BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0166.p (1071 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1113 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1538 0.0 SMc01095 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizob... 1414 0.0 AGc4508 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacteri... 1351 0.0 PA2494 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1311 0.0 STM0351 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1207 0.0 PA3522 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1129 0.0 SMc03971 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizob... 1067 0.0 mlr3285 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 1058 0.0 BMEI1629 [V] COG0841 Cation/multidrug efflux pump Bme Brucella m... 914 0.0 mll7357 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 913 0.0 >RSp1113 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1069 Score = 1538 bits (3983), Expect = 0.0, Method: Compositional matrix adjust. Identities = 818/1042 (78%), Positives = 924/1042 (88%) Query: 1 MNISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIA 60 MN SKFF+DRPIFAGVLS L+LL G++++ +LPISEYPEVVPPSVVVRAQ+PGANPKVIA Sbjct: 1 MNFSKFFVDRPIFAGVLSTLILLIGIISIWRLPISEYPEVVPPSVVVRAQFPGANPKVIA 60 Query: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRL 120 ETVASPLEEQINGVENMLYMQSQANSDGNLT+TV F+LG DPDKAQQLVQNRVSQA+PRL Sbjct: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTVTVTFKLGTDPDKAQQLVQNRVSQAMPRL 120 Query: 121 PEDVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLF 180 P+ VQRLGVTT+KSSP LTMVVHL SP++RYD TYLRNYAVLNVKDRLARI GVG+V LF Sbjct: 121 PDVVQRLGVTTIKSSPDLTMVVHLLSPNDRYDMTYLRNYAVLNVKDRLARINGVGQVQLF 180 Query: 181 GSGNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQ 240 GSG+Y+MRVWLDPNKVA+RGLTA +VVRAIR+QNVQVAAGVIG SPS P T LQLSVNAQ Sbjct: 181 GSGDYSMRVWLDPNKVAERGLTANEVVRAIRDQNVQVAAGVIGGSPSLPGTDLQLSVNAQ 240 Query: 241 GRLKTEGEFRDIILKASPDGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGA 300 GRLKTE EF DIILK+SP+GA T L DVAR+ELAASEYGLRSLLDNK AVAIPIFQAPG+ Sbjct: 241 GRLKTEQEFGDIILKSSPNGAVTTLRDVARIELAASEYGLRSLLDNKQAVAIPIFQAPGS 300 Query: 301 NALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVII 360 NAL +S VR M EL DFP V Y IVYDPTQFVR+SIEAV HTLLEA+ALVV+VVI+ Sbjct: 301 NALQISDDVRKTMAELKEDFPEGVDYRIVYDPTQFVRSSIEAVTHTLLEAVALVVLVVIL 360 Query: 361 FLQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVE 420 FLQTWRAS+IPLLAVPVSIIGTF LML FG++INALSLFG+VLAIGIVVDDAIVVVENVE Sbjct: 361 FLQTWRASVIPLLAVPVSIIGTFGLMLMFGFSINALSLFGLVLAIGIVVDDAIVVVENVE 420 Query: 421 RNIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 RNI GLSPR+ATY+AM+EVSGPIIAIALTL+AVFVPLAFMTGLTGQFYKQFA+TI+IST Sbjct: 421 RNIADGLSPREATYKAMREVSGPIIAIALTLIAVFVPLAFMTGLTGQFYKQFALTISIST 480 Query: 481 VISAFNSLTLSPALAALLLKGHGDKPDWLTRQMDRFLGGFFIRFNRFFNRASDNYGHGVT 540 VISAFNSLTLSPALAALLLK H D L R M+R LG F FNR F AS++YG + Sbjct: 481 VISAFNSLTLSPALAALLLKSHDAPKDLLARVMERGLGWIFRPFNRVFGAASESYGRSTS 540 Query: 541 GVIKRKGATMGVYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDRSEEVMR 600 VI RK +G+Y+ L+ T + VPGGFVP QDKQYLV+FAQLP+GAS+DR+E+V+R Sbjct: 541 RVIGRKAVMLGIYLALIGLTALLFNRVPGGFVPMQDKQYLVSFAQLPDGASLDRTEDVIR 600 Query: 601 KMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNAIAASLN 660 +MSDI LK PGV SA+AFPGLSINGFTNS SAGIVFV LKPF++RK+ +LSG AIA LN Sbjct: 601 RMSDIALKHPGVESAVAFPGLSINGFTNSPSAGIVFVTLKPFDQRKTPNLSGGAIAGQLN 660 Query: 661 KKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAAAKEPAL 720 +++G+IK+AF AVFPPPPV GLGT+GGFKMQ+EDR ++GY +L A+QAFM+ A + P L Sbjct: 661 QQYGAIKDAFIAVFPPPPVQGLGTVGGFKMQLEDRGSVGYEQLFAASQAFMQKARQTPEL 720 Query: 721 GPMFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGRVYQVRA 780 GP FSSYQINVPQL+ +LDRVKAKQLG+PVTDVF+TMQIYLGSLYVNDFNRFGR YQV+ Sbjct: 721 GPSFSSYQINVPQLNADLDRVKAKQLGVPVTDVFDTMQIYLGSLYVNDFNRFGRTYQVKV 780 Query: 781 QADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADINGGPAP 840 QADAPFRA AEDI QLKTRN G+MVPLSS+++V Q FGP+MVVRYNGYTAADINGGPAP Sbjct: 781 QADAPFRAHAEDILQLKTRNTDGDMVPLSSLLRVSQGFGPDMVVRYNGYTAADINGGPAP 840 Query: 841 GYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFLVLAALY 900 GYSS QAQAAAER+A LP+G++FEWTDLTYQ+ILAGN+ VW+FP+ VLLVFLVLAA Y Sbjct: 841 GYSSGQAQAAAERIAREVLPKGVRFEWTDLTYQQILAGNSAVWIFPLCVLLVFLVLAAQY 900 Query: 901 ESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIVEFAREL 960 ESLTLPLAVILIVPMS+ AA+ GVW++HGDNNIFTQIGL+VLVGL+ KNAILIVEFAREL Sbjct: 901 ESLTLPLAVILIVPMSLFAAMLGVWISHGDNNIFTQIGLVVLVGLACKNAILIVEFAREL 960 Query: 961 EMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAVFFGMLG 1020 E+QGR+ V+AAIEA RLRLRPILMTSIAFIMGVVPLV S+GAG+EMRHAMG+AVF GMLG Sbjct: 961 ELQGRSIVEAAIEACRLRLRPILMTSIAFIMGVVPLVMSTGAGAEMRHAMGVAVFAGMLG 1020 Query: 1021 VTLFGLFLTPVFYVLLRTIDRR 1042 VTLFGLFLTPVFYV+LRT+ R Sbjct: 1021 VTLFGLFLTPVFYVVLRTLASR 1042 >SMc01095 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1061 Score = 1414 bits (3661), Expect = 0.0, Method: Compositional matrix adjust. Identities = 749/1068 (70%), Positives = 881/1068 (82%), Gaps = 10/1068 (0%) Query: 1 MNISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIA 60 MN S+FF+DRP+FAGVLSV++ + G++ M LPISEYPEVVPP +VVRAQYPGANP VIA Sbjct: 1 MNFSRFFVDRPVFAGVLSVIIFVAGLIGMTGLPISEYPEVVPPQIVVRAQYPGANPAVIA 60 Query: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRL 120 ETVA+PLEEQINGVE MLYMQSQA +DG +T+TV F LG DPD+AQQLVQNRVSQ PRL Sbjct: 61 ETVATPLEEQINGVEGMLYMQSQATADGLMTLTVTFELGTDPDQAQQLVQNRVSQGEPRL 120 Query: 121 PEDVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLF 180 PE+V+RLGVTT+KSSP LT+VVHL SP+ +YD YLRNY VLNVKDRLAR+ GVG+V +F Sbjct: 121 PEEVRRLGVTTVKSSPDLTLVVHLISPNGQYDINYLRNYGVLNVKDRLARVDGVGQVQIF 180 Query: 181 GSGNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQ 240 G G+Y+MRVW+DP K A+RGL A+D+ A+R QNVQ AAGVIGASPS P LQLSVNAQ Sbjct: 181 GGGDYSMRVWIDPEKAAERGLAASDIANAVRGQNVQAAAGVIGASPSVPGLDLQLSVNAQ 240 Query: 241 GRLKTEGEFRDIILKASPDGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGA 300 GRLKT +F DI++K+ G TRLGDVARVE+ A++Y LRSLLDNK AV + +FQAPG+ Sbjct: 241 GRLKTPEDFADIVVKSGESGEITRLGDVARVEMGAADYSLRSLLDNKAAVGMGVFQAPGS 300 Query: 301 NALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVII 360 NA+ +S V M EL P V Y IVYD TQFVRASIE+V+HTLLEAIALVV+VVI+ Sbjct: 301 NAIQISENVHKVMAELKQTMPDGVDYEIVYDTTQFVRASIESVIHTLLEAIALVVVVVIV 360 Query: 361 FLQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVE 420 FLQTWRASIIPL+AVPVSI+GTF++M FG++INALSLFG+VLAIGIVVDDAIVVVENVE Sbjct: 361 FLQTWRASIIPLVAVPVSIVGTFAVMYVFGFSINALSLFGLVLAIGIVVDDAIVVVENVE 420 Query: 421 RNIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 RNI GLSP ATYRAMQEVSGPIIAIAL LVAVFVPLAF+TGLTGQFY+QFA+TIAIST Sbjct: 421 RNISQGLSPVQATYRAMQEVSGPIIAIALVLVAVFVPLAFITGLTGQFYRQFALTIAIST 480 Query: 481 VISAFNSLTLSPALAALLLKGHGDKPDWLTRQMDRFLGGFFIRFNRFFNRASDNYGHGVT 540 VISA NSLTLSPALAALLLK H D LTR MD G FF FNRFF +S+ YG GV Sbjct: 481 VISALNSLTLSPALAALLLKDHHAPKDRLTRVMDGLFGWFFRGFNRFFGASSEAYGRGVG 540 Query: 541 GVIKRKGATMGVYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDRSEEVMR 600 G++ RK MGVYV+LL T + VPGGFVP QDKQYL+ FAQLP+ A++DRSE+V+R Sbjct: 541 GILTRKSLVMGVYVVLLGVTFVLFRAVPGGFVPAQDKQYLIGFAQLPDAATLDRSEDVIR 600 Query: 601 KMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNAIAASLN 660 +MS+I LK PGV AIAFPGLSINGFTNSS++GIVFV LKPFEER + +LSG AIA LN Sbjct: 601 RMSEIALKHPGVEHAIAFPGLSINGFTNSSNSGIVFVSLKPFEERTTPELSGGAIAMQLN 660 Query: 661 KKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAAAKEPAL 720 ++FG+I++AF A+FPPPPV GLGT GGFK+QIEDR+ LGY LD A +A + A P L Sbjct: 661 QEFGAIQDAFIAMFPPPPVQGLGTTGGFKLQIEDRNGLGYRTLDDATKAVLAKAMAAPEL 720 Query: 721 GPMFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGRVYQVRA 780 ++SS+QINVPQL +LDR KA+QLG+ VTDVF T+QIYLGSLYVNDFN FGR Y VR Sbjct: 721 AGLYSSFQINVPQLYADLDRTKARQLGVAVTDVFETLQIYLGSLYVNDFNAFGRTYSVRI 780 Query: 781 QADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADINGGPAP 840 QADA +R+ A+DI +LK R+ GEM+PLS+++ V+QT G E +RYNG+ AADINGGPAP Sbjct: 781 QADASYRSHADDIGKLKVRSQTGEMIPLSALLNVEQTVGAERAIRYNGFLAADINGGPAP 840 Query: 841 GYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFLVLAALY 900 G+SS QAQAA ER+AA TLP GI +EWTDLTYQ+ILAGN+G+ VFP+++LLV+LVLAA Y Sbjct: 841 GFSSGQAQAAIERIAAETLPPGISYEWTDLTYQQILAGNSGILVFPLALLLVYLVLAAQY 900 Query: 901 ESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIVEFAREL 960 ESL LP+A+ILIVPM I+AALTGVWLT GDNN+FTQIGL+VLVGLSAKNAILIVEFAREL Sbjct: 901 ESLLLPIAIILIVPMGIMAALTGVWLTGGDNNVFTQIGLIVLVGLSAKNAILIVEFAREL 960 Query: 961 EMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAVFFGMLG 1020 E+ G AV AAIEASRLRLRPILMTS+AFIMGVVPLVTS+GAG+EMR AMG+AVF GM+G Sbjct: 961 ELSGSNAVSAAIEASRLRLRPILMTSMAFIMGVVPLVTSTGAGAEMRSAMGVAVFAGMIG 1020 Query: 1021 VTLFGLFLTPVFYVLLRTI--DRRALHSASHHEAPMTAGTHIAHAAPG 1066 VT FG+F+TPVFYVL+R + ++ H+ +H EAP H APG Sbjct: 1021 VTAFGIFMTPVFYVLIRKLSGEKPLKHTGAHIEAP--------HLAPG 1060 >AGc4508 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1064 Score = 1351 bits (3497), Expect = 0.0, Method: Compositional matrix adjust. Identities = 724/1039 (69%), Positives = 861/1039 (82%) Query: 1 MNISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIA 60 MNIS+FF+DRP+FAGVLS+L+++ G+L M LPISEYPEVVPPSVVVRA YPGANP VIA Sbjct: 1 MNISRFFVDRPVFAGVLSILIVVAGLLGMRALPISEYPEVVPPSVVVRATYPGANPTVIA 60 Query: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRL 120 ETVA+PLEEQINGVE+MLYM SQA SDG LT+TV F+LG DPDKAQQLVQNRVSQA PRL Sbjct: 61 ETVATPLEEQINGVEDMLYMGSQATSDGVLTLTVTFKLGTDPDKAQQLVQNRVSQAEPRL 120 Query: 121 PEDVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLF 180 P +V+ LG+TT+KSSP MVV+L S + YD TYLRNYA LNVKDRLARI+GVG+V +F Sbjct: 121 PAEVRALGITTVKSSPDFIMVVNLVSKTDAYDITYLRNYATLNVKDRLARIEGVGQVQVF 180 Query: 181 GSGNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQ 240 G+G+Y+MRVWLDP KVA+ L A DV AIR+QNVQ AAGVIGASPS LQL+VNAQ Sbjct: 181 GAGDYSMRVWLDPQKVAEHDLAAADVSDAIRQQNVQAAAGVIGASPSPNGVDLQLNVNAQ 240 Query: 241 GRLKTEGEFRDIILKASPDGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGA 300 GRL T EF +II+K+ +G TRL DVAR+EL A++Y LRSLLD +PAVA+ + QAPG+ Sbjct: 241 