BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0009.p (399 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_srfAB_2 [Q] COG1020 Non-ribosomal peptide synthetase modules ... 194 4e-49 BS_ppsD_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 188 2e-47 BS_dhbF [Q] COG1020 Non-ribosomal peptide synthetase modules and... 186 7e-47 PA2402_1 [Q] COG1020 Non-ribosomal peptide synthetase modules an... 184 4e-46 BS_ppsA_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 184 5e-46 BS_ppsE_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 183 7e-46 PA2402_3 [Q] COG1020 Non-ribosomal peptide synthetase modules an... 182 1e-45 BS_ppsB_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 181 2e-45 BS_ppsC_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 179 7e-45 Rv2380c_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 178 2e-44 >BS_srfAB_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1045 Score = 194 bits (492), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 127/373 (34%), Positives = 194/373 (52%), Gaps = 24/373 (6%) Query: 11 ERFANFLRQHGIDALKIVPSHLDALLETPAPYLPAT------LVLGGEATAPAQLARIRA 64 + A+++++HGI +K+ PS ++ T + A +VLGGE P + R Sbjct: 673 DEIAHYIKEHGITYIKLTPSLFHTIVNTASFAFDANFESLRLIVLGGEKIIPTDVIAFRK 732 Query: 65 LAPQCRIFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLP-LTEALPHAYVRVLDAQL 123 + NHYGPTE T+G + R E D A P + + +A VL+ L Sbjct: 733 MYGHTEFINHYGPTEATIGAIAGRVDL-----YEPDAFAKRPTIGRPIANAGALVLNEAL 787 Query: 124 RPTPAGAIGQLWLGGAQLARGYLDA-QQDREAFIDDPWLPGRRLYRSGDLAVLLPQGGVR 182 + P GA GQL++ G LARGYL+ Q E F+++P+ PG +Y++GD+ L G + Sbjct: 788 KLVPPGASGQLYITGQGLARGYLNRPQLTAERFVENPYSPGSLMYKTGDVVRRLSDGTLA 847 Query: 183 LAGRADHQVKVRGFRIEPGEIEAALRTQPGVRQALVLAAPDGA---LAACLAADHGQALP 239 GRAD QVK+RG+RIE GEIE + + G+++A+VLA +G L A +D Sbjct: 848 FIGRADDQVKIRGYRIELGEIETVMLSLSGIQEAVVLAVSEGGLQELCAYYTSDQDIEKA 907 Query: 240 AWRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPD---SGTPAVVAQAQ 296 R L+ LP+ M P+ ++ + +P NGK DR A L +P+ SG A+ A + Sbjct: 908 ELRYQLSLTLPSHMIPAFFVQVDAIPLTANGKTDRNA----LPKPNAAQSGGKALAA-PE 962 Query: 297 GALAALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLALEAAPALVFDHP 356 AL L + + L AI +++FF+LG HSL + LIA I+ L +F+ P Sbjct: 963 TALEESLCRIWQKTLGIEAIGIDDNFFDLGGHSLKGMMLIANIQAELEKSVPLKALFEQP 1022 Query: 357 NAIALAAALQAAA 369 LAA ++A+A Sbjct: 1023 TVRQLAAYMEASA 1035 >BS_ppsD_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1030 Score = 188 bits (478), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 126/376 (33%), Positives = 182/376 (48%), Gaps = 24/376 (6%) Query: 8 RDGERFANFLRQHGIDALKIVPSHLDALLET----PAPYLPATL---VLGGEATAPAQLA 60 ++ E A + + I A+ VPS L A LE P L GGE ++ Sbjct: 663 KEPEVIAKAIEEQKITAMHFVPSMLHAFLEQIKYRSVPIKTNRLKRVFSGGEQLGTHLVS 722 Query: 61 RIRALAPQCRIFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTEALPHAYVRVLD 120 R L P I N YGPTE TV + E +P+ + + H + +L+ Sbjct: 723 RFYELLPNVSITNSYGPTEATVEAAFFDCPPHEKLE-------RIPIGKPVHHVRLYLLN 775 Query: 121 AQLRPTPAGAIGQLWLGGAQLARGYLDA-QQDREAFIDDPWLPGRRLYRSGDLAVLLPQG 179 R P G IG+L++ GA +ARGYL+ E F++DP+ PG R+Y++GD+A LP G Sbjct: 776 QNQRMLPVGCIGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDG 835 Query: 180 GVRLAGRADHQVKVRGFRIEPGEIEAALRTQPGVRQALVLAAPDGALAACLAADHGQALP 239 V GR D QVK+RG+RIEPGEIEAALR+ GVR+A V D A G Sbjct: 836 NVEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRN 895 Query: 240 AWRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGT---PAVVAQAQ 296 RA L +LP M P+ + + + P +GK+DR AL G D+ T P V + + Sbjct: 896 EVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMK 955 Query: 297 GALAALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLALEAAPALVFDHP 356 L+Q +L+ + +++FF+ G HSL L++RI + ++ VF HP Sbjct: 956 ------LSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRITKEFDVQVPLKDVFAHP 1009 Query: 357 NAIALAAALQAAAPDP 372 LA ++ P Sbjct: 1010 TVEGLATVIREGTDSP 1025 >BS_dhbF [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1278 Score = 186 bits (473), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 136/384 (35%), Positives = 191/384 (49%), Gaps = 21/384 (5%) Query: 1 VASAEDMRDGERFANFLRQHGIDALKIVPSHLDALLETPAPYLPATLVL-GGEATAPAQL 59 +A E +R+ + A + I+ ++ P+ AL+ + L VL GGEA L Sbjct: 675 IAKKETIREPQALAQMIENFDINIMQATPTLWHALVTSEPEKLRGLRVLVGGEALPSGLL 734 Query: 60 ARIRALAPQCRIFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTEALPHAYVRVL 119 ++ L C + N YGPTE T+ AA E + P P+ + + + V VL Sbjct: 735 QELQDL--HCSVTNLYGPTETTIW----SAAAFLEEGLKGVP----PIGKPIWNTQVYVL 784 Query: 120 DAQLRPTPAGAIGQLWLGGAQLARGYLDAQQ-DREAFIDDPWLP-GRRLYRSGDLAVLLP 177 D L+P P G +G+L++ G LARGY E F+ DP+ P G R+YR+GD A Sbjct: 785 DNGLQPVPPGVVGELYIAGTGLARGYFHRPDLTAERFVADPYGPPGTRMYRTGDQARWRA 844 Query: 178 QGGVRLAGRADHQVKVRGFRIEPGEIEAALRTQPGVRQALVLAAP----DGALAACLAAD 233 G + GRADHQ+K+RGFRIE GEI+A L P + QA V+ D LAA + AD Sbjct: 845 DGSLDYIGRADHQIKIRGFRIELGEIDAVLANHPHIEQAAVVVREDQPGDKRLAAYVVAD 904 Query: 234 HGQALPAWRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGTPAVVA 293 R + LP M PS ++ + ELP NGK+DRKA L PD T Sbjct: 905 AAIDTAELRRYMGASLPDYMVPSAFVEMDELPLTPNGKLDRKA----LPAPDFSTSVSDR 960 Query: 294 QAQGALAALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLALEAAPALVF 353 + +L A++L + ++ FFELG HSLL +L++RIR+ + E A +F Sbjct: 961 APRTPQEEILCDLFAEVLGLARVGIDDSFFELGGHSLLAARLMSRIREVMGAELGIAKLF 1020 Query: 354 DHPNAIALAAALQAAAPDPDALER 377 D P LAA L A AL+R Sbjct: 1021 DEPTVAGLAAHLDLAQSACPALQR 1044 >PA2402_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Pae Pseudomonas aeruginosa Length = 1541 Score = 184 bits (466), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 137/377 (36%), Positives = 190/377 (50%), Gaps = 38/377 (10%) Query: 1 VASAEDMRDGERFANFLRQHGIDALKIVPSHLDALLETPAPYLPATL---VLGGEATAPA 57 VA+ D RD + + + G+D L VPS L A L+ +L V GEA Sbjct: 724 VAAPGDHRDPAKLVELINREGVDTLHFVPSMLQAFLQDEDVASCTSLKRIVCSGEALPAD 783 Query: 58 QLARIRALAPQCRIFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTEALPHAYVR 117 ++ A PQ ++N YGPTE + V H E +A +P+ + + Sbjct: 784 AQQQVFAKLPQAGLYNLYGPTEAAIDV-THWTCVEEGKDA-------VPIGRPIANLACY 835 Query: 118 VLDAQLRPTPAGAIGQLWLGGAQLARGY-----LDAQQDREAFIDDPWLPGRRLYRSGDL 172 +LD L P P G +G+L+L G LARGY L A E F+ P++ G R+YR+GDL Sbjct: 836 ILDGNLEPVPVGVLGELYLAGRGLARGYHQRPGLTA----ERFVASPFVAGERMYRTGDL 891 Query: 173 AVLLPQGGVRLAGRADHQVKVRGFRIEPGEIEAALRTQPGVRQALVLAAPDGALAA--CL 