BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0444.p (281 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc00270 [G] COG3959 Transketolase, N-terminal subunit Sme Sinor... 414 e-115 mll5765 Non COG 388 e-108 TM0954 [G] COG3959 Transketolase, N-terminal subunit Tma Thermot... 198 1e-50 FN0294 [G] COG3959 Transketolase, N-terminal subunit Fnu Fusobac... 192 1e-48 SP2128 [G] COG3959 Transketolase, N-terminal subunit Spn Strepto... 177 2e-44 MJ0681 [G] COG3959 Transketolase, N-terminal subunit Mja Methano... 174 2e-43 STM2341 [G] COG3959 Transketolase, N-terminal subunit Sty Salmon... 173 3e-43 TVN0668 [G] COG3959 Transketolase, N-terminal subunit Tvo Thermo... 160 2e-39 AGc3490 [G] COG3959 Transketolase, N-terminal subunit Atu Agroba... 155 7e-38 YPO3314 [G] COG3959 Transketolase, N-terminal subunit Ype Yersin... 155 1e-37 >SMc00270 [G] COG3959 Transketolase, N-terminal subunit Sme Sinorhizobium meliloti Length = 284 Score = 414 bits (1063), Expect = e-115, Method: Compositional matrix adjust. Identities = 197/266 (74%), Positives = 227/266 (85%) Query: 7 NLRASAYRIRRNAVRMGEVQGQGYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDRFLL 66 +L A+ IRR AVRMGEVQGQGY+GQALG ADVLAV+Y HA++ R DP+W GRDRFLL Sbjct: 14 SLARRAWEIRRKAVRMGEVQGQGYVGQALGIADVLAVSYFHALTYRRQDPEWEGRDRFLL 73 Query: 67 SHGHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMATYTPGMEISGGSLGQGLAIG 126 S GHYAIALYAALIEAGI+P++EL++YG+DDSRLPMSGMA YTPGMEI+GGSLGQGL IG Sbjct: 74 SIGHYAIALYAALIEAGILPEQELETYGTDDSRLPMSGMAAYTPGMEITGGSLGQGLGIG 133 Query: 127 VGMALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDINNQQADGPS 186 VGMALGL+ NPAFVYN MSDGEL EGSTWEAAM AAHH++GNLICLVD N+QQADG S Sbjct: 134 VGMALGLKAKKNPAFVYNLMSDGELGEGSTWEAAMSAAHHKLGNLICLVDFNDQQADGKS 193 Query: 187 GKIMGFEPLADKWAAFGWYVQRVDGNDLAAVVQAFDNARNLKDAKPRVILFDTLMGKGVP 246 +++ EPL KWAAFGW+VQRVDGND+ A+V AFD AR L++A PRVI+ DTLM KGVP Sbjct: 194 TEMLCSEPLGAKWAAFGWHVQRVDGNDIPALVAAFDAARALEEAMPRVIICDTLMCKGVP 253 Query: 247 FLEQREKNHFIRVDPPEWQQALSILD 272 FLEQRE HF+RVD EWQ+AL+ LD Sbjct: 254 FLEQREVTHFVRVDADEWQKALAALD 279 >mll5765 Non COG Length = 279 Score = 388 bits (997), Expect = e-108, Method: Compositional matrix adjust. Identities = 185/271 (68%), Positives = 217/271 (80%) Query: 7 NLRASAYRIRRNAVRMGEVQGQGYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDRFLL 66 +L AYRIRR+AVRMGEVQGQGY+GQALG ADVLAVAY HA+ RPDD W GRDRFLL Sbjct: 9 SLAERAYRIRRHAVRMGEVQGQGYVGQALGVADVLAVAYFHALRYRPDDTLWEGRDRFLL 68 Query: 67 SHGHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMATYTPGMEISGGSLGQGLAIG 126 S GHYAIALYAALIEAG++P+EEL++YG+DDSR+PMSGMA YTPGMEI+GGSLG GL I Sbjct: 69 SIGHYAIALYAALIEAGVLPEEELETYGTDDSRMPMSGMAAYTPGMEITGGSLGHGLGIA 128 Query: 127 VGMALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDINNQQADGPS 186 VGM LGL+ + FVYN +SDGEL EGSTWEAAM AAHH++ NLI +VD NN QADGPS Sbjct: 129 VGMCLGLKRKQSDCFVYNLLSDGELGEGSTWEAAMSAAHHKLDNLIAIVDFNNLQADGPS 188 Query: 187 GKIMGFEPLADKWAAFGWYVQRVDGNDLAAVVQAFDNARNLKDAKPRVILFDTLMGKGVP 246 ++ EP+ DK+ AFGW+ QRVDGND+ A+ AFDNAR LKD +PR+I+ DT M KGVP Sbjct: 189 TAMLSSEPVTDKFEAFGWHAQRVDGNDIEALRAAFDNARGLKDPRPRIIVCDTRMAKGVP 248 Query: 247 FLEQREKNHFIRVDPPEWQQALSILDQSYQQ 277 FLE R+ HFIRV+P EW AL L++ Q Sbjct: 249 FLEARDITHFIRVEPYEWALALEALEKGRPQ 279 >TM0954 [G] COG3959 Transketolase, N-terminal subunit Tma Thermotoga maritima Length = 286 Score = 198 bits (503), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 105/274 (38%), Positives = 159/274 (58%), Gaps = 4/274 (1%) Query: 4 NLANLRASAYRIRRNAVRMGEVQGQGYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDR 63 + L+ A IR+ + M G+ G +L ++L + + ++P+DP W RDR Sbjct: 8 EVLELKRKAIEIRKMILDMIYKAKSGHTGGSLSSVEILVTLFYKILRVKPEDPNWEDRDR 67 Query: 64 FLLSHGHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMAT-YTPGMEISGGSLGQG 122 F+LS GH A YA L + G P EEL++Y SRL +G T PG+E++ G+LG G Sbjct: 68 FILSKGHSVEAYYAVLADKGFFPKEELETYCKYGSRL--TGHPTRKVPGVEVNTGALGHG 125 Query: 123 LAIGVGMALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDINNQQA 182 LAIGVGMAL + + VY M DGELDEGS WEAA A+H+ + NLI +VD N Q Sbjct: 126 LAIGVGMALAGKMDGKDYKVYVLMGDGELDEGSVWEAAQVASHYSLDNLIGIVDRNRLQI 185 Query: 183 DGPSGKIMGFEPLADKWAAFGWYVQRVDGNDLAAVVQAFDNARNLKDAKPRVILFDTLMG 242 G + +++ EPL+ +W AFGW V VDG+D ++ + F + + KP +I+ +T+ G Sbjct: 186 SGHTEEVLKLEPLSKRWEAFGWNVLEVDGHDFESLYKTFVSIPR-ETGKPHLIIANTIKG 244 Query: 243 KGVPFLEQREKNHFIRVDPPEWQQALSILDQSYQ 276 KG+ F+E R + H E+++A+ L++ + Sbjct: 245 KGISFIEGRVEWHHKVPSDEEYRKAIEELEEQLK 278 >FN0294 [G] COG3959 Transketolase, N-terminal subunit Fnu Fusobacterium nucleatum Length = 270 Score = 192 bits (487), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 107/268 (39%), Positives = 150/268 (55%), Gaps = 1/268 (0%) Query: 4 NLANLRASAYRIRRNAVRMGEVQGQGYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDR 63 +++ L+ A IR++ V M G+ G +L D+L Y M++ P +P+ GRDR Sbjct: 3 DISFLKEKAKEIRKSIVSMIAEAKSGHPGGSLSATDILTALYFSEMNVDPTNPKMEGRDR 62 Query: 64 FLLSHGHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMATYTPGMEISGGSLGQGL 123 F+LS GH A A+YA L E