GRLTTPEEFGNIIVKSGANGEITRLRDVARIELGAADYTLRSLLDGEPAVAVAVLQAPGS 300 Query: 301 NALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVII 360 NA++++ VRA M L P V Y IVYD T+FVR+SIE VV TLLEA+ LVV+VVI+ Sbjct: 301 NAIEIADNVRATMDNLQLAMPDGVKYEIVYDTTKFVRSSIEKVVDTLLEAVGLVVLVVIL 360 Query: 361 FLQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVE 420 FLQTWRASIIPL+AVPVSIIGTF++M FG++INAL+LFG+VLAIGIVVDDAIVVVENVE Sbjct: 361 FLQTWRASIIPLIAVPVSIIGTFAVMYAFGFSINALTLFGLVLAIGIVVDDAIVVVENVE 420 Query: 421 RNIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 RNI GLSPRDATY+AM+EVSGPIIAIAL LVAVFVPLAF++GL+GQFY+QFA+TIAIST Sbjct: 421 RNIENGLSPRDATYKAMREVSGPIIAIALVLVAVFVPLAFISGLSGQFYRQFALTIAIST 480 Query: 481 VISAFNSLTLSPALAALLLKGHGDKPDWLTRQMDRFLGGFFIRFNRFFNRASDNYGHGVT 540 VISA NSLTLSPALAALLLK HG DWLTR MD+ LG FF FNR F AS+ YG V Sbjct: 481 VISAINSLTLSPALAALLLKEHGAPKDWLTRFMDKILGWFFRGFNRAFGAASNGYGKTVG 540 Query: 541 GVIKRKGATMGVYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDRSEEVMR 600 G++ RK M VY+ L+AAT G+ VP GFVP QDKQYL+ FAQLP+GA++DR+E V++ Sbjct: 541 GLVTRKSLVMIVYMALVAATYGMFTTVPSGFVPAQDKQYLIGFAQLPDGATLDRTESVIK 600 Query: 601 KMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNAIAASLN 660 +MS I ++ PGV+ AIAFPGLSINGFT S++GIVF L FE+RK+ +LSG AIA LN Sbjct: 601 RMSAIAMETPGVSHAIAFPGLSINGFTIGSNSGIVFAVLDDFEKRKTPELSGGAIAMQLN 660 Query: 661 KKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAAAKEPAL 720 +KF I++AF A+FPPPPV GLG GGFK+QIEDR GY LD+AA+A + A + P L Sbjct: 661 QKFAGIQDAFIAMFPPPPVNGLGQTGGFKLQIEDRAGYGYQTLDEAAKAVIAKAYQTPEL 720 Query: 721 GPMFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGRVYQVRA 780 +FSS+QINVPQL +LDR KA+QLG+ V+DVF T+QIYLGSLYVNDFN FGR Y VR Sbjct: 721 AGIFSSFQINVPQLFADLDRAKAEQLGVSVSDVFQTLQIYLGSLYVNDFNAFGRTYSVRV 780 Query: 781 QADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADINGGPAP 840 QAD+ FRA AEDI +LK R+ G+M+PLS+++KV T GPE RYNG+ AADINGGPAP Sbjct: 781 QADSQFRAHAEDIGRLKVRSATGQMIPLSTLLKVDATTGPERTNRYNGFLAADINGGPAP 840 Query: 841 GYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFLVLAALY 900 G+SS QAQAA E++ A LP GI +EWTDLTYQ+ILAGN+ + VFP+++LLV+LVLAA Y Sbjct: 841 GFSSGQAQAAMEKILAENLPAGIDYEWTDLTYQQILAGNSSIVVFPLALLLVYLVLAAQY 900 Query: 901 ESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIVEFAREL 960 ESLTLP+A+ILIVP+ +LAALTGVWLT GDNNIFTQIGL+VLVGLSAKNAILIVEFAREL Sbjct: 901 ESLTLPIAIILIVPLGVLAALTGVWLTGGDNNIFTQIGLVVLVGLSAKNAILIVEFAREL 960 Query: 961 EMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAVFFGMLG 1020 E +GRT +QAA+EASRLRLRPILMTS+AFIMGVVPLV S+GAG+EMR AMG+AVF GM+G Sbjct: 961 EFEGRTPLQAAVEASRLRLRPILMTSLAFIMGVVPLVVSTGAGAEMRAAMGVAVFSGMIG 1020 Query: 1021 VTLFGLFLTPVFYVLLRTI 1039 VT FG+F+TPVFYVL+R + Sbjct: 1021 VTFFGIFMTPVFYVLVRKL 1039 >PA2494 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1062 Score = 1311 bits (3393), Expect = 0.0, Method: Compositional matrix adjust. Identities = 690/1063 (64%), Positives = 839/1063 (78%), Gaps = 15/1063 (1%) Query: 1 MNISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIA 60 MN S+FFI RPIFA VLS+L+L+GG +++ QLPISEYPEVVPP+VVVRA +PGANPKVI Sbjct: 1 MNFSQFFIQRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIG 60 Query: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRL 120 ETVASPLE+ I GVENMLYM SQ+ SDG LT+T+ F LG D D AQ VQNRV++ P+L Sbjct: 61 ETVASPLEQAITGVENMLYMSSQSTSDGKLTLTITFALGTDLDNAQVQVQNRVTRTEPKL 120 Query: 121 PEDVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLF 180 PE+V RLG+T K+SP LTMVVHLTSPDNRYD YL NYAVLNVKD LAR+ GVG+V LF Sbjct: 121 PEEVTRLGITVDKASPDLTMVVHLTSPDNRYDMLYLSNYAVLNVKDELARLDGVGDVQLF 180 Query: 181 GSGNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQ 240 G G+Y++RVWLDPNKVA R LTATDVV AIREQN QVAAG +GA P+ +T QLS+N Q Sbjct: 181 GLGDYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGTLGAPPAPSDTSFQLSINTQ 240 Query: 241 GRLKTEGEFRDIILKASPDGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGA 300 GRL TE EF +II++A +G TRL D+ARVEL +++Y LRSLL+NKPAVAIPIFQ PG+ Sbjct: 241 GRLVTEEEFENIIIRAGANGEITRLRDIARVELGSNQYALRSLLNNKPAVAIPIFQRPGS 300 Query: 301 NALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVII 360 NA+++S VR M EL FP + YSIVYDPT FVR SIEAVVHTL EA+ LVV+VVI+ Sbjct: 301 NAIEISNLVREKMAELKHSFPQGMDYSIVYDPTIFVRGSIEAVVHTLFEALVLVVLVVIL 360 Query: 361 FLQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVE 420 FLQTWRASIIPL AVPVS+IGTF++M G+++NALSLFG+VLAIGIVVDDAIVVVENVE Sbjct: 361 FLQTWRASIIPLAAVPVSLIGTFAVMHMLGFSLNALSLFGLVLAIGIVVDDAIVVVENVE 420 Query: 421 RNIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 RNIG GL P +AT RAM+EV+GPIIA AL L AVF+P AF++GLTGQFY+QFA+TIAIST Sbjct: 421 RNIGLGLKPVEATKRAMREVTGPIIATALVLCAVFIPTAFISGLTGQFYRQFALTIAIST 480 Query: 481 VISAFNSLTLSPALAALLLKGHGDKPDWLTRQMDRFLGGFFIR-FNRFFNRASDNYGHGV 539 VISAFNSLTLSPALAA+LLKGH + D + +D+ LG + R FNRFF+RAS HG Sbjct: 481 VISAFNSLTLSPALAAVLLKGHHEPKDRFSVFLDKLLGSWLFRPFNRFFDRAS----HGY 536 Query: 540 TGVIKR--KGATMGVYV---LLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDR 594 G + R +G+++ + V L++ G S P GFVP QDKQYLVAFAQLP+ AS+DR Sbjct: 537 