BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0544.p (793 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb21301 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme S... 1002 0.0 AGl75 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Agro... 934 0.0 mll4783 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Me... 903 0.0 BH0539 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bac... 390 e-108 BS_dhaS [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Ba... 390 e-108 FN0454 [C] COG1012 NAD-dependent aldehyde dehydrogenases Fnu Fus... 371 e-102 YOR374w [C] COG1012 NAD-dependent aldehyde dehydrogenases Sce Sa... 368 e-101 YER073w [C] COG1012 NAD-dependent aldehyde dehydrogenases Sce Sa... 361 5e-99 SA0162 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sau Sta... 360 7e-99 SPAC9E9.09c [C] COG1012 NAD-dependent aldehyde dehydrogenases Sp... 357 9e-98 >SMb21301 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 794 Score = 1002 bits (2590), Expect = 0.0, Method: Compositional matrix adjust. Identities = 534/799 (66%), Positives = 627/799 (78%), Gaps = 11/799 (1%) Query: 1 MSVSTYFDTMDYGPAPESDKDARAWLASHEASFGHFIAGRFTQPKA--DLDDIDPASGKL 58 MSV+T+FD M YGPAPE+D +ARAWL HE GHFI G F + D +PA+GKL Sbjct: 1 MSVATFFDEMSYGPAPEADTEARAWLTRHEGKLGHFINGAFVGSASGKSFDTFEPATGKL 60 Query: 59 LAHLSQGSAADVDAAVQAAQAALPGWQALGGHGRARHLYALARTVQRHARLLAVLETLDN 118 LA ++ G DV+AAV AA+ A W L GH RARHLYALAR +QRHARL+AV+E LDN Sbjct: 61 LAKIAHGGRDDVNAAVAAARKAQGPWAKLSGHARARHLYALARLIQRHARLIAVVEALDN 120 Query: 119 GKPLRESRDVDVPLVARHFYHYAGWAQLQESEFPDHVPVGVVGQIVPWNFPLLMLAWKIA 178 GKP+RE+RD+D+PL ARHFYH+AGWAQLQE+EF D VPVGVVGQ++PWNFP LMLAWK+A Sbjct: 121 GKPIRETRDIDIPLAARHFYHHAGWAQLQETEFADQVPVGVVGQVIPWNFPFLMLAWKVA 180 Query: 179 PALALGNTVVLKPAENTSLTALLFAELAQQAGLPAGVLNIVTGDGATGAAVVAHPGIQKI 238 PALALGN+V+LKPAE T LTALLFAELA AGLP GVLN+VTG+G TGA +V H I KI Sbjct: 181 PALALGNSVILKPAEFTPLTALLFAELAAAAGLPPGVLNVVTGEGETGALIVEHEDIDKI 240 Query: 239 AFTGSTEVGRLIREQTAGSGKSLTLELGGKSPFIVFEDADIDAAIEGVVDAIWFNQGQVC 298 AFTGSTEVGRLIRE+TAGSGKSLTLELGGKSPFIVF+DADIDAA+EGVVDAIWFNQGQVC Sbjct: 241 AFTGSTEVGRLIREKTAGSGKSLTLELGGKSPFIVFDDADIDAAVEGVVDAIWFNQGQVC 300 Query: 299 CAGSRLLVQEGIHDLFIARLKTRMQKLKVGAPLDKCSDMGALISPVQLERVRSLVEQGVR 358 CAGSRLLVQEG+ +F RLK RM+ L+VG PLDK DM A+++PVQL+R+ LV +GV Sbjct: 301 CAGSRLLVQEGVAPVFHDRLKRRMETLRVGHPLDKAIDMAAIVAPVQLQRIEELVAKGVA 360 Query: 359 EGAQCHQVALDTPPGGCFYPPTLLTGVHPAATVASEEIFGPVLVAMSFRTPDEAVQLANN 418 EGA HQ ++ P GG F+ PTLLTGV P + VA+EEIFGPV V+M+FRTP+EA+QLAN+ Sbjct: 361 EGASMHQPKIELPKGGSFFRPTLLTGVQPTSVVATEEIFGPVAVSMTFRTPEEAIQLANH 420 Query: 419 SRYGLAASIWSETIGLALGVAPQLKAGVVWINSTNQFDAAVGFGGVRESGYGREGGREGC 478 SRYGLAAS+WSETIGLAL VA +L AGVVW+N+TN FDA+ GFGG RESG+GREGGREGC Sbjct: 421 SRYGLAASVWSETIGLALHVAAKLAAGVVWVNATNLFDASSGFGGKRESGFGREGGREGC 480 Query: 479 YEYLKPRRQQAGSLRQ----PSARRAIRADADSPLQGGAIDRTAKLYIGGKQVRPDGEVS 534 YEYLKP+ LR P+ ++A D P A+DRTAKL++GGKQ RPDG S Sbjct: 481 YEYLKPKAWMGRKLRPEHGLPAPKQAA-GDFAVP----ALDRTAKLFVGGKQARPDGNYS 535 Query: 535 MACHCAQGERLEDVGLGNRKDIRNAVAAAVKAGGWTSASPHRRAQGLYYIAENLSARTEE 594 +G+ + +VG GNRKDIRNAV AA A GW+SA+ H RAQ LYYIAENLS+R E Sbjct: 536 RPVLSPKGKVIGEVGEGNRKDIRNAVVAARGASGWSSATAHNRAQILYYIAENLSSRGAE 595 Query: 595 FARRIASTTGVTADEARAEVDASIKRLFTYGAWADKFEGAVHQPPMRGVALAMPEAIGVV 654 FA RIA+ TG +A ARAEV+ASI RLF+YGAWADK+EG VHQPP+RGVALAMPE GVV Sbjct: 596 FAGRIAAMTGASAANARAEVEASIARLFSYGAWADKYEGTVHQPPLRGVALAMPEPQGVV 655 Query: 655 GVVCPEEKPLLALISLVAPLIAMGNRVVVVPSEQAPLVATDLYQVLDTSDLPAGVINIVT 714 GV+CP E PLL L+SLVAPLIA+GNRVV VPSE PL ATD Y