BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0021.p (916 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2230_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and p... 935 0.0 VC0108_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and po... 748 0.0 NMA0462_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and p... 729 0.0 NMB1982_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and p... 725 0.0 PA5493_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and po... 724 0.0 HI0856_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and po... 717 0.0 polA_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and poly... 713 0.0 ZpolA_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and pol... 713 0.0 ECs4786_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and p... 712 0.0 YPO0017_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and p... 710 0.0 >RSc2230_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains Rso Ralstonia solanacearum Length = 651 Score = 935 bits (2417), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/624 (71%), Positives = 532/624 (85%), Gaps = 16/624 (2%) Query: 309 GLF---AAAPKVEYETVLTDAQLDQWIATINAAELTAVDTETTSLEAMQAELVGISLCCE 365 GLF A +V+YETV T+AQL+ W+ ++A+EL +DTETTS++ M A+LVG+SL E Sbjct: 28 GLFDVEAPPAEVKYETVTTEAQLESWMRLLDASELVCIDTETTSIDPMLAQLVGLSLSVE 87 Query: 366 PGRAAYIPVAH-----NYQDAPVQLSRQHVLEKLKPWLEDASKPKLGQHLKYDSHIFANY 420 PG+A YIPVAH + DA QLSR+ VL ++KPWLEDA++ K+GQHLKYD+H+FAN+ Sbjct: 88 PGQACYIPVAHRGPDVSGLDAAGQLSREAVLARMKPWLEDAARKKVGQHLKYDAHVFANH 147 Query: 421 GVRLAGVQHDTLLESYVFESHRPHDMDSLAARHLERKTITYAEVCGKGASQIGFNEVAIE 480 G+ L G+ HDT+L+SYV SHR H MD+LA R L KTITY EVCGKGASQIGF+EV ++ Sbjct: 148 GIALRGIAHDTMLQSYVLASHRNHGMDALAERVLHLKTITYEEVCGKGASQIGFDEVPLD 207 Query: 481 RATEYAAEDAEVTLALHQAMWPQIEHDDKLRFIYEKIEVPTSVVLQKIERNGVLIDSERL 540 RATEYAAEDA++TL LH+A++P++ DDKLR++YE+IE+PTS+VLQK+ERNGVLID+ERL Sbjct: 208 RATEYAAEDADITLRLHRALYPKVAEDDKLRYVYEQIEMPTSIVLQKMERNGVLIDAERL 267 Query: 541 GQQSHDLGKRMLEIEQQAYDLAGQPFNLNSPKQLGEILFGKLELPVVKKTASGAPSTDEE 600 +QS LG+R+LE+EQQAY LAGQPFNLNSPKQ+GEI F +L+LPV+KKTASGAPSTDEE Sbjct: 268 ARQSTGLGQRLLELEQQAYALAGQPFNLNSPKQIGEIFFTQLKLPVIKKTASGAPSTDEE 327 Query: 601 VLQKLAEDYPLPKVLLDYRGLAKLKSTYTDKLPKMVNPATGRVHTNYAQAVAVTGRLSSN 660 VLQKLAEDYPLPK+LLD+RGLAKLKSTYTDKLPKMVNP TGRVHT Y QA AVTGRL+S Sbjct: 328 VLQKLAEDYPLPKLLLDFRGLAKLKSTYTDKLPKMVNPQTGRVHTTYGQATAVTGRLAST 387 Query: 661 DPNLQNIPIRTAEGRRIREAFVAPEGSVIVSADYSQIELRIMAHISEDENMLKAFANNED 720 DPNLQNIP+RT EGRRIREAFVAP GSVIVSADYSQIELRIMAH+SEDE +L+AF +D Sbjct: 388 DPNLQNIPVRTEEGRRIREAFVAPAGSVIVSADYSQIELRIMAHLSEDEGLLRAFREGQD 447 Query: 721 IHRATAAEIFGIAPEQVESEQRRYAKVINFGLIYGMSAFGLASNLGIERAAAQMYIDKYF 780 +HRATAAE+FG+ P +V +EQRRYAKVINFGLIYGMSAFGLASNLGI R AA++YID+YF Sbjct: 448 VHRATAAEVFGVTPLEVTAEQRRYAKVINFGLIYGMSAFGLASNLGIGRDAAKLYIDRYF 507 Query: 781 MRFSGVKRYMDETRLQAKARGYVETVFGRRLWLPEINSPNGPRRQGAERAAINAPMQGTA 840 R+ GV RYMDETRL A RGYVETVFGRRLWLP+IN NGPRRQ AERAAINAPMQGTA Sbjct: 508 ARYPGVARYMDETRLVAHERGYVETVFGRRLWLPDINGGNGPRRQAAERAAINAPMQGTA 567 Query: 841 ADLIKMAMIAVQDWLETN--------SLQTRMIMQVHDELVLEVPQQELEVVREKLPELM 892 ADLIK++M+AVQDWL+ + ++TR +MQVHDELVLEVPQ+EL +VRE+LPELM Sbjct: 568 ADLIKLSMLAVQDWLDGSPSAGKPGAPMRTRQVMQVHDELVLEVPQEELSLVRERLPELM 627 Query: 893 KNVAELKVPLLAEVGIGKNWDEAH 916 VA L+VPL+AEVG+G NW+EAH Sbjct: 628 