BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0175.p (1405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO3247 [U] COG3210 Large exoproteins involved in heme utilizati... 160 3e-38 PA4541 [U] COG3210 Large exoproteins involved in heme utilizatio... 128 1e-28 PA4625 [U] COG3210 Large exoproteins involved in heme utilizatio... 115 5e-25 PA4082 [U] COG3210 Large exoproteins involved in heme utilizatio... 114 2e-24 RSp1444 [U] COG3210 Large exoproteins involved in heme utilizati... 110 2e-23 HI0264 [U] COG3210 Large exoproteins involved in heme utilizatio... 91 2e-17 PA0690 [U] COG3210 Large exoproteins involved in heme utilizatio... 79 9e-14 >YPO3247 [U] COG3210 Large exoproteins involved in heme utilization or adhesion Ype Yersinia pestis Length = 1910 Score = 160 bits (404), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 161/565 (28%), Positives = 245/565 (43%), Gaps = 107/565 (18%) Query: 46 RISVATAAVCGAWQAPVLAAAPAPGTLPTGWSVVNGNVTFTQNGNILNINQLSPQAIAQF 105 R+++ T G + VLA LP VV G Q + L + Q + + + Sbjct: 51 RLAMMTGLALGIFPLLVLAHP----VLPVNGHVVIGQGMLDQQSSTLTVTQQTDKLAINW 106 Query: 106 LSFSIGADATVNVNQPSAAAALLAKVSGGDISQIYGKLSATGTVVLYNPNGVVIGPSGSI 165 SF I +V QP + + L +V G SQIYG+L A G V L NP G++ G + Sbjct: 107 DSFDIAHGHSVIYAQPGSQSIALNQVQGQSASQIYGRLQANGQVFLLNPRGILFGKEAQV 166 Query: 166 DAGRFIATSLAISDSDFLAGKLNFARQGNAGIVDNQGKIQSATGGSVYLIGSSVSN--SG 223 + G +A++ +S+ +FL+G + G + NQ ++SA GG + L+G+ + N SG Sbjct: 167 NVGGLVASTKYMSNPEFLSGDYRLIGGESEGNIINQANLRSAPGGYIALVGNRIDNQRSG 226 Query: 224 IIKSAQGEVILAAGETVTLADTATPGVTVNVTGS--AGNVTNLGSITAEAGRIGVAAG-- 279 I + QG +LA G +VTL + V + G A + N G I A+ G I + A Sbjct: 227 SITTPQGNTVLAVGHSVTLNLDHGNLLGVQIQGETVAALIQNGGLIQADGGVIQLTAKGK 286 Query: 280 ------LINNSGVINASSV-----------------------------------VREGGR 298 +I+N+G++ A + V EG R Sbjct: 287 DMLMDTVIDNTGILQAKGLSAKNGAIYLDGGGEGVVSQMGTIDVNNQQGRGGRAVVEGKR 346 Query: 299 IFLRASQNLNTSAS------------------------------SSIHADGSR---GGNI 325 I+L + N+ + S I SR GG+ Sbjct: 347 IYLNKNSNIKAKGTAGGGTVLVGGGWQGKDNQIRNATAVVMDKGSDIDVSASRNGPGGSA 406 Query: 326 ALVAQDQAFIDGDVSATGAP--GQGGFVETSGLKRL----DVVKAPTLGAGGTWLIDPSD 379 L ++D G++ A G P G GG VETS + L V + G+ G WL+DP++ Sbjct: 407 VLWSEDYTGFHGNIRARGGPQSGDGGQVETSSQRNLQAFGQVDASAVRGSAGYWLLDPAE 466 Query: 380 LEVVSGGSRT-VSTSTGN-------GSYAISANGSSSQIGADTIVGQLEAGVNVTLATGA 