BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0261.p (422 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 467 e-131 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 389 e-108 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 304 2e-82 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 301 1e-81 AGl1071 [GEPR] COG0477 Permeases of the major facilitator superf... 284 3e-76 Z5523 [GEPR] COG0477 Permeases of the major facilitator superfam... 281 2e-75 ECs4893 [GEPR] COG0477 Permeases of the major facilitator superf... 281 2e-75 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 281 2e-75 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 274 3e-73 proP [GEPR] COG0477 Permeases of the major facilitator superfami... 274 3e-73 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 467 bits (1202), Expect = e-131, Method: Compositional matrix adjust. Identities = 238/415 (57%), Positives = 309/415 (74%), Gaps = 2/415 (0%) Query: 2 SVSNQQRRRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGF 61 S ++R A+ ++GN EWFDFT+Y FFA +IA + FP+ N T+LLLA+ATFGVGF Sbjct: 12 QTSLPRQRHAVATAILGNAFEWFDFTLYGFFAPVIATVLFPSANPFTALLLAIATFGVGF 71 Query: 62 FMRPVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVARLL 121 RP+GGI+LGIYADR GR+ AL+++ LLMA+GT +I +APTY G+ AP+I V+ARLL Sbjct: 72 VTRPLGGIVLGIYADRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLL 131 Query: 122 QGFSAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAAALA 181 QGFSAGGEMG ATA+L E AP +RA+Y+SWIQAS+G+A++ GA +GT T+ LDA AL Sbjct: 132 QGFSAGGEMGGATAYLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALR 191 Query: 182 SWGWRLPFLLGIIIGPVGYYIRHHLEETPTFLE--EKDKTDSPLKEVIRNFPRETSASFS 239 +WGWR+PF LG++IGP+GY IR L+ETP F + + DSPL EV+R R S Sbjct: 192 AWGWRIPFALGVLIGPIGYVIRSRLDETPAFARAATEARADSPLLEVVRRHRRAVLIGAS 251 Query: 240 MVILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRLADRIGRRP 299 +VILWTVCTYVLLFYM TY++ VLKLP + GF M G+ +M+ AP+ G LADR+G + Sbjct: 252 IVILWTVCTYVLLFYMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLGYQR 311 Query: 300 LLSGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVL 359 +LSG+A ILVLAYP++AY+N AP+ TL+ Q+VFG L AAYTGPI AF++LFP KVL Sbjct: 312 VLSGAALAILVLAYPLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPTKVL 371 Query: 360 STGLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAISFVGTRFVR 414 STGLS AYNL V + GGFA F++TWL A +AP YVM+AA +S +GT ++R Sbjct: 372 STGLSTAYNLTVMLIGGFAPFYLTWLSHAFDPMLAPVLYVMVAALVSLIGTLWLR 426 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 389 bits (999), Expect = e-108, Method: Compositional matrix adjust. Identities = 209/414 (50%), Positives = 277/414 (66%), Gaps = 2/414 (0%) Query: 4 SNQQRRRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFM 63 S R R + A VIGN LEW+DF VY F + +IA+LFFP+G++ TSLL+A+ATFGVGFFM Sbjct: 6 SGTSRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFM 65 Query: 64 RPVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVARLLQG 123 RPVGG+LLG+YADR GRKAA+ + ILLM + MI APTY +IG+ APL+IV+AR+LQG Sbjct: 66 RPVGGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQG 125 Query: 124 FSAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAAALASW 183 F+ GGE SATAFL E AP R Y SW +AV GA +G VT LDA AL SW Sbjct: 126 FATGGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESW 185 Query: 184 GWRLPFLLGIIIGPVGYYIRHHLEETPTFLE--EKDKTDSPLKEVIRNFPRETSASFSMV 241 GWR+PFL G++IGPVG +IR ++ ET FLE + L V+R + R S + Sbjct: 186 GWRVPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLT 245 Query: 242 ILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRLADRIGRRPLL 301 ++ TV YV+L MPT++ K L LP F+ M + ++ P+ G L+DR+GRRP+L Sbjct: 246 VVGTVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVL 305 Query: 302 SGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVLST 361 + +++ YP+FA++ +APSL LL+ QL+ T I + GP A +E FP +V ST Sbjct: 306 LVATLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRST 365 Query: 362 GLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAISFVGTRFVRE 415 GL+VAYNLAV +FGGFA F +TWL GS +APAFYV+ AA + + T ++RE Sbjct: 366 GLAVAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLRE 419 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 304 bits (779), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 169/421 (40%), Positives = 240/421 (57%), Gaps = 5/421 (1%) Query: 5 NQQRRRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFMR 64 N+ + R+I V GN LE +DF VY ++A IA FFP N+ SL+L++ TFGVGF MR Sbjct: 7 NESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMR 66 Query: 65 PVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVARLLQGF 124 P+G ++LG Y DR GR+A L +T+ LMA GT +I L P Y +IGL APL++++ RLLQGF Sbjct: 67 PLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGF 126 Query: 125 SAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAAALASWG 184 SAG E+G + +L E + + ++ SW AS VAV+ A +G ++ L + WG Sbjct: 127 SAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWG 186 Query: 185 WRLPFLLGIIIGPVGYYIRHHLEETPTFLEEKDKTDSPLKEVIRNFP---RETSASFSMV 241 WR+PFL+G +I P + IR L+ET F + K + L E+ R+ R A +V Sbjct: 187 WRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHR--PALGEIFRSMGENWRLVGAGTLLV 244 Query: 242 ILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRLADRIGRRPLL 301 ++ TV Y++ Y PT+ VL L I + G P++G ++DRIGRRPLL Sbjct: 245 VMTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLL 304 Query: 302 SGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVLST 361 AL L+ AYP ++ + PS LL +L L +Y G ++ +E+ P V +T Sbjct: 305 ITFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTT 364 Query: 362 GLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAISFVGTRFVREPQYLQP 421 G S+AY+LA IFGGF TWLI ATG+ P ++ AA V T V +P Sbjct: 365 GFSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVKPAGRHV 424 Query: 422 H 422 H Sbjct: 425 H 425 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 301 bits (772), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 169/416 (40%), Positives = 240/416 (57%), Gaps = 5/416 (1%) Query: 5 NQQRRRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFMR 64 N+ + RAI V GN LE FDF VY ++A IA FFP GN SL+L++ TFG GF MR Sbjct: 7 NESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMR 66 Query: 65 PVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVARLLQGF 124 P+G I+LG Y DR GR+A L +T++LMA GT +I L P Y +IGL APL++++ RLLQGF Sbjct: 67 PLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGF 126 Query: 125 SAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAAALASWG 184 SAGGE G + +L+E A + +Y SW S VAV+ A +G ++ L + WG Sbjct: 127 SAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWG 186 Query: 185 WRLPFLLGIIIGPVGYYIRHHLEETPTFLEEKDKTDSPLKEVIRNFP---RETSASFSMV 241 WR+PFL+G +I P ++IR L ET F E+ K + E++R+ R A + Sbjct: 187 WRVPFLIGCLIVPFLFFIRRSLRETEEF--EQRKHRPTMGELLRSMGENWRLAGAGTLLA 244 Query: 242 ILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRLADRIGRRPLL 301 ++ TV Y++ Y PT+ VL + I + G ++ P++G L+DRIGRR L Sbjct: 245 VMTTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPL 304 