BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0090.p (429 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5025 [E] COG2873 O-acetylhomoserine sulfhydrylase Pae Pseudomo... 630 e-180 BH2603 [E] COG2873 O-acetylhomoserine sulfhydrylase Bha Bacillus... 483 e-136 SMc01809 [E] COG2873 O-acetylhomoserine sulfhydrylase Sme Sinorh... 481 e-135 AGc2311 [E] COG2873 O-acetylhomoserine sulfhydrylase Atu Agrobac... 477 e-134 MA2715 [E] COG2873 O-acetylhomoserine sulfhydrylase Mac Methanos... 476 e-134 lin0604 [E] COG2873 O-acetylhomoserine sulfhydrylase Lin Listeri... 475 e-134 mlr8465 Non COG 469 e-132 TM0882 [E] COG2873 O-acetylhomoserine sulfhydrylase Tma Thermoto... 465 e-131 L75975 [E] COG2873 O-acetylhomoserine sulfhydrylase Lla Lactococ... 454 e-127 BMEI1166 [E] COG2873 O-acetylhomoserine sulfhydrylase Bme Brucel... 451 e-126 >PA5025 [E] COG2873 O-acetylhomoserine sulfhydrylase Pae Pseudomonas aeruginosa Length = 425 Score = 630 bits (1624), Expect = e-180, Method: Compositional matrix adjust. Identities = 299/411 (72%), Positives = 346/411 (84%) Query: 8 KFETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPTQD 67 K ET++VH GY PDPTTRAVAVPIYQT ++AFDDTQHGADLFDLKV GNIY+RIMNPT D Sbjct: 2 KLETLAVHAGYSPDPTTRAVAVPIYQTTSYAFDDTQHGADLFDLKVPGNIYTRIMNPTND 61 Query: 68 VLEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAHTLPQY 127 VLE+R+AALEGG+GALA+ASG AA+TYAIQT+AEAGDNIVS + LYGGTYNL AHTLP+ Sbjct: 62 VLEQRVAALEGGVGALAVASGMAAITYAIQTVAEAGDNIVSVAKLYGGTYNLLAHTLPRI 121 Query: 128 GVQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGVPLIVDNT 187 G+Q RFA A+ E LID+RTKA++ E+IGNP GNI D+ A+AD AHRHGVPLIVDNT Sbjct: 122 GIQARFAAHDDVAALEALIDERTKAVFCETIGNPAGNIIDLQALADAAHRHGVPLIVDNT 181 Query: 188 VATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKRLNEPDVS 247 VATP L RPFEHGADIVVHSLTKY+GGHGT++GG +VDSGKF WA +K RF LN PD S Sbjct: 182 VATPVLCRPFEHGADIVVHSLTKYMGGHGTSIGGIVVDSGKFDWAANKSRFPLLNTPDPS 241 Query: 248 YHGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRITANTLAV 307 YHGV YTEA G AA+IGR RVVPLRNMGAALSPFNAF ILQG+ETL LR++R N LAV Sbjct: 242 YHGVTYTEAFGPAAFIGRCRVVPLRNMGAALSPFNAFLILQGLETLALRMERHCDNALAV 301 Query: 308 AQYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARFQDALQLF 367 A+YL++HP+V WV YAGL D+P+HALA+ Y GR + +L+FG+ G GARF DAL+L Sbjct: 302 ARYLQQHPQVAWVKYAGLADNPEHALARRYLGGRPAAILSFGIQGGSAAGARFIDALKLV 361 Query: 368 TRLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDL 418 RLVNIGDAKSLA HPASTTHRQL+ EL +AGV++D VRLSIGIEHIDD+ Sbjct: 362 VRLVNIGDAKSLACHPASTTHRQLNAEELARAGVSDDMVRLSIGIEHIDDI 412 >BH2603 [E] COG2873 O-acetylhomoserine sulfhydrylase Bha