230 A G + AGR DHQVK+RG RIE GEIEA L P VR+A VLA L L Sbjct: 892 ARYRADGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHPWVREAAVLAVDGKQLVGYVVL 951 Query: 231 AADHGQALPAWRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGTPA 290 ++ G A A LA LP M P++WL L +P NGK+DRKAL P Sbjct: 952 ESEGGDWREALAAHLATSLPEYMVPAQWLALERMPLSPNGKLDRKAL---------PAPE 1002 Query: 291 V-VAQA-----QGALAALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLA 344 V VAQA + A+ LA+ LL + +++FF LG S++ I++++R RQ+ Sbjct: 1003 VSVAQAGYSAPRNAVERTLAEIWQDLLGVEQVGLDDNFFSLGGDSIVSIQVVSRARQA-G 1061 Query: 345 LEAAPALVFDHPNAIAL 361 L+ +P +F H N +L Sbjct: 1062 LQLSPRDLFQHQNIRSL 1078 >BS_ppsA_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1045 Score = 184 bits (466), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 116/327 (35%), Positives = 170/327 (51%), Gaps = 15/327 (4%) Query: 50 GGEATAPAQLARIRALAPQCRIFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTE 109 GGE AP AR ++ PQ + + YGPTE TV + E + + +P+ + Sbjct: 724 GGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDR-----LRIPIGK 778 Query: 110 ALPHAYVRVLDAQLRPTPAGAIGQLWLGGAQLARGYLDA-QQDREAFIDDPWLPGRRLYR 168 +P A + VLD L P+G G+L++ GA +ARGYL+ E F++DP+ PG R+Y+ Sbjct: 779 PVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYK 838 Query: 169 SGDLAVLLPQGGVRLAGRADHQVKVRGFRIEPGEIEAALRTQPGVRQALVLAAPDGALAA 228 +GD+A LP G V GR D QVK+RG+RIEPGEIEAALR+ GVR+A V D Sbjct: 839 TGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPE 898 Query: 229 CLAADHGQALPAWRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGT 288 A G RA L +LP M P+ + + + P +GK+DR AL G D+ T Sbjct: 899 LCAYVEGLQRNEVRAQLQRLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAET 958 Query: 289 ---PAVVAQAQGALAALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLAL 345 P V + + L+Q +L+ + +++FF+ G HSL L++RI + + Sbjct: 959 YTAPRNVTEMK------LSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDV 1012 Query: 346 EAAPALVFDHPNAIALAAALQAAAPDP 372 + VF HP LA ++ P Sbjct: 1013 QVPLKDVFAHPTVEGLATVIREGTDSP 1039 >BS_ppsE_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1060 Score = 183 bits (464), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 119/363 (32%), Positives = 180/363 (49%), Gaps = 16/363 (4%) Query: 11 ERFANFLRQHGIDALKIVPSHLDALLETPAPYLPA--TLVLGGEATAPAQLARIRALAPQ 68 +RF +L ++ I L + + + L + A TL +GGEA +PA + +R P Sbjct: 696 DRFGAYLLENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHACPD 755 Query: 69 CRIFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTEALPHAYVRVLDAQLRPTPA 128 + N YGPTE T E + D +P+ + + ++ +LD + R P Sbjct: 756 LALHNIYGPTENT--------TFSTFFEMKRDYAGPIPIGKPISNSTAYILDTKGRLLPI 807 Query: 129 GAIGQLWLGGAQLARGYLD-AQQDREAFIDDPWLPGRRLYRSGDLAVLLPQGGVRLAGRA 187 G G+L +GG +A+GYL+ F P+LPG R+YR+GDLA LP G + R Sbjct: 808 GVPGELCVGGDGVAKGYLNRVDLTNAVFSPHPFLPGERIYRTGDLARWLPDGNLEYISRI 867 Query: 188 DHQVKVRGFRIEPGEIEAALRTQPGVRQALV-LAAPDGA--LAACLAADHGQALPAWRAA 244 D Q+K+RG RIEP EIEA L GV++A V L DG L DH + +RA Sbjct: 868 DRQMKIRGKRIEPAEIEARLLEMEGVQEAAVTLREKDGEAQLYTHYVGDHKKTDTDFRAD 927 Query: 245 LAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGTPAVVAQAQGALAALLA 