BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0433.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 303 8e-82 RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 285 1e-76 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 279 1e-74 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 258 2e-68 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 258 3e-68 STM2179 [GEPR] COG0477 Permeases of the major facilitator superf... 238 2e-62 PA2006 [GEPR] COG0477 Permeases of the major facilitator superfa... 232 1e-60 PA2472 [GEPR] COG0477 Permeases of the major facilitator superfa... 230 4e-60 PA4900 [GEPR] COG0477 Permeases of the major facilitator superfa... 225 1e-58 Cgl2334 [GEPR] COG0477 Permeases of the major facilitator superf... 187 6e-47 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 303 bits (775), Expect = 8e-82, Method: Compositional matrix adjust. Identities = 178/429 (41%), Positives = 251/429 (58%), Gaps = 6/429 (1%) Query: 10 PTVHVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPV 69 P + V +++ RF AFQ+ ++LLC + IDGFD +G++APA+ DW + A LG V Sbjct: 6 PVIDVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGTV 65 Query: 70 FGAGLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGF 129 F AGL G+++G+L+ P+ DR GR+ L+ + F L + + ++ L+ LRF+TG Sbjct: 66 FSAGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTGL 125 Query: 130 GLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVG 189 GLG MPNA+AL E+ P R ++ CGFT+G+ GG V+A L+P +GW +V G Sbjct: 126 GLGGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLFG 185 Query: 190 GAVPLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVVKETKAEG 249 G +PL+L M+ LPES+++LV V R L ++ P V D T V+ ET A+G Sbjct: 186 GVIPLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPD-TRFVLHETAAKG 244 Query: 250 M---PVAALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSL 306 PV LF T+LLW + FM+L+ +Y ++NWLPTLI G + ++A I Sbjct: 245 APGSPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVMY 304 Query: 307 QVGGVIGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIV 366 Q+GG +G L +GR + R+ T VL + L + L G + +L +AV GFCI Sbjct: 305 QLGGTVGALVIGRMMDRYPATVVLCCTYGLGAGFLVLTG--VSQGTMLAIAVTGVGFCIS 362 Query: 367 GGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAV 426 G Q NA A FYPT R TGI WALGIGR+GSV G +IGG L+A LFL AV Sbjct: 363 GSQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLLVAV 422 Query: 427 PALISALTI 435 PA I++L I Sbjct: 423 PAAIASLAI 431 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 285 bits (730), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 175/428 (40%), Positives = 244/428 (57%), Gaps = 12/428 (2%) Query: 8 ALP---TVHVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKA 64 ALP V V +V++ R A+Q +L LC ++DGFD A+GY+APA+ W ++ Sbjct: 3 ALPARADVPVREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLTPP 62 Query: 65 SLGPVFGAGLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLR 124 L P FGAGLFG++LGS+ L PV DR+GR+PVL++S L F + LA +L+ L++LR Sbjct: 63 QLAPAFGAGLFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLR 122 Query: 125 FITGFGLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHA 184 F+TG GLG MP + L E+SP R+ + L GFT G A GG V+A ++P YGW Sbjct: 123 FLTGLGLGGAMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRG 182 Query: 185 VFWVGGAVPLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVV-- 242 V GG PLVL + +W+PES+QFL +RP Q A LR++ I D + V Sbjct: 183 