G +EL + SRL G+EIS GSLGQGL Sbjct: 63 FVLSKGHAAPAIYATLAEKGYFSKDELMTLRKFGSRLQGHPDMKKLSGIEISTGSLGQGL 122 Query: 124 AIGVGMALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDINNQQAD 183 ++ GMAL + + Y + DGE+ EG WEAAM AAH+++ NL +D NN Q D Sbjct: 123 SVANGMALNAKIFDENYRTYVVLGDGEIQEGQIWEAAMTAAHYKLDNLCAFLDSNNLQID 182 Query: 184 GPSGKIMGFEPLADKWAAFGWYVQRVDGNDLAAVVQAFDNARNLKDAKPRVILFDTLMGK 243 G +I G EPL KW AFGW V ++DG+D ++ A + AR K KP +I+ T+ GK Sbjct: 183 GNVTEIKGVEPLDKKWEAFGWNVIKIDGHDFEQILSALEKARECK-GKPTMIIAKTIKGK 241 Query: 244 GVPFLEQREKNHFIRVDPPEWQQALSIL 271 GV F+E H + E ++AL+ L Sbjct: 242 GVSFMENVCGFHGVAPTVEELERALAEL 269 >SP2128 [G] COG3959 Transketolase, N-terminal subunit Spn Streptococcus pneumoniae TIGR4 Length = 285 Score = 177 bits (449), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 96/270 (35%), Positives = 147/270 (54%) Query: 8 LRASAYRIRRNAVRMGEVQGQGYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDRFLLS 67 LR A IR N +R G G+ G +L +VLAV Y M + P+ RD F+LS Sbjct: 11 LRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVLAVLYGEIMPMTPEIFAARDRDYFILS 70 Query: 68 HGHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMATYTPGMEISGGSLGQGLAIGV 127 GH ALY+ L G E L S ++ ++LP TPG++++ GSLGQG+++ Sbjct: 71 KGHGGPALYSTLYLNGFFDKEFLYSLNTNGTKLPSHPDRNLTPGIDMTTGSLGQGISVAT 130 Query: 128 GMALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDINNQQADGPSG 187 G+A G R +P + Y + DGEL+EG WEA A+H Q+ NLI VD N +Q DG + Sbjct: 131 GLAYGQRIRKSPFYTYAIVGDGELNEGQCWEAIQFASHQQLSNLIVFVDDNKKQLDGFTK 190 Query: 188 KIMGFEPLADKWAAFGWYVQRVDGNDLAAVVQAFDNARNLKDAKPRVILFDTLMGKGVPF 247 I +K++AFG+ RV G+D+ + + + ++ P+ I+ DT+ G+GV Sbjct: 191 DICNPGDFVEKFSAFGFESIRVKGSDIREIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQE 250 Query: 248 LEQREKNHFIRVDPPEWQQALSILDQSYQQ 277 LE+ + NH +R E Q S++++ Q+ Sbjct: 251 LEEMKSNHHLRPTVEEKQMLTSVVERLSQE 280 >MJ0681 [G] COG3959 Transketolase, N-terminal subunit Mja Methanococcus jannaschii Length = 274 Score = 174 bits (442), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 106/275 (38%), Positives = 156/275 (56%), Gaps = 3/275 (1%) Query: 1 MSDNL--ANLRASAYRIRRNAVRMGEVQGQGYIGQALGWADVLAVAYKHAMSLRPDDPQW 58 M +NL +L A ++R N V+M + G+ G +L D++ Y M+ PD+P Sbjct: 1 MDNNLEIKDLEKIAKKVRYNIVKMVGLAKSGHPGGSLSATDIIVALYFKLMNYSPDNPYK 60 Query: 59 SGRDRFLLSHGHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMATYTPGMEISGGS 118 RDRF+LS GH A ALYA L E GI+ +EEL + +L + TPG+EI GS Sbjct: 61 KDRDRFVLSKGHAAPALYAVLSELGIIEEEELWKLRRLEGKL-QGHPSMDTPGVEICTGS 119 Query: 119 LGQGLAIGVGMALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDIN 178 LGQG + VGMALG R + +VY + DGE EG WEAAM AAH+++ NLI +D N Sbjct: 120 LGQGFSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEAAMAAAHYKLDNLIAFIDRN 179 Query: 179 NQQADGPSGKIMGFEPLADKWAAFGWYVQRVDGNDLAAVVQAFDNARNLKDAKPRVILFD 238 Q DG + +M + K+ AFGW V +DG++ ++ + A+++K+ KP++I+ Sbjct: 180 KLQIDGCTEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSMKNGKPKMIIAY 239 Query: 239 TLMGKGVPFLEQREKNHFIRVDPPEWQQALSILDQ 273 T+ GKGV F+E H + + +QAL L + Sbjct: 240 TVKGKGVSFMENNVAFHGKAPNEEQLKQALEELSE 274 >STM2341 [G] COG3959 Transketolase, N-terminal subunit Sty Salmonella typhimurium LT2 Length = 276 Score = 173 bits (439), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 101/259 (38%), Positives = 143/259 (55%), Gaps = 7/259 (2%) Query: 4 NLANLRASAYRIRRNAVRMGEVQGQGYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDR 63 N+ + A IR ++ G G+ G ++ + LAV Y M + P DP W RD Sbjct: 2 NVTEITQLARDIRVATLKSLNHLGFGHYGGSMSVVETLAVLYGAVMKIDPADPDWPERDY 61 Query: 64 FLLSHGHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMATYTPGMEISGGSLGQGL 123 F+LS GH ALY+ L G P EEL++ + +RLP T G++ + GSLGQG+ Sbjct: 62 FVLSKGHAGPALYSTLAIKGYFPREELNTLNQNGTRLPSHPDRLKTRGVDATTGSLGQGI 121 Query: 124 AIGVGMALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDINNQQAD 183 +I GMAL + P V+ + DGEL+EG WEA AHH++ NL +D N QQ D Sbjct: 122 SIAGGMALSHKLARRPNRVFCIVGDGELNEGQCWEAFQFIAHHRLNNLTVFIDWNKQQLD 181 Query: 184 GPSGKIMGFEPLADKWAAFGWYVQRVDGNDLA---AVVQAFDNARNLKDAKPRVILFDTL 240 G +I+ L K+ AFG+ V V G+D+A AVVQ A DA+PRV++ D++ Sbjct: 182 GELEEIINPFDLEGKFRAFGFDVVTVKGDDIAGLLAVVQPVPPA----DAQPRVVILDSI 237 Query: 241 MGKGVPFLEQREKNHFIRV 259 G+GVP LEQ +H +R+ Sbjct: 238 KGQGVPCLEQLTNSHHLRL 256 >TVN0668 [G] COG3959 Transketolase, N-terminal subunit Tvo Thermoplasma volcanium Length = 273 Score = 160 bits (406), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 96/261 (36%), Positives = 140/261 (53%), Gaps = 8/261 (3%) Query: 7 NLRASAYRIRRNAVRMGEVQGQGYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDRFLL 66 +L A +IRR +RM G+ G +L D+L V Y M++ P+ P+ RDR +L Sbjct: 7 DLSDIALKIRREIIRMVYNAQSGHPGGSLSVTDILTVLYFKEMNIDPNKPKDPKRDRLIL 66 Query: 67 SHGHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMATY-TPGMEISGGSLGQGLAI 125 S GH + ALYA L G P +L + DS L G T PG+E+S GSLGQGL I Sbjct: 67 SKGHASPALYATLAIRGFFPVSDLSGFRKLDSHL--EGHVTREVPGVEVSTGSLGQGLGI 124 Query: 126 GVGMALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDINNQQADGP 185 GVGMAL R + VY + DGE++EG+ WE+ M + + N+ ++D N Q DG Sbjct: 125 GVGMALAGRLDGMQYRVYVILGDGEMEEGNVWESLMAGYKYNLNNITAILDKNGIQLDGY 184 Query: 186 SGKIMGFEPLADKWAAFGWYVQRVDGNDLAAVVQAFDNARNLKDAKPRVILFDTLMGKGV 245 + IM + +FGW V +DG++ + +A ++N +P I+ +T+ GKGV Sbjct: 185 TKDIMPMHDIKSMVESFGWNVIEIDGHNYDQIHEAVQASKN--SDRPTFIIANTVKGKGV 242 Query: 246 PFLEQREKNHFIRVDPPEWQQ 266 F+E K H PPE ++ Sbjct: 243 DFMENNPKYHG---SPPESKE 260 >AGc3490 [G] COG3959 Transketolase, N-terminal subunit Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 269 Score = 155 bits (393), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 89/266 (33%), Positives = 135/266 (50%), Gaps = 10/266 (3%) Query: 14 RIRRNAVRMGEVQ-----GQGYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDRFLLSH 68 RI R +R+ +VQ G G++G + D++ Y + + P+DP+ RDRF+LS Sbjct: 8 RIARQ-IRLRDVQAVFEAGAGHVGGEMSAIDIMTALYFRVLRIWPNDPKNPARDRFVLSK 66 Query: 69 GHYAIALYAALIEAGIVPDEELDSYGSDDSRLPMSGMATYTPGMEISGGSLGQGLAIGVG 128 GH A ALY L + G +P+EE+ ++ +SRL PG+E + G LG GL + VG Sbjct: 67 GHTACALYVTLAKRGFIPEEEISTFLQPNSRLNGHPNCNKVPGVETNTGPLGHGLPVAVG 126 Query: 129 MALGLRYNNNPAFVYNSMSDGELDEGSTWEAAMGAAHHQMGNLICLVDINNQQADGPSGK 188 MA + + Y DGE+ EGS WEA M AA ++ NL ++D N Q Sbjct: 127 MATAAKLSGEDYHTYVMTGDGEMQEGSNWEAIMSAAQFKLNNLTLVIDHNRFQQGAAIAD 186 Query: 189 IMGFEPLADKWAAFGWYVQRVDGNDLAAVVQAFDNARNLKDAKPRVILFDTLMGKGVPFL 248 PL K AFGW V ++GN +A VV A ++ N +P I+ T G G+ F+ Sbjct: 187 TNDVAPLRPKLEAFGWEVTEINGNAMAEVVPALEHRGN----RPHCIVAHTNKGHGISFM 242 Query: 249 EQREKNHFIRVDPPEWQQALSILDQS 274 + R H +++ A+ L ++ Sbjct: 243 QDRVDWHHKVPSKEQYEIAVKELSEA 268 >YPO3314 [G] COG3959 Transketolase, N-terminal subunit Ype Yersinia pestis Length = 276 Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 85/227 (37%), Positives = 125/227 (55%), Gaps = 2/227 (0%) Query: 29 GYIGQALGWADVLAVAYKHAMSLRPDDPQWSGRDRFLLSHGHYAIALYAALIEAGIVPDE 88 G+ G L ++L Y ++ P+ RD ++ S GH Y L EA P+E Sbjct: 33 GHTGADLSQVEILTALYFRILNCAPERLTDPERDIYVQSKGHAVGGYYCCLAEARYFPEE 92 Query: 89 ELDSYGSDDSRLPMSGMATYTPGMEISGGSLGQGLAIGVGMALGLRYNNNPAFVYNSMSD 148 L +Y DS LP + TPG+E++ G+LG GL + VG+AL + N+ V+ D Sbjct: 93 WLATYQRADSHLPGHPVKHKTPGIELNTGALGHGLPVAVGIALAAKRANSKRRVFVLTGD 152 Query: 149 GELDEGSTWEAAMGAAHHQMGNLICLVDINNQQADGPSGKIMGFEPLADKWAAFGWYVQR 208 GEL EGS WEAA+ AAH+Q+ NL+ + D N Q G + IM +PLADKW AFG V Sbjct: 153 GELAEGSNWEAALVAAHYQLDNLVIINDKNKLQLAGTTKSIMNTDPLADKWRAFGLQVTE 212 Query: 209 VDGNDLAAVVQAFDNARNLKDAKPRVILFDTLMGKGVPFLEQREKNH 255 GND+ +VV+ + ++ KP V++ +T G G+ F++ R + H Sbjct: 213 CRGNDMQSVVETLETLP--QNGKPNVVIANTEKGAGISFIQGRVEWH 257