VGTVNRVLRGSSIALLVYGGLMVLTYFGFSS-TPTGFVPQQDKQYLVAFAQLPDAASLDR 595 Query: 595 SEEVMRKMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNA 654 +E V+++MS+I L +PGVA ++AFPGLSINGFTNS ++GIVF LKPF+ERK S A Sbjct: 596 TEAVIKQMSEIALAQPGVADSVAFPGLSINGFTNSPNSGIVFTPLKPFDERKDPSQSAGA 655 Query: 655 IAASLNKKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAA 714 IAA+LN K+ I++A+ A+FPPPPV GLGT+GGF++QIEDR GY EL K Q + A Sbjct: 656 IAAALNAKYADIQDAYIAIFPPPPVQGLGTIGGFRLQIEDRGNQGYEELFKQTQNIITKA 715 Query: 715 AKEPALGP--MFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRF 772 P L P +FSSYQ+NVPQ+D ++DR KAK G+ ++D+F+T+Q+YLGSLY NDFNRF Sbjct: 716 RALPELEPSSVFSSYQVNVPQIDADIDREKAKTHGVAISDIFDTLQVYLGSLYANDFNRF 775 Query: 773 GRVYQVRAQADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAA 832 GR YQV QA+ FR + E I QLK RN+ GEMVPL+S +KV T GP+ V+ YNG+ A Sbjct: 776 GRTYQVNVQAEQQFRLEPEQIGQLKVRNNLGEMVPLASFIKVSDTSGPDRVMHYNGFITA 835 Query: 833 DINGGPAPGYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLV 892 ++NG PA GYSS QAQAA E++ LP G+ +EWT+LTYQ+ILAGN ++VFP+ VLL Sbjct: 836 ELNGAPAAGYSSGQAQAAIEKLLKEELPNGMTYEWTELTYQQILAGNTALFVFPLCVLLA 895 Query: 893 FLVLAALYESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAIL 952 FLVLAA YES +LPLAVILIVPM++L+A+TGV L DNNIFTQIGL+VLVGL+ KNAIL Sbjct: 896 FLVLAAQYESWSLPLAVILIVPMTLLSAITGVILAGSDNNIFTQIGLIVLVGLACKNAIL 955 Query: 953 IVEFARELEMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGI 1012 IVEFA++ + +G V A +EA RLRLRPILMTSIAFIMGVVPLV S+GAG+EMRHAMG+ Sbjct: 956 IVEFAKDKQEEGMDRVAAVLEACRLRLRPILMTSIAFIMGVVPLVISTGAGAEMRHAMGV 1015 Query: 1013 AVFFGMLGVTLFGLFLTPVFYVLLRTI--DRRALHSASHHEAP 1053 AVF GM+GVT FGL LTPVFYVL+R +R A +A+ P Sbjct: 1016 AVFSGMIGVTFFGLLLTPVFYVLIRRFVENREARRAANDKGLP 1058 >STM0351 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1055 Score = 1207 bits (3124), Expect = 0.0, Method: Compositional matrix adjust. Identities = 620/1053 (58%), Positives = 782/1053 (74%), Gaps = 3/1053 (0%) Query: 1 MNISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIA 60 M + FFI RPIFA VLS+L+LL G +A L+LP+SEYP V PP+V V A YPGANP+VIA Sbjct: 1 MKFTHFFIARPIFAIVLSLLMLLAGAIAFLKLPLSEYPAVTPPTVQVSASYPGANPQVIA 60 Query: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRL 120 +TVA+PLE+ INGV+ MLYM +Q DG + I++ F G DPD AQ VQNRVS+ALPRL Sbjct: 61 DTVAAPLEQVINGVDGMLYMNTQMAIDGRMVISIAFEQGTDPDMAQIQVQNRVSRALPRL 120 Query: 121 PEDVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLF 180 PE+VQR+GV T K+SP + MVVHL SP RYD+ YL N+A+ V+D LAR+ GVG+V ++ Sbjct: 121 PEEVQRIGVVTEKTSPDMLMVVHLVSPQKRYDSLYLSNFAIRQVRDELARLPGVGDVLVW 180 Query: 181 GSGNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQ 240 G+G YAMRVWLDP K+A RGLTA+D+V A+REQNVQVAAG +G P + Q++VN Sbjct: 181 GAGEYAMRVWLDPAKIANRGLTASDIVTALREQNVQVAAGSVGQQPEA-SAAFQMTVNTL 239 Query: 241 GRLKTEGEFRDIILKASPDGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGA 300 GRL +E +F +I++K DG TRL DVARV L A Y LRSLL+ + A A+ I Q+PGA Sbjct: 240 GRLTSEEQFGEIVVKIGADGEVTRLRDVARVTLGADAYTLRSLLNGEAAPALQIIQSPGA 299 Query: 301 NALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVII 360 NA+DVS +R M EL +FP + Y I YDPT FVRAS+++V TLLEA+ LVV+VV++ Sbjct: 300 NAIDVSNAIRGKMDELQQNFPQDIEYRIAYDPTVFVRASLQSVAITLLEALVLVVLVVVM 359 Query: 361 FLQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVE 420 FLQTWRASIIPL+AVPVS++GTF+LM FG+++N LSLFG+VL+IGIVVDDAIVVVENVE Sbjct: 360 FLQTWRASIIPLVAVPVSLVGTFALMHLFGFSLNTLSLFGLVLSIGIVVDDAIVVVENVE 419 Query: 421 RNIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 R+I G SP +A +AM EV+GPI++I L AVF+P AF+ GL G+FY+QFA+TIAIST Sbjct: 420 RHISQGKSPGEAAKKAMDEVTGPILSITSVLTAVFIPSAFLAGLQGEFYRQFALTIAIST 479 Query: 481 VISAFNSLTLSPALAALLLKGHGD--KPDWLTRQMDRFLGGFFIRFNRFFNRASDNYGHG 538 ++SA NSLTLSPALAA+LL+ H D K DWLTR M GGFF RFNRFF+ AS+ Y Sbjct: 480 ILSAINSLTLSPALAAILLRPHHDTAKADWLTRLMGTVTGGFFHRFNRFFDSASNRYVSA 539 Query: 539 VTGVIKRKGATMGVYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDRSEEV 598 V ++ M +Y + T + VP GFVP QDK YLV AQLP+GAS+DR+E V Sbjct: 540 VRRAVRGSVIVMVLYAGFVGLTWLGFHQVPNGFVPAQDKYYLVGIAQLPSGASLDRTEAV 599 Query: 599 MRKMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNAIAAS 658 +++MS I L EPGV S + FPGLS+NG N ++ ++F LKPF+ER+ LS NAIA Sbjct: 600 VKQMSAIALAEPGVESVVVFPGLSVNGPVNVPNSALMFAMLKPFDEREDPSLSANAIAGK 659 Query: 659 LNKKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAAAKEP 718 L KF I + F +FPPPPV GLG GGFK+QIEDR LG+ + K M A + P Sbjct: 660 LMHKFSHIPDGFIGIFPPPPVPGLGATGGFKLQIEDRAELGFEAMTKVQSEIMSKAMQTP 719 Query: 719 ALGPMFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGRVYQV 778 L M +S+Q N PQL V++DRVKAK +G+ +TD+F T+QI LGSLYVNDFNRFGR ++V Sbjct: 720 ELANMLASFQTNAPQLQVDIDRVKAKSMGVSLTDIFETLQINLGSLYVNDFNRFGRAWRV 779 Query: 779 RAQADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADINGGP 838 AQADAPFR + EDI LK RN GEM+PLS+ V + + GP+ ++ YNG+ + DI+GGP Sbjct: 780 MAQADAPFRMQQEDIGLLKVRNAKGEMIPLSAFVTIMRQSGPDRIIHYNGFPSVDISGGP 839 Query: 839 APGYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFLVLAA 898 APG+SS QA A E++ TLP G+ FEWTDL YQ+ AGN+ + +F ++VLL FL+LAA Sbjct: 840 