BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0400.p (411 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2214 [GEPR] COG0477 Permeases of the major facilitator superfa... 300 5e-81 Cj0484 [GEPR] COG0477 Permeases of the major facilitator superfa... 295 1e-79 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 288 1e-77 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 288 1e-77 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 283 5e-76 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 278 2e-74 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 274 2e-73 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 263 5e-70 STM2290 [GEPR] COG0477 Permeases of the major facilitator superf... 252 1e-66 YPO1563 [GEPR] COG0477 Permeases of the major facilitator superf... 251 2e-66 >PA2214 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 440 Score = 300 bits (767), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 173/398 (43%), Positives = 235/398 (59%), Gaps = 13/398 (3%) Query: 10 AYIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 69 A+IDR N+G+ R+ L D G+G AA+ GA +FF+GYA FEVPSNL+L R GA+ WL RI Sbjct: 33 AFIDRANVGYARAFLQADTGLGDAAFAFGASIFFIGYACFEVPSNLMLHRLGARVWLCRI 92 Query: 70 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 129 M TWGL + AM F + TFYVLRFLLG AEAGFFPG+I Y T W P R +A+ +F Sbjct: 93 MVTWGLVSAAMMFADDAMTFYVLRFLLGVAEAGFFPGIILYLTYWFPQRSRAQALGLFYF 152 Query: 130 GSALASILSGPISGGLLQIDG-GGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWL 188 G LA +L GP+SG LL+ G GL WQW+F+ EG+ + L+ +F+L P DA WL Sbjct: 153 GLPLALVLGGPLSGWLLEFHGIFGLANWQWLFVTEGLLASLVGIAAYFYLVDRPRDAGWL 212 Query: 189 TAQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLP 248 + +++ A+ + +E + P LR Q+L FC +YF+I +++YG F+LP Sbjct: 213 SDEQKRALEGELAEEDTRKQARGPHGF--LSALRSGQVLKFCLVYFTIQMSVYGVVFYLP 270 Query: 249 SIIRKMGSFSDFQ----VGLFNSIPWLISIVAMYAFAALAARF-KHQQAWAATALVIAAA 303 + ++ SF D Q VGL +IPW+ ++V A R +H+Q A + AA Sbjct: 271 T---RIASFLDGQVGLNVGLITAIPWVCALVVTRLVTRQADRSGQHRQLAVAMLGMAAAG 327 Query: 304 GMFASTFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGF 363 ++ GN A ++ CFAA GF + LFW LP YL AA IALINS+GNLGGF Sbjct: 328 IAASALAGNLGLAVIAFCFAASGFVSVQPLFWTLPTGYLSGAAAASGIALINSLGNLGGF 387 Query: 364 VAPTAFGFLEQRTGSIQGGLMGLAITSLVAAGVVFLAR 401 VAP +E + + G+ LA L+ G LAR Sbjct: 388 VAPNLKTLMESQFADPRAGMFALAAVGLL--GACLLAR 423 >Cj0484 [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 410 Score = 295 bits (755), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 169/384 (44%), Positives = 233/384 (60%), Gaps = 9/384 (2%) Query: 12 IDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIMA 71 +DR NI FV+SH+ D GIG AAY LGAG+FF+GYA+FEVPSNL L + GAK WL+RIM Sbjct: 33 LDRTNISFVKSHIEIDAGIGEAAYALGAGIFFIGYAIFEVPSNLFLHKLGAKIWLSRIMI 92 Query: 72 TWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSGS 131 TWGL AM F+ E +FYVLRFLLG EAGF PG+I Y + + PA R +A I+ G Sbjct: 93 TWGLVTMAMIFIQGEISFYVLRFLLGLTEAGFSPGIILYLSYFFPAIYRSKAYGIYQMGV 152 Query: 132 ALASILSGPISGGLLQIDGG-GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWLTA 190 +A + ISG +L WQWMF+IEG +VL+ F F+LDS P DAKWL Sbjct: 153 PIAFVFGSLISGFILDYTPNIYFKNWQWMFLIEGGITVLVGIFCLFYLDSHPKDAKWLDI 212 Query: 191 QERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLPSI 250 +E+ I+ + E + S + + + + F F+YF I L++YG F+LPS Sbjct: 213 KEKD-----ILLKHIEISNTKAKDYSIKDIFKSILVWKFVFVYFCIQLSVYGVLFYLPSK 267 Query: 251 IRKMGSFS-DFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFAST 309 I ++ + F+VGL N+IPW+ +A+ F +LA + A L++A+ M AST Sbjct: 268 IAQILQINVGFEVGLLNAIPWIFVFIALPIFTSLADKKHSWNLHAILFLLLASLSMIAST 327 Query: 310 FGNSVYAFV-SICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPTA 368 F ++ AF+ I AA+GF +FW LP L + AA IALI S+GNLGGFVAPT Sbjct: 328 FVTNLAAFLFFISLAAIGFIVIQPIFWNLPTQVLKGKGAAAAIALIGSLGNLGGFVAPTL 387 Query: 369 FGFLEQRTGSIQGGLMGLAITSLV 392 ++E G ++ GL+ LA+ +++ Sbjct: 388 KTYIENHFG-VEFGLIVLALIAIL 410 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 288 bits (738), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 164/389 (42%), Positives = 236/389 (60%), Gaps = 9/389 (2%) Query: 10 AYIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 69 AY+DRVN+GF + + D+ YGLGAG+FF+GY LFEVPSN++L R GA+ W+ RI Sbjct: 46 AYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARI 105 Query: 70 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 129 M +WGL + AM FV + FYV+RFLLG AEAGFFPG+I Y T W PA RGR F++ Sbjct: 106 MISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMT 165 Query: 130 GSALASILSGPISGGLLQIDGG--GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKW 187 AL+ ++ GPISG L+ GG GL GWQWMF+IEG+ SV++ V +LD+ + A+W Sbjct: 166 AVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARW 225 Query: 188 LTAQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWL 247 LT +E++ +T I E+A++ A + + P++ + IYFS + +YG +FWL Sbjct: 226 LTDEEKALLTRNIAAEEAQKEDAPIAAI-----MASPRVWLMSLIYFSFVMGLYGVSFWL 280 Query: 248 PSIIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFA 307 P++I++ G VGL +IP+ ++VAM A A R + ++ A + A G+ Sbjct: 281 PTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRERRWHIAIPALAGAIGLVL 340 Query: 308 ST--FGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVA 365 S N+ A ++ +G LFW LP A+L AA IALINS+GNL GF++ Sbjct: 341 SAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLS 400 Query: 366 PTAFGFLEQRTGSIQGGLMGLAITSLVAA 394 P A G+L+ T S G+ LA + ++ A Sbjct: 401 PYAVGWLKDTTRSTDSGMYLLAASMVLGA 429 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 288 bits (738), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 162/377 (42%), Positives = 224/377 (59%), Gaps = 11/377 (2%) Query: 10 AYIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 69 AY+DR+NIGF + + D+ + AAYGLGAG+FF GY LFEVPSNLLL + GA+ L+RI Sbjct: 38 AYLDRINIGFAKLQMQNDLALSDAAYGLGAGIFFFGYMLFEVPSNLLLVKIGARRTLSRI 97 Query: 70 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 129 + WG+ + +M FV TFY LRFLLG EAGF PG+IYY TQW P RAMA+ L Sbjct: 98 LILWGIVSASMLFVTDVWTFYALRFLLGVFEAGFAPGMIYYLTQWYPGERMARAMAVVLG 157 Query: 130 GSALASILSGPISGGLLQ--IDGGGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKW 187 + L ++ GP S ++ GGL GWQWMF+ EG+ S+LL + +L PADA+W Sbjct: 158 AAPLGGVIGGPASTWIMGHFAGAGGLAGWQWMFLAEGIPSILLGIAAYGYLVDKPADARW 217 Query: 188 LTAQERSAITSAIVDEQAERMKHQPAQVSP-RQLLRDPQILIFCFIYFSISLTIYGATFW 246 LT +++ I I + P Q S + L +P++ + YF + +Y FW Sbjct: 218 LTDAQKAVIAGDIA-------RAAPGQASSFGKALTEPKLYVLAAAYFCLICGVYAVGFW 270 Query: 247 LPSIIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMF 306 LPSI++ G FQ+GL+++IP L