304 LA VLP M P W+ + +P GNGK+DR AL +P ++ + + LA Sbjct: 928 LARVLPDYMIPQHWVRVERMPLTGNGKIDRSALPIPENKPAKRQNIIL--PRNLVEEELA 985 Query: 305 QQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLALEAAPALVFDHPNAIALAAA 364 Q+L I+ ++DFF +G HSL +++I ++ ++ +F+HP LA Sbjct: 986 NIWKQVLGVNTISIDDDFFAIGGHSLRALQVIHTLKHQQNIDIPIDFLFEHPTIAQLAEK 1045 Query: 365 LQA 367 L + Sbjct: 1046 LYS 1048 >PA2402_3 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Pae Pseudomonas aeruginosa Length = 1495 Score = 182 bits (461), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 130/372 (34%), Positives = 185/372 (49%), Gaps = 27/372 (7%) Query: 1 VASAEDMRDGERFANFLRQHGIDALKIVPSHLDALLETPAPYLPATL---VLGGEATAPA 57 VA+ D RD + + + G+D L VPS L A L+ +L V GEA + Sbjct: 671 VAAPGDHRDPAKLVALINREGVDTLHFVPSMLQAFLQDEDVVSCTSLKRIVCSGEALSAD 730 Query: 58 QLARIRALAPQCRIFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTEALPHAYVR 117 ++ A PQ ++N YGPTE + V H + E +A +P+ + + Sbjct: 731 AQQQVFAKLPQAGLYNLYGPTEAAIDV-THWSCVEEGKDA-------VPIGRPIANLGCY 782 Query: 118 VLDAQLRPTPAGAIGQLWLGGAQLARGY-----LDAQQDREAFIDDPWLPGRRLYRSGDL 172 +LD L P P G +G+L+L G LARGY L A E F+ P++ G R+YR+GDL Sbjct: 783 ILDGDLEPVPVGVLGELYLAGRGLARGYHQRPGLTA----ERFVASPFVAGERMYRTGDL 838 Query: 173 AVLLPQGGVRLAGRADHQVKVRGFRIEPGEIEAALRTQPGVRQALVLAAPDGALAA--CL 230 A G + AGR DHQVK+RG RIE GEIEA L P VR+A VLA L L Sbjct: 839 ARYRADGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHPWVREAAVLAVDSRQLVGYVVL 898 Query: 231 AADHGQALPAWRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGTPA 290 ++ G A A LA LP M P++WL L +P NGK+DRKA L RP + Sbjct: 899 ESEGGDWREALAAHLATSLPEYMVPAQWLALERMPLSPNGKLDRKA----LPRPQAAAGQ 954 Query: 291 VVAQAQGALAALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLALEAAPA 350 Q + +A A +L+ + A ++FF LG S++ I++++R R + ++ P Sbjct: 955 THVAPQNEMERRIAAVWADVLKLEEVGATDNFFALGGDSIVSIQVVSRCRAA-GIQFTPK 1013 Query: 351 LVFDHPNAIALA 362 +F LA Sbjct: 1014 DLFQQQTVQGLA 1025 >BS_ppsB_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1050 Score = 181 bits (459), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 122/357 (34%), Positives = 177/357 (49%), Gaps = 22/357 (6%) Query: 19 QHGIDALKIVPSHLDALLETPAPYLPATL---VLGGEATAPAQLARIRALAPQCRIFNHY 75 ++ + + IVPS LLE +L GEA P L + + P + N Y Sbjct: 696 RYKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLELNQIICPSAELANEY 755 Query: 76 GPTECTVGVLVHRAATEAEAEAEADPGASLPLTEALPHAYVRVLDAQLRPTPAGAIGQLW 135 GPTE +V + R + E P + + V VL + P GA G+L Sbjct: 756 GPTENSVATTILRHLNKKERITIGHP---------IRNTKVFVLHGN-QMQPIGAAGELC 805 Query: 136 LGGAQLARGYLDAQQ-DREAFIDDPWLPGRRLYRSGDLAVLLPQGGVRLAGRADHQVKVR 194 + GA LARGY Q+ ++AF D P+L G RLYR+GD LP G + GR D QVK+R Sbjct: 806 ISGAGLARGYYKQQELTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIR 865 Query: 195 GFRIEPGEIEAALRTQPGVRQALVLA----APDGALAACLAADHGQALPAWRAALAEVLP 250 G+RIE EIE LR PGV++A VLA A + L A + + G +LP LA LP Sbjct: 866 GYRIELREIETVLRQAPGVKEAAVLARDVSAEEKELVAYIVPEKGNSLPDLYQHLAGTLP 925 Query: 251 AQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGTPAVVAQAQGALAALLAQQMAQL 310 + M P+ + + ++P +GK+DR AL E P++ T + + A LA + Sbjct: 926 SYMIPASIINISQMPLTSSGKLDRFALPE----PENNTSVTYMAPRTLIEADLAHIWEDV 