APGFSSGQATDAIEKIVRETLPEGMVFEWTDLVYQEKQAGNSALAIFALAVLLAFLILAA 899 Query: 899 LYESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIVEFAR 958 Y S +LP AV+LI PMS+L+A+ GVW++ GDNNIFTQIG +VLVGL+AKNAILIVEFAR Sbjct: 900 QYNSWSLPFAVLLIAPMSLLSAIVGVWVSGGDNNIFTQIGFVVLVGLAAKNAILIVEFAR 959 Query: 959 ELEMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAVFFGM 1018 E G + A +EASRLRLRPILMTS AFI GVVPLV ++GAG+EMRHAMGIAVF GM Sbjct: 960 AKEHDGADPLTAVLEASRLRLRPILMTSFAFIAGVVPLVLATGAGAEMRHAMGIAVFAGM 1019 Query: 1019 LGVTLFGLFLTPVFYVLLRTIDRRALHSASHHE 1051 LGVTLFGL LTPVFYV++R + + + H+ Sbjct: 1020 LGVTLFGLLLTPVFYVVVRRMALKRENRVDSHD 1052 >PA3522 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1053 Score = 1129 bits (2921), Expect = 0.0, Method: Compositional matrix adjust. Identities = 611/1059 (57%), Positives = 770/1059 (72%), Gaps = 18/1059 (1%) Query: 1 MNISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIA 60 M +FFIDRPIFA VLSVL+++GG+++ QLP+SEYP V PP+V V YPGANP VIA Sbjct: 1 MTFPRFFIDRPIFAIVLSVLMMIGGIVSFFQLPLSEYPAVTPPTVQVTTAYPGANPDVIA 60 Query: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRL 120 +TVA+PLE+ I GVE MLYM SQ+ +DG + +T+ F +DPD AQ VQNRVS+ L RL Sbjct: 61 QTVATPLEQAITGVEGMLYMSSQSATDGRMILTITFDQHIDPDMAQIQVQNRVSRVLSRL 120 Query: 121 PEDVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLF 180 P++VQR GV T K+SP + MVVHL SP+ RYD Y+ NYA L V+D L R+ G+ +V ++ Sbjct: 121 PDEVQRQGVVTQKTSPDILMVVHLLSPEQRYDPLYISNYAYLQVRDELLRLPGISDVVVW 180 Query: 181 GSGNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQ 240 G+G Y+MR+WLDP+ +A RGLTA +V+ A+REQNVQVAAG +G +P S Q++VN Sbjct: 181 GAGEYSMRLWLDPDLIAARGLTAGEVIAAVREQNVQVAAGAVGQAPDS-TAAFQVTVNTL 239 Query: 241 GRLKTEGEFRDIILKASPDGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGA 300 GRL E +F DII++ DG TRL DVAR+E+ Y LRSLLD +PAVA+ I Q+PGA Sbjct: 240 GRLSDEEQFGDIIVRTGADGQVTRLRDVARIEMGGDAYALRSLLDGEPAVALQIIQSPGA 299 Query: 301 NALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVII 360 NALD + VRA + L +FP+ +S I YDPT FVRAS++ V TLLEAI LVV+VV++ Sbjct: 300 NALDTAEAVRATVARLEGNFPAGLSARIAYDPTVFVRASLQTVATTLLEAILLVVVVVVL 359 Query: 361 FLQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVE 420 FL++WRAS+IPL+AVPVS++GTF++M G+++N LSLFG+VL+IGIVVDDAIVVVENVE Sbjct: 360 FLRSWRASLIPLMAVPVSLVGTFAVMHLMGFSLNTLSLFGLVLSIGIVVDDAIVVVENVE 419 Query: 421 RNIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 R+I G P A RAM EV+GPI+AI L AVF+P AF++GL G+FY+QFA+TIAIST Sbjct: 420 RHIENGEPPLQAARRAMDEVTGPIMAITSVLAAVFIPTAFLSGLQGEFYRQFALTIAIST 479 Query: 481 VISAFNSLTLSPALAALLLKGHGDKPDWLTRQMDRFLGGFFIRFNRFFNR----ASDNYG 536 ++SA NSLTLSPALA LLL+ R + G F R + R A + YG Sbjct: 480 ILSALNSLTLSPALAGLLLR---------PRPAGGAVAGRFQRLLQVLGRPLRNAPEAYG 530 Query: 537 HGVTGVIKRKGATMGVYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDRSE 596 + V V++ G + VY LL T VP GFVP QDK YLV AQLPNGAS++R++ Sbjct: 531 NAVRKVVRVSGLALVVYGGLLGLTWVGFQAVPPGFVPMQDKYYLVGIAQLPNGASLERTD 590 Query: 597 EVMRKMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNAIA 656 V+R+MS I L EPGV S +AFPGLS+NGF N +A ++F L PFE R S DL AIA Sbjct: 591 AVVRQMSRIGLDEPGVESVVAFPGLSVNGFVNVPNAAVMFFMLDPFESRTSADLGALAIA 650 Query: 657 ASLNKKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAAAK 716 L +F SI + F VFPPPPV GLGT+GGFKMQ+EDR G L + Q M A + Sbjct: 651 GRLQARFASIPDGFLGVFPPPPVPGLGTIGGFKMQVEDRGGAGLEALARQTQVLMMKATE 710 Query: 717 EPALGPMFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGRVY 776 LG + +S+ IN PQL+V +DR K K G+ + DVF +Q+YLGSLY+NDFNRFGR Y Sbjct: 711 SGQLGGLMTSFDINAPQLEVVVDRTKVKSQGVRLADVFEALQVYLGSLYINDFNRFGRTY 770 Query: 777 QVRAQADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADING 836 +V AQADAP R +AE I +L+ RN AG M+PLSS V V + GP+ V+ YNGY +ADI+G Sbjct: 771 KVTAQADAPHRMQAEAIGRLQVRNAAGAMLPLSSFVTVTPSSGPDRVIHYNGYPSADISG 830 Query: 837 GPAPGYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFLVL 896 G PG SS QA A ER+A LP G+ FEWTDLTYQ+ LAGN+ +++FP+ VLL +L+L Sbjct: 831 GALPGVSSGQAVALMERLAGEVLPEGMTFEWTDLTYQQKLAGNSALFIFPLCVLLAYLIL 890 Query: 897 AALYESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIVEF 956 AA Y S LPLAV+LIVPM +L+A+ GVWL GDNN+F QIGL+VLVGL+AKNAILIVEF Sbjct: 891 AAQYNSWLLPLAVLLIVPMCLLSAIAGVWLVGGDNNVFVQIGLVVLVGLAAKNAILIVEF 950 Query: 957 ARELEMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAVFF 1016 AR LE +G A++A +EA RLRLRPILMTS+AFI GVVPLV +SGAG+EMR AMG+AVF Sbjct: 951 ARTLEAEGARALEAVVEACRLRLRPILMTSLAFIAGVVPLVMASGAGAEMRQAMGVAVFA 1010 Query: 1017 GMLGVTLFGLFLTPVFYVLLRT----IDRRALHSASHHE 1051 GMLGVTLFGLFLTPVFYVL+R ++RRA S +H E Sbjct: 1011 GMLGVTLFGLFLTPVFYVLVRALAARLERRAGGSLAHLE 1049 >SMc03971 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1058 Score = 1067 bits (2760), Expect = 0.0, Method: Compositional matrix adjust. Identities = 545/1045 (52%), Positives = 741/1045 (70%), Gaps = 3/1045 (0%) Query: 1 MNISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIA 60 M + FF+DRPIFA VLS++LL+ G +A QLP+++YPE+ PP++VVRA YPGA+ + +A Sbjct: 1 MRFAHFFVDRPIFASVLSIVLLIVGSIAYFQLPVAQYPEIAPPTIVVRASYPGADAETVA 60 