BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0073.p (204 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0714 [H] COG0307 Riboflavin synthase alpha chain Rso Ralstoni... 281 9e-76 PA4055 [H] COG0307 Riboflavin synthase alpha chain Pae Pseudomon... 184 8e-47 VC2270 [H] COG0307 Riboflavin synthase alpha chain Vch Vibrio ch... 176 2e-44 DR0154 [H] COG0307 Riboflavin synthase alpha chain Dra Deinococc... 163 2e-40 XF0952 [H] COG0307 Riboflavin synthase alpha chain Xfa Xylella f... 158 7e-39 aq_1707 [H] COG0307 Riboflavin synthase alpha chain Aae Aquifex ... 150 2e-36 mlr8407 [H] COG0307 Riboflavin synthase alpha chain Mlo Mesorhiz... 150 2e-36 all5258 [H] COG0307 Riboflavin synthase alpha chain Nos Nostoc s... 149 4e-36 SP0177 [H] COG0307 Riboflavin synthase alpha chain Spn Streptoco... 145 6e-35 BH1555 [H] COG0307 Riboflavin synthase alpha chain Bha Bacillus ... 144 2e-34 >RSc0714 [H] COG0307 Riboflavin synthase alpha chain Rso Ralstonia solanacearum Length = 217 Score = 281 bits (718), Expect = 9e-76, Method: Compositional matrix adjust. Identities = 146/201 (72%), Positives = 156/201 (77%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVEKTA 60 MFTGIVAAIG I +V PLAA AGVRL I AG LP+ADV LGDSIA+ GACMTVV K Sbjct: 1 MFTGIVAAIGRIETVEPLAADAQAGVRLGIHAGGLPLADVALGDSIAIQGACMTVVAKND 60 Query: 61 NGFTVDVSRESLRLTAGLDAPGEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEPVGES 120 F VDVSRESL T GLD PGEVNLEKAL LA+ +GGHLVSGHVDGLG V F PVGES Sbjct: 61 THFDVDVSRESLSKTVGLDRPGEVNLEKALRLADHIGGHLVSGHVDGLGTVSHFAPVGES 120 Query: 121 RELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEVTTLKHLK 180 EL V LG+Y AYKGS+VVNGVSLTVN V D A C FSINLIPHT+ VTTLKHL Sbjct: 121 YELRVRTSPELGRYFAYKGSVVVNGVSLTVNSVRDDATGCEFSINLIPHTLAVTTLKHLA 180 Query: 181 AGSKVNLEIDLIARYVERMLS 201 G +VNLEIDLIARYVERML+ Sbjct: 181 VGGQVNLEIDLIARYVERMLT 201 >PA4055 [H] COG0307 Riboflavin synthase alpha chain Pae Pseudomonas aeruginosa Length = 219 Score = 184 bits (468), Expect = 8e-47, Method: Compositional matrix adjust. Identities = 102/206 (49%), Positives = 134/206 (65%), Gaps = 10/206 (4%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVEKTA 60 MFTGI+ +IG++ ++TP G D +R+ I G L + DV LGDSIA+NG C+T VE Sbjct: 1 MFTGIIESIGSVRAMTP--KGGD--LRVYIATGKLDLGDVKLGDSIAVNGVCLTAVELPG 56 Query: 61 NGFTVDVSRESLRLTA--GLDAPGEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEPVG 118 +GF DVSRESL TA L VNLEKALT RLGGHLVSGHVDG+G+V E Sbjct: 57 DGFWADVSRESLARTAFQHLKVGSRVNLEKALTPTTRLGGHLVSGHVDGVGEVLKREENA 116 Query: 119 ESRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEVTTLKH 178 + + V AP+ L +Y+A+KGSI