BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0520.p (313 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2206 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 194 3e-49 AGc4269 [K] COG0583 Transcriptional regulator Atu Agrobacterium ... 180 3e-45 SMb20896 [K] COG0583 Transcriptional regulator Sme Sinorhizobium... 166 5e-41 Z3395 [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 150 4e-36 ECs3032 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 150 4e-36 mlr5660 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 149 1e-35 STM1625 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 145 8e-35 SMb20580 [K] COG0583 Transcriptional regulator Sme Sinorhizobium... 138 1e-32 ydcI [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 133 5e-31 STM2180 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 133 5e-31 >PA2206 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 315 Score = 194 bits (492), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 105/276 (38%), Positives = 163/276 (59%) Query: 30 NIHRAASELNMTQPAASKQLKDLEDMLGVALFERLPRGMRPTIYGEAMIRHARMALTSLS 89 ++ RAA E+ MTQPAA+K L + ED+LGV LFERLPRGMR T +GE +I ++RM LS Sbjct: 30 SLRRAADEIGMTQPAATKMLHEAEDLLGVELFERLPRGMRATPFGETLIYYSRMIFAELS 89 Query: 90 KAHEDIVALKSGLSGQVDVGGILSPAMALLPPAIARVKEQAPMLRIGVEVESSNILLSRL 149 E++VAL+SG G+V VG I + A +LL IA +K+ P L + ++V++S++L+ L Sbjct: 90 GMREELVALESGNLGRVTVGAIPALASSLLTRTIATLKQSHPRLSMSIQVDTSDVLVQAL 149 Query: 150 LHGELDFIIGRILDDEARGGLLYEELADEPICAVARVGHPFHARTDLSLADLASEAWIMA 209 +LD ++GRI L+++ L +E +C V +P L +L W++ Sbjct: 150 QQDQLDVVLGRIPSGARTDDLVFDSLGEEELCVVVGAQNPLSQARKLDWGELQELTWVLQ 209 Query: 210 PKGSILRARCDQMFREQGLAPPSNVVDTTAILFITSLLQQTDFIYAMPTEVARYYTQARL 269 S +R +Q F + PS++V+TT+I+ + SLLQQTD I P V Y L Sbjct: 210 QHPSPMRGIVNQAFHNARIDLPSSIVETTSIMTLLSLLQQTDMIGITPRSVIEDYPGKHL 269 Query: 270 MDILPIELPCRMAGFGIITRQDNLLSPGANLVLQAI 305 + ILPI+L R+ +G+ITR++ + S + ++ Sbjct: 270 LAILPIQLEPRLPPYGLITRRNRVHSSAMQTFMASV 305 >AGc4269 [K] COG0583 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 341 Score = 180 bits (457), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 107/299 (35%), Positives = 167/299 (55%), Gaps = 4/299 (1%) Query: 7 NWFLRARLKTRQLLLLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERLPR 66 N LRA LK L +L+ +++ + AA+ +NMTQPAAS+ L ++E ++ L +R R Sbjct: 29 NPLLRAGLKMSHLRMLVMIEEHGQVSAAAAAMNMTQPAASRMLSEMEAIVKSPLCQRASR 88 Query: 67 GMRPTIYGEAMIRHARMALTSLSKAHEDIVALKSGLSGQVDVGGILSPAMALLPPAIARV 126 G+ T +GEA+ R AR L L +A ++ +KSG G V +G + +PA++L+ PAI R Sbjct: 89 GVVLTKFGEALARRARTILLELREASRELNQMKSGSGGSVYIGAVTAPAISLVVPAIRRA 148 Query: 127 