BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0090.p (174 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2784 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 159 3e-39 XF1990 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins X... 84 2e-16 NMB0006 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 83 3e-16 NMA0253 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 82 6e-16 FN2067 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins F... 77 3e-14 BH1522 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins B... 75 1e-13 DR0189 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins D... 74 1e-13 BS_yneN [OC] COG0526 Thiol-disulfide isomerase and thioredoxins ... 74 1e-13 TP0100 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins T... 72 5e-13 BH1577 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins B... 71 1e-12 >RSc2784 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Rso Ralstonia solanacearum Length = 174 Score = 159 bits (402), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 79/173 (45%), Positives = 106/173 (61%), Gaps = 1/173 (0%) Query: 2 MKKLRNVILLAVVAVVCVGIGLYASHRAHPADSAETQALNRLLAQSLPDATGQMQSLAQY 61 M + + +I L + +V +G+YA HRA A+ LPDA G L+ + Sbjct: 1 MSRRQTLIALILAGIVAAVLGVYAGHRATQPRPPADGAVTAFFDARLPDANGTPIDLSAF 60 Query: 62 RGKPLIVNFWATWCGPCVEEMPELTALQQE-IAPVQILGIGVDSQENIGKFAQKYQIRYP 120 RG+P+++NFWA WCGPCVEEMPEL+AL QE A V+ +GIG+DS NI F K + YP Sbjct: 61 RGQPVVINFWAPWCGPCVEEMPELSALAQEQKARVKFIGIGIDSAANIQAFLGKVPVTYP 120 Query: 121 LFVAGTGATDLLRQFGNQAGGLPFTALVGKDGNVKKIYLGRLKFDELRQDLSQ 173 + VAG G T+L RQ GNQAGGLPFT ++ G + +GR+ DELR L + Sbjct: 121 IAVAGFGGTELGRQLGNQAGGLPFTVILNAQGEITFRKMGRVHADELRAALQR 173 >XF1990 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Xfa Xylella fastidiosa 9a5c Length = 211 Score = 83.6 bits (205), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 43/114 (37%), Positives = 66/114 (57%), Gaps = 9/114 (7%) Query: 53 GQMQSLAQYRGKPLIVNFWATWCGPCVEEMPELTALQQEIAPVQILGIGVDSQ--ENIGK 110 G++ LA +RGK ++VN WATWC PC++EMPEL+AL + V+++G+ D E I Sbjct: 87 GEVYDLAAHRGKWVLVNVWATWCEPCLKEMPELSALHRRRRDVEVVGLAYDDSKPEEIRT 146 Query: 111 FAQKYQIRYPLFVAGTGATDLLRQFGNQAG--GLPFTALVGKDGNVKKIYLGRL 162 F + + + YP+ + D+ N A GLP + L+ DG V K +LG + Sbjct: 147 FLRSHPVVYPIIL-----VDISNPPKNFAAPRGLPMSYLIAPDGTVAKQFLGSI 195 >NMB0006 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Nme Neisseria meningitidis MC58 Length = 160 Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 46/131 (35%), Positives = 69/131 (52%), Gaps = 13/131 (9%) Query: 20 GIGLYASHRAHPADSAETQALNRLLAQSLPDATGQMQSLAQYRGKPLIVNFWATWCGPCV 79 I L A+ AH A + E QSL QSL + IVN WATWCGPC Sbjct: 8 