BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0488.p (359 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC3204 Non COG 285 9e-77 Cgl0816 [E] COG2021 Homoserine acetyltransferase Cgl Corynebacte... 86 1e-16 VNG2420G [E] COG2021 Homoserine acetyltransferase Hbs Halobacter... 86 1e-16 MTH1820 [E] COG2021 Homoserine acetyltransferase Mth Methanother... 83 1e-15 lin0603 [E] COG2021 Homoserine acetyltransferase Lin Listeria in... 81 4e-15 HI1263 [E] COG2021 Homoserine acetyltransferase Hin Haemophilus ... 77 5e-14 CC0525 Non COG 77 8e-14 mlr3538 [E] COG2021 Homoserine acetyltransferase Mlo Mesorhizobi... 75 3e-13 PM0866 [E] COG2021 Homoserine acetyltransferase Pmu Pasteurella ... 69 1e-11 MA2714_1 [E] COG2021 Homoserine acetyltransferase Mac Methanosar... 68 3e-11 >CC3204 Non COG Length = 358 Score = 285 bits (730), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 149/327 (45%), Positives = 201/327 (61%), Gaps = 10/327 (3%) Query: 36 VEGDWVAPRFQFHTGQTLENLRLHYVTLGD-------RANPAVLVLHGTYQSAQAMLSKD 88 EGD V F +G+ L R+ Y T G + AV++LHGT S + LS Sbjct: 31 TEGDLVFKDVTFKSGERLSEARMRYTTAGTPHRNAQGEIDNAVMLLHGTGGSGKNFLSPL 90 Query: 89 FGGQLFGPGQPLDASKYFIIIPDGIGVGKSSKPSDGLRAAFPQYNYADMVLAQYRMLTEG 148 F +LFGPGQPLD +K ++I+PD IG G SSKPSDGLR AFP+Y+Y DM+ Q+R+L EG Sbjct: 91 FADELFGPGQPLDLAKTYVIMPDNIGHGGSSKPSDGLRMAFPRYDYDDMIALQHRLLVEG 150 Query: 149 MGITHLRLIIGNSMGGMQTWIWGGTYPDFADGLVPMASQPTEMASRNWMMRRMLVESIKQ 208 +G+ L+LI+G SMG M ++WG TYP FA+ L P A + RN M R+M +++I+ Sbjct: 151 LGVKRLKLILGTSMGCMHAFVWGQTYPGFAERLAPFACNAVPLVGRNRMWRKMAMDAIRA 210 Query: 209 DPAWNNGNYTTQP-PSLRLANNMFVFATNGGTLAYQAMAGSHAQADKLVDERLAAPV-TA 266 DPAW GNYTTQP LR ++ + A LA QA + DK +D+ A + T Sbjct: 211 DPAWKEGNYTTQPMAGLRTLTDLLILA-GANPLAQQAQYPTREATDKALDQAFNARIGTI 269 Query: 267 DANDFIYQWGSSADYNAAPGLSKIKAPVLAINSADDERNPPETGVMQAALKEVPSAQLLL 326 DAND +Y +S Y+ +PGL KI PVL +NSADD NPPE G+ + K +P A+ +L Sbjct: 270 DANDALYYIDASRTYDPSPGLEKITVPVLWVNSADDFINPPELGLAEPLAKRMPKARFVL 329 Query: 327 IPASAETRGHGTTGMARFYVRELEQFI 353 IPAS ETRGHGT A+F+ +L + + Sbjct: 330 IPASTETRGHGTHTAAKFWKADLAKLL 356 >Cgl0816 [E] COG2021 Homoserine acetyltransferase Cgl Corynebacterium glutamicum Length = 349 Score = 86.3 bits (212), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 88/340 (25%), Positives = 153/340 (45%), Gaps = 42/340 (12%) Query: 44 RFQFHTGQTLENLRLHYVTLG----DRANPAVLV---LHGTYQSAQAMLSKDFGGQLFGP 96 R + G +E+ L Y T G D++N A+L+ GT+Q+ + Q G Sbjct: 22 RLELEEGGVIEDCWLAYATAGTLNEDKSN-AILIPTWYSGTHQT--------WFQQYIGT 72 Query: 97 GQPLDASKYFIIIPDGIGVGKSSKPSDGLR-----AAFPQYNYADMVLAQYRMLTEGMGI 151 LD SKYFII + IG G S P++ + FP D V+AQ R+L + GI Sbjct: 73 DHALDPSKYFIISINQIGNGLSVSPANTADDSISMSKFPNVRIGDDVVAQDRLLRQEFGI 132 Query: 152 THLRLIIGNSMGGMQTWIWGGTYPDFADGLVPMASQPTEMASRNWMMRRMLVESIKQDPA 211 T L ++G SMG QT+ W +PD P+A + +++ + L E+++ DP Sbjct: 133 TELFAVVGGSMGAQQTYEWIVRFPDQVHRAAPIAG-TAKNTPHDFIFTQTLNETVEADPG 191 Query: 212 WNNGNYTTQPP---SLRLANNMFV---FATNGGTLAYQAMAGSHAQADKLVDERLAAPVT 265 +N G Y++ LR ++++ F+T G ++ L D ++ Sbjct: 192 FNGGEYSSHEEVADGLRRQSHLWAAMGFSTEFWKQEAWRRLGLESKESVLADFLDPLFMS 251 Query: 266 ADANDFI-----YQWGSSADY---NAAPGLSKIKAPVLAINSADDERNPPETGVMQAALK 317 D N + +Q G + + + A L ++KA + ++D P + AL Sbjct: 252 MDPNTLLNNAWKWQHGDVSRHTGGDLAAALGRVKAKTFVMPISEDMFFPVRDCAAEQAL- 310 Query: 318 EVPSAQLLLIPASAETRGH-GTTGMARFYVRELEQFIKGL 356 +P ++L +I A GH G ++ Y+ ++++ +K L Sbjct: 311 -IPGSELRVIEDIA---GHLGLFNVSENYIPQIDKNLKEL 346 >VNG2420G [E] COG2021 Homoserine acetyltransferase Hbs Halobacterium sp. NRC-1 Length = 401 Score = 85.9 bits (211), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 58/189 (30%), Positives = 89/189 (47%), Gaps = 21/189 (11%) Query: 45 FQFHTGQTLENLRLHYVTLGD-RANPAVLVLHGTYQSAQAMLSKDFGGQ-----LFGPGQ 98 F F G T+++L + Y T GD + AVLV H S D + + GPG+ Sbjct: 36 FTFACGDTVDSLTVAYRTYGDYTGSNAVLVCHALTGSQHVRGRADGDDRGWWPDIVGPGR 95 Query: 99 PLDASKYFIIIPD--GIGVGKSSKPSDG-----LRAAFPQYNYADMVLAQYRMLTEGMGI 151 P+D ++YF++ + G G P+DG AFP D Q R+L + +G+ Sbjct: 96 PIDTTEYFVVCANVPGSCHGTDGPPADGPGGDPWGTAFPPVTVPDWTRCQRRLL-DTLGV 154 Query: 152 THLRLIIGNSMGGMQTWIWGGTYPDFADGLVPMASQP---TEMASRNWMMRRMLVESIKQ 208 L ++G S+GGM W YPD + +A+ P + N + RR +I+ Sbjct: 155 DRLHAVVGGSVGGMNALDWARRYPDDVHRIAAVATAPRLDAQCLGLNAIARR----AIRG 210 Query: 209 DPAWNNGNY 217 DP WN+G+Y Sbjct: 211 DPNWNDGDY 219 >MTH1820 [E] COG2021 Homoserine acetyltransferase Mth Methanothermobacter thermautotrophicus Length = 319 Score = 82.8 bits (203), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 74/305 (24%), Positives = 131/305 (42%), Gaps = 20/305 (6%) Query: 44 RFQFHTGQTLENLRLHYVTLGDRA-------NPAVLVLHGTYQSAQAMLSKDFGGQLFGP 96 FQF +G+ ++ + Y T G + + AV+ +HG ++ L P Sbjct: 14 EFQFESGEKIQEAPVEYRTTGKPSLDDMGVIDNAVIYIHGWSGDCSSVRRI---AALTEP 70 Query: 97 GQPLDASKYFIIIPDGIGVGKSSKPSD-GLRAAFPQYNYADMVLAQYRMLTEGMGITHLR 155 G L+ +F+I +G S+ PS + FP+Y DMV Q + L E GI +R Sbjct: 71 GGALE--NFFVISISSLGSPGSASPSTTAMGKDFPEYTILDMVNFQRQFLDEKFGIRKVR 128 Query: 156 LIIGNSMGGMQTWIWGGTYPDFADGLVPMASQPTEMASRNWMMRRMLVESIKQDPAWNNG 215 +IG SMGG Q W YPD + L+P+ + ++ N+ + + I+ DP + G Sbjct: 129 GVIGTSMGGFQALQWAAEYPDEMEFLIPLVTS-WQVRGINYALFSYMNHLIEGDPEFRAG 187 Query: 216 NYTTQPPSLRLANNMFVFATNGGTLAYQAMAGSHAQADKLVDERLAAPVTADANDFIYQW 275 T+P +M ++ YQ + + ++ + + + D D I++ Sbjct: 188 ---TRPERALSLASMLMYLHGLSREYYQGLENAELESSMM--DMGSEGALMDPYDVIWRN 242 Query: 276 GSSADYNAAPGLSKIKAPVLAINSADDERNPPETGVMQAALKEVPSAQLLLIPASAETRG 335 ++ ++ + L I+A L D PPE + A + +P A+L+L + G Sbjct: 243 RAAMKHDLSGKLESIRARTLIFGVNQDRYFPPELDTIPMA-QLIPKAELVLFDSECGHLG 301 Query: 336 HGTTG 340 G Sbjct: 302 VNEIG 306 >lin0603 [E] COG2021 Homoserine acetyltransferase Lin Listeria innocua Length = 368 Score = 80.9 bits (198), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 82/299 (27%), Positives = 126/299 (42%), Gaps = 48/299 (16%) Query: 47 FHTGQTLENLRLHYVTLG----DRANPAVL--VLHGTYQSAQAMLSKDFG--GQLFGPGQ 98 G+TL + + Y T G R N +L L GT +A+ G GPG+ Sbjct: 16 LENGETLSPVLVGYETYGTLSASRDNCILLEHALTGTAHAAKHFEDDAPGWWDDYIGPGK 75 Query: 99 PLDASKYFIIIPDGIG-----VGKSS---KPSDGLRAAFPQYNYADMVLAQYRMLTEGMG 150 +D KYF++ + G G SS K + R FP ++ D++ Q R L E +G Sbjct: 76 TIDTDKYFLVCTNVFGGCSGTTGPSSINPKTGEPFRLQFPGFSIKDIIKVQ-RELLEQLG 134 Query: 151 ITHLRLIIGNSMGGMQTWIWGGTYPDFADGLV----PMASQPTEMASRNWMMRRMLVESI 206 +T + +IG SMGGMQ W Y D D ++ P+A+ P + N +MR +I Sbjct: 135 VTRIVSVIGGSMGGMQATEWAIDYADITDSIINIASPLAAGPDAIG-YNLIMRM----AI 189 Query: 207 KQDPAWNNGNYTTQPP----SLRLANNMFVFATNGGTLAYQ----------AMAGSHAQA 252 DP +N GNY QP + R+ M + + ++ A + H Q Sbjct: 190 LNDPDFNGGNYIGQPEGGLATARMVGMMTYRTSELFSKRFERFTVAESSPAAFSKEHFQI 249 Query: 253 DKLVDERLAAPVTA-DANDFIYQWGSSADYNAA-------PGLSKIKAPVLAINSADDE 303 + + + V DAN ++Y + ++ P SKIK P L I D+ Sbjct: 250 ESYLQYQGDTFVERFDANSYLYLTKAIDLFDVTAPAKDDLPAFSKIKIPYLLIGITTDQ 308 >HI1263 [E] COG2021 Homoserine acetyltransferase Hin Haemophilus influenzae Length = 358 Score = 77.0 bits (188), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 58/177 (32%), Positives = 78/177 (44%), Gaps = 19/177 (10%) Query: 60 YVTLGDRANPAVLVLHGTYQSAQAMLSKDFGG---QLFGPGQPLDASKYFIIIPDGIGVG 116 Y TL N AVL+ H A+ G G G LD +YF I + +G Sbjct: 32 YGTLNAEKNNAVLICHALTGDAEPYFDDGRDGWWQNFMGAGLALDTDRYFFISSNVLGGC 91 Query: 117 K------SSKPSDG--LRAAFPQYNYADMVLAQYRMLTEGMGITHLRLIIGNSMGGMQTW 168 K S P G + FP D+V Q + L + +GI+HL+ IIG S GGMQ Sbjct: 92 KGTTGPSSINPQTGKPYGSQFPNIVVQDIVKVQ-KALLDHLGISHLKAIIGGSFGGMQAN 150 Query: 169 IWGGTYPDFADGLVPMASQ---PTEMASRNWMMRRMLVESIKQDPAWNNGNYTTQPP 222 W YPDF D +V + S E N +MR+ ++ DP +N G+Y P Sbjct: 151 QWAIDYPDFMDNIVNLCSSIYFSAEAIGFNHVMRQAVIN----DPNFNGGDYYEGTP 203 >CC0525 Non COG Length = 382 Score = 76.6 bits (187), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 62/206 (30%), Positives = 93/206 (45%), Gaps = 28/206 (13%) Query: 38 GDWVAPR---FQFHTGQTLENLRLHYVTLG----DRANPAVLVLHGTYQSAQAMLSKDFG 90 G W P + +G +E L + Y T G D++N AVL+ H Sbjct: 13 GTWRFPANEPLRLDSGGVIEGLEIAYQTYGQLNADKSN-AVLICHALTGDQHVASPHPTT 71 Query: 91 GQ------LFGPGQPLDASKYFIIIPDGIG----------VGKSSKPSDGLRAAFPQYNY 134 G+ L GPG+PLD +++FII + IG + ++ + GL +FP Sbjct: 72 GKPGWWQRLVGPGKPLDPARHFIICSNVIGGCMGSTGPASINPATGKTYGL--SFPVITI 129 Query: 135 ADMVLAQYRMLTEGMGITHLRLIIGNSMGGMQTWIWGGTYPDFADGLVPMASQPTEMASR 194 ADMV AQ ML +G+ L ++G SMGGMQ W YP+ V +AS + +++ Sbjct: 130 ADMVRAQ-AMLVSALGVETLFAVVGGSMGGMQVQQWAVDYPERMFSAVVLAS-ASRHSAQ 187 Query: 195 NWMMRRMLVESIKQDPAWNNGNYTTQ 220 N + ++I DP W G Y Sbjct: 188 NIAFHEVGRQAIMADPDWRGGAYAEH 213 >mlr3538 [E] COG2021 Homoserine acetyltransferase Mlo Mesorhizobium loti Length = 389 Score = 74.7 bits (182), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 61/217 (28%), Positives = 96/217 (44%), Gaps = 19/217 (8%) Query: 18 AALMLCSAATQAAEPPRPVEGDWVAPRFQFHTGQTLENLRLHYVTLG---DRANPAVLVL 74 AAL +A +P PV + G L ++ Y T G D + A+LV Sbjct: 2 AALRAGKTNNEADQPSSPVLRFGADKPLKLDAGTLLSPFQIAYQTYGTLNDARSNAILVC 61 Query: 75 HGTYQSAQAMLSKDFGGQ------LFGPGQPLDASKYFIIIPDGIG--VGK----SSKPS 