BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0226.p (1047 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3676 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1051 0.0 RSc1654 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 969 0.0 SMb20345 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizob... 883 0.0 mlr7298 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 872 0.0 mlr2404 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 865 0.0 mll5518 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 862 0.0 AGpA548 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacteri... 859 0.0 PA0158 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 850 0.0 BMEII0382 [V] COG0841 Cation/multidrug efflux pump Bme Brucella ... 848 0.0 AGl2075 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacteri... 822 0.0 >PA3676 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1025 Score = 1051 bits (2718), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/1030 (52%), Positives = 727/1030 (70%), Gaps = 11/1030 (1%) Query: 7 FNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQVQ 66 FNLSAW LQ++ +V +++ L+ +G SYS+L QSEDPPFTFK MV+QT+WPGA+A +V Sbjct: 3 FNLSAWALQNRQIVLYLMILLGAVGALSYSKLGQSEDPPFTFKAMVVQTNWPGASAEEVA 62 Query: 67 EQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMAA 126 Q+T+RI +KL ET D D + S+SR G SQ+ F ++ +S++P+ WYQ+RKK+ D+ A Sbjct: 63 RQVTERIEKKLMETGDYDRIVSFSRPGVSQVTFMAREDIHSSEIPELWYQIRKKISDIRA 122 Query: 127 TLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFGE 186 TLPQ ++GP+FNDEFG Y NIYAL G GF A ++DYAD+L+ +L + V K++ G Sbjct: 123 TLPQSIQGPFFNDEFGTTYGNIYALTGKGFDYAVMKDYADRLQLQLQRIRNVGKVELIGL 182 Query: 187 RNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNLRA 246 ++E I+ID+ N ++ LG+ + A+ QNAV G T +DRV +R +G+FD++ Sbjct: 183 QDEKIWIDLSNTKLATLGLPLAAVQKALEEQNAVASSGFFETASDRVQLRVSGRFDSVEE 242 Query: 247 LEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLGKAL 306 + + I++ +R+FR+GD+A + RG+++P MR G+ +G+ V M+PGGD++ LGKAL Sbjct: 243 IRDFPIRVGDRTFRIGDVAEVRRGFNDPPAPRMRFMGEDAIGLAVAMKPGGDILVLGKAL 302 Query: 307 DARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGMV 366 + L++ LPAGL L VS P AV V +F+ +AEA+ IVL+VS SLG+RTG+V Sbjct: 303 ETEFARLQQSLPAGLELRKVSDQPAAVRTGVGEFIRVLAEALVIVLLVSFFSLGLRTGLV 362 Query: 367 VVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNRR 426 V +SIP+VLA+T M+ F IGLHK+SLG LVLALGLLVDDAIIAVEMMAVK+EQG++R Sbjct: 363 VALSIPLVLAMTFAAMHYFGIGLHKISLGALVLALGLLVDDAIIAVEMMAVKMEQGYDRL 422 Query: 427 RAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVVL 486 +AA+FA+TSTAFPMLTGTL+T AGFLPIA A+SGTGEYTRS+F+V IAL++SW AAVV Sbjct: 423 KAASFAWTSTAFPMLTGTLITAAGFLPIATAQSGTGEYTRSLFQVVTIALVVSWFAAVVF 482 Query: 487 IPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRGR 546 +P LG +L + ++ A H G D P Y T Y RR V WCV +R Sbjct: 483 VPYLGAKLLPDLA------RLHAQKHGG--SADGYDP-YATAFYQRFRRLVEWCVRYRKT 533 Query: 547 VVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLKD 606 V++ T F+G+L F LVPQQFFP S R ELL+D+ L E AS +T E R+E +L+ Sbjct: 534 VIVLTLAAFVGALLLFRLVPQQFFPPSARLELLLDIKLAEGASLRSTGEEVQRLEKMLQG 593 Query: 607 RPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRRQFS 666 ID+YV++VG G+PRFYLPLDQQL + +FAQ VV AK +E REAL + L E + F Sbjct: 594 HDGIDNYVAYVGTGSPRFYLPLDQQLPAASFAQVVVLAKDLESREALRKWLIERMNEDFP 653 Query: 667 GARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWDEPAQ 726 R+R++RLENGPPVG+PVQFR+SGE IP+VR +A +VA +MR+ N+ DW+EP+ Sbjct: 654 HLRSRISRLENGPPVGYPVQFRVSGEDIPQVRELARKVADKMRENPHVVNVHLDWEEPS- 712 Query: 727 RSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSERVDPA 786 + V IDQ+RA LG+S+ +S FL L+G ++ +RE ++LI + LR ER D + Sbjct: 713 KVVYLSIDQERARALGVSTASLSQFLQSALTGSHVSFFREDNELIEILLRGTEQERRDLS 772 Query: 787 RLATLSMPTANG-PVPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDVTNDV 845 L +L++PT NG V L+ + E G+IW RNR PT+TV AD+ + + Sbjct: 773 LLPSLAVPTENGRSVALSQIATLEYGFEEGIIWHRNRLPTVTVRADIYDDSLPATLVAQI 832 Query: 846 NQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFGRTMM 905 L +RAELP GY ++VGG VE+ AK QSS++A +PL ++ VL LLMVQL+SF R M Sbjct: 833 APTLEPIRAELPDGYLLEVGGTVEDAAKGQSSVNAGVPLFIVVVLSLLMVQLRSFSRMAM 892 Query: 906 VVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGRF 965 V +TAPLGLIGV LLLF QPFGFVAMLGTIA+ G+IMRNSVILVDQIEQDI+ G R+ Sbjct: 893 VFLTAPLGLIGVTLFLLLFRQPFGFVAMLGTIALAGMIMRNSVILVDQIEQDISHGLDRW 952 Query: 966 DAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPALY 1025 AI+ ATVRRFRPI LTA AAVLA+IPL RS FFGPMA A+MGG+ +AT+LTL +LPALY Sbjct: 953 HAIIEATVRRFRPIVLTALAAVLAMIPLSRSVFFGPMAVAIMGGLIVATVLTLLFLPALY 1012 Query: 1026 ALCYRVKPDE 1035 A +RVK DE Sbjct: 1013 AAWFRVKKDE 1022 >RSc1654 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1039 Score = 969 bits (2505), Expect = 0.0, Method: Compositional matrix adjust. Identities = 510/1040 (49%), Positives = 680/1040 (65%), Gaps = 29/1040 (2%) Query: 6 RFNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQV 65 RFNLS W L+HQ L F+L + L GI +Y++L Q EDPPFTF+ MV+Q WPGATA Q+ Sbjct: 5 RFNLSRWALEHQPLTRFLLVALLLGGIFAYTQLGQDEDPPFTFRAMVVQAFWPGATAEQM 64 Query: 66 QEQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMA 125 Q+TD+I + LQE P +RSYS+ G++ + F + DT+P Q WY VRKKVGD+A Sbjct: 65 SRQVTDKIEKALQEVPYAWKIRSYSKPGETLVTFQLADTSPTKDTQQLWYTVRKKVGDIA 124 Query: 126 ATLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFG 185 ++LP GV+GPYFND+FGDVY +IYAL+ DGF+ QL DYAD +R +LL VP VAK+ G Sbjct: 125 SSLPTGVRGPYFNDDFGDVYGSIYALSADGFTYRQLNDYADAIRQQLLRVPNVAKVTLLG 184 Query: 186 ERNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNLR 245 +++E IYI+ A+ ++G+ +A+ I QN + P G++ T D V +R +GQF ++R Sbjct: 185 DQDEKIYIEFQQAKFAQMGLDINSIANQIAQQNNIGPSGVLVTPTDNVQIRLSGQFSDIR 244 Query: 246 ALEEKIIQ--INNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLG 303 LE ++ + RLGDIATI GY +P MR NG+ V+G+G++M GGD+I+LG Sbjct: 245 DLENLTLRGPGGTSNIRLGDIATIRHGYIDPPRAKMRFNGKEVIGLGISMAKGGDIIQLG 304 Query: 304 KALDARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRT 363 K L A E +R +LP G+ + V P +V+ SV +F+ + EAV IVL VS +SLG+ T Sbjct: 305 KDLRATVERIRAKLPVGIEMQQVQDQPQSVQHSVGEFVHVLIEAVVIVLAVSFLSLGLHT 364 Query: 364 ----------GMVVVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVE 413 G+VV ++IP+VLAVT LFM +FDIGLHK+SLG L++ALGLLVDDAIIAVE Sbjct: 365 KPRLRIDVWPGLVVGLTIPLVLAVTFLFMNIFDIGLHKISLGALIIALGLLVDDAIIAVE 424 Query: 414 MMAVKLEQGWNRRRAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSA 473 MM KLE+G+++ AA FAYTSTA PMLTGTL+T GFLP+ LA+S GEYT IF V+A Sbjct: 425 MMVRKLEEGFSKMEAATFAYTSTAMPMLTGTLITATGFLPVGLARSTVGEYTFGIFAVTA 484 Query: 474 IALLLSWLAAVVLIPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWL 533 +AL+LSW+AAVV +P LGY +L K H + H ++ T Y Sbjct: 485 LALVLSWVAAVVFVPYLGYLLLHTK---------------SHVGDGGHHELFDTPFYNRF 529 Query: 534 RRSVAWCVAFRGRVVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEAT 593 R V WCV +R V++ T F+ + F V +QFFP S RPEL+++L LPE ASF T Sbjct: 530 RGWVNWCVEYRKTVIVITLAAFVLGVFGFKYVEKQFFPDSSRPELMVELWLPEGASFGQT 589 Query: 594 QREAVRMEALLKDRPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREAL 653 + EA R EAL++ + ++ F+G GAPRFYLPLDQ L N AQ +V S+E RE + Sbjct: 590 EAEAKRFEALIRQQKSVESVAFFIGSGAPRFYLPLDQILPQTNVAQAIVMPTSLETREDV 649 Query: 654 ARALEEPLRRQFSGARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESR 713 + + L+ QF R R+ L NGPPV +PVQFR+ G I VR IA+QV A M+ Sbjct: 650 RQEIIGLLKSQFPQLRGRVKLLPNGPPVPYPVQFRVMGPDIGGVRKIADQVKAIMQANPN 709 Query: 714 ATNIQFDWDEPAQRSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISV 773 + +W+E + + +IDQ +A LG+++ I+ +SG I QYR+ DKL+ + Sbjct: 710 TVGVNDNWNENV-KLLRLDIDQDKARALGVTTGSIAQVTQTVMSGAPIAQYRDGDKLLDI 768 Query: 774 DLRAPRSERVDPARLATLSMPTANGP-VPLATLGQFNNTLEYGVIWERNRQPTITVLADV 832 +R ER L + +PTA+G VPL + + E GVIW NR ITV +DV Sbjct: 769 VMRPQERERNTLDALQNVQVPTASGRVVPLTQVARVGFAWEPGVIWRENRDYGITVQSDV 828 Query: 833 RPGVQGIDVTNDVNQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLL 892 GVQG VT +N L+ +RA+LP Y+I + G EE+A A +SI AQMPL + + L Sbjct: 829 VDGVQGPTVTAQINPLLDKIRADLPPDYQIKIAGAEEESANAGASIVAQMPLCIFIIFTL 888 Query: 893 LMVQLQSFGRTMMVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVD 952 LM+QL SF R++MV +T PLGLIG LLL P GFVA LG A++G+I+RNSVILVD Sbjct: 889 LMLQLHSFSRSVMVFLTGPLGLIGAAATLLLLRAPMGFVAQLGITALIGMIIRNSVILVD 948 Query: 953 QIEQDIAAGRGRFDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITI 1012 QIEQD+A G + AIV A VRRFRPI LTAAAAVLA+IPL RS F+GPMA A+MGG+ + Sbjct: 949 QIEQDVATGVPTWTAIVEAAVRRFRPIILTAAAAVLAMIPLSRSVFWGPMAAAIMGGLIV 1008 Query: 1013 ATILTLFYLPALYALCYRVK 1032 AT+LTL +LPALYA +RVK Sbjct: 1009 ATVLTLLFLPALYAAWFRVK 1028 >SMb20345 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1049 Score = 883 bits (2281), Expect = 0.0, Method: Compositional matrix adjust. Identities = 463/1049 (44%), Positives = 666/1049 (63%), Gaps = 26/1049 (2%) Query: 7 FNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQVQ 66 FNLS W + H ++ F+LAL+ + G R+ Q EDP FTF+VMV+Q WPGA+ ++++ Sbjct: 11 FNLSRWAIGHPSIARFLLALIIITGGLGLLRMGQREDPEFTFRVMVVQAVWPGASIQEME 70 Query: 67 EQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMAA 126 +Q+ ++I RKLQETP +DF+RSY+RAG + + I+ A +V +YQVRKKVGD+A Sbjct: 71 DQVVNKIERKLQETPHLDFVRSYTRAGSAIITVQIEGDTNADEVADAFYQVRKKVGDIAN 130 Query: 127 TLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFGE 186 LP+GV GPYFNDEFGD + +++++GDGFS +L+ +A + R LL PGV K+ G+ Sbjct: 131 ELPEGVLGPYFNDEFGDTFITLHSISGDGFSYPELKRFAIEGRDMLLATPGVEKVVVLGD 190 Query: 187 RNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNLRA 246 + E IYID+ + + G++ L +AI GQN V G + TG V + G + Sbjct: 191 QPEKIYIDLSSKVLAERGLTFNDLRNAIAGQNNVDYAGSVDTGTRSVRISVEGDVTKVED 250 Query: 247 LEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLGKAL 306 + E ++ +R+ RLGDIAT+T G ++P + R NG + IGV M