BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0231.p (397 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0880 [C] COG0282 Acetate kinase Bme Brucella melitensis 223 7e-58 mlr6576 [C] COG0282 Acetate kinase Mlo Mesorhizobium loti 168 2e-41 SMb21184 [C] COG0282 Acetate kinase Sme Sinorhizobium meliloti 165 2e-40 RP110 [C] COG0282 Acetate kinase Rpr Rickettsia prowazekii 164 4e-40 SA1533 [C] COG0282 Acetate kinase Sau Staphylococcus aureus N315 156 1e-37 FN1171 [C] COG0282 Acetate kinase Fnu Fusobacterium nucleatum 152 1e-36 VC1098 [C] COG0282 Acetate kinase Vch Vibrio cholerae 152 1e-36 MA3606 [C] COG0282 Acetate kinase Mac Methanosarcina acetivorans... 152 1e-36 BS_ackA [C] COG0282 Acetate kinase Bsu Bacillus subtilis 149 1e-35 TM0274 [C] COG0282 Acetate kinase Tma Thermotoga maritima 149 1e-35 >BMEII0880 [C] COG0282 Acetate kinase Bme Brucella melitensis Length = 401 Score = 223 bits (567), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 111/249 (44%), Positives = 156/249 (62%) Query: 1 MNRLLLTFNAGSSTIKLGVFRLDGARARKIGQGQLDLHLTPLKLRLEIDGERSEVEIDAD 60 M + L+TFNAGSST+K+GVF D RK+ +G +DL +PL+ RL + ++ + A Sbjct: 1 MKKQLVTFNAGSSTVKIGVFECDENAVRKVSKGDIDLTGSPLRFRLRGENGNLDIVLSAS 60 Query: 61 PAAAMDRVLEQVLHQLEVGHAQGELCAVGHRVVHGGLHLAQAVRLDDAIETELENLAPLA 120 A + +L ++ +L + AVGHRVV GG AQAV +DD +E L+ A Sbjct: 61 GADEITTILGELFDKLAEHIDPSRILAVGHRVVFGGDDFAQAVLIDDDNLEAIERLSIFA 120 Query: 121 PLHQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEEGVLRYGFHG 180 PLHQP++L LI+A+ ++ P L QTASFDTAFH + RRFA+P+ LH+ G+ R+GFHG Sbjct: 121 PLHQPKSLALIKAVRKIFPHLAQTASFDTAFHQTIPDTVRRFAIPQELHDRGIKRFGFHG 180 Query: 181 ISYSYVAAEMRRQALSEAHARVVVAHLGNGASLCALHAGRSVDASTGFSTLDGVPMGTRC 240 +SY V ++A A +++ AHLG+GASLCA+H +S+D S FSTLDG+PM TRC Sbjct: 181 LSYKSVIGNFSQRAPELAEGKIIAAHLGSGASLCAMHKRKSLDTSMSFSTLDGIPMATRC 240 Query: 241 ARSMPACCC 249 P Sbjct: 241 GALDPGVLL 249 >mlr6576 [C] COG0282 Acetate kinase Mlo Mesorhizobium loti Length = 401 Score = 168 bits (426), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 100/250 (40%), Positives = 138/250 (55%), Gaps = 2/250 (0%) Query: 1 MNRLLLTFNAGSSTIKLGVFRLDGARARKIGQGQLDLHLTPLKLRLEIDGERSEVEIDAD 60 M +L N GSS++K VF G A + L P +LR++ RS+++ D Sbjct: 1 MTDAILVLNGGSSSLKFAVFERHGELALLLRGNVSSLGQQP-RLRVDAAAGRSKIDRSLD 59 Query: 61 