BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0032.p (268 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1352 [KT] COG3279 Response regulator of the LytR/AlgR family ... 246 3e-65 VCA0850 [KT] COG3279 Response regulator of the LytR/AlgR family ... 189 6e-48 XF1626 [KT] COG3279 Response regulator of the LytR/AlgR family X... 119 9e-27 PA5261 [KT] COG3279 Response regulator of the LytR/AlgR family P... 115 7e-26 BS_lytT [KT] COG3279 Response regulator of the LytR/AlgR family ... 102 7e-22 VC0693 [KT] COG3279 Response regulator of the LytR/AlgR family V... 97 3e-20 STM2158 [KT] COG3279 Response regulator of the LytR/AlgR family ... 96 8e-20 ypdB [KT] COG3279 Response regulator of the LytR/AlgR family Eco... 94 3e-19 Z3646 [KT] COG3279 Response regulator of the LytR/AlgR family Ec... 94 3e-19 ECs3261 [KT] COG3279 Response regulator of the LytR/AlgR family ... 94 3e-19 >RSc1352 [KT] COG3279 Response regulator of the LytR/AlgR family Rso Ralstonia solanacearum Length = 270 Score = 246 bits (628), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 145/268 (54%), Positives = 175/268 (65%), Gaps = 10/268 (3%) Query: 6 LIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEM-----ALESLPDVLFLDIRMP 60 LIA+DEP LA +L L WP +G AL+ A E+ PDV+FLDIRMP Sbjct: 8 LIADDEPALADSLIAELAALWPGARIAPAVHDGQSALDAIDRPRAGEA-PDVVFLDIRMP 66 Query: 61 GHSGLEVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQ 120 G SG+EVARELA R PL+VFVTAYD+ AL+AFE+AA+DY+LKPV ERL TV+ Sbjct: 67 GLSGIEVARELA----GRAQRPLVVFVTAYDQFALDAFEQAAVDYVLKPVQTERLAATVR 122 Query: 121 RLRALLAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEVIRAAVGNRTRLIPVE 180 RL A LA+R Q LAQL + ++ A A L I+A VG R IPVE Sbjct: 123 RLTARLAERPDGGAAADPAQTLAQLVERLAGLPAAGGANGAYLRFIKALVGQEIRFIPVE 182 Query: 181 EVIYFEATDKYVNVVTADGQALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVEAAVRDE 240 EV+Y EATDKYVNVVT G +LIRTSLREL+ QLDP FWQ+HRGTVV V V +AV Sbjct: 183 EVLYLEATDKYVNVVTHAGASLIRTSLRELLSQLDPQHFWQVHRGTVVNVAHVASAVHLS 242 Query: 241 AGKLSLQLRGRPERLAVSRLFAPLFRQM 268 G+L+L++RGR E L V+R +A LFRQM Sbjct: 243 LGRLALKIRGRTETLPVARQYAHLFRQM 270 >VCA0850 [KT] COG3279 Response regulator of the LytR/AlgR family Vch Vibrio cholerae Length = 261 Score = 189 bits (480), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 113/268 (42%), Positives = 159/268 (59%), Gaps = 20/268 (7%) Query: 4 SALIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEMALESLPDVLFLDIRMPGHS 63 +A++A+DEPLL L L WP LE A NG AL+ + PDV+FLDIRMP Sbjct: 7 TAVLADDEPLLRHHLNKLLAELWPALEIVASAENGQIALQAIEQHQPDVVFLDIRMPKMD 66 Query: 64 GLEVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQRLR 123 G+EVAR L +Q P+ PL+VF+TAYDE+A+ AFE AIDYLLKP++ RL ++L+ Sbjct: 67 GIEVARRLLQQ-PK---VPLVVFITAYDEYAVSAFETHAIDYLLKPLSSSRLASCCEKLQ 122 Query: 124 ALLAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEV-IRAAVGNRTRLIPVEEV 182 L + A S + L Q ++Q QL P + +V ++A+ G LI V E+ Sbjct: 123 QQLRRNVAPSND--LAQLMSQFEQLTRTVKP-------QYQVWLKASKGEEIHLIAVNEL 173 Query: 183 