AITLAATFAAHTASADELAGWKDNTPQSL-------QSL---KAPVRIVNLWATWCGPCR 57 Query: 80 EEMPELTAL--QQEIAPVQILGIGVDSQENIGKFAQKYQIRYPLF-VAGTGATDLLRQFG 136 +EMP ++ Q+ V ++GI +D+ +NIG F ++ + YP++ G + + ++ +G Sbjct: 58 KEMPAMSKWYKAQKKGSVDMVGIALDTSDNIGNFLKQTPVSYPIWRYTGANSRNFMKTYG 117 Query: 137 NQAGGLPFTAL 147 N G LPFT + Sbjct: 118 NTVGVLPFTVV 128 >NMA0253 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins NmA Neisseria meningitidis Z2491 Length = 160 Score = 82.0 bits (201), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 48/153 (31%), Positives = 74/153 (48%), Gaps = 13/153 (8%) Query: 20 GIGLYASHRAHPADSAETQALNRLLAQSLPDATGQMQSLAQYRGKPLIVNFWATWCGPCV 79 I L A+ AH A + E QSL QSL + IVN WATWCGPC Sbjct: 8 AITLAATFAAHTASADELAGWKDNTPQSL-------QSL---KAPVRIVNLWATWCGPCQ 57 Query: 80 EEMPELTAL--QQEIAPVQILGIGVDSQENIGKFAQKYQIRYPLF-VAGTGATDLLRQFG 136 +EMP ++ Q+ V ++GI +D+ +NIG F ++ + YP++ + + ++ +G Sbjct: 58 KEMPAMSKWYKAQKKGSVDMVGIALDTSDNIGNFLKQTPVSYPIWRYTEANSRNFMKSYG 117 Query: 137 NQAGGLPFTALVGKDGNVKKIYLGRLKFDELRQ 169 N G LPFT + K+ G + L + Sbjct: 118 NNVGVLPFTVVEAPKCGYKQTITGEVNEKSLTE 150 >FN2067 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Fnu Fusobacterium nucleatum Length = 164 Score = 76.6 bits (187), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 21/142 (14%) Query: 48 LPDATGQMQSLAQYRGKPLIVNFWATWCGPCVEEMPELTALQQEIAP----VQILGI-GV 102 L D G+ ++ +Y+GK +++NFWATWCG CVEEMP + +E V ILG+ G Sbjct: 23 LYDQYGKKHNIEEYKGKVVVINFWATWCGYCVEEMPGFEKVYKEFGSNKKDVIILGVAGP 82 Query: 103 DSQENIGK----------FAQKYQIRYPLFVAGTGATDLLRQFGN-QAGGLPFTALVGKD 151 S+EN+ F +K I YP + TG + F + + LP T ++ K+ Sbjct: 83 KSKENLNNVDVEKDKIISFLKKKNITYPSLMDETG-----KSFDDYKVRALPMTYVINKN 137 Query: 152 GNVKKIYLGRLKFDELRQDLSQ 173 G ++ G + ++LR+ +++ Sbjct: 138 GYLEGFVNGAITDEQLRKAINE 159 >BH1522 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bha Bacillus halodurans Length = 177 Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 40/125 (32%), Positives = 69/125 (55%), Gaps = 14/125 (11%) Query: 53 GQMQSLAQYRGKPLIVNFWATWCGPCVEEMPELTALQQ--EIAPVQILGIGVDSQE---- 106 Q +SL+ YRG +I+N WA+WC PC +EMP L LQ E V I+ + + + E Sbjct: 49 SQSRSLSDYRGDVVILNVWASWCEPCRKEMPALMELQSDYESEDVSIVTVNMQTFERTVN 108 Query: 107 NIGKFAQKYQIRYPLFVAGTGATDLLRQFGN--QAGGLPFTALVGKDGNVKKIYLGRLKF 164 + G+F ++ I P+F+ G +F + Q LP T ++ ++G + ++ LG + + Sbjct: 109 DAGEFIEELGITLPVFLDEEG------EFADAYQVQHLPMTYVLDREGIINEVILGEVTY 162 Query: 165 DELRQ 169 ++L Q Sbjct: 163 EQLEQ 167 >DR0189 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Dra Deinococcus radiodurans Length = 185 Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 44/124 (35%), Positives = 62/124 (50%), Gaps = 6/124 (4%) Query: 53 