V+G SLTVN V F + ++PHT+ T + Sbjct: 117 RAIQFTVRAPRELARYIAHKGSITVDGTSLTVNAV----NGAEFELTIVPHTLSETIMAE 172 Query: 179 LKAGSKVNLEIDLIARYVERMLSASK 204 + G +VNLE+DL+ARY+ER+L K Sbjct: 173 YQPGRRVNLEVDLLARYLERLLLGDK 198 >VC2270 [H] COG0307 Riboflavin synthase alpha chain Vch Vibrio cholerae Length = 217 Score = 176 bits (447), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 94/206 (45%), Positives = 132/206 (64%), Gaps = 10/206 (4%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVEKTA 60 MFTGIV A+G +T++ P G D V +++D G L M DV LGDSIA NG C+TVV Sbjct: 1 MFTGIVEAVGKLTAIIP--KGSD--VTISVDVGKLDMGDVKLGDSIATNGVCLTVVAFDQ 56 Query: 61 NGFTVDVSRESLRLT--AGLDAPGEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEPVG 118 F+ D+S E+L+ + A VNLEKA+ R GGH+VSGHVDG+G++ PVG Sbjct: 57 RSFSADLSMETLKKSGFAQYQVGDRVNLEKAMLPTTRFGGHIVSGHVDGVGEIVERIPVG 116 Query: 119 ESRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEVTTLKH 178 + +L V+ P + KY+A KGSI V+G+SLTVN + A F + ++PHT TT+ Sbjct: 117 RAVDLWVNMPAEISKYVAEKGSITVDGISLTVNDLRKNA----FKLTIVPHTSAETTIDE 172 Query: 179 LKAGSKVNLEIDLIARYVERMLSASK 204 + G +VNLE+D++ARY+ER+L + Sbjct: 173 FQVGRRVNLEVDVLARYMERLLQGQQ 198 >DR0154 [H] COG0307 Riboflavin synthase alpha chain Dra Deinococcus radiodurans Length = 214 Score = 163 bits (413), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 97/208 (46%), Positives = 133/208 (63%), Gaps = 12/208 (5%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVEKTA 60 MFTGI+ IG +T AA + + +TI A + AD+ LG+SIA G C+TV Sbjct: 1 MFTGIIEQIGRVTH----AAEQNGNLAVTI-APTQMWADLVLGESIACGGTCLTVTGWDE 55 Query: 61 NGFTVDVSRESLRLTA-GLDAPGEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEPVGE 119 F VD+SRE+L TA +A EVNLE+A+T R GGH+VSGHVDG+G+V Sbjct: 56 QSFCVDLSRETLAKTAPHWEAGQEVNLERAMTAQARFGGHIVSGHVDGVGEVLEVREEPG 115 Query: 120 SRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEAC------RFSINLIPHTVEV 173 + + V AP++L KYL KGS+ V+GVSLT+ V A + F++ L+PHT+EV Sbjct: 116 AYTMRVRAPRSLAKYLTPKGSVTVDGVSLTLVDVGGPAGSRPEWPLDEFTLWLVPHTLEV 175 Query: 174 TTLKHLKAGSKVNLEIDLIARYVERMLS 201 TTLKH +AG++VNLE D +A+YVER+L+ Sbjct: 176 TTLKHWRAGTRVNLEADQVAKYVERLLA 203 >XF0952 [H] COG0307 Riboflavin synthase alpha chain Xfa Xylella fastidiosa 9a5c Length = 200 Score = 158 bits (400), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 97/202 (48%), Positives = 122/202 (60%), Gaps = 10/202 (4%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVEKTA 60 MFTGI+ +G + + + G D VR T + G+LP ++V G+SIA+NG C+TV A Sbjct: 1 MFTGIIGGVGRLAA--RVRQGGD--VRFTFEVGTLPFSEVSYGESIAVNGVCLTVTAFDA 56 Query: 61 NGFTVDVSRESLRLTAGLDAP--GEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEPVG 118 F D S E+L LT P +NLE+A+ +RLGGHLVSGHVDG+G+V S Sbjct: 57 LCFQADASTETLALTTLGQLPEGATLNLERAMCPTDRLGGHLVSGHVDGIGRVLSVHEDA 116 Query: 119 ESRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEVTTLKH 178 ++ P L KY+A KGSI V+GVSLTVN V AE F + LIPHTV T Sbjct: 117 RAQRWSFAVPVPLLKYVAKKGSICVDGVSLTVNAVN--AEG--FEVALIPHTVAHTRFSR 172 Query: 179 LKAGSKVNLEIDLIARYVERML 200 G VNLEIDLIARYVER+L Sbjct: 173 TVIGEAVNLEIDLIARYVERLL 194 >aq_1707 [H] COG0307 Riboflavin synthase alpha chain Aae Aquifex aeolicus Length = 207 Score = 150 bits (378), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 84/206 (40%), Positives = 127/206 (61%), Gaps = 13/206 (6%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVEKTA 60 MFTG+V +G + ++T G +L+++ + DV LGDS+++NGAC+TVV+ + Sbjct: 1 MFTGLVEDLGKVKNLTL----SSKGAKLSVET---KLEDVKLGDSVSVNGACLTVVDIKS 53 Query: 61 NGFTVDVSRESLRLT--AGLDAPGEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEPVG 118 + T DVS E+L+ T L VNLE+AL + ERLGGH+V GHVD V SF +G Sbjct: 54 STLTFDVSPETLKRTNLGKLKTGDYVNLERALRVGERLGGHIVQGHVDFTAPVKSFNFLG 113 Query: 119 ESRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEVTTLKH 178 E EL+++ P+ Y+ KGSI ++G+SLTVN V++ + IN+IPHT + T L+ Sbjct: 114 EHYELVIEIPEEWSIYVVEKGSIALDGISLTVNYVKE----NKVFINIIPHTYKSTNLQF 169 Query: 179 LKAGSKVNLEIDLIARYVERMLSASK 204 K G +N+E D++ +YV L+ K Sbjct: 170 KKVGDLLNVETDILGKYVINYLNKLK 195 >mlr8407 [H] COG0307 Riboflavin synthase alpha chain Mlo Mesorhizobium loti Length = 205 Score = 150 bits (378), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 88/211 (41%), Positives = 126/211 (59%), Gaps = 16/211 (7%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVE--- 57 MFTGIV IGT+ +V PL+ G V L ID P + +G SI+ G C+TV Sbjct: 1 MFTGIVTDIGTVAAVRPLSEG----VGLRIDTAYDPET-IAIGASISCGGVCLTVTALPE 55 Query: 58 --KTANGFTVDVSRESLRLT--AGLDAPGEVNLEKALTLAERLGGHLVSGHVDGLGQVHS 113 A F V+ E+LRLT + + +VNLE+AL + + LGGH+VSGHVDG ++ Sbjct: 56 HGSNARWFEVEAWEEALRLTTASSWKSGSKVNLERALKIGDELGGHIVSGHVDGTAELVE 115 Query: 114 FEPVGESRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEV 173 + G++ ++AP+ L K++A KGS+ ++G SLTVN+V E RF + LI H++ V Sbjct: 116 RKDEGDAVRFTLEAPRHLAKFIAPKGSVALDGTSLTVNKV----EGTRFDVLLIHHSLTV 171 Query: 174 TTLKHLKAGSKVNLEIDLIARYVERMLSASK 204 TT K G +VN+EID +ARY R+ A+K Sbjct: 172 TTWGERKVGDRVNIEIDTMARYAARLAEAAK 202 >all5258 [H] COG0307 Riboflavin synthase alpha chain Nos Nostoc sp. PCC 7120 Length = 219 Score = 149 bits (376), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 91/208 (43%), Positives = 128/208 (61%), Gaps = 12/208 (5%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLP-MADVGLGDSIALNGACMTVVEKT 