BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0049.p (637 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4973 [H] COG0422 Thiamine biosynthesis protein ThiC Pae Pseudo... 1026 0.0 NMB2040 [H] COG0422 Thiamine biosynthesis protein ThiC Nme Neiss... 931 0.0 RSc0113 [H] COG0422 Thiamine biosynthesis protein ThiC Rso Ralst... 931 0.0 NMA0397 [H] COG0422 Thiamine biosynthesis protein ThiC NmA Neiss... 930 0.0 STM4164 [H] COG0422 Thiamine biosynthesis protein ThiC Sty Salmo... 924 0.0 thiC [H] COG0422 Thiamine biosynthesis protein ThiC Eco Escheric... 917 0.0 ECs4917 [H] COG0422 Thiamine biosynthesis protein ThiC Ecs Esche... 917 0.0 ZthiC [H] COG0422 Thiamine biosynthesis protein ThiC EcZ Escheri... 912 0.0 YPO3739 [H] COG0422 Thiamine biosynthesis protein ThiC Ype Yersi... 903 0.0 BS_thiA [H] COG0422 Thiamine biosynthesis protein ThiC Bsu Bacil... 893 0.0 >PA4973 [H] COG0422 Thiamine biosynthesis protein ThiC Pae Pseudomonas aeruginosa Length = 627 Score = 1026 bits (2653), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/624 (79%), Positives = 540/624 (86%), Gaps = 13/624 (2%) Query: 14 VDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIYVYDTSGPYTDP 73 +D + QP PNSRK+Y+TGSRPDIRVP+REIS ADTP FG EKNPP++VYDTSGPYTDP Sbjct: 15 LDRQSTQPFPNSRKVYLTGSRPDIRVPVREISLADTPTAFGGEKNPPVFVYDTSGPYTDP 74 Query: 74 EVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHRKPRRAKA 133 EV+ID+R GL R WI ER DTE LPG TSE+GQ RL D +L LRF R PRRAK Sbjct: 75 EVRIDLRKGLPDVRSRWIDERGDTEILPGLTSEFGQARLADASLDALRFAHVRTPRRAKP 134 Query: 134 GANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGRQHPGQSF 193 GANV+QMHYA++GIITPEME+IAIREN++ L++ +A+G L+ +QHPG SF Sbjct: 135 GANVSQMHYAKKGIITPEMEYIAIRENMK----LQEARAAG--------LLDQQHPGHSF 182 Query: 194 GASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVTSSIG 253 GA+IP EITPEFVR+EVARGRAIIPANINH E+EPMIIGRNFLVKIN NIGNSA+ SSI Sbjct: 183 GANIPKEITPEFVREEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIE 242 Query: 254 EEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDL 313 EEVEK+TW IRWG D VMDLSTGK+IHETREWI+RNSPVPIGTVPIYQALEKVNG AEDL Sbjct: 243 EEVEKLTWGIRWGADTVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDL 302 Query: 314 TWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWCLAHHRES 373 TWEIFRDTLIEQAEQGVDYFTIHAGV L+YVPLTAKR+TGIVSRGGSIMAKWCLAHH+E+ Sbjct: 303 TWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQEN 362 Query: 374 FLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIAWKHDVQV 433 FLY HFEEICEIMKAYDVSFSLGDGLRPGS+ DAND AQ GEL TLGELT+IAWKHDVQV Sbjct: 363 FLYTHFEEICEIMKAYDVSFSLGDGLRPGSVADANDAAQFGELETLGELTKIAWKHDVQV 422 Query: 434 MIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGT 493 MIEGPGHVPM LIKENMD QLE C EAPFYTLGPLTTDIAPGYDHITSGIGAA IGW+G Sbjct: 423 MIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGC 482 Query: 494 AMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWE 553 AMLCYVTPKEHLGLPNK DVK GIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWE Sbjct: 483 AMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWE 542 Query: 554 DQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAKEGIS-EI 612 DQFN+GLDPD AR FHDETLPKDSAKVAHFCSMCGP FCSMKITQEVRDYA + G+S E Sbjct: 543 DQFNLGLDPDTARAFHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKENGLSDES 602 Query: 613 DALKQGMQVKSVEFVKMGAEIYSK 636 A++ G Q ++ F G+ IY + Sbjct: 603 KAIEAGFQEQAARFKDEGSVIYRQ 626 >NMB2040 [H] COG0422 Thiamine biosynthesis protein ThiC Nme Neisseria meningitidis MC58 Length = 633 Score = 931 bits (2405), Expect = 0.0, Method: Compositional matrix adjust. Identities = 449/616 (72%), Positives = 507/616 (82%), Gaps = 17/616 (2%) Query: 23 PNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIYVYDTSGPYTDPEVKIDIRAG 82 PNS ++Y+ GSR DIRVP+REI Q DT G+E NPPI VYDTSG Y DP ID++ G Sbjct: 32 PNSERVYLQGSRDDIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGVYGDPAAHIDLKQG 91 Query: 83 LSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHRKPRRAKAGANVTQMHY 142 L R W+ ER DTE LP +SEYG +R +DP A LRFN +PRRAK+G+NVTQ+HY Sbjct: 92 LPHIRTAWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKSGSNVTQLHY 151 Query: 143 ARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGRQHPGQSFGASIPA--- 199 AR+GIITPEMEF+AIRE L+ E ++ P KL + QH GQSFGA+IP Sbjct: 152 ARQGIITPEMEFVAIRERLKLDELSQK-----PEYAKLLE----QHAGQSFGANIPTHPD 202 Query: 200 EITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVTSSIGEEVEKM 259 +ITPEFVR E+A GRAIIPANINHPE+EPMIIGRNF VKIN N+GNSAVTSS+ EEVEKM Sbjct: 203 QITPEFVRQEIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKM 262 Query: 260 TWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFR 319 W++RWG D +MDLSTG +IHETREWIIRN+PVPIGTVPIYQALEK G AEDLTW++FR Sbjct: 263 VWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDLFR 322 Query: 320 DTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWCLAHHRESFLYEHF 379 DTLIEQAEQGVDYFTIHAGV L+YVP+TA R+TGIVSRGGSIMAKWCLAHHRE+FLY HF Sbjct: 323 DTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHF 382 Query: 380 EEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIAWKHDVQVMIEGPG 439 +EICEIMKAYDVSFSLGDGLRPG I DANDE+Q EL TLGELT AWKHDVQVMIEGPG Sbjct: 383 DEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPG 442 Query: 440 HVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYV 499 HVP+ +KENM +L+ C EAPFYTLGPL TDIAPGYDHITSGIGAA IGWYGTAMLCYV Sbjct: 443 HVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYV 502 Query: 500 TPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNIG 559 TPKEHLGLP+K DV+ GIITYK+AAHAADLAKG PGAQ+RDNALSKARFEFRW DQF + Sbjct: 503 TPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLS 562 Query: 560 LDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAKEGISEIDALKQGM 619 LDP++A FHDETLP + AK+AHFCSMCGP FCSMKITQEVRDYA K+ A +QGM Sbjct: 563 LDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQ-----KAQRQGM 617 Query: 620 QVKSVEFVKMGAEIYS 635 + K+VEFVK GA+IYS Sbjct: 618 EEKAVEFVKKGAKIYS 633 >RSc0113 [H] COG0422 Thiamine biosynthesis protein ThiC Rso Ralstonia solanacearum Length = 631 Score = 931 bits (2405), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/616 (73%), Positives = 509/616 (82%), Gaps = 13/616 (2%) Query: 23 PNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIYVYDTSGPYTDPEVKIDIRAG 82 P S K Y+ GSRPD+RVPMR I Q T G NPPI VYDTSGPY+DP+V ID++AG Sbjct: 26 PASSKTYIAGSRPDLRVPMRTIKQTATRTDQGEMLNPPIPVYDTSGPYSDPDVHIDLKAG 85 Query: 83 LSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHRKPRRAKAGANVTQMHY 142 L+ R WI ER DT LP +SEYGQ R +DPA A LRF PRRAK GANV+QMHY Sbjct: 86 LAPLRAKWIDERGDTVVLPSLSSEYGQARAHDPATAHLRFAQLTNPRRAKPGANVSQMHY 145 Query: 143 ARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGRQHPGQSFGASIPA--- 199 ARRGIITPEME++A+RE+L L+ L+ P KL +QHPG S+GA++P Sbjct: 146 ARRGIITPEMEYVALRESLN----LQALQ-DKPEYRKLL----KQHPGFSYGANLPQRPE 196 Query: 200 EITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVTSSIGEEVEKM 259 +ITPEFVR E+A GRAIIPANINH E+EPM IGRNF VKIN N+GNSAVTSS+ EEVEKM Sbjct: 197 DITPEFVRQEIAAGRAIIPANINHVELEPMAIGRNFRVKINGNLGNSAVTSSLAEEVEKM 256 Query: 260 TWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFR 319 W+IRWG D +MDLSTGK+IHETREWI+RNSPVPIGTVPIYQAL+K G AEDLTWE+FR Sbjct: 257 VWSIRWGADTIMDLSTGKHIHETREWILRNSPVPIGTVPIYQALDKTGGVAEDLTWEMFR 316 Query: 320 DTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWCLAHHRESFLYEHF 379 DTLIEQAEQGVDYFTIHAGV L+YVPLTA R+TGIVSRGGSIMAKWCLAHH+E+FLY HF Sbjct: 317 DTLIEQAEQGVDYFTIHAGVLLRYVPLTADRITGIVSRGGSIMAKWCLAHHKENFLYTHF 376 Query: 380 EEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIAWKHDVQVMIEGPG 439 +EICEIMKAYDVSFSLGDGLRPG I D+ND AQ GEL TLGELT+ AW+HDVQVMIEGPG Sbjct: 377 DEICEIMKAYDVSFSLGDGLRPGCIADSNDAAQFGELYTLGELTKKAWEHDVQVMIEGPG 436 Query: 440 HVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYV 499 HVP+ ++ NMD +L+ C EAPFYTLGPL TDIAPGYDHITSGIGAA IGWYGTAMLCYV Sbjct: 437 HVPLQRVQANMDEELKHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYV 496 Query: 500 TPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNIG 559 TPKEHLGLP+K DV++GIITYKIAAHAADLAKG PGAQ+RDNALSKARFEFRWEDQFN+G Sbjct: 497 TPKEHLGLPDKEDVREGIITYKIAAHAADLAKGWPGAQLRDNALSKARFEFRWEDQFNLG 556 Query: 560 LDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAKEGISEIDALKQGM 619 LDP+KAR FHDETLP + AK+AHFCSMCGP FCSMKITQEVRDYAA + A + GM Sbjct: 557 LDPEKARAFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYAASLD-ANATAAEHGM 615 Query: 620 QVKSVEFVKMGAEIYS 635 + KS+EF K GA+IYS Sbjct: 616 EEKSIEFRKAGAKIYS 631 >NMA0397 [H] COG0422 Thiamine biosynthesis protein ThiC NmA Neisseria meningitidis Z2491 Length = 633 Score = 930 bits (2403), Expect = 0.0, Method: Compositional matrix adjust. Identities = 450/616 (73%), Positives = 506/616 (82%), Gaps = 17/616 (2%) Query: 23 PNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIYVYDTSGPYTDPEVKIDIRAG 82 PNS ++Y+ GSR DIRVP+REI Q DT G+E NPPI VYDTSG Y DP ID++ G Sbjct: 32 PNSERVYLQGSRDDIRVPLREIRQDDTYTAQGAEANPPIPVYDTSGVYGDPAAHIDLKQG 91 Query: 83 LSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHRKPRRAKAGANVTQMHY 142 L R W+ ER DTE LP +SEYG +R +DP A LRFN +PRRAKAG NVTQ+HY Sbjct: 92 LPHIRTVWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHY 151 Query: 143 ARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGRQHPGQSFGASIPA--- 199 AR+GIITPEMEF+AIRE L+ E ++ P KL +QH GQSFGA+IP Sbjct: 152 ARQGIITPEMEFVAIRERLKLDELSQK-----PEYAKLL----KQHAGQSFGANIPTHPD 202 Query: 200 EITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVTSSIGEEVEKM 259 +ITPEFVR E+A GRAIIPANINHPE+EPMIIGRNF VKIN N+GNSAVTSS+ EEVEKM Sbjct: 203 QITPEFVRREIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKM 262 Query: 260 TWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFR 319 W++RWG D +MDLSTG +IHETREWIIRN+PVPIGTVPIYQALEK G AEDLTW++FR Sbjct: 263 VWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDLFR 322 Query: 320 DTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWCLAHHRESFLYEHF 379 DTLIEQAEQGVDYFTIHAGV L+YVP+TA R+TGIVSRGGSIMAKWCLAHHRE+FLY HF Sbjct: 323 DTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHF 382 Query: 380 EEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIAWKHDVQVMIEGPG 439 +EICEIMKAYDVSFSLGDGLRPG I DANDE+Q EL TLGELT AWKHDVQVMIEGPG Sbjct: 383 DEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPG 442 Query: 440 HVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYV 499 HVP+ +KENM +L+ C EAPFYTLGPL TDIAPGYDHITSGIGAA IGWYGTAMLCYV Sbjct: 443 HVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYV 502 Query: 500 TPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNIG 559 TPKEHLGLP+K DV+ GIITYK+AAHAADLAKG PGAQ+RDNALSKARFEFRW DQF + Sbjct: 503 TPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLS 562 Query: 560 LDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAKEGISEIDALKQGM 619 LDP++A FHDETLP + AK+AHFCSMCGP FCSMKITQEVRDYA K+ A +QGM Sbjct: 563 LDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQ-----KAQRQGM 617 Query: 620 QVKSVEFVKMGAEIYS 635 + K+VEFVK GA+IYS Sbjct: 618 EEKAVEFVKKGAKIYS 633 >STM4164 [H] COG0422 Thiamine biosynthesis protein ThiC Sty Salmonella typhimurium LT2 Length = 631 Score = 924 bits (2387), Expect = 0.0, Method: Compositional matrix adjust. Identities = 449/631 (71%), Positives = 511/631 (80%), Gaps = 28/631 (4%) Query: 14 VDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIY-------VYDT 66 +D PNS++IYVTGS+ DIRVPMREI +P + G K+ P + VYDT Sbjct: 19 IDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQL--SPTLIGGSKDNPQFEENEAVPVYDT 76 Query: 67 SGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHR 126 SGPY DPEV I+++ GL+ R PWI R+D+EEL +S Y ++RL D L +LRF Sbjct: 77 SGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLL 136 Query: 127 KPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGR 186 P+RAKAG VTQ+HYAR+GI+TPEMEFIAIREN+ R E++++ +++ Sbjct: 137 TPKRAKAGKRVTQLHYARKGIVTPEMEFIAIRENMGR----ERIRS---------EVLRH 183 Query: 187 QHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNS 246 QHPG +FGA +P ITPEFVRDEVA GRAIIPANINHPE EPMIIGRNFLVK+NANIGNS Sbjct: 184 QHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNS 243 Query: 247 AVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKV 306 AVTSSI EEVEK+ W+ RWG D VMDLSTG+ IHETREWI+RNSPVPIGTVPIYQALEKV Sbjct: 244 AVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKV 303 Query: 307 NGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWC 366 NG AEDLTWE FRDTL+EQAEQGVDYFTIHAGV L+YVP+TAKR+TGIVSRGGSIMAKWC Sbjct: 304 NGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWC 363 Query: 367 LAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIA 426 L+HH+E+FL+EHF EICEI AYDVS SLGDGLRPGSI DANDEAQ EL TLGELT+IA Sbjct: 364 LSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIA 423 Query: 427 WKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAA 486 W++DVQVMIEGPGHVPMH+I+ NM +LE CHEAPFYTLGPLTTDIAPGYDH TSGIGAA Sbjct: 424 WEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAA 483 Query: 487 QIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKA 546 IGW+G AMLCYVTPKEHLGLPNK DVK G+ITYKIAAHAADLAKGHPGAQIRDNA+SKA Sbjct: 484 MIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKA 543 Query: 547 RFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAK 606 RFEFRWEDQFN+ LDP AR +HDETLP++S KVAHFCSMCGP FCSMKI+QEVRDYAA Sbjct: 544 RFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAA 603 Query: 607 EGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 + I EI GM S +F G EIY K+ Sbjct: 604 QTI-EI-----GMADMSEDFRAKGGEIYLKR 628 >thiC [H] COG0422 Thiamine biosynthesis protein ThiC Eco Escherichia coli K12 Length = 631 Score = 917 bits (2370), Expect = 0.0, Method: Compositional matrix adjust. Identities = 444/631 (70%), Positives = 505/631 (80%), Gaps = 28/631 (4%) Query: 14 VDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIY-------VYDT 66 +D PNS++IY+TG+ P +RVPMREI +P + G K P Y VYDT Sbjct: 19 IDTLEGTAFPNSKRIYITGTHPGVRVPMREIQL--SPTLIGGSKEQPQYEENEAIPVYDT 76 Query: 67 SGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHR 126 SGPY DP++ I+++ GL+ R PWI R DTEEL +S+Y + RL D L ELRF+ Sbjct: 77 SGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVL 136 Query: 127 KPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGR 186 P+RAKAG VTQ+HYAR+GIITPEMEFIAIREN+ R E++++ +++ Sbjct: 137 TPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGR----ERIRS---------EVLRH 183 Query: 187 QHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNS 246 QHPG SFGA +P IT EFVRDEVA GRAIIPANINHPE EPMIIGRNFLVK+NANIGNS Sbjct: 184 QHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNS 243 Query: 247 AVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKV 306 AVTSSI EEVEK+ W+ RWG D VMDLSTG+ IHETREWI+RNSPVPIGTVPIYQALEKV Sbjct: 244 AVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKV 303 Query: 307 NGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWC 366 NG AEDLTWE FRDTL+EQAEQGVDYFTIHAGV L+YVP+TAKR+TGIVSRGGSIMAKWC Sbjct: 304 NGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWC 363 Query: 367 LAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIA 426 L+HH+E+FLY+HF EICEI AYDVS SLGDGLRPGSI DANDEAQ EL TLGELT+IA Sbjct: 364 LSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIA 423 Query: 427 WKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAA 486 W++DVQVMIEGPGHVPM +I+ NM +LE CHEAPFYTLGPLTTDIAPGYDH TSGIGAA Sbjct: 424 WEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAA 483 Query: 487 QIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKA 546 IGW+G AMLCYVTPKEHLGLPNK DVK G+ITYKIAAHAADLAKGHPGAQIRDNA+SKA Sbjct: 484 MIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKA 543 Query: 547 RFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAK 606 RFEFRWEDQFN+ LDP AR +HDETLP++S KVAHFCSMCGP FCSMKI+QEVRDYAA Sbjct: 544 RFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAT 603 Query: 607 EGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 + I + GM S F G EIY ++ Sbjct: 604 QTI------EMGMADMSENFRARGGEIYLRK 628 >ECs4917 [H] COG0422 Thiamine biosynthesis protein ThiC Ecs Escherichia coli O157:H7 Length = 631 Score = 917 bits (2369), Expect = 0.0, Method: Compositional matrix adjust. Identities = 443/631 (70%), Positives = 506/631 (80%), Gaps = 28/631 (4%) Query: 14 VDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIY-------VYDT 66 +D PNS++IY+TG++P +RVPMREI +P + G K P Y VYDT Sbjct: 19 IDTLEGTAFPNSKRIYITGTQPGVRVPMREIQL--SPTLIGGSKEQPQYEENEAIPVYDT 76 Query: 67 SGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHR 126 SGPY DP++ I+++ GL+ R PWI R DTEEL +S+Y + RL D L ELRF+ Sbjct: 77 SGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVL 136 Query: 127 KPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGR 186 P+RAKAG VTQ+HYAR+GIITPEMEFIAIREN+ R E++++ +++ Sbjct: 137 TPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGR----ERIRS---------EVLRH 183 Query: 187 QHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNS 246 QHPG SFGA +P IT EFVRDEVA GRAIIPANINHPE EPMIIGRNFLVK+NANIGNS Sbjct: 184 QHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNS 243 Query: 247 AVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKV 306 AVTSSI EEVEK+ W+ RWG D VMDLSTG+ IHETREWI+RNSPVPIGTVPIYQALEKV Sbjct: 244 AVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKV 303 Query: 307 NGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWC 366 NG AEDLTWE FRDTL+EQAEQGVDYFTIHAGV L+YVP+TAKR+TGIVSRGGSIMAKWC Sbjct: 304 NGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWC 363 Query: 367 LAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIA 426 L+HH+E+FLY+HF EICEI AYDVS SLGDGLRPGSI DANDEAQ EL TLGELT+IA Sbjct: 364 LSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIA 423 Query: 427 WKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAA 486 W++DVQVMIEGPGHVPM +I+ NM +LE CHEAPFYTLGPLTTDIAPGYDH TSGIGAA Sbjct: 424 WEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAA 483 Query: 487 QIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKA 546 IGW+G AMLCYVTPKEHLGLPNK DVK G+ITYKIAAHAADLAKGHPGAQIRDNA+SKA Sbjct: 484 MIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKA 543 Query: 547 RFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAK 606 RFEFRWEDQFN+ LDP AR +HDETLP++S KVAHFCSMCGP FCSMKI+QEVRDYAA Sbjct: 544 RFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAT 603 Query: 607 EGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 + I + G+ S F G EIY ++ Sbjct: 604 QTI------EMGIADMSENFRARGGEIYLRK 628 >ZthiC [H] COG0422 Thiamine biosynthesis protein ThiC EcZ Escherichia coli O157:H7 EDL933 Length = 631 Score = 912 bits (2358), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/631 (70%), Positives = 505/631 (80%), Gaps = 28/631 (4%) Query: 14 VDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIY-------VYDT 66 +D PNS++IY+TG++P +RVPMREI +P + G K P Y VYDT Sbjct: 19 IDTLEGTAFPNSKRIYITGTQPGVRVPMREIQL--SPTLIGGSKEQPQYEENEAIPVYDT 76 Query: 67 SGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHR 126 SGPY DP++ I+++ GL+ R PWI R DTEEL +S+Y + RL D L ELRF+ Sbjct: 77 SGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVL 136 Query: 127 KPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGR 186 P+RAKAG VTQ+HYAR+GIITPEMEFIAIREN+ R E++++ +++ Sbjct: 137 TPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGR----ERIRS---------EVLRH 183 Query: 187 QHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNS 246 QHPG SFGA +P IT EFVRDEVA GRAIIPANINHPE EPMIIGRNFLVK+NANIGNS Sbjct: 184 QHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNS 243 Query: 247 AVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKV 306 AVTSSI EEVEK+ W+ RWG D VMDLSTG+ IHETREWI+RNSPVPIGTVPIYQALEKV Sbjct: 244 AVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKV 303 Query: 307 NGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWC 366 NG AEDLTWE FRDTL+EQAEQGVDYFTIHAGV L+YVP+TAKR+TGIVSRGGSIMAKWC Sbjct: 304 NGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWC 363 Query: 367 LAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIA 426 L+HH+E+FLY+HF EICEI AYDVS SLGDGLRPGSI DANDEAQ EL TLGELT+IA Sbjct: 364 LSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIA 423 Query: 427 WKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAA 486 W++DVQVMIEGPGHVPM +I+ NM +LE CHEAPFYTLGPLTTDIAPGYDH TSGIGAA Sbjct: 424 WEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAA 483 Query: 487 QIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKA 546 IGW+G AMLCYVTPKEHLGLPNK DVK G+ITYKIAAHAADLAKGHPGAQIRDNA+SKA Sbjct: 484 MIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKA 543 Query: 547 RFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAK 606 RFEFRWEDQFN+ LDP AR +HDETLP++S KVAH CSMCGP FCSMKI+QEVRDYAA Sbjct: 544 RFEFRWEDQFNLALDPFTARAYHDETLPQESXKVAHXCSMCGPKFCSMKISQEVRDYAAX 603 Query: 607 EGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 + I + G+ S F G EIY ++ Sbjct: 604 QTI------EMGIXDMSENFRAXGGEIYLRK 628 >YPO3739 [H] COG0422 Thiamine biosynthesis protein ThiC Ype Yersinia pestis Length = 681 Score = 903 bits (2333), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/642 (68%), Positives = 503/642 (78%), Gaps = 42/642 (6%) Query: 22 LPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIY-------VYDTSGPYTDPE 74 PNS++IY+ GSRPDI+VPMREI +P G KN P Y VYDTSGPY DP+ Sbjct: 42 FPNSQRIYLQGSRPDIQVPMREIQL--SPTQIGGSKNEPRYEDNEAIPVYDTSGPYGDPQ 99 Query: 75 VKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFNLHRKPRRAKAG 134 K+D+ GL R W+ +R DTE L +S + QQRL D L LRF +PR+A G Sbjct: 100 AKLDVHNGLPKLRAAWVADRQDTEALASVSSGFTQQRLADEGLDHLRFEHLPRPRKAATG 159 Query: 135 ANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGRQHPGQSFG 194 VTQ+HYAR+G ITPEMEFIA+REN+ R E+++ +++ +QHPGQ+FG Sbjct: 160 QCVTQLHYARQGKITPEMEFIALRENMGR----ERIRG---------EVLLQQHPGQAFG 206 Query: 195 ASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVTSSIGE 254 A +P IT EFVR EVA GRAIIPANINHPE EPMIIGRNFLVK+NANIGNSAVTSSI E Sbjct: 207 AHLPENITAEFVRQEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEE 266 Query: 255 EVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLT 314 EVEK+ W+ RWG D VMDLSTG+ IHETREWI+RNSPVPIGTVPIYQALEKVNG AE+LT Sbjct: 267 EVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGVAENLT 326 Query: 315 WEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWCLAHHRESF 374 WE+FRDTL+EQAEQGVDYFT+HAGV L+YVP+TAKR+TGIVSRGGSIMAKWCL+HH+E+F Sbjct: 327 WEMFRDTLLEQAEQGVDYFTLHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENF 386 Query: 375 LYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIAWKHDVQVM 434 LY+HF EIC+I AYDVS SLGDGLRPGSI DANDEAQ EL TLGELT+IAW++DVQVM Sbjct: 387 LYQHFREICQICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVM 446 Query: 435 IEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTA 494 IEGPGHVPM +I+ NM +LE CHEAPFYTLGPLTTDIAPGYDH