BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0037.p (301 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1280 [G] COG0524 Sugar kinases, ribokinase family Rso Ralston... 314 1e-85 DR0728 [G] COG0524 Sugar kinases, ribokinase family Dra Deinococ... 239 4e-63 alr0517 [G] COG0524 Sugar kinases, ribokinase family Nos Nostoc ... 103 4e-22 TM0296 [G] COG0524 Sugar kinases, ribokinase family Tma Thermoto... 102 8e-22 ECs3242 [G] COG0524 Sugar kinases, ribokinase family Ecs Escheri... 100 3e-21 SMc02164 [G] COG0524 Sugar kinases, ribokinase family Sme Sinorh... 100 3e-21 BH1857 [G] COG0524 Sugar kinases, ribokinase family Bha Bacillus... 97 4e-20 AGc706 [G] COG0524 Sugar kinases, ribokinase family Atu Agrobact... 96 1e-19 BMEI1833 [G] COG0524 Sugar kinases, ribokinase family Bme Brucel... 93 7e-19 BS_ydjE [G] COG0524 Sugar kinases, ribokinase family Bsu Bacillu... 92 1e-18 >RSp1280 [G] COG0524 Sugar kinases, ribokinase family Rso Ralstonia solanacearum Length = 307 Score = 314 bits (805), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 163/295 (55%), Positives = 208/295 (70%), Gaps = 2/295 (0%) Query: 7 FVVFGEALTDFIRQPDEQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGAELYALT 66 VVFGEALTDFIR+ D +WR++ GG+CWNVAR ARLG PTG+AG+VS DVFG EL AL+ Sbjct: 10 LVVFGEALTDFIREADGRWRSVAGGSCWNVARVCARLGAPTGFAGTVSRDVFGDELTALS 69 Query: 67 QAAGLDMRFTQQYAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWLDDAQVLHF 126 + AGLDMRF +Q A+ PLLAMV + PP YFFIG++SADL FD LP GW++ AQ++HF Sbjct: 70 RQAGLDMRFMRQVARPPLLAMVPAAHPPQYFFIGENSADLAFDTGVLPDGWIEAAQIVHF 129 Query: 127 GCISLTREPLASRLLQIAQEAARRNKKIAFDPNWRKLMDSPSYRLLFQQLLSLSHYVKVS 186 G +SL R+PLA+ LL+ A K+IAFDPN+R M P YR +++ L+ Y+KVS Sbjct: 130 GSLSLARQPLAAHLLETATAVHAAGKRIAFDPNYRDAMAGPDYRPTLRRMAGLASYIKVS 189 Query: 187 DEDLERLFP--GDTNALATLQSLAPQAEILYTLGAKGMQWIKGEQVIDQPAYRVEVIDTV 244 DEDL LFP +T+ALA L++ AP A IL T GA GM I E + QPA V DTV Sbjct: 190 DEDLRGLFPELDETSALAQLRAWAPTAAILMTRGAAGMTLITPEGTLFQPALPTLVADTV 249 Query: 245 GCGDASMGGWIASQLRQPDAPAQVHLQCAAAGAAIAASKAGAYAATWDEVQALIA 299 G GDASMGGW+AS L +P+A HL+ +AA AA ++ GAYA T +E+ + +A Sbjct: 250 GAGDASMGGWLASLLTRPEAMPASHLEFSAASAAAVCARQGAYAPTREEIVSALA 304 >DR0728 [G] COG0524 Sugar kinases, ribokinase family Dra Deinococcus radiodurans Length = 303 Score = 239 bits (611), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 136/299 (45%), Positives = 171/299 (57%), Gaps = 2/299 (0%) Query: 1 MTQSAAFVVFGEALTDFIRQPDEQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGA 60 MT V GEALTD + W A PGGA WNVARA ARLGVP+ +AG+V D FG Sbjct: 1 MTSLPLIVSAGEALTDLVTAGGNTWHAHPGGAGWNVARACARLGVPSAFAGAVGQDNFGD 