BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0537.p (367 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0585 [GEPR] COG0477 Permeases of the major facilitator superf... 287 2e-77 DR2502 [GEPR] COG0477 Permeases of the major facilitator superfa... 166 5e-41 mlr3825 [GEPR] COG0477 Permeases of the major facilitator superf... 164 2e-40 SMc03889 [GEPR] COG0477 Permeases of the major facilitator super... 160 6e-39 BMEI0267 [GEPR] COG0477 Permeases of the major facilitator super... 154 3e-37 AGc4938 [GEPR] COG0477 Permeases of the major facilitator superf... 147 5e-35 PA3532 [GEPR] COG0477 Permeases of the major facilitator superfa... 131 2e-30 YPO1221 [GEPR] COG0477 Permeases of the major facilitator superf... 118 3e-26 ybjJ [GEPR] COG0477 Permeases of the major facilitator superfami... 98 3e-20 Z1072 [GEPR] COG0477 Permeases of the major facilitator superfam... 98 3e-20 >RSc0585 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 408 Score = 287 bits (735), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 187/367 (50%), Positives = 234/367 (63%), Gaps = 6/367 (1%) Query: 1 MAQFFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSA 60 MA FFVNGAT ATWGV IP+VK RF LS+A LSLAM VA GA+ M +G W ARV + Sbjct: 42 MALFFVNGATIATWGVHIPTVKARFGLSEASLSLAMFMVAAGAIAAMKFAGGWAARVSTR 101 Query: 61 RALRQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIM 120 RA Q G+++ L+ L P + +L+ LL++FG A A FDVA++ QA VE +PI+ Sbjct: 102 RASVQAGVVFGLMTGLLMLMPSYALLLGLLVLFGIANAGFDVAINAQATTVEAHSHKPII 161 Query: 121 STLHAMFSIGGIAGAALGAVP---GLSPLAHAALVGVVTLAVSLSIGPFALPDEVRDSAA 177 S+LH MFS+GG+ GAA G V G+ H A +G++T ++L GPF LPD V Sbjct: 162 SSLHGMFSLGGMVGAAAGGVLLDLGVPAAVHCAGMGLITAGMALCAGPFMLPDHVHAPGE 221 Query: 178 TPHGADKRARRMVLVLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFSTGM 237 H R ++ + +AFL L+ EG MYDW VYMR+VAQSP A S YAAFS GM Sbjct: 222 PAHPTTGRTLLVLGL---LAFLGLVGEGAMYDWTTVYMREVAQSPEAQASAGYAAFSGGM 278 Query: 238 AAGRLTGDRIRARIGGLRTLAWSGAAGAAGIALAAAWPSPLATLGGLLLSGLGIANLMPI 297 A R GD RAR G R L SG GI LA WP P A L G L G+G AN++PI Sbjct: 279 ALARFGGDAARARWGNTRVLGVSGVLATGGILLALLWPDPAAVLAGFALMGVGAANMVPI 338 Query: 298 FFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLRLSFVGVALVMTVVAL 357 FF+ A+R+PG+ AAE IAAVARFAYVGML+GPVFIG +A H LR VAL M ++A+ Sbjct: 339 FFVTASRMPGVPAAEGIAAVARFAYVGMLIGPVFIGMIAHHSNLRWGLSLVALTMMLIAV 398 Query: 358 FGGKAVR 364 G +A+R Sbjct: 399 AGPRAIR 405 >DR2502 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 471 Score = 166 bits (421), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 