BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0191.p (195 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cj1424c [G] COG0279 Phosphoheptose isomerase Cje Campylobacter j... 176 3e-44 CAC3054 [G] COG0279 Phosphoheptose isomerase Cac Clostridium ace... 172 3e-43 jhp0791 [G] COG0279 Phosphoheptose isomerase jHp Helicobacter py... 159 3e-39 aq_908 [G] COG0279 Phosphoheptose isomerase Aae Aquifex aeolicus 159 5e-39 HP0857 [G] COG0279 Phosphoheptose isomerase Hpy Helicobacter pyl... 156 2e-38 Cj1149c [G] COG0279 Phosphoheptose isomerase Cje Campylobacter j... 153 2e-37 sll0083 [G] COG0279 Phosphoheptose isomerase Syn Synechocystis 152 6e-37 TVN0956 [G] COG0279 Phosphoheptose isomerase Tvo Thermoplasma vo... 143 3e-34 Ta0854 [G] COG0279 Phosphoheptose isomerase Tac Thermoplasma aci... 138 9e-33 Rv0113 [G] COG0279 Phosphoheptose isomerase Mtu Mycobacterium tu... 137 1e-32 >Cj1424c [G] COG0279 Phosphoheptose isomerase Cje Campylobacter jejuni Length = 201 Score = 176 bits (446), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 90/195 (46%), Positives = 119/195 (61%) Query: 1 MHSAVETLRKNMNASIEAKQGFLLREEQLDIFEQAVRTVIERYKRGGRLYIAGNGGSAAD 60 M + ++ + SI K+ L E + + + A VI+ YK G + +AGNGGSAAD Sbjct: 1 MENLNSYIKGHFADSILVKEQILKDENLITLIKNASLEVIKAYKNGNKTLLAGNGGSAAD 60 Query: 61 AQHLAAEFVSKLARDRAPLPAEALTVDTSILTAIGNDYGYEQVFSRQIAGKMTDKDVFLG 120 AQH+A EFVS+ DR + + ALT DTSILTAIGNDYGYE +F+RQ+ + DVF+G Sbjct: 61 AQHIAGEFVSRFYFDRPGIASIALTTDTSILTAIGNDYGYENLFARQVQAQGVKGDVFIG 120 Query: 121 ITTSGQSPNILKALETCRQMGIPSVVFAGRDGGLAKAAADYCVVASGEMTSTIQEIHIVL 180 I+TSG S NILKALE C+Q I S+ +G GG DYC+ T IQE HI++ Sbjct: 121 ISTSGNSKNILKALEFCKQKEIISIGLSGASGGAMNELCDYCIKVPSTCTPRIQEAHILI 180 Query: 181 AHTLCECVERAVFEK 195 H +C VE +F K Sbjct: 181 GHIICAIVEEELFGK 195 >CAC3054 [G] COG0279 Phosphoheptose isomerase Cac Clostridium acetobutylicum Length = 196 Score = 172 bits (437), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 82/182 (45%), Positives = 121/182 (66%) Query: 12 MNASIEAKQGFLLREEQLDIFEQAVRTVIERYKRGGRLYIAGNGGSAADAQHLAAEFVSK 71 + +SIEAK+ L + ++ + V VI+ YK G ++ + GNGGSAAD+QH+AAEFVSK Sbjct: 9 IKSSIEAKEKILKDGQYIEQIQSIVEIVIQAYKLGKKVLLCGNGGSAADSQHIAAEFVSK 68 Query: 72 