G +V +GKA+ Sbjct: 251 IRELRLRAGDRTIRLGDIATVTSGLEDPYARKFRFNGHDSVQIGVVMAKGFNVTDVGKAV 310 Query: 307 DARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGMV 366 +A + LP G+++ VS+ P V +++ +F A+ EA+ IVL+VS +S+G R+G+V Sbjct: 311 EATYDRFESALPYGVSVDQVSNQPEVVTEAITEFSHALIEALIIVLIVSFLSIGWRSGLV 370 Query: 367 VVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNRR 426 + I+IP+VLA T MY I L ++SLG L++ALGLLVDDA+I VEMM KLE+G + Sbjct: 371 IAIAIPLVLAATFAIMYELGIDLQRISLGALIIALGLLVDDAMIVVEMMERKLEEGLEKI 430 Query: 427 RAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVVL 486 AA+FAY+STAFPMLTGTL+T AGF+P+ A+S GEY RS+F V IAL++SW AV Sbjct: 431 DAASFAYSSTAFPMLTGTLITTAGFIPVGFAESTAGEYVRSLFYVVGIALVVSWFVAVYF 490 Query: 487 IPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRGR 546 P LGY +LK++ HAG H ++ TR Y LR +V W V R Sbjct: 491 TPWLGYMILKQR------------HHAG-----THHDVFDTRFYRRLRTTVGWAVRHRVV 533 Query: 547 VVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLKD 606 V++ T +F+ SL AF +P+ FFP S RPE+L+DL LPE S + +++A +E + D Sbjct: 534 VLLMTLAIFVTSLWAFQFIPKNFFPQSSRPEILVDLWLPEGTSIKEVEKQAKALEERMMD 593 Query: 607 RPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRRQFS 666 +++G GAPRF+LPLDQQL +PNFAQ +V AK RE L L L F Sbjct: 594 DEDKRFIATYIGEGAPRFFLPLDQQLRNPNFAQLLVMAKDEPARERLIAKLRTILAEDFP 653 Query: 667 GARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWDEPAQ 726 R ++ RL GPP G+PVQ R+ G +VR IA+QV + ++ I DW EP Sbjct: 654 SIRAKVDRLFLGPPTGWPVQMRVMGPDREEVRRIADQVKTKFQENPMLGAIHDDWLEPVP 713 Query: 727 RSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSERVDPA 786 ++ IDQ RA LG++SQ+I L +SG + +R+ ++ +S+ R P R + Sbjct: 714 -AMKLVIDQDRARALGITSQRIRQMLQAAMSGVPLDSFRDGEETVSIMAREPGGNRHLLS 772 Query: 787 RLATLSMPTA-NGPVPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDVTNDV 845 + ++ +PT G VP++ + + +E G+ W R+R PTITV + GVQ DV + Sbjct: 773 AVQSVYVPTDFGGFVPVSQIAKVVPVMEQGIEWRRDRLPTITVRGTLPDGVQPNDVAMQL 832 Query: 846 NQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFGRTMM 905 +L LR L GY++++ G E++A++Q+SI+A+ P+M++ +++LLMVQLQ FG+ M+ Sbjct: 833 FDELKGLRDGLAPGYKVEIQGGAEDSAESQASIAAKAPIMLVVIVILLMVQLQHFGKAML 892 Query: 906 VVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGRF 965 V+ T PLG+IG ALL+ G PFGFVA+LG IA+LGII+RNS+ILVDQI+QDIAAG R Sbjct: 893 VLATGPLGIIGAAAALLISGAPFGFVAILGVIALLGIIIRNSIILVDQIDQDIAAGMERS 952 Query: 966 DAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPALY 1025 +AI+GA VRRFRPI LTA AVLALIP+ R F+GP+A A+MGGI +AT+LT+ LPA Y Sbjct: 953 EAIIGAAVRRFRPIILTALTAVLALIPISRGVFWGPLAYAMMGGILVATVLTILVLPAGY 1012 Query: 1026 ALCY-------RVKPDETHHRDTAAQGSH 1047 AL + + P+ +D A + H Sbjct: 1013 ALFFGKEPKSRKTDPEPLAAQDNADEQEH 1041 >mlr7298 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1046 Score = 872 bits (2254), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/1039 (43%), Positives = 661/1039 (63%), Gaps = 19/1039 (1%) Query: 7 FNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQVQ 66 FNLS W + H ++ F+ L+ + G R+ Q EDP FTF+VMV+Q WPG++ ++++ Sbjct: 11 FNLSRWAIGHPSIARFLFGLIIIAGALGLMRMGQKEDPDFTFRVMVVQAIWPGSSIQEME 70 Query: 67 EQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMAA 126 +Q+ ++I RKLQETP +DF+RS++RAG + + IK A++V +YQVRKKVGD++ Sbjct: 71 DQVVNKIERKLQETPHLDFVRSFTRAGSAIITVQIKGDTNAAEVADAFYQVRKKVGDISG 130 Query: 127 TLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFGE 186 LPQG+ GPYFNDEFGD + +++++GDGFS +L+ +A Q R LL PGV K G+ Sbjct: 131 DLPQGLLGPYFNDEFGDTFITLHSISGDGFSYPELKKFAIQARDMLLTTPGVEKAVIIGD 190 Query: 187 RNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNLRA 246 + E +YID+ + + G++ L +AI GQN V P G + TG + V + G Sbjct: 191 QPEKLYIDVSSKALAERGLTLPDLQNAIKGQNNVDPAGAVDTGVNSVRISVEGDVTKAAD 250 Query: 247 LEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLGKAL 306 + E ++ + RLGDIAT+T G ++P ++ R NG + +GV M G V +GK + Sbjct: 251 IRELRLRAGGQVTRLGDIATVTSGLEDPFQRKYRFNGHDSVQLGVVMAKGFKVTDVGKDV 310 Query: 307 DARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGMV 366 +A + + LP G+++ +S P V +V +F+ A+ EA+ IVLVVS +S+G R+G+V Sbjct: 311 EATYKRFEEALPYGVSVDQISDQPGVVTDAVAEFMHALGEALLIVLVVSFLSIGWRSGLV 370 Query: 367 VVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNRR 426 + I+IP+VLA T MY I L ++SLG L++ALGLLVDDA+I VEMM KLE+G + Sbjct: 371 IAIAIPLVLAATFAIMYELGIDLQRISLGALIIALGLLVDDAMIVVEMMERKLEEGLVKI 430 Query: 427 RAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVVL 486 AA+FAYTSTAFPML+GTL+T AGF+P+ A S GEY R++F V IAL++SW AV Sbjct: 431 EAASFAYTSTAFPMLSGTLITTAGFIPVGFAASTAGEYVRTLFYVVGIALIVSWFVAVYF 490 Query: 487 IPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRGR 546 P LG +LK++ HAG H ++ TR Y LR +V W V R Sbjct: 491 TPWLGNMILKQR------------KHAG-----THHDVFDTRFYRRLRATVGWAVRHRII 533 Query: 547 VVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLKD 606 V++ T V F SL AF +PQ FFP S RPE+L+DL LPE S + + +A +EA + D Sbjct: 534 