147/381 (38%), Positives = 191/381 (50%), Gaps = 34/381 (8%) Query: 2 AQFFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSAR 61 A F +NGA FATW V IP V+ L++A + A+LAV G+LL+M +G W+AR GS R Sbjct: 98 AVFLINGALFATWAVNIPGVRTALHLTEAQVGAALLAVGLGSLLSMPLTGGWVARWGSGR 157 Query: 62 ALRQVGILYAATLRLIP--LAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPI 119 + L L L+P P W L L + G A DVAM+ Q VE RP+ Sbjct: 158 VTALLAPL--TMLSLLPPFFMPSLWWLTAALGLLGVLNGALDVAMNAQGVTVEKALGRPV 215 Query: 120 MSTLHAMFSIGGIAGAALG-AVPGLSP-LAHAALVGVVTLAVSLSIGPFAL------PDE 171 MS LHA FS+GG+ GA LG A+ G P LAH V +++ +L G F L P+ Sbjct: 216 MSRLHAYFSLGGVVGALLGTALVGRVPMLAHVGGVALLSTLTALVAGRFLLADAPTEPET 275 Query: 172 VRDSAATPHGADKRARRMVLVLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYA 231 + A TP A ++ + FL ++ EG YDWAA+Y RDV P YA Sbjct: 276 AQADAPTPRSGLSPAALLLGG---LCFLGMLSEGAHYDWAALYCRDVLGLPGGQAGVGYA 332 Query: 232 AFSTGMAAGRLTGDRIRARIGGLRTL----AWSGAAGAAGIALAAAWPSPLATLGGLLLS 287 AF T M GR GDR RAR G + + S + + WP+ L G LS Sbjct: 333 AFVTTMTLGRWFGDRARARFGDVAMVRAGALLSALGLGLALLVREPWPATL----GFALS 388 Query: 288 GLGIANLMPIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLR----L 343 GLG++N++P+ + AA IA VA Y G LLGP IG +A+H GL L Sbjct: 389 GLGLSNVVPVMYGAAGHA---LHGRGIAQVATIGYGGFLLGPPLIGFLAQHSGLPAALGL 445 Query: 344 SFVGVALVMTVVALFGGKAVR 364 + G AL VA GG A R Sbjct: 446 AVAGSAL----VAGLGGVAFR 462 >mlr3825 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 391 Score = 164 bits (416), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 126/366 (34%), Positives = 188/366 (51%), Gaps = 5/366 (1%) Query: 2 AQFFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSAR 61 A F NG +W IP R +S L L +L GA+ M G I++ GS Sbjct: 19 AIFLANGFLTGSWAPQIPVFLTRLDISKFTLGLLILLFGAGAVTAMTWCGHLISKHGSRT 78 Query: 62 ALRQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMS 121 LR G+ + L ++ LAP + + + +FG ++ DVAM+ A +VE + +R IMS Sbjct: 79 VLRWFGLCGSLGLLVVALAPNLPLAAIAMFIFGGSIGGMDVAMNANAVVVERKMSRAIMS 138 Query: 122 TLHAMFSIGGIAGAALGA--VPGLSPLAHAALVGVVTLA-VSLSIGPFALPDEVRDSAAT 178 + H +S+GG AG LG + LAHAA+V V+ A +++++G D + AA Sbjct: 139 SSHGFWSLGGFAGGGLGGFAIQHYGHLAHAAVVTVLAFAAIAMAVGYLVAED--KPQAAE 196 Query: 179 PHGADKRARRMVLVLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFSTGMA 238 H A +V ++G +A L ++ EG + DWAA+Y+R + LA +YAAFS MA Sbjct: 197 HHKFALPANPLVYLIGLMALLTMVSEGAVLDWAALYLRQELGADLAIAGLAYAAFSGVMA 256 Query: 239 AGRLTGDRIRARIGGLRTLAWSGAAGAAGIALAAAWPSPLATLGGLLLSGLGIANLMPIF 298 R GD +R R G + TL S A G+ +A PSP + G GIAN++PI Sbjct: 257 