BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0093.p (525 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1411 [GEPR] COG0477 Permeases of the major facilitator superfa... 662 0.0 RSc1852 [GEPR] COG0477 Permeases of the major facilitator superf... 614 e-175 YPO3268 [GEPR] COG0477 Permeases of the major facilitator superf... 437 e-122 RSc1292 [GEPR] COG0477 Permeases of the major facilitator superf... 431 e-120 STM2815 [GEPR] COG0477 Permeases of the major facilitator superf... 420 e-117 emrB [GEPR] COG0477 Permeases of the major facilitator superfami... 416 e-116 ECs3548 [GEPR] COG0477 Permeases of the major facilitator superf... 416 e-116 ZemrB [GEPR] COG0477 Permeases of the major facilitator superfam... 414 e-115 NMA2168 [GEPR] COG0477 Permeases of the major facilitator superf... 396 e-110 NMB0319 [GEPR] COG0477 Permeases of the major facilitator superf... 395 e-109 >VC1411 [GEPR] COG0477 Permeases of the major facilitator superfamily Vch Vibrio cholerae Length = 511 Score = 662 bits (1708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/501 (63%), Positives = 392/501 (78%) Query: 25 PLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAIT 84 PLSG L + LA ANF+A+LDTTIANVSVS IAG+LG STSQGTYVITSYAVAEAI+ Sbjct: 11 PLSGWALFFGALCLAMANFLAILDTTIANVSVSNIAGSLGTSTSQGTYVITSYAVAEAIS 70 Query: 85 VPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQT 144 VPLTGWLA+RFG++RVF+ ++FG+FS LCG+ANS+ L+ FRVL G GGPLMPLSQT Sbjct: 71 VPLTGWLASRFGSIRVFVTCFLLFGVFSLLCGLANSMSTLVMFRVLLGFVGGPLMPLSQT 130 Query: 145 LLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIG 204 L++RIFPK K+ AA+G+W+MTTLVAPI GPILGGVLCDQ SWPYIF+I +P A+ + Sbjct: 131 LMIRIFPKNKSHAAIGIWSMTTLVAPIMGPILGGVLCDQLSWPYIFFIKMPFAIAAALLC 190 Query: 205 WRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFF 264 W++LK++ETK + ID+VGL L+VVWVAALQLMLDEGK+ DWF S+ IV LAV AV+ F Sbjct: 191 WKLLKKFETKTTHSKIDKVGLALLVVWVAALQLMLDEGKDHDWFESSRIVFLAVIAVIGF 250 Query: 265 IAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATW 324 IAFLIWELTERNP+VDL+VFRHRG++ S+ T+ LAFGAFF V+TPLWLQ YMGYTAT Sbjct: 251 IAFLIWELTERNPVVDLKVFRHRGYSISMVTLSLAFGAFFSISVVTPLWLQIYMGYTATI 310 Query: 325 SGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQIGW 384 SG +A GILAV AP+VA +S+ D R V GV WLG TF+R FNT DM+F QI W Sbjct: 311 SGHATASMGILAVFLAPIVANLSSKFDPRPFVFAGVMWLGLWTFMRGFNTVDMTFSQISW 370 Query: 385 PLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWENDAT 444 PLF QGIG+PLFFVPLT +AL SV E SAAGLM+F RT++GA ATS++NTSWE++ Sbjct: 371 PLFFQGIGMPLFFVPLTAIALGSVKPHEMESAAGLMNFIRTLSGAFATSMINTSWEHETR 430 Query: 445 YFHAELSGLVDRGGDAINTMMASGMSAEQATASLAQTVQNQAVMLSTNHIFMMAAVSFSL 504 Y HAEL+GL D+ G A M SGMSAEQ +++ +QNQ+VM++TN +F++ A+ F Sbjct: 431 YVHAELAGLTDKAGVATQAMQNSGMSAEQTRSAMDWILQNQSVMVATNQLFIVIALIFVF 490 Query: 505 AALAVWLAPKPTRVADTSAAH 525 AA +W APKP + DTSA H Sbjct: 491 AACMIWFAPKPKQAVDTSAVH 511 >RSc1852 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 512 Score = 614 bits (1583), Expect = e-175, Method: Compositional matrix adjust. Identities = 310/504 (61%), Positives = 387/504 (76%), Gaps = 1/504 (0%) Query: 23 EAPLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEA 82 +APL+GG L A I+LAAANF+AVLD TIANVSV I+G LG STSQGT+VITSYAVAEA Sbjct: 9 QAPLTGGMLWLAAIVLAAANFVAVLDMTIANVSVPNISGNLGVSTSQGTWVITSYAVAEA 68 Query: 83 ITVPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLS 142 I VPLTGWLA+RFGTVRVF ++M FGLFSALCG+A SLGML+A R+ QGLAGGPLMPLS Sbjct: 69 ILVPLTGWLASRFGTVRVFAVAMGCFGLFSALCGLALSLGMLVAARICQGLAGGPLMPLS 128 Query: 143 QTLLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGY 202 QTLLLRIFPKEKA AA+GLW+MTT+VAP+ GPILGG LCD+YSWP+IF+IN+P+A+ C + Sbjct: 129 QTLLLRIFPKEKAGAAIGLWSMTTIVAPVLGPILGGYLCDEYSWPWIFYINLPIAVGCAW 188 Query: 203 IGWRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVV 262 W+ML RYE+ +++ PID+VGL L+V+WV +LQ+MLDEGK+ DWFAS+ I LAV A + Sbjct: 189 AAWKMLARYESPIARNPIDKVGLALLVLWVGSLQIMLDEGKQLDWFASSTIAGLAVVAAI 248 Query: 263 FFIAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTA 322 F AFLIWEL +P V+LRVFRHRGF+ASV TI LAFGAFFG+ VLTP WLQ +MGYTA Sbjct: 249 GFAAFLIWELHAEHPAVNLRVFRHRGFSASVLTISLAFGAFFGANVLTPQWLQSFMGYTA 308 Query: 323 TWSGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQI 382 +G +A +G A+ AP+ A + +DARKLV GV WLG IT R TTDM+++Q+ Sbjct: 309 LEAGKTTAWSGFFALFAAPIAAGLGGKVDARKLVFGGVIWLGIITLWRTVATTDMTYWQV 368 Query: 383 GWPLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWEND 442 PL G+G+P FFVP TGLA++SV+EEE ASAAGLM+F RT++GA ATS++ T W++ Sbjct: 369 AVPLMAMGLGIPFFFVPTTGLAMASVDEEEMASAAGLMNFLRTLSGAFATSLITTLWDDR 428 Query: 443 ATYFHAELSGLVDRGGDAINTMMASGMSAEQATASLAQTVQNQAVMLSTNHIFMMAAVSF 502 AT HAEL G+ D G + +G + + S+ Q + +Q+VML+TN I V+F Sbjct: 429 ATLHHAELVGVSDGDGSVRTMLEGAGSTLDAINQSIDQLLTSQSVMLATNDIMAWVGVAF 488 Query: 503 SLAALAVWLAPKPTR-VADTSAAH 525 LAA A+WLAPKP R VA + H Sbjct: 489 VLAASAIWLAPKPRRTVAPGTGGH 512 >YPO3268 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 511 Score = 437 bits (1124), Expect = e-122, Method: Compositional matrix adjust. Identities = 234/509 (45%), Positives = 320/509 (62%), Gaps = 6/509 (1%) Query: 23 EAPLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEA 82 + PL G L + L+ A F+ VLD+TIANV++ TIAG LG+S SQGT+VITS+ VA A Sbjct: 3 QKPLEGAPLAWMTVALSLATFMQVLDSTIANVAIPTIAGDLGSSNSQGTWVITSFGVANA 62 Query: 83 ITVPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLS 142 I++P+TGWLA R G VR+F+ S +F L S LCGM+NSLGMLI FRV+QGL GPL+PLS Sbjct: 63 ISIPVTGWLAKRVGEVRLFLWSTGLFVLASWLCGMSNSLGMLIFFRVIQGLVAGPLIPLS 122 Query: 143 QTLLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGY 202 Q+LLL +P K A+ LW+MT +VAPI GPILGG + D Y W +IF+IN+P+ L+ Sbjct: 123 QSLLLNNYPPAKRSMALALWSMTIVVAPIFGPILGGYISDNYHWGWIFFINIPIGLVVVL 182 Query: 203 IGWRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVV 262 + LK ETK PID +GLVL+VV + ALQ+MLD+GKE DWF STEI++L V AVV Sbjct: 183 LAGSTLKGRETKTEIRPIDTIGLVLLVVGIGALQIMLDQGKELDWFNSTEIIVLTVVAVV 242 Query: 263 FFIAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTA 322 ++WELT+ +P++DL +F+ R FT + LA+ +FG++VL P LQ GYTA Sbjct: 243 AITFLIVWELTDDHPVIDLSLFKSRNFTIGCLCLSLAYMLYFGAIVLLPQLLQEVYGYTA 302 Query: 323 TWSGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFN-TTDMSFFQ 381 TW+G SA GIL V+ +P++ + + ID R+LV + RA+ M F Sbjct: 303 TWAGLASAPVGILPVLLSPLIGRFAHRIDMRQLVTFSFIMYAVCFYWRAYTFEPGMDFGA 362 Query: 382 IGWPLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWEN 441 WP F QG + FF+PLT + LS + E A+A+ L +F RT+AG+I TSI T W Sbjct: 363 SAWPQFFQGFAIACFFMPLTTITLSGLPPERMAAASSLSNFMRTLAGSIGTSITTTLWTQ 422 Query: 442 DATYFHAELSGLVD----RGGDAINTMMASGMSAEQATASLAQTVQNQAVMLSTNHIFMM 497 + HA+L+ V+ A + GMS +QA+A LA+ + NQ +++S N IF + Sbjct: 423 