981 Query: 311 LERPAIAANEDFFELGAHSLLVIKLIARIRQSLALEAAPALVFDHPNAIALAAALQA 367 L + I +DFF+LG SL L++RI + L +E + VF +P ++A L + Sbjct: 982 LNKQHIGIRDDFFQLGGQSLKAAALVSRIHKKLNVELPLSEVFSYPTVESMAVKLMS 1038 >BS_ppsC_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Bsu Bacillus subtilis Length = 1050 Score = 179 bits (455), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 115/327 (35%), Positives = 169/327 (51%), Gaps = 15/327 (4%) Query: 50 GGEATAPAQLARIRALAPQCRIFNHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTE 109 GGE AP AR ++ PQ + + YGPTE TV + E + + +P+ + Sbjct: 730 GGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDR-----LRIPIGK 784 Query: 110 ALPHAYVRVLDAQLRPTPAGAIGQLWLGGAQLARGYLDA-QQDREAFIDDPWLPGRRLYR 168 +P A + VLD L P+G G+L++ GA +ARGYL+ E F++DP+ G R+Y+ Sbjct: 785 PVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYLGERMYK 844 Query: 169 SGDLAVLLPQGGVRLAGRADHQVKVRGFRIEPGEIEAALRTQPGVRQALVLAAPDGALAA 228 +GD+A LP G V GR D QVK+RG+RIEPGEIEAALR+ GVR+A V D Sbjct: 845 TGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPE 904 Query: 229 CLAADHGQALPAWRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGT 288 A G RA L +LP M P+ + + + P +GK+DR AL G D+ T Sbjct: 905 LCAYVEGLQRNEVRAQLQRLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAET 964 Query: 289 ---PAVVAQAQGALAALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLAL 345 P V + + L+Q +L+ + +++FF+ G HSL L++RI + + Sbjct: 965 YTAPRNVTEMK------LSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDV 1018 Query: 346 EAAPALVFDHPNAIALAAALQAAAPDP 372 + VF HP LA ++ P Sbjct: 1019 QVPLKDVFAHPTVEGLATVIREGTDSP 1045 >Rv2380c_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Mtu Mycobacterium tuberculosis H37Rv Length = 1020 Score = 178 bits (451), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 126/372 (33%), Positives = 176/372 (47%), Gaps = 28/372 (7%) Query: 16 FLRQHGIDALKIVPSHLDALLETPAPYLPATLV---LGGEATAPAQLARIRALAPQCRIF 72 LR GI A+ VPS L L P TL +GGE P ++A + Sbjct: 654 LLRDEGITAMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEPL-PGEVADKFHATFDALLH 712 Query: 73 NHYGPTECTVGVLVHRAATEAEAEAEADPGASLPLTEALPHAYVRVLDAQLRPTPAGAIG 132 N YGPTE + + +P+ + + +LD L+P P G IG Sbjct: 713 NFYGPTETVINASRFKVVGPQGTRI-------VPIGRPKINTTMHLLDDSLQPVPTGVIG 765 Query: 133 QLWLGGAQLARGY-LDAQQDREAFIDDPWLPGRRLYRSGDLAVLLPQGGVRLAGRADHQV 191 ++++GG +A GY A E F+ DP+ PG R+YRSGDLA G + GRAD QV Sbjct: 766 EIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNADGDIEFVGRADEQV 825 Query: 192 KVRGFRIEPGEIEAALRTQPGVRQALVLAAPDGALAACLA------------ADHGQALP 239 K+RGFRIE G++ AA+ P V QA+V+ + L L AD G L Sbjct: 826 KIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLD 885 Query: 240 AWRAALAEVLPAQMQPSRWLVLPELPRLGNGKVDRKALLEQLGRPDSGTPAVVAQAQGAL 299 RA +A LP M P+ ++VL E+P +GK+DR AL E P + Q A Sbjct: 886 RIRARVAAALPEYMLPAAYVVLDEIPITAHGKIDRAALPE----PQIASDTEFRAPQTAT 941 Query: 300 AALLAQQMAQLLERPAIAANEDFFELGAHSLLVIKLIARIRQSLALEAAPALVFDHPNAI 359 LAQ +LL R + A++ FF+LG HSLL KL+A +R + ++ +F+ Sbjct: 942 ERRLAQLFGELLGRDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVT 1001 Query: 360 ALAAALQAAAPD 371 ALA + D Sbjct: 1002 ALAGHIDTLDSD 1013