BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0401.p (409 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2214 [GEPR] COG0477 Permeases of the major facilitator superfa... 297 3e-80 Cj0484 [GEPR] COG0477 Permeases of the major facilitator superfa... 296 9e-80 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 284 2e-76 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 284 2e-76 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 278 1e-74 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 275 1e-73 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 270 3e-72 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 259 6e-69 STM2290 [GEPR] COG0477 Permeases of the major facilitator superf... 250 5e-66 YPO1563 [GEPR] COG0477 Permeases of the major facilitator superf... 249 1e-65 >PA2214 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 440 Score = 297 bits (761), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 172/396 (43%), Positives = 233/396 (58%), Gaps = 13/396 (3%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 IDR N+G+ R+ L D G+G AA+ GA +FF+GYA FEVPSNL+L R GA+ WL RIM Sbjct: 35 IDRANVGYARAFLQADTGLGDAAFAFGASIFFIGYACFEVPSNLMLHRLGARVWLCRIMV 94 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 TWGL + AM F + TFYVLRFLLG AEAGFFPG+I Y T W P R +A+ +F G Sbjct: 95 TWGLVSAAMMFADDAMTFYVLRFLLGVAEAGFFPGIILYLTYWFPQRSRAQALGLFYFGL 154 Query: 130 ALASILSGPISGGLLQIDG-GGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLTA 188 LA +L GP+SG LL+ G GL WQW+F+ EG+ + L+ +F+L P DA WL+ Sbjct: 155 PLALVLGGPLSGWLLEFHGIFGLANWQWLFVTEGLLASLVGIAAYFYLVDRPRDAGWLSD 214 Query: 189 QERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPSI 248 +++ A+ + +E + P LR Q+L FC +YF+I +++YG F+LP+ Sbjct: 215 EQKRALEGELAEEDTRKQARGPHGF--LSALRSGQVLKFCLVYFTIQMSVYGVVFYLPT- 271 Query: 249 IRKMGSFSDFQ----VGLFNSIPWLISIVAMYAFAALAARF-KHQQAWAATALVIAAAGM 303 ++ SF D Q VGL +IPW+ ++V A R +H+Q A + AA Sbjct: 272 --RIASFLDGQVGLNVGLITAIPWVCALVVTRLVTRQADRSGQHRQLAVAMLGMAAAGIA 329 Query: 304 FASTFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVA 363 ++ GN A ++ CFAA GF + LFW LP YL AA IALINS+GNLGGFVA Sbjct: 330 ASALAGNLGLAVIAFCFAASGFVSVQPLFWTLPTGYLSGAAAASGIALINSLGNLGGFVA 389 Query: 364 PTAFGFLEQRTGSIQGGLMGLAITSLVAAGVVFLAR 399 P +E + + G+ LA L+ G LAR Sbjct: 390 PNLKTLMESQFADPRAGMFALAAVGLL--GACLLAR 423 >Cj0484 [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 410 Score = 296 bits (757), Expect = 9e-80, Method: Compositional matrix adjust. Identities = 169/386 (43%), Positives = 234/386 (60%), Gaps = 9/386 (2%) Query: 8 TSIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 67 + +DR NI FV+SH+ D GIG AAY LGAG+FF+GYA+FEVPSNL L + GAK WL+RI Sbjct: 31 SMLDRTNISFVKSHIEIDAGIGEAAYALGAGIFFIGYAIFEVPSNLFLHKLGAKIWLSRI 90 Query: 68 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 127 M TWGL AM F+ E +FYVLRFLLG EAGF PG+I Y + + PA R +A I+ Sbjct: 91 MITWGLVTMAMIFIQGEISFYVLRFLLGLTEAGFSPGIILYLSYFFPAIYRSKAYGIYQM 150 Query: 128 GSALASILSGPISGGLLQIDGG-GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWL 186 G +A + ISG +L WQWMF+IEG +VL+ F F+LDS P DAKWL Sbjct: 151 GVPIAFVFGSLISGFILDYTPNIYFKNWQWMFLIEGGITVLVGIFCLFYLDSHPKDAKWL 210 Query: 187 TAQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLP 246 +E+ I+ + E + S + + + + F F+YF I L++YG F+LP Sbjct: 211 DIKEKD-----ILLKHIEISNTKAKDYSIKDIFKSILVWKFVFVYFCIQLSVYGVLFYLP 265 Query: 247 SIIRKMGSFS-DFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFA 305 S I ++ + F+VGL N+IPW+ +A+ F +LA + A L++A+ M A Sbjct: 266 SKIAQILQINVGFEVGLLNAIPWIFVFIALPIFTSLADKKHSWNLHAILFLLLASLSMIA 325 Query: 306 STFGNSVYAFV-SICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAP 364 STF ++ AF+ I AA+GF +FW LP L + AA IALI S+GNLGGFVAP Sbjct: 326 STFVTNLAAFLFFISLAAIGFIVIQPIFWNLPTQVLKGKGAAAAIALIGSLGNLGGFVAP 385 Query: 365 TAFGFLEQRTGSIQGGLMGLAITSLV 390 T ++E G ++ GL+ LA+ +++ Sbjct: 386 TLKTYIENHFG-VEFGLIVLALIAIL 410 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 284 bits (727), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 162/387 (41%), Positives = 234/387 (60%), Gaps = 9/387 (2%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 +DRVN+GF + + D+ YGLGAG+FF+GY LFEVPSN++L R GA+ W+ RIM Sbjct: 48 LDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARIMI 107 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 +WGL + AM FV + FYV+RFLLG AEAGFFPG+I Y T W PA RGR F++ Sbjct: 108 SWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMTAV 167 Query: 130 ALASILSGPISGGLLQIDGG--GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLT 187 AL+ ++ GPISG L+ GG GL GWQWMF+IEG+ SV++ V +LD+ + A+WLT Sbjct: 168 ALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLT 227 Query: 188 AQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPS 247 +E++ +T I E+A++ A + + P++ + IYFS + +YG +FWLP+ Sbjct: 228 DEEKALLTRNIAAEEAQKEDAPIAAI-----MASPRVWLMSLIYFSFVMGLYGVSFWLPT 282 Query: 248 IIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFAST 307 +I++ G VGL +IP+ ++VAM A A R + ++ A + A G+ S Sbjct: 283 LIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRERRWHIAIPALAGAIGLVLSA 342 Query: 308 --FGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPT 365 N+ A ++ +G LFW LP A+L AA IALINS+GNL GF++P Sbjct: 343 VWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPY 402 Query: 366 AFGFLEQRTGSIQGGLMGLAITSLVAA 392 A G+L+ T S G+ LA + ++ A Sbjct: 403 AVGWLKDTTRSTDSGMYLLAASMVLGA 429 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 284 bits (727), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 160/375 (42%), Positives = 222/375 (59%), Gaps = 11/375 (2%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 +DR+NIGF + + D+ + AAYGLGAG+FF GY LFEVPSNLLL + GA+ L+RI+ Sbjct: 40 LDRINIGFAKLQMQNDLALSDAAYGLGAGIFFFGYMLFEVPSNLLLVKIGARRTLSRILI 99 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 WG+ + +M FV TFY LRFLLG EAGF PG+IYY TQW P RAMA+ L + Sbjct: 100 LWGIVSASMLFVTDVWTFYALRFLLGVFEAGFAPGMIYYLTQWYPGERMARAMAVVLGAA 159 Query: 130 ALASILSGPISGGLLQ--IDGGGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLT 187 L ++ GP S ++ GGL GWQWMF+ EG+ S+LL + +L PADA+WLT Sbjct: 160 PLGGVIGGPASTWIMGHFAGAGGLAGWQWMFLAEGIPSILLGIAAYGYLVDKPADARWLT 219 Query: 188 AQERSAITSAIVDEQAERMKHQPAQVSP-RQLLRDPQILIFCFIYFSISLTIYGATFWLP 246 +++ I I + P Q S + L +P++ + YF + +Y FWLP Sbjct: 220 DAQKAVIAGDIA-------RAAPGQASSFGKALTEPKLYVLAAAYFCLICGVYAVGFWLP 272 Query: 247 SIIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFAS 306 