TSGIGAA IGW+G A Sbjct: 447 IEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCA 506 Query: 495 MLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWED 554 MLCYVTPKEHLGLPNK DVK G+ITYKIAAHAADLAKGHPGAQIRDNA+SKARFEFRWED Sbjct: 507 MLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWED 566 Query: 555 QFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAKEGISE--- 611 QFN+ LDP AR +HDETLP++S KVAHFCSMCGP FCSMKI+QEVRDYAA + + Sbjct: 567 QFNLALDPATARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQEQAAAQA 626 Query: 612 -----------------IDALKQGMQVKSVEFVKMGAEIYSK 636 I+ L+ GM+ S EF G+E+Y + Sbjct: 627 QAATPTTAAQPIDITQPINMLQSGMEKMSAEFRSRGSELYHR 668 >BS_thiA [H] COG0422 Thiamine biosynthesis protein ThiC Bsu Bacillus subtilis Length = 590 Score = 893 bits (2307), Expect = 0.0, Method: Compositional matrix adjust. Identities = 433/615 (70%), Positives = 487/615 (79%), Gaps = 50/615 (8%) Query: 25 SRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIYVYDTSGPYTDPEVKIDIRAGLS 84 S+K+YV GS DI+VPMREI+ + T FG E+N P+ VYDTSGPYTDPEV I+I+ GL Sbjct: 20 SKKVYVEGSSSDIQVPMREIALSPTTGSFGEEENAPVRVYDTSGPYTDPEVTINIQEGLK 79 Query: 85 TPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFN-----LHRKPRRAKAGANVTQ 139 R WI ER D EE G + D + + N L RKP RAKAG NVTQ Sbjct: 80 PLRQIWITERGDVEEYEGRAI-----KPEDNGYKKAKPNVSYPGLKRKPLRAKAGQNVTQ 134 Query: 140 MHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADLMGRQHPGQSFGASIPA 199 MHYA++GIITPEMEFIAIRE+ Sbjct: 135 MHYAKKGIITPEMEFIAIREH--------------------------------------- 155 Query: 200 EITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANIGNSAVTSSIGEEVEKM 259 ++PEFVRDEVA GRAIIP+NINHPE EPMIIGRNF VKINANIGNSAVTSSI EEVEKM Sbjct: 156 -VSPEFVRDEVASGRAIIPSNINHPESEPMIIGRNFHVKINANIGNSAVTSSIEEEVEKM 214 Query: 260 TWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFR 319 TWAIRWG D +MDLSTGK+IH TREWIIRN PVP+GTVPIYQALEKVNG AEDLTWEI+R Sbjct: 215 TWAIRWGADTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGVAEDLTWEIYR 274 Query: 320 DTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMAKWCLAHHRESFLYEHF 379 DTLIEQAEQGVDYFTIHAGV L+YVPLTAKR TGIVSRGG+IMA+WCLAHH+ESFLY HF Sbjct: 275 DTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRTTGIVSRGGAIMAQWCLAHHQESFLYTHF 334 Query: 380 EEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELTQIAWKHDVQVMIEGPG 439 EEICEIMK YD++FSLGDGLRPGSI DANDEAQ EL TLGELTQIAWKHDVQVMIEGPG Sbjct: 335 EEICEIMKMYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTQIAWKHDVQVMIEGPG 394 Query: 440 HVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYV 499 HVPMH IKEN+D Q++ C EAPFYTLGPLTTDIAPGYDHITS IGAA IGWYGTAMLCYV Sbjct: 395 HVPMHKIKENVDKQMDICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYV 454 Query: 500 TPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNIG 559 TPKEHLGLPN+ DV++G+ITYKIAAHAADLAKGHPGAQIRD+ALSKARFEFRW DQFN+ Sbjct: 455 TPKEHLGLPNRDDVREGVITYKIAAHAADLAKGHPGAQIRDDALSKARFEFRWRDQFNLS 514 Query: 560 LDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDYAAKEGISEIDALKQGM 619 LDP++A E+HDETLP + AK AHFCSMCGP FCSM+I+Q++RDYA K +SE +A+ +G+ Sbjct: 515 LDPERALEYHDETLPAEGAKTAHFCSMCGPKFCSMRISQDIRDYAKKNDLSEAEAINKGL 574 Query: 620 QVKSVEFVKMGAEIY 634 + K+ EFV G+ +Y Sbjct: 575 KEKAKEFVDTGSNLY 589