431 + +VS G+ + V T GN ++ + +QI +I QL +G NVT+ T Sbjct: 467 VTIVSSGAESGVMTKVGNIPAEFFSSAHIFIPTANITQILNSSINTQLNSGTNVTITTSN 526 Query: 432 D---GSQAGNITVSSAIVKEAGGAASLTLNAANNISINADIRSTSGALTLTLHTGTGEGV 488 G Q NITV + I K AG A+LTL A NI +N +I + +G L L L G Sbjct: 527 SSLTGCQWCNITVQADITKTAGADATLTLQADGNIVVNNNITADAGKLNLNLLAGN---- 582 Query: 489 DFSAARQSTIGNGARISLNGGDLYA 513 + A + N +++ LNGGD A Sbjct: 583 --TTADSAITLNNSKVLLNGGDFLA 605 >PA4541 [U] COG3210 Large exoproteins involved in heme utilization or adhesion Pae Pseudomonas aeruginosa Length = 1417 Score = 128 bits (321), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 139/445 (31%), Positives = 216/445 (48%), Gaps = 58/445 (13%) Query: 13 RRLTLSWRARKPLPQLLAGLLRRSWTRLLAPALRISVATAAVCGAW-QAPVLAAAPAPGT 71 + TL W + + RR AL VA A++ G + QAP A Sbjct: 3 KSYTLVWNQATGCWNVASEGTRRRSKSGRGKAL--VVAGASLLGLFCQAPAFA------- 53 Query: 72 LPTGWSVVNGNVTF--TQNGNILNINQLSPQAIAQFLSFSIGADATVNVNQPSAAAALLA 129 LP+G +VV+G+ F + +G + I+Q S + I + FS+ AD V+ +QP A L Sbjct: 54 LPSGATVVSGDAGFQTSTDGRHMVIDQQSHKLITNWNEFSVRADERVSFHQPGQDAVALN 113 Query: 130 KVSGGDISQIYGKLSATGTVVLYNPNGVVIGPSGSIDAGRFIATSLAISDSDFLAGKLNF 189 +V G + S I G++ A G V L NPNGVV G S ++ G +A++L ++D DFLAG F Sbjct: 114 RVIGRNGSDIQGRIDANGKVFLVNPNGVVFGKSAQVNVGGLVASTLDLADRDFLAGNYQF 173 Query: 190 ARQGNAG-IVDNQGKIQSATGGSVYLIGSSVSNSGIIKSAQGEVILAAGETVTLADTATP 248 + G++G V N G +Q++ GGS+ L+G+ VSN G+I++ G+V L AG+ + L + Sbjct: 174 S--GDSGATVSNAGSLQASEGGSIALLGARVSNDGLIQAQLGDVALGAGQGINL-NFDGD 230 Query: 249 GVTVNVTGSAGNVTNL----GSITAEAGRIGVAAG--------LINNSGVINASSVVREG 296 G+ +N+ G+V L G I A+ G++ ++A ++NN G + A ++ Sbjct: 231 GL-LNLQVDKGSVDALAHNGGLIRADGGQVLMSARSADSLLKTVVNNQGTLEARTLRSAE 289 Query: 297 GRIFLRASQNLNTSASSSIHADGSRGGNIALVAQDQAFIDGDVSATGAPGQGGFVETSGL 356 GRI L DG G + + + A G + QG VE Sbjct: 290 GRIVL----------------DGGEQGTVRVAGKQDASAIGGGNGGLVLNQGANVEIQRT 333 Query: 357 KRLDVVKAPTLGAGGTWLIDPSDLEVVSGGSRTVSTSTGNGSYAIS-ANGSSSQIGAD-- 413 ++D GA GTW I ++ V + G + + G+GS + A G + +D Sbjct: 334 AQVDT--HADQGATGTWRILSHEVSVAAVGQ---ANAAGDGSGQVHVAQGPAGANASDSN 388 Query: 414 --TIVGQLEAGVNVTLATGADGSQA 436 TIV Q A V LA GA+G+ A Sbjct: 389 GVTIVQQQPA---VDLAAGANGTSA 410 >PA4625 [U] COG3210 Large exoproteins involved in heme utilization or adhesion Pae Pseudomonas aeruginosa Length = 2154 Score = 115 bits (289), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 152/504 (30%), Positives = 222/504 (44%), Gaps = 114/504 (22%) Query: 73 PTGWSVVNGNVTFTQNGNILNINQLSPQAIAQFLSFSIGADATVNVNQPSAAAALLAKVS 132 PTG + +Q G I+Q + +AI + F + AD V NQP ++ L +V+ Sbjct: 44 PTGAQFNPNEIKISQQGKTTLIDQSTQRAIINWKGFDVSADEAVRFNQPGVTSSTLNRVT 103 Query: 133 GGDISQIYGKLSATGTVVLYNPNGVVIGPSGSIDAGRFIATSLAISDSDFLAGKLNFARQ 192 G S I G++SA G V++YN NGVV S +D G I T+ ISD F GKL F + Sbjct: 104 AGQESVIAGRISAPGQVIIYNSNGVVFSGSAKVDVGSLITTTANISDEHFRQGKLIFDQP 163 Query: 193 GN--AGIVDNQGKIQSATGGSVYLIGSSVSNSGIIKSAQGEVILAAGETVTL-------- 242 GN A IV N G I A G + SV+N+G+I + G V +AAG T+ Sbjct: 164 GNPDARIV-NDGSISVAEKGLAAFVAPSVANNGVINARLGTVAMAAGNAATIDLYGDGLV 222 Query: 243 ADTATPGVTVNVTGSAGNVTNLGSITAEAGRIGVAA--------GLINNSGVINAS-SVV 293 + T VT + V+N G+I A+ G + + A +N SGVI A + V Sbjct: 223 SIAVTDPVTRKPQDAQALVSNGGAIQADGGSVLITAEQASRVVDNAVNLSGVILARGTEV 282 Query: 294 REG--------------GRI----------FLRASQNLNTSASSSIHADGS-RGGNIAL- 327 REG G+I L + Q + ++++SI A G+ +GG++ + Sbjct: 283 REGSVALVSKSGDIQIAGKIDVSGPKNGGDVLVSGQQVALASTASIDARGTAQGGSVRIG 342 Query: 328 ----------VAQDQAFIDG---DVSATGAPGQGG------------------------- 349 A++ G DVSATG G GG Sbjct: 343 GDFQGRGELPRAKNATLAKGASIDVSATG-KGNGGLAVVWSDGNTRMDGRILARGGAQGG 401 Query: 350 ---FVETSGLKRLDV-------VKAPTLGAGGTWLIDPSDLEVVSGGSRTVSTSTGNGSY 399 VETSG L + V AP G GGTWL+DP+ L +V+ G + S NG Sbjct: 402 NGGLVETSGKVNLSIADSAYVSVAAP-YGNGGTWLLDPTTLRIVASGGTSGSVGGANG-- 458 Query: 400 AISANGSSSQIGADTIVGQLEAGVNVTLATGADGSQAGNITVSSAIVKEAGGAASLTLN- 458 A+G ++ + A + G L AG VTL S + ++V + ++ G AS L Sbjct: 459 ---ASGDAT-VNASVVTGAL-AGGKVTL------SASDRLSVEAPLITSNLGGASRGLEL 507 Query: 459 ----AANNISINADIRSTSGALTL 478 A + I+A I +G+L + Sbjct: 508 IATGPAGAVDISAPILFRNGSLAI 531 >PA4082 [U] COG3210 Large exoproteins involved in heme utilization or adhesion Pae Pseudomonas aeruginosa Length = 1018 Score = 114 bits (284), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 136/451 (30%), Positives = 213/451 (47%), Gaps = 62/451 (13%) Query: 72 LPTGWSVV----NGNVTFTQNGNILNINQLSPQAIAQFLSFSIGADATVNVNQPSAAAAL 127 LP+G +VV NG + + GN L++NQ + IA + SFS+ A V NQPS+++ Sbjct: 54 LPSGGTVVGGSANGEIHLS-GGNSLSVNQKVDKLIANWDSFSVAAGERVIFNQPSSSSIA 112 Query: 128 LAKVSGGDISQIYGKLSATGTVVLYNPNGVVIGPSGSIDAGRFIATSLAISDSDF--LAG 185 L +V G S I G++ A G V L NPNGV+ G ++ G +A++L I+D++F + Sbjct: 113 LNRVIGTKASDIQGRIDANGQVFLVNPNGVLFGRGAQVNVGGLVASTLDITDAEFNGNSS 172 Query: 186 KLNFARQGNAGIVDNQGKIQSATGGSVYLIGSSVSNSGIIKSAQGEVILAAGETVTLADT 245 + F G++++ G I +A GGS+ L+G+ V N G + + G V L AG +TL Sbjct: 173 RYRFTGPSTNGVLNHGGAITAAEGGSIALLGAQVDNRGTVLAQMGGVGLGAGSDLTLNFD 232 Query: 246 ATPGVTVNVTGSAGN--VTNLGSITAEAGRIGVAAG--------LINNSGVINASSVVRE 295 + + V N +N G + A+ GR+ +AA ++N+ G I A S+ + Sbjct: 233 GNKLLDIRVDAGVANALASNGGLLKADGGRVLMAARTANALLNTVVNSQGAIEARSLRGK 292 Query: 296 GGRIFLRASQNLNTSASSSIHADGSRGGNIALVAQDQAFIDGDVSATG--APGQGGFVET 353 GRI L DG G + + G +SA PG GG VE Sbjct: 293 NGRIVL----------------DGGPDGKV--------MVGGALSANALNGPGHGGTVEV 328 Query: 354 SGLKRLDVV---KAPTL---GAGGTWLIDPSDLEVVSGGSRTVSTSTGNGSYA--ISANG 405 G + ++V + TL G GTW I ++V R + S G +A +S N Sbjct: 329 RG-QAVEVALGTQVNTLASNGLNGTWKIAADKIDV-----RPSAVSDGVTVHADTLSRNL 382 Query: 406 SSSQIGADTIVGQLEAGVNVTLATGAD---GSQAGNITVSSAIVKEAGGAASLTLNAANN 462 +S+ I + G L+ +V A+G GS A ++T++ + +G A L L A Sbjct: 383 ASTNIELVSTKGDLDLDGSVNWASGNRLGLGSAA-DLTLNGRL-NASGAKAGLELKAEGA 440 Query: 463 ISINADIRSTSGALTLTLHTGTGEGVDFSAA 493 I IN I L + G G V+ +A+ Sbjct: 441 IDINDKIVLGGAGSALAMDAGEGHRVNGTAS 471 >RSp1444 [U] COG3210 Large exoproteins involved in heme utilization or adhesion Rso Ralstonia solanacearum Length = 1371 Score = 110 bits (276), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 89/237 (37%), Positives = 132/237 (55%), Gaps = 11/237 (4%) Query: 75 GWSVVNGNVTFTQNGNILNINQLSPQAIAQFLSFSIGADATVNVNQPSAAAALLAKVSGG 134 G +V +G+ + QNG I Q S + + +F I A TVN QP A A L +V+G Sbjct: 60 GGTVTSGSGSIGQNGTTTTITQTSSRLAIDWSAFGIQAGETVNFIQPGAGAIALNRVTGH 119 Query: 135 DISQIYGKLSATGTVVLYNPNGVVIGPSGSIDAGRFIATSLAISDSDFLAGKLNFARQGN 194 + + I G L+A GTV + NPNGV+ G ++ G +A++L +S++DF AG+ + Sbjct: 120 EATSILGSLNANGTVFILNPNGVLFGSGAQVNVGGLVASTLGLSNADFEAGRYALSGGST 179 Query: 195 AGIVDNQGKIQSATGGSVYLIGSSVSNSGIIKSAQGEVILA-AGE-TVTLADTATPGVTV 252 AG V NQG I +GG V LI +SV N+G I + +G V+LA AG T+TLAD + G T+ Sbjct: 180 AG-VTNQGTITVPSGGKVALIANSVDNAGNISAPRGSVLLAGAGNVTLTLADGSPLGYTI 238 Query: 253 NVTGSAGNVTNLGSITAEAGRIGVAA--------GLINNSGVINASSVVREGGRIFL 301 + + V N G I A+ GR+ + A ++N +GV+ A +V G I L Sbjct: 239 SAGAARTLVNNGGMIVADGGRVVLTARGLDSLSESVVNTTGVVRARTVGNNQGTIEL 295 >HI0264 [U] COG3210 Large exoproteins involved in