BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0288.p (312 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3352 [E] COG2423 Predicted ornithine cyclodeaminase, mu-cryst... 172 1e-42 SPAP11E10.01 [E] COG2423 Predicted ornithine cyclodeaminase, mu-... 87 4e-17 PA4908 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crysta... 83 1e-15 mlr2282 Non COG 79 9e-15 SSO0378 [E] COG2423 Predicted ornithine cyclodeaminase, mu-cryst... 76 1e-13 MA3252 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crysta... 73 8e-13 AF1665 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crysta... 69 2e-11 MTH1495 [E] COG2423 Predicted ornithine cyclodeaminase, mu-cryst... 67 6e-11 VNG2224G [E] COG2423 Predicted ornithine cyclodeaminase, mu-crys... 63 8e-10 MK1411 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crysta... 61 3e-09 >RSc3352 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Rso Ralstonia solanacearum Length = 334 Score = 172 bits (435), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 124/323 (38%), Positives = 163/323 (50%), Gaps = 20/323 (6%) Query: 1 MHILDPRQTAQALPYAALVDALARATQELADGRIRAPERQVVPIDAASVLLGMPAIADDL 60 + LD TA LPY AL DA+A+ ++ GR +AP R V+P+ LL MPA ++ Sbjct: 2 LQTLDATATAARLPYVALADAIAQVLRDARAGRAQAPARLVMPVPGPGSLLLMPASNAEI 61 Query: 61 SVTKLITVHADNARHQLPAIQGEVIAFETQTGRRLALMDGPTVTARRTAAMSMLGIRTLL 120 ++TK+ITVH NA H LPAI GEV+ + TG R L+DGPTVTA RTAA+S+L R L Sbjct: 62 AITKMITVHPHNAAHGLPAIHGEVVVMDAATGVRRLLLDGPTVTAHRTAAVSLLAARLLA 121 Query: 121 PRQPQSALLIGTGVQSAAHADALVEFFGVRQFWIVARDLARTQAFCR-----ALSERHPQ 175 P LLIG G Q+ AH +A G R+ IV R A +A L Sbjct: 122 PEPAGDLLLIGAGAQARAHLEAFRMGLGTRRVTIVTRTEANAEALAAHARKLGLEATAVA 181 Query: 176 AVASLLPTQMLQQDLPHTDVVIALTTSRSAVIPEHIAADTLAIG-----------VGAFK 224 A + Q + LP+ +VI T S V+P+ + T +G VGAF+ Sbjct: 182 AGDAAGMAQAARIVLPYAPLVITATPSTQPVLPDLAESGTAGVGQVWRAQHFIAAVGAFR 241 Query: 225 PDMVEFPASLLH----ARRIVVDDLAGAHHEAGDLIQAGVDWFGVVAIADVVAGRTPAAT 280 P+M E P L + R+ D L EAGDL+QAGV W V + + Sbjct: 242 PEMAELPPRLCMQAAASDRLFADTLTDLDAEAGDLLQAGVPWSCVRPLQQCIDAAPDIGA 301 Query: 281 LASGAALPVFKTVGQAAWDLAAA 303 A+ VFK+VG A WDLAA Sbjct: 302 QAAPGVPVVFKSVGSALWDLAAC 324 >SPAP11E10.01 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Spo Schizosaccharomyces pombe Length = 330 Score = 87.4 bits (215), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 91/320 (28%), Positives = 142/320 (44%), Gaps = 29/320 (9%) Query: 7 RQT-AQALPYAALVDALARATQELADGRIRAPERQVVPID-------AASVLLGMPA-IA 57 R+T + +L + L++AL +E+ + P R PID