CGVASLRVPLVAEVGVGANWEEAH 651 >VC0108_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains Vch Vibrio cholerae Length = 651 Score = 748 bits (1931), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/651 (57%), Positives = 473/651 (72%), Gaps = 7/651 (1%) Query: 273 FRTWLRELSDGAEA-----GASKAPMVGASAAAALEAPAQGGLFAAAPKVEYETVLTDAQ 327 F++WL EL DG +K V S AA A A + +Y+T+L + Sbjct: 1 FKSWLTELLDGGTGIVTADEQTKTSSVTVSTAATHAAAIPESPAAHIDRSQYQTILNEQD 60 Query: 328 LDQWIATINAAELTAVDTETTSLEAMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSR 387 W+ + AEL A DTET +L+ M A LVG+S G AAY+PVAH+Y DAP QL R Sbjct: 61 FQLWLEKLKQAELFAFDTETDNLDYMVANLVGMSFAVAEGEAAYLPVAHDYLDAPQQLER 120 Query: 388 QHVLEKLKPWLEDASKPKLGQHLKYDSHIFANYGVRLAGVQHDTLLESYVFES-HRPHDM 446 V+ +LKP LED SK K+GQ+LKYD+ + A YGV L G++HDT+L+SYV+ S HDM Sbjct: 121 DWVIAQLKPLLEDESKAKVGQNLKYDASVMARYGVELRGIRHDTMLQSYVYNSVGGKHDM 180 Query: 447 DSLAARHLERKTITYAEVCGKGASQIGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEH 506 DSLA R L+ I++ +V GKG +Q+ FN++A+E A +YAAEDA+VTL LHQ + P IE Sbjct: 181 DSLALRFLQHSCISFEQVAGKGKNQLTFNQIALEEAAQYAAEDADVTLRLHQRIHPLIEQ 240 Query: 507 DDKLRFIYEKIEVPTSVVLQKIERNGVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPF 566 D KL +Y +IE+P VL +IER GV+ID L QS ++ R+ ++EQ AY+LAGQPF Sbjct: 241 DAKLEQVYREIEMPLVPVLSRIERTGVMIDDMLLSAQSQEIALRLDQLEQNAYELAGQPF 300 Query: 567 NLNSPKQLGEILFGKLELPVVKKTASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKS 626 NL+SPKQL ILF +++LPV++KT SG PST+EEVLQ+LA DYPLPKVL++YRGLAKLKS Sbjct: 301 NLSSPKQLQTILFEQMKLPVLQKTPSGTPSTNEEVLQELALDYPLPKVLIEYRGLAKLKS 360 Query: 627 TYTDKLPKMVNPATGRVHTNYAQAVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEG 686 TYTDKLPKM+NP+TGRVHT+Y QAV TGRLSS DPNLQNIP+R EGRRIR+AFVAP G Sbjct: 361 TYTDKLPKMINPSTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFVAPHG 420 Query: 687 SVIVSADYSQIELRIMAHISEDENMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAK 746 I++ DYSQIELRIMAH+S D+ +L AF + +DIH ATAAEI G+ +QV SEQRR AK Sbjct: 421 WKIMAVDYSQIELRIMAHLSGDQALLDAFRDGKDIHAATAAEIIGVPIDQVSSEQRRRAK 480 Query: 747 VINFGLIYGMSAFGLASNLGIERAAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETV 806 +NFGLIYGMSAFGLA LGI R AQ Y+DKYF R+ GV +YM++TR +A GYVET+ Sbjct: 481 AVNFGLIYGMSAFGLAKQLGIPRGEAQEYMDKYFERYPGVMQYMEDTRSRAAQLGYVETI 540 Query: 807 FGRRLWLPEINSPNGPRRQGAERAAINAPMQGTAADLIKMAMIAVQDWLE-TNSLQTRMI 865 FGRRL LPEI S N RR+ AERAAINAPMQGTAAD+IK AM+ V +W+E + +++ Sbjct: 541 FGRRLHLPEITSRNAMRRKAAERAAINAPMQGTAADIIKKAMLLVDEWIEREGDGRVKLL 600 Query: 866 MQVHDELVLEVPQQELEVVREKLPELMKNVAELKVPLLAEVGIGKNWDEAH 916 MQVHDELV EV + L + K+ +LM++ AEL VPL+AE G G NW++AH Sbjct: 601 MQVHDELVFEVKESSLSEIESKVQQLMESAAELAVPLVAEAGHGDNWEQAH 651 >NMA0462_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains NmA Neisseria meningitidis Z2491 Length = 638 Score = 729 bits (1881), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/636 (58%), Positives = 466/636 (73%), Gaps = 15/636 (2%) Query: 294 VGASAAAALEAP--AQGGLFAAAPKVEYETVLTDAQLDQWIATINAAELTAVDTETTSLE 351 +G AA E P Q A K++Y+ V T+AQ + ++ A+ +DTETTSL+ Sbjct: 5 IGEQAALNAEMPFEKQAEKATAPEKLDYQAVTTEAQFAALLDKLSRADTIGIDTETTSLD 64 Query: 352 AMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSRQHVLEKLKPWLEDASKPKLGQHLK 411 AM A LVGIS+ + G A YIPV H+ AP QL Q VL +LKP LE+ + K+GQ+LK Sbjct: 65 AMNASLVGISIAFQAGEAVYIPVGHSLTAAPEQLDLQDVLGRLKPHLENPALKKIGQNLK 