LARDRAPLPAEALTVDTSILTAIGNDYGYEQVFSRQIAGKMTDKDVFLGITTSGQSPNIL 131 DR LPA ALTV+TS+LT+IGNDY Y+ +F RQ+ + DV +GI+TSG S NI Sbjct: 69 FRLDRKALPAIALTVNTSVLTSIGNDYSYKNIFERQVEAFGKEGDVLIGISTSGNSENIT 128 Query: 132 KALETCRQMGIPSVVFAGRDGGLAKAAADYCVVASGEMTSTIQEIHIVLAHTLCECVERA 191 A + +++GI ++ F G+DGG K D+ ++ E T +QE HI++ H +C+ VE+ Sbjct: 129 LAFKKAKEIGITTIGFLGKDGGENKNYCDFPLIVPSEDTPRVQEAHIMIGHIVCDIVEKE 188 Query: 192 VF 193 +F Sbjct: 189 LF 190 >jhp0791 [G] COG0279 Phosphoheptose isomerase jHp Helicobacter pylori J99 Length = 192 Score = 159 bits (403), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 73/161 (45%), Positives = 105/161 (65%) Query: 30 DIFEQAVRTVIERYKRGGRLYIAGNGGSAADAQHLAAEFVSKLARDRAPLPAEALTVDTS 89 D +Q+V +IE + G++ I GNGGSA+DAQH AAE + +R L +L+ DTS Sbjct: 26 DALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSVISLSTDTS 85 Query: 90 ILTAIGNDYGYEQVFSRQIAGKMTDKDVFLGITTSGQSPNILKALETCRQMGIPSVVFAG 149 LTAI NDYGYE+VF+RQ+ +D+ +GI+TSG S N+LKA E + +G+ ++ AG Sbjct: 86 ALTAIANDYGYEEVFARQVEALGNKEDILIGISTSGNSKNVLKAYEKAKDLGMKTLSLAG 145 Query: 150 RDGGLAKAAADYCVVASGEMTSTIQEIHIVLAHTLCECVER 190 RDGG K +D ++ T IQE+HI++ H LC+C+ER Sbjct: 146 RDGGKMKPLSDIALIVPSGDTPRIQEMHILMIHILCDCIER 186 >aq_908 [G] COG0279 Phosphoheptose isomerase Aae Aquifex aeolicus Length = 191 Score = 159 bits (401), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 84/192 (43%), Positives = 114/192 (59%), Gaps = 4/192 (2%) Query: 5 VETLRKNMNASIEAKQGFL-LREEQLDIFEQAVRTVIERYKRGGRLYIAGNGGSAADAQH 63 +E ++K S E K F+ L +Q+ + T + K G ++ + GNGGSAADAQH Sbjct: 2 LEKVKKIFRESAEVKLAFVELYAQQIVDVAGIIATAL---KDGNKVLLFGNGGSAADAQH 58 Query: 64 LAAEFVSKLARDRAPLPAEALTVDTSILTAIGNDYGYEQVFSRQIAGKMTDKDVFLGITT 123 +AAE V + ++R PLPA ALT DTSILTA+GNDYG+E +F RQ+ DV +GITT Sbjct: 59 IAAELVGRFKKERRPLPAIALTTDTSILTALGNDYGFETIFERQVEALCMPGDVAIGITT 118 Query: 124 SGQSPNILKALETCRQMGIPSVVFAGRDGGLAKAAADYCVVASGEMTSTIQEIHIVLAHT 183 SG S N+++ L+ +G ++ F GR+GG A Y + T IQE HI L H Sbjct: 119 SGNSENVIRGLKKAHDLGATTIAFTGRNGGKVAQIAHYTFIVPSYETQRIQECHITLGHV 178 Query: 184 LCECVERAVFEK 195 LCE VE V E+ Sbjct: 179 LCELVEEMVCER 190 >HP0857 [G] COG0279 Phosphoheptose isomerase Hpy Helicobacter pylori 26695 Length = 192 Score = 156 bits (395), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 