IMRFFGDGVRNRFGAVTTLRGSAVVAATGMLVAGLSPSPWFAIAAFATCGFGIANMVPII 316 Query: 299 FLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLRLSFVGVALVMTVVALF 358 F A GM++ ++ V Y G+L+ P IG VAEH F+ +++++ VV L Sbjct: 317 FSAGGNQEGMSSGTGMSVVTTMGYSGILVAPSAIGFVAEHSSFGPIFIAMSVLLIVVLLM 376 Query: 359 GGKAVR 364 G A R Sbjct: 377 AGLAHR 382 >SMc03889 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 379 Score = 160 bits (404), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 124/375 (33%), Positives = 189/375 (50%), Gaps = 27/375 (7%) Query: 4 FFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 63 F +NG +W IP KER + ++VL L +L G+L+ M +G +IAR+GS + + Sbjct: 12 FLMNGFVTGSWAPKIPEFKERLGIGESVLGLLILGFGIGSLVLMPIAGGFIARLGSQKVV 71 Query: 64 RQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMSTL 123 + I+ + L L+ L P W L + + G + A DVAM+ A VE R IMS+ Sbjct: 72 KVTAIILSPLLLLLTLLPNLWTAALGMFLLGGFVGAMDVAMNANAVEVEKSMRRAIMSSC 131 Query: 124 HAMFSIGGIAG--------AALGAVPGLSPLAHAALVGVVTLAVSLSIGPFALPDEVRDS 175 HA +S+GG+ G A G +P HA +V + LA+ P L D Sbjct: 132 HAYWSLGGLIGAGIGGFLMARFGVLP------HAIVVTCLCLAILAVAWPMILADR---- 181 Query: 176 AATPHGADKRAR-RMVL-----VLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYS 229 PH A R + R+ + ++G +A +++ EG + DW A+Y++D + + + Sbjct: 182 ---PHPAATREKLRLPMTPLPWLIGIMALFSMVPEGAVLDWGALYLKDELGASVELSGFG 238 Query: 230 YAAFSTGMAAGRLTGDRIRARIGGLRTLAWSGAAGAAGIALAAAWPSPLATLGGLLLSGL 289 +AAFS MAA R GD +R R+G TL AG+ LA P+ + + G L+G+ Sbjct: 239 FAAFSATMAAMRFAGDHVRDRLGATLTLRICTVTALAGMVLAGLAPNAVLAILGFALAGI 298 Query: 290 GIANLMPIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLRLSFVGVA 349 GI+N++PI F AA +PG+ ++ Y GML P IG +AEH G + F V Sbjct: 299 GISNMVPIAFSAAGNMPGLQPGIGLSVATTMGYSGMLFAPSLIGFIAEHSGFAIIFACVP 358 Query: 350 LVMTVVALFGGKAVR 364 ++ VV L AV Sbjct: 359 VLFIVVLLLSHHAVH 373 >BMEI0267 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 397 Score = 154 bits (389), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 107/347 (30%), Positives = 165/347 (47%), Gaps = 15/347 (4%) Query: 4 FFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 63 F +NG F W IP ER L A + L +L G+L M +G A GS + Sbjct: 29 FLMNGYIFGGWAPKIPEFAERLGLDSAGMGLMILVCGLGSLAMMPVAGALSAHRGSGIVV 88 Query: 64 RQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMSTL 123 R + + L +I L P V+++L FG MAA DV+M+ A VE + R IMS+ Sbjct: 89 RIFALAFIPALLIITLVPNVVTAVIVMLYFGGTMAAMDVSMNANAVAVEKKMRRAIMSSC 148 Query: 124 HAMFSIGGIAGAALGA--VPGLSPLAHAALVGVVTLAVSLSIGPFALPDEVRDSAATPHG 181 HA +S+GG+ GAA G + + HA + + + + P +PD H Sbjct: 149 