60 Query: 61 ELYALTQAAGLDMRFTQQYAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWLDD 120 +L+ + AGLD RF Q+ L+A+V ST PP Y F+G++SADLHFDP RLP GWL Sbjct: 61 DLHRESLEAGLDPRFLQRVPAPTLMAVVYSTRPPQYRFLGENSADLHFDPTRLPGGWLGA 120 Query: 121 AQVLHFGCISLTREPLASRLLQIAQEAARRNKKIAFDPNWRKLMDSPSYRLLFQQLLSLS 180 A+ LH G ISL R PLA LL + + A +I+FDPN R P Y +F + + Sbjct: 121 ARWLHVGGISLARWPLADTLLGVIEAARAAGVRISFDPNARIAHRHPDYPAVFAAVTKRA 180 Query: 181 HYVKVSDEDLERLFPG--DTNALATLQSLAPQAEILYTLGAKGMQWIKGEQVIDQPAYRV 238 +K SDEDL FPG + AL L+ L P+ I+ T GA G +D P V Sbjct: 181 DLLKFSDEDLAFFFPGASEAQALQELRGLNPRCPIVVTRGAAGASLYHSAGRVDLPTVPV 240 Query: 239 EVIDTVGCGDASMGGWIASQLRQPDAPAQVHLQCAAAGAAIAASKAGAYAATWDEVQAL 297 EV DTVG GD+ G + S +PDA HL+ A++ + AGAYA T +EV AL Sbjct: 241 EVADTVGAGDSLCAGLLVSATERPDALWTEHLRFGLGAASVTCAHAGAYAPTREEVAAL 299 >alr0517 [G] COG0524 Sugar kinases, ribokinase family Nos Nostoc sp. PCC 7120 Length = 325 Score = 103 bits (258), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 93/298 (31%), Positives = 138/298 (46%), Gaps = 26/298 (8%) Query: 23 EQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGAELYALTQAAGLDMRFTQQYAKA 82 + W A PGGA NVA A +LG P G+ G+V D G L L Q G+D Q+++ A Sbjct: 29 KSWTAYPGGAPANVACALVKLGTPAGFIGAVGEDEPGNVLVKLLQEVGVDTTGVQRHSTA 88 Query: 83 PLLAM-VTSTTPPDYFFIG------DDSADLHFDPQRLPAGWLDDAQVLHFGCISLT--- 132 P + V D F G + AD H ++LP +A L G + L Sbjct: 89 PTRQVYVVRDLAGDRTFAGFGQYDTSEFADTHLQAKQLPESVFQEADFLILGTLELAYPD 148 Query: 133 REPLASRLLQIAQEAARRNKKIAFDPNWRKLM--DSPSYRLLFQQLLSLSHYVKVSDEDL 190 E R L++A++ + KI D NWR + D R Q++ ++K++ E+ Sbjct: 149 SEKAIHRALELAEQ---YDLKIVLDVNWRPVFWHDENIARQKIQEIFKRVDFLKLAKEEA 205 Query: 191 ERLFPGDTNALATLQSLAPQAEILYTLGAKGMQWIKGEQVIDQPAYRVEVIDTVGCGDAS 250 E LF ++ A L +L T G G + GE PA+ V V+DT G GD+ Sbjct: 206 EWLFD-TSDPGAITYRLGSIEGVLVTDGENGCGYCLGENEGKIPAFAVSVVDTTGAGDSF 264 Query: 251 MGGWIASQLRQ------PDAP-AQVHLQCAAAGAAIAASKAGAYAA--TWDEVQALIA 299 + G+I QL + DA A+ + A+A A+ +KAGA A+ T EV+ +A Sbjct: 265 LAGFI-HQLSEHGIHNLNDAETAKRIITYASAVGALTTTKAGAIASQPTAMEVETFLA 321 >TM0296 [G] COG0524 Sugar kinases, ribokinase family Tma Thermotoga maritima Length = 315 Score = 102 bits (255), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 84/310 (27%), Positives = 137/310 (44%), Gaps = 24/310 (7%) Query: 11 GEALTDFIRQPD-------EQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGAELY 63 GE L DFI + E +R GG+ NVA A RLG + G + D F L Sbjct: 7 GEILIDFISEDKGKNLSQSELFRKKAGGSPLNVAVALKRLGREVSFLGKLGGDQFSEFLL 66 Query: 64 ALTQAAGLD---MRFTQQYAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWLDD 120 + + G+D + F + PD+ F + AD + P+ + +D Sbjct: 67 