IYFEATDKYVNVVTADG----QALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVEAAVR 238 +Y +A DKY+++ G + L+R+SL+EL+ QLDP QFWQIHR VV V K++ R Sbjct: 174 LYVKAEDKYLSLYKVHGATTHEYLLRSSLKELLAQLDPNQFWQIHRSIVVNVGKIDKVTR 233 Query: 239 DEAGKLSLQLRGRPERLAVSRLFAPLFR 266 D GK+ + + +L VSR LF+ Sbjct: 234 DFGGKMWVHIDRL--QLPVSRALQHLFK 259 >XF1626 [KT] COG3279 Response regulator of the LytR/AlgR family Xfa Xylella fastidiosa 9a5c Length = 252 Score = 119 bits (297), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 93/260 (35%), Positives = 125/260 (48%), Gaps = 26/260 (10%) Query: 6 LIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEMALESLPDVLFLDIRMPGHSGL 65 LIA+DEPL L+ LQ LE A NG Q L PD++ +DI MPG GL Sbjct: 5 LIADDEPLARERLRVLLQAQMQHLEVVAEAENGEQVLHDCQRLNPDLVLMDIAMPGIDGL 64 Query: 66 EVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQRLRAL 125 E AR L P P +VF TAY +HAL AF+ AIDYL+KPV ERL ++R++ Sbjct: 65 ETARYL-RHLP---ACPAVVFCTAYGDHALSAFDVEAIDYLMKPVRAERLHAALKRVQTF 120 Query: 126 LAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEVIRAAVGNRTRLIPVEEVIYF 185 +A R Q S D AR IR + RLIP+++V Y Sbjct: 121 VAGRLREPQ--------------TSCDETPRTHLCAR---IRGGL----RLIPLDQVRYL 159 Query: 186 EATDKYVNVVTADGQALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVEAAVRDEAGKLS 245 +A +KYV + G+ LI SL+ L + +F +IHR ++ ++ R G++ Sbjct: 160 QADEKYVVICHEQGEDLIEESLKSLEKEF-SDRFVRIHRNCLIARAELTELRRCSDGQVQ 218 Query: 246 LQLRGRPERLAVSRLFAPLF 265 LR L VSR PL Sbjct: 219 AVLRNVVTPLGVSRRCVPLL 238 >PA5261 [KT] COG3279 Response regulator of the LytR/AlgR family Pae Pseudomonas aeruginosa Length = 248 Score = 115 bits (289), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 93/266 (34%), Positives = 136/266 (51%), Gaps = 40/266 (15%) Query: 3 VSALIAEDEPLLARALQNTLQRCWPELETPRL----AANGVQALEMALESLPDVLFLDIR 58 ++ LI +DEPL + L R +L+ R+ A+NG +AL + PD++ LDIR Sbjct: 1 MNVLIVDDEPLA----RERLARLVGQLDGYRVLEPSASNGEEALTLIDSLKPDIVLLDIR 56 Query: 59 MPGHSGLEVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKT 118 MPG GL+VA L E R+ P ++F TA+DE ALEAF+ +A+ YL+KPV E L + Sbjct: 57 MPGLDGLQVAARLCE----REAPPAVIFCTAHDEFALEAFQVSAVGYLVKPVRSEDLAEA 112 Query: 119 VQRLRALLAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEVIRAAVGNRTR--- 175 +++ A R R QL L + + P R+ + RTR Sbjct: 113 LKK-----ASRPNR----------VQLAALTKPPASGGSGP-------RSHISARTRKGI 150 Query: 176 -LIPVEEVIYFEATDKYVNVVTADGQALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVE 234 LIP+EEVI+F A KYV + A G+ L+ L+ L + +F +IHR +V ++E Sbjct: 151 ELIPLEEVIFFIADHKYVTLRHAQGEVLLDEPLKALEDEFGE-RFVRIHRNALVARERIE 209 Query: 235 AAVRDEAGKLSLQLRG-RPERLAVSR 259 R G L L+G + L VSR Sbjct: 210 RLQRTPLGHFQLYLKGLDGDALTVSR 235 >BS_lytT [KT] COG3279 Response regulator of the LytR/AlgR family Bsu Bacillus subtilis Length = 241 Score = 102 bits (255), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 68/229 (29%), Positives = 110/229 (48%), Gaps = 28/229 (12%) Query: 6 LIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEMALESLPDVLFLDIRMPGHSGL 65 LI +DE L L L+R E+E A N A + ++ PD+LFLD+ + G +G Sbjct: 5 LIVDDEMLARDELAYLLKRTNDEMEINE-AENIESAFDQMMDQKPDLLFLDVDLSGENGF 63 Query: 66 EVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQRLRAL 125 ++A+ L + + P P IVF TAYD++AL+AFE A+DYL KP +EER+ +T+++ + + Sbjct: 64 DIAKRLKKM---KHP-PAIVFATAYDQYALKAFEVDALDYLTKPFDEERIQQTLKKYKKV 119 Query: 126 LAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEVIRAAVGNRTRLIPVEEVIYF 185 Q H Q L +VG ++ +++IY Sbjct: 120 NRDIVETEQNSHAGQHKLAL-----------------------SVGESIVIVDTKDIIYA 156 Query: 186 EATDKYVNVVTADGQALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVE 234 D +VNV T D + +L + +L F ++HR VV ++ Sbjct: 157 GTEDGHVNVKTFDHSYTVSDTLVVIEKKLPDSDFIRVHRSFVVNTEYIK 205 >VC0693 [KT] COG3279 Response regulator of the LytR/AlgR family Vch Vibrio cholerae Length = 237 Score = 97.4 bits (241), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 85/266 (31%), Positives = 128/266 (48%), Gaps = 34/266 (12%) Query: 3 VSALIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEMALESLPDVLFLDIRMPGH 62 +SAL+ +DE L L ++E A+N ++ L+ + PDV+FLDI+MP Sbjct: 2 LSALLIDDERFAREELAELLAESG-QIEVIGQASNAIEGLKKINQLKPDVVFLDIQMPQI 60 Query: 63 SGLEVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQRL 122 SG+E+ L + P +VFVTAYD++AL+AFE A DYLLKPV+ ERL KTVQRL Sbjct: 61 SGIELLSML-----DPETMPEVVFVTAYDQYALQAFEDNAFDYLLKPVDTERLAKTVQRL 115 Query: 123 RALLAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEVIRAAVGNRTRLIPVEEV 182 LRQ +D P L+ I NR L+P+ EV Sbjct: 116 ----------------------LRQHKKSDYSPLTQPS--LDQIPCTGLNRIVLLPINEV 151 Query: 183 IYFEATDKYVNVVTADGQALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVEAAVRDEAG 242 + + VNV TA +A + +L+ L + + HR +V ++ + E G Sbjct: 152 EFAYSDISGVNVQTAQQKATSQLTLKVL---EEKTALVRCHRQYLVNLKAIREIKLLENG 208 Query: 243 KLSLQLRGRPERLAVSRLFAPLFRQM 268 L+ + ++ VSR + ++M Sbjct: 209 -LAEMITHAGHKVPVSRRYLKELKEM 233 >STM2158 [KT] COG3279 Response regulator of the LytR/AlgR family Sty Salmonella typhimurium LT2 Length = 239 Score = 95.9 bits (237), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 57/121 (47%), Positives = 78/121 (64%), Gaps = 6/121 (4%) Query: 3 VSALIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEMALESLPDVLFLDIRMPGH 62 + LI +DEPL L+ LQ ++E AN V+A+ + PDVLFLDI+MP Sbjct: 2 IKVLIVDDEPLARENLRILLQ-GQDDIEIVGECANAVEAIGAVHKLRPDVLFLDIQMPRI 60 Query: 63 SGLEVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQRL 122 SGLE+ L P+ +P+ IVF+TA+DE+A++AFE A DYLLKP+ E+RL KT+ RL Sbjct: 61 SGLEMVGMLD---PEHRPY--IVFLTAFDEYAIKAFEEHAFDYLLKPIEEKRLEKTLHRL 115 Query: 123 R 123 R Sbjct: 116 R 116 >ypdB [KT] COG3279 Response regulator of the LytR/AlgR family Eco Escherichia coli K12 Length = 244 Score = 94.0 bits (232), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 73/266 (27%), Positives = 121/266 (45%), Gaps = 25/266 (9%) Query: 3 VSALIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEMALESLPDVLFLDIRMPGH 62 + +I EDE LA+ + L + ++E +G+ L+ + D +FLDI +P Sbjct: 1 MKVIIVEDE-FLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSL 59 Query: 63 SGLEVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQRL 122 G+ +A+ ++ Q+ + P IVF+TA+ EHA+EAFE A DY+LKP E R+ +Q+L Sbjct: 60 DGVLLAQNIS-QFAHK---PFIVFITAWKEHAVEAFELEAFDYILKPYQESRITGMLQKL 115 Query: 123 RALLAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEVIRAAVGNRTRLIPVEEV 182 A Q+ S +P AA + I R + P+ ++ Sbjct: 116 EAAWQQQQTSS-------------------TP-AATVTRENDTINLVKDERIIVTPINDI 155 Query: 183 IYFEATDKYVNVVTADGQALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVEAAVRDEAG 242 Y EA +K V T ++ ++ E +L P F++ HR V + K+ Sbjct: 156 YYAEAHEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNN 215 Query: 243 KLSLQLRGRPERLAVSRLFAPLFRQM 268 L+L+ + VSR FRQ+ Sbjct: 216 TYILRLKDLDFEVPVSRSKVKEFRQL 241 >Z3646 [KT] COG3279 Response regulator of the LytR/AlgR family EcZ Escherichia coli O157:H7 EDL933 Length = 244 Score = 94.0 bits (232), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 73/266 (27%), Positives = 121/266 (45%), Gaps = 25/266 (9%) Query: 3 VSALIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEMALESLPDVLFLDIRMPGH 62 + +I EDE LA+ + L + ++E +G+ L+ + D +FLDI +P Sbjct: 1 MKVIIVEDE-FLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSL 59 Query: 63 SGLEVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQRL 122 G+ +A+ ++ Q+ + P IVF+TA+ EHA+EAFE A DY+LKP E R+ +Q+L Sbjct: 60 DGVLLAQNIS-QFAHK---PFIVFITAWKEHAVEAFELEAFDYILKPYQESRITGMLQKL 115 Query: 123 RALLAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEVIRAAVGNRTRLIPVEEV 182 A Q+ S +P AA + I R + P+ ++ Sbjct: 116 EAAWQQQQTSS-------------------TP-AATVTRENDTINLVKDERIIVTPINDI 155 Query: 183 IYFEATDKYVNVVTADGQALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVEAAVRDEAG 242 Y EA +K V T ++ ++ E +L P F++ HR V + K+ Sbjct: 156 YYAEAHEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNN 215 Query: 243 KLSLQLRGRPERLAVSRLFAPLFRQM 268 L+L+ + VSR FRQ+ Sbjct: 216 TYILRLKDLDFEVPVSRSKVKEFRQL 241 >ECs3261 [KT] COG3279 Response regulator of the LytR/AlgR family Ecs Escherichia coli O157:H7 Length = 244 Score = 94.0 bits (232), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 73/266 (27%), Positives = 121/266 (45%), Gaps = 25/266 (9%) Query: 3 VSALIAEDEPLLARALQNTLQRCWPELETPRLAANGVQALEMALESLPDVLFLDIRMPGH 62 + +I EDE LA+ + L + ++E +G+ L+ + D +FLDI +P Sbjct: 1 MKVIIVEDE-FLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSL 59 Query: 63 SGLEVARELAEQWPQRQPFPLIVFVTAYDEHALEAFERAAIDYLLKPVNEERLGKTVQRL 122 G+ +A+ ++ Q+ + P IVF+TA+ EHA+EAFE A DY+LKP E R+ +Q+L Sbjct: 60 DGVLLAQNIS-QFAHK---PFIVFITAWKEHAVEAFELEAFDYILKPYQESRITGMLQKL 115 Query: 123 RALLAQRAARSQELHLEQALAQLRQLVSADSPVAAAPPARLEVIRAAVGNRTRLIPVEEV 182 A Q+ S +P AA + I R + P+ ++ Sbjct: 116 EAAWQQQQTSS-------------------TP-AATVTRENDTINLVKDERIIVTPINDI 155 Query: 183 IYFEATDKYVNVVTADGQALIRTSLRELIPQLDPGQFWQIHRGTVVQVRKVEAAVRDEAG 242 Y EA +K V T ++ ++ E +L P F++ HR V + K+ Sbjct: 156 YYAEAHEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNN 215 Query: 243 KLSLQLRGRPERLAVSRLFAPLFRQM 268 L+L+ + VSR FRQ+ Sbjct: 216 TYILRLKDLDFEVPVSRSKVKEFRQL 241