VLVAGGVTPLVLLPVLALWMPESVQFLA--QRP--QCADALRQIVTRIAGHDHGDGVTFI 238 Query: 243 -KETKAEGMPVAA--LFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMA 299 EG P LF DG A TVLLW F +L Y L++WLP ++RD G + + A Sbjct: 239 GDRPAQEGAPFPGRNLFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEA 298 Query: 300 VLIGTSLQVGGVIGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVI 359 +G + +GG IG ++L + R G R L + + +++A IG A L V Sbjct: 299 ARVGAMVPLGGTIGAIALALLMDRAGSPRALIAAYFCGAIAVAAIGLAIGNVAALTAVVF 358 Query: 360 VAGFCIVGGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNAS 419 V GF I G Q +N LA YPT R+TG+ WALG+GR GS+ G ++GG L+ + + Sbjct: 359 VVGFGIAGAQNGINLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGSVQT 418 Query: 420 LFLAAAVP 427 LF A+P Sbjct: 419 LFGIIALP 426 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 279 bits (713), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 171/416 (41%), Positives = 250/416 (60%), Gaps = 4/416 (0%) Query: 5 TSGALPTVH---VDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGV 61 S +LP V V + +Q+ ++LLC L + +DG D AMG++APA+ DWG+ Sbjct: 2 NSPSLPAVERLDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGI 61 Query: 62 SKASLGPVFGAGLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLL 121 +ASLGPV A L GM+ G+L P+ DRYGR+ VL+ + F L LA+ T ++QLL Sbjct: 62 DRASLGPVMSAALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLL 121 Query: 122 VLRFITGFGLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYG 181 LRF+TG GLG+ MPNA L+ E++P + + + CGF +G A GGFVSA LIP +G Sbjct: 122 ALRFLTGLGLGAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFG 181 Query: 182 WHAVFWVGGAVPLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVV 241 WH++ +GG +PLVL + +L LPES ++LV+ R +V + L + P V ++ V Sbjct: 182 WHSLLLLGGLLPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFHV 241 Query: 242 VKETKAEGMPV-AALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAV 300 ++ + V A +F + T+LLWL FM L+ +Y L++WLPTL+RD+G S A Sbjct: 242 PEQQTVQARNVFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAA 301 Query: 301 LIGTSLQVGGVIGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIV 360 IG Q GGV+ +++G + RF +V+G +LLA + +G+ LL V++ Sbjct: 302 FIGALFQFGGVLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSLGQVTLLATLVLL 361 Query: 361 AGFCIVGGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWT 416 AG CI G Q A+ +LA FYPT R+TG+ W LGIGR G+++G IG L+ L W Sbjct: 362 AGMCINGAQSAMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLGWN 417 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 258 bits (659), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 151/426 (35%), Positives = 248/426 (58%), Gaps = 1/426 (0%) Query: 13 HVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGA 72 + +++ G Q+ +++ C L +++DGFD A+G++AP I W ++ L P+FGA Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGA 65 Query: 73 GLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGFGLG 132 GL G+ G+L+ P+ DR+GR+ V+ L F LA+ L L+ LRF+TG GLG Sbjct: 66 GLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 133 SIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVGGAV 192 MPN + + E+ P+ R + L+ CGFT+G+A GG VSA L+P GWH + +GG + Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 193 PLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVVKETKAEGMPV 252 PL+L +A+LV LPES ++ V + P+ +A+ + + +D ++ + +G + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKG-SI 244 Query: 253 AALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSLQVGGVI 312 LF + +T++LW++ FM+L+ +Y LS+W+PTL+ G A + + Q+GG + Sbjct: 245 RQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTL 304 Query: 313 GTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIVGGQPAV 372 G L+LG + +F RVL + + + I +IG L+ +A+ G I G Q + Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 373 NALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAVPALISA 432 NAL T YPT R+TG+ W+ IGR G++VG + GG ++A+ ++ +LF AVPA ISA Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 433 LTIARL 438 + + L Sbjct: 425 VMLTLL 430 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 258 bits (658), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 150/426 (35%), Positives = 247/426 (57%), Gaps = 1/426 (0%) Query: 13 HVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGA 72 + +++ G Q+ +++ C L +++DGFD A+G++AP I W ++ L P+FGA Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFGA 65 Query: 73 GLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGFGLG 132 GL + G+L+ P+ DR+GR+ V+ L F LA+ L L+ LRF+TG GLG Sbjct: 66 GLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 133 SIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVGGAV 192 MPN + + E+ P+ R + L+ CGFT+G+A GG VSA L+P GWH + +GG + Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 193 PLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVVKETKAEGMPV 252 PL+L +A+LV LPES ++ V + P+ +A+ + + +D ++ + +G + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKG-SI 244 Query: 253 AALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSLQVGGVI 312 LF + +T++LW++ FM+L+ +Y LS+W+PTL+ G A + + Q+GG + Sbjct: 245 RQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTL 304 Query: 313 GTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIVGGQPAV 372 G L+LG + +F RVL + + + I +IG L+ +A+ G I G Q + Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 373 NALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAVPALISA 432 NAL T YPT R+TG+ W+ IGR G++VG + GG ++A+ ++ +LF AVPA ISA Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 433 LTIARL 438 + + L Sbjct: 425 VMLTLL 430 >STM2179 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 452 Score = 238 bits (607), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 155/427 (36%), Positives = 245/427 (57%), Gaps = 3/427 (0%) Query: 13 HVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGA 72 + +++ G Q+ +++ C L +++DGFD A+G++AP I W +S + L P+FGA Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLSASELAPLFGA 65 Query: 73 GLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGFGLG 132 GL G+ G+L+ P+ DR+GR+ V+ L F L + ++ L++LRF+TG GLG Sbjct: 66 GLLGLTAGALLCGPLADRFGRKRVIELCVALFGALSLLSAFSPDIETLVLLRFLTGLGLG 125 Query: 133 SIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVGGAV 192 MPN + + E+ P+ R + L+ CGFT+G+A GG VSA L+P GWH + +GG + Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAMGGIVSAQLVPLIGWHGILALGGIL 185 Query: 193 PLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVVKETKAEGM-P 251 PL+L +L LPES ++ V + P+ VAR + + D T+ + ET A Sbjct: 186 PLMLFFGLLFALPESPRWQVRRQLPQAVVARTVSAITGERYHD--TQFFLHETAAVAKGS 243 Query: 252 VAALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSLQVGGV 311 + LF + +T++LW++ FM+L+ +Y LS+W+PTL+ G A + + QVGG Sbjct: 244 IRQLFAGRQLVITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQQASWVTAAFQVGGT 303 Query: 312 IGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIVGGQPA 371 +G L LG + R RVL + L + I +IG L+ +A+ G I G Q Sbjct: 