Bacillus halodurans Length = 430 Score = 483 bits (1243), Expect = e-136, Method: Compositional matrix adjust. Identities = 245/429 (57%), Positives = 314/429 (73%), Gaps = 1/429 (0%) Query: 1 MADNPQWKFETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSR 60 M QW+ ET +VH G + DPTT + AVP+YQT ++ F DT H A+LF L GNIY+R Sbjct: 1 MNHENQWQLETKAVHSGQEIDPTTLSRAVPLYQTTSYGFKDTDHAANLFSLSEFGNIYTR 60 Query: 61 IMNPTQDVLEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLF 120 +MNPT DV EKR+AALEGG ALA ASGQAA+TY+I IAEAGD IVSAS+LYGGTYNLF Sbjct: 61 LMNPTTDVFEKRVAALEGGAAALATASGQAAITYSILNIAEAGDEIVSASSLYGGTYNLF 120 Query: 121 AHTLPQYGVQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGV 180 + TLP+ GV RF DP P +F+ I ++TKAI+ ESIGNP G++ DI AVA +AH H + Sbjct: 121 SITLPKLGVNVRFVDPSDPENFKAAITEKTKAIFAESIGNPKGDVLDIEAVAKVAHDHHL 180 Query: 181 PLIVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKR 240 PLIVDNT +PYLL+P +HGADIVVHS TK++GGHGT++GG IVD G F WAK R+ Sbjct: 181 PLIVDNTFPSPYLLQPIKHGADIVVHSATKFIGGHGTSIGGIIVDGGTFDWAK-TDRYPG 239 Query: 241 LNEPDVSYHGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRI 300 L PD SYHGVVYT+A+G AYI +ARV LR+MGAA+SPFN+F +LQG+ETL LR++R Sbjct: 240 LTTPDPSYHGVVYTDAVGPIAYIIKARVQLLRDMGAAISPFNSFLLLQGLETLHLRMERH 299 Query: 301 TANTLAVAQYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARF 360 + N VA++L++H V V+Y+GL HP + LA+ Y +LTF V G E G + Sbjct: 300 SENAYKVAEFLEQHQAVESVSYSGLPSHPSYPLAKKYLPKGQGAILTFEVKGGVEAGKKL 359 Query: 361 QDALQLFTRLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLA 420 ++QLF+ L N+GD+KSL HPASTTH+QLS E AGVT +RLS+G E I D++ Sbjct: 360 IHSVQLFSHLANVGDSKSLIIHPASTTHQQLSEAEQRDAGVTPGMIRLSVGTESIHDIIT 419 Query: 421 DLEQALQSA 429 DL+QA++++ Sbjct: 420 DLKQAIEAS 428 >SMc01809 [E] COG2873 O-acetylhomoserine sulfhydrylase Sme Sinorhizobium meliloti Length = 426 Score = 481 bits (1238), Expect = e-135, Method: Compositional matrix adjust. Identities = 239/421 (56%), Positives = 296/421 (70%), Gaps = 1/421 (0%) Query: 9 FETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPTQDV 68 F T+++H G PDPTT A A PIYQT +F F+DT H A LF L+ GNIY+RIMNPTQ V Sbjct: 7 FSTLAIHAGAQPDPTTGARATPIYQTTSFVFNDTDHAAALFGLQQFGNIYTRIMNPTQAV 66 Query: 69 LEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAHTLPQYG 128 LE+R+AALEGG LA++SG AA TI GDN VSA LYGG+ N F H + Sbjct: 67 LEERIAALEGGTAGLAVSSGHAAQLLVFHTIMRPGDNFVSARQLYGGSANQFGHAFKAFD 126 Query: 129 VQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGVPLIVDNTV 188 Q R+AD +P SF+ ID+RTKAI+IES+ NP G DIAA+AD+A RHG+PLIVDNT+ Sbjct: 127 WQVRWADSAEPESFDAQIDERTKAIFIESLANPGGTFVDIAAIADVARRHGLPLIVDNTM 186 Query: 189 ATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKRLNEPDVSY 248 ATPYL+RP EHGADIVVHSLTK++GGHG ++GG IVD G F W+K ++ L+EP Y Sbjct: 187 ATPYLMRPLEHGADIVVHSLTKFIGGHGNSMGGIIVDGGTFDWSK-SGKYPLLSEPRPEY 245 Query: 249 HGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRITANTLAVA 308 GVV +A G A+ ARV+ LR+ G A+SPFNAF I G+ETL LR+ R N L VA Sbjct: 246 GGVVLHQAFGNFAFAIAARVLGLRDFGPAISPFNAFLIQTGVETLPLRMQRHCDNALEVA 305 Query: 309 QYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARFQDALQLFT 368 ++LK H KV WV Y+GLED P+HAL + Y A V TFG+A G E G RF +AL++F+ Sbjct: 306 KWLKGHEKVSWVRYSGLEDDPNHALQKRYSPKGAGAVFTFGLAGGYEAGKRFVEALEMFS 365 Query: 369 RLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLADLEQALQS 428 L NIGD +SL HPASTTHRQL+P + AG D +RLS+GIE + D++ADLEQAL Sbjct: 366 HLANIGDTRSLVIHPASTTHRQLTPEQQVAAGAGPDVIRLSVGIEDVADIIADLEQALGK 425 Query: 429 A 429 A Sbjct: 426 A 426 >AGc2311 [E] COG2873 O-acetylhomoserine sulfhydrylase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 427 Score = 477 bits (1227), Expect = e-134, Method: Compositional matrix adjust. Identities = 241/425 (56%), Positives = 297/425 (69%), Gaps = 3/425 (0%) Query: 2 ADNPQWKFETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRI 61 ++NP F T++VH G PDPTT A A PIYQT A+AF D H A LF LK GNIY+RI Sbjct: 3 SNNP--GFSTLAVHAGAQPDPTTGARATPIYQTTAYAFRDADHAAALFGLKEFGNIYTRI 60 Query: 62 MNPTQDVLEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFA 121 MNPTQ VLE+R+AALEGG ALA+ASG AA T+ ++GDN V+A LYGG+ N F Sbjct: 61 MNPTQAVLEERVAALEGGTAALAVASGHAAQLLVFHTLMQSGDNFVAARQLYGGSINQFG 120 Query: 122 HTLPQYGVQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGVP 181 H + Q R+AD PASFE I++RT+AI+IES+ NP G DIAA+AD+AHRHG+P Sbjct: 121 HAFKGFDWQVRWADAADPASFEAQINERTRAIFIESLANPGGTFVDIAAIADVAHRHGLP 180 Query: 182 LIVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKRL 241 LIVDNT+A+PYLLRP EHGADIV+HSLTK+LGGHG ++GG IVD G F W+ RF L Sbjct: 181 LIVDNTMASPYLLRPLEHGADIVLHSLTKFLGGHGNSMGGIIVDGGTFDWSA-TDRFPAL 239 Query: 242 NEPDVSYHGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRIT 301 ++P Y GV+ + G A+ RV+ LR++G A+SPFNAF IL GIETL LR+ R + Sbjct: 240 SQPRPEYSGVLLHQTFGNFAFAIACRVLGLRDLGPAISPFNAFLILTGIETLPLRVQRHS 299 Query: 302 ANTLAVAQYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARFQ 361 N LAVA++LK HPKV WV+YAGLED +HA+ Q Y A V TFGV G G Sbjct: 300 DNALAVAKWLKAHPKVGWVHYAGLEDSDNHAIQQHYSPKGAGSVFTFGVKGGYAAGKALV 359 Query: 362 DALQLFTRLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLAD 421 + LQLF+ L NIGD +SL HPASTTH QL+P + AG D VRLSIGIE + D++AD Sbjct: 360 EGLQLFSHLANIGDTRSLVIHPASTTHAQLTPEQQTAAGAGPDVVRLSIGIEDVKDIIAD 419 Query: 422 LEQAL 