EVMKKEGIDTTHIIFDSSCKTTLAFVARDAQGNPDFVFFREKPADTNLRPEEV---NIDP 123 Query: 121 AQV--LHFGCISLTREPLASRLLQIAQEAARRNKKIAFDPNWRK--LMDSPSYRLLFQQL 176 AQ LH G SL EP S L++ + K +++DPN R + D ++ F ++ Sbjct: 124 AQFSFLHIGSYSLAVEPSRSAYLKVMETFLEEGKPVSYDPNVRPSLIEDRNTFVKDFLEI 183 Query: 177 LSLSHYVKVSDEDLERLFPGDTNALATLQSLAPQAEILYTLGAKG-MQWIKGEQVIDQPA 235 S VK+SD+DLE +F D + + T+G +G + KGE+ + P+ Sbjct: 184 SSKVDIVKLSDKDLEYIFQEDLETAVDKIPIKENGLLFVTMGERGCLVKFKGEKRM-VPS 242 Query: 236 YRVEVIDTVGCGDASMGGWIASQLRQPDAPAQVHLQC---AAAGAAIAASKAGAYAA--T 290 ++V+ +D GCGD+ I L + + ++ A A AAI ++ G A Sbjct: 243 FKVKPVDATGCGDSFTAAVIHKYLEKTPETIEDAVEIGKFANAVAAIVITRVGGVDAMPV 302 Query: 291 WDEVQALIAH 300 DEV+ +++ Sbjct: 303 LDEVEMFLSN 312 >ECs3242 [G] COG0524 Sugar kinases, ribokinase family Ecs Escherichia coli O157:H7 Length = 304 Score = 100 bits (250), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 88/298 (29%), Positives = 137/298 (45%), Gaps = 15/298 (5%) Query: 4 SAAFVVFGEALTDFIRQPDEQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGAELY 63 SA V G+A+ D + + D + PGGA NVA ARLG +G+ G V D FGA + Sbjct: 2 SAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALMQ 61 Query: 64 ALTQAAGLDMRFTQQ---YAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWLDD 120 G+D+ + +Q + + +L + + F+ SADL + LP W Sbjct: 62 RTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPC-W-RH 119 Query: 121 AQVLHFGCISLTREPLASRLLQIAQEAARRNKKIAFDPNWRKLM--DSPSYRLLFQQLLS 178 + LH I+L+ EP + E ++FDPN R+ + D RL +Q L Sbjct: 120 GEWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIREDLWQDEHLLRLCLRQALQ 179 Query: 179 LSHYVKVSDEDLERLFPGDTNALATLQSLAPQAEI---LYTLGAKGMQWIKGEQVIDQPA 235 L+ VK+S+E+ RL G T + +LA + EI L T GA+G+ QV Sbjct: 180 LADVVKLSEEEW-RLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAG 238 Query: 236 YRVEVIDTVGCGDASMGGWI----ASQLRQPDAPAQVHLQCAAAGAAIAASKAGAYAA 289 V+ +D+ G GDA + G + ++ L + + + A A+A + GA A Sbjct: 239 MSVDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTA 296 >SMc02164 [G] COG0524 Sugar kinases, ribokinase family Sme Sinorhizobium meliloti Length = 308 Score = 100 bits (250), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 88/259 (33%), Positives = 121/259 (46%), Gaps = 12/259 (4%) Query: 8 VVFGEALTDFIRQP----DEQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGAELY 63 V GEAL D + + + + GGA +N A A RLGVPTG+ +S D+FG L Sbjct: 3 VCCGEALIDMLPRETTAGESAFAPYAGGAIFNTAVALGRLGVPTGFFTGLSDDMFGDILR 62 Query: 64 ALTQAAGLDMRFTQQYAKAPLLAMVTSTT-PPDYFFIGDDSADLHFDPQRLPAGWLDDAQ 122 A +AA +D LA V Y F +++A + LPA D + Sbjct: 63 ATLKAANVDFAPCATLPLHTTLAFVKLVDGHASYAFFDENTAGRMITAEHLPA-LGDFCE 121 Query: 123 