PA-AAMDRVLEQVLHQLEVGHAQGELCAVGHRVVHGGLHLAQAVRLDDAIETELENLAPL 119 A M + V L + VGHR+VHGG +A LD+ L L PL Sbjct: 60 EAPIGMGKAFAAVASVLAENDLLRRIDRVGHRIVHGGRDFTEATLLDERTLKALRLLEPL 119 Query: 120 APLHQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEEGVLRYGFH 179 AP+HQ NL ++ A L P Q FDTAFH+++ LA+ + LPR + E G++ YGFH Sbjct: 120 APIHQRINLEIVALAAELLPQALQIGCFDTAFHSTRPELAKIYGLPRAMTEAGIVSYGFH 179 Query: 180 GISYSYVAAEMRRQALSEAHARVVVAHLGNGASLCALHAGRSVDASTGFSTLDGVPMGTR 239 G+SYS++AA++ + + A R +VAHLG+GASLCA+ AGRSV + GFSTLDG+ M TR Sbjct: 180 GLSYSHIAAKLHDRYGAGAGGRTIVAHLGSGASLCAMDAGRSVATTMGFSTLDGLVMSTR 239 Query: 240 CARSMPACCC 249 C P Sbjct: 240 CGALDPGVIL 249 >SMb21184 [C] COG0282 Acetate kinase Sme Sinorhizobium meliloti Length = 392 Score = 165 bits (417), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 102/247 (41%), Positives = 137/247 (55%), Gaps = 3/247 (1%) Query: 5 LLTFNAGSSTIKLGVFRLDGARARKIGQGQLDLHLTPLKLR-LEIDG-ERSEVEIDADPA 62 LL NAGSS++K +F + A + + +LD T +L+ DG E +DA Sbjct: 4 LLVINAGSSSLKFQIFGIATAGLERQVRAKLDGIATQPRLKATAADGTELINRRLDATAV 63 Query: 63 AAMDRVLEQVLHQLEVGHAQGELCAVGHRVVHGGLHLAQAVRLDDAIETELENLAPLAPL 122 + L L +L A+GHRVVHGG + V ++ + L + LAPL Sbjct: 64 PDLPEALSVARDWLATLRGF-DLRAIGHRVVHGGPDYVRPVLIETTVLDRLASYQDLAPL 122 Query: 123 HQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEEGVLRYGFHGIS 182 HQP NL IR ++P + Q A FDTAFH + +ALPR +E+GV RYGFHGIS Sbjct: 123 HQPNNLAPIRLAMDIKPDVPQVACFDTAFHRGRTEHTDCYALPRTFYEQGVRRYGFHGIS 182 Query: 183 YSYVAAEMRRQALSEAHARVVVAHLGNGASLCALHAGRSVDASTGFSTLDGVPMGTRCAR 242 Y Y+A +R A A RV+VAHLG+GAS+CAL GRSV+ + GF+ LDG+PMGTR + Sbjct: 183 YEYIAGRLREVAPEVARGRVIVAHLGSGASMCALKDGRSVETTMGFTALDGLPMGTRPGQ 242 Query: 243 SMPACCC 249 P Sbjct: 243 LDPGVVL 249 >RP110 [C] COG0282 Acetate kinase Rpr Rickettsia prowazekii Length = 385 Score = 164 bits (414), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 87/265 (32%), Positives = 141/265 (53%), Gaps = 8/265 (3%) Query: 1 MNRLLLTFNAGSSTIKLGVFRLDGARAR-KIGQGQLDLHLTPLKLRLEIDGER-SEVEID 58 M ++L NAGSS++K+ +F + R KI + L K+ I+ ++ S I Sbjct: 1 MKDVILIANAGSSSLKISIFAIQNKRVNDKIYN--IFLEKNNNKILFYINQQKESTTSIK 58 Query: 59 ADPAAAMDRVLEQVLHQLEVGHAQGELCAVGHRVVHGGLHLAQAVRLDDAIETELENLAP 118 DP M + E+ + + L A GHR+VHGG + + V ++ + EL L P Sbjct: 59 DDPIEMMINLFEEWWKK----QSALNLIATGHRIVHGGKNFNKPVVVNKKVIKELRVLIP 114 