VL+TSD+P GVINIVT Sbjct: 656 GVICPPEAPLLGLVSLVAPLIAVGNRVVAVPSEAHPLAATDFYSVLETSDVPPGVINIVT 715 Query: 715 GKSAELLPVLAEHDEVEALWVRGPAEFSATAERLSTGNLKRCFVDHGYVTDWHDAAQGEG 774 G + EL LA H++V+ALW G E S E+LS GNLKR FVD+G DW D + EG Sbjct: 716 GSAIELAKALAAHNDVDALWAFGSPELSTLVEKLSVGNLKRTFVDYGKAIDWTDRSAAEG 775 Query: 775 AQYLRQATHIKNVWIPYGE 793 +LR+A +KN+WIPYGE Sbjct: 776 QAFLRRAVDVKNIWIPYGE 794 >AGl75 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 798 Score = 934 bits (2413), Expect = 0.0, Method: Compositional matrix adjust. Identities = 468/794 (58%), Positives = 583/794 (73%), Gaps = 4/794 (0%) Query: 3 VSTYFDTMDYGPAPESDKDARAWLASHEASFGHFIAGRFTQP--KADLDDIDPASGKLLA 60 + +TM+YGP+PE++ D + WL +H SFGH+I GRF P + + +PA+G LA Sbjct: 4 IKDILETMEYGPSPEANGDVKQWLDAHGRSFGHYINGRFVSPDGRKTIAVSNPANGDKLA 63 Query: 61 HLSQGSAADVDAAVQAAQAALPGWQALGGHGRARHLYALARTVQRHARLLAVLETLDNGK 120 + G+ DVD A++AA+AA W L GH RAR+LYA+AR +Q+ R L+VLET+DNGK Sbjct: 64 EIVCGNEEDVDQAIKAARAAFGKWSKLSGHARARYLYAIARHIQKRERFLSVLETMDNGK 123 Query: 121 PLRESRDVDVPLVARHFYHYAGWAQLQESEFPDHVPVGVVGQIVPWNFPLLMLAWKIAPA 180 P+RE+RD+D+PLVARHFYH+AGWA++ E EF PVGV GQ++PWNFPLLMLAWKIAPA Sbjct: 124 PVRETRDIDIPLVARHFYHHAGWAEMVEDEFHGFSPVGVCGQVIPWNFPLLMLAWKIAPA 183 Query: 181 LALGNTVVLKPAENTSLTALLFAELAQQAGLPAGVLNIVTGDGATGAAVVAHPGIQKIAF 240 LA GNTVVLKPA+ T LTA+ FAE+ + GLPAGV+NIV GDG+TGAA+ H G+ K+AF Sbjct: 184 LAAGNTVVLKPADLTPLTAIAFAEICHEVGLPAGVVNIVQGDGSTGAAICGHDGVDKVAF 243 Query: 241 TGSTEVGRLIREQTAGSGKSLTLELGGKSPFIVFEDADIDAAIEGVVDAIWFNQGQVCCA 300 TGST+VGR+IREQ AGSGK L+LELGGKSPFIVFEDAD+DAA+EGVVDAIWFNQG+VCCA Sbjct: 244 TGSTKVGRVIREQIAGSGKKLSLELGGKSPFIVFEDADLDAAVEGVVDAIWFNQGEVCCA 303 Query: 301 GSRLLVQEGIHDLFIARLKTRMQKLKVGAPLDKCSDMGALISPVQLERVRSLVEQGVREG 360 GSRLLVQEGI + F ARLK R++ L+VG PLDK +D+GA++S Q++R+ LV +GV EG Sbjct: 304 GSRLLVQEGIAEKFYARLKKRLETLRVGDPLDKSTDVGAIVSATQVKRITDLVRKGVEEG 363 Query: 361 AQCHQVALDTPPGGCFYPPTLLTGVHPAATVASEEIFGPVLVAMSFRTPDEAVQLANNSR 420 + Q + PP G + P T V A+TV EIFGP+ A +FRTPDEAV LANN+R Sbjct: 364 GELWQSSNPLPPTGNYVAPGFFTDVDQASTVCQVEIFGPIAAATTFRTPDEAVSLANNTR 423 Query: 421 YGLAASIWSETIGLALGVAPQLKAGVVWINSTNQFDAAVGFGGVRESGYGREGGREGCYE 480 YGLAASIWSE I +AL +A ++KAGVVWIN TN DA GFGG RESG+GREG REG YE Sbjct: 424 YGLAASIWSENINVALDLAARVKAGVVWINCTNMLDAGAGFGGYRESGFGREGAREGLYE 483 Query: 481 YLKPRRQQAGSLRQPSARRAIRA--DADSPLQGGAIDRTAKLYIGGKQVRPDGEVSMACH 538 YL ++ S+ +P+ A A +ADS +DRT K YIGGKQ RPDG S + Sbjct: 484 YLAADWEKNLSVSKPAEAFAPSALPNADSKKAIDGLDRTMKNYIGGKQARPDGGYSYSVT 543 Query: 539 CAQGERLEDVGLGNRKDIRNAVAAAVKAGGWTSASPHRRAQGLYYIAENLSARTEEFARR 598 + G+GNRKDIRNAV AA KAG W+SA+ H RAQ LYY+AENL+AR +EF R Sbjct: 544 GKGNAVIGMAGIGNRKDIRNAVEAASKAGSWSSATAHNRAQVLYYLAENLNARRDEFVAR 603 Query: 599 IASTTGVTADEARAEVDASIKRLFTYGAWADKFEGAVHQPPMRGVALAMPEAIGVVGVVC 658 I +TGV+ +AR E DAS++R+ Y A ADKF+GA+H R V LAM E G+VG+VC Sbjct: 604 IIDSTGVSEKKARDEFDASLRRISYYAAQADKFDGAIHSTKSRHVTLAMNEPWGIVGIVC 663 Query: 659 PEEKPLLALISLVAPLIAMGNRVVVVPSEQAPLVATDLYQVLDTSDLPAGVINIVTGKSA 718 P+E PLL+L+SLV P IAMGNRVVV+PS + PL+A D YQVLDTSD+P GVINIVTG+ Sbjct: 664 PDEAPLLSLVSLVLPAIAMGNRVVVIPSSRHPLIAGDFYQVLDTSDVPGGVINIVTGERD 723 Query: 719 ELLPVLAEHDEVEALWVRGPAEFSATAERLSTGNLKRCFVDHGYVTDWHDAAQGEGAQYL 778 L LAEHD+V A+W G A SA ER S GNLK +V++G DW D Q +G YL Sbjct: 724 MLAKTLAEHDDVAAIWYFGSAVGSAMVERASAGNLKAAWVNNGRQPDWLDRTQWQGRDYL 783 Query: 779 RQATHIKNVWIPYG 792 R+A +KN+W+PYG Sbjct: 784 RRAIQVKNIWVPYG 797 >mll4783 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Mesorhizobium loti Length = 781 Score = 903 bits (2334), Expect = 0.0, Method: Compositional matrix adjust. Identities = 480/787 (60%), Positives = 586/787 (74%), Gaps = 9/787 (1%) Query: 10 MDYGPAPESDKDARAWLASHEASFGHFIAGRFTQPKA--DLDDIDPASGKLLAHLSQGSA 67 M+YGPAPE+ +A AWLA+ + FI G + D +P+SGKLLA +S SA Sbjct: 1 MEYGPAPEARNEADAWLAARDFGKALFIDGAWKAASGGKTFDTSEPSSGKLLAKVSDASA 60 Query: 68 ADVDAAVQAAQAALPGWQALGGHGRARHLYALARTVQRHARLLAVLETLDNGKPLRESRD 127 AD+DAAV AA ALP W A G+ RA+ LYA+ R +QRH RL AVLE++DNGKP+RESRD Sbjct: 61 ADIDAAVAAATKALPKWSASSGYARAKVLYAIGRAMQRHQRLFAVLESIDNGKPIRESRD 120 Query: 128 VDVPLVARHFYHYAGWAQLQESEFPDHVPVGVVGQIVPWNFPLLMLAWKIAPALALGNTV 187 +DVPL RHF H+AGWAQ + +FP H VGVVGQI+PWNFPLLMLAWKIAPALA G TV Sbjct: 121 IDVPLAIRHFIHHAGWAQALDRDFPGHKGVGVVGQIIPWNFPLLMLAWKIAPALAAGCTV 180 Query: 188 VLKPAENTSLTALLFAELAQQAGLPAGVLNIVTGDGATGAAVVAHPGIQKIAFTGSTEVG 247 VLKPAE T LTA+LFAE+ ++AG+P GV+NIV G GAA+V HPGIQKIAFTGS+EVG Sbjct: 181 VLKPAEFTPLTAILFAEICERAGVPKGVVNIVQGGPEAGAAIVNHPGIQKIAFTGSSEVG 240 Query: 248 RLIREQTAGSGKSLTLELGGKSPFIVFEDADIDAAIEGVVDAIWFNQGQVCCAGSRLLVQ 307 ++IR+ TAGSGK L+LELGGKS FIVFEDAD+D+A+EG+VD IWFNQGQVCCAGSRLLVQ Sbjct: 241 KIIRKATAGSGKKLSLELGGKSAFIVFEDADLDSAVEGLVDGIWFNQGQVCCAGSRLLVQ 300 Query: 308 EGIHDLFIARLKTRMQKLKVGAPLDKCSDMGALISPVQLERVRSLVEQGVREGAQCHQVA 367 EGI + IA++KTRM +L+VG+PLDK +D+G L+ QL+RV+ LV +G ++GA C Q Sbjct: 301 EGIAEALIAKVKTRMSRLRVGSPLDKNTDIGPLVDLTQLDRVKGLVAEGAKQGAVCWQPD 360 Query: 368 LDTPPGGCFYPPTLLTGVHPAATVASEEIFGPVLVAMSFRTPDEAVQLANNSRYGLAASI 427 P G ++ PTL TGV PA +A EE+FGPVL M+FR +EA++LANN+RYGLAAS+ Sbjct: 361 AALPSSGYYHLPTLATGVSPANILAQEEVFGPVLATMTFRNTEEAIELANNTRYGLAASV 420 Query: 428 WSETIGLALGVAPQLKAGVVWINSTNQFDAAVGFGGVRESGYGREGGREGCYEYLKPRRQ 487 WSE + LAL VAPQLKAGVVW+N TN FDAA GFGG RESG+GREGGREG +EYL + Sbjct: 421 WSENVNLALHVAPQLKAGVVWVNGTNMFDAACGFGGYRESGFGREGGREGMFEYLTA-KL 479 Query: 488 QAGSLRQPSARRAIRADADSPLQGGAIDRTAKLYIGGKQVRPDGEVSMACHCAQGERLED 547 G + +P+ A+ A G AIDRTAKL+IGGKQVRPDG S+A A+G+ + Sbjct: 480 PLGPVIKPA---AVSAQPVEQADGAAIDRTAKLFIGGKQVRPDGNYSLAVATAKGKLAGE 536 Query: 548 VGLGNRKDIRNAVAAAVKAGGWTSASPHRRAQGLYYIAENLSARTEEFARRIASTTGVTA 607 VG GNRKDIR+AV+AA GW A+ + R+Q LYY+AENLS R EFA R+ TG T Sbjct: 537 VGFGNRKDIRDAVSAARACKGWPEATAYNRSQVLYYLAENLSGRAGEFAARLTELTGATP 596 Query: 608 DEARAEVDASIKRLFTYGAWADKFEGAVHQPPMRGVALAMPEAIGVVGVVCPEEKPLLAL 667 AR EVD SI+RLF Y ADKFEG VHQPP R V LA+ E +GVVG+V P+ PLL L Sbjct: 597 KAAREEVDQSIERLFLYAGLADKFEGRVHQPPARAVTLALHEPVGVVGIVAPDASPLLGL 656 Query: 668 ISLVAPLIAMGNRVVVVPSEQAPLVATDLYQVLDTSDLPAGVINIVTGKSAELLPVLAEH 727 ISLVAP +AMGN VV VPSE+ PL+ATDLYQV++ SD+PAG INIVTG+SAEL VLA+H Sbjct: 657 ISLVAPALAMGNTVVAVPSERYPLLATDLYQVIEYSDVPAGAINIVTGRSAELAGVLAKH 716 Query: 728 DEVEALWVRGPAEFSATAERLSTGNLKRCFVDHGYVTDW-HDAAQGEGAQYLRQATHIKN 786 D+V+ LWV AE A AE S GNLKR + +G DW D A G+ +LR+A +KN Sbjct: 717 DDVDGLWVFADAETCARAEAESIGNLKRVWSGNGRSLDWASDEAAGDA--FLRRAVEVKN 774 Query: 787 VWIPYGE 793 VW+PYG+ Sbjct: 775 VWVPYGD 781 >BH0539 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bacillus halodurans Length = 498 Score = 390 bits (1001), Expect = e-108, Method: Compositional matrix adjust. Identities = 209/465 (44%), Positives = 289/465 (62%), Gaps = 15/465 (3%) Query: 36 FIAGRFTQPKA--DLDDIDPASGKLLAHLSQGSAADVDAAVQAAQAALPG--WQALGGHG 91 FI G + + + ++PA+G+ LA +++ + D+D AV+AA+ A W + Sbjct: 27 FINGEWVDSFSGQSFETMNPATGETLALVAEAGSEDIDFAVKAARKAFDEGPWSKMSAAE 86 Query: 92 RARHLYALARTVQRHARLLAVLETLDNGKPLRESRDVDVPLVARHFYHYAGWA------- 144 R+R +Y LA ++ H LA LETLDNGKP+RE+ + D+PLV HF ++AGWA Sbjct: 87 RSRLIYKLADLIEDHKEALAQLETLDNGKPIRETANADIPLVIEHFRYFAGWATKIVGQT 146 Query: 145 ---QLQESEFPDHVPVGVVGQIVPWNFPLLMLAWKIAPALALGNTVVLKPAENTSLTALL 