59 MFTG+V A+GTI PL G D+ ++T + SL M D+ GDS+A++G C+TV E Sbjct: 1 MFTGLVQALGTIK---PL--GGDSW-QITCVSQSLSIMQDLAYGDSVAVDGVCLTVEEIL 54 Query: 60 ANGFTVDVSRESLRLTA-GLDA--PGEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEP 116 +GF S E+LR T G + G VNLE +L + ++GGH V GHVDG+GQ+ FE Sbjct: 55 KDGFIASASPETLRRTTLGTEQTQQGYVNLETSLRVGGKVGGHFVMGHVDGVGQLLGFEQ 114 Query: 117 VGESRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEVTTL 176 S E+ AP+A+ +Y+ KGSI VNG+SLTV E E +F++ +IP T T L Sbjct: 115 TASSWEMTFTAPEAIARYIVPKGSITVNGISLTVAAYE--PELSQFTVAVIPLTYAETNL 172 Query: 177 KHLKAGSKVNLEIDLIARYVERMLSASK 204 ++L GS VNLE D++ +YVE+ L + Sbjct: 173 RYLVPGSLVNLEGDILGKYVEKFLQPGQ 200 >SP0177 [H] COG0307 Riboflavin synthase alpha chain Spn Streptococcus pneumoniae TIGR4 Length = 211 Score = 145 bits (366), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 81/205 (39%), Positives = 123/205 (60%), Gaps = 11/205 (5%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVEKTA 60 MFTGI+ IG + + +L+I A + + D+ LGDSIA+NG C+TV Sbjct: 1 MFTGIIEEIGKVERIQK----DSRNCKLSIKASKI-LTDIHLGDSIAVNGICLTVTHFNH 55 Query: 61 NGFTVDVSRESLRLTAG--LDAPGEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEPVG 118 FTVDV E+ TA L EVNLE+AL++ RLGGH+V+GH+DG G++ S + Sbjct: 56 QSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHIDGTGKISSIKKDD 115 Query: 119 ESRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEVTTLKH 178 + ++ K + + KGSI ++G+SLTV +V + FS+++IPHT+E T LK Sbjct: 116 NAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKV----NFSVSVIPHTLEQTILKS 171 Query: 179 LKAGSKVNLEIDLIARYVERMLSAS 203 + GS VNLE D++ +YV++++ S Sbjct: 172 KQVGSTVNLENDILGKYVQKLMDNS 196 >BH1555 [H] COG0307 Riboflavin synthase alpha chain Bha Bacillus halodurans Length = 215 Score = 144 bits (362), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 82/206 (39%), Positives = 123/206 (59%), Gaps = 11/206 (5%) Query: 1 MFTGIVAAIGTITSVTPLAAGPDAGVRLTIDAGSLPMADVGLGDSIALNGACMTVVEKTA 60 MFTGI+ +GTI ++ + +TI + + ++DV LGDSIA+NG C+TV T Sbjct: 1 MFTGIIEDVGTIDAIQQTGEA----IVMTITSKKI-VSDVQLGDSIAVNGVCLTVTSFTD 55 Query: 61 NGFTVDVSRESLRLTAG--LDAPGEVNLEKALTLAERLGGHLVSGHVDGLGQVHSFEPVG 118 FTVD+ E++R T+ L VNLE+A+ R GGH+VSGHVDG+G + E Sbjct: 56 TQFTVDLMPETVRATSLRLLSKGSRVNLERAMVANGRFGGHIVSGHVDGIGTIRKKERKD 115 Query: 119 ESRELIVDAPKALGKYLAYKGSIVVNGVSLTVNRVEDLAEACRFSINLIPHTVEVTTLKH 178 + ++ +L +Y+ +KGS+ V+G SLT+ V D F+I++IPHT+E T + Sbjct: 116 NAVYYTIEVSSSLRRYMIHKGSVAVDGTSLTIFDVSDKT----FTISIIPHTMEETIIGL 171 Query: 179 LKAGSKVNLEIDLIARYVERMLSASK 204 KAG VN+E DLI +Y+E+ + K Sbjct: 172 KKAGDIVNIECDLIGKYIEQFVQQGK 197