IVAMYA + R + +A V+ A + Sbjct: 271 LPSILKSAGLSDLFQIGLYSAIPNLAMIVAMYALGRRSDRRGERHLHSAITAVLGAGLLA 330 Query: 307 ASTFGNSV-YAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVA 365 + + S A +SI A+ A+ S+FW +PQ +L AAG IALINSIG GGF + Sbjct: 331 WAAYATSFPAALISITLASAAIFASYSVFWAIPQQHLKGTAAAGGIALINSIGLFGGFFS 390 Query: 366 PTAFGFLEQRTGSIQGG 382 PT G+ ++ TGS+Q G Sbjct: 391 PTLIGWTKEATGSLQAG 407 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 283 bits (724), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 158/392 (40%), Positives = 237/392 (60%), Gaps = 7/392 (1%) Query: 10 AYIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 69 AY+DRVN+GF + ++ ++G A YGLGAGLFF+GY FE+PSN+LL + GA+ W+ RI Sbjct: 55 AYLDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFIGYFFFEIPSNILLHKLGARLWIARI 114 Query: 70 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 129 M TWGL + AFV +E FY+LRFLLGAAEAGF+PGVI Y T W P+ RG A+F + Sbjct: 115 MITWGLLSALFAFVQTEWQFYILRFLLGAAEAGFYPGVILYLTYWFPSHRRGNMFALFQA 174 Query: 130 GSALASILSGPISGGLLQ--IDGGGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKW 187 GS A I P+SG ++ D G GWQWMF++E + +V+L + +LD+ AKW Sbjct: 175 GSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAIPAVVLGVVILLYLDNSVKAAKW 234 Query: 188 LTAQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWL 247 LT +E++ I+ D +A+ K + A S L+++P + + IYF + +G T W+ Sbjct: 235 LTEEEKAIISR---DIEADS-KGKAASHSLMSLVKNPMLWVMMLIYFCFVMGQHGLTLWM 290 Query: 248 PSIIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAG-MF 306 P++IR G S+ +GL +IP++ +I+AM F+ A ++ ++ ++ A G + Sbjct: 291 PTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYRERRWHLVVPALLGAVGFVV 350 Query: 307 ASTFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAP 366 A++ N+ + + + AA G A + LFW LP A L AA IALINS+ NL GF++P Sbjct: 351 AASATNTTVSIIFLSMAAAGVLACAPLFWSLPTAILSGAAAAAGIALINSVANLAGFISP 410 Query: 367 TAFGFLEQRTGSIQGGLMGLAITSLVAAGVVF 398 G + T S + G+ LA ++ A +V Sbjct: 411 YMVGIIRDATHSSELGMYVLAGFLILGAAIVL 442 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 278 bits (711), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 158/393 (40%), Positives = 222/393 (56%), Gaps = 9/393 (2%) Query: 11 YIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRIM 70 Y+DRVN+GF + +A D+ YGLGAG+FF+GY E+PSNL+L R GA+ W+ RIM Sbjct: 41 YLDRVNVGFAKLQMADDLQFSDTVYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIM 100 Query: 71 ATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLSG 130 TWG+ + MAFV + +FYV+RFLLG AEAGFFPG+I Y + W P+ RGR +F+ Sbjct: 101 ITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVIS 160 Query: 131 SALASILSGPISGGLLQIDGG--GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWL 188 L+ I+ P+SG ++Q G G GWQWMFI+EG+ SVL+ + + L A WL Sbjct: 161 VPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWL 220 Query: 189 TAQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLP 248 T +E+ + + I +E A A R P++ + IYF + Y FWLP Sbjct: 221 TDKEKDILQTNIENEAAHY-----AHSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLP 275 Query: 249 SIIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFAS 308 ++IR G +G +IP + V M + A R + ++ A V+ A G+ S Sbjct: 276 TLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILS 335 Query: 309 TF--GNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAP 366 T+ N V A V + A+G + LFW LP A+L AA IA INS GNLGGFVAP Sbjct: 336 TYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAP 395 Query: 367 TAFGFLEQRTGSIQGGLMGLAITSLVAAGVVFL 399 G+L+ T S G++ ++ T + A +VFL Sbjct: 396 YMMGYLKDLTQSTTTGMLIISTTLFIGAALVFL 428 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 274 bits (701), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 160/394 (40%), Positives = 229/394 (58%), Gaps = 10/394 (2%) Query: 10 AYIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 69 AYIDR N+ + + + + +G+ AAYGLGA LFF+GY LFE P+NL+L R GA+ W RI Sbjct: 31 AYIDRQNVSYAKLDMVSALGLSEAAYGLGASLFFIGYFLFEAPANLILARVGARVWFARI 90 Query: 70 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 129 M +WGL A+ F + FYVLRFLLG AEAGFFPGV+Y T W P + R R + +F+ Sbjct: 91 MFSWGLVTLALGFTQNAAMFYVLRFLLGVAEAGFFPGVLYVLTLWYPQAHRARMVGLFMI 150 Query: 130 GSALASILSGPISGGLLQIDG-GGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWL 188 SA A+ + I G LL +DG GL GWQW+F++ G +VLL +V + L S P+DA+WL Sbjct: 151 ASAFANAVGAAIGGLLLGMDGFLGLAGWQWVFLVTGAPAVLLAPYVLWRLPSGPSDARWL 210 Query: 189 TAQERSAITSAIVDEQ-AERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWL 247 E+S + S + E+ E H+ A + + DP++L+ +Y + L+ YG ++WL Sbjct: 211 PDVEKSWLASTLAAERGGEVDDHRGAW----KAIFDPRVLMLAGLYIGMPLSAYGLSYWL 266 Query: 248 PSIIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAW--AATALVIAAAGM 305 P+I++ G S+ G N IPWL+ VA++ AAR AW A L+ A A Sbjct: 267 PTIVKSFG-VSNTVNGFINVIPWLLVAVALWFVPRHAAR-HGASAWHIAGPVLLAAVALS 324 Query: 306 FASTFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVA 365 + + F +C AA AA +FW LP ++L AA IA IN++GNLGGF+A Sbjct: 325 LSVILPGAALKFTMLCIAAPAIFAAQPVFWSLPPSFLSGPRAAAGIATINAVGNLGGFIA 384 Query: 366 PTAFGFLEQRTGSIQGGLMGLAITSLVAAGVVFL 399 + TGS ++ LA LV + ++F+ Sbjct: 385 QNLVPVVRDATGSELAPMLALAAVLLVTSLLIFI 418 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 263 bits (673), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 150/398 (37%), Positives = 222/398 (55%), Gaps = 6/398 (1%) Query: 10 AYIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 69 AYIDR N+ + + + + + AYGLGA LFF+GY LFEVPSNL L RFGA W RI Sbjct: 88 AYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIGYFLFEVPSNLFLNRFGASKWFARI 147 Query: 70 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 129 + +WG A+A+ + T FY+LRFLLG EAGFFPGV++ T W P RGR + +F+ Sbjct: 148 LVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPGVLFLMTLWFPRDYRGRMIGLFMI 207 Query: 130 GSALASILSGPISGGLLQIDGG-GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWL 188 SALA+ + P+ G LL +DG G GW+W+F+ G+ +V+ +F+LD P AK+L Sbjct: 208 FSALANAVGAPLGGMLLDLDGFLGYAGWEWVFLATGIPAVIAGIVTFFYLDDTPDKAKFL 267 Query: 189 TAQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLP 248 T E+ + + + +E +H + L +P++L Y L YG ++WLP Sbjct: 268 TQDEKDWLKNRLAEENKGMEEHAEDGF---KALVNPRVLFMALCYVGFPLAAYGLSYWLP 324 Query: 249 SIIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAW-AATALVIAAAGMFA 307 +I++ G S+ G N IPW+I +A++ + A + K++ + A V A + + Sbjct: 325 TIVKSFGV-SNTTNGFINIIPWIIVAIALFVVPSAADKAKNKTPYIVGPAFVGAFCLLMS 383 Query: 308 STFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPT 367 + + V F +C AA G A +FW LP +L AA IA INS+GNLGGFVA Sbjct: 384 ALLSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAGAAAGIAAINSVGNLGGFVAQN 