SI++ G FQ+GL+++IP L IVAMYA + R + +A V+ A + + Sbjct: 273 SILKSAGLSDLFQIGLYSAIPNLAMIVAMYALGRRSDRRGERHLHSAITAVLGAGLLAWA 332 Query: 307 TFGNSV-YAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPT 365 + S A +SI A+ A+ S+FW +PQ +L AAG IALINSIG GGF +PT Sbjct: 333 AYATSFPAALISITLASAAIFASYSVFWAIPQQHLKGTAAAGGIALINSIGLFGGFFSPT 392 Query: 366 AFGFLEQRTGSIQGG 380 G+ ++ TGS+Q G Sbjct: 393 LIGWTKEATGSLQAG 407 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 278 bits (712), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 156/390 (40%), Positives = 235/390 (60%), Gaps = 7/390 (1%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 +DRVN+GF + ++ ++G A YGLGAGLFF+GY FE+PSN+LL + GA+ W+ RIM Sbjct: 57 LDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFIGYFFFEIPSNILLHKLGARLWIARIMI 116 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 TWGL + AFV +E FY+LRFLLGAAEAGF+PGVI Y T W P+ RG A+F +GS Sbjct: 117 TWGLLSALFAFVQTEWQFYILRFLLGAAEAGFYPGVILYLTYWFPSHRRGNMFALFQAGS 176 Query: 130 ALASILSGPISGGLLQ--IDGGGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLT 187 A I P+SG ++ D G GWQWMF++E + +V+L + +LD+ AKWLT Sbjct: 177 PAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAIPAVVLGVVILLYLDNSVKAAKWLT 236 Query: 188 AQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPS 247 +E++ I+ D +A+ K + A S L+++P + + IYF + +G T W+P+ Sbjct: 237 EEEKAIISR---DIEADS-KGKAASHSLMSLVKNPMLWVMMLIYFCFVMGQHGLTLWMPT 292 Query: 248 IIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAG-MFAS 306 +IR G S+ +GL +IP++ +I+AM F+ A ++ ++ ++ A G + A+ Sbjct: 293 LIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYRERRWHLVVPALLGAVGFVVAA 352 Query: 307 TFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPTA 366 + N+ + + + AA G A + LFW LP A L AA IALINS+ NL GF++P Sbjct: 353 SATNTTVSIIFLSMAAAGVLACAPLFWSLPTAILSGAAAAAGIALINSVANLAGFISPYM 412 Query: 367 FGFLEQRTGSIQGGLMGLAITSLVAAGVVF 396 G + T S + G+ LA ++ A +V Sbjct: 413 VGIIRDATHSSELGMYVLAGFLILGAAIVL 442 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 275 bits (703), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 157/392 (40%), Positives = 221/392 (56%), Gaps = 9/392 (2%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 +DRVN+GF + +A D+ YGLGAG+FF+GY E+PSNL+L R GA+ W+ RIM Sbjct: 42 LDRVNVGFAKLQMADDLQFSDTVYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMI 101 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 TWG+ + MAFV + +FYV+RFLLG AEAGFFPG+I Y + W P+ RGR +F+ Sbjct: 102 TWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISV 161 Query: 130 ALASILSGPISGGLLQIDGG--GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLT 187 L+ I+ P+SG ++Q G G GWQWMFI+EG+ SVL+ + + L A WLT Sbjct: 162 PLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLT 221 Query: 188 AQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPS 247 +E+ + + I +E A A R P++ + IYF + Y FWLP+ Sbjct: 222 DKEKDILQTNIENEAAHY-----AHSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPT 276 Query: 248 IIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFAST 307 +IR G +G +IP + V M + A R + ++ A V+ A G+ ST Sbjct: 277 LIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILST 336 Query: 308 F--GNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPT 365 + N V A V + A+G + LFW LP A+L AA IA INS GNLGGFVAP Sbjct: 337 YFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPY 396 Query: 366 AFGFLEQRTGSIQGGLMGLAITSLVAAGVVFL 397 G+L+ T S G++ ++ T + A +VFL Sbjct: 397 MMGYLKDLTQSTTTGMLIISTTLFIGAALVFL 428 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 270 bits (691), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 158/392 (40%), Positives = 227/392 (57%), Gaps = 10/392 (2%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 IDR N+ + + + + +G+ AAYGLGA LFF+GY LFE P+NL+L R GA+ W RIM Sbjct: 33 IDRQNVSYAKLDMVSALGLSEAAYGLGASLFFIGYFLFEAPANLILARVGARVWFARIMF 92 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 +WGL A+ F + FYVLRFLLG AEAGFFPGV+Y T W P + R R + +F+ S Sbjct: 93 SWGLVTLALGFTQNAAMFYVLRFLLGVAEAGFFPGVLYVLTLWYPQAHRARMVGLFMIAS 152 Query: 130 ALASILSGPISGGLLQIDG-GGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLTA 188 A A+ + I G LL +DG GL GWQW+F++ G +VLL +V + L S P+DA+WL Sbjct: 153 AFANAVGAAIGGLLLGMDGFLGLAGWQWVFLVTGAPAVLLAPYVLWRLPSGPSDARWLPD 212 Query: 189 QERSAITSAIVDEQ-AERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPS 247 E+S + S + E+ E H+ A + + DP++L+ +Y + L+ YG ++WLP+ Sbjct: 213 VEKSWLASTLAAERGGEVDDHRGAW----KAIFDPRVLMLAGLYIGMPLSAYGLSYWLPT 268 Query: 248 IIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAW--AATALVIAAAGMFA 305 I++ G S+ G N IPWL+ VA++ AAR AW A L+ A A + Sbjct: 269 IVKSFG-VSNTVNGFINVIPWLLVAVALWFVPRHAAR-HGASAWHIAGPVLLAAVALSLS 326 Query: 306 STFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPT 365 + F +C AA AA +FW LP ++L AA IA IN++GNLGGF+A Sbjct: 327 VILPGAALKFTMLCIAAPAIFAAQPVFWSLPPSFLSGPRAAAGIATINAVGNLGGFIAQN 386 Query: 366 AFGFLEQRTGSIQGGLMGLAITSLVAAGVVFL 397 + TGS ++ LA LV + ++F+ Sbjct: 387 LVPVVRDATGSELAPMLALAAVLLVTSLLIFI 418 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 259 bits (663), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 148/396 (37%), Positives = 220/396 (55%), Gaps = 6/396 (1%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 IDR N+ + + + + + AYGLGA LFF+GY LFEVPSNL L RFGA W RI+ Sbjct: 90 IDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIGYFLFEVPSNLFLNRFGASKWFARILV 149 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 +WG A+A+ + T FY+LRFLLG EAGFFPGV++ T W P RGR + +F+ S Sbjct: 150 SWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPGVLFLMTLWFPRDYRGRMIGLFMIFS 209 Query: 130 ALASILSGPISGGLLQIDGG-GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLTA 188 ALA+ + P+ G LL +DG G GW+W+F+ G+ +V+ +F+LD P AK+LT Sbjct: 210 ALANAVGAPLGGMLLDLDGFLGYAGWEWVFLATGIPAVIAGIVTFFYLDDTPDKAKFLTQ 269 Query: 189 QERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPSI 248 E+ + + + +E +H + L +P++L Y L YG ++WLP+I Sbjct: 270 DEKDWLKNRLAEENKGMEEHAEDGF---KALVNPRVLFMALCYVGFPLAAYGLSYWLPTI 326 Query: 249 IRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAW-AATALVIAAAGMFAST 307 ++ G S+ G N IPW+I +A++ + A + K++ + A V A + ++ Sbjct: 327 VKSFGV-SNTTNGFINIIPWIIVAIALFVVPSAADKAKNKTPYIVGPAFVGAFCLLMSAL 385 Query: 308 FGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPTAF 367 + V F +C AA G A +FW LP +L AA IA INS+GNLGGFVA Sbjct: 386 LSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAGAAAGIAAINSVGNLGGFVAQNVV 