BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0125.p (206 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value coaE [H] COG0237 Dephospho-CoA kinase Eco Escherichia coli K12 190 2e-48 ZcoaE [H] COG0237 Dephospho-CoA kinase EcZ Escherichia coli O157... 190 2e-48 ECs0107 [H] COG0237 Dephospho-CoA kinase Ecs Escherichia coli O1... 190 2e-48 STM0140 [H] COG0237 Dephospho-CoA kinase Sty Salmonella typhimur... 187 1e-47 RSc2828 [H] COG0237 Dephospho-CoA kinase Rso Ralstonia solanacearum 187 2e-47 YPO3430 [H] COG0237 Dephospho-CoA kinase Ype Yersinia pestis 169 4e-42 PM0088 [H] COG0237 Dephospho-CoA kinase Pmu Pasteurella multocida 163 2e-40 HI0890m [H] COG0237 Dephospho-CoA kinase Hin Haemophilus influenzae 157 1e-38 VC2427 [H] COG0237 Dephospho-CoA kinase Vch Vibrio cholerae 156 3e-38 PA4529 [H] COG0237 Dephospho-CoA kinase Pae Pseudomonas aeruginosa 152 4e-37 >coaE [H] COG0237 Dephospho-CoA kinase Eco Escherichia coli K12 Length = 206 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 98/199 (49%), Positives = 136/199 (68%), Gaps = 1/199 (0%) Query: 7 RFTIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDA 66 R+ + LTGGIGSGK+TVA F LG ++D D IA + P A+ I +HFGA+ I A Sbjct: 2 RYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAA 61 Query: 67 RGAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVESGNW 126 G + R +R+ +F NPE ++ L A+LHPLI+ ET + A+ PYV++VVPLLVE+ + Sbjct: 62 DGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLY 121 Query: 127 VGRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDNGGAAD 186 +A+R+LVVD E Q+ R MQR+ + R+ VE I+AAQA+R+ARLAVA DV+DN GA D Sbjct: 122 -KKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPD 180 Query: 187 SLPERVRNLHSQYLALAAQ 205 ++ V LH+ YL LA+Q Sbjct: 181 AIASDVARLHAHYLQLASQ 199 >ZcoaE [H] COG0237 Dephospho-CoA kinase EcZ Escherichia coli O157:H7 EDL933 Length = 206 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 98/199 (49%), Positives = 136/199 (68%), Gaps = 1/199 (0%) Query: 7 RFTIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDA 66 R+ + LTGGIGSGK+TVA F LG ++D D IA + P A+ I +HFGA+ I A Sbjct: 2 RYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAA 61 Query: 67 RGAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVESGNW 126 G + R +R+ +F NPE ++ L A+LHPLI+ ET + A+ PYV++VVPLLVE+ + Sbjct: 62 DGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLY 121 Query: 127 VGRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDNGGAAD 186 +A+R+LVVD E Q+ R MQR+ + R+ VE I+AAQA+R+ARLAVA DV+DN GA D Sbjct: 122 -KKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPD 180 Query: 187 SLPERVRNLHSQYLALAAQ 205 ++ V LH+ YL LA+Q Sbjct: 181 AIASDVARLHAHYLQLASQ 199 >ECs0107 [H] COG0237 Dephospho-CoA kinase Ecs Escherichia coli O157:H7 Length = 206 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 98/199 (49%), Positives = 136/199 (68%), Gaps = 1/199 (0%) Query: 7 RFTIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDA 66 R+ + LTGGIGSGK+TVA F LG ++D D IA + P A+ I +HFGA+ I A Sbjct: 2 RYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAA 61 Query: 67 RGAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVESGNW 126 G + R +R+ +F NPE ++ L A+LHPLI+ ET + A+ PYV++VVPLLVE+ + Sbjct: 62 DGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLY 121 Query: 127 VGRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDNGGAAD 186 +A+R+LVVD E Q+ R MQR+ + R+ VE I+AAQA+R+ARLAVA DV+DN GA D Sbjct: 122 -KKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPD 180 Query: 187 SLPERVRNLHSQYLALAAQ 205 ++ V LH+ YL LA+Q Sbjct: 181 AIASDVARLHAHYLQLASQ 199 >STM0140 [H] COG0237 Dephospho-CoA kinase Sty Salmonella typhimurium LT2 Length = 206 Score = 187 bits (476), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 99/199 (49%), Positives = 138/199 (69%), Gaps = 1/199 (0%) Query: 7 RFTIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDA 66 R+T+ LTGGIGSGK+TVA+ F LG ++D D IA + P A+ I EHFG++ I A Sbjct: 2 RYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQPALNAIAEHFGSELIAA 61 Query: 67 RGAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVESGNW 126 G + R +R+ +F +PE + L A+LHPLI+ ET R + A+ PYV++VVPLLVE+ + Sbjct: 62 DGTLRRRALRERIFSHPEEKAWLNALLHPLIQQETQRQFQQATSPYVLWVVPLLVENRLY 121 Query: 127 VGRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDNGGAAD 186 +A+R+LVVD E Q+ R MQR+ + R+ VE I+AAQA+R+ARLAVA DV+DN GA D Sbjct: 122 -QKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQATREARLAVADDVIDNNGAPD 180 Query: 187 SLPERVRNLHSQYLALAAQ 205 ++ V LH+ YL LA+Q Sbjct: 181 AIASDVARLHASYLKLASQ 199 >RSc2828 [H] COG0237 Dephospho-CoA kinase Rso Ralstonia solanacearum Length = 204 Score = 187 bits (474), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 107/191 (56%), Positives = 129/191 (67%), Gaps = 9/191 (4%) Query: 9 TIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDARG 68 IGLTGGIGSGK+ VAE GAA+VDTDAIAH +TAP G AI ++E FG + A G Sbjct: 3 VIGLTGGIGSGKSYVAERLAERGAAVVDTDAIAHEITAPGGAAIPKLVEAFGPGILRADG 62 Query: 69 AMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASG----PYVIFVVPLLVES- 123 AMDR MR F + A+ LE I HPLIR +L A PY+++VVPLLVES Sbjct: 63 AMDRDAMRALAFSDATAKARLERITHPLIREISLSRGAAAQASDACPYLVYVVPLLVESL 122 Query: 124 ---GNWVGRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVD 180 +W DRILV+DCP E Q+ARV+ RNGL R VE+I+A QA+R+ARLAVA DV+D Sbjct: 123 SGHHSWRALVDRILVIDCPVETQIARVIARNGLPRALVESIVARQATREARLAVADDVID 182 Query: 181 NGGA-ADSLPE 190 NGGA AD LP+ Sbjct: 183 NGGALADLLPQ 193 >YPO3430 [H] COG0237 Dephospho-CoA kinase Ype Yersinia pestis Length = 206 Score = 169 bits (428), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 87/196 (44%), Positives = 123/196 (62%), Gaps = 1/196 (0%) Query: 8 FTIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDAR 67 + + LTGGIGSGK+TVA F LG LVD D IA + P A+A I +G + + Sbjct: 3 YIVALTGGIGSGKSTVANAFANLGVPLVDADIIARQVVEPGTSALAAIASRYGENILQQD 62 Query: 68 GAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVESGNWV 127 G+++R +RQ +F + + L ++LHPLI+ ET R PY ++VVPLLVE+G Sbjct: 63 GSLNRAALRQKIFSEQQEKAWLNSLLHPLIQQETQRQLAGIDQPYALWVVPLLVENG-LH 121 Query: 128 GRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDNGGAADS 187 RADR+LVVD ++Q+AR M R+G+ R + E I+A+Q SRQ RLA A D++DN G Sbjct: 122 HRADRVLVVDVTPDIQLARTMARDGITRQQAENILASQVSRQQRLACADDIIDNSGDPLM 181 Query: 188 LPERVRNLHSQYLALA 203 + + V +LH +YL LA Sbjct: 182 IAQHVASLHHRYLKLA 197 >PM0088 [H] COG0237 Dephospho-CoA kinase Pmu Pasteurella multocida Length = 206 Score = 163 bits (412), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 81/200 (40%), Positives = 121/200 (60%), Gaps = 5/200 (2%) Query: 8 FTIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDAR 67 + +GLTGGIGSGK+T+A LF ALG ++D D +A + ++ I+++FG + Sbjct: 3 YIVGLTGGIGSGKSTIAHLFMALGVPVIDADVVARDIVTKGSELLSKIVDYFGEHILCEN 62 Query: 68 GAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVESGNWV 127 G ++R ++R+ +F +PE + L +LHP IR E LR ++ + PYV++VVPLL+E+ N Sbjct: 63 GELNRAKLRERIFRHPEDKVWLNQLLHPAIREEMLRQLQIQTYPYVLWVVPLLIEN-NLT 121 Query: 128 GRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDN----GG 183 R+LVVD E Q+ R MQR+ + ++ IMA+Q RQ RL A DV+ N G Sbjct: 122 AFCQRVLVVDVEPETQIQRAMQRDNNSIELIQHIMASQVDRQTRLQFADDVIQNDADLKG 181 Query: 184 AADSLPERVRNLHSQYLALA 203 L ++V LH QYL LA Sbjct: 182 NLPVLKQKVLELHHQYLQLA 201 >HI0890m [H] COG0237 Dephospho-CoA kinase Hin Haemophilus influenzae Length = 206 Score = 157 bits (398), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 83/203 (40%), Positives = 120/203 (59%), Gaps = 5/203 (2%) Query: 8 FTIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDAR 67 + +GLTGGIGSGKTT+A LF LG LVD D +A + A D ++ I+EHFGA + + Sbjct: 3 YIVGLTGGIGSGKTTIANLFTDLGVPLVDADVVAREVVAKDSPLLSKIVEHFGAQILTEQ 62 Query: 68 GAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVESGNWV 127 G ++R +R+ VF + E + L +LHP IR + + PY +FVVPLL+E+ Sbjct: 63 GELNRAALRERVFNHDEDKLWLNNLLHPAIRERMKQKLAEQTAPYTLFVVPLLIENK-LT 121 Query: 128 GRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDNGGA-AD 186 DRILVVD + Q+AR QR+ ++++ IM +Q S+Q RL A DV++N A Sbjct: 122 ALCDRILVVDVSPQTQLARSAQRDNNNFEQIQRIMNSQVSQQERLKWADDVINNDAELAQ 181 Query: 187 SLP---ERVRNLHSQYLALAAQR 206 +LP ++V LH YL A + Sbjct: 182 NLPHLQQKVLELHQFYLQQAENK 204 >VC2427 [H] COG0237 Dephospho-CoA kinase Vch Vibrio cholerae Length = 213 Score = 156 bits (394), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 83/199 (41%), Positives = 117/199 (58%), Gaps = 2/199 (1%) Query: 8 FTIGLTGGIGSGKTTVAELF-GALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADFIDA 66 F + LTGGI SGKTTVA LF G LVD D IA + P+ + I HFG + Sbjct: 14 FVVALTGGIASGKTTVANLFHDQFGIDLVDADVIARDVVKPETEGLKAIAAHFGQAILHP 73 Query: 67 RGAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVESGNW 126 G+++R +R+ +F P + L +LHP+IR A + PY + +VPLLVE+ Sbjct: 74 DGSLNRAALRERIFAAPNEKAWLNQLLHPMIRQGMRNALTQTTSPYALLIVPLLVEN-QL 132 Query: 127 VGRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDNGGAAD 186 ADR+LVVD E++Q+ R M R+ + R++ EAI+AAQASR RLA+A DV+ N Sbjct: 133 QTMADRVLVVDVDEKIQIERTMARDKVSREQAEAILAAQASRAQRLAIADDVLKNDAENQ 192 Query: 187 SLPERVRNLHSQYLALAAQ 205 L ++ LH +YLA++ Q Sbjct: 193 KLLPQITLLHQKYLAMSRQ 211 >PA4529 [H] COG0237 Dephospho-CoA kinase Pae Pseudomonas aeruginosa Length = 203 Score = 152 bits (385), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 87/203 (42%), Positives = 117/203 (57%), Gaps = 1/203 (0%) Query: 4 LSERFTIGLTGGIGSGKTTVAELFGALGAALVDTDAIAHALTAPDGLAIAPIIEHFGADF 63 +++ + +GLTGGIGSGK+ AE F +LG LVD D A + P A+A I+E FG Sbjct: 1 MTQPWILGLTGGIGSGKSAAAEHFISLGVHLVDADHAARWVVEPGRPALAKIVERFGDGI 60 Query: 64 IDARGAMDRTRMRQHVFGNPEARHALEAILHPLIRSETLRAAEVASGPYVIFVVPLLVES 123 + G +DR +R+ +F PE R LE +LHPLI +E ++ A PY I V PLLVES Sbjct: 61 LLPDGQLDRAALRERIFQAPEERRWLEQLLHPLIGAEIVQYLARAESPYAILVSPLLVES 120 Query: 124 GNWVGRADRILVVDCPEEVQVARVMQRNGLRRDEVEAIMAAQASRQARLAVAADVVDNGG 183 G R+LVVD PE +Q+ R M R+ + ++V +I+ AQA R RL A DV+ N G Sbjct: 121 GQ-RQMTHRVLVVDTPEHLQLQRTMLRDKVSEEQVRSILQAQARRDERLKHADDVLVNDG 179 Query: 184 AADSLPERVRNLHSQYLALAAQR 206 L V LH+ YL L R Sbjct: 180 DLSHLQREVERLHAFYLTLRGGR 202