Query: 302 SGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVLST 361 +AL L+ AYP ++ + PS LL +L L Y G ++ +E+ P ++ +T Sbjct: 305 IVFSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTT 364 Query: 362 GLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAISFVGTRFVREPQ 417 G S+AY+LA IFGGF T LI ATG+ P ++ AA V T V +PQ Sbjct: 365 GFSLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKPQ 420 >AGl1071 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 516 Score = 284 bits (726), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 160/427 (37%), Positives = 239/427 (55%), Gaps = 30/427 (7%) Query: 9 RRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFMRPVGG 68 ++A+ A +GN +EWFDF VY F A + K+FFP + A+ATF V F +RP+GG Sbjct: 34 KKAVTAAALGNAMEWFDFGVYGFVAYAVGKVFFPDAAPAVQTVAALATFSVPFLIRPLGG 93 Query: 69 ILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVARLLQGFSAGG 128 I G D+ GR+ LS+TI++MA T IGL P Y +IG++AP+++++ +L+QGFS GG Sbjct: 94 IFFGAMGDKFGRQKVLSLTIIIMAASTFCIGLIPGYATIGIWAPILLLLCKLVQGFSVGG 153 Query: 129 EMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAAALASWGWRLP 188 E A F+ EYAP+R+R Y SW+ +LGA + +++++ A WGWR+P Sbjct: 154 EYTGAAIFVAEYAPDRKRGYLGSWLDFGSIAGFVLGAGLVVLLSSAMGEAKFLDWGWRIP 213 Query: 189 FLLGIIIGPVGYYIRHHLEETPTFL------EEKDKTD------SPLKEVIRNFPRETSA 236 F L +G +G Y+RH EETP F EE+D+ P+ E+ R R + Sbjct: 214 FFLAAPLGLIGLYLRHAAEETPAFTERLQRAEEEDRQSLKERPMVPIAEIAREHFRSLAI 273 Query: 237 SFSMVILWTVCTYVLLFYMPTYSVKVLKLPQTTG---FIAGMVGGLCIMVLAPIVGRLAD 293 MV++ V Y+LL YMPTY K L + G IA MVG ++ + P +G L+D Sbjct: 274 CIGMVLVTNVTYYMLLTYMPTYLSKTLNYSEDHGVLIIIAVMVG---MLFVQPAIGLLSD 330 Query: 294 RIGRRPLLSGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYT-----GPILA 348 RIGR+P L+ + IL L+ P F I S + Q+ FG LI A G + + Sbjct: 331 RIGRKPFLAAGSTAILFLSLPAFHLIASGQ------VVQIFFGLLILAVALNCLIGIMAS 384 Query: 349 AFSELFPAKVLSTGLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAISFV 408 LFPA++ + L++A+N+++ I G WL+ T + PA+Y+M+AA V Sbjct: 385 TLPALFPARIRYSALAIAFNISI-IVAGLTPTVTAWLVEVTENIYMPAYYLMVAAVFGIV 443 Query: 409 GTRFVRE 415 T F++E Sbjct: 444 TTFFLKE 450 >Z5523 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 438 Score = 281 bits (720), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 169/427 (39%), Positives = 252/427 (59%), Gaps = 13/427 (3%) Query: 1 VSVSNQQR-RRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLT-SLLLAVATFG 58 VSV + RR I A+ GN LE+FDF VY+FF V I+ LFFP D +LLLA ATFG Sbjct: 9 VSVKKKPSGRRVIFASAFGNALEFFDFGVYNFFVVYISTLFFPPSADKNVALLLAFATFG 68 Query: 59 VGFFMRPVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVA 118 V FFMRP+GGI++G +ADR GRK A+ TI LM++GT MIG+APTYE+ G + +V+A Sbjct: 69 VSFFMRPLGGIIVGAWADRFGRKPAMVFTIALMSLGTLMIGIAPTYETAGYWGTATLVLA 128 Query: 119 RLLQGFSAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAA 178 RL+QG +AGGE+G++ + L E AP R +YSSW A+ G+A G V ++A L A Sbjct: 129 RLIQGVAAGGEVGASMSLLVESAPANRRGFYSSWSLATQGLATTFGGVVALGLSAWLPFA 188 Query: 179 A-----LASWGWRLPFLLGIIIGPVGYYIRHHLEET---PTFLEEKDKTDSPLKEVIRNF 230 +A WGWR+PF +G+++ PVG ++R LE P ++ ++S ++++ Sbjct: 189 TGSETVMAEWGWRVPFFIGVLLAPVGCWLRLSLENDVPEPAHNKKAAASESAFSLLMQH- 247 Query: 231 PRETSAS-FSMVILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVG 289 + T A+ + I TV TY+ LFY T++ K L + Q A ++ G+ V A +VG Sbjct: 248 -KATIANGILLAIGSTVATYISLFYYGTWAAKYLGMNQNYSHAAMLLAGVITFVGALLVG 306 Query: 290 RLADRIGRRPLLSGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAA 349 L D +GR+ L+ S ++L+ ++P F + + PS LL V + P++ Sbjct: 307 