Query: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRL 120 TVA+PLE++INGVENMLYM S A +DG++ +T+ F+LG D D+AQ LVQNRVS A PRL Sbjct: 61 NTVATPLEQEINGVENMLYMSSYATADGSMALTITFKLGTDLDQAQVLVQNRVSIAEPRL 120 Query: 121 PEDVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLF 180 PE+V+R+GVTT KSSP L MVVHL SP++RYD Y+ NYA ++D L R+ GVG+V LF Sbjct: 121 PEEVRRIGVTTTKSSPDLMMVVHLLSPNDRYDQLYVSNYARTRIRDILVRLDGVGDVLLF 180 Query: 181 GSGNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQ 240 G YA+R+WLDP K++ G+TA DVV A+REQNVQV+ G IG P S ++ Q +V Sbjct: 181 GEREYALRIWLDPQKLSAYGMTAGDVVSALREQNVQVSGGSIGGPPMSSDSAFQYTVTTD 240 Query: 241 GRLKTEGEFRDIILKASPDGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGA 300 GR +FR +I+KA+ +G +L DVAR+EL A EY S L+ PAVA+ IF PG+ Sbjct: 241 GRFSDARQFRYVIVKATEEGRLVQLQDVARIELGAREYVTNSYLNGSPAVALGIFSRPGS 300 Query: 301 NALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVII 360 NAL + ++A M ELS DFP + Y I+Y+PT+F+ SI+ V T+ EA LV +VVI+ Sbjct: 301 NALAAADAIQATMTELSRDFPEGLEYRIIYNPTEFISESIDEVYKTIAEAALLVALVVIV 360 Query: 361 FLQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVE 420 FLQ+WR +IIP++A+PVS++GTF+L+ FG+++N L+LFG+VLAIGIVVDDAIVVVENVE Sbjct: 361 FLQSWRTAIIPIVAIPVSLVGTFALLYAFGFSLNMLTLFGLVLAIGIVVDDAIVVVENVE 420 Query: 421 RNIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 RN+ G++PR+A + M EV +IAI+L L AVFVP AF+ G+ GQFY QFA+TIA++T Sbjct: 421 RNLARGMTPREAAHVTMDEVGAAVIAISLVLTAVFVPTAFIPGIAGQFYLQFAVTIAVAT 480 Query: 481 VISAFNSLTLSPALAALLLKGHGDKPDWLTRQMDRFLGGFFIRFNRFFNRASDNYGHGVT 540 VISA NSLTLSPALAA+LL+ H + + R GF FNR F+R +D Y V Sbjct: 481 VISAVNSLTLSPALAAILLRPHENHDHESRNPLTRLGRGFANGFNRGFDRMADGYAWTVR 540 Query: 541 GVIKRKGATMG---VYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDRSEE 597 +++ + A G V+V LL AT ++ +VP GF+P D+ Y + QLP+GAS++R+++ Sbjct: 541 HLVRTRIALAGALLVFVALLGATWYMAQVVPRGFIPTMDQGYAIVVIQLPDGASLERTDK 600 Query: 598 VMRKMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNAIAA 657 V+R+ S+++ + PGV A+AF G + FTN+S++G++F FEER + S I Sbjct: 601 VVRRASEMIREVPGVKDAVAFAGFNGATFTNASNSGVIFTPFDSFEERLEQKQSAEQIIG 660 Query: 658 SLNKKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAAAKE 717 + I+EAF PPP V G+G GGFKMQI DR + A M AA + Sbjct: 661 QIFGAMQGIQEAFIIAVPPPSVRGIGNSGGFKMQIMDRQSADMRRALGLAYQMMGAANQT 720 Query: 718 PALGPMFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGRVYQ 777 L +F+++ + PQ + +DR KA+ L +P+ ++F T+ I LG+ YVNDFN FGRVYQ Sbjct: 721 EGLTGVFTTFTASSPQFFLAIDRDKARALNVPIPNIFETLSINLGTSYVNDFNAFGRVYQ 780 Query: 778 VRAQADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADINGG 837 VRAQAD FR + EDI LK R+ +G +VPL ++V+++ T GP +V RYN Y + + G Sbjct: 781 VRAQADQQFRLEREDILALKVRSASGALVPLGTLVEIRDTSGPALVQRYNMYVSVPVQGN 840 Query: 838 PAPGYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFLVLA 897 PAPG S+ A E +A LP+G FEWT+L Q+ GN V++F +SV+ VFL L+ Sbjct: 841 PAPGVSTGSALDKMEALAGQILPQGTTFEWTELALQERQTGNTAVFIFALSVVFVFLALS 900 Query: 898 ALYESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIVEFA 957 A YES LPLA+ILIVP+++LAAL GV + DNN+ TQIGL+VL+GL+AKNAILIVEFA Sbjct: 901 AQYESWVLPLAIILIVPLAVLAALLGVSIRGFDNNVLTQIGLIVLIGLAAKNAILIVEFA 960 Query: 958 RELEMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAVFFG 1017 R+ E +G+T ++AAI+ASRLRLRPILMT+ AFI+GVVPLV ++G G+EMR ++G AVF G Sbjct: 961 RQGEEEGKTPIEAAIDASRLRLRPILMTAFAFILGVVPLVIATGPGAEMRQSLGTAVFAG 1020 Query: 1018 MLGVTLFGLFLTPVFYVLLRTIDRR 1042 MLGVT GLFLTPVFYV LR++ R+ Sbjct: 1021 MLGVTFLGLFLTPVFYVALRSLRRK 1045 >mlr3285 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1067 Score = 1058 bits (2735), Expect = 0.0, Method: Compositional matrix adjust. Identities = 542/1068 (50%), Positives = 744/1068 (69%), Gaps = 10/1068 (0%) Query: 1 MNISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIA 60 M + FF+DRPIFA V+S++LL+ G +A QLP+++YPE+ PP++VVRAQYPGA+ + +A Sbjct: 1 MRFAHFFVDRPIFASVVSIVLLILGGIAYTQLPVAQYPEIAPPTIVVRAQYPGADAETVA 60 Query: 61 ETVASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRL 120 TVA+P+E++INGVE MLYM S ++ DG + +T+ F+LG D DKAQ LVQNRVS A PRL Sbjct: 61 ATVATPIEQEINGVEGMLYMSSYSSGDGAMALTITFKLGTDLDKAQVLVQNRVSVAEPRL 120 Query: 121 PEDVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLF 180 PE+V+RLG+TT KSSP L MVVH+ SPDN YD Y+ NYA V+D L R+ GVG++ +F Sbjct: 121 PEEVRRLGITTTKSSPDLMMVVHMLSPDNTYDQLYVSNYARSRVRDILLRLDGVGDLIIF 180 Query: 181 GSGNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQ 240 G Y++R+WLDP K++ G+T+ DVV+A+R+QNVQV+ G IGA P++ T Q +V Q Sbjct: 181 GEREYSLRIWLDPEKLSALGMTSGDVVQALRDQNVQVSGGSIGAPPTNTGTAFQYTVTTQ 240 Query: 241 GRLKTEGEFRDIILKASPDGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGA 300 GR +FR +I+K++ DG L DVAR+EL A +Y S L+ KPAVA+ IFQ PG Sbjct: 241 GRFNDARDFRYVIVKSTDDGRLISLQDVARIELGAKDYVTNSYLNGKPAVALAIFQRPGT 300 Query: 301 NALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVII 360 NAL + +++ MKELS DFP +SY IVY+PT+FV SI+ V T+LEA+ LV+IV+I+ Sbjct: 301 NALAAAAEIQDKMKELSRDFPKGLSYDIVYNPTEFVAESIQEVYKTILEAMLLVIIVIIV 360 Query: 361 FLQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVE 420 FLQ+WR +I+P++A+PVS+IGT +++ G+++N