122 H + G+ L GPG+ +D +++F+I + IG +G S+ P+ Sbjct: 62 HALTGDQHVANTNPVTGKPGWWEVLIGPGRIIDTNRFFVICSNVIGGCLGSTGPASTNPA 121 Query: 123 DG--LRAAFPQYNYADMVLAQYRMLTEGMGITHLRLIIGNSMGGMQTWIWGGTYPDFADG 180 G P DMV AQ +ML + GI L ++G SMGGMQ W +YP+ Sbjct: 122 TGKPYGLDLPVITIRDMVRAQ-QMLIDHFGIEKLFCVLGGSMGGMQVLEWASSYPERVFS 180 Query: 181 LVPMASQPTEMASRNWMMRRMLVESIKQDPAWNNGNY 217 +P+A+ +S+N + +++ DP W+ G Y Sbjct: 181 ALPIATG-ARHSSQNIAFHEVGRQAVMADPDWHGGKY 216 >PM0866 [E] COG2021 Homoserine acetyltransferase Pmu Pasteurella multocida Length = 360 Score = 68.9 bits (167), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 24/202 (11%) Query: 45 FQFHTGQTLENLRLHYVTLGD---RANPAVLVLHGTYQSAQAMLS----KDFGGQLFGPG 97 F G TL+++ + Y T G+ A+L+ H A+ + + + G G Sbjct: 14 FTLSLGGTLQDIEIAYQTYGELNKEKTNAILICHALTGDAEPYFADHSQRGWWQTFMGEG 73 Query: 98 QPLDASKYFIIIPDGIGVGKSS--------KPSDGLRAAFPQYNYADMVLAQYRMLTEGM 149 LD S+YF I + +G K + K + + FP D+V Q +LT + Sbjct: 74 LALDTSQYFFICSNVLGGCKGTTGPSSINPKTNKPYGSQFPNIIVQDIVALQRALLTH-L 132 Query: 150 GITHLRLIIGNSMGGMQTWIWGGTYPDFADGLVPMASQ---PTEMASRNWMMRRMLVESI 206 I L +IG S GGMQ W YPD ++ + S E N +MR+ ++ Sbjct: 133 NIPRLHAVIGGSFGGMQATQWAIDYPDDVSNVINLCSSLLFGAEAIGFNHVMRQAVI--- 189 Query: 207 KQDPAWNNGN-YTTQPPSLRLA 227 DP +N G+ Y +QPP LA Sbjct: 190 -NDPNFNGGDYYDSQPPEKGLA 210 >MA2714_1 [E] COG2021 Homoserine acetyltransferase Mac Methanosarcina acetivorans str.C2A Length = 419 Score = 68.2 bits (165), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 57/202 (28%), Positives = 89/202 (44%), Gaps = 22/202 (10%) Query: 45 FQFHTGQTLENLRLHYVTLG----DRANPAVLVLHGTYQSAQAMLSKDFGGQ------LF 94 F +G+TL +R+ Y G D++N +L+ H A A + + + Sbjct: 39 FGLESGKTLSGVRVEYEMYGKMNADKSN-VILICHALTGDAHAAGFHEGDKKPGWWEIVI 97 Query: 95 GPGQPLDASKYFIIIPDGIGVGKSS------KPSDGLR--AAFPQYNYADMVLAQYRMLT 146 GP + D KY +I + +G K S P G +FP DMV AQ + L Sbjct: 98 GPNKAFDTEKYCVICSNILGGCKGSTGPSSIDPETGKHYGISFPVITVKDMVNAQ-KKLI 156 Query: 147 EGMGITHLRLIIGNSMGGMQTWIWGGTYPDFADGLVPMASQPTEMASRNWMMRRMLVESI 206 E +G+ L + G SMGGMQ W +YP+ + +A+ + + + ++I Sbjct: 157 EHLGVKQLFAVAGGSMGGMQVLQWTVSYPEMVRKAIAIATTAS-TTPQQIAFGAIGRKAI 215 Query: 207 KQDPAWNNGNYT-TQPPSLRLA 227 DP WN G+Y + PS LA Sbjct: 216 TDDPKWNGGDYYGKEIPSQGLA 237