426 LEQ+ Sbjct: 420 LEQSF 424 >MA2715 [E] COG2873 O-acetylhomoserine sulfhydrylase Mac Methanosarcina acetivorans str.C2A Length = 441 Score = 476 bits (1226), Expect = e-134, Method: Compositional matrix adjust. Identities = 233/425 (54%), Positives = 297/425 (69%), Gaps = 5/425 (1%) Query: 3 DNPQWKFETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIM 62 +NP T++VH G PDP T A +VPIYQT A+ FDDT+H ADLF L+ +GNIY+R+M Sbjct: 20 ENPG--ISTLAVHAGAKPDPVTGARSVPIYQTAAYVFDDTEHAADLFGLRKEGNIYTRLM 77 Query: 63 NPTQDVLEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAH 122 NPT DV EKR+AALEGGIGALA +SG AA+T A+ T GD IVS +YGGTY LF + Sbjct: 78 NPTTDVFEKRIAALEGGIGALATSSGMAAITTALLTFTGPGDEIVSGDKIYGGTYELFNY 137 Query: 123 TLPQYGVQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGVPL 182 T P+ G +F D P F+ I +TKA+Y+ESIGNP ++ D +A+IAH +PL Sbjct: 138 TFPKLGRTVKFVDSSSPEEFKKEITGKTKALYVESIGNPKLDVPDFEKLAEIAHTAEIPL 197 Query: 183 IVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKRLN 242 +VDNTVA P +LRP EHGADIVVHS TKY+GGHGT++GG I+DSG F W+ ++F + Sbjct: 198 VVDNTVA-PVILRPIEHGADIVVHSATKYIGGHGTSIGGVIIDSGNFDWS--SEKFPEIC 254 Query: 243 EPDVSYHGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRITA 302 +PD YHG+ Y EA G+AA+I +ARV +R++GA LSPFN+F G+ETL LR+ + Sbjct: 255 DPDPGYHGLKYKEAFGKAAFIAKARVQFMRDIGACLSPFNSFLFTLGLETLPLRVKKHCD 314 Query: 303 NTLAVAQYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARFQD 362 N LAVA++L+ HPKV WV+Y GLE H H LA+ Y K ++ FG+ G E +F + Sbjct: 315 NALAVARFLQAHPKVAWVSYPGLESHRSHELAKKYLKSGYGAIIGFGIKGGTEATKKFVE 374 Query: 363 ALQLFTRLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLADL 422 +L+LF+ L NIGDAKSL HPASTTH QLS E GVTED +RLSIGIE DL+ DL Sbjct: 375 SLELFSHLANIGDAKSLVIHPASTTHEQLSAEEQRACGVTEDFIRLSIGIEDEKDLIFDL 434 Query: 423 EQALQ 427 QAL Sbjct: 435 GQALS 439 >lin0604 [E] COG2873 O-acetylhomoserine sulfhydrylase Lin Listeria innocua Length = 425 Score = 475 bits (1222), Expect = e-134, Method: Compositional matrix adjust. Identities = 235/422 (55%), Positives = 303/422 (71%), Gaps = 2/422 (0%) Query: 6 QWKFETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPT 65 ++KFETI VHGG+ PD T + AVPIYQT ++ FD +H A LF L+ GNIY+RIMNPT Sbjct: 4 EYKFETIQVHGGHTPDGDTHSRAVPIYQTTSYTFDSPEHAAALFGLQETGNIYTRIMNPT 63 Query: 66 QDVLEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAHTLP 125 VLE+RL LEGGIGA+A ASG AA+TY+I IA +GD+IV+A+TLYGGT+ LF+HT Sbjct: 64 TAVLEERLTLLEGGIGAVATASGMAAITYSILNIAGSGDHIVAAATLYGGTHTLFSHTFK 123 Query: 126 QYGVQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGVPLIVD 185 +G+ F DP +P +FE + + TKA++IE+IGNP NI DI VA+IAH VPLIVD Sbjct: 124 