443 Query: 368 AFGFLEQRTGSIQGGLMGLAITSLVAAGVVFLARSGPG 405 +++ +TGS + LA +A +V +A G Sbjct: 444 VVPWIKDQTGSTIAPMFFLAFCLALAGVLVIIATRKMG 481 >STM2290 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 429 Score = 252 bits (643), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 139/391 (35%), Positives = 220/391 (56%), Gaps = 7/391 (1%) Query: 10 AYIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 69 A++DR NIGF + D G+ AY LGAG+FFV YA VP+NLL+++FGA+ W+ Sbjct: 28 AFLDRSNIGFAKETYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKFGARTWIGTT 87 Query: 70 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 129 WG + AMA+ +SE F ++R LLGAAEAGFFPG+IY +QW P R M +F Sbjct: 88 TLLWGFLSAAMAWADSEAKFLIIRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYM 147 Query: 130 GSALASILSGPISGGLLQIDG-GGLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWL 188 G+ LA L P+SG LL++ G G GW WMF+IEG+ ++ F +FWLD P A++L Sbjct: 148 GAPLALTLGSPLSGALLEMHGFMGHPGWFWMFVIEGLLAIGAGIFTFFWLDDTPQQARFL 207 Query: 189 TAQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLP 248 + +E++A+ + E+ +++ + A LR+ ++ IY +I + +YG F+LP Sbjct: 208 SLEEKNALIRQLASEEEKKVTSRLADA-----LRNGRVWQLAIIYLTIQVAVYGLIFFLP 262 Query: 249 SIIRK-MGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAATALVIAAAGMFA 307 + + +G+ F + ++PW+ +++ + + R ++ AA L+ A G+ Sbjct: 263 TQVAALLGTKVGFTASVVTAVPWVAALLGTWLIPRYSDRTGDRRNVAAVTLLAAGIGIGL 322 Query: 308 STFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAPT 367 S + V A +++C AAVGF A +FW +P L A I +N G +GGF+AP Sbjct: 323 SGLVSPVLAILALCVAAVGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPI 382 Query: 368 AFGFLEQRTGSIQGGLMGLAITSLVAAGVVF 398 E S GL+ LA +++ + ++F Sbjct: 383 LRVKAETLFASDAAGLLTLAGVAIIGSLIIF 413 >YPO1563 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 466 Score = 251 bits (641), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 142/392 (36%), Positives = 221/392 (56%), Gaps = 8/392 (2%) Query: 10 AYIDRVNIGFVRSHLATDVGIGTAAYGLGAGLFFVGYALFEVPSNLLLQRFGAKAWLTRI 69 A+IDR+N+GF + ++ D+G+ +A+ LGAG+FF YALF +P+NL++ + GAK WL+ Sbjct: 66 AFIDRINVGFAKDAMSADIGLSQSAFALGAGIFFAAYALFGIPANLMMNKLGAKVWLSST 125 Query: 70 MATWGLAATAMAFVNSETTFYVLRFLLGAAEAGFFPGVIYYFTQWLPASERGRAMAIFLS 129 WGL + V++E F +LRFLLG AEAGF+PG++ + + P R + IF+ Sbjct: 126 TVVWGLLSAGTGLVSNEYQFVILRFLLGVAEAGFYPGILLLASIYFPNKIRASVIGIFVL 185 Query: 130 GSALASILSGPISGGLLQIDGG-GLHGWQWMFIIEGMASVLLCGFVWFWLDSMPADAKWL 188 G A L PISG LL + G G GW WMF++EG+ +V L F +F+LD PA A++L Sbjct: 186 GVPAALTLGSPISGALLDMQGFLGQPGWFWMFLLEGLPAVGLGIFAFFYLDDSPATARYL 245 Query: 189 TAQERSAITSAIVDEQAERMKHQPAQVSPRQLLRDPQILIFCFIYFSISLTIYGATFWLP 248 +E+ A+ + + EQ++ S + +L P++ IY +I + +YG F+LP Sbjct: 246 NPEEKQALLTQLSIEQSDTESS-----SVKAVLLSPKVWHLALIYGTIQVGVYGLIFFLP 300 Query: 249 S-IIRKMGSFSDFQVGLFNSIPWLISIVAMYAFAALAARFKHQQAWAAT-ALVIAAAGMF 306 S + +GS F+ L +IPW S + +Y A R H++ AT LV+AA G+ Sbjct: 301 SQVATLLGSTLGFKESLVAAIPWAFSALGVYYIPRYADRKTHRRNPIATLNLVVAAIGLI 360 Query: 307 ASTFGNSVYAFVSICFAAVGFKAASSLFWPLPQAYLDARIAAGVIALINSIGNLGGFVAP 366 S + + V A ++C A+GF A +FW P L + A I ++G F+AP Sbjct: 361 ISAYASPVLAIAALCLCAIGFLAVQPIFWTFPAQILSGKALAAGIGFCTTMGAFFSFLAP 420 Query: 367 TAFGFLEQRTGSIQGGLMGLAITSLVAAGVVF 398 E + S GL+ LA+ SL++A ++F Sbjct: 421 IIRVEAESQFNSPPAGLITLALFSLLSATLIF 452