BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0202.p (250 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO3986 [I] COG2134 CDP-diacylglycerol pyrophosphatase Ype Yersi... 178 1e-44 jhp0805 Non COG 153 4e-37 HP0871 [I] COG2134 CDP-diacylglycerol pyrophosphatase Hpy Helico... 146 5e-35 ECs4843 [I] COG2134 CDP-diacylglycerol pyrophosphatase Ecs Esche... 145 6e-35 Zcdh [I] COG2134 CDP-diacylglycerol pyrophosphatase EcZ Escheric... 145 8e-35 cdh [I] COG2134 CDP-diacylglycerol pyrophosphatase Eco Escherich... 144 2e-34 STM4064 [I] COG2134 CDP-diacylglycerol pyrophosphatase Sty Salmo... 143 4e-34 Rv2289 [I] COG2134 CDP-diacylglycerol pyrophosphatase Mtu Mycoba... 94 3e-19 MT2346 [I] COG2134 CDP-diacylglycerol pyrophosphatase MtC Mycoba... 94 3e-19 ML1417 [I] COG2134 CDP-diacylglycerol pyrophosphatase Mle Mycoba... 92 8e-19 >YPO3986 [I] COG2134 CDP-diacylglycerol pyrophosphatase Ype Yersinia pestis Length = 258 Score = 178 bits (451), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 94/219 (42%), Positives = 125/219 (57%), Gaps = 6/219 (2%) Query: 33 LWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPTRRLTGIESPELL 92 LW+I SQQC+PHM P+PCA V++ GF +LKD GP QYLL+PT ++GIESP+LL Sbjct: 36 LWKIISQQCIPHMTTEDDPRPCAEVNIPAGFAVLKDRNGPLQYLLIPTVPISGIESPQLL 95 Query: 93 EPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHLHIDCMRRDVAAS 152 +PNY+A AWQ R +A+ G + D + + +NS GR+Q LH+HI C++ V + Sbjct: 96 TATSPNYFADAWQARYFMAEKYGAPIDDTDISLAINSQYGRTQDQLHIHISCLKPQVKTA 155 Query: 153 LAAHRDDPLQQWRPW--HFEGHRYWVMRLPAEALAQHDPFKLAAARSAYAAANMASQSLL 210 LAAH D QQW+P GH YWV R+ A L Q PF L A A M L Sbjct: 156 LAAHSADFQQQWQPLPGGLLGHDYWVRRITATELQQPGPFHLLADEMPGAKEQMGRYGLA 215 Query: 211 LTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDCR 249 +T D F L+ + Q++ SAE L DH C+ Sbjct: 216 ITALPSGD----FLLLANKASLITQDRASAEELQDHTCQ 250 >jhp0805 Non COG Length = 244 Score = 153 bits (386), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 78/224 (34%), Positives = 117/224 (52%), Gaps = 6/224 (2%) Query: 27 AADPHKLWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPTRRLTGI 86 A DP+ L +I ++C+P+ + + P PC V G+V+LKD+ GP QYLLMPT ++GI Sbjct: 21 AKDPNVLRKIVFEKCLPNYEKNQNPSPCIEVKPDAGYVVLKDINGPLQYLLMPTTHISGI 80 Query: 87 ESPELLEPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHLHIDCMR 146 E+P LL+P PN++ +WQ R +++ G+ + D + + +NS GRSQ H H+HI C+ Sbjct: 81 ENPLLLDPSTPNFFYLSWQARDFMSKKYGKPIPDYAISLTINSKKGRSQNHFHIHISCIS 140 Query: 147 RDVAASLAAHRDDPLQQWRPWH--FEGHRYWVMRLPAEALAQHDPFKLAAARSAYAAANM 204 DV L + + +W P GH+Y R+ LAQ PF + A A M Sbjct: 141 LDVRKQLDNNLKNINSRWSPLSGGLNGHKYLARRVTESELAQKSPFVMLAKEVPNAHKRM 200 Query: 205 ASQSLLLTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 L A + F L+ N + SAE + DH+C Sbjct: 201 GDYGL----AVVQQSDNSFVLLATQFNPLTLNRASAEEIQDHEC 240 >HP0871 [I] COG2134 CDP-diacylglycerol pyrophosphatase Hpy Helicobacter pylori 26695 Length = 244 Score = 146 bits (368), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 75/224 (33%), Positives = 114/224 (50%), Gaps = 6/224 (2%) Query: 27 AADPHKLWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPTRRLTGI 86 A DP+ L +I ++C+P+ + + P PC V G+V+LKD+ GP QYLLMPT ++GI Sbjct: 21 AKDPNVLRKIVFEKCLPNYEKNQNPSPCIEVKPDAGYVVLKDINGPLQYLLMPTTHISGI 80 Query: 87 ESPELLEPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHLHIDCMR 146 ESP LL+P PN++ +WQ R +++ G+ + D + + +NS+ GRSQ H H+HI C+ Sbjct: 81 ESPLLLDPSTPNFFYLSWQARDFMSKKYGQPIPDYAISLTINSSKGRSQNHFHIHISCIS 140 Query: 147 RDVAASLAAHRDDPLQQWRPW--HFEGHRYWVMRLPAEALAQHDPFKLAAARSAYAAANM 204 + L + +W P GH+Y R+ L Q PF + A M Sbjct: 141 LEARKQLDNNLKKINSRWSPLPGGLNGHKYLARRVTESELVQKSPFVMLNKEVPNAYKRM 200 Query: 205 ASQSLLLTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 L A + F L+ N + SAE + DH+C Sbjct: 201 GDYGL----AVVQQSDNSFVLLATQFNPLTLNRASAEEIQDHEC 240 >ECs4843 [I] COG2134 CDP-diacylglycerol pyrophosphatase Ecs Escherichia coli O157:H7 Length = 251 Score = 145 bits (367), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 79/218 (36%), Positives = 112/218 (51%), Gaps = 6/218 (2%) Query: 33 LWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPTRRLTGIESPELL 92 L +I ++C+P+ Q + P PCA V G+V+LKDL GP QYLLMPT R+ G ESP L Sbjct: 34 LRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLT 93 Query: 93 EPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHLHIDCMRRDVAAS 152 +P PN++ AWQ R +++ G+ + D + + +NS GR+Q H H+HI C+R DV Sbjct: 94 DPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQ 153 Query: 153 LAAHRDDPLQQWRPW--HFEGHRYWVMRLPAEALAQHDPFKLAAARSAYAAANMASQSLL 210 L + + +W P GH Y R+ L Q PF + A A +M S L Sbjct: 154 LDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGL- 212 Query: 211 LTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 A + F L+ N + SAE + DH C Sbjct: 213 ---AMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQC 247 >Zcdh [I] COG2134 CDP-diacylglycerol pyrophosphatase EcZ Escherichia coli O157:H7 EDL933 Length = 251 Score = 145 bits (366), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 79/218 (36%), Positives = 112/218 (51%), Gaps = 6/218 (2%) Query: 33 LWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPTRRLTGIESPELL 92 L +I ++C+P+ Q + P PCA V G+V+LKDL GP QYLLMPT R+ G ESP L Sbjct: 34 LRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLT 93 Query: 93 EPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHLHIDCMRRDVAAS 152 +P PN++ AWQ R +++ G+ + D + + +NS GR+Q H H+HI C+R DV Sbjct: 94 DPSXPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQ 153 Query: 153 LAAHRDDPLQQWRPW--HFEGHRYWVMRLPAEALAQHDPFKLAAARSAYAAANMASQSLL 210 L + + +W P GH Y R+ L Q PF + A A +M S L Sbjct: 154 LDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGL- 212 Query: 211 LTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 A + F L+ N + SAE + DH C Sbjct: 213 ---AMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQC 247 >cdh [I] COG2134 CDP-diacylglycerol pyrophosphatase Eco Escherichia coli K12 Length = 251 Score = 144 bits (363), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 78/218 (35%), Positives = 111/218 (50%), Gaps = 6/218 (2%) Query: 33 LWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPTRRLTGIESPELL 92 L +I ++C+P+ Q + P PCA V G+V+LKDL GP QYLLMPT R+ G ESP L Sbjct: 34 LRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLT 93 Query: 93 EPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHLHIDCMRRDVAAS 152 +P PN++ AWQ R +++ G+ + D + + +NS GR+Q H H+HI C+R DV Sbjct: 94 DPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVRKQ 153 Query: 153 LAAHRDDPLQQWRPW--HFEGHRYWVMRLPAEALAQHDPFKLAAARSAYAAANMASQSLL 210 L + + +W P GH Y R+ L Q PF + A A +M L Sbjct: 154 LDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGRYGL- 212 Query: 211 LTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 A + F L+ N + SAE + DH C Sbjct: 213 ---AMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQC 247 >STM4064 [I] COG2134 CDP-diacylglycerol pyrophosphatase Sty Salmonella typhimurium LT2 Length = 251 Score = 143 bits (360), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 83/225 (36%), Positives = 109/225 (48%), Gaps = 6/225 (2%) Query: 26 MAADPHKLWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPTRRLTG 85 + +P L EI +QC+P P PCA V G+V+ KD GP QYLLMPT R+ G Sbjct: 25 FSGNPDALREIVLEQCLPDQLQHQNPAPCAEVKPRAGYVVFKDRHGPLQYLLMPTYRING 84 Query: 86 IESPELLEPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHLHIDCM 145 ESP LLEP PN++ AWQ R +++ G + D + + +NS GRSQ HLH+HI C+ Sbjct: 85 TESPLLLEPATPNFFWLAWQARGYMSKKYGHDIPDSAVSLAINSRLGRSQDHLHIHISCI 144 Query: 146 RRDVAASLAAHRDDPLQQWRPW--HFEGHRYWVMRLPAEALAQHDPFKLAAARSAYAAAN 203 R DV L +W P GH Y R+ LAQ PF + A A + Sbjct: 145 RPDVREQLDNDLTRISTRWLPLPGGLMGHEYLARRVTESELAQRSPFMMLAEEVPEARDH 204 Query: 204 MASQSLLLTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 M +L A F L+ N + SAE + DH C Sbjct: 205 MGRYAL----AVVRQSDDSFVLLATERNLLTFNRASAEEIQDHSC 245 >Rv2289 [I] COG2134 CDP-diacylglycerol pyrophosphatase Mtu Mycobacterium tuberculosis H37Rv Length = 260 Score = 94.0 bits (232), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 72/240 (30%), Positives = 102/240 (42%), Gaps = 30/240 (12%) Query: 21 PPRPAMAADPHKLWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPT 80 P RP AD LW+I +C + +G PC VD G + K P Q+LL+P Sbjct: 34 PNRPE--ADREALWKIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKADFDPYQFLLIPL 91 Query: 81 RRLTGIESPELLEPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHL 140 R+TGIE P L E NY AW R V L +L + + + +N R+Q LH+ Sbjct: 92 ARITGIEDPALRESAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHI 151 Query: 141 HIDCMRRDVAASLAAHRDDPLQQWR--PWHFEGHRYWVMRLPAEALAQHDPF-----KLA 193 HI C +A+L W+ P G R+ + + +A + F K+ Sbjct: 152 HISCSSPTTSAALRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVT 211 Query: 194 A-----ARSAYAAANMASQSLLLTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 A ++ A AN+A LL A+G + PV +AE L DHDC Sbjct: 212 ADGKKMENASIAVANVAQDQFLLL---LAEGTE-----DQPV--------AAETLQDHDC 255 >MT2346 [I] COG2134 CDP-diacylglycerol pyrophosphatase MtC Mycobacterium tuberculosis CDC1551 Length = 260 Score = 94.0 bits (232), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 72/240 (30%), Positives = 102/240 (42%), Gaps = 30/240 (12%) Query: 21 PPRPAMAADPHKLWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPT 80 P RP AD LW+I +C + +G PC VD G + K P Q+LL+P Sbjct: 34 PNRPE--ADREALWKIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKADFDPYQFLLIPL 91 Query: 81 RRLTGIESPELLEPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHL 140 R+TGIE P L E NY AW R V L +L + + + +N R+Q LH+ Sbjct: 92 ARITGIEDPALRESAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHI 151 Query: 141 HIDCMRRDVAASLAAHRDDPLQQWR--PWHFEGHRYWVMRLPAEALAQHDPF-----KLA 193 HI C +A+L W+ P G R+ + + +A + F K+ Sbjct: 152 HISCSSPTTSAALRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVT 211 Query: 194 A-----ARSAYAAANMASQSLLLTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 A ++ A AN+A LL A+G + PV +AE L DHDC Sbjct: 212 ADGKKMENASIAVANVAQDQFLLL---LAEGTE-----DQPV--------AAETLQDHDC 255 >ML1417 [I] COG2134 CDP-diacylglycerol pyrophosphatase Mle Mycobacterium leprae Length = 268 Score = 92.4 bits (228), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 67/240 (27%), Positives = 97/240 (40%), Gaps = 28/240 (11%) Query: 21 PPRPAMAADPHKLWEITSQQCVPHMQASGQPQPCAMVDLARGFVILKDLVGPAQYLLMPT 80 PP AA LW+I +C Q +G PC +VD G + K P QYLL+P Sbjct: 29 PPNNPSAATRDALWKIVHDRCELGYQHTGAYAPCTLVDEQAGTALFKANYDPNQYLLLPL 88 Query: 81 RRLTGIESPELLEPQAPNYWAYAWQQRARVAQTLGRALSDEQLGVEVNSAAGRSQLHLHL 140 R+TGIE P L E +PNY AW R V+ L +L + + + +N R+Q LH+ Sbjct: 89 ARVTGIEDPALQELASPNYLYNAWAARGFVSSRLNNSLPEPDIFLAINPKNARTQDQLHI 148 Query: 141 HIDCMRRDVAASLAAHRDDPLQQWRPW--HFEGHRYWVMRLPAEALAQHDPFKLAAAR-- 196 HI C+ A L W+P + H Y + + F+ + Sbjct: 149 HISCVSPTTAEILKQVNWAEYVGWKPLPVTLQDHTYQALAVNRSTFESKSLFRDIQTKVT 208 Query: 197 --------SAYAAANMASQSLLLTGARFADGGSGFFLVNMPVNFDLQEQGSAEVLMDHDC 248 ++ A AN+A LL A + + +AE L DH+C Sbjct: 209 ADGNTMDHASVAVANIAPDQFLLLVAEGTE----------------DQAIAAEELQDHNC 252