201 Q + H +GVVGQI+PWNFPLLM AWK+ ALA G TVVLKPAE T L+AL Sbjct: 147 IPVQGHYFNYTRHEAIGVVGQIIPWNFPLLMAAWKLGAALATGCTVVLKPAEQTPLSALY 206 Query: 202 FAELAQQAGLPAGVLNIVTGDG-ATGAAVVAHPGIQKIAFTGSTEVGRLIREQTAGSGKS 260 EL +AG P GV+NIV G G + G +V HP + K+AFTGST+VG+LI +Q + S K Sbjct: 207 LGELINEAGFPKGVVNIVPGFGHSAGTPLVNHPAVDKVAFTGSTDVGKLIMKQASESLKR 266 Query: 261 LTLELGGKSPFIVFEDADIDAAIEGVVDAIWFNQGQVCCAGSRLLVQEGIHDLFIARLKT 320 +TLELGGKSP I+ DAD+ A+ G + I FNQGQVCCAGSRL VQ+ +D +A L + Sbjct: 267 VTLELGGKSPNIILPDADLSKAVPGSLMGIMFNQGQVCCAGSRLYVQKKQYDHVVADLVS 326 Query: 321 RMQKLKVGAPLDKCSDMGALISPVQLERVRSLVEQGVREGAQCHQVALDTPPGGCFYPPT 380 +++ G L + + MG LIS Q RV++ +++GV EGA+ G F PT Sbjct: 327 LTNEIQQGDGLLEQTTMGPLISNQQQSRVKNYIDRGVEEGAELLTGGNIPYDQGYFVAPT 386 Query: 381 LLTGVHPAATVASEEIFGPVLVAMSFRTPDEAVQLANNSRYGLAASIWSETIGLALGVAP 440 + V + T+A EEIFGPV+ AM F + D+ + AN+S YGLAA +W++ I A +A Sbjct: 387 IFADVDHSMTIAKEEIFGPVVAAMPFDSIDDLIDKANDSDYGLAAGVWTQDIKKAHYIAH 446 Query: 441 QLKAGVVWINSTNQFDAAVGFGGVRESGYGREGGREGCYEYLKPR 485 ++KAG +W+N N FDAA FGG ++SG GRE G Y + + Sbjct: 447 RIKAGTIWVNCYNVFDAASPFGGYKQSGIGREMGSYALENYTEVK 491 Score = 84.3 bits (207), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 114/250 (45%), Gaps = 9/250 (3%) Query: 519 KLYIGGKQVRP-DGEVSMACHCAQGERLEDVGLGNRKDIRNAVAAAVKA---GGWTSASP 574 KL+I G+ V G+ + A GE L V +DI AV AA KA G W+ S Sbjct: 25 KLFINGEWVDSFSGQSFETMNPATGETLALVAEAGSEDIDFAVKAARKAFDEGPWSKMSA 84 Query: 575 HRRAQGLYYIAENLSARTEEFARRIASTTGVTADE-ARAEVDASIKRLFTYGAWADKFEG 633 R++ +Y +A+ + E A+ G E A A++ I+ + WA K G Sbjct: 85 AERSRLIYKLADLIEDHKEALAQLETLDNGKPIRETANADIPLVIEHFRYFAGWATKIVG 144 Query: 634 AVHQPPMRG--VALAMPEAIGVVGVVCPEEKPLLALISLVAPLIAMGNRVVVVPSEQAPL 691 P++G EAIGVVG + P PLL + +A G VV+ P+EQ PL Sbjct: 145 --QTIPVQGHYFNYTRHEAIGVVGQIIPWNFPLLMAAWKLGAALATGCTVVLKPAEQTPL 202 Query: 692 VATDLYQVLDTSDLPAGVINIVTGKSAELLPVLAEHDEVEALWVRGPAEFSATAERLSTG 751 A L ++++ + P GV+NIV G L H V+ + G + + ++ Sbjct: 203 SALYLGELINEAGFPKGVVNIVPGFGHSAGTPLVNHPAVDKVAFTGSTDVGKLIMKQASE 262 Query: 752 NLKRCFVDHG 761 +LKR ++ G Sbjct: 263 SLKRVTLELG 272 >BS_dhaS [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Bacillus subtilis Length = 495 Score = 390 bits (1001), Expect = e-108, Method: Compositional matrix adjust. Identities = 209/465 (44%), Positives = 282/465 (60%), Gaps = 15/465 (3%) Query: 36 FIAGRF--TQPKADLDDIDPASGKLLAHLSQGSAADVDAAVQAAQAALPG--WQALGGHG 91 +I G+F + A D +PA+G+ L L + AADVD AV+AA+ A W+ + Sbjct: 23 YIDGKFVPSASGATFDTPNPATGETLMTLYEAQAADVDKAVKAARKAFDQGEWRTMSPAS 82 Query: 92 RARHLYALARTVQRHARLLAVLETLDNGKPLRESRDVDVPLVARHFYHYAGWAQLQESE- 150 R+R +Y LA ++ H LA LETLDNGKP+ E+ + D+PL H +YAGW + Sbjct: 83 RSRLMYKLADLMEEHKTELAQLETLDNGKPINETTNGDIPLAIEHMRYYAGWCTKITGQT 142 Query: 151 ---------FPDHVPVGVVGQIVPWNFPLLMLAWKIAPALALGNTVVLKPAENTSLTALL 201 + H PVGVVGQI+PWNFPLLM WK+ ALA G T+VLKPAE T L+AL Sbjct: 143 IPVSGAYFNYTRHEPVGVVGQIIPWNFPLLMAMWKMGAALATGCTIVLKPAEQTPLSALY 202 Query: 202 FAELAQQAGLPAGVLNIVTGDGA-TGAAVVAHPGIQKIAFTGSTEVGRLIREQTAGSGKS 260 AEL QAG PAGV+NI+ G G G A+ H + KIAFTGSTE+G+ I A S K Sbjct: 203 LAELIDQAGFPAGVINIIPGFGEDAGEALTNHEAVDKIAFTGSTEIGKKIMSTAAKSIKR 262 Query: 261 LTLELGGKSPFIVFEDADIDAAIEGVVDAIWFNQGQVCCAGSRLLVQEGIHDLFIARLKT 320 +TLELGGKSP I+ DA++ AI G ++ + FNQGQVCCAGSR+ + + +D + + + Sbjct: 263 VTLELGGKSPNILLPDANLKKAIPGALNGVMFNQGQVCCAGSRVFIHKDQYDEVVDEMAS 322 Query: 321 RMQKLKVGAPLDKCSDMGALISPVQLERVRSLVEQGVREGAQCHQVALDTPPGGCFYPPT 380 + L+ GA L K + +G L+S Q ERV S +++G EGA+ G F PT Sbjct: 323 YAESLRQGAGLHKDTQIGPLVSKEQHERVLSYIQKGKDEGAKAVTGGSCPFEAGYFVAPT 382 Query: 381 