGKPVGIVGPTPAMVREFVAMGY 119 +F+GP DL+A MG +G EV+ A+ D QR GK GI+ ++ R ++ +G Sbjct: 171 GVFIGPADLAADMGHLGKPGAQEVQDAVRDALQRIIGHGKAAGILTGDLSLARHYLDLGA 230 Query: 120 DYVAIASDMGMMMRQANAFIAEFDQTAP 147 +VAI +D+ ++ +A+F T P Sbjct: 231 TFVAIGNDVTLLANATTRLLADFKTTEP 258