KEQAPMLRIGVEVESSNILLSRLLHGELDFIIGRILDDEARGGLLYEELADEPICAVARV 186 + P + I V+VESSN+L LL DFIIGRI DD G E+ E C V R Sbjct: 149 MDTYPGIEINVQVESSNVLARELLAARHDFIIGRIPDDFDPGLFSIHEIGIERACLVVRE 208 Query: 187 GHPFHARTDLSLADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFITSL 246 GHP ++L DL+ W+ P G++LR + +F G+A P NV++T +++ +L Sbjct: 209 GHPLMRGEPVTLQDLSGYDWVFQPPGALLRRTMEDVFLTHGVAMPRNVINTPSVVLTLAL 268 Query: 247 LQQTDFIYAMPTEVARYYT--QARL--MDILPIELPCRMAGFGIITRQDNLLSPGANLV 301 + T+ I + ++A + QA + ILP + + + IIT + +L P A L+ Sbjct: 269 VCNTNAIAPIAQDMAEFVAGQQADIGRTRILPTDFELVVKPYSIITTKGRVLPPSARLL 327 >SMb20896 [K] COG0583 Transcriptional regulator Sme Sinorhizobium meliloti Length = 302 Score = 166 bits (421), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 103/296 (34%), Positives = 161/296 (54%), Gaps = 4/296 (1%) Query: 14 LKTRQLLLLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERLPRGMRPTIY 73 +K L L++A+DD R I AA L ++QPAAS+ L ++E ++ + ER+ RG+ T Y Sbjct: 1 MKINHLRLILAIDDHRRISAAADSLGISQPAASRMLAEIEAIVKAPICERVARGVELTRY 60 Query: 74 GEAMIRHARMALTSLSKAHEDIVALKSGLSGQVDVGGILSPAMALLPPAIARVKEQAPML 133 GEA+ R AR L +A +I LK+G G V +G + P + L PAI +V P + Sbjct: 61 GEALARRARTIFLELREAAREINELKTGSGGSVSLGSVTGPGLNLAVPAIRQVSTAYPGI 120 Query: 134 RIGVEVESSNILLSRLLHGELDFIIGRILDDEARGGLLYEELADEPICAVARVGHPFHAR 193 I V++++SN+L LL DFI+GRI DD E+ E +C + R GHP + Sbjct: 121 EINVQIDNSNVLTRELLAARHDFIVGRIPDDLNPRLFNLVEIGFEEVCLIVREGHPLLDK 180 Query: 194 TDLSLADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFITSLLQQTDFI 253 S DL + W+ P G++LR + F G+ P+ V++T++ + S+++ T+ I Sbjct: 181 ASASAHDLPAYDWVFQPPGTLLRRAVEDSFASAGVRLPATVINTSSTILTLSIVRNTNAI 240 Query: 254 YAMPTEVARYY----TQARLMDILPIELPCRMAGFGIITRQDNLLSPGANLVLQAI 305 + +VAR T+A + ILP E P R+ +G+IT + L P A L+ I Sbjct: 241 APVALDVARLVAGNGTEAGEIRILPTEFPIRIKPYGLITAEGRALPPSAKLLYDLI 296 >Z3395 [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 318 Score = 150 bits (379), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 95/288 (32%), Positives = 153/288 (53%), Gaps = 8/288 (2%) Query: 7 NWFLRARLKTRQLLLLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERLPR 66 NW +LK L +L+AL + N+ A +N+TQPA SK L LED +G+ LFER + Sbjct: 19 NW--AQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSK 76 Query: 67 GMRPTIYGEAMIRHARMALTSLSKAHEDIVALK-SGLSGQVDVGGILSP-AMALLPPAIA 124 G+RPT G+ +++HA+ + + ++ ++ K GL G + +G SP A + AI Sbjct: 77 GLRPTEGGKLLLQHAQRLINDMERSQHELARFKQGGLVGSLKIG--CSPVATDCVSQAIL 134 Query: 125 RVKEQAPMLRIGVEVESSNILLSRLLHGELDFIIGRILDDEARGGLLYEELADEPICAVA 184 + + P L + +E + LL LL G +D ++GRI + L Y+ L EP+C VA Sbjct: 135 HLLTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRALQLPLNYQVLYTEPVCFVA 194 Query: 185 RVGHPFHARTDLSLADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFIT 244 R HP LS DLA+ WI+ P G+ +R D + G+ P N +++ ++ T Sbjct: 195 RPEHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVST 254 Query: 245 SLLQQTDFIYAMPTEVA-RYYTQARLMDILPIELPCRMAGFGIITRQD 291 +LLQ +D I + +A RY +Q +L+ IL + + G+ R + Sbjct: 255 NLLQSSDMISILSLRLAQRYASQGQLV-ILNLPKIEQKGSVGVFWRNN 301 >ECs3032 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 318 Score = 150 bits (379), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 95/288 (32%), Positives = 153/288 (53%), Gaps = 8/288 (2%) Query: 7 NWFLRARLKTRQLLLLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERLPR 66 NW +LK L +L+AL + N+ A +N+TQPA SK L LED +G+ LFER + Sbjct: 19 NW--AQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSK 76 Query: 67 GMRPTIYGEAMIRHARMALTSLSKAHEDIVALK-SGLSGQVDVGGILSP-AMALLPPAIA 124 G+RPT G+ +++HA+ + + ++ ++ K GL G + +G SP A + AI Sbjct: 77 GLRPTEGGKLLLQHAQRLINDMERSQHELARFKQGGLVGSLKIG--CSPVATDCVSQAIL 134 Query: 125 RVKEQAPMLRIGVEVESSNILLSRLLHGELDFIIGRILDDEARGGLLYEELADEPICAVA 184 + + P L + +E + LL LL G +D ++GRI + L Y+ L EP+C VA Sbjct: 135 HLLTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRALQLPLNYQVLYTEPVCFVA 194 Query: 185 RVGHPFHARTDLSLADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFIT 244 R HP LS DLA+ WI+ P G+ +R D + G+ P N +++ ++ T Sbjct: 195 RPEHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVST 254 Query: 245 SLLQQTDFIYAMPTEVA-RYYTQARLMDILPIELPCRMAGFGIITRQD 291 +LLQ +D I + +A RY +Q +L+ IL + + G+ R + Sbjct: 255 NLLQSSDMISILSLRLAQRYASQGQLV-ILNLPKIEQKGSVGVFWRNN 301 >mlr5660 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 296 Score = 149 bits (375), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 96/296 (32%), Positives = 162/296 (54%), Gaps = 9/296 (3%) Query: 21 LLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERLPRGMRPTIYGEAMIRH 80 +++ALDD + AA +N++QPAAS+ + ++E +L V L +RLPRG+ T YG+A+ R Sbjct: 3 MIVALDDHGRVSAAAQVMNISQPAASRMIAEMEAVLEVKLCDRLPRGITLTPYGKALARR 62 Query: 81 ARMALTSLSKAHEDIVALKSGLSGQVDVGGILSPAMALLPPAIARVKEQAPMLRIGVEVE 140 R L + + +I LK+G G V +G + +PA+ L PAI ++ P + I ++VE Sbjct: 63 GRSILLEMREVDREISELKAGKGGSVFLGAVTAPAIELAVPAIREIRRIYPRIEITMQVE 122 Query: 141 SSNILLSRLLHGELDFIIGRILDDEARGGLLYEE--LADEPICAVARVGHPFHARTDLSL 198 +SN+L L+ DFII RI DD L+E + E C + R GHP + + + L Sbjct: 123 TSNVLARELIASRHDFIIARIPDD--LNPRLFESRVIGVEKACLIVRRGHPLTSGSVVRL 180 Query: 199 ADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFITSLLQQTDFIYAMPT 258 D A+ W+ GS LR + F + +A P +++T+++L ++ Q+D I + Sbjct: 181 