A ++LL MP I Sbjct: 10 RETLSSSLGWIPLINAL----REIFTENVVCPTRLHYPIDEDNPSSTANNILLIMPCWIP 65 Query: 58 DDLSVTKLITVHADNARHQLPAIQGEVIAFETQTGRRLALMDGPTVTARRTAAMSMLGIR 117 K + V +N +H LP++ + + TG LA +DG +T+RRTAA S L Sbjct: 66 GKFLGVKQVNVFPENTKHGLPSLSSHYLLSDATTGCHLAQLDGNELTSRRTAAASALASS 125 Query: 118 TLLPRQPQSALLIGTGVQSAAHADALVEFFGVRQFWIVARDLARTQAFCRALSERHPQAV 177 L S L+IG+G + A +R I ++ S+ P Sbjct: 126 YLSKEDSTSLLIIGSGKVAEKLIHAHCSVRPIRSVRIWNHRFESAKSLASRASKELPSIQ 185 Query: 178 ASLLPTQMLQQDLPHTDVVIALTTSRSAVI-PEHIAADTLAIGVGAFKPDMVEFPASLLH 236 +P Q L+ + +D++ + T S+ +I I T VG F P M E + + Sbjct: 186 IDAVPIQNLENAVKCSDIISSATLSKKPIIVGSWINPGTHIDLVGGFTPHMHEADSKCIQ 245 Query: 237 ARRIVVDDLAGAHHEAGDL---IQAGV--------DWFGVVAIADVVAGRTPAATLASGA 285 + VD GA HEAGDL I+ G+ D F + + +GR+ A Sbjct: 246 ISNVFVDTRKGALHEAGDLLTPIKEGLFSPNEVIADLFDLC--NNKHSGRSQLKNPAE-- 301 Query: 286 ALPVFKTVGQAAWDLAAARV 305 A+ +FK+VG + DLAAA + Sbjct: 302 AITLFKSVGDSREDLAAASL 321 >PA4908 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Pae Pseudomonas aeruginosa Length = 310 Score = 82.8 bits (203), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 100/310 (32%), Positives = 136/310 (43%), Gaps = 30/310 (9%) Query: 8 QTAQALPYAALVDALARATQELADGRIRAPERQVVPIDAASVLLGMPAIADDLSV-TKLI 66 + A+ L Y L++AL + AP R + A + LL MP + KL+ Sbjct: 11 EVAERLAYPQLIEALRIGLAKPCS----APLRNCHALPAQASLLQMPVWQAGAGIGVKLV 66 Query: 67 TVHADNARHQLPAIQGEVIAFETQTGRRLALMDGPTVTARRTAAMSMLGIRTLLPRQPQS 126 TV N LPA+ F+ + GR LAL++ +TARRTA S L L + Sbjct: 67 TVFPGNGARGLPAVAAVFALFDGEDGRPLALLEASELTARRTACSSALAADYLARDDARR 126 Query: 127 ALLIGTGVQSAAHADALVEFFGVRQFWIVARDLARTQAFCRALSERHPQAVASLLPTQML 186 L++G G +A A R I RD A+ A L E A A+ L Sbjct: 127 LLVVGCGTLAAHMVRAHACVRDYRHIDIWGRDPAKAAALAARLREEGYPARAA----DGL 182 Query: 187 QQDLPHTDVVIALTTSRSAVIPEHIAADTLAIG-VGAFKPDMVEFPASLLHARRIVVDDL 245 + + D V +TTSR A++ + + VGAF P M E + R+VVD Sbjct: 183 RAAVEAADCVSCVTTSREALVRGAWLKPGVHLDLVGAFLPSMRETDVLAVARARVVVDTR 242 Query: 246 AGAHHEAGDLIQAGVDWFGVVAIADVVAGRTPAAT----LASGAA-------LPVFKTVG 294 AGA EAGDL+Q AIA+ GR +T L SGA + +FK+VG Sbjct: 243 AGALEEAGDLLQ---------AIAEGAIGREAISTELRDLLSGAGRRGDPGEITLFKSVG 293 Query: 295 QAAWDLAAAR 304 A DL AAR Sbjct: 294 YALEDLVAAR 303 >mlr2282 Non COG Length = 316 Score = 79.3 bits (194), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 76/259 (29%), Positives = 120/259 (46%), Gaps = 30/259 (11%) Query: 8 QTAQALPY--AALVDALARATQELAD-------GRIR-----APERQVVPIDAASVL--L 51 TA+ LPY +A++D LA +T E+ D G+ R AP+ V P D + L Sbjct: 2 