GQMQSLAQYRGKPLIVNFWATWCGPCVEEMPELTALQQEIAPVQILGIGVDSQ--ENIGK 110 GQ +LA YRG+P+++NFWA+WCGPC EE P L +LGI + +N Sbjct: 61 GQPVALADYRGRPVVLNFWASWCGPCREEAPLFAKLAAHPGAPAVLGILFNETKPQNARD 120 Query: 111 FAQKYQIRYPLFVAGTGATDLLRQFGNQAGGLPFTALVGKDGNVKKIYLGRLKFDELRQD 170 FA++Y + YP AT + Q G+P T + G V+ I G L L Sbjct: 121 FARQYGLTYPNLQDPGVATAIAYQV----TGIPRTVFIDAQGVVRHIDQGGLDTARLNAG 176 Query: 171 LSQL 174 LS++ Sbjct: 177 LSKI 180 >BS_yneN [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bsu Bacillus subtilis Length = 170 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 15/177 (8%) Query: 1 LMKKLRNVILLAVVAVVCVGIGLYASHRAHPADSAETQALNRLLAQSLPDATGQMQSLAQ 60 L K L ++L+ +V G LY ++ E Q SL +G+ SL Sbjct: 2 LKKWLAGILLIMLVGYT--GWNLYQTYSKKEVGIQEGQQAPDF---SLKTLSGEKSSLQD 56 Query: 61 YRGKPLIVNFWATWCGPCVEEMPELTALQQEIA-PVQILGIGVDSQENIGK----FAQKY 115 +GK +++NFWATWC PC +EMP + LQ+E A + ++ + S E K FA Y Sbjct: 57 AKGKKVLLNFWATWCKPCRQEMPAMEKLQKEYADKLAVVAVNFTSAEKSEKQVRAFADTY 116 Query: 116 QIRYPLFVAGTGATDLLRQFGNQAGGLPFTALVGKDGNVKKIYLGRLKFDELRQDLS 172 + +P+ + G P T ++ + G ++ I++G + E+ Q L Sbjct: 117 DLTFPILIDKKGIN-----ADYNVMSYPTTYILDEKGVIQDIHVGTMTKKEMEQKLD 168 >TP0100 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Tpa Treponema pallidum Length = 200 Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 54/179 (30%), Positives = 90/179 (50%), Gaps = 25/179 (13%) Query: 5 LRNVILLAVVAVVCVGIGLYASHRAHPAD--SAETQALNRLLAQSLP---DATGQMQSLA 59 R+V++LAV V CV A+ AH AD S +AL R P D + + A Sbjct: 17 FRSVLVLAVWGVSCV----QAADVAHNADVPSRSLKALERFRFFVYPKPLDLSSDFHAKA 72 Query: 60 Q---------YRGKPLIVNFWATWCGPCVEEMPELTALQQEIA--PVQILGIGV-DSQEN 107 ++GK ++NFWATWC PC EMP + +Q + QI+ + V DS++ Sbjct: 73 LKGEALVPSLFKGKVTLLNFWATWCPPCRAEMPSMDRMQALMRGNDFQIVAVNVGDSRKQ 132 Query: 108 IGKFAQKYQIRYPLFVAGTGATDLLRQFGNQAGGLPFTALVGKDGNVKKIYLGRLKFDE 166 + F + + +P+++ G+ L F ++ GLP T +V K G + + +G +++D+ Sbjct: 133 VESFIARGKHTFPIYLDEEGS--LGSVFASR--GLPTTYVVDKAGRIVAVVVGSVEYDQ 187 >BH1577 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins Bha Bacillus halodurans Length = 176 Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 43/161 (26%), Positives = 82/161 (50%), Gaps = 8/161 (4%) Query: 3 KKLRNVILLAVVAVVCVGIGLYASHRAHPADSAETQALNRLLAQSLPDATGQMQSLAQYR 62 K+ R + L+++AV+ V +G Y + AD + +A + + L D G+ L + Sbjct: 3 KRKRFWMRLSILAVISVALG-YTFYSNFFADRSLARAGEQAVNFVLEDLEGESIELRELE 61 Query: 63 GKPLIVNFWATWCGPCVEEMPELTALQQEIAP--VQILGIGVDSQE-NIGKFAQKYQIRY 119 GK + +NFW T+C PC EMP + L E V+I+ + + E + +F +Y + + Sbjct: 62 GKGVFLNFWGTYCPPCEREMPHMEKLYGEYKEQGVEIIAVNANEPELTVQRFVDRYGLSF 121 Query: 120 PLFVAGTGATDLLRQFGNQAGGLPFTALVGKDGNVKKIYLG 160 P+ + +++ +G + LP T L+ + G + K++ G Sbjct: 122 PIVI--DKGLNVIDAYGIRP--LPTTILINEHGEIVKVHTG 158