VLVMTLVTFGTSLWAFQFIPQNFFPQSSRPEILVDLWLPEGTSIKEVETQAKALEAKMMD 593 Query: 607 RPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRRQFS 666 +++G GAPRF+LPLDQQL +PNFAQ +V A RE L L L F Sbjct: 594 DKDKRFIATYIGEGAPRFFLPLDQQLRNPNFAQMLVMANDEPARERLIVKLRTVLAEDFP 653 Query: 667 GARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWDEPAQ 726 R ++ RL GPP G+PVQ R+ G +VR IA+QV A+ R++ + DW EP Sbjct: 654 SIRAKVDRLFLGPPTGWPVQMRVMGPDRQEVRRIADQVKAKFREDPLLGAVHDDWLEPVP 713 Query: 727 RSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSERVDPA 786 ++ IDQ RA LG++SQ+I L ++G + +R+ ++ +S+ R P + R + Sbjct: 714 -AMKLVIDQDRARALGVTSQRIRQMLQATMAGAPLDDFRDGEETVSIVAREPDASRSLLS 772 Query: 787 RLATLSMPTA-NGPVPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDVTNDV 845 + ++ +PT G VPL+ + + LE G+ W R+R PTI+V A + GVQ DV + Sbjct: 773 SVDSVYVPTDFGGFVPLSQVAKVVPVLEQGIEWRRDRLPTISVRATLPDGVQSNDVVTKM 832 Query: 846 NQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFGRTMM 905 + + LR L GY+I++ G E++A++Q+SI+A+ P+M+ +++LLM+QLQ+FG+ M+ Sbjct: 833 YKDMQGLRDGLAPGYKIEIQGGAEDSAESQASIAAKAPIMLAIIVVLLMIQLQNFGKAML 892 Query: 906 VVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGRF 965 V+ T PLG+IG ALL+ G PFGFVA+LG IA+LGIIMRNS+ILVDQI+QDIA G R Sbjct: 893 VLATGPLGIIGAAAALLISGAPFGFVAILGVIALLGIIMRNSIILVDQIDQDIARGMERS 952 Query: 966 DAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPALY 1025 +AI+G+ VRRFRPI LTA AVLALIP+ R+ F+GP+A A+MGGI +AT+LT+ LPA Y Sbjct: 953 EAIIGSAVRRFRPIVLTAMTAVLALIPISRAVFWGPLAYAMMGGIVVATVLTILVLPAGY 1012 Query: 1026 ALCYRVKPDETHHRDTAAQ 1044 AL + +P + + + A + Sbjct: 1013 ALFFGREPKKVVNSEQAPE 1031 >mlr2404 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1034 Score = 865 bits (2234), Expect = 0.0, Method: Compositional matrix adjust. Identities = 450/1033 (43%), Positives = 635/1033 (61%), Gaps = 21/1033 (2%) Query: 6 RFNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQV 65 RFNLS W + ++ALV F++ + + G+ +Y RL + EDP FT + MV+Q +WPGAT Sbjct: 4 RFNLSEWAVHNRALVVFLMLICVIGGVSAYERLGRQEDPDFTVQTMVVQANWPGATTADT 63 Query: 66 QEQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMA 125 +Q+TDRI +KL+ETP++D+++SY++ GQ+ +F +K++ P + WYQVRKKV D+ Sbjct: 64 LKQVTDRIEKKLEETPNLDYIKSYTKPGQATIFVYLKESTPKRDLSDIWYQVRKKVSDIG 123 Query: 126 ATLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFG 185 TLPQGV GP+FNDEFGDV+ +Y + DGFS + RD+A+ RGE L P V K+D +G Sbjct: 124 PTLPQGVVGPFFNDEFGDVFGTVYGITYDGFSAREARDFAETARGEFLRAPDVGKVDIYG 183 Query: 186 ERNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNLR 245 +++E +Y++ ++ L ++ + AI QNAV P G+I T + + V TG + Sbjct: 184 DQDEKVYLNFSPQKLANLKLNLDDVLAAIARQNAVAPSGIINTPQENMLVDVTGSLLSSD 243 Query: 246 ALEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLGKA 305 + + I+ R ++L DIA + RGY +P + R NG+P +GIGV M+ GG+ + GK Sbjct: 244 GIANLNLWIDGRFYKLTDIAQVQRGYSDPPSKMFRINGKPAIGIGVNMREGGNNLDFGKG 303 Query: 306 LDARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGM 365 L E L++R P G+ L VS P V +++ F EA+ EA+ IVLVVS +SLG R G+ Sbjct: 304 LHEAAERLKQRFPVGIELNLVSDQPEVVHEAIGGFTEALVEAIVIVLVVSFLSLGFRAGL 363 Query: 366 VVVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNR 425 VV +SIP+VLA+ + M I L ++SLG L++ALGLLVDDA+I +EMM K+E+G + Sbjct: 364 VVALSIPLVLAIVFVAMDALGISLQRISLGALIIALGLLVDDAMITIEMMISKIEEGMEK 423 Query: 426 RRAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVV 485 +AA FAYTSTAFPMLTGTL+T+ GFLPI A S TG+Y S+F V A+AL+ SW AVV Sbjct: 424 IKAATFAYTSTAFPMLTGTLITILGFLPIGFANSNTGQYCFSLFVVIAVALVASWFVAVV 483 Query: 486 LIPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRG 545 P++G +L P Q A P R R + + + R Sbjct: 484 FAPVIGLSIL---PSHTKKAQANAEPG---------------RFMRAFERLLGFAMRHRW 525 Query: 546 RVVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLK 605 + A +LF SL V QQFFP+S+RPELL+ + LP+ AS ATQ + R+E L Sbjct: 526 PTIAAALILFSASLYGMGFVQQQFFPTSNRPELLVTMTLPKNASIAATQAQTERLEKALA 585 Query: 606 DRPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRRQF 665 P I + S+VG GA RFYLPLD QL + A+ VV K ++ R+ + LE F Sbjct: 586 GDPDIARFSSYVGGGAIRFYLPLDVQLDNDFMAETVVVTKDLKARDRVQARLETLFAGSF 645 Query: 666 SGARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWDEPA 725 R++RLE GPPVG+PVQ+R+S + R AEQVA +R N+ +DW E Sbjct: 646 PDVAVRISRLELGPPVGWPVQYRVSAPTTEEARQYAEQVAQTLRASGLVRNVNYDWAE-K 704 Query: 726 QRSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSERVDP 785 +++ +DQ R Q GLSS++++ L +SG T+TQ R+ L+ V RA ER Sbjct: 705 NKALRIVVDQDRVRQAGLSSEELAQALNRVISGSTVTQIRDSIYLVDVVARAESDERSSV 764 Query: 786 ARLATLSMPTANG-PVPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDVTND 844 L L + T G VPL L QF L+ G +W R R PTITV A+ PG+Q V Sbjct: 765 EALRNLQITTPTGASVPLRELAQFQYDLDDGYVWRRGRLPTITVQAEPLPGLQPASVHGR 824 Query: 845 VNQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFGRTM 904 + + LR +P G ++ GG VE++A++ +++ AQ PLM+ +L +LMVQL SF + Sbjct: 825 IAGAIEGLRKSMPAGTLLETGGTVEKSAQSNAALLAQFPLMITLMLTVLMVQLGSFRQLA 884 