LLTGVHPAATVASEEIFGPVLVAMSFRTPDEAVQLANNSRYGLAASIWSETIGLALGVAP 440 + V T+A EEIFGPVL A+ + T DE ++ AN+S YGLAA +W+E + A +A Sbjct: 383 VFANVEDEMTIAKEEIFGPVLTAIPYETVDEVIERANHSEYGLAAGLWTENVKQAHYIAD 442 Query: 441 QLKAGVVWINSTNQFDAAVGFGGVRESGYGREGGREGCYEYLKPR 485 +L+AG VW+N N FDAA FGG ++SG GRE G Y + + Sbjct: 443 RLQAGTVWVNCYNVFDAASPFGGYKQSGLGREMGSYALDNYTEVK 487 Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 74/252 (29%), Positives = 114/252 (45%), Gaps = 9/252 (3%) Query: 517 TAKLYIGGKQV-RPDGEVSMACHCAQGERLEDVGLGNRKDIRNAVAAAVKA---GGWTSA 572 T KLYI GK V G + A GE L + D+ AV AA KA G W + Sbjct: 19 TKKLYIDGKFVPSASGATFDTPNPATGETLMTLYEAQAADVDKAVKAARKAFDQGEWRTM 78 Query: 573 SPHRRAQGLYYIAENLSARTEEFARRIASTTGVTADEA-RAEVDASIKRLFTYGAWADKF 631 SP R++ +Y +A+ + E A+ G +E ++ +I+ + Y W K Sbjct: 79 SPASRSRLMYKLADLMEEHKTELAQLETLDNGKPINETTNGDIPLAIEHMRYYAGWCTKI 138 Query: 632 EGAVHQPPMRGVALAMP--EAIGVVGVVCPEEKPLLALISLVAPLIAMGNRVVVVPSEQA 689 G P+ G E +GVVG + P PLL + + +A G +V+ P+EQ Sbjct: 139 TG--QTIPVSGAYFNYTRHEPVGVVGQIIPWNFPLLMAMWKMGAALATGCTIVLKPAEQT 196 Query: 690 PLVATDLYQVLDTSDLPAGVINIVTGKSAELLPVLAEHDEVEALWVRGPAEFSATAERLS 749 PL A L +++D + PAGVINI+ G + L H+ V+ + G E + Sbjct: 197 PLSALYLAELIDQAGFPAGVINIIPGFGEDAGEALTNHEAVDKIAFTGSTEIGKKIMSTA 256 Query: 750 TGNLKRCFVDHG 761 ++KR ++ G Sbjct: 257 AKSIKRVTLELG 268 >FN0454 [C] COG1012 NAD-dependent aldehyde dehydrogenases Fnu Fusobacterium nucleatum Length = 491 Score = 371 bits (953), Expect = e-102, Method: Compositional matrix adjust. Identities = 194/435 (44%), Positives = 272/435 (62%), Gaps = 16/435 (3%) Query: 53 PASGKLLAHLSQGSAADVDAAVQAAQAALPGWQALGGHGRARHLYALARTVQRHARLLAV 112 P + +LL+ S +D+D A+++A+ A W+ RAR L +A + + LLA Sbjct: 31 PYNNELLSEFPDASESDIDFAIKSAKEAFKTWRKTTVKERARILNKIADIIDENKDLLAT 90 Query: 113 LETLDNGKPLRESRDVDVPLVARHFYHYAGW-------AQLQESEFPDHV---PVGVVGQ 162 +ET+DNGKP+RE++ VD+PL A HF ++AG A + + +F + P+GVVGQ Sbjct: 91 VETMDNGKPIRETKLVDIPLAATHFRYFAGCILADEGQATVLDEKFLSLILREPIGVVGQ 150 Query: 163 IVPWNFPLLMLAWKIAPALALGNTVVLKPAENTSLTALLFAELAQQAGLPAGVLNIVTGD 222 I+PWNFP LM AWK+APALA G+TVVLKP+ T+L+ L+ EL Q +P GV+N+VTG Sbjct: 151 IIPWNFPFLMAAWKLAPALAAGDTVVLKPSSTTTLSLLVLMELIQDV-IPKGVVNLVTGK 209 Query: 223 GAT-GAAVVAHPGIQKIAFTGSTEVGRLIREQTAGSGKSLTLELGGKSPFIVFEDADIDA 281 G+T G + HP + K+AFTGST VGR I A TLELGGKS I+ +DADI+ Sbjct: 210 GSTAGEFLKNHPDLDKLAFTGSTAVGRDIALAAAEKLIPATLELGGKSANIILDDADIEK 269 Query: 282 AIEGVVDAIWFNQGQVCCAGSRLLVQEGIHDLFIARLKTRMQKLKVGAPLDKCSDMGALI 341 A+EG I FNQGQVCCAGSR+ VQEGI+D FI++L + + +K+G PLD + MG+ I Sbjct: 270 ALEGAQLGILFNQGQVCCAGSRIFVQEGIYDEFISKLVKKFENIKIGNPLDPTTIMGSQI 329 Query: 342 SPVQLERVRSLVEQGVREGAQCHQVALDTPPGGC----FYPPTLLTGVHPAATVASEEIF 397 Q++ + VE +EG + GC F PTL+T V+ V+ EEIF Sbjct: 330 DARQVKTILDYVEIAKQEGGVILTGGVKYTENGCDKGNFVRPTLITNVNNGCRVSQEEIF 389 Query: 398 GPVLVAMSFRTPDEAVQLANNSRYGLAASIWSETIGLALGVAPQLKAGVVWINSTNQFDA 457 GPV V + F+T DE + AN+S YGL +++++ I AL +A +++ G VWIN+ NQ Sbjct: 390 GPVAVVIKFKTDDEVIAQANDSEYGLGGAVFTKNINRALKLAREIQTGRVWINTYNQIPE 449 Query: 458 AVGFGGVRESGYGRE 472 FGG ++SG GRE Sbjct: 450 HAPFGGYKKSGIGRE 464 >YOR374w [C] COG1012 NAD-dependent aldehyde dehydrogenases Sce Saccharomyces cerevisiae Length = 519 Score = 368 bits (944), Expect = e-101, Method: Compositional matrix adjust. Identities = 202/476 (42%), Positives = 276/476 (57%), Gaps = 16/476 (3%) Query: 29 HEASFGHFIAGRFTQPKAD--LDDIDPASGKLLAHLSQGSAADVDAAVQAAQAALPG--W 84 +E G FI +F K + + I+P++ + + H+ +G DV+ AVQAA A W Sbjct: 41 YEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGSW 100 Query: 85 QALGGHGRARHLYALARTVQRHARLLAVLETLDNGKPLRESRDVDVPLVARHFYHYAGWA 