TFGIDVTFVDPNEPENFEKAMKENTKAVFIETIGNPDINIIDIEKVAEIAHASDVPLIVD 183 Query: 186 NTVATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKRLNEPD 245 NT AT YL RPF+ GADIVV+S TK++GGHG +GGA++DSGKF WA K F +L PD Sbjct: 184 NTFATAYLNRPFDFGADIVVYSATKFIGGHGVAIGGAVIDSGKFNWANGK--FPKLVVPD 241 Query: 246 VSYHGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRITANTL 305 SY+G+ YT +G AAYI + RV LR+ GAALSPFNAF ++ G+ETL LRL++ N Sbjct: 242 DSYNGLSYTNDVGAAAYITKLRVSLLRDTGAALSPFNAFLLILGLETLSLRLEQHVKNAK 301 Query: 306 AVAQYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARFQDALQ 365 VA +L HPKV WVNY GL+D+ H LAQ Y + TFGV G G + ++++ Sbjct: 302 QVANFLNDHPKVAWVNYPGLKDNKYHDLAQKYLPKGPGSIFTFGVKGGYAAGKKVIESVE 361 Query: 366 LFTRLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLADLEQA 425 LF+ L N+GDAKSL HPASTTH+QLS + AGV +++RLSIGIE+ DD++ DL +A Sbjct: 362 LFSHLANVGDAKSLIIHPASTTHQQLSEEQQLTAGVKPESIRLSIGIENADDIIQDLTKA 421 Query: 426 LQ 427 L+ Sbjct: 422 LE 423 >mlr8465 Non COG Length = 426 Score = 469 bits (1207), Expect = e-132, Method: Compositional matrix adjust. Identities = 234/418 (55%), Positives = 289/418 (69%), Gaps = 1/418 (0%) Query: 9 FETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPTQDV 68 F T++VH G PDP T A A PIYQT +F FDD H A LF LK GNIY+RIMNPTQ V Sbjct: 7 FNTLAVHAGAKPDPATGARATPIYQTTSFVFDDADHAASLFGLKAFGNIYTRIMNPTQAV 66 Query: 69 LEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAHTLPQYG 128 LE+R+AALEGG ALA+ASG AA + + GDN V+A+ LYGG+ N F H YG Sbjct: 67 LEERVAALEGGTAALAVASGHAAQVIVFHNLMQPGDNFVAATRLYGGSINQFGHAFKNYG 126 Query: 129 VQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGVPLIVDNTV 188 + R+AD ++FE IDDRTKAI+IES+ NP G DI + DIA +HG+PLIVDNT+ Sbjct: 127 WEVRWADTNDLSTFESQIDDRTKAIFIESLANPGGTFVDIEKIGDIARKHGLPLIVDNTL 186 Query: 189 ATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKRLNEPDVSY 248 A+PYL+RP EHGADIVVHSLTK++GGHG ++GG IVD G F W+K ++ L+EP Y Sbjct: 187 ASPYLIRPIEHGADIVVHSLTKFIGGHGNSIGGVIVDGGTFDWSK-SGKYPMLSEPRPEY 245 Query: 249 HGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRITANTLAVA 308 G+V E G A+ ARV+ LR++G A+SPFNAF IL G+ETL LR+ R N + VA Sbjct: 246 GGLVLHETFGNFAFAIAARVLGLRDLGPAISPFNAFLILTGLETLPLRMQRHCDNAVTVA 305 Query: 309 QYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARFQDALQLFT 368 +L HPKV WVNY GL ++AL + Y A V TFG+ G E G +F +AL+LF+ Sbjct: 306 GWLSNHPKVAWVNYPGLPSDKNNALQKKYSPLGAGAVFTFGLKGGYEAGVKFVEALELFS 365 Query: 369 RLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLADLEQAL 426 L N+GD KSL HPASTTHRQLS + KAG DTVRLSIGIE + D++ADLEQAL Sbjct: 366 HLANVGDTKSLVIHPASTTHRQLSDEQKVKAGAGPDTVRLSIGIEDVTDIVADLEQAL 423 >TM0882 [E] COG2873 