Query: 905 MVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGR 964 MV+ APLGLIGV ALL P GF+A LG IA+ G+I+RNSVILV QIE + A G Sbjct: 885 MVISVAPLGLIGVAAALLTTNTPMGFIATLGIIALAGMIIRNSVILVHQIEHERAQGIEP 944 Query: 965 FDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPAL 1024 + A++ AT RFRPI LTAAAA+L +IP++ F+GPMA A++GG+ +AT+LTL +LPAL Sbjct: 945 WKAVIDATTHRFRPIMLTAAAAILGMIPIMHDVFWGPMAFAIVGGLAVATVLTLVFLPAL 1004 Query: 1025 YALCYRVK-PDET 1036 Y ++ DET Sbjct: 1005 YVAVNGIREKDET 1017 >mll5518 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1018 Score = 862 bits (2226), Expect = 0.0, Method: Compositional matrix adjust. Identities = 468/1031 (45%), Positives = 648/1031 (62%), Gaps = 28/1031 (2%) Query: 7 FNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQVQ 66 FNLS W L H+++V + + + + GI SY L + EDP FT K M+IQ +WPGA+ ++ Sbjct: 4 FNLSDWALSHRSMVWYFMLVFVVAGIFSYLNLGREEDPNFTIKTMIIQANWPGASVKETL 63 Query: 67 EQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMAA 126 +Q+TDRI +KL+E +DF RS + AGQ+ +F +KDT A V W QVR V D+ A Sbjct: 64 QQVTDRIEKKLEELDSLDFTRSVTTAGQTVIFVNLKDTTRARDVVPNWLQVRNMVNDIKA 123 Query: 127 TLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFGE 186 PQGV+GP+FND FGDVY NIYA DG +P QLRDY + R ++L VP K+D G Sbjct: 124 QFPQGVQGPFFNDRFGDVYGNIYAFTSDGLTPRQLRDYVEDARTKILTVPNAGKVDLVGA 183 Query: 187 RNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQF---DN 243 ++E IY++ ++ LG++ Q + ++ QNA+ P G+I +G +R+ VR GQF D+ Sbjct: 184 QDEAIYLEFSTRQIAALGLNQQAIVASLQAQNAITPSGVIQSGPERISVRVGGQFTSEDS 243 Query: 244 LRALEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLG 303 LRA+ +++N+R FRL D+ATITRGY +P R NGQ + + + M+P ++++ G Sbjct: 244 LRAIN---LRVNDRFFRLSDVATITRGYADPPTALFRFNGQDAIALAIGMKPNANLLQFG 300 Query: 304 KALDARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRT 363 +AL ++ LP G+ + V+ P VE++V F A+ EAVAIVL VS +SLG+R Sbjct: 301 EALHKEMNKVLADLPVGVGVHLVADQPVIVEEAVSGFTRALFEAVAIVLAVSFISLGMRA 360 Query: 364 GMVVVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGW 423 G VV +SIP+VLA+T M I L ++SLG L++ALGLLVDDA+IAVEMM +LE G Sbjct: 361 GFVVALSIPLVLAITFTVMAYLGISLQRISLGALIIALGLLVDDAMIAVEMMVARLEVGD 420 Query: 424 NRRRAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAA 483 N R+AA + YTSTAFPMLTGTLVTVAGF+PI L S GEYT ++F V A++LL+SW+ A Sbjct: 421 NLRKAATYVYTSTAFPMLTGTLVTVAGFIPIGLNSSAAGEYTFTLFVVIAVSLLVSWIVA 480 Query: 484 VVLIPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAF 543 V+ PLLG +L A + HD P R+ + RR + V Sbjct: 481 VLFAPLLGVTILP----------------ATMKTKHHDQP---GRLTSLFRRVLVGSVRH 521 Query: 544 RGRVVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEA- 602 +IAT +LF S+A F LV QQFFP SDRPEL++D +LP+ +S T+ + R E Sbjct: 522 HWLTIIATVLLFAASIAGFGLVQQQFFPPSDRPELIVDWNLPQNSSIAETRDQMERFEQR 581 Query: 603 LLKDRPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLR 662 L P IDH+ S++G GA RF L D Q A+P F Q V+ KS+E R + ALE+ LR Sbjct: 582 ALVGNPDIDHFSSYIGQGAVRFVLAYDVQPANPYFGQTVIVTKSLEARNRVKPALEKLLR 641 Query: 663 RQFSGARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWD 722 +F G + LE GPPVG PVQ+R+ G I VR +A+Q A + +R FDW+ Sbjct: 642 EEFVGTDAFVKLLELGPPVGRPVQYRVGGPDIQTVRELAQQFAGVISANARLAAPTFDWN 701 Query: 723 EPAQRSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSER 782 EP QR + ++ Q +A QLG++S I++ L + G TITQ R+ LI+V R+ +ER Sbjct: 702 EP-QRVLRVDVLQDKARQLGITSSDIASALNSTVGGATITQVRDATYLINVVARSRDAER 760 Query: 783 VDPARLATLSMPTANG-PVPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDV 841 L L +PT+ G +PLA + F LE +W R+R PTITV A + Sbjct: 761 GSIGTLQNLQLPTSTGEAIPLAAVANFRYELEQPTVWRRDRIPTITVRAGLVGDTLPATA 820 Query: 842 TNDVNQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFG 901 N++ ++A A+LP Y ++ G VEE+AK+Q I+A +PLM+ + +LM+QLQSF Sbjct: 821 VNELKPSVDAFIAKLPPRYSVETAGSVEESAKSQGPIAAVVPLMLFVMATILMIQLQSFQ 880 Query: 902 RTMMVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAG 961 R +VV APLGLIGVV AL+ G P GFVA+LG +A++GI++RNSVIL+ QIE + G Sbjct: 881 RLFLVVAVAPLGLIGVVAALVPSGAPLGFVAILGVLALIGILIRNSVILIVQIEDLVREG 940 Query: 962 RGRFDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYL 1021 + R+ A++ AT R RPI LTAAAA LALIP+ R F+GPMA A+MGGI T +TL +L Sbjct: 941 KDRWAAVIEATEHRMRPIALTAAAASLALIPIAREVFWGPMAYAMMGGIIAGTAITLLFL 1000 Query: 1022 PALYALCYRVK 1032 PALY +R+K Sbjct: 1001 PALYVTWFRIK 1011 >AGpA548 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1052 Score = 859 bits (2219), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/1043 (43%), Positives = 660/1043 (63%), Gaps = 20/1043 (1%) Query: 6 RFNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQV 65 +FNLS W + H ++ F+ L+ ++G + Q EDP FTF+VMV+Q+ WPGA+ + Sbjct: 15 KFNLSRWAISHPSIARFLFGLIIVMGALGVINMGQKEDPDFTFRVMVVQSVWPGASIDDM 74 Query: 66 QEQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMA 125 Q Q+ ++I RKLQETP +D+++SY RAG + IK + V +YQVRKKVGD+ Sbjct: 75 QNQVVNKIERKLQETPHLDWVKSYIRAGVAITTIQIKGDTNGADVADAFYQVRKKVGDIK 