144 + R + LY LA +++ ++A +ETLDNGK + SR DV LV + AG+A Sbjct: 101 NGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRG-DVDLVINYLKSSAGFA 159 Query: 145 QLQESEFPD----------HVPVGVVGQIVPWNFPLLMLAWKIAPALALGNTVVLKPAEN 194 + D P+GV GQI+PWNFPLLM AWKIAPAL GNTVVLK AE+ Sbjct: 160 DKIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAES 219 Query: 195 TSLTALLFAELAQQAGLPAGVLNIVTGDGA-TGAAVVAHPGIQKIAFTGSTEVGRLIREQ 253 T L+AL ++ QAG+P GV+NIV+G G G A+ HP I+K+AFTGST GR I + Sbjct: 220 TPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQS 279 Query: 254 TAGSGKSLTLELGGKSPFIVFEDADIDAAIEGVVDAIWFNQGQVCCAGSRLLVQEGIHDL 313 A K +TLELGGKSP IVF DA++ A++ ++ I++N G+VCCAGSR+ V+E I+D Sbjct: 280 AAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDK 339 Query: 314 FIARLKTRMQKLKVGAPLDKCSDMGALISPVQLERVRSLVEQGVREGAQCHQVALDTPPG 373 FI K + +KVG P D+ + GA S +QL ++ V+ G EGA Sbjct: 340 FIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSK 399 Query: 374 GCFYPPTLLTGVHPAATVASEEIFGPVLVAMSFRTPDEAVQLANNSRYGLAASIWSETIG 433 G F PT+ V + EEIFGPV+ F++ DE + +AN+S YGLAA I + I Sbjct: 400 GYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNIN 459 Query: 434 LALGVAPQLKAGVVWINSTNQFDAAVGFGGVRESGYGREGGREGCYEYLKPRRQQA 489 AL VA ++ AG VWIN+ N F AV FGG SG GRE + YL+ + +A Sbjct: 460 TALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRA 515 Score = 76.6 bits (187), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 59/214 (27%), Positives = 94/214 (43%), Gaps = 13/214 (6%) Query: 527 VRPDGEVSMACHCAQGERLEDVGLGNRKDIRNAVAAAVKA---GGWTSASPHRRAQGLYY 583 + P E + CH +G ED D+ AV AA +A G W P R + LY Sbjct: 65 INPSTEEEI-CHIYEGR--ED-------DVEEAVQAADRAFSNGSWNGIDPIDRGKALYR 114 Query: 584 IAENLSARTEEFARRIASTTGVTADEARAEVDASIKRLFTYGAWADKFEGAVHQPPMRGV 643 +AE + + A G +R +VD I L + +ADK +G + Sbjct: 115 LAELIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHF 174 Query: 644 ALAMPEAIGVVGVVCPEEKPLLALISLVAPLIAMGNRVVVVPSEQAPLVATDLYQVLDTS 703 + + +GV G + P PLL +AP + GN VV+ +E PL A + + + + Sbjct: 175 SYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQA 234 Query: 704 DLPAGVINIVTGKSAELLPVLAEHDEVEALWVRG 737 +P GVINIV+G + + H +++ + G Sbjct: 235 GIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTG 268 >YER073w [C] COG1012 NAD-dependent aldehyde dehydrogenases Sce Saccharomyces cerevisiae Length = 520 Score = 361 bits (926), Expect = 5e-99, Method: Compositional matrix adjust. Identities = 198/472 (41%), Positives = 280/472 (59%), Gaps = 15/472 (3%) Query: 28 SHEASFGHFIAGRF--TQPKADLDDIDPASGKLLAHLSQGSAADVDAAVQAAQAAL-PGW 84 ++E G FI G F ++ K D I+P++ + + + + DVD AV AA+ A W Sbjct: 39 TYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKW 98 Query: 85 QALGGHGRARHLYALARTVQRHARLLAVLETLDNGKPLRESRDVDVPLVARHFYHYAGWA 144 + RA+ L+ LA V++H LA +E++DNGK L +R DV LV+++ GWA Sbjct: 99 SIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARG-DVALVSKYLRSCGGWA 157 Query: 145 Q--------LQESEFPDHV--PVGVVGQIVPWNFPLLMLAWKIAPALALGNTVVLKPAEN 194 ++ F + P+GV GQI+PWNFPLLM +WKI PALA GNTVVLKPAE Sbjct: 158 DKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAET 217 Query: 195 TSLTALLFAELAQQAGLPAGVLNIVTGDG-ATGAAVVAHPGIQKIAFTGSTEVGRLIREQ 253 T L+AL ++L Q+AG+PAGV+NI+ G G G + AHP ++KIAFTGST GR I + Sbjct: 218 TPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKV 277 Query: 254 TAGSGKSLTLELGGKSPFIVFEDADIDAAIEGVVDAIWFNQGQVCCAGSRLLVQEGIHDL 313 A + K +TLELGGKSP IVF DAD+D A++ + I++N G+VCCAGSR+ +Q+ +++ Sbjct: 278 AADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEE 337 Query: 314 FIARLKTRMQKLKVGAPLDKCSDMGALISPVQLERVRSLVEQGVREGAQCHQVALDTPPG 