124 Query: 412 YDSHIFANYGVRLAGVQHDTLLESYVFESHRPHDMDSLAARHLERKTITYAEVCGKGASQ 471 YD H+FANYG+ L G+ D +L SY+ ESH H +D L+ R L +TITY +CGKGA Q Sbjct: 125 YDQHVFANYGIALNGIAGDAMLASYIIESHLGHGLDELSERWLGLETITYESLCGKGAKQ 184 Query: 472 IGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEHDDKLRFIYEKIEVPTSVVLQKIERN 531 I F +VAI +ATEYAA+DA+ L L + Q+ D K +YEK+E+P + VL ++ERN Sbjct: 185 ISFADVAIGQATEYAAQDADFALRLEAHLRAQM--DAKQLEMYEKMELPVAQVLFEMERN 242 Query: 532 GVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPFNLNSPKQLGEILFGKLELPV--VKK 589 GV ID L +QS +LG ++++EQ+AY AGQPFNLNSPKQL EILF K+ +P +KK Sbjct: 243 GVQIDRAELARQSAELGAELMKLEQEAYAAAGQPFNLNSPKQLQEILFDKMGIPTKGLKK 302 Query: 590 TASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKSTYTDKLPKMVNPATGRVHTNYAQ 649 TA G ST+E VL++LA DYPLPK++L R LAKLKSTYTDKLP+M++P GRVHT YAQ Sbjct: 303 TAKGGISTNEAVLEQLAPDYPLPKIILQNRSLAKLKSTYTDKLPEMISPKDGRVHTTYAQ 362 Query: 650 AVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEGSVIVSADYSQIELRIMAHISEDE 709 AVA+TGRL+SN+PNLQNIPIRTAEGRR+R AF AP+GSVIVSADYSQIELRIMAH+S D+ Sbjct: 363 AVAITGRLASNNPNLQNIPIRTAEGRRVRRAFTAPQGSVIVSADYSQIELRIMAHLSGDK 422 Query: 710 NMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAKVINFGLIYGMSAFGLASNLGIER 769 ++ AF N ED+HR TAAE+FGIAPE V SEQRRYAK INFGLIYGM +GLA +LGI+ Sbjct: 423 TLIAAFQNGEDVHRRTAAEVFGIAPENVSSEQRRYAKTINFGLIYGMGQYGLAKSLGIDN 482 Query: 770 AAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETVFGRRLWLPEINSPNGPRRQGAER 829 +A+ +ID+YF R+ GV YM T+ QA A+G+VET+FGRRL+LP+I + N R GAER Sbjct: 483 ISAKNFIDRYFARYPGVAEYMQRTKEQAAAQGFVETLFGRRLYLPDIRNKNTNARAGAER 542 Query: 830 AAINAPMQGTAADLIKMAMIAVQDWLETNS-------LQTRMIMQVHDELVLEVPQQELE 882 AAINAPMQGTA+DLIK AMI V WL LQ+++IMQVHDELVLEV + EL+ Sbjct: 543 AAINAPMQGTASDLIKRAMIDVSRWLSECEASPWDELLQSKLIMQVHDELVLEVVETELD 602 Query: 883 VVREKLPELMKNV--AELKVPLLAEVGIGKNWDEAH 916 V+EKLP++M V L VPL+AEVG+G+NW+EAH Sbjct: 603 FVKEKLPQIMAKVDGGLLDVPLVAEVGVGENWEEAH 638 >NMB1982_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains Nme Neisseria meningitidis MC58 Length = 638 Score = 725 bits (1872), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/636 (57%), Positives = 465/636 (73%), Gaps = 15/636 (2%) Query: 294 VGASAAAALEAP--AQGGLFAAAPKVEYETVLTDAQLDQWIATINAAELTAVDTETTSLE 351 +G AA E P Q A K++Y+ V T+AQ + ++ A+ +DTETTSL+ Sbjct: 5 IGEQAALNAEMPFEKQAEKATAPEKLDYQAVTTEAQFAALLDKLSRADTIGIDTETTSLD 64 Query: 352 AMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSRQHVLEKLKPWLEDASKPKLGQHLK 411 AM A LVGIS+ + G A YIPV H+ AP QL Q VL +LKP L + + K+GQ+LK Sbjct: 65 AMNASLVGISIAFQAGEAVYIPVGHSLTAAPEQLDLQDVLGRLKPHLGNPALKKIGQNLK 124 Query: 412 YDSHIFANYGVRLAGVQHDTLLESYVFESHRPHDMDSLAARHLERKTITYAEVCGKGASQ 471 YD H+FANYG+ L G+ D +L SY+ ESH H +D L+ R L +TITY +CGKGA Q Sbjct: 125 YDQHVFANYGIALNGIAGDAMLASYIIESHLGHGLDELSERWLGLETITYESLCGKGAKQ 184 Query: 472 IGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEHDDKLRFIYEKIEVPTSVVLQKIERN 531 IGF +VAI +ATEYAA+DA+ L L + Q+ D+K +YEK+E+P + VL ++ERN Sbjct: 185 IGFADVAIGQATEYAAQDADFALRLEAHLRAQM--DEKQLEMYEKMELPVAQVLFEMERN 242 Query: 532 GVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPFNLNSPKQLGEILFGKLELPV--VKK 589 GV ID L +QS +LG ++++EQ+AY AGQPFNLNSPKQL EILF K+ +P +KK Sbjct: 243 GVQIDRAELARQSAELGAELMKLEQEAYAAAGQPFNLNSPKQLQEILFDKMGIPTKGLKK 302 Query: 590 TASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKSTYTDKLPKMVNPATGRVHTNYAQ 649 TA G ST+E VL++LA DYPLPK++L R LAKLKSTYTDKLP+M++P GRVHT YAQ Sbjct: 303 TAKGGISTNEAVLEQLAPDYPLPKIILQNRSLAKLKSTYTDKLPEMISPKDGRVHTTYAQ 362 Query: 650 AVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEGSVIVSADYSQIELRIMAHISEDE 709 AVA+TGRL+SN+PNLQNIPIRT EGR++R AF AP+GSVIVSADYSQIELRIMAH+S D+ Sbjct: 363 AVAITGRLASNNPNLQNIPIRTEEGRKVRRAFTAPQGSVIVSADYSQIELRIMAHLSGDK 422 Query: 710 NMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAKVINFGLIYGMSAFGLASNLGIER 769 ++ AF N ED+HR TAAE+FG APE V SEQRRYAK INFGLIYGM +GLA +LGI+ Sbjct: 423 TLIAAFQNGEDVHRRTAAEVFGTAPENVSSEQRRYAKSINFGLIYGMGQYGLAKSLGIDN 482 Query: 770 AAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETVFGRRLWLPEINSPNGPRRQGAER 829 +A+ +ID+YF R+ GV YM T+ QA A+GYVET+FGRRL+LP+I + N R GAER Sbjct: 483 LSAKNFIDRYFARYPGVAEYMQRTKEQAAAQGYVETLFGRRLYLPDIRNKNANARAGAER 542 Query: 830 AAINAPMQGTAADLIKMAMIAVQDWLETNS-------LQTRMIMQVHDELVLEVPQQELE 882 AAINAPMQGTA+DLIK AMI V WL LQ+++IMQVHDELVLEV + EL+ Sbjct: 543 AAINAPMQGTASDLIKRAMIDVSRWLSECEASPWDELLQSKLIMQVHDELVLEVVETELD 602 Query: 883 VVREKLPELMKNV--AELKVPLLAEVGIGKNWDEAH 916 V+EKLP++M V L VPL+AEVG+G+NW+EAH Sbjct: 603 FVKEKLPQIMAKVDGGLLDVPLVAEVGVGENWEEAH 638 >PA5493_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains Pae Pseudomonas aeruginosa Length = 603 Score = 724 bits (1868), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/603 (58%), Positives = 454/603 (75%), Gaps = 4/603 (0%) Query: 318 EYETVLTDAQLDQWIATINAAELTAVDTETTSLEAMQAELVGISLCCEPGRAAYIPVAHN 377 +Y+ VL A D W+ + AEL A DTETTS++A QA++VG+S + G AAY+P+AH+ Sbjct: 1 DYDVVLDQAGFDAWLKKLEEAELIAFDTETTSIDAQQAQVVGVSFAVKEGEAAYVPLAHS 60 Query: 378 YQDAPVQLSRQHVLEKLKPWLEDASKPKLGQHLKYDSHIFANYG--VRLAGVQHDTLLES 435 Y P QL R VL LKP LED K K+GQH KYD ++ AN + L GV +DT+LES Sbjct: 61 YMGVPEQLDRDAVLRALKPLLEDPKKLKVGQHAKYDINVLANASTPIALRGVAYDTMLES 120 Query: 436 YVFESHRP-HDMDSLAARHLERKTITYAEVCGKGASQIGFNEVAIERATEYAAEDAEVTL 494 YV +S HDMDSLA ++L TI + ++ GKGA Q+ F+++AIE+A YAAEDA+VTL Sbjct: 121 YVLDSTATRHDMDSLALKYLGHSTIRFEDIAGKGAKQLTFDQIAIEQAGPYAAEDADVTL 180 Query: 495 ALHQAMWPQIEHDDKLRFIYEKIEVPTSVVLQKIERNGVLIDSERLGQQSHDLGKRMLEI 554 LHQA+W ++E L + IE+P VL +IERNG L+D+ LG QS +LG++M+ + Sbjct: 181 RLHQALWQKLEAIPSLARVLTDIEMPLVPVLARIERNGALVDANLLGIQSRELGEKMVAL 240 Query: 555 EQQAYDLAGQPFNLNSPKQLGEILFGKLELPVVKKTASGAPSTDEEVLQKLAE-DYPLPK 613 E+QAYDLAGQ FNL SPKQLG IL+ KL LPV+ KTA+G PST E VL +LAE D+ LPK Sbjct: 241 ERQAYDLAGQEFNLGSPKQLGAILYDKLGLPVLSKTATGQPSTAEAVLAELAEQDFELPK 300 Query: 614 VLLDYRGLAKLKSTYTDKLPKMVNPATGRVHTNYAQAVAVTGRLSSNDPNLQNIPIRTAE 673 V++ YR ++KLKSTYTD+LP+ +NP TGR+HT+Y QAVA TGRLSS+DPNLQNIPIRTAE Sbjct: 301 VIMQYRSMSKLKSTYTDRLPEQINPRTGRIHTSYHQAVAATGRLSSSDPNLQNIPIRTAE 360 Query: 674 GRRIREAFVAPEGSVIVSADYSQIELRIMAHISEDENMLKAFANNEDIHRATAAEIFGIA 733 GRRIR+AFVAP+G +++ADYSQIELRIMAH+++D+ +L AF ++ D+HRATAAE+FG+ Sbjct: 361 GRRIRQAFVAPQGYKLLAADYSQIELRIMAHLAKDDGLLDAFRHDLDVHRATAAEVFGVP 420 Query: 734 PEQVESEQRRYAKVINFGLIYGMSAFGLASNLGIERAAAQMYIDKYFMRFSGVKRYMDET 793 E V +QRR AK INFGLIYGMSAFGLA +G+ER AQ YID+YF R+ GV YM+ T Sbjct: 421 LEDVSGDQRRSAKAINFGLIYGMSAFGLAKQIGVERKEAQAYIDRYFARYPGVLAYMERT 480 Query: 794 RLQAKARGYVETVFGRRLWLPEINSPNGPRRQGAERAAINAPMQGTAADLIKMAMIAVQD 853 R QA +G+VET+FGRRL+LPEI+S NG R+ AER AINAPMQGTAAD++K AM+AV + Sbjct: 481 