NTAETLPYLSSAVLDRLAISTPEIVDEIERQIVGQRRGEVWCAPKAAVWPGDDRYFMATL 61 Query: 52 GMPAIADDLSVTKLITVHADNARHQLPAIQGEVIAFETQTGRRLALMDGPTVTARRTAAM 111 G+ + L+ TK + V+ NA L + + + +TG LAL+DG VTA+RTA + Sbjct: 62 GVATVPSVLA-TKSLVVNPRNAARGLATLNSLITLLDAETGLPLALVDGNWVTAKRTAGL 120 Query: 112 SMLGIRTLLPRQPQSALLIGTGVQSAAHADALVEFFGVRQFWIVARDLARTQAFCRALSE 171 S + R + S IG GVQ+ H +A + F +R+ R + +A C Sbjct: 121 SAVAARRMARHDASSVAFIGCGVQARGHLEAFADLFPLREIRAFGRGKSNREALCEMARS 180 Query: 172 RHPQAVASLLPTQMLQQDLPHTDVVIALTTSRSAVIPE---HIAADTLAIGVGAFKPDMV 228 R +A+ P + + D+V++ T ++PE + A+ L G D+ Sbjct: 181 RGLEAI----PCDTARAAVEGADMVVSTVT----LVPEPEPFLDANWLKPGSFTAITDLA 232 Query: 229 --EFPASLLHARRIVVDDL 245 P ++ RIVVDDL Sbjct: 233 LPWLPETMRRFDRIVVDDL 251 >SSO0378 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Sso Sulfolobus solfataricus Length = 309 Score = 75.9 bits (185), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 119/259 (45%), Gaps = 16/259 (6%) Query: 1 MHILDPRQTAQALPYAALVDALARATQELADGRIRAPERQVVPIDAASVLLGMPAIADDL 60 M IL + + L V ++ A + ++ P+R V+ + L MP+ D Sbjct: 1 MIILTRKDLDELLKAEIAVSSVKEAFKLHYQKKVDQPQRLVMSVKGNWWGL-MPSSTDYS 59 Query: 61 SVTKLITVHADNARHQLPAIQGEVIAFETQTGRRLALMDGPTVTARRTAAMSMLGIRTLL 120 VTK++ V +N LP +QG VI TG LA++DG T+TA RTAA S+L + Sbjct: 60 FVTKIVNVIPENKERGLPLVQGVVILMSPDTGEILAIIDGTTLTAIRTAAASILSTELAI 119 Query: 121 P-RQPQSALLIGTGVQSAAHADALVEFFGVRQFWIVARDLARTQAFCRALSERHPQAVAS 179 R +IG G ++ HA +E+F V++ +I AR + + R E A+ Sbjct: 120 NGRNIGILGIIGAGTEAYYHAKLALEYFKVQKLYISARK-SHFELAKRVGGE------AT 172 Query: 180 LLPTQMLQQDLPHTDVVIALTTSRSAVIPEHIAADTLAI-GVGAFKPDMVEF-PASLLHA 237 L T L ++D + A T+S V+ D + +GA PD E +++ Sbjct: 173 DLETL-----LKNSDTIFATTSSNFPVVLGKYLKDVFHLSSIGAHTPDSRELDDDTIIKV 227 Query: 238 RRIVVDDLAGAHHEAGDLI 256 + +VD L E+GD I Sbjct: 228 KSYIVDSLEAVSKESGDYI 246 >MA3252 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Mac Methanosarcina acetivorans str.C2A Length = 326 Score = 73.2 bits (178), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 67/275 (24%), Positives = 115/275 (41%), Gaps = 26/275 (9%) Query: 53 MPAI--ADDLSVTKLITVHADNARHQLPAIQGEVIAFETQTGRRLALMDGPTVTARRTAA 110 MPA +D++ K++ VH N LP + +I +TG +A+MDG +T RT A Sbjct: 56 MPAYLEEEDITGVKIVNVHPGNPMRNLPTVMALIILISPETGAPVAIMDGTYLTDIRTGA 115 Query: 111 MSMLGIRTLLPRQPQSALLIGTGVQSAAHADALVEFFGVRQFWIVARDLARTQAFCRALS 170 + + L + + L+G G Q+ +AL E F I +R F + +S Sbjct: 116 AGGVAAKYLARKDSKVIGLVGAGNQARTQLEALCEVFEPETVRITSRTKESCDQFIKEMS 175 Query: 171 ERHPQAVASLLPTQMLQQD----LPHTDVVIALTTSRSAVIPEHIAADTLAIG-VGAFKP 225 + +P ++L ++ + D+++ T +R ++ + I +GA Sbjct: 176 D--------FVPCEILYEESVEKVCDCDILVTTTPTRKPIVKASWVKEGTHINAIGADAV 227 Query: 226 DMVEFPASLLHARRIVVDDLAGAHHEAGDLIQAGVDWFGVVAI----ADVVAGRTPAATL 281 E LL +I+VDD+ A H + + I +V+ G P T Sbjct: 228 GKEELDPELLLRSKIIVDDMVQALHSGEVNVPLSKHYISENDIHAQLGEVIVGLKPGRT- 286 Query: 282 ASGAALPVFKTVGQAAWDLAAA-----RVMRATLG 311 S + +F + G A D+A A R +R LG Sbjct: 287 -SEEEITIFDSTGLAIQDVATAHMVYERAVREGLG 320 >AF1665 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Afu Archaeoglobus fulgidus Length = 322 Score = 68.6 bits (166), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 80/295 (27%), Positives = 128/295 (43%), Gaps = 18/295 (6%) Query: 19 VDALARATQELADGRIRAPERQVVPIDAASVLLGMPAIADDLSVTKLITVHADNARHQLP 78 ++A+ A + A G+ + P + + + L MPA + K + H N LP Sbjct: 21 MNAVEEAFRLYALGKAQMPPKVYLEFEKGD-LRAMPAHLMGYAGLKWVNSHPGNPDKGLP 79 Query: 79 AIQGEVIAFETQTGRRLALMDGPTVTARRTAAMSMLGIRTLLPRQPQSALLIGTGVQSAA 138 + +I +TG LA+MD T+ RT A + + L + IG G Q+ Sbjct: 80 TVMALMILNSPETGFPLAVMDATYTTSLRTGAAGGIAAKYLARKNSSVFGFIGCGTQAYF 139 Query: 139 HADALVEFFGVRQFWIVARDLARTQAFCRALSERHPQAV-ASLLPTQMLQQDLPHTDVVI 197 +AL F + + + A D+ R +A + +S + + AS+ P ++ DV++ Sbjct: 140 QLEALRRVFDIGE--VKAYDV-REKAAKKFVSYCEDRGISASVQPA----EEASRCDVLV 192 Query: 198 ALTTSRSAVIP-EHIAADTLAIGVGAFKPDMVEFPASLLHARRIVVDDLAGAHHEAGDLI 256 T SR V+ E + T +GA P E +L +IVVDDL A H G I Sbjct: 193 TTTPSRKPVVKAEWVEEGTHINAIGADGPGKQELDVEILKKAKIVVDDLEQAKH--GGEI 250 Query: 257 QAGVDWFGVVAIADVVA--GRTPAATL---ASGAALPVFKTVGQAAWDLAAARVM 306 V GV+ + DV A G A S + +F + G A D+A A+V+ Sbjct: 251 NVAVSK-GVIGVEDVHATIGEVIAGLKDGRESDEEITIFDSTGLAIQDVAVAKVV 304 >MTH1495 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Mth Methanothermobacter thermautotrophicus Length = 339 Score = 66.6 bits (161), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 70/263 (26%), Positives = 118/263 (44%), Gaps = 21/263 (7%) Query: 53 MPAIADDLSV--TKLITVHADNA-RHQLPAIQGEVIAFETQTGRRLALMDGPTVTARRTA 109 MP+ ++L + K + VH N RH LP + + + +TG +ALMDG +T RT Sbjct: 66 MPSYLEELEMAGVKCVNVHPSNPDRHSLPTVMAVIELVDPETGFPIALMDGTHITDMRTG 125 Query: 110 AMSMLGIRTLLPRQPQSALLIGTGVQSAAHADALVEFFGVRQFWIVARDLARTQAFC-RA 168 A + ++ L R +IG G Q+ A+ + + + R + + F RA Sbjct: 126 AAGGVSVKYLASRDASRLGIIGAGRQAWTQLMAISRVADLEEVSVYCRTPSTREKFALRA 185 Query: 169 LSERHPQAVASLLPTQMLQQDLPHTDVVIALTTSRSAVI-PEHIAADTLAIGVGAFKPDM 227 E A+ P + ++ D+V+ +T SRS V+ + ++ T +GA P Sbjct: 186 SKEYEVPVRAATDPREAVE----GMDIVVTVTPSRSPVVMADWVSPGTHICAMGADAPGK 241 Query: 228 VEFPASLLHARRIVVDDLAGAHHEAGDL---IQAGV----DWFGVVAIADVVAGRTPAAT 