304 LGALLLGVLMDRLNPFRVLAVSYALGAVCIVMIGLSENGLWLMALAIFGTGIGISGSQVG 363 Query: 372 VNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAVPALIS 431 +NAL T YPT R+TG+ W+ IGR G++VG + GG ++AL ++ +LF A+PA IS Sbjct: 364 LNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGMMMALNFSFDTLFFVIAIPAAIS 423 Query: 432 ALTIARL 438 A+ + L Sbjct: 424 AVMLTLL 430 >PA2006 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 450 Score = 232 bits (592), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 157/405 (38%), Positives = 237/405 (58%), Gaps = 4/405 (0%) Query: 39 IIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGAGLFGMLLGSLVLTPVGDRYGRRPVLI 98 + DG+D Q +GYV P + +WG+ KA+ GPVF A LFG+ +GSL++TP+ DR+G R VL+ Sbjct: 33 VTDGYDAQVLGYVVPTLAQEWGLDKAAFGPVFSANLFGLTVGSLLVTPLADRFGIRRVLL 92 Query: 99 LSTLFFALCMLATPMVTTLDQLLVLRFITGFGLGSIMPNAMALVGEFSPSSSRVTRMMLV 158 L +A + +L+ L++ RF+ G G+G MP+AMAL+ E+SP R + L Sbjct: 93 CCVLIYASLTVLMVFAGSLESLMLARFVCGIGMGGAMPSAMALMAEYSPPRLRTLMVTLA 152 Query: 159 SCGFTVGAAAGGFVSAALIPAYGWHAVFWVGGAVPLVLGLAMLVWLPESIQFLVLHRRPR 218 +CGF+ G AAGGFV+AA + +GW AVF GG PL+L +L++LPES+ L+ P Sbjct: 153 ACGFSFGGAAGGFVAAAFMDGFGWQAVFLAGGVTPLLLFPFLLLFLPESLPRLLRDAPPY 212 Query: 219 TQVARWLRKLDPNIVIDDKTEVVVKETKAEGMPVAALFRDGRAGVTVLLWLISFMNLINL 278 ++ + ++ P A + V LFR G A T+LLW F++LI L Sbjct: 213 ARLRQLSERMAPGW---QPPPAEADAEPAASLTVLELFRHGYARPTLLLWATFFVSLILL 269 Query: 279 YFLSNWLPTLIRDAGYSTSMAVLIGTSLQVGGVIGTLSLGRFIQRF-GFTRVLGSCFLLA 337 YF+ +WLP+L++++G + + A L + G +G + L R R+L + A Sbjct: 270 YFMVSWLPSLLQESGLTRNAANLATSMFLFAGTLGAMLLAWLADRLRSKVRLLAAILAGA 329 Query: 338 CLSIALIGKLATVPALLFVAVIVAGFCIVGGQPAVNALAGTFYPTTLRSTGIGWALGIGR 397 L L+G P L V AGFCI+GGQ +NA A FYP +R+TG GWALG+GR Sbjct: 330 ALFTLLLGLNHDQPRWLLAFVFAAGFCIIGGQLTLNAFASNFYPAQVRATGTGWALGVGR 389 Query: 398 IGSVVGPVIGGQLIALQWTNASLFLAAAVPALISALTIARLHRTA 442 GS++GP+ G L+ + + ++F+ AA+PA ++AL I ++ A Sbjct: 390 FGSILGPLFGSLLLGMHISVENIFMLAAIPAGLAALLILQVRSPA 434 >PA2472 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 230 bits (587), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 174/434 (40%), Positives = 244/434 (56%), Gaps = 8/434 (1%) Query: 11 TVHVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVF 70 + V ++ AFQ +L LC L + +DGFD A+G++APA+ DW +S A L P+ Sbjct: 9 KIDVQAFIDAQAVSAFQLRVLSLCFLIVAMDGFDTAAIGFIAPALAHDWQLSPAQLSPIL 68 Query: 71 GAGLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGFG 130 GA L G+ LG+ P+ DR+GR+ VL+LS LFF LA+ +++ L +LRF TG G Sbjct: 69 GAALAGLALGAFAAGPLADRFGRKSVLLLSVLFFGGWSLASAYAGSVETLALLRFFTGLG 128 Query: 131 LGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVGG 190 LG MPNA+ L E+ P R + + CGFT+G+A GG ++A ++PA GW +V +GG Sbjct: 129 LGGAMPNAITLTSEYCPRRHRALMVTAMFCGFTLGSALGGLLAARMVPALGWESVLLLGG 188 Query: 191 AVPLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDD----KTEVVVKETK 246 +PL + LPES++FL R P AR R L+ + D + E+ E+ Sbjct: 189 GLPLASLPLLWACLPESVRFLA-RRAP--DAARLRRILERLGRLPDGWAGRLELPADESD 245 Query: 247 AEGMPVAALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSL 306 P+ + G T+LLW FM L+ +Y L+NWLPTLI G+S A I Sbjct: 246 GTS-PLRQILGAELRGGTLLLWATFFMGLLIIYLLTNWLPTLIGGTGFSLGEAATISAMF 304 Query: 307 QVGGVIGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIV 366 Q+GG +G L LG + RF RVL ++ L I I L ALL + V GFCI Sbjct: 305 QLGGTLGALLLGSAMDRFDAHRVLSLAYVGGALFILGIASLYHSFALLALCVAGVGFCIS 364 Query: 367 GGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAV 426 G Q NALA FYPT R+TG+ WALG+GRIGS+VG + GG L+ L + + + Sbjct: 365 GSQVGANALAADFYPTRSRATGVSWALGLGRIGSIVGSLSGGALLGLGLGFSGILALLVI 424 Query: 427 PALISALTIARLHR 440 PAL++A+ + RL R Sbjct: 425 PALLAAVAVHRLGR 438 >PA4900 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 446 Score = 225 bits (574), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 150/423 (35%), Positives = 228/423 (53%), Gaps = 4/423 (0%) Query: 17 VVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGAGLFG 76 V++ RF + +L ++ DG+D+ G V P ++ +W +S G + LFG Sbjct: 9 VIDAARFNRTHWLILGWGCFIMLFDGYDMVIYGSVVPRLMQEWQLSPVQAGTLGSCALFG 68 Query: 77 MLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGFGLGSIMP 136 ML G +L P+ DR+GRR ++I +TL +L T +L RF TG LG+++P Sbjct: 69 MLFGGTLLAPLADRFGRRRLVIATTLLASLAAFLTGHARDPLELGAGRFFTGLALGALVP 128 Query: 137 NAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVGGAVPLVL 196 +A+ L+ EF+P+ R T + ++S ++VGA ++ A+IPA+GW +VF+V +P++ Sbjct: 129 SAINLISEFAPAGRRSTLVTVMSAFYSVGAVLSALLAIAMIPAWGWQSVFYVA-VLPVLA 187 Query: 197 GLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVVKETKAEGMPVAALF 256 ML WLPES FL L R R ++ LRK+DP+ + V G VA LF Sbjct: 188 VPLMLRWLPESAAFLELKGR-RAELDALLRKVDPDYRPGAERANAVAAEAPSGR-VAQLF 245 Query: 257 RDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSLQVGGVIGTLS 316 +A T+LLW+ M ++ Y L+ WLP L+ GY+ ++ +L VG +G L Sbjct: 246 EGRQAVGTLLLWVAFAMCMLMSYGLNTWLPKLMAGGGYALGSSLAFLVTLNVGATLGALF 305 Query: 317 LGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIVGGQPAVNALA 376 G R G R L F + L P LL ++VAG +G ++A A Sbjct: 306 GGWLADRLGAGRTL-VLFFALAAASLAALGLGPGPWLLNGLLVVAGATTIGTLAVIHAYA 364 Query: 377 GTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAVPALISALTIA 436 FYP +RSTG+GWA G+GR+G++ GP++GG L+AL+ FLA A P +I AL IA Sbjct: 365 AQFYPAWVRSTGVGWAAGVGRLGAIAGPMLGGSLLALELPFQQNFLAFAAPGVIGALAIA 424 Query: 437 RLH 439 +H Sbjct: 425 CIH 427 >Cgl2334 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 446 Score = 187 bits (474), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 126/418 (30%), Positives = 218/418 (52%), Gaps = 4/418 (0%) Query: 12 VHVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFG 71 + + Q + +Q+ ++ + L +DGFDV AM + A A+ ++G+S + LG + Sbjct: 1 MDIRQTINDTAMSRYQWFIVFIAVLLNALDGFDVLAMSFTANAVTEEFGLSGSQLGVLLS 60 Query: 72 AGLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGFGL 131 + LFGM GSL+ P+GDR+GR+ L+++ LF + ++ + + QL V R ITG G+ Sbjct: 61 SALFGMTAGSLLFGPIGDRFGRKNALMIALLFNVVGLVLSATAQSAGQLGVWRLITGIGI 120 Query: 132 GSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVGGA 191 G I+ ++ EFS + +R M + + G+ +GA+ GGF +A LIP +GW +VF G Sbjct: 121 GGILACITVVISEFSNNKNRGMAMSIYAAGYGIGASLGGFGAAQLIPTFGWRSVFAAGAI 180 Query: 192 VPLVLGLAMLVWLPESIQFLVLHRRP---RTQVARWLRKLDPNIVIDDKTEVVVKETKAE 248 + +A +LPES+ +L RRP R ++ R+L + E + KA Sbjct: 181 ATGIATIATFFFLPESVDWLS-TRRPAGARDKINYIARRLGKVGTFELPGEQSLSTKKAG 239 Query: 249 GMPVAALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSLQV 308 A L G ++ LW+ + + YF + W P L+ + G S ++ G L + Sbjct: 240 LQSYAVLVNKENRGTSIKLWVAFGIVMFGFYFANTWTPKLLVETGMSEQQGIIGGLMLSM 299 Query: 309 GGVIGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIVGG 368 GG G+L G +F L + +L+ L++ L +VP++ F + +V G I G Sbjct: 300 GGAFGSLLYGFLTTKFSSRNTLMTFMVLSGLTLILFISSTSVPSIAFASGVVVGMLINGC 359 Query: 369 QPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAV 426 + L+ Y +R+TG+G A+G+GR+G++ P++ G L+ W+ L++ AV Sbjct: 360 VAGLYTLSPQLYSAEVRTTGVGAAIGMGRVGAISAPLLVGGLLDSGWSPTQLYVGVAV 417