373 + +LK + LKVG P D+ GA S QL ++ V+ EGA+ Sbjct: 338 VLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSK 397 Query: 374 GCFYPPTLLTGVHPAATVASEEIFGPVLVAMSFRTPDEAVQLANNSRYGLAASIWSETIG 433 G F PT+ V + EE+FGP++ F T DE + +AN+S+YGLAA I + I Sbjct: 398 GYFVKPTVFADVKGDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDIN 457 Query: 434 LALGVAPQLKAGVVWINSTNQFDAAVGFGGVRESGYGREGGREGCYEYLKPR 485 A+ V+ ++KAG VWIN+ N F V FGG +SG GRE G Y + + Sbjct: 458 KAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTK 509 Score = 88.6 bits (218), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 73/274 (26%), Positives = 123/274 (44%), Gaps = 10/274 (3%) Query: 498 RRAIRADADSPLQ-------GGAIDRTAKLYIGGKQVRPDGEVSM-ACHCAQGERLEDVG 549 R +R + +PL+ G ++ L+I G+ V + + + + E++ V Sbjct: 17 RSLLRLYSQAPLRVPITLPNGFTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVY 76 Query: 550 LGNRKDIRNAVAAAVKA--GGWTSASPHRRAQGLYYIAENLSARTEEFARRIASTTGVTA 607 D+ AVAAA KA W+ P RA+ L+ +A+ + E A + G + Sbjct: 77 KAMEDDVDEAVAAAKKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSL 136 Query: 608 DEARAEVDASIKRLFTYGAWADKFEGAVHQPPMRGVALAMPEAIGVVGVVCPEEKPLLAL 667 AR +V K L + G WADK G V ++ E +GV G + P PLL Sbjct: 137 FCARGDVALVSKYLRSCGGWADKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMW 196 Query: 668 ISLVAPLIAMGNRVVVVPSEQAPLVATDLYQVLDTSDLPAGVINIVTGKSAELLPVLAEH 727 + P +A GN VV+ P+E PL A Q+ + +PAGV+NI+ G + L+ H Sbjct: 197 SWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAH 256 Query: 728 DEVEALWVRGPAEFSATAERLSTGNLKRCFVDHG 761 +V+ + G +++ +K+ ++ G Sbjct: 257 PDVKKIAFTGSTATGRHIMKVAADTVKKVTLELG 290 >SA0162 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sau Staphylococcus aureus N315 Length = 495 Score = 360 bits (924), Expect = 7e-99, Method: Compositional matrix adjust. Identities = 187/483 (38%), Positives = 288/483 (59%), Gaps = 21/483 (4%) Query: 21 DARAWLASHEASFGHFIAGRFTQPKAD--LDDIDPASGKLLAHLSQGSAADVDAAVQAAQ 78 + R ++A + +G FI G F + +D ++ +PA+G+ L+H+++ DVD AV+ AQ Sbjct: 4 NVRDYIAEN---YGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQ 60 Query: 79 AALPGWQALGGHGRARHLYALARTVQRHARLLAVLETLDNGKPLRESRDVDVPLVARHFY 138 A W RA+ L + + +A++ETL+NGKP+RE+ +D+P ARHF+ Sbjct: 61 EAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFH 120 Query: 139 HYAGWAQLQESEFPD----------HVPVGVVGQIVPWNFPLLMLAWKIAPALALGNTVV 188 ++A + +E D H P+GVVG +V WNFP+L+ AWKIAPA+A GNT+V Sbjct: 121 YFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIV 180 Query: 189 LKPAENTSLTALLFAELAQQAGLPAGVLNIVTGDGA-TGAAVVAHPGIQKIAFTGSTEVG 247 ++P+ +T L+ L A++ Q+ LP GV+NI+TG G+ +G A+ H G+ K++FTGST+VG Sbjct: 181 IQPSSSTPLSLLEVAKIFQEV-LPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVG 239 Query: 248 RLIREQTAGSGKSLTLELGGKSPFIVFEDADIDAAIEGVVDAIWFNQGQVCCAGSRLLVQ 307 + E A TLELGGKS I+ +DA++D A+EG+ I FNQG+VC AGSRLLV Sbjct: 240 YQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVH 299 Query: 308 EGIHDLFIARLKTRMQKLKVGAPLDKCSDMGALISPVQLERVRSLVEQGVREGAQC---- 363 E I+D + RL+ +KVG P D+ + MG+ QL++++S ++ AQ Sbjct: 300 EKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGG 359 Query: 364 HQVALDTPPGGCFYPPTLLTGVHPAATVASEEIFGPVLVAMSFRTPDEAVQLANNSRYGL 423 H++ + G F+ PTL+ +A EEIFGPVL + + EA+ +AN+S YGL Sbjct: 360 HRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGL 419 Query: 424 AASIWSETIGLALGVAPQLKAGVVWINSTNQFDAAVGFGGVRESGYGREGGREGCYEYLK 483 A ++S+ I AL +A ++ G +WIN+ NQ FGG ++SG GRE + Y + Sbjct: 420 AGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQ 479 Query: 484 PRR 486 + Sbjct: 480 VKN 482 Score = 