280 E +L R+ D L A H +G++ I G+ D G ++ DV+ G+ T Sbjct: 242 QELDPLILKNARVFYDSLEQATH-SGEINVPITEGILRVDDLQG--SLGDVMTGKIEGRT 298 Query: 281 LASGAALPVFKTVGQAAWDLAAA 303 S A + VF + G + D+ A Sbjct: 299 --SPADVTVFDSTGLSIQDITTA 319 >VNG2224G [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Hbs Halobacterium sp. NRC-1 Length = 291 Score = 63.2 bits (152), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 72/274 (26%), Positives = 115/274 (41%), Gaps = 39/274 (14%) Query: 53 MPAIAD----DLSVTKLITVHADN-ARHQLPAIQGEVIAFETQTGRRLALMDGPTVTARR 107 MPA D D + K + VH DN A H LP + G ++ + +T LALMDG +T +R Sbjct: 19 MPAYMDAGDWDAAGIKWVNVHPDNPADHDLPTVMGTMVYSDPETAFPLALMDGTELTMKR 78 Query: 108 TAAMSMLGIRTLLPRQPQSALLIGTGVQSAAHADALVEFFGVRQFWIVARDLART--QAF 165 T A + + L S ++G GVQ+ +A+ + + + +V D++ Q + Sbjct: 79 TGAAAAVATDHLAVADATSFGVVGAGVQAYTQLEAISKIRDIEE--VVVSDVSDDAVQQY 136 Query: 166 CRALSERHPQAVASLLPTQMLQQDLPHTDVVIALTTSRSAVIP-EHIAADTLAIGVGAFK 224 S+R S+ + H D++ +T ++ E + T +GA Sbjct: 137 VDHFSDRFDVRGGSI-------SEAGHCDILSTVTPVEDPIVTAEDVGDHTHINAMGADA 189 Query: 225 PDMVEFPASLLHARRIVVDDLAGAHHE------------AGDLIQAGVDWFGVVAIADVV 272 E +L A +V+DD A H A D I A I ++V Sbjct: 190 EGKHELADDILLAGTLVIDDHAQTTHSGEINVPYHEDTLADDDIDA--------EIGEIV 241 Query: 273 AGRTPAATLASGAALPVFKTVGQAAWDLAAARVM 306 G T + G + VF + G A D+AAA V+ Sbjct: 242 VGNADGRTDSDG--VTVFDSTGLAIQDVAAAHVV 273 >MK1411 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Mka Methanopyrus kandleri AV19 Length = 325 Score = 61.2 bits (147), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 73/274 (26%), Positives = 116/274 (42%), Gaps = 21/274 (7%) Query: 37 PERQVVPIDAASVLLGMPAIADDLSV--TKLITVHADNARHQLPAIQGEVIAFETQTGRR 94 P + +VP++ + MPA +L V K++ H DN LP + + E +TGR Sbjct: 35 PPKTIVPLEGGDFRV-MPAYLSELGVAGVKIVNSHPDNPDRGLPTVMAVMCLIEPETGRP 93 Query: 95 LALMDGPTVTARRTAAMSMLGIRTLLPRQPQSALLIGTGVQSAAHADALVEFFGVRQFWI 154 L L+ +T+ RT A + + L ++ ++G GVQ E F + ++ Sbjct: 94 LCLVSATEITSLRTGAAGAVASK-YLAEDVRTVGIVGAGVQGRYQLLTHAEVFDLEAVFV 152 Query: 155 V--ARDLARTQAFCRALSERHPQAVASLLPTQMLQQDLPHTDVVIALTTSRSAVI-PEHI 211 AR+ AR A ER A +L L DVV T + + E + Sbjct: 153 YDQAREAARRLA---EWVERDLGVDAKVLDN--LDFSGLDVDVVCTCTPATEPYLGSEDV 207 Query: 212 AADTLAIGVGAFKPDMVEFPASLLHARRIVVDDLAGAHHEAGDLIQ----AGVDWFGVVA 267 D +GA P+ E LL +VVDD E+GD+ Q ++ ++ Sbjct: 208 PEDVHVNAIGADAPEKQEVKTELLKRAVVVVDDREQC-VESGDVSQPVERGELNPEELIE 266 Query: 268 IADVVAGRTPAATLASGAALPVFKTVGQAAWDLA 301 ++DVV G T + + L VF + G A D+A Sbjct: 267 LSDVVRGETEVDS----SELTVFDSTGIAILDVA 296