heme utilization or adhesion Hin Haemophilus influenzae Length = 905 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 85/276 (30%), Positives = 128/276 (46%), Gaps = 23/276 (8%) Query: 45 LRISVATAAVCGAWQAPVLAAAPAPGTLPTGWSVVNGNVTFTQNGNILNINQLSPQAIAQ 104 +++V + + + A+A LP G SVV G + GN + I+Q +P Sbjct: 2 YKLNVISLIILTTYTGATYASAR---DLPQGSSVVVGEANVSTIGNKMTIDQKTPTTQID 58 Query: 105 FLSFSIGADATVNVNQPSAAAALLAKVSGGDISQIYGKLSATGTVVLYNPNGVVIGPSGS 164 + SF IG + V QP A + +V+GG+ SQI GKL+A G V L NPNGV+I Sbjct: 59 WHSFDIGQNKEVEFKQPDANSVAYNRVTGGNASQIQGKLTANGKVYLANPNGVIITQGAE 118 Query: 165 IDAGRFIATSLAIS--------DSDFLAGKLNFARQGNAGIVDNQGKIQSATGGSVYLIG 216 I+ AT+ + + + KL + G V N+GKI++ V L G Sbjct: 119 INVAGLFATTKDLERISENGNGNGNKFTRKLKDGQVVKEGQVINKGKIKAK--DFVVLNG 176 Query: 217 SSVSNSGIIKSA-QGEVILAAGE--TVTLADTATPGVTVNVTGSAGNVTNLGSITA---- 269 V N G I + G+V L++G T TL+D++ V + V N G I A Sbjct: 177 DKVINEGEIDATNNGKVYLSSGYNFTFTLSDSSIS-VALEDNAVQSIVQNEGIIKAGDIT 235 Query: 270 --EAGRIGVAAGLINNSGVINASSVVREGGRIFLRA 303 GR L+ N+GV+ A+ V + G++ L A Sbjct: 236 LNAKGRNQALDSLVMNNGVLEATKVSNKNGKVVLSA 271 >PA0690 [U] COG3210 Large exoproteins involved in heme utilization or adhesion Pae Pseudomonas aeruginosa Length = 4180 Score = 79.0 bits (193), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 88/296 (29%), Positives = 139/296 (46%), Gaps = 41/296 (13%) Query: 76 WSVVNGNVTFTQNGNI-LNINQLSPQAIAQFLSFSIGADATVNVNQPSAAAALLAKV--S 132 W G V G ++I Q + +A+ + +F++G + TV+ Q A ALL +V Sbjct: 141 WQNAKGPVQTQAAGKTTVSIEQTADKAVLNWETFNVGRNTTVDFQQ-HADWALLNRVNDP 199 Query: 133 GGDISQIYGKLSATGTVVLYNPNGVVIGPSGSIDAGRFIATSLAISDSDFLAGKLNFARQ 192 SQI G++ A GTV+L N NGVV S +D + ISD F L + Sbjct: 200 SARPSQIQGQIKADGTVMLVNRNGVVFSGSSQVDVRNLTVAAANISDEQFRQRGLYYDNA 259 Query: 193 GN---------AGIVDNQGKIQSAT-------GGSVYLIGSSVSNSGIIKSAQGEVILAA 236 G+ A V+ ++++A GG V L+GS V N+G I + +G+ +L+A Sbjct: 260 GSRPTFTDAAGAVRVEQGAQLRTAAPSGSTRGGGYVLLLGSEVDNAGSIVTPKGQTVLSA 319 Query: 237 GETV---------------TLADTATPGVTVNVTGSAGNVTNLGSITAEAGRIGVAAGLI 281 G++ T + PG + SAG V N G + A G I ++ + Sbjct: 320 GDSFVIRRGQGTDGNLTSTTRGNEVLPGFAAD--SSAGRVRNSGLVQAATGDISLSGREV 377 Query: 282 NNSGVINASSVVREGGRIFLRASQN--LNTSASSSIHADGSRGGNIALVAQDQAFI 335 +GV+ +SS V G + L+AS+ L A+S+I D S G+ AL +Q +A + Sbjct: 378 EQAGVLLSSSSVDSRGTLHLKASERITLAEGATSAILVDSS--GSAALDSQREALL 431