O-acetylhomoserine sulfhydrylase Tma Thermotoga maritima Length = 430 Score = 465 bits (1197), Expect = e-131, Method: Compositional matrix adjust. Identities = 233/429 (54%), Positives = 301/429 (70%), Gaps = 5/429 (1%) Query: 3 DNPQWKFETISVHGGYDP-DPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRI 61 D ++ + T ++H GY+P + T + AVPIYQT ++ F D+ H A LF L+ G IY+RI Sbjct: 2 DWKKYGYNTRALHAGYEPPEQATGSRAVPIYQTTSYVFRDSDHAARLFALEEPGFIYTRI 61 Query: 62 MNPTQDVLEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFA 121 NPT VLE+R+AALE G+GALA+ASGQAA+TYAI IA GD IVS S LYGGTYNLF Sbjct: 62 GNPTVSVLEERIAALEEGVGALAVASGQAAITYAILNIAGPGDEIVSGSALYGGTYNLFR 121 Query: 122 HTL-PQYGVQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGV 180 HTL + G+ +F D P + E I ++TKA+Y+E+IGNP + D A+A+IAHRHGV Sbjct: 122 HTLYKKSGIIVKFVDETDPKNIEEAITEKTKAVYLETIGNPGLTVPDFEAIAEIAHRHGV 181 Query: 181 PLIVDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKR 240 PLIVDNTVA PY+ RPFEHGADIVV+S TK++GGHGT++GG IVDSGKF W K F Sbjct: 182 PLIVDNTVA-PYIFRPFEHGADIVVYSATKFIGGHGTSIGGLIVDSGKFDWTNGK--FPE 238 Query: 241 LNEPDVSYHGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRI 300 L EPD SYHGV Y E EAAYI + R LR++G+ +SPFNAF + G+ETL LR+ + Sbjct: 239 LVEPDPSYHGVSYVETFKEAAYIAKCRTQLLRDLGSCMSPFNAFLFILGLETLSLRMKKH 298 Query: 301 TANTLAVAQYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARF 360 N L + ++LK HP V WVNY E + A Y K ++TFGV G+E G +F Sbjct: 299 CENALKIVEFLKSHPAVSWVNYPIAEGNKTRENALKYLKEGYGAIVTFGVKGGKEAGKKF 358 Query: 361 QDALQLFTRLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLA 420 D+L L + L NIGDA++LA HPASTTH+QL+ E K GVT D +RLS+GIE ++D++A Sbjct: 359 IDSLTLISHLANIGDARTLAIHPASTTHQQLTEEEQLKTGVTPDMIRLSVGIEDVEDIIA 418 Query: 421 DLEQALQSA 429 DL+QAL+ + Sbjct: 419 DLDQALRKS 427 >L75975 [E] COG2873 O-acetylhomoserine sulfhydrylase Lla Lactococcus lactis Length = 426 Score = 454 bits (1169), Expect = e-127, Method: Compositional matrix adjust. Identities = 222/425 (52%), Positives = 298/425 (70%), Gaps = 4/425 (0%) Query: 4 NPQWKFETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMN 63 N +KF+T+ VH G PDP T + AVP+YQT +F F+++ H F L+ G IYSR+ N Sbjct: 3 NHNYKFDTLQVHAGQVPDPVTGSRAVPLYQTTSFVFNNSDHAEARFALQDPGAIYSRLGN 62 Query: 64 PTQDVLEKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAHT 123 PT DV E R+AALEGG AL + SG AA+TYAI IA GDNIVSASTLYGGTY+LF+ T Sbjct: 63 PTNDVFEARIAALEGGSAALGVGSGSAAITYAILNIATVGDNIVSASTLYGGTYHLFSGT 122 Query: 124 LPQYGVQTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGVPLI 183 LP+YG+ T+F +P P +FE ID++TKAIY E++GNP N+ D A+ IA +HG+P+I Sbjct: 123 LPKYGITTKFVNPDDPKNFEEAIDEKTKAIYYETLGNPGNNVIDYDAIGQIAKKHGIPVI 