EDTAAYDWVFQSGGSPLRQAMESNFLNRNIALPDRILNTSSLLLTLVMVAQSDAIAPVSV 240 Query: 259 EVARYYTQ----ARLMDILPIELPCRMAGFGIITRQDNLLSPGANLVLQAI-REVA 309 +VA++ A +D++ E + + +IT ++ LSP A ++ I REV Sbjct: 241 QVAKFIQNPDGLAGAIDVVQTEFDIEVRPYSLITVRNRALSPAAKMLHDFILREVG 296 >STM1625 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 307 Score = 145 bits (367), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 96/305 (31%), Positives = 159/305 (52%), Gaps = 5/305 (1%) Query: 5 DPNWFLRARLKTRQLLLLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERL 64 + N R++ R L +A+ + RAA LN++QPA SK L +LE + G LFER Sbjct: 2 EKNGLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSKTLNELEQLTGTRLFERG 61 Query: 65 PRGMRPTIYGEAMIRHARMALTSLSKAHEDIVALKSGLSGQVDVGGILSPAMALLPPAIA 124 G + T+ GE + HA L +L+ A + + + + V VG + + A+ +LP AI Sbjct: 62 RLGAQLTVPGEQFLTHAVKVLDALNTAGQALNRKEDASADVVRVGALPTAALGILPAAIG 121 Query: 125 RVKEQAPMLRIGVEVESSNILLSRLLHGELDFIIGRILDDEARGGLLYEELADEPICAVA 184 R +Q + V ++ +LL+ L GE+D IGR+ D E GGL YE L E + V Sbjct: 122 RFHQQQKSTSLQVATMNNTMLLAGLKSGEIDLGIGRMSDPELMGGLNYELLFLESLKLVV 181 Query: 185 RVGHPFHARTDLSLADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFIT 244 R GHP T ++L+ + +++PKG++ R + + + QG P+ ++T + Sbjct: 182 RPGHPLLQET-ITLSRVMEWPVVVSPKGTVPRQNAEALLQSQGCKMPAGCIETLSASLSR 240 Query: 245 SLLQQTDFIYAMPTEVARYYTQARLMDILPIELPCRMAG--FGIITRQDNLLSPGANLVL 302 L D+++ +P+ + + + LP+ P + AG GI+TR D LS GA +++ Sbjct: 241 QLTVDYDYVWFVPSGAVKEDLRQATLVSLPV--PTQSAGEPIGILTRVDIPLSTGAQMLI 298 Query: 303 QAIRE 307 AIR+ Sbjct: 299 AAIRK 303 >SMb20580 [K] COG0583 Transcriptional regulator Sme Sinorhizobium meliloti Length = 313 Score = 138 bits (348), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 86/298 (28%), Positives = 156/298 (52%) Query: 12 ARLKTRQLLLLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERLPRGMRPT 71 AR+K R L + + +++ +AA L++TQPA +K +++LE++LGVA+FER RG++ T Sbjct: 4 ARVKFRHLQTFVEVARQKSVVKAAELLHVTQPAVTKTIRELEEVLGVAVFEREGRGIKIT 63 Query: 72 IYGEAMIRHARMALTSLSKAHEDIVALKSGLSGQVDVGGILSPAMALLPPAIARVKEQAP 131 YGE +RHA ALT+L + + + +SG + VG + + + ++P AIA ++ Sbjct: 64 RYGEVFLRHAGAALTALRQGLDSVSQERSGEGPPIRVGALPTVSTRIMPRAIALFLKEKT 123 Query: 132 MLRIGVEVESSNILLSRLLHGELDFIIGRILDDEARGGLLYEELADEPICAVARVGHPFH 191 RI + + +LL +L G+LD ++GR+ + G +E L E + R GHP Sbjct: 124 GARIKIVTGENAVLLEQLRIGDLDLVVGRLAAPDKMTGFSFEHLYSEQVVFAVRAGHPLI 183 Query: 192 ARTDLSLADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFITSLLQQTD 251 + A L+ +M + SI+R + G+A N ++T + F + ++ +D Sbjct: 184 SGRQSLFAHLSDYPVLMPTRASIIRPFVEHFLIANGIAGLPNQIETVSDSFGRAFVRSSD 243 Query: 252 FIYAMPTEVARYYTQARLMDILPIELPCRMAGFGIITRQDNLLSPGANLVLQAIREVA 309 