Query: 119 LAPLHQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEEGVLRYGF 178 L+PLHQP NL+++ + + FDT+FH + + + F LP++ +++G++RYGF Sbjct: 115 LSPLHQPYNLQVLDLFFQKYKAISHIICFDTSFHCTNSPITKAFGLPKQYYDKGIMRYGF 174 Query: 179 HGISYSYVAAEMRRQALSEAHARVVVAHLGNGASLCALHAGRSVDASTGFSTLDGVPMGT 238 HG+SY YV++ + + + + ++AHLG+G+SLCA+ G S+ +S GFS LDGV M T Sbjct: 175 HGLSYQYVSSHFKEITMEDLPPKAIIAHLGSGSSLCAIKNGLSLTSSMGFSVLDGVMMAT 234 Query: 239 RCARSMPACCCTCCARGCRWMNWKT 263 R P +N T Sbjct: 235 RPGNLDPGVVLYLINNEKMTINEIT 259 >SA1533 [C] COG0282 Acetate kinase Sau Staphylococcus aureus N315 Length = 400 Score = 156 bits (394), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 92/254 (36%), Positives = 145/254 (57%), Gaps = 11/254 (4%) Query: 1 MNRLLLTFNAGSSTIKLGVFRLDGARARKIGQGQLD-LHLTPLKLRLEIDGERSEVEID- 58 M++L+L NAGSS++K + R+ + +G ++ + L +E++GE+ + D Sbjct: 1 MSKLILAINAGSSSLKFQLIRM--PEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDI 58 Query: 59 ADPAAAMDRVLEQVLHQLEVGHAQGELCAVGHRVVHGGLHLAQAVRLDDAIETELENLAP 118 D A+D +L+ + + ++ GHRVVHGG ++V + D +E E+E L+ Sbjct: 59 KDHVEAVDIMLD-AFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSE 117 Query: 119 LAPLHQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEE-GVLRYG 177 LAPLH P NL IRA +L P + A FDTAFH + A ++LP +++ G+ +YG Sbjct: 118 LAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYG 177 Query: 178 FHGISYSYV---AAEMRRQALSEAHARVVVAHLGNGASLCALHAGRSVDASTGFSTLDGV 234 FHG S+ +V AAEM + + + R++ H+GNGAS+ A+ G+S+D S GF+ L GV Sbjct: 178 FHGTSHKFVSQRAAEMLDKPIED--LRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGV 235 Query: 235 PMGTRCARSMPACC 248 MGTR PA Sbjct: 236 TMGTRSGNIDPALI 249 >FN1171 [C] COG0282 Acetate kinase Fnu Fusobacterium nucleatum Length = 398 Score = 152 bits (384), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 90/218 (41%), Positives = 122/218 (55%), Gaps = 14/218 (6%) Query: 45 RLEIDGERSEVEIDAD--------PAAAMDRVLEQVLHQL---EVG--HAQGELCAVGHR 91 R+ IDG + E E+ A P + LE V+ L E+G + E+ A+GHR Sbjct: 33 RIGIDGSKLEYEVVAKDFEKKLETPMPSHKEALELVISHLTDKEIGVIASVDEVDAIGHR 92 Query: 92 VVHGGLHLAQAVRLDDAIETELENLAPLAPLHQPQNLRLIRAIARLRPGLQQTASFDTAF 151 VVHGG AQ+V ++DA+ +E LAPLH P NL IR L PG + A FDTAF Sbjct: 93 VVHGGEEFAQSVLINDAVLKAIEANNDLAPLHNPANLMGIRTCMELMPGKKNVAVFDTAF 152 Query: 152 HASQDALARRFALPRRLHEE-GVLRYGFHGISYSYVAAEMRRQALSEAHARVVVAHLGNG 