182 Query: 184 VDNTVATPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKRLNE 243 VD T TP +PFEHGA+++VHS TK++GGHGT++GG IVD G F WA F + Sbjct: 183 VDATFTTPVTFKPFEHGANVIVHSATKFIGGHGTSIGGVIVDGGNFDWA--NGNFPDFTQ 240 Query: 244 PDVSYHGVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRITAN 303 D SY+G+ + E LGE A++ R R + LR+ GAALSPF+++ LQG+ETL LR++R +N Sbjct: 241 ADESYNGIKFAE-LGEIAFVTRVRAILLRDTGAALSPFHSWLFLQGLETLSLRVERHISN 299 Query: 304 TLAVAQYLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGAR-FQD 362 T + ++L HPKV VN+ LE + HAL Q Y+ A + TF + + E AR D Sbjct: 300 TKKIVEFLDNHPKVELVNHPLLESNSYHALYQKYYPKDAGSIFTFELKDKDEKKARDLID 359 Query: 363 ALQLFTRLVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLADL 422 L++F+ L N+GD KSLA HPASTTH+QL+ EL AG+++ T+RLS+GIE + DL+ADL Sbjct: 360 HLEIFSLLANVGDTKSLAIHPASTTHQQLNAEELASAGISKGTIRLSVGIEDVTDLIADL 419 Query: 423 EQALQ 427 EQAL+ Sbjct: 420 EQALE 424 >BMEI1166 [E] COG2873 O-acetylhomoserine sulfhydrylase Bme Brucella melitensis Length = 434 Score = 451 bits (1161), Expect = e-126, Method: Compositional matrix adjust. Identities = 229/420 (54%), Positives = 284/420 (67%), Gaps = 1/420 (0%) Query: 10 ETISVHGGYDPDPTTRAVAVPIYQTVAFAFDDTQHGADLFDLKVQGNIYSRIMNPTQDVL 69 ET++VH G PDP T A A PIYQT +F F+D H A LF L+ GNIY+RI NPT VL Sbjct: 16 ETLAVHAGAKPDPATGARATPIYQTTSFVFEDADHAAALFGLQAFGNIYTRITNPTTAVL 75 Query: 70 EKRLAALEGGIGALALASGQAAVTYAIQTIAEAGDNIVSASTLYGGTYNLFAHTLPQYGV 129 E+R+AALEGG A+A ASG AA A T+ + GDN ++A LYGG+ N F + + Sbjct: 76 EERIAALEGGTAAVATASGHAAQFLAFHTLLQPGDNFIAARQLYGGSINQFGQSFKSFDW 135 Query: 130 QTRFADPRQPASFEPLIDDRTKAIYIESIGNPLGNITDIAAVADIAHRHGVPLIVDNTVA 189 Q R+AD PA F ID+RT+AI+IES NP G + DI A+A+IAHR+G+PLIVDNT+A Sbjct: 136 QVRWADATNPADFAKQIDERTRAIFIESFANPGGIVVDIEAIAEIAHRNGLPLIVDNTLA 195 Query: 190 TPYLLRPFEHGADIVVHSLTKYLGGHGTTLGGAIVDSGKFPWAKHKQRFKRLNEPDVSYH 249 +PYL+RP EHGADIVVHSLTK++GGHG ++GG +VD G F WAK + L EP Y Sbjct: 196 SPYLVRPIEHGADIVVHSLTKFIGGHGNSMGGILVDGGTFDWAK-SGNYPLLTEPRPDYA 254 Query: 250 GVVYTEALGEAAYIGRARVVPLRNMGAALSPFNAFQILQGIETLGLRLDRITANTLAVAQ 309 G+ + G ++ ARV+ LR+ G A+SPFNAFQIL G+ETL LR+ R + N L VA Sbjct: 255 GLELHKTFGNISFAIAARVLGLRDFGPAISPFNAFQILTGVETLALRMQRHSDNALKVAT 314 Query: 310 YLKRHPKVRWVNYAGLEDHPDHALAQTYFKGRASGVLTFGVANGREGGARFQDALQLFTR 369 +L H KV WVNYAGL HAL Q Y A V TFG+ G E G +F D+L+LF+ Sbjct: 315 WLHGHEKVSWVNYAGLPHDKYHALQQKYAPKGAGSVFTFGIKGGYEAGVKFVDSLELFSL 374 Query: 370 LVNIGDAKSLATHPASTTHRQLSPTELEKAGVTEDTVRLSIGIEHIDDLLADLEQALQSA 429 L N+GD +SL HPASTTHRQLS + AG D VRLSIGIE DD++ADLEQAL A Sbjct: 375 LANLGDTRSLVIHPASTTHRQLSDEQKVAAGAGPDVVRLSIGIEDADDIIADLEQALAKA 434