MLCDSVGRKKLILISRVMVLICSWPSFWLLVNYPSPGMLLTVVFVMVSFTTLGGVPVMLL 366 Query: 350 FSELFPAKVLSTGLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAISFVG 409 SEL P ++ + G ++ Y++ V IFGGFA +F T I S APA+Y+ +S + Sbjct: 367 ISELLPKRIRALGFALVYSIGVAIFGGFAQYFATQSIVLLDSLTAPAWYLGGGTLLSMLA 426 Query: 410 TRFVREP 416 +V+EP Sbjct: 427 LLYVKEP 433 >ECs4893 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 438 Score = 281 bits (720), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 169/427 (39%), Positives = 252/427 (59%), Gaps = 13/427 (3%) Query: 1 VSVSNQQR-RRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLT-SLLLAVATFG 58 VSV + RR I A+ GN LE+FDF VY+FF V I+ LFFP D +LLLA ATFG Sbjct: 9 VSVKKKPSGRRVIFASAFGNALEFFDFGVYNFFVVYISTLFFPPSADKNVALLLAFATFG 68 Query: 59 VGFFMRPVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVA 118 V FFMRP+GGI++G +ADR GRK A+ TI LM++GT MIG+APTYE+ G + +V+A Sbjct: 69 VSFFMRPLGGIIVGAWADRFGRKPAMVFTIALMSLGTLMIGIAPTYETAGYWGTATLVLA 128 Query: 119 RLLQGFSAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAA 178 RL+QG +AGGE+G++ + L E AP R +YSSW A+ G+A G V ++A L A Sbjct: 129 RLIQGVAAGGEVGASMSLLVESAPANRRGFYSSWSLATQGLATTFGGVVALGLSAWLPFA 188 Query: 179 A-----LASWGWRLPFLLGIIIGPVGYYIRHHLEET---PTFLEEKDKTDSPLKEVIRNF 230 +A WGWR+PF +G+++ PVG ++R LE P ++ ++S ++++ Sbjct: 189 TGSETVMAEWGWRVPFFIGVLLAPVGCWLRLSLENDVPEPAHNKKAAASESAFSLLMQH- 247 Query: 231 PRETSAS-FSMVILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVG 289 + T A+ + I TV TY+ LFY T++ K L + Q A ++ G+ V A +VG Sbjct: 248 -KATIANGILLAIGSTVATYISLFYYGTWAAKYLGMNQNYSHAAMLLAGVITFVGALLVG 306 Query: 290 RLADRIGRRPLLSGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAA 349 L D +GR+ L+ S ++L+ ++P F + + PS LL V + P++ Sbjct: 307 MLCDSVGRKKLILISRVMVLICSWPSFWLLVNYPSPGMLLTVVFVMVSFTTLGGVPVMLL 366 Query: 350 FSELFPAKVLSTGLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAISFVG 409 SEL P ++ + G ++ Y++ V IFGGFA +F T I S APA+Y+ +S + Sbjct: 367 ISELLPKRIRALGFALVYSIGVAIFGGFAQYFATQSIVLLDSLTAPAWYLGGGTLLSMLA 426 Query: 410 TRFVREP 416 +V+EP Sbjct: 427 LLYVKEP 433 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 281 bits (719), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 156/408 (38%), Positives = 236/408 (57%), Gaps = 5/408 (1%) Query: 11 AIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFMRPVGGIL 70 AI+ GN LE FDF ++ F+A IA+ FFP ++ SL+L A FG GF MRPVG I+ Sbjct: 16 AILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGSGFLMRPVGAIV 75 Query: 71 LGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVARLLQGFSAGGEM 130 LG Y DR+GR+ L VT+ +M GT +I L P Y++IGL AP ++++ RLLQGFSAG E+ Sbjct: 76 LGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGRLLQGFSAGVEL 135 Query: 131 GSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAAALASWGWRLPFL 190 G + +L+E A + +Y+SW AS VA+++ A +G + +L A++ WGWR+PF Sbjct: 136 GGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDAISEWGWRIPFF 195 Query: 191 LGIIIGPVGYYIRHHLEETPTFLEEKDKTDSP--LKEVIRNFPRETSASFSMVILWTVCT 248 +G +I P+ + +R L+ET FL+ K + D+ + +N+ R +A +V + T Sbjct: 196 IGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNW-RIITAGTLLVAMTTTTF 254 Query: 249 YVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRLADRIGRRPLLSGSAALI 308 Y + Y PTY VL L I M+ G+ + PI G ++DRIGRR +L G L Sbjct: 255 YFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMGITLLA 314 Query: 309 LVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVLSTGLSVAYN 368 L+ +P+ ++ +AP + + + L F Y G ++AA +E+ P V + G S+A++ Sbjct: 315 LITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFS 374 Query: 369 LAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAISFVGTR--FVR 414 LA IFGG T L+ TG +P +++M AA T FVR Sbjct: 375 LATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLFVR 422 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 274 bits (701), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 162/399 (40%), Positives = 235/399 (58%), Gaps = 7/399 (1%) Query: 4 SNQQRRRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFFM 63 SN+ + AI V GN LE +DF VY F+A IAK FFP N SL+L++ATFG GF M Sbjct: 3 SNKSKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLM 62 Query: 64 RPVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVARLLQG 123 RP+G + LG Y DR GR+ L +T+ LMA+GT +I P Y ++G+ APL+++ RLLQG Sbjct: 63 RPLGAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQG 122 Query: 124 FSAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAAALASW 183 FSAG E+G + +L+E A + ++ SW AS VAV+ +G + L + W Sbjct: 123 FSAGVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEW 182 Query: 184 GWRLPFLLGIIIGPVGYYIRHHLEETPTFLEEKDKTDSP-LKEVIRNFPRETS---ASFS 239 GWR+PF +G +I P + IR LEETP F + +T P L +V+R+ + A + Sbjct: 183 GWRVPFFIGCLIVPALFVIRRSLEETPEF---EARTHRPSLSQVLRSIGQNFGVVLAGTA 239 Query: 240 MVILWTVCTYVLLFYMPTYSVKVLKLPQTTGFIAGMVGGLCIMVLAPIVGRLADRIGRRP 299 MV++ TV Y++ Y PT+ L+L + M GL + P++G +DRIGR+P Sbjct: 240 MVVMTTVSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKP 299 Query: 300 LLSGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPILAAFSELFPAKVL 359 LL G++AL L+ AYP +++ PS + LL +L L ++Y G ++ A +E+ PA V Sbjct: 300 LLLGASALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVR 359 Query: 360 STGLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFY 398 +TG S+AY+LA FGGF TWLI + AP + Sbjct: 360 TTGFSLAYSLATATFGGFTPAVCTWLIHTLDNRAAPGIW 398 >proP [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 500 Score = 274 bits (700), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 149/429 (34%), Positives = 244/429 (56%), Gaps = 22/429 (5%) Query: 3 VSNQQRRRAIVATVIGNGLEWFDFTVYSFFAVIIAKLFFPTGNDLTSLLLAVATFGVGFF 62 + + + R+AI A +GN +EWFDF VY F A + K+FFP + ++ A+ATF V F Sbjct: 18 IDDGKLRKAITAASLGNAMEWFDFGVYGFVAYALGKVFFPGADPSVQMVAALATFSVPFL 77 Query: 63 MRPVGGILLGIYADRVGRKAALSVTILLMAVGTTMIGLAPTYESIGLFAPLIIVVARLLQ 122 +RP+GG+ G+ D+ GR+ L++TI++M++ T IGL P+Y++IG++AP+++++ ++ Q Sbjct: 78 IRPLGGLFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQ 137 Query: 123 GFSAGGEMGSATAFLTEYAPERERAYYSSWIQASIGVAVLLGAAVGTFVTASLDAAALAS 182 GFS GGE A+ F+ EY+P+R+R + SW+ +LGA V ++ + A Sbjct: 138 GFSVGGEYTGASIFVAEYSPDRKRGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLD 197 Query: 183 WGWRLPFLLGIIIGPVGYYIRHHLEETPTFLEEKDK---------TDSP---LKEVIRNF 230 WGWR+PF + + +G +G Y+RH LEETP F + DK D P KE+ + Sbjct: 198 WGWRIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKY 257 Query: 231 PRETSASFSMVILWTVCTYVLLFYMPTYSVKVLKLPQTTG---FIAGMVGGLCIMVLAPI 287 R +VI V Y+LL YMP+Y L + G IA M+G ++ + P+ Sbjct: 258 WRSLLTCIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIG---MLFVQPV 314 Query: 288 VGRLADRIGRRP-LLSGSAALILVLAYPMFAYINSAPSLSTLLIFQLVFGTLIAAYTGPI 346 +G L+DR GRRP +L GS AL VLA P F INS + + L+ ++ +TG + Sbjct: 315 MGLLSDRFGRRPFVLLGSVAL-FVLAIPAFILINSN-VIGLIFAGLLMLAVILNCFTGVM 372 Query: 347 LAAFSELFPAKVLSTGLSVAYNLAVTIFGGFASFFITWLIAATGSTMAPAFYVMIAAAIS 406 + +FP + + L+ A+N++V + G WL+ ++ + M PA+Y+M+ A + Sbjct: 373 ASTLPAMFPTHIRYSALAAAFNISVLV-AGLTPTLAAWLVESSQNLMMPAYYLMVVAVVG 431 Query: 407 FVGTRFVRE 415 + ++E Sbjct: 432 LITGVTMKE 440