L+LFG+VLAIGIVVDDAIVVVENVE Sbjct: 361 FLQSWRMAIVPIVAIPVSLIGTLAVLYAAGFSLNMLTLFGLVLAIGIVVDDAIVVVENVE 420 Query: 421 RNIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 RNI +GL+P A++ M EV IIAI+L L+AVFVP AF+ G++GQFY QFA+TIA+ST Sbjct: 421 RNIASGLAPNPASHLTMNEVGTAIIAISLVLIAVFVPTAFVPGISGQFYLQFAITIAVST 480 Query: 481 VISAFNSLTLSPALAALLLKGH---GDKPDWLTRQMDRFLGGFFIRFNRFFNRASDNYGH 537 ISAFNSLTLSPALAALL K H P + + R L FNR F+R + Y Sbjct: 481 AISAFNSLTLSPALAALLFKPHHAAAAPPRFFLARFGRALAD---GFNRGFDRVAHWYSS 537 Query: 538 GVTGVIKRK---GATMGVYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDR 594 + ++ + A + V+ L+ AT+ + VP GF+P D+ Y + QLP+GA++ R Sbjct: 538 IIRVLVGSRIAIAAMLAVFAALIYATVYMVQAVPRGFIPSLDQGYAIVVVQLPDGAALSR 597 Query: 595 SEEVMRKMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNA 654 ++ V+++ S I+ K PGV A+AF G S FTN+S+ G++F KPF+ER S Sbjct: 598 TDAVIQQASQIIQKTPGVDYAVAFAGFSGATFTNASNQGVIFARFKPFDERLKAGQSATQ 657 Query: 655 IAASLNKKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAA 714 + +L SIKEAF PPPP+ G+G GGFK+QI++R++ ++ A A Sbjct: 658 VIGNLFGSLQSIKEAFIIALPPPPIRGVGNAGGFKLQIQERNSADMRQILALAYEIAGKA 717 Query: 715 AKEPALGPMFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGR 774 K P L +F+++ + PQ + +DR KA+ L +P+ ++F T+ I LG+ YVNDFN FGR Sbjct: 718 NKTPGLTGVFTTFSASSPQFFLAIDRDKARILNVPIPNIFETLSINLGTAYVNDFNAFGR 777 Query: 775 VYQVRAQADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADI 834 VYQVRAQAD FR DI +LK R+ G +VPL ++++++ GP +V RYN Y + + Sbjct: 778 VYQVRAQADQAFRLDRADILKLKVRSATGALVPLGTLIEIRDVTGPALVQRYNMYVSVPL 837 Query: 835 NGGPAPGYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFL 894 G APG S+ A A E + A TLP G +EWT+L YQ+ GNA V++F +SVL VFL Sbjct: 838 QGNAAPGVSTGDALALMEGITAKTLPAGTSYEWTELAYQEHNTGNAAVYIFGLSVLFVFL 897 Query: 895 VLAALYESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIV 954 LAA YES LP A++L+VP+ +LAAL GV DNNI QIGL+VL+GL+AKNAILIV Sbjct: 898 ALAAQYESWVLPFAIVLVVPLGVLAALLGVSFRGLDNNILVQIGLIVLIGLAAKNAILIV 957 Query: 955 EFARELEMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAV 1014 EFAR+ + +G +A +AA+EA RLRLRPILMT+ +FI+GVVPL+ ++G G+EMR ++G AV Sbjct: 958 EFARQAQERGLSAAEAAVEACRLRLRPILMTAFSFILGVVPLMIATGPGAEMRQSLGTAV 1017 Query: 1015 FFGMLGVTLFGLFLTPVFYVLLRTI-DRRALHSASHHEAPMTAGTHIA 1061 F GMLGVT GLFLTPVFYV LR++ RR + + P A + A Sbjct: 1018 FSGMLGVTFVGLFLTPVFYVALRSLFSRRKPRAEAEPSGPAEAPSETA 1065 >BMEI1629 [V] COG0841 Cation/multidrug efflux pump Bme Brucella melitensis Length = 1051 Score = 914 bits (2363), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/1036 (46%), Positives = 669/1036 (64%), Gaps = 13/1036 (1%) Query: 3 ISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIAET 62 +++FF+DRP+FA V+S++L+L G++ + LP+++YPE+ PP VVV A YPGA+ + +A+T Sbjct: 1 MNRFFVDRPVFAAVISIVLVLAGLICIRILPVAQYPELTPPQVVVSATYPGASAETVAQT 60 Query: 63 VASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRLPE 122 VA+PLE+QINGVENMLYMQS + G + +TV F LG DPD+A V NRV +A LP+ Sbjct: 61 VAAPLEQQINGVENMLYMQSSSLGSGTMQLTVTFALGTDPDQATINVNNRVQRATSSLPQ 120 Query: 123 DVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLFGS 182 +VQRLGVT K S T+ +V + + +RYD TY+ NYA+LNV D L R+ GVG+V L G+ Sbjct: 121 EVQRLGVTVDKRSTTILGMVAMFATTDRYDRTYVGNYALLNVVDDLKRLPGVGDVQLLGN 180 Query: 183 GNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQGR 242 +Y+MRVWL P+++AQ LT +DV AI+EQN Q AAG G P P + QGR Sbjct: 181 IDYSMRVWLRPDRLAQYNLTPSDVSAAIQEQNAQFAAGRFGDQPDPHAGPFTYTATTQGR 240 Query: 243 LKTEGEFRDIILKASP-DGATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGAN 301 L F +IIL++S + AT RL DVARVEL Y + S L+ PAV I I+ PGAN Sbjct: 241 LPDAAAFENIILRSSSQNAATLRLKDVARVELGTESYLVNSNLNGTPAVPIAIYLQPGAN 300 Query: 302 ALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVIIF 361 AL+ ++ M EL A FP+ + Y+I +D T+F++ SIE VVHT +EAI LVV+VV IF Sbjct: 301 ALNTMELIQNRMNELKASFPAGIDYAIPFDTTKFIKVSIEEVVHTFIEAIILVVLVVFIF 360 Query: 362 LQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVER 421 LQ WRA++IP++AVP+SIIGTF+ M G++IN L+LFG+VLAIGIVVDDAIVV+ENVER Sbjct: 361 LQNWRATLIPVIAVPISIIGTFAGMYVLGFSINLLTLFGLVLAIGIVVDDAIVVLENVER 420 Query: 422 NIGA-GLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST 480 + LSPR A +AM EV+GP+IAI L L AVF+P+AFM GL G+ YKQFA+TIAIS Sbjct: 421 IMTTEKLSPRKAAIKAMGEVTGPVIAIVLVLCAVFIPVAFMGGLVGEMYKQFAVTIAISV 480 Query: 481 VISAFNSLTLSPALAALLLKGHGDKPDWLTRQMDRFLGGFFIRFNRFFNRASDNYGHGVT 540 +S +LTL+PAL AL+LK +P R FNR F R + Y GV Sbjct: 481 TLSGLVALTLTPALCALILKPGHHEPILPFRI-----------FNRAFERVTSGYTRGVR 529 Query: 541 GVIKRKGATMGVYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDRSEEVMR 600 +KR + ++ LL +T + VPG +P +D+ +L A LP AS++R+ V+ Sbjct: 530 FFLKRATIGLIIFAGLLGSTYYLFERVPGSLLPDEDQGFLFGVAVLPPAASLERTTVVLD 589 Query: 601 KMSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNAIAASLN 660 ++S+ + K P V + A G + +SAG +F+ LK ++ER + D + ++ Sbjct: 590 QVSENIRKNPAVDNVFAVSGFDLLSGGLKTSAGTMFIMLKDWKERTTPDADARNLPRTIM 649 Query: 661 KKFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAAAKEPAL 720 IK+ F PPP+MGL T GGF++ ++DR G L +A + +AAAK P L Sbjct: 650 