77/180 (42%), Positives = 110/180 (61%), Gaps = 8/180 (4%) Query: 19 KQGFLLREEQLD--------IFEQAVRTVIERYKRGGRLYIAGNGGSAADAQHLAAEFVS 70 K+ FL +E L+ +Q+V +IE + G++ I GNGGSA+DAQH AAE Sbjct: 7 KKEFLAHKEALEKSLEGLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTG 66 Query: 71 KLARDRAPLPAEALTVDTSILTAIGNDYGYEQVFSRQIAGKMTDKDVFLGITTSGQSPNI 130 + +R L A +L D S LTAI NDYGYE+VF+RQ+ DV +GI+TSG S N+ Sbjct: 67 RYKLERKGLSAISLNTDISALTAIANDYGYEEVFARQVEALGVKNDVLIGISTSGNSKNV 126 Query: 131 LKALETCRQMGIPSVVFAGRDGGLAKAAADYCVVASGEMTSTIQEIHIVLAHTLCECVER 190 LKA E + + + ++ AGRDGG K +D ++ + T IQE+HI++ H LC+C+ER Sbjct: 127 LKAYEKAKDLEMKTLSLAGRDGGKMKPLSDMALIVPSDDTPRIQEMHILMIHILCDCIER 186 >Cj1149c [G] COG0279 Phosphoheptose isomerase Cje Campylobacter jejuni Length = 186 Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 70/153 (45%), Positives = 106/153 (69%) Query: 39 VIERYKRGGRLYIAGNGGSAADAQHLAAEFVSKLARDRAPLPAEALTVDTSILTAIGNDY 98 + E K+GG++ I GNGGSAADAQH AAE + ++R L ALT DTS L+AIGNDY Sbjct: 33 LCECLKKGGKILICGNGGSAADAQHFAAELSGRYKKERKALAGIALTTDTSALSAIGNDY 92 Query: 99 GYEQVFSRQIAGKMTDKDVFLGITTSGQSPNILKALETCRQMGIPSVVFAGRDGGLAKAA 158 G+E VFSRQ+ +KDV +GI+TSG+SPN+L+AL+ +++ + + +G+ GG+ Sbjct: 93 GFEFVFSRQVEALGNEKDVLIGISTSGKSPNVLEALKKAKELNMLCLGLSGKGGGMMNKL 152 Query: 159 ADYCVVASGEMTSTIQEIHIVLAHTLCECVERA 191 D+ +V + T+ IQE+HI++ HTLC+ ++ + Sbjct: 153 CDHNLVVPSDDTARIQEMHILIIHTLCQIIDES 185 >sll0083 [G] COG0279 Phosphoheptose isomerase Syn Synechocystis Length = 194 Score = 152 bits (383), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 73/163 (44%), Positives = 107/163 (65%) Query: 33 EQAVRTVIERYKRGGRLYIAGNGGSAADAQHLAAEFVSKLARDRAPLPAEALTVDTSILT 92 E V + +R++ G +L I GNGGSAADAQHLAAEFV + +R LPA ALT ++SILT Sbjct: 25 EAVVDLICQRFQAGNKLLICGNGGSAADAQHLAAEFVGRFHFNRQALPAIALTANSSILT 84 Query: 93 AIGNDYGYEQVFSRQIAGKMTDKDVFLGITTSGQSPNILKALETCRQMGIPSVVFAGRDG 152 ++ NDY Y+ VFSRQ+ D+ G++TSG+S N+L AL+ + G+ ++ AG +G Sbjct: 85 SVSNDYTYDIVFSRQVEALGQPGDILWGLSTSGKSTNVLHALKCAKDKGLHTIGMAGNNG 144 Query: 153 GLAKAAADYCVVASGEMTSTIQEIHIVLAHTLCECVERAVFEK 195 GL + ADY + + + T IQE+H++ H +CE VE +F + Sbjct: 145 GLFQEFADYPLFVADKNTPCIQEVHLMTYHHICEQVESRLFAQ 187 >TVN0956 [G] COG0279 Phosphoheptose isomerase Tvo