I+ + V ++ LP++ G+ R D + S ++++Q +REVA Sbjct: 244 AIWIISAGVVATDIADGVLAALPVDTSETRGPVGLTMRTDAIPSLPLSILMQTLREVA 301 >ydcI [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 354 Score = 133 bits (335), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 93/306 (30%), Positives = 156/306 (50%), Gaps = 7/306 (2%) Query: 5 DPNWFLRARLKTRQLLLLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERL 64 + N R++ R L +A+ + RAA LN++QPA SK L +LE + G LFER Sbjct: 49 EKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSKTLNELEQLTGARLFERG 108 Query: 65 PRGMRPTIYGEAMIRHARMALTSLSKAHEDIVALKSGLSGQ-VDVGGILSPAMALLPPAI 123 +G + T+ GE + HA L +++ A + K GL+ V VG + + A+ +LP I Sbjct: 109 RQGAQLTLPGEQFLTHAVRVLDAINTAGRSL-HRKEGLNNDVVRVGALPTAALGILPSVI 167 Query: 124 ARVKEQAPMLRIGVEVESSNILLSRLLHGELDFIIGRILDDEARGGLLYEELADEPICAV 183 + +Q + V S+ ++L+ L GE+D IGR+ D E GL YE L E + V Sbjct: 168 GQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSDPELMTGLNYELLFLESLKLV 227 Query: 184 ARVGHPFHARTDLSLADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFI 243 R HP + +++L+ + +++P+G+ R D + + QG PS ++T + Sbjct: 228 VRPNHPL-LQENVTLSRVLEWPVVVSPEGTAPRQHSDALVQSQGCKIPSGCIETLSASLS 286 Query: 244 TSLLQQTDFIYAMPTEVARYYTQARLMDILPIELPCRMAG--FGIITRQDNLLSPGANLV 301 L + D+++ +P+ + + + LP+ P AG GI+TR D S G L+ Sbjct: 287 RQLTVEYDYVWFVPSGAVKDDLRHATLVALPV--PGHGAGEPIGILTRVDATFSSGCQLM 344 Query: 302 LQAIRE 307 + AIR+ Sbjct: 345 INAIRK 350 >STM2180 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 302 Score = 133 bits (334), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 91/287 (31%), Positives = 152/287 (52%), Gaps = 6/287 (2%) Query: 7 NWFLRARLKTRQLLLLIALDDTRNIHRAASELNMTQPAASKQLKDLEDMLGVALFERLPR 66 NW +LK L L+AL + N+ A +N++QPA SK L LED +G+ LFER + Sbjct: 3 NW--AQKLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLSQLEDEIGITLFERHSK 60 Query: 67 GMRPTIYGEAMIRHARMALTSLSKAHEDIVALKSG-LSGQVDVGGILSP-AMALLPPAIA 124 G+RP+ G+ +++HA+ + L ++ +I K G L G + +G SP A + AI Sbjct: 61 GLRPSEGGKLLLQHAQRLINDLERSQYEIARFKQGGLVGSLKIG--CSPVATDCVSQAIL 118 Query: 125 RVKEQAPMLRIGVEVESSNILLSRLLHGELDFIIGRILDDEARGGLLYEELADEPICAVA 184 + + P L + +E + LL LL G++D ++GR+ + L Y+ L EP+C VA Sbjct: 119 SLLNEMPTLHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRALQLPLNYQVLYTEPVCFVA 178 Query: 185 RVGHPFHARTDLSLADLASEAWIMAPKGSILRARCDQMFREQGLAPPSNVVDTTAILFIT 244 R HP AR ++ +DLA WI+ P G+ +R D + G+ P N +++ ++ T Sbjct: 179 RPHHPLAARAQIAWSDLAHWRWIVWPTGTPIRISIDNALVDNGVMLPENTIESASMNVST 238 Query: 245 SLLQQTDFIYAMPTEVARYYTQARLMDILPIELPCRMAGFGIITRQD 291 +LLQ +D I + +A+ Y + IL + + G+ R++ Sbjct: 239 NLLQSSDMISILSLRLAQRYASQGQLAILNLPKIEQKGSVGMFWRKN 285