GMNAGIKDGMVLAFNPPPIMGLSTTGGFELYVQDRTGGGVESLTQATKLITEAAAKRPEL 709 Query: 721 GPMFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGRVYQVRA 780 + +++ VPQ D++LDR KAK +G+P+ VF MQ GSLYVNDF +GR YQV Sbjct: 710 QGVRTTFDPYVPQYDIQLDREKAKAMGVPINSVFTAMQATFGSLYVNDFTLYGRNYQVNL 769 Query: 781 QADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADINGGPAP 840 Q++A FR D+ + R D+G M+PL ++V VK+ GP+ + R+N + AA + G PAP Sbjct: 770 QSEAEFRRDPGDLKHVFVRADSGSMIPLDALVTVKRIVGPDQLERFNAFNAAKVTGNPAP 829 Query: 841 GYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFLVLAALY 900 GY+S A A + VAA LP+G + WT YQ++ G +++VFL+LAA Y Sbjct: 830 GYTSGDAIKAMQEVAAQVLPQGYQIAWTGSAYQEVSTSGTGSQAMIFGLIMVFLILAAQY 889 Query: 901 ESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIVEFAREL 960 E +LPLAVI VP +I AL L N+++ QIGL+ L+GL+ KNAILIVEFA Sbjct: 890 ERWSLPLAVITAVPFAIFGALLATDLRGLTNDVYFQIGLVTLIGLAVKNAILIVEFAVLE 949 Query: 961 EMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAVFFGMLG 1020 G++A++AA A+RLR RPI+MTS+ FI+GVVPL S+GAGS RH++G V GML Sbjct: 950 RESGKSAIEAAASAARLRFRPIVMTSLTFILGVVPLAVSTGAGSASRHSIGTGVIGGMLA 1009 Query: 1021 VTLFGLFLTPVFYVLL 1036 T F P+FY L+ Sbjct: 1010 ATFIATFFIPMFYSLI 1025 >mll7357 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1061 Score = 913 bits (2360), Expect = 0.0, Method: Compositional matrix adjust. Identities = 503/1056 (47%), Positives = 691/1056 (65%), Gaps = 17/1056 (1%) Query: 3 ISKFFIDRPIFAGVLSVLLLLGGVLAMLQLPISEYPEVVPPSVVVRAQYPGANPKVIAET 62 + FFI RPIFA ++++++L G + LP+S++P++ PP VVV A YPGA+ +V+A+T Sbjct: 4 VVNFFIHRPIFASAIAIIMVLAGTICYFLLPVSQFPDITPPQVVVSAHYPGASAQVVADT 63 Query: 63 VASPLEEQINGVENMLYMQSQANSDGNLTITVNFRLGVDPDKAQQLVQNRVSQALPRLPE 122 V +PLE+QINGV+ M YM S +++DG+ TIT+ F +G A VQNRVSQA LP Sbjct: 64 VTTPLEQQINGVQGMTYMSSTSSNDGSSTITITFDVGYSLSTAAVDVQNRVSQAASSLPA 123 Query: 123 DVQRLGVTTLKSSPTLTMVVHLTSPDNRYDTTYLRNYAVLNVKDRLARIQGVGEVGLFGS 182 V + GVT K +P ++V+LTSPD D L N A L V D L R+QGVG+V +FG Sbjct: 124 IVNQGGVTIKKQNPNFVLIVNLTSPDKSVDPVALSNLAYLQVVDPLKRLQGVGDVQIFGE 183 Query: 183 GNYAMRVWLDPNKVAQRGLTATDVVRAIREQNVQVAAGVIGASPSSPETPLQLSVNAQGR 242 Y+MR+WLDP+K+A G+TA DV AI EQNVQVAAG IG SP+ T ++ VNA GR Sbjct: 184 RRYSMRIWLDPDKLANLGITAVDVQNAIAEQNVQVAAGKIGQSPAPAGTAFEMQVNAVGR 243 Query: 243 LKTEGEFRDIILKASPD-GATTRLGDVARVELAASEYGLRSLLDNKPAVAIPIFQAPGAN 301 L EF DI+++A+ D G+ RL DVAR+EL A +Y + P V + ++Q PG+N Sbjct: 244 LSDPKEFGDIVVRANTDTGSLVRLRDVARIELGALQYSSSAFFGKDPTVVLAVYQMPGSN 303 Query: 302 ALDVSTQVRAAMKELSADFPSSVSYSIVYDPTQFVRASIEAVVHTLLEAIALVVIVVIIF 361 ALD+ +V+ M+ELSA FP VSY++ YD T+FV AS+ V+ TL EA+ LVV VV IF Sbjct: 304 ALDLQQRVKDKMQELSARFPKGVSYAMHYDTTRFVSASMHDVLITLGEALVLVVAVVFIF 363 Query: 362 LQTWRASIIPLLAVPVSIIGTFSLMLGFGYTINALSLFGMVLAIGIVVDDAIVVVENVER 421 LQ+WR +IIP +A+PVS++ T +M G+++N LSL GMVLAIG+VVDDAIVVVENVER Sbjct: 364 LQSWRTTIIPTIAIPVSLVATLVVMEMLGFSLNMLSLLGMVLAIGLVVDDAIVVVENVER 423 Query: 422 NIGAGLSPRDATYRAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAISTV 481 + AGL P AT AM EV+GPIIA L+AVFVP+AF+ G++G+ Y QFA+T+AIS Sbjct: 424 QLEAGLKPLAATKAAMAEVTGPIIATTAVLMAVFVPVAFIPGVSGRLYNQFALTVAISVG 483 Query: 482 ISAFNSLTLSPALAALLLKGHGDKPDWLTRQMDRFLGGFFIRFNRFFNRASDNYGHGVTG 541 ISAFNSLTLSPAL+A L+ H P + F FN F++ S Y HGV Sbjct: 484 ISAFNSLTLSPALSAAFLR-HRHGPQFF----------LFRWFNTGFDKISHAYAHGVRF 532 Query: 542 VIKRKGATMGVYVLLLAATLGISYIVPGGFVPGQDKQYLVAFAQLPNGASIDRSEEVMRK 601 +I+ + +G++ L AT + +P F+P +D+ Y QLP+GAS++R++ V +K Sbjct: 533 LIRLRWIMLGLFAAGLVATYFVWQKLPSTFLPVEDQGYFFVVIQLPDGASLERTDAVAQK 592 Query: 602 MSDIMLKEPGVASAIAFPGLSINGFTNSSSAGIVFVGLKPFEERKSKDLSGNAIAASLNK 661 DI+ PGV + GL+ S++ + F LKP+EER D S + + A + Sbjct: 593 ARDILQATPGVDIVGSISGLNFLTSAAQSNSAVEFAILKPWEER-GPDQSASKLVADVRG 651 Query: 662 KFGSIKEAFTAVFPPPPVMGLGTLGGFKMQIEDRDALGYAELDKAAQAFMKAAAKEPALG 721 K I EAF F PP + G+GT GGF+ +ED G L+ A QA + A K+P + Sbjct: 652 KLMQIPEAFALSFDPPSIPGIGTTGGFEFVVEDLTGRGSTALNDATQAVIAEARKQPEIN 711 Query: 722 P--MFSSYQINVPQLDVELDRVKAKQLGIPVTDVFNTMQIYLGSLYVNDFNRFGRVYQVR 779 P +FS + + PQ + +LDR KAK LG+ + DVFNT+QIYLGSLYVNDFN FGR ++V Sbjct: 712 PQQLFSPFSTSTPQFNYDLDRSKAKLLGLNLPDVFNTLQIYLGSLYVNDFNLFGRTFRVT 771 Query: 780 AQADAPFRAKAEDIAQLKTRNDAGEMVPLSSVVKVKQTFGPEMVVRYNGYTAADINGGPA 839 QAD RA A DI++L RN +G MVPLS++ K+ GPE V YN +A INGG A Sbjct: 772 IQADKDARAGAADISRLYVRNASGGMVPLSTLGKLVPFVGPETVPHYNNNASASINGGAA 831 Query: 840 PGYSSDQAQAAAERVAAATLPRGIKFEWTDLTYQKILAGNAGVWVFPISVLLVFLVLAAL 899 PG+SS QA AA ER AA LPR FEWT +T+Q++ AG+ VF ++++ VFL+LAA Sbjct: 832 PGFSSGQAVAAMERAAATALPRDFGFEWTGITFQELKAGSIASVVFGLAIVFVFLILAAQ 891 Query: 900 YESLTLPLAVILIVPMSILAALTGVWLTHGDNNIFTQIGLMVLVGLSAKNAILIVEFARE 959 YES +P V+L VP+++ A + + ++++QIG ++L+GL+AKNAILIVEFAR Sbjct: 892 YESWAMPFMVLLAVPLALFGAFAALSVRGMQIDVYSQIGFVMLIGLAAKNAILIVEFARR 951 Query: 960 LEMQGRTAVQAAIEASRLRLRPILMTSIAFIMGVVPLVTSSGAGSEMRHAMGIAVFFGML 1019 +G + V+AA+EA+RLRLRPILMT+ AFI+GV+PL+ ++GAG+ R ++G VF GM+ Sbjct: 952 RREEGLSIVEAAMEAARLRLRPILMTAFAFILGVLPLMFATGAGAASRQSIGTTVFGGMV 1011 Query: 1020 GVTLFGLFLTPVFYVLLRTIDRR--ALHSASHHEAP 1053 T+ L PVFY ++ + R + AS H P Sbjct: 1012 AATILSLVFVPVFYAVIEQLRERRGSGEPASKHTEP 1047