134 Query: 126 ATLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFG 185 LP G+ GPYFNDEFGD Y ++A++GDG+S +L+ +A Q R L+ +PGV K G Sbjct: 135 QDLPSGLLGPYFNDEFGDTYITLHAISGDGYSYPELKKFAIQARDMLIAMPGVEKAVILG 194 Query: 186 ERNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNLR 245 ++ + I+ID+ + + G++ + +A+ GQN V P G + T + V + G Sbjct: 195 DQPQKIFIDVSSKALAERGLTVVDIQNALQGQNDVDPAGSVETADRSVRISVEGDVTTPA 254 Query: 246 ALEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLGKA 305 + E ++ ++ RLGDIAT+ G ++P ++ R NG + +GV M G V +GK Sbjct: 255 EIRELRLKAGDQVIRLGDIATVRDGLEDPFQRKFRVNGHDTVELGVVMAKGFKVTDVGKG 314 Query: 306 LDARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGM 365 ++ + LP G+ +T +S+ P V ++V +F +A+ EA+ IVL+VSL+S+G R+G+ Sbjct: 315 IEETYKRFEDTLPVGVEVTQISNQPEVVTEAVGEFTQALMEALGIVLIVSLISIGWRSGI 374 Query: 366 VVVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNR 425 V+ ++IP+VLA T M+ I L ++SLG L++ALGLLVDDA+I VEMM KLE+G NR Sbjct: 375 VIAVAIPLVLAATLAIMFYMGIELQRISLGALIIALGLLVDDAMIVVEMMERKLEEGLNR 434 Query: 426 RRAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVV 485 AA+FAY+STAFPMLTGTL+T AGF+P+ A S GEY RS+F V IAL+ SW AV Sbjct: 435 LDAASFAYSSTAFPMLTGTLITTAGFIPVGFAASTAGEYVRSLFFVVGIALVTSWFVAVY 494 Query: 486 LIPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRG 545 P LGY +LK++ HAG H Y TR Y + +V W V + Sbjct: 495 FTPWLGYMILKQR------------AHAG-----THHDAYDTRFYRGVGHTVGWAVRHKA 537 Query: 546 RVVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALLK 605 V++ T F+GSL +F +PQ FFP S RPE+L+D+ LPE + + +R+A +EA + Sbjct: 538 IVLLLTLGAFVGSLWSFQFIPQSFFPQSSRPEILVDMWLPEGTAIKEVERQAKALEAKIM 597 Query: 606 DRPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRRQF 665 D P +F+G GAPRF+LPLDQQL +PN+AQ +V + +E+RE + L + L F Sbjct: 598 DDPDKKFVATFIGEGAPRFFLPLDQQLRNPNYAQLLVMSNGLEERERMIVKLRKILAEDF 657 Query: 666 SGARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWDEPA 725 R ++ RL GPPVG+ VQ R+ G +VR+IA+QV ++ + DW EP Sbjct: 658 PTVRGKVDRLFLGPPVGWAVQMRVVGPDRAEVRSIADQVKQRFEQQPNFGAVHDDWMEPV 717 Query: 726 QRSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSERVDP 785 ++ IDQ RA LG+SSQ++ L +G I+ +R+ ++ +S+ +R P + R Sbjct: 718 P-AMKLVIDQDRARALGVSSQRVRQILQAATNGAAISDFRDGEETVSIVVREPDATRSLL 776 Query: 786 ARLATLSMPT-ANGPVPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDVTND 844 + + ++ +PT G VP + + + LE G+ W R+R PTITV A + GV+ VT + Sbjct: 777 SAVNSVYIPTDIGGFVPASQIARVVPLLEQGIEWRRDRLPTITVKATLPDGVEPTQVTMN 836 Query: 845 VNQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFGRTM 904 + + LRA+LP GY++++ G E+ A++Q SI+A+ P+M++ +L+LLM+QLQ FG+ M Sbjct: 837 LYNSMADLRAKLPAGYKVEIQGGAEDAAESQQSIAAKAPIMLLVILVLLMIQLQHFGKAM 896 Query: 905 MVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGR 964 +V+ T PLG+IG ALL+ G PFGFVA+LG IA+LGIIMRNS+ILVDQI+QDIAAG R Sbjct: 897 LVLATGPLGIIGAAMALLITGAPFGFVAILGVIALLGIIMRNSIILVDQIDQDIAAGHPR 956 Query: 965 FDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPAL 1024 +AIVGA VRRFRPI LTA AVLALIP+ R F+GPMA A+MGGI +AT+LT+ LPA Sbjct: 957 AEAIVGAAVRRFRPIMLTALTAVLALIPISRGLFWGPMAYAMMGGILVATVLTILVLPAA 1016 Query: 1025 YALCYRVKPDETHHRDT-AAQGS 1046 YAL + +P + A+QG Sbjct: 1017 YALFFGREPKAKKEDEKPASQGE 1039 >PA0158 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1015 Score = 850 bits (2196), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/1028 (44%), Positives = 654/1028 (63%), Gaps = 21/1028 (2%) Query: 5 GRFNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQ 64 G FNLS W L+HQ+LV +++A+ ++G+ SY L + EDP F K MVIQT WPGAT Sbjct: 3 GGFNLSDWALRHQSLVWYLMAVSLVMGVFSYLNLGREEDPSFAIKTMVIQTRWPGATVDD 62 Query: 65 VQEQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDM 124 EQ+TDRI +KL+E +D+++SY+R G+S +F +KDT A +P WYQVRKK+ D+ Sbjct: 63 TLEQVTDRIEKKLEELDSLDYVKSYTRPGESTVFVYLKDTTKAGDIPDIWYQVRKKISDI 122 Query: 125 AATLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYF 184 PQG++GP FNDEFGDV+ ++YA DG QLRDY +++R ++ V + K+ Sbjct: 123 QGEFPQGIQGPGFNDEFGDVFGSVYAFTADGLDFRQLRDYVEKVRLDIRSVKDLGKVQMI 182 Query: 185 GERNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNL 244 G +NE IY++ ++ LG+ +Q+ ++ QNAV P G++ G +R+ VR +G F + Sbjct: 183 GAQNEVIYLNFSTRKLAALGLDQRQVVQSLQAQNAVTPSGVVEAGPERISVRTSGNFRSE 242 Query: 245 RALEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLGK 304 + L+ +++N+R +RL D+A+I+R + +P R G+P +G+ V M+ GG+++ G+ Sbjct: 243 KDLQAVNLRVNDRFYRLSDLASISRDFVDPPTSLFRYKGEPAIGLAVAMKEGGNILEFGE 302 Query: 305 ALDARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTG 364 AL+AR +E+ LP G+ + VS+ V+K+V F A+ EAV IVL+VS VSLG+R G Sbjct: 303 ALNARMQEITGELPVGVGVHQVSNQAQVVKKAVGGFTRALFEAVVIVLIVSFVSLGLRAG 362 Query: 365 MVVVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWN 424 +VV SIP+VLA+ +FM DI + +VSLG L++ALGLLVDDA+I VEMM +LE G + Sbjct: 363 LVVACSIPLVLAMVFVFMEYTDITMQRVSLGALIIALGLLVDDAMITVEMMITRLELGDS 422 Query: 425 RRRAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAV 484 +A +AYTSTAFPMLTGTLVTVAGF+PI L S GEYT ++F V A+ALLLSW+ AV Sbjct: 423 LHDSATYAYTSTAFPMLTGTLVTVAGFVPIGLNASSAGEYTFTLFAVIAVALLLSWIVAV 482 Query: 485 VLIPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFR 544 + P++ H+L P L H ++ + + ++ +RR W F Sbjct: 483 LFAPVIAVHIL---PKTLK--------HKSEQKKGRIAERFDSLLHLAMRRR--WTTIF- 528 Query: 545 GRVVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRMEALL 604 T +LF SL V QFFPSSDRPELL+DL+LP+ +S T+ R+EA L Sbjct: 529 -----LTALLFGVSLFLMKFVQHQFFPSSDRPELLVDLNLPQNSSIHETRAVMDRLEATL 583 Query: 605 KDRPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRRQ 664 KD IDH+ ++VG GA RFYLPLDQQL + + Q V+ K +E RE +A L + LR+ Sbjct: 584 KDDEDIDHWSAYVGEGAIRFYLPLDQQLQNNFYGQLVIVTKDLEARERVAARLRDRLRKD 643 Query: 665 FSGARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWDEP 724 + G T + LE GPPVG P+Q+R+SG QI KVR A +A + +I +DW+EP Sbjct: 644 YVGISTYVQPLEMGPPVGRPIQYRVSGPQIDKVREYAMGLAGVLDGNPNIGDIVYDWNEP 703 Query: 725 AQRSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSERVD 784 + + +I Q +A QLGLSS+ ++ + ++G +TQ R+ L++V RA SER Sbjct: 704 G-KMLKIDIAQDKARQLGLSSEDVAQIMNSVVTGSAVTQVRDDIYLVNVIGRAEDSERGS 762 Query: 785 PARLATLSMPTANG-PVPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDVTN 843 L +L + T +G +PL + + LE ++W R+R+PTITV A +R +Q D+ Sbjct: 763 LETLESLQIVTPSGTSIPLKAFAKVSYELEQPLVWRRDRKPTITVKASLRGEIQPTDLVA 822 Query: 844 DVNQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFGRT 903 + ++ LP YRI+VGG VEE+ KA+ I+ +PLM+ + LM+QLQS + Sbjct: 823 RLAPEVKRFADGLPANYRIEVGGTVEESGKAEGPIAKVVPLMLFLMATFLMIQLQSVQKL 882 Query: 904 MMVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRG 963 +V APLGLIGVV ALL G P GFVA+LG +A++GII+RNSVILV QI+ G+ Sbjct: 883 FLVASVAPLGLIGVVAALLPTGTPMGFVAILGILALIGIIIRNSVILVTQIDAFEKDGKT 942 Query: 964 RFDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPA 1023 ++A++ AT R RPI LTAAAA L +IP+ R F+GPMA A++GGI AT+LTL +LPA Sbjct: 943 PWEAVLEATHHRTRPILLTAAAASLGMIPIAREVFWGPMAYAMIGGIVAATLLTLIFLPA 1002 Query: 1024 LYALCYRV 1031 LY YR+ Sbjct: 1003 LYVAWYRI 1010 >BMEII0382 [V] COG0841 Cation/multidrug efflux pump Bme Brucella melitensis Length = 1024 Score = 848 bits (2191), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/1038 (44%), Positives = 645/1038 (62%), Gaps = 28/1038 (2%) Query: 7 FNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQVQ 66 FNLS W L H++LV + + + + G+ SY L + EDP FT K MV+Q +WPGA+ + Sbjct: 5 FNLSDWALNHRSLVWYFMLVFLVAGLVSYLDLGREEDPEFTVKTMVVQANWPGASIDETL 64 Query: 67 EQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMAA 126 Q+TDR+ +KL+E +D+ RS + AG+S +F +KDT A V ++W +V + D+ Sbjct: 65 NQVTDRLEKKLEELDTLDYTRSVTTAGKSVVFVFLKDTTRAQDVKKSWTEVCHLLTDIQN 124 Query: 127 TLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFGE 186 TLPQGV GPYFND+FGDV+ NIYA DG S QLRDYA+ +R ++L +P K++ G Sbjct: 125 TLPQGVYGPYFNDQFGDVFGNIYAFTADGLSMRQLRDYAEDVRTKILTIPNAGKVELIGA 184 Query: 187 RNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNLRA 246 ++E IY++ ++ LG+ Q + A+ QNA+ P G++ G +R+ VR +GQF++ Sbjct: 185 QDEAIYLEFSTRQVAALGLDQQAILKALQDQNAITPSGVVQAGPERISVRVSGQFNSEAD 244 Query: 247 LEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLGKAL 306 L +++NNR FRL D+ATITRGY +P R NG+ +G+G+ M+P G+++ G L Sbjct: 245 LRAVNLRVNNRFFRLSDVATITRGYVDPPTSIFRVNGEDAIGLGIGMKPNGNLLEFGAEL 304 Query: 307 DARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGMV 366 D +++ LP G+ + V+ P V+++V F +A+ EAV IVL VS VSLG+R G V Sbjct: 305 DKMMDQVTAELPVGVKVFKVADQPQVVKEAVSGFTQALFEAVVIVLAVSFVSLGLRAGFV 364 Query: 367 VVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNRR 426 V +SIP+VLA+T L M L DI L +VSLG L++ALGLLVDDA+IAVEMM +LE G Sbjct: 365 VSLSIPLVLAITFLSMSLMDISLQRVSLGALIIALGLLVDDAMIAVEMMVARLEHGDPIN 424 Query: 427 RAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVVL 486 +AA + Y+ TAFPMLTGTLVT+AGF+PI L S GEYT ++F V A++LL+SW+ AV+ Sbjct: 425 KAATYVYSHTAFPMLTGTLVTIAGFIPIGLNNSQAGEYTFTLFVVIAVSLLVSWVVAVLF 484 Query: 487 IPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLRRSVAWCVAFRGR 546 PLLG L +K PH EE ++R + R + + + Sbjct: 485 APLLGVTFLPKK----------MKPH----EEK------RSRFFEAFSRVLLLSMRHKWT 524 Query: 547 VVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRM-EALLK 605 +I T VLF+ S+ + +QFFP SDRPEL++D LP+ +S T+ + R E +LK Sbjct: 525 TIITTIVLFVISVFGMGFIERQFFPQSDRPELVLDWTLPQNSSIADTKAQMERFEETMLK 584 Query: 606 DRPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRRQF 665 D P ++H+ ++VG GA RF L D Q A+P F Q VV A+ VE R+ L E R+ + Sbjct: 585 DNPDVEHWSTYVGQGAIRFVLSFDVQPANPYFGQMVVVARDVEARDRLKAKFEAAFRKDY 644 Query: 666 SGARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWDEPA 725 G + LE GPPVG PVQ+RISG + K+R IA+ A + + R + ++W+EP Sbjct: 645 VGTDVYVKYLELGPPVGRPVQYRISGPDVQKLRGIAQDFAGILSADKRLGVVNYNWNEPG 704 Query: 726 QRSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSERVDP 785 R + ++ Q +A +LG+SS+ I+ L + G TITQ R+ LI V RA ER Sbjct: 705 -RVIRVDVMQDKARKLGISSKDIATTLNGVVGGITITQVRDSIYLIDVIARAQAHERDSI 763 Query: 786 ARLATLSMPTANG-PVPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDVTND 844 L +L + T NG VPLA + F LE VI+ R+R PTITV A + + D Sbjct: 764 DTLQSLQIATGNGTSVPLAAIANFRYELEQPVIYRRSRIPTITVAAGIIDKTMPDTIARD 823 Query: 845 VNQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFGRTM 904 + + LP GY I G VEE+ K+Q I+A +PLM+ + +LMVQLQSF R Sbjct: 824 LGPAIKTFADRLPAGYYIQTAGTVEESGKSQGPIAAVVPLMLFVMATVLMVQLQSFQRLF 883 Query: 905 MVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGRGR 964 +VV APLGLIGVV ALL G+P GFVA+LG +A++GI++RNSVIL+ Q+E+DI G Sbjct: 884 LVVAVAPLGLIGVVAALLPSGKPLGFVAILGVLALIGILIRNSVILIVQVEEDIQEGLHP 943 Query: 965 FDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLPAL 1024 +DA++ A+ R RPI LTAAAA LALIP+ R F+GPMA A+MGGI T +TL +LPAL Sbjct: 944 WDAVMKASQHRMRPIALTAAAASLALIPIAREVFWGPMAYAMMGGIIAGTAITLLFLPAL 1003 Query: 1025 YALCYRVK-----PDETH 1037 Y +R+K PDE H Sbjct: 1004 YVAWFRIKEPEHSPDEPH 1021 >AGl2075 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1023 Score = 822 bits (2124), Expect = 0.0, Method: Compositional matrix adjust. Identities = 450/1043 (43%), Positives = 640/1043 (61%), Gaps = 27/1043 (2%) Query: 6 RFNLSAWTLQHQALVTFILALVTLLGIGSYSRLSQSEDPPFTFKVMVIQTDWPGATARQV 65 +FNLS W L+H++LV + + + L G+ SY L + EDP FT K MVI WPGA+A +V Sbjct: 3 KFNLSDWALEHRSLVWYFMLVFVLAGVFSYLNLGREEDPNFTIKTMVISAQWPGASAEEV 62 Query: 66 QEQITDRIARKLQETPDVDFLRSYSRAGQSQLFFTIKDTAPASQVPQTWYQVRKKVGDMA 125 Q+TDRI +KL+E ++D LRS + AG++ +F + A V TW +VR +GD+ Sbjct: 63 ARQVTDRIEKKLEELDNLDHLRSQTVAGRTTIFVELVPETKARNVEPTWVRVRNMIGDIK 122 Query: 126 ATLPQGVKGPYFNDEFGDVYTNIYALAGDGFSPAQLRDYADQLRGELLHVPGVAKIDYFG 185 P GV GP+FND FGDVY NIYA DG S QLRD + R ++L V + K+D G Sbjct: 123 GEFPSGVVGPFFNDRFGDVYGNIYAFTSDGLSQRQLRDLVEDARAKVLTVDDIGKVDVIG 182 Query: 186 ERNEHIYIDIGNARMTRLGISPQQLADAIGGQNAVVPGGLITTGNDRVYVRPTGQFDNLR 245 ++E IY++ ++ LGI Q + + QNAV G + G +RV +R +GQF + Sbjct: 183 AQDEAIYLEFSTRQIAALGIDQQSIIKTLQSQNAVTQSGFVNAGPERVALRVSGQFTSED 242 Query: 246 ALEEKIIQINNRSFRLGDIATITRGYDEPQEQAMRTNGQPVLGIGVTMQPGGDVIRLGKA 305 +L +++NNR F L ++ATI RGY +P R NGQP +G+ + M+ G +++ G+A Sbjct: 243 SLRSINLRVNNRFFPLTEVATIRRGYVDPPSSLFRFNGQPAIGLAIGMKTGANLLHFGEA 302 Query: 306 LDARTEELRKRLPAGLTLTAVSSMPHAVEKSVDDFLEAVAEAVAIVLVVSLVSLGIRTGM 365 LDA+ + + LP G+ + VS P V+++V F A+ EA+AIVLV+S +SLG+R GM Sbjct: 303 LDAQMKRVVADLPVGVDVHRVSDQPAVVDEAVSGFTSALFEAIAIVLVISFISLGLRAGM 362 Query: 366 VVVISIPIVLAVTSLFMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMAVKLEQGWNR 425 VV +SIP+VLA+T ++M I L ++SLG L++ALGLLVDDA+IAVEMM +LE G + Sbjct: 363 VVAVSIPLVLAITFVYMEYTGISLQRISLGALIIALGLLVDDAMIAVEMMVARLEVGDDL 422 Query: 426 RRAAAFAYTSTAFPMLTGTLVTVAGFLPIALAKSGTGEYTRSIFEVSAIALLLSWLAAVV 485 R+AA + YTSTAFPMLTGTLVTVAGF+P+ L S GE+T ++F V A++L++SW+ AV+ Sbjct: 423 RKAATYVYTSTAFPMLTGTLVTVAGFIPVGLNNSAAGEFTFTLFVVIAVSLIVSWIVAVL 482 Query: 486 LIPLLGYHMLKEKPGALTDEQIAANPHAGHDEEDHDHPIYQTRIYTWLR-RSVAWCVAFR 544 PLLG +L P + + H+ ++WL R++ W R Sbjct: 483 FTPLLGVTIL---PKTM--------------KSHHEKKGRFASGFSWLLGRALRW----R 521 Query: 545 GRVVIATTVLFIGSLAAFALVPQQFFPSSDRPELLIDLHLPERASFEATQREAVRME-AL 603 ++AT LF S+ +LV QQFFPSSDR EL++D +LP+ +S T R+ + E + Sbjct: 522 WVTIVATVALFALSIGGMSLVQQQFFPSSDRVELIVDWNLPQNSSIAETNRQMAQFEQEM 581 Query: 604 LKDRPQIDHYVSFVGVGAPRFYLPLDQQLASPNFAQFVVTAKSVEDREALARALEEPLRR 663 L IDH+ ++VG GAPRF L D Q F Q V+ K ++ R+ + L++ L R Sbjct: 582 LAKNTDIDHWTTYVGEGAPRFILSFDVQTPDVTFGQTVIVTKGLDVRDKVRAELQDYLDR 641 Query: 664 QFSGARTRLTRLENGPPVGFPVQFRISGEQIPKVRAIAEQVAAEMRKESRATNIQFDWDE 723 F G + L+ GPPVG PVQ+R+SG I KVR + +Q++ + + +N+ DW+E Sbjct: 642 TFIGTDAFVKLLDIGPPVGKPVQYRLSGPDIQKVRELGQQLSGIVGEHRLLSNLVMDWNE 701 Query: 724 PAQRSVSFEIDQKRAAQLGLSSQQISNFLAMQLSGYTITQYRERDKLISVDLRAPRSERV 783 P R V ++ Q +A QLG+SS+ I+N + + G T+TQ R+ L++V RA +ER Sbjct: 702 PT-RVVKVDVLQDKARQLGVSSEDIANAMNSIVEGSTVTQVRDDIYLVNVVARAQLAERG 760 Query: 784 DPARLATLSMPTANGP-VPLATLGQFNNTLEYGVIWERNRQPTITVLADVRPGVQGIDVT 842 L L +P NG VPL+ + F LE IW R+R PT+TV A + Q + Sbjct: 761 SIETLQNLQLPATNGKAVPLSAIANFRYELEQPTIWRRDRIPTVTVKAAIIGPTQPATIV 820 Query: 843 NDVNQKLNALRAELPVGYRIDVGGPVEENAKAQSSISAQMPLMVIAVLLLLMVQLQSFGR 902 + KL A LPVGY+++ GG VE +A +Q+ I A +PLM+ A+ +LMVQLQSF R Sbjct: 821 EQLKPKLEAFEKMLPVGYKLETGGSVESSADSQAPIVAVVPLMLFAMATILMVQLQSFSR 880 Query: 903 TMMVVMTAPLGLIGVVGALLLFGQPFGFVAMLGTIAMLGIIMRNSVILVDQIEQDIAAGR 962 +V AP LIGVV ALL P GFVA+LG +A++GI++RNSVILV QIE + G Sbjct: 881 LFLVFAVAPTALIGVVVALLFSNAPMGFVAILGVLALIGILIRNSVILVVQIEHLRSEGV 940 Query: 963 GRFDAIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITIATILTLFYLP 1022 + A++ AT R RPI LTAAAA LALIP+ R F+GPMA A+MGGI + T LTL +LP Sbjct: 941 SAWRAVIEATEHRMRPIMLTAAAATLALIPISREIFWGPMAYAMMGGIVVGTALTLLFLP 1000 Query: 1023 ALYALCYRV--KPDETHHRDTAA 1043 ALY +R+ + D+ D A Sbjct: 1001 ALYVAWFRIPREDDKPEGHDVTA 1023