VLHFGCISLTREPLASRLLQI-AQEAARRNKKIAFDPNWRK--LMDSPSYRLLFQQLLSL 179 LHFG ISL EP S + A+E +R I+FDPN R + D ++ ++ ++ Sbjct: 122 ALHFGAISLIPEPCGSTYEALMAREHEKR--VISFDPNIRPGFIKDREAHVGRMNRMAAM 179 Query: 180 SHYVKVSDEDLERL-FPGDTNALATLQSLAPQAEILYTLGAKGMQWIKGEQVIDQPAYRV 238 S VK SDEDL G +ALA +L T GA G ++ + RV Sbjct: 180 SDIVKFSDEDLAWFGMEGSHDALAAEWLKRGPKLVLITRGADGAVGYTNGHKVEVASERV 239 Query: 239 EVIDTVGCGDASMGGWIAS 257 EV+DTVG GD G +AS Sbjct: 240 EVVDTVGAGDTFDAGVLAS 258 >BH1857 [G] COG0524 Sugar kinases, ribokinase family Bha Bacillus halodurans Length = 319 Score = 97.1 bits (240), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 83/301 (27%), Positives = 132/301 (43%), Gaps = 14/301 (4%) Query: 8 VVFGEALTDFI--RQPDEQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGAELYAL 65 + GEAL DFI +E ++ PGGA NVA A+LG + + G V D+ G L Sbjct: 6 ICLGEALIDFIPMDSTNEIYQKSPGGAPANVAVGLAKLGAKSTFVGKVGDDLLGRFLKET 65 Query: 66 TQAAGLD---MRFTQQYAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWLDDAQ 122 A ++ M F+++ + + + F + SAD + + ++ Sbjct: 66 LTKANVNTEHMLFSKEVRTGATFVTLAANGERSFDFYINPSADRFLEKGEIAPTLFEEHG 125 Query: 123 VLHFGCISLTREPLASRLLQIAQEAARRNKKIAFDPNWRKLM--DSPSYRLLFQQLLSLS 180 VLHFG ISL EP + A + I++DPN R + D RLL +L + Sbjct: 126 VLHFGSISLISEPARTATRHAVSLAKKNGLMISYDPNLRLNLWEDEEQARLLITSMLGEA 185 Query: 181 HYVKVSDEDLERLFPGDTNALATLQSLAPQA--EILYTLGAKG--MQWIKGEQVIDQPAY 236 +K+S+E+L G+ A L L + TLG KG + + ++ I PA Sbjct: 186 DVLKISEEEL-AFITGEQTIEAGLDQLVAYNIPLVFVTLGEKGSIVSYNGIQRKI--PAM 242 Query: 237 RVEVIDTVGCGDASMGGWIASQLRQPDAPAQVHLQCAAAGAAIAASKAGAYAATWDEVQA 296 V+ +DT G GDA + + + A++ ++ A A+ G AAT + A Sbjct: 243 AVQTVDTTGAGDAFVSAILFKLQEERKQVAELSIKEVEQMARFASVSGGLAAATKGAMTA 302 Query: 297 L 297 L Sbjct: 303 L 303 >AGc706 [G] COG0524 Sugar kinases, ribokinase family Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 313 Score = 95.9 bits (237), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 80/265 (30%), Positives = 121/265 (45%), Gaps = 10/265 (3%) Query: 1 MTQSAAFVVFGEALTDFI-RQP---DEQWRAIPGGACWNVARAAARLGVPTGYAGSVSTD 56 M ++ + GEAL D + RQ + + GGA +N A A RLGVP+ + +S D Sbjct: 1 MRRTVMILCCGEALIDMLPRQTTLGEAGFAPYAGGAVFNTAIALGRLGVPSAFFTGLSDD 60 Query: 57 VFGAELYALTQAAGLDMRFTQQYAKAPLLAMVTSTT-PPDYFFIGDDSADLHFDPQRLPA 115 + G L +A+ +D + ++ +A V Y F +++A LPA Sbjct: 61 MMGDILRETLRASKVDFSYCATLSRPTTIAFVKLVDGHATYAFYDENTAGRMITEAELPA 120 Query: 116 GWLDDAQVLHFGCISLTREPLASRLLQIAQEAARRNKKIAFDPNWRK--LMDSPSYRLLF 173 D + LHFG ISL EP S + + I+ DPN R + + S+ Sbjct: 121 -LGADCEALHFGAISLIPEPCGST-YEALMTREHETRVISLDPNIRPGFIQNKQSHMARI 178 Query: 174 QQLLSLSHYVKVSDEDLERL-FPGDTNALATLQSLAPQAEILYTLGAKGMQWIKGEQVID 232 +++ ++S VK SDEDL GD + LA ++ T GAKG ++ Sbjct: 179 RRMAAMSDIVKFSDEDLAWFGLEGDEDTLARHWLHHGAKLVVVTRGAKGAVGYSANLKVE 238 Query: 233 QPAYRVEVIDTVGCGDASMGGWIAS 257 + RVEV+DTVG GD G +AS Sbjct: 239 VASERVEVVDTVGAGDTFDAGILAS 263 >BMEI1833 [G] COG0524 Sugar kinases, ribokinase family Bme Brucella melitensis Length = 308 Score = 93.2 bits (230), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 89/298 (29%), Positives = 139/298 (46%), Gaps = 27/298 (9%) Query: 11 GEALTDFIRQP----DEQWRAIPGGACWNVARAAARLGVPTGYAGSVSTDVFGAELYALT 66 GEAL D + + + ++ GG+ +N A A RLGVPTG+ +S+D FG L Sbjct: 6 GEALIDMLPRETTGGETAFQPFAGGSVFNTAIALGRLGVPTGFFSGISSDFFGDVLRDTL 65 Query: 67 QAAGLDMRFTQQYAKAPLLAMVTSTT-PPDYFFIGDDSADLHFDPQRLPAGWLDDA-QVL 124 + +D F + LA V Y F +++A +P ++D+ + Sbjct: 66 ARSNVDYSFAAISNRPTTLAFVRLVDGQARYAFYDENTAGRMLSRNDMP--YVDETISAM 123 Query: 125 HFGCISLTREPLASRL-LQIAQEAARRNKKIAFDPNWRKLMDS--PSYRLLFQQLLSLSH 181 FGCISL EP S +A+EA N+ + DPN R + + ++ +++++L+ Sbjct: 124 LFGCISLISEPCGSVYETLLAREAP--NRVMFLDPNIRANLITVRETHLTRVKRMIALAD 181 Query: 182 YVKVSDEDLERLF-PGDTNALATL-QSLAPQAEILYTLGAKGMQWIKGEQVIDQPAYRVE 239 VK+SDEDL+ G + +A L P+ ++ T GA G + P +V+ Sbjct: 182 IVKLSDEDLDWFGEKGSHDEIAAEWLKLGPKL-VVITKGAHGAVAYTNHATVPVPGVKVD 240 Query: 240 VIDTVGCGDASMGGWIAS----QLRQPDAPA-----QVHLQCAAA--GAAIAASKAGA 286 V+DTVG GD G +AS L DA A Q+H A A + S+AGA Sbjct: 241 VVDTVGAGDTVNAGILASLHSQGLLTKDALANLSEDQIHSAVALGVRAATVTVSRAGA 298 >BS_ydjE [G] COG0524 Sugar kinases, ribokinase family Bsu Bacillus subtilis Length = 320 Score = 92.4 bits (228), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 87/303 (28%), Positives = 134/303 (44%), Gaps = 17/303 (5%) Query: 3 QSAAFVVFGEALTDFI-------RQPDEQWRAIPGGACWNVARAAARLGVPTGYAGSVST 55 +S + V GE L DF Q+ GGA NV+ A A+LG ++G V Sbjct: 2 RSHSVVCIGELLIDFFCTDVDVDLMEGRQFLKSAGGAPANVSAAIAKLGGDAAFSGKVGK 61 Query: 56 DVFGAELYALTQAAGLDMRFTQQYAKAP-LLAMVTSTTPPDYFFIGDDSADLHFDPQRLP 114 D FG L A +D KAP LA V+ + F+ + AD F + + Sbjct: 62 DPFGYFLKRTLDAVHVDTSMLVMDEKAPTTLAFVSLKQNGERDFVFNRGADALFTLEDID 121 Query: 115 AGWLDDAQVLHFGC-ISLTREPLASRLLQIAQEAARRNKKIAFDPNWRKLM---DSPSYR 170 L++A++LHFG +L +P S L++ A + I+FDPN+R+ + + Sbjct: 122 QEKLNEAKILHFGSATALLSDPFCSAYLRLMSIAKDNGQFISFDPNYREDLWRGRVSEFV 181 Query: 171 LLFQQLLSLSHYVKVSDEDLERL--FPGDTNALATLQSLAPQAEILYTLGAKGMQWIKGE 228 + ++ +++S +VKVSDE+LE + +A L + + TLG G G+ Sbjct: 182 SVAKKAIAVSDFVKVSDEELEIISGVKDHEKGVAILHEIGANI-VAVTLGKSGTLLSNGK 240 Query: 229 QVIDQPAYRVEVIDTVGCGDASMGGWIASQLRQPDAPAQVHLQCAAAGAAIA-ASKAGAY 287 P+ V ID+ G GDA +G + QL D V +A A+K GA Sbjct: 241 DREIIPSIPVTSIDSTGAGDAFVGAAL-YQLANTDQIQSVDADFVKLREIVAFANKVGAL 299 Query: 288 AAT 290 T Sbjct: 300 VCT 302