Thermoplasma volcanium Length = 182 Score = 143 bits (360), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 69/165 (41%), Positives = 99/165 (60%) Query: 25 REEQLDIFEQAVRTVIERYKRGGRLYIAGNGGSAADAQHLAAEFVSKLARDRAPLPAEAL 84 R L+ E+ R ++ + GG+L + GNGGSAAD+QH AE +++R LPA AL Sbjct: 15 RSIDLNHIEKIGRDIVNVFNSGGKLIVFGNGGSAADSQHFVAELSGHFSKERKALPAMAL 74 Query: 85 TVDTSILTAIGNDYGYEQVFSRQIAGKMTDKDVFLGITTSGQSPNILKALETCRQMGIPS 144 TV+TS LTAI NDY Y+ VFSRQ+ D +GI+TSG S N++K LE +++G + Sbjct: 75 TVNTSALTAISNDYSYDVVFSRQLEAFAKPGDYVVGISTSGNSVNVVKGLERAKELGCKT 134 Query: 145 VVFAGRDGGLAKAAADYCVVASGEMTSTIQEIHIVLAHTLCECVE 189 + GR GG A+ ++ E+TS IQE HI H +C ++ Sbjct: 135 LAMTGRSGGKIAKVAEEAIMIDSEVTSIIQEAHIAAIHMICSVID 179 >Ta0854 [G] COG0279 Phosphoheptose isomerase Tac Thermoplasma acidophilum Length = 182 Score = 138 bits (347), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 63/144 (43%), Positives = 92/144 (63%) Query: 46 GGRLYIAGNGGSAADAQHLAAEFVSKLARDRAPLPAEALTVDTSILTAIGNDYGYEQVFS 105 G +L + GNGGSAADAQH AE ++R PL A ALT +TS +TAI NDY Y+ VFS Sbjct: 36 GNKLIVFGNGGSAADAQHFVAELTGHFMKERKPLAAIALTTNTSSITAIANDYSYDVVFS 95 Query: 106 RQIAGKMTDKDVFLGITTSGQSPNILKALETCRQMGIPSVVFAGRDGGLAKAAADYCVVA 165 RQ+ DV +GI+TSG S N+++ +++ +++G ++ F GR GG K AD + Sbjct: 96 RQVEALAKPGDVVVGISTSGNSKNVIEGIKSAKRIGCHTIAFTGRSGGQLKGVADETLNV 155 Query: 166 SGEMTSTIQEIHIVLAHTLCECVE 189 ++TS IQE+HI + H +C ++ Sbjct: 156 DSDLTSIIQEMHITVIHMICAMID 179 >Rv0113 [G] COG0279 Phosphoheptose isomerase Mtu Mycobacterium tuberculosis H37Rv Length = 196 Score = 137 bits (345), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 71/167 (42%), Positives = 97/167 (58%), Gaps = 4/167 (2%) Query: 31 IFEQAVRTVIER----YKRGGRLYIAGNGGSAADAQHLAAEFVSKLARDRAPLPAEALTV 86 + +A R + +R Y+ G R+++ GNGGSAADAQH AAE L DR PL AEAL Sbjct: 26 VLLEAARAIGDRLIAGYRAGARVFMCGNGGSAADAQHFAAELTGHLIFDRPPLGAEALHA 85 Query: 87 DTSILTAIGNDYGYEQVFSRQIAGKMTDKDVFLGITTSGQSPNILKALETCRQMGIPSVV 146 ++S LTA+ NDY Y+ VF+R + G D I+TSG S ++L+A +T R++G+ V Sbjct: 86 NSSHLTAVANDYDYDTVFARALEGSARPGDTLFAISTSGNSMSVLRAAKTARELGVTVVA 145 Query: 147 FAGRDGGLAKAAADYCVVASGEMTSTIQEIHIVLAHTLCECVERAVF 193 G GG AD+ + T IQE HIV H + E VE A+F Sbjct: 146 MTGESGGQLAEFADFLINVPSRDTGRIQESHIVFIHAISEHVEHALF 192