RAQAAEQGFVETLFGRRLYLPEIHSKNGAMRKAAERTAINAPMQGTAADIMKRAMVAVDN 540 Query: 854 WLETNSLQTRMIMQVHDELVLEVPQQELEVVREKLPELMKNVAELKVPLLAEVGIGKNWD 913 WL+ + L R+I+QVHDELVLEV + +E V E + LM A L VPL+ E G+G NWD Sbjct: 541 WLQESGLDARVILQVHDELVLEVREDLVEQVCEGIRPLMSGAATLDVPLVVEAGVGSNWD 600 Query: 914 EAH 916 EAH Sbjct: 601 EAH 603 >HI0856_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains Hin Haemophilus influenzae Length = 648 Score = 717 bits (1852), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/648 (54%), Positives = 475/648 (73%), Gaps = 5/648 (0%) Query: 273 FRTWLRELSDGAEA--GASKAP--MVGASAAAALEAPAQGGLFAAAPKVEYETVLTDAQL 328 F+ WL E+ +GA++ ++ P M A + ++ + + +YET+LT A L Sbjct: 2 FKRWLNEVMNGADSITQTTEQPVKMNQYKATSQDQSAVENTPKIQIDRTKYETLLTQADL 61 Query: 329 DQWIATINAAELTAVDTETTSLEAMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSRQ 388 +WI +NAA+L AVDTET SL+ M A LVGIS E G AAY+P+ +Y DAP L + Sbjct: 62 TRWIEKLNAAKLIAVDTETDSLDYMSANLVGISFALENGEAAYLPLQLDYLDAPKTLEKS 121 Query: 389 HVLEKLKPWLEDASKPKLGQHLKYDSHIFANYGVRLAGVQHDTLLESYVFESHRPHDMDS 448 L +KP LE+ + K+GQ++K+D IFA +G+ L GV+ DT+L SY S H+MD Sbjct: 122 TALAAIKPILENPNIHKIGQNIKFDESIFARHGIELQGVEFDTMLLSYTLNSTGRHNMDD 181 Query: 449 LAARHLERKTITYAEVCGKGASQIGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEHDD 508 LA R+L +TI + + GKG SQ+ FN++ +E+ATEYAAEDA+VT+ L QA+W +++ + Sbjct: 182 LAKRYLGHETIAFESLAGKGKSQLTFNQIPLEQATEYAAEDADVTMKLQQALWLKLQEEP 241 Query: 509 KLRFIYEKIEVPTSVVLQKIERNGVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPFNL 568 L +Y+ +E+P VL ++ER GVLIDS+ L QS+++ R+ +E+QAY LAGQPFNL Sbjct: 242 TLVELYKTMELPLLHVLSRMERTGVLIDSDALFMQSNEIASRLTALEKQAYALAGQPFNL 301 Query: 569 NSPKQLGEILFGKLELPVVKKTASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKSTY 628 S KQL EILF KLELPV++KT GAPST+EEVL++L+ + LPK+L+ +RGL+KLKSTY Sbjct: 302 ASTKQLQEILFDKLELPVLQKTPKGAPSTNEEVLEELSYSHELPKILVKHRGLSKLKSTY 361 Query: 629 TDKLPKMVNPATGRVHTNYAQAVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEGSV 688 TDKLP+MVN TGRVHT+Y QAV TGRLSS+DPNLQNIPIR EGR IR+AF+A EG Sbjct: 362 TDKLPQMVNSQTGRVHTSYHQAVTATGRLSSSDPNLQNIPIRNEEGRHIRQAFIAREGYS 421 Query: 689 IVSADYSQIELRIMAHISEDENMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAKVI 748 IV+ADYSQIELRIMAH+S D+ ++ AF+ +DIHR+TAAEIFG++ ++V SEQRR AK I Sbjct: 422 IVAADYSQIELRIMAHLSGDQGLINAFSQGKDIHRSTAAEIFGVSLDEVTSEQRRNAKAI 481 Query: 749 NFGLIYGMSAFGLASNLGIERAAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETVFG 808 NFGLIYGMSAFGL+ LGI RA AQ Y+D YF R+ V+++M + R +AKA+GYVET+FG Sbjct: 482 NFGLIYGMSAFGLSRQLGISRADAQKYMDLYFQRYPSVQQFMTDIREKAKAQGYVETLFG 541 Query: 809 RRLWLPEINSPNGPRRQGAERAAINAPMQGTAADLIKMAMIAVQDWLETNSLQTRMIMQV 868 RRL+LP+INS N RR+GAER AINAPMQGTAAD+IK AMI + + + + MIMQV Sbjct: 542 RRLYLPDINSSNAMRRKGAERVAINAPMQGTAADIIKRAMIKLDEVIRHDP-DIEMIMQV 600 Query: 869 HDELVLEVPQQELEVVREKLPELMKNVAELKVPLLAEVGIGKNWDEAH 916 HDELV EV +++ RE++ + M+ AEL VPL+ EVG+G+NWDEAH Sbjct: 601 HDELVFEVRSEKVAFFREQIKQHMEAAAELVVPLIVEVGVGQNWDEAH 648 >polA_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains Eco Escherichia coli K12 Length = 640 Score = 713 bits (1841), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/631 (59%), Positives = 456/631 (72%), Gaps = 12/631 (1%) Query: 295 GASAAAALEAPAQGGLFAAAPKV--------EYETVLTDAQLDQWIATINAAELTAVDTE 346 GA AA P + + AP+V Y T+L + L WIA + A + A DTE Sbjct: 13 GAKPAAK---PQETSVADEAPEVTATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTE 69 Query: 347 TTSLEAMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSRQHVLEKLKPWLEDASKPKL 406 T SL+ + A LVG+S EPG AAYIPVAH+Y DAP Q+SR+ LE LKP LED K+ Sbjct: 70 TDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKV 129 Query: 407 GQHLKYDSHIFANYGVRLAGVQHDTLLESYVFES-HRPHDMDSLAARHLERKTITYAEVC 465 GQ+LKYD I ANYG+ L G+ DT+LESY+ S HDMDSLA R L+ KTIT+ E+ Sbjct: 130 GQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIA 189 Query: 466 GKGASQIGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEHDDKLRFIYEKIEVPTSVVL 525 GKG +Q+ FN++A+E A YAAEDA+VTL LH MWP ++ ++E IE+P VL Sbjct: 190 GKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVL 249 Query: 526 QKIERNGVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPFNLNSPKQLGEILFGKLELP 585 +IERNGV ID + L S +L R+ E+E++A+++AG+ FNL+S KQL ILF K + Sbjct: 250 SRIERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIK 309 Query: 586 VVKKTASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKSTYTDKLPKMVNPATGRVHT 645 +KKT GAPST EEVL++LA DYPLPKV+L+YRGLAKLKSTYTDKLP M+NP TGRVHT Sbjct: 310 PLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVHT 369 Query: 646 NYAQAVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEGSVIVSADYSQIELRIMAHI 705 +Y QAV TGRLSS DPNLQNIP+R EGRRIR+AF+APE VIVSADYSQIELRIMAH+ Sbjct: 370 SYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHL 429 Query: 706 SEDENMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAKVINFGLIYGMSAFGLASNL 765 S D+ +L AFA +DIHRATAAE+FG+ E V SEQRR AK INFGLIYGMSAFGLA L Sbjct: 430 SRDKGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQL 489 Query: 766 GIERAAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETVFGRRLWLPEINSPNGPRRQ 825 I R AQ Y+D YF R+ GV YM+ TR QAK +GYVET+ GRRL+LP+I S NG RR Sbjct: 490 NIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRA 549 Query: 826 GAERAAINAPMQGTAADLIKMAMIAVQDWLETNSLQTRMIMQVHDELVLEVPQQELEVVR 885 AERAAINAPMQGTAAD+IK AMIAV WL+ + RMIMQVHDELV EV + +++ V Sbjct: 550 AAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVA 609 Query: 886 EKLPELMKNVAELKVPLLAEVGIGKNWDEAH 916 +++ +LM+N L VPLL EVG G+NWD+AH Sbjct: 610 KQIHQLMENCTRLDVPLLVEVGSGENWDQAH 640 >ZpolA_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains EcZ Escherichia coli O157:H7 EDL933 Length = 640 Score = 713 bits (1840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/631 (59%), Positives = 456/631 (72%), Gaps = 12/631 (1%) Query: 295 GASAAAALEAPAQGGLFAAAPKV--------EYETVLTDAQLDQWIATINAAELTAVDTE 346 GA AA P + + AP+V Y T+L + L WIA + A + A DTE Sbjct: 13 GAKPAAK---PQETSVADEAPEVTATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTE 69 Query: 347 TTSLEAMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSRQHVLEKLKPWLEDASKPKL 406 T SL+ + A LVG+S EPG AAYIPVAH+Y DAP Q+SR+ LE LKP LED K+ Sbjct: 70 TDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKV 129 Query: 407 GQHLKYDSHIFANYGVRLAGVQHDTLLESYVFES-HRPHDMDSLAARHLERKTITYAEVC 465 GQ+LKYD I ANYG+ L G+ DT+LESY+ S HDMDSLA R L+ KTIT+ E+ Sbjct: 130 GQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIA 189 Query: 466 GKGASQIGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEHDDKLRFIYEKIEVPTSVVL 525 GKG +Q+ FN++A+E A YAAEDA+VTL LH MWP ++ ++E IE+P VL Sbjct: 190 GKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVL 249 Query: 526 QKIERNGVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPFNLNSPKQLGEILFGKLELP 585 +IERNGV ID + L S +L R+ E+E++A+++AG+ FNL+S KQL ILF K + Sbjct: 250 SRIERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIK 309 Query: 586 VVKKTASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKSTYTDKLPKMVNPATGRVHT 645 +KKT GAPST EEVL++LA DYPLPKV+L+YRGLAKLKSTYTDKLP M+NP TGRVHT Sbjct: 310 PLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVHT 369 Query: 646 NYAQAVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEGSVIVSADYSQIELRIMAHI 705 +Y QAV TGRLSS DPNLQNIP+R EGRRIR+AF+APE VIVSADYSQIELRIMAH+ Sbjct: 370 SYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHL 429 Query: 706 SEDENMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAKVINFGLIYGMSAFGLASNL 765 S D+ +L AFA +DIHRATAAE+FG+ E V SEQRR AK INFGLIYGMSAFGLA L Sbjct: 430 SRDKGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQL 489 Query: 766 GIERAAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETVFGRRLWLPEINSPNGPRRQ 825 I R AQ Y+D YF R+ GV YM+ TR QAK +GYVET+ GRRL+LP+I S NG RR Sbjct: 490 NIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRA 549 Query: 826 GAERAAINAPMQGTAADLIKMAMIAVQDWLETNSLQTRMIMQVHDELVLEVPQQELEVVR 885 AERAAINAPMQGTAAD+IK AMIAV WL+ + RMIMQVHDELV EV + +++ V Sbjct: 550 AAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHRDDVDAVA 609 Query: 886 EKLPELMKNVAELKVPLLAEVGIGKNWDEAH 916 +++ +LM+N L VPLL EVG G+NWD+AH Sbjct: 610 KQIHQLMENCTRLDVPLLVEVGSGENWDQAH 640 >ECs4786_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains Ecs Escherichia coli O157:H7 Length = 635 Score = 712 bits (1839), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/631 (59%), Positives = 456/631 (72%), Gaps = 12/631 (1%) Query: 295 GASAAAALEAPAQGGLFAAAPKV--------EYETVLTDAQLDQWIATINAAELTAVDTE 346 GA AA P + + AP+V Y T+L + L WIA + A + A DTE Sbjct: 8 GAKPAAK---PQETSVADEAPEVTATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTE 64 Query: 347 TTSLEAMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSRQHVLEKLKPWLEDASKPKL 406 T SL+ + A LVG+S EPG AAYIPVAH+Y DAP Q+SR+ LE LKP LED K+ Sbjct: 65 TDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKV 124 Query: 407 GQHLKYDSHIFANYGVRLAGVQHDTLLESYVFES-HRPHDMDSLAARHLERKTITYAEVC 465 GQ+LKYD I ANYG+ L G+ DT+LESY+ S HDMDSLA R L+ KTIT+ E+ Sbjct: 125 GQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIA 184 Query: 466 GKGASQIGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEHDDKLRFIYEKIEVPTSVVL 525 GKG +Q+ FN++A+E A YAAEDA+VTL LH MWP ++ ++E IE+P VL Sbjct: 185 GKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVL 244 Query: 526 QKIERNGVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPFNLNSPKQLGEILFGKLELP 585 +IERNGV ID + L S +L R+ E+E++A+++AG+ FNL+S KQL ILF K + Sbjct: 245 SRIERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIK 304 Query: 586 VVKKTASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKSTYTDKLPKMVNPATGRVHT 645 +KKT GAPST EEVL++LA DYPLPKV+L+YRGLAKLKSTYTDKLP M+NP TGRVHT Sbjct: 305 PLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVHT 364 Query: 646 NYAQAVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEGSVIVSADYSQIELRIMAHI 705 +Y QAV TGRLSS DPNLQNIP+R EGRRIR+AF+APE VIVSADYSQIELRIMAH+ Sbjct: 365 SYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHL 424 Query: 706 SEDENMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAKVINFGLIYGMSAFGLASNL 765 S D+ +L AFA +DIHRATAAE+FG+ E V SEQRR AK INFGLIYGMSAFGLA L Sbjct: 425 SRDKGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQL 484 Query: 766 GIERAAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETVFGRRLWLPEINSPNGPRRQ 825 I R AQ Y+D YF R+ GV YM+ TR QAK +GYVET+ GRRL+LP+I S NG RR Sbjct: 485 NIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRA 544 Query: 826 GAERAAINAPMQGTAADLIKMAMIAVQDWLETNSLQTRMIMQVHDELVLEVPQQELEVVR 885 AERAAINAPMQGTAAD+IK AMIAV WL+ + RMIMQVHDELV EV + +++ V Sbjct: 545 AAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHRDDVDAVA 604 Query: 886 EKLPELMKNVAELKVPLLAEVGIGKNWDEAH 916 +++ +LM+N L VPLL EVG G+NWD+AH Sbjct: 605 KQIHQLMENCTRLDVPLLVEVGSGENWDQAH 635 >YPO0017_2 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains Ype Yersinia pestis Length = 645 Score = 710 bits (1833), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/643 (55%), Positives = 455/643 (70%), Gaps = 8/643 (1%) Query: 276 WLRELSDGAEAGASKAPMVGASAAAALEAPAQGGLFAAAPKVEYETVLTDAQLDQWIATI 335 WL D S V A A E + A + Y+T+L + L WI + Sbjct: 9 WLDSKKDRPTGQTSSQSFVAADTAPTAE------VTAVLSQENYQTILDEKALADWIERL 62 Query: 336 NAAELTAVDTETTSLEAMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSRQHVLEKLK 395 AAE+ A DTET L+ + L+G+S PG AAY+P+AH+Y DAP QL R VL LK Sbjct: 63 KAAEVFAFDTETDGLDTLSCNLIGMSFAVAPGEAAYLPLAHDYLDAPPQLDRDWVLATLK 122 Query: 396 PWLEDASKPKLGQHLKYDSHIFANYGVRLAGVQHDTLLESYVFES-HRPHDMDSLAARHL 454 P LED K+GQ+LK+D + A YG+ L G+ DT+LESYV +S HDMDSLA R+L Sbjct: 123 PLLEDDKALKVGQNLKFDKSMLARYGIDLKGIAFDTMLESYVLDSVAGRHDMDSLAERYL 182 Query: 455 ERKTITYAEVCGKGASQIGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEHDDKLRFIY 514 KTIT+ E+ GKG +Q+ FN++A+E+A YAAEDA+VTL LH +WP+++ + L+ ++ Sbjct: 183 NHKTITFEEIAGKGKNQLTFNQIALEQAGPYAAEDADVTLQLHLVLWPKLQQSEGLKRVF 242 Query: 515 EKIEVPTSVVLQKIERNGVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPFNLNSPKQL 574 ++IE+P +L +IER GVLID L S +L R+ E+E+QA++LA +PFNL SPKQL Sbjct: 243 QEIEMPLLPILSRIERTGVLIDQNILAAHSKELTIRLDELEKQAHELAEEPFNLASPKQL 302 Query: 575 GEILFGKLELPVVKKTASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKSTYTDKLPK 634 IL+ K +LP++KKT GA ST+EEVL +LA DYPLPKV+L+YRGLAKLKSTYTDKLP Sbjct: 303 QAILYEKQKLPILKKTPGGAASTNEEVLAELALDYPLPKVILEYRGLAKLKSTYTDKLPL 362 Query: 635 MVNPATGRVHTNYAQAVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEGSVIVSADY 694 M+NP +GRVHT+Y QAV TGRLSS DPNLQNIP+R EGRRIR+AF+AP+G I++ADY Sbjct: 363 MINPVSGRVHTSYHQAVTATGRLSSRDPNLQNIPVRNEEGRRIRQAFIAPKGYCIMAADY 422 Query: 695 SQIELRIMAHISEDENMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAKVINFGLIY 754 SQIELRIMAH+S+D +L AFA +DIHRATAAE+FG E+V +EQRR AK INFGLIY Sbjct: 423 SQIELRIMAHLSQDNGLLAAFAAGQDIHRATAAEVFGSPLEKVTTEQRRSAKAINFGLIY 482 Query: 755 GMSAFGLASNLGIERAAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETVFGRRLWLP 814 GMSAFGLA LGI R AQ Y+D YF R+ GV YM+ TR QA +GYV T+ GRRL+LP Sbjct: 483 GMSAFGLARQLGIPRGEAQRYMDLYFERYPGVLEYMERTRKQAAEQGYVTTLDGRRLYLP 542 Query: 815 EINSPNGPRRQGAERAAINAPMQGTAADLIKMAMIAVQDWLETN-SLQTRMIMQVHDELV 873 +I+S N RR+ AER AINAPMQGTAAD+IK AMIAV WL+ R+IMQVHDELV Sbjct: 543 DIHSRNANRRKAAEREAINAPMQGTAADIIKRAMIAVDGWLQQEPEPLVRVIMQVHDELV 602 Query: 874 LEVPQQELEVVREKLPELMKNVAELKVPLLAEVGIGKNWDEAH 916 EV + L+ +K+ ELM+ +L VPL +VG+G NWD+AH Sbjct: 603 FEVHESVLQSAEQKIRELMEQSMQLAVPLKVDVGVGANWDQAH 645