445 Query: 368 GFLEQRTGSIQGGLMGLAITSLVAAGVVFLARSGPG 403 +++ +TGS + LA +A +V +A G Sbjct: 446 PWIKDQTGSTIAPMFFLAFCLALAGVLVIIATRKMG 481 >STM2290 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 429 Score = 250 bits (638), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 138/389 (35%), Positives = 218/389 (56%), Gaps = 7/389 (1%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 +DR NIGF + D G+ AY LGAG+FFV YA VP+NLL+++FGA+ W+ Sbjct: 30 LDRSNIGFAKETYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKFGARTWIGTTTL 89 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 WG + AMA+ +SE F ++R LLGAAEAGFFPG+IY +QW P R M +F G+ Sbjct: 90 LWGFLSAAMAWADSEAKFLIIRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGA 149 Query: 130 ALASILSGPISGGLLQIDG-GGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLTA 188 LA L P+SG LL++ G G GW WMF+IEG+ ++ F +FWLD P A++L+ Sbjct: 150 PLALTLGSPLSGALLEMHGFMGHPGWFWMFVIEGLLAIGAGIFTFFWLDDTPQQARFLSL 209 Query: 189 QERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPSI 248 +E++A+ + E+ +++ + A LR+ ++ IY +I + +YG F+LP+ Sbjct: 210 EEKNALIRQLASEEEKKVTSRLADA-----LRNGRVWQLAIIYLTIQVAVYGLIFFLPTQ 264 Query: 249 IRK-MGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFAST 307 + +G+ F + ++PW+ +++ + + R ++ AA L+ A G+ S Sbjct: 265 VAALLGTKVGFTASVVTAVPWVAALLGTWLIPRYSDRTGDRRNVAAVTLLAAGIGIGLSG 324 Query: 308 FGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPTAF 367 + V A +++C AAVGF A +FW +P L A I +N G +GGF+AP Sbjct: 325 LVSPVLAILALCVAAVGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILR 384 Query: 368 GFLEQRTGSIQGGLMGLAITSLVAAGVVF 396 E S GL+ LA +++ + ++F Sbjct: 385 VKAETLFASDAAGLLTLAGVAIIGSLIIF 413 >YPO1563 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 466 Score = 249 bits (635), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 141/390 (36%), Positives = 219/390 (56%), Gaps = 8/390 (2%) Query: 10 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 69 IDR+N+GF + ++ D+G+ +A+ LGAG+FF YALF +P+NL++ + GAK WL+ Sbjct: 68 IDRINVGFAKDAMSADIGLSQSAFALGAGIFFAAYALFGIPANLMMNKLGAKVWLSSTTV 127 Query: 70 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 129 WGL + V++E F +LRFLLG AEAGF+PG++ + + P R + IF+ G Sbjct: 128 VWGLLSAGTGLVSNEYQFVILRFLLGVAEAGFYPGILLLASIYFPNKIRASVIGIFVLGV 187 Query: 130 ALASILSGPISGGLLQIDGG-GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLTA 188 A L PISG LL + G G GW WMF++EG+ +V L F +F+LD PA A++L Sbjct: 188 PAALTLGSPISGALLDMQGFLGQPGWFWMFLLEGLPAVGLGIFAFFYLDDSPATARYLNP 247 Query: 189 QERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPSI 248 +E+ A+ + + EQ++ S + +L P++ IY +I + +YG F+LPS Sbjct: 248 EEKQALLTQLSIEQSDTESS-----SVKAVLLSPKVWHLALIYGTIQVGVYGLIFFLPSQ 302 Query: 249 IRK-MGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAAT-ALVIAAAGMFAS 306 + +GS F+ L +IPW S + +Y A R H++ AT LV+AA G+ S Sbjct: 303 VATLLGSTLGFKESLVAAIPWAFSALGVYYIPRYADRKTHRRNPIATLNLVVAAIGLIIS 362 Query: 307 TFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPTA 366 + + V A ++C A+GF A +FW P L + A I ++G F+AP Sbjct: 363 AYASPVLAIAALCLCAIGFLAVQPIFWTFPAQILSGKALAAGIGFCTTMGAFFSFLAPII 422 Query: 367 FGFLEQRTGSIQGGLMGLAITSLVAAGVVF 396 E + S GL+ LA+ SL++A ++F Sbjct: 423 RVEAESQFNSPPAGLITLALFSLLSATLIF 452