84.3 bits (207), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/224 (29%), Positives = 106/224 (47%), Gaps = 4/224 (1%) Query: 520 LYIGGKQVRPDGEVSM-ACHCAQGERLEDVGLGNRKDIRNAVAAAVKA-GGWTSASPHRR 577 L+I G+ V+ + ++ + A GE L + KD+ +AV A +A W+ S R Sbjct: 15 LFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSER 74 Query: 578 AQGLYYIAENLSARTEEFARRIASTTGVTADEARA-EVDASIKRLFTYGAWADKFEGAVH 636 AQ L I + L A+ ++ A G E A ++ + + + + + EG V+ Sbjct: 75 AQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVN 134 Query: 637 QPPMRGVALAMPEAIGVVGVVCPEEKPLLALISLVAPLIAMGNRVVVVPSEQAPLVATDL 696 +++ E IGVVG V P+L +AP IA GN +V+ PS PL ++ Sbjct: 135 DIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEV 194 Query: 697 YQVLDTSDLPAGVINIVTGKSAELLPVLAEHDEVEALWVRGPAE 740 ++ LP GV+NI+TGK +E + HD V+ L G + Sbjct: 195 AKIFQEV-LPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTD 237 >SPAC9E9.09c [C] COG1012 NAD-dependent aldehyde dehydrogenases Spo Schizosaccharomyces pombe Length = 503 Score = 357 bits (915), Expect = 9e-98, Method: Compositional matrix adjust. Identities = 193/448 (43%), Positives = 264/448 (58%), Gaps = 16/448 (3%) Query: 53 PASGKLLAHLSQGSAADVDAAVQAAQAALPG---WQALGGHGRARHLYALARTVQRHARL 109 P++ KL+ ++ DVD AV+ A+AA W+ R R L LA ++++ Sbjct: 45 PSTEKLICEVADADEEDVDIAVKVARAAFQTDAPWRKFSSAQRGRCLSRLADCIEQNLEY 104 Query: 110 LAVLETLDNGKPLRESRDVDVPLVARHFYHYAGWAQ----------LQESEFPDHVPVGV 159 LA +ETLDNGK + +R DV A F +Y GWA ++ + H P+GV Sbjct: 105 LASIETLDNGKSITLARG-DVQAAADCFRYYGGWADKDYGQTIETDIKRFAYTRHEPIGV 163 Query: 160 VGQIVPWNFPLLMLAWKIAPALALGNTVVLKPAENTSLTALLFAELAQQAGLPAGVLNIV 219 GQI+PWNFP LM AWKIAPA+A GNT++LK AE T L+AL + + G P GV+N++ Sbjct: 164 CGQIIPWNFPFLMCAWKIAPAVACGNTIILKTAELTPLSALCLTKFVPECGFPPGVINVL 223 Query: 220 TGDGA-TGAAVVAHPGIQKIAFTGSTEVGRLIREQTAGSG-KSLTLELGGKSPFIVFEDA 277 +GDG G A+ +H I K+AFTGST VGR++ A S K +TLELGGKSP IVF DA Sbjct: 224 SGDGRRCGNAISSHMDIDKVAFTGSTGVGRMVMRAAASSNLKKVTLELGGKSPNIVFNDA 283 Query: 278 DIDAAIEGVVDAIWFNQGQVCCAGSRLLVQEGIHDLFIARLKTRMQKLKVGAPLDKCSDM 337 D+D+A I++N GQVCCAGSR+ VQE ++D FI R+ + + LKVG P + + Sbjct: 284 DLDSAAVWTNYGIFYNSGQVCCAGSRVYVQEDVYDEFIKRMVAKAKTLKVGDPFAEDTFQ 343 Query: 338 GALISPVQLERVRSLVEQGVREGAQCHQVALDTPPGGCFYPPTLLTGVHPAATVASEEIF 397 GA +S Q ER+ S +E G+ GA+ G F PT+L+ V V EEIF Sbjct: 344 GAQVSKQQYERIVSYIESGIAHGAKLEIGGKRHGNLGYFVEPTILSNVTEDMAVGKEEIF 403 Query: 398 GPVLVAMSFRTPDEAVQLANNSRYGLAASIWSETIGLALGVAPQLKAGVVWINSTNQFDA 457 GPVL + F+T +EA++ NNS YGLAA + + I A+ V+ L+AG VW+N N Sbjct: 404 GPVLAVIKFKTIEEAIRRGNNSTYGLAAGVHTNNITNAIKVSNALEAGTVWVNCYNLLHH 463 Query: 458 AVGFGGVRESGYGREGGREGCYEYLKPR 485 + FGG +ESG GRE G G Y + + Sbjct: 464 QIPFGGYKESGIGRELGSYGLTNYTQTK 491 Score = 76.6 bits (187), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 59/228 (25%), Positives = 98/228 (42%), Gaps = 6/228 (2%) Query: 535 MACHCAQGERLEDVGLGNRKDIRNAVAAAVKAGGWTSASPHRRAQGLYYIAENLSARTEE 594 + C A + EDV + ++ A AA W S +R + L +A+ + E Sbjct: 50 LICEVADADE-EDVDIA----VKVARAAFQTDAPWRKFSSAQRGRCLSRLADCIEQNLEY 104 Query: 595 FARRIASTTGVTADEARAEVDASIKRLFTYGAWADKFEGAVHQPPMRGVALAMPEAIGVV 654 A G + AR +V A+ YG WADK G + ++ A E IGV Sbjct: 105 LASIETLDNGKSITLARGDVQAAADCFRYYGGWADKDYGQTIETDIKRFAYTRHEPIGVC 164 Query: 655 GVVCPEEKPLLALISLVAPLIAMGNRVVVVPSEQAPLVATDLYQVLDTSDLPAGVINIVT 714 G + P P L +AP +A GN +++ +E PL A L + + P GVIN+++ Sbjct: 165 GQIIPWNFPFLMCAWKIAPAVACGNTIILKTAELTPLSALCLTKFVPECGFPPGVINVLS 224 Query: 715 GKSAELLPVLAEHDEVEALWVRGPAEFSATAER-LSTGNLKRCFVDHG 761 G ++ H +++ + G R ++ NLK+ ++ G Sbjct: 225 GDGRRCGNAISSHMDIDKVAFTGSTGVGRMVMRAAASSNLKKVTLELG 272