HAFWSLGGLIGAATGGFLIAQFGSIVHALVTMIAATILIIVAWPSIIPDTEH------HH 202 Query: 182 ADKRARRMVL-------VLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFS 234 D +++ L ++G +A +++ EG + DW A +MR + + + +AAFS Sbjct: 203 PDGEKQKLALPRNPLPWLVGVMALFSMVPEGAILDWGAYHMRQDLGASVTVAGFGFAAFS 262 Query: 235 TGMAAGRLTGDRIRARIGGLRTLAWSGAAGAAGIALAAAWPSPLATLGGLLLSGLGIANL 294 MA R GD +R R G ++TL A G+ + S + G + G+GI+N+ Sbjct: 263 GSMAVMRFAGDLVRDRFGAVKTLRACTAIAIIGMLIVGFGNSSATAIIGFAICGIGISNM 322 Query: 295 MPIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGL 341 +PI F A +PG+ + ++ Y GML+ P IG VA H G Sbjct: 323 VPIAFSMAGNMPGVNPSVGLSIATTLGYSGMLVAPSLIGFVARHSGF 369 >AGc4938 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 398 Score = 147 bits (370), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 110/346 (31%), Positives = 177/346 (51%), Gaps = 15/346 (4%) Query: 4 FFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 63 F +NG +W IP R +LS++ L L +L G+L+ M +G IAR GS Sbjct: 30 FLMNGFMMGSWAPKIPEFAARLSLSESALGLIILVFGIGSLVFMPIAGSQIARFGSRTVS 89 Query: 64 RQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMSTL 123 ++ TL I A W V+ + +FG A DVAM+ A VE R IMS+ Sbjct: 90 LVTAAIFLPTLLFISWAGTVWAGVIAVFLFGGLTGAMDVAMNANAVAVERDMRRAIMSSC 149 Query: 124 HAMFSIGGIAGAALGA--VPGLSPLAHAALVGVVTLAVSLSIGPFALPDEVRDSAATPHG 181 HA +S+GG+ GA LG + + HA + ++ L + + P L D PH Sbjct: 150 HAFWSLGGLIGAGLGGYLITAIGVQGHAIALTIIALVLLVIAWPRVLADR-------PHP 202 Query: 182 ADKRAR------RMVLVLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFST 235 ++R + + ++G +A +++ EG + DW A+Y+R+ + ++ +++AAFS Sbjct: 203 EEERPKGGLPLTPLPWIIGLMALFSMIPEGAILDWGALYLRNELGASVSQSGFAFAAFSM 262 Query: 236 GMAAGRLTGDRIRARIGGLRTLAWSGAAGAAGIALAAAWPSPLATLGGLLLSGLGIANLM 295 MAA R GD +R + G + TL + A G+ +A + + G ++G+GI+N++ Sbjct: 263 TMAAMRFAGDLVRDKFGAVNTLRFCSAMSIIGLIIAGVAGNSTIAIIGFAIAGIGISNMV 322 Query: 296 PIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGL 341 PI F AA +PG+A ++ V Y G+L+ P IG +AEH GL Sbjct: 323 PIAFSAAGNMPGLAPGIGLSVVTTMGYSGILVAPSAIGFIAEHTGL 368 >PA3532 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 383 Score = 131 bits (330), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 110/330 (33%), Positives = 167/330 (50%), Gaps = 9/330 (2%) Query: 18 IPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARALRQVGILYAATLRLI 77 IP++KE+ L + L A+L V GAL SG + R+GS + ++ L+ Sbjct: 31 IPALKEQTQLDERALGQALLGVGVGALTAFPLSGFLVQRIGSRSVVIGGCLIMLLVFPLL 90 Query: 78 PLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMSTLHAMFSIG-GIAGAA 136 L+ +W L L V G + A DVAM++QA VE +P