210 H + A + LP ++E V +YGFHG S+ YV+ MR + H++++V HLGNG Sbjct: 153 HQTMKPEAFMYPLPYEDYKELKVRKYGFHGTSHLYVSGIMREIMGNPEHSKIIVCHLGNG 212 Query: 211 ASLCALHAGRSVDASTGFSTLDGVPMGTRCARSMPACC 248 AS+ A+ G+SVD S G + L G+ MGTRC PA Sbjct: 213 ASITAVKDGKSVDTSMGLTPLQGLMMGTRCGDIDPAAV 250 >VC1098 [C] COG0282 Acetate kinase Vch Vibrio cholerae Length = 398 Score = 152 bits (384), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 93/252 (36%), Positives = 137/252 (54%), Gaps = 8/252 (3%) Query: 1 MNRLLLTFNAGSSTIKLGVFRLDGARARKIGQGQLDLHLTPLKLRLEIDGERSEVEIDAD 60 M++L+L N GSS++K V G + LHL +++ ++DG+ E Sbjct: 1 MSKLVLVLNCGSSSLKFAVVDAQSGEQHLSGLAEC-LHLPEARIKWKLDGKH---EAQLG 56 Query: 61 PAAAMDRVLEQVLHQLEVGHAQ--GELCAVGHRVVHGGLHLAQAVRLDDAIETELENLAP 118 AA D L ++ + + +L A+GHRVVHGG Q+ +DDA+ +E+ A Sbjct: 57 EGAAHDEALSFIVETILASKPELAAQLKAIGHRVVHGGEQFTQSALIDDAVLKGIEDCAA 116 Query: 119 LAPLHQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEE-GVLRYG 177 LAPLH P ++ I+A + P L+ A FDTAFH + A +ALP L++E G+ RYG Sbjct: 117 LAPLHNPAHIIGIKAAQKAFPELKNVAVFDTAFHQTMPEEAYLYALPYNLYKEHGIRRYG 176 Query: 178 FHGISYSYVAAE-MRRQALSEAHARVVVAHLGNGASLCALHAGRSVDASTGFSTLDGVPM 236 HG S+ ++A E R ++ HLGNGAS+CA+ G+SVD S G + L+G+ M Sbjct: 177 MHGTSHLFIAREAAERLGKPANELNIINCHLGNGASVCAIKNGQSVDTSMGLTPLEGLVM 236 Query: 237 GTRCARSMPACC 248 GTRC PA Sbjct: 237 GTRCGDIDPAII 248 >MA3606 [C] COG0282 Acetate kinase Mac Methanosarcina acetivorans str.C2A Length = 408 Score = 152 bits (384), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 94/254 (37%), Positives = 142/254 (55%), Gaps = 16/254 (6%) Query: 5 LLTFNAGSSTIKLGVFRLDGARARKIGQGQ---LDLHLTPLKLRLEIDGERSEVEIDA-D 60 +L NAGSS++K + + IG + +D + K DG++ E + D + Sbjct: 3 VLVINAGSSSLKYQLIDMTNESPLAIGLCERIGIDNSIITQKRS---DGKKLEKQTDLPN 59 Query: 61 PAAAMDRVLEQVLH-QLEVGHAQGELCAVGHRVVHGGLHLAQAVRLDDAIETELENLAPL 119 A++ V++ + +L V + E+ AVGHRVVHGG + +D+ +E +++ L Sbjct: 60 HKVALEEVVKALTDSELGVIKSMDEINAVGHRVVHGGEKFTSSALIDEGVEQAIKDCFEL 119 Query: 120 APLHQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEE-GVLRYGF 178 APLH P N+ I A + PG+ A FDTAFH + A A +ALP L+E+ G+ +YGF Sbjct: 120 APLHNPPNMMGITACQEIMPGVPMVAVFDTAFHQTIPAYAYMYALPYTLYEKYGIRKYGF 179 Query: 179 HGISYSYVAAEMRRQALS----EAHARVVVAHLGNGASLCALHAGRSVDASTGFSTLDGV 234 HG S+ YVA RR A E +V+ HLGNG+S+ A++ G+SV+ + GF+ L+GV Sbjct: 180 HGTSHFYVA---RRAAAMLGKPEEEVKVITCHLGNGSSITAVNGGKSVETTMGFTPLEGV 236 Query: 235 PMGTRCARSMPACC 248 MGTRC PA Sbjct: 237 AMGTRCGSIDPAVV 250 >BS_ackA [C] COG0282 Acetate kinase Bsu Bacillus subtilis Length = 395 Score = 149 bits (376), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 88/250 (35%), Positives = 141/250 (56%), Gaps = 11/250 (4%) Query: 5 LLTFNAGSSTIKLGVFRLDGARARKIGQGQLD-LHLTPLKLRLEIDGER-SEVEIDADPA 62 ++ NAGSS++K +F + + +G ++ + + + ++GE+ +EV D A Sbjct: 4 IIAINAGSSSLKFQLFEMPSETV--LTKGLVERIGIADSVFTISVNGEKNTEVTDIPDHA 61 Query: 63 AAMDRVLEQVLHQLEVGHAQGELCAVGHRVVHGGLHLAQAVRLDDAIETELENLAPLAPL 122 A+ +L + L + + E+ +GHRVVHGG + +V L D E+E+++ LAPL Sbjct: 62 VAVKMLLNK-LTEFGIIKDLNEIDGIGHRVVHGGEKFSDSVLLTDETIKEIEDISELAPL 120 Query: 123 HQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEE-GVLRYGFHGI 181 H P N+ I+A + P + A FDTAFH + + ++LP +E+ G+ +YGFHG Sbjct: 121 HNPANIVGIKAFKEVLPNVPAVAVFDTAFHQTMPEQSYLYSLPYEYYEKFGIRKYGFHGT 180 Query: 182 SYSYV---AAEMRRQALSEAHARVVVAHLGNGASLCALHAGRSVDASTGFSTLDGVPMGT 238 S+ YV AAE+ + L + R++ HLGNGAS+ A+ G+S+D S GF+ L GV MGT Sbjct: 181 SHKYVTERAAELLGRPLKD--LRLISCHLGNGASIAAVEGGKSIDTSMGFTPLAGVAMGT 238 Query: 239 RCARSMPACC 248 R PA Sbjct: 239 RSGNIDPALI 248 >TM0274 [C] COG0282 Acetate kinase Tma Thermotoga maritima Length = 403 Score = 149 bits (375), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 94/256 (36%), Positives = 144/256 (56%), Gaps = 23/256 (8%) Query: 5 LLTFNAGSSTIKLGVFRLDGAR------ARKIG-QGQLDLHLTPLKLRLEIDGERSEVEI 57 +L N+GSS+IK + ++G + A +IG +G +H + E+ +E Sbjct: 3 VLVINSGSSSIKYQLIEMEGEKVLCKGIAERIGIEGSRLVH--------RVGDEKHVIER 54 Query: 58 DA-DPAAAMDRVLEQVL-HQLEVGHAQGELCAVGHRVVHGGLHLAQAVRLDDAIETELEN 115 + D A+ +L ++ +L V E+ AVGHRVVHGG ++V +D+ + +E Sbjct: 55 ELPDHEEALKLILNTLVDEKLGVIKDLKEIDAVGHRVVHGGERFKESVLVDEEVLKAIEE 114 Query: 116 LAPLAPLHQPQNLRLIRAIARLRPGLQQTASFDTAFHASQDALARRFALPRRLHEE-GVL 174 ++PLAPLH P NL I+A +L PG+ A FDTAFH + A +A+P +E+ + Sbjct: 115 VSPLAPLHNPANLMGIKAAMKLLPGVPNVAVFDTAFHQTIPQKAYLYAIPYEYYEKYKIR 174 Query: 175 RYGFHGISYSYV---AAEMRRQALSEAHARVVVAHLGNGASLCALHAGRSVDASTGFSTL 231 RYGFHG S+ YV AAE+ + L E +++ H+GNGAS+ A+ G+ VD S GF+ L Sbjct: 175 RYGFHGTSHRYVSKRAAEILGKKLEE--LKIITCHIGNGASVAAVKYGKCVDTSMGFTPL 232 Query: 232 DGVPMGTRCARSMPAC 247 +G+ MGTR PA Sbjct: 233 EGLVMGTRSGDLDPAI 248