MS LH M+S+G + + Sbjct: 91 GLSQGWWQLALAFYVLGVSFAGMDVAMNIQAVDVERLLGKPCMSMLHGMYSLGCLVGALS 150 Query: 137 LGAVPGLSPLAHAALVGVVTLAVSLSIGPF----ALPDEVRDSAATPHGADKRARRMVLV 192 A+ GL+P H ++ A+ L PF LP + + A G R +L Sbjct: 151 AAALAGLTPFWHF----LILTALGLLSLPFFVRALLPPDPSKAGARKGGGFTLPPRALLG 206 Query: 193 LGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFSTGMAAGRLTGDRIRARIG 252 LG + A + EGG+ DW+A+++ V + + +AAFS M GRL GDR+R RI Sbjct: 207 LGLLILCAFVSEGGVADWSALFLHSVLDASERVAALGFAAFSAAMVVGRLFGDRLRGRID 266 Query: 253 GLRTLAWSGAAGAAGIALAAAWPSPLATLGGLLLSGLGIANLMPIFFLAAARVPGMAAAE 312 L G+ G+ +A P P ++ G + GLG++ ++PI AA PG+ Sbjct: 267 DAPLLRGLGSLATLGMLVALFSPWPALSIAGFGVVGLGLSVMVPIVISAAGNQPGIDPVI 326 Query: 313 SIAAVARFAYVGMLLGPVFIGGVAEHLGLR 342 +AAV+ Y G+L+GP IG +A +GLR Sbjct: 327 GVAAVSTVGYGGLLMGPPLIGLLAHEIGLR 356 >YPO1221 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 384 Score = 118 bits (295), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 120/358 (33%), Positives = 180/358 (50%), Gaps = 10/358 (2%) Query: 4 FFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 63 FF+ G A W L+P K R L+DA L L +L + G++L M +G A+ G + Sbjct: 24 FFIAGLGMAAWAPLVPFAKARIGLNDASLGLLLLCIGIGSMLAMPLTGVLTAKWGCRAVI 83 Query: 64 RQVGILYAATLRLIPLAPQFWMLVLLLLVFGSAMAAFDVAMSVQAALVEGQRTRPIMSTL 123 G + L L+ L + + LLVFG+AM DVAM++QA +VE R +MS Sbjct: 84 LLAGAVLCLDLPLLVLMNTPATMAIALLVFGAAMGIIDVAMNIQAVIVEKASGRAMMSGF 143 Query: 124 HAMFSIGGIAGAALGAVP---GLSPLAHAALVGVVTLAVSLSIGPFALPDEVRDSAATPH 180 H +FS+GGI GA + GL+PL A++ V L + I A + + PH Sbjct: 144 HGLFSVGGIVGAGGVSALLWLGLNPLT--AIMATVVLMI---ILLLAANKNLLRGSGEPH 198 Query: 181 GADKRA--RRMVLVLGGIAFLALMCEGGMYDWAAVYMRDVAQSPLAWVSYSYAAFSTGMA 238 R V+ +G + F+ + EG M DW+AV++ + + YA F+ M Sbjct: 199 DGPLFVFPRGWVMFIGFLCFVMFLAEGSMLDWSAVFLTTLRGMSPSQAGMGYAVFAIAMT 258 Query: 239 AGRLTGDRIRARIGGLRTLAWSGAAGAAGIALAAAWPSPLATLGGLLLSGLGIANLMPIF 298 GRL GDRI +G + L A GI +A + S +A + G +L G G +N++PI Sbjct: 259 LGRLNGDRIVNGLGRYKVLLGGSLCSAIGIIIAISIDSSMAAIIGFMLVGFGASNVVPIL 318 Query: 299 FLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLRLSFVGVALVMTVVA 356 F AA M A ++A++ Y G+L GP IG +A+ L ++F VAL++ VA Sbjct: 319 FTAAGNQTVMPANLAVASITTIGYAGILAGPAAIGFIAQLSSLSVAFGCVALLLLTVA 376 >ybjJ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 402 Score = 97.8 bits (242), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 100/359 (27%), Positives = 172/359 (47%), Gaps = 31/359 (8%) Query: 4 FFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 63 FF+ G A+W P++++ ++S A + + ++ G++ + S + R G+ + Sbjct: 21 FFLPGLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVI 80 Query: 64 RQVGILYAATLRLIPLAPQFWMLVLLLL-----VFGSAMAAFDVAMSVQAALVEGQRTRP 118 + A + ++ L+ W+ LL VFG++ + +VA++V+ A VE + + Sbjct: 81 LVT--MSCALIGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKT 138 Query: 119 IMSTLHAMFSIGGIAGAALG------AVPGLSPLAHAALVGVVTLAVSLSIGPFALPDEV 172 ++ +H +S+G +AGA +G VP + AALVG+ + +++ A+PD Sbjct: 139 VLPMMHGFYSLGTLAGAGVGMALTAFGVPATVHILLAALVGIAPIYIAIQ----AIPDGT 194 Query: 173 RDSAA--TPHGAD--KRARRMVLVLGGIAFLAL-MCEGGMYDWAAVYMRDVAQSPLAWVS 227 +AA T HG R + L+L G+ LA+ EG DW + M D S Sbjct: 195 GKNAADGTQHGEKGVPFYRDIQLLLIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGS 254 Query: 228 YSYAAFSTGMAAGRLTGDRIRARIGGLRTLAWSGAAGAAGIAL----AAAWPSPLATLGG 283 YA F+ GM GR TG R + + S GA GI L +AW + ++ Sbjct: 255 LIYAGFTLGMTVGRFTGGWFIDRYSRVAVVRASALMGALGIGLIIFVDSAWVAGVS---- 310 Query: 284 LLLSGLGIANLMPIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLR 342 ++L GLG + P+ ++AA G A ++ VA Y+ L+GP +G + EH GLR Sbjct: 311 VVLWGLGASLGFPL-TISAASDTGPDAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLR 368 >Z1072 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 402 Score = 97.8 bits (242), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 102/360 (28%), Positives = 175/360 (48%), Gaps = 33/360 (9%) Query: 4 FFVNGATFATWGVLIPSVKERFALSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 63 FF+ G A+W P++++ ++S A + + ++ G++ + S + R G+ + Sbjct: 21 FFLPGLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVI 80 Query: 64 RQVGILYAATLRLIPLAPQFWMLVLLLL-----VFGSAMAAFDVAMSVQAALVEGQRTRP 118 + A + ++ L+ W+ LL VFG++ + +VA++V+ A VE + + Sbjct: 81 LVT--MSCALVGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKT 138 Query: 119 IMSTLHAMFSIGGIAGAALG------AVPGLSPLAHAALVGVVTLAVSLSIGPFALPDEV 172 ++ +H +S+G +AGA +G VP + AALVG+ + +++ A+PD Sbjct: 139 VLPMMHGFYSLGTLAGAGVGMALTAFGVPATVHILLAALVGIAPIYIAIQ----AIPDGT 194 Query: 173 RDSAA--TPHGAD--KRARRMVLVLGGIAFLAL-MCEGGMYDWAAVYMRDVAQSPLAWVS 227 +AA T HG R + L+L G+ LA+ EG DW + M D S Sbjct: 195 GKNAADGTQHGEKGVPFYRDIQLLLIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGS 254 Query: 228 YSYAAFSTGMAAGRLTG----DRIRARIGGLRTLAWSGAAGAAGIALA-AAWPSPLATLG 282 YA F+ GM GR TG DR +R+ +R A GA G I +AW + ++ Sbjct: 255 LIYAGFTLGMTVGRFTGGWFIDR-YSRVAVVRAXALMGALGIGLIIFVDSAWVAGVS--- 310 Query: 283 GLLLSGLGIANLMPIFFLAAARVPGMAAAESIAAVARFAYVGMLLGPVFIGGVAEHLGLR 342 ++L GLG + P+ ++AA G A ++ VA Y+ L+GP +G + EH GLR Sbjct: 311 -VVLWGLGASLGFPL-TISAASDTGPDAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLR 368