RESLHHAQLTEFVNPYNPNATQAYQELEKLGMSQQQASAYLAREITNQGLIISANEIFWL 482 Query: 498 AAVSFSLAALAVWLAPKP-TRVADTSAAH 525 +A F + +W A P T AH Sbjct: 483 SAGVFLMLLALIWFARPPFTSGGGGGGAH 511 >RSc1292 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 518 Score = 431 bits (1107), Expect = e-120, Method: Compositional matrix adjust. Identities = 227/507 (44%), Positives = 324/507 (63%), Gaps = 14/507 (2%) Query: 19 PAPFEAPLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYA 78 P P + PL+G +L + L+ A F+ VLD++IANVS+ I+G LG + +QGT+VITS+A Sbjct: 6 PRPLQ-PLTGAKLAIGTVALSLATFMNVLDSSIANVSIPAISGDLGVAPNQGTWVITSFA 64 Query: 79 VAEAITVPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPL 138 VA AI+VPLTGWL RFG VR+F+ S+++F L S CG+A ++G LIA R+LQG GP+ Sbjct: 65 VANAISVPLTGWLTQRFGQVRLFVTSILLFVLSSWACGLAPNMGTLIAARILQGAVAGPM 124 Query: 139 MPLSQTLLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVAL 198 +PLSQ+LLL +P K+ A+ LW MTTLVAPI GPI GG + D +WP+IF+IN+PV + Sbjct: 125 IPLSQSLLLSTYPPAKSSMALALWGMTTLVAPIMGPIFGGWISDNMTWPWIFYINIPVGI 184 Query: 199 ICGYIGWRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAV 258 + Y W + K E+ LPIDR+GL L+V+WV +LQLMLD GKE DWF S EIV L V Sbjct: 185 LAAYATWVIYKDRESPTRALPIDRIGLALLVIWVGSLQLMLDRGKELDWFNSAEIVTLTV 244 Query: 259 TAVVFFIAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYM 318 AVV F FL+WELTE +P+VDL +F+ R F+A V I +A+G FFG++V+ PLWLQ + Sbjct: 245 VAVVGFAFFLVWELTEDHPVVDLTLFKGRNFSAGVVAISVAYGLFFGNLVILPLWLQTIV 304 Query: 319 GYTATWSGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFNTTDMS 378 GYTAT +G + A GI A++ +P++ K +DAR + + ++R+ T + Sbjct: 305 GYTATDAGLVMAPVGIFAILLSPVIGKNLPKMDARWVATTAFITFALVFWMRSRFTIQVD 364 Query: 379 FFQIGWPLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTS 438 + + P +QG + +FF+PLT + LS + E +A+GL +F R M G I SI T Sbjct: 365 TWTLMVPTLIQGAAMAMFFIPLTSIILSGLRPERIPAASGLSNFVRIMFGGIGASISTTV 424 Query: 439 WENDATYFHAELSGLVDRGGDAINTMMAS--------GMSAEQATASLAQTVQNQAVMLS 490 W+N + HA+ LV+R + N AS GM + QA ++ + + QA M+ Sbjct: 425 WDNRSALHHAQ---LVER-ANPYNPAYASSLGDYTQMGMPSLQANGAIERIISQQAAMMG 480 Query: 491 TNHIFMMAAVSFSLAALAVWLAPKPTR 517 N IF ++AV F + +WL +P + Sbjct: 481 ANDIFWISAVLFIVLIALIWLT-RPAK 506 >STM2815 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 512 Score = 420 bits (1079), Expect = e-117, Method: Compositional matrix adjust. Identities = 225/498 (45%), Positives = 313/498 (62%), Gaps = 5/498 (1%) Query: 23 EAPLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEA 82 + PL G QLV I L+ A F+ VLD+TIANV++ TIAG LG+S SQGT+VITS+ VA A Sbjct: 4 QKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANA 63 Query: 83 ITVPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLS 142 I++PLTGWLA RFG V++F+ S V F S CG+++SL MLI FRV+QG+ GPL+PLS Sbjct: 64 ISIPLTGWLAKRFGEVKLFMWSTVAFAAASWACGVSSSLNMLIFFRVVQGVVAGPLIPLS 123 Query: 143 QTLLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGY 202 Q+LLL +P K A+ LW+MT +VAPI GPILGG + D Y W +IF+INVP+ + Sbjct: 124 QSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGIAVVL 183 Query: 203 IGWRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVV 262 + L+ ET + ID VGL L+V+ + +LQ+MLD GKE DWF+S EI++L V AV+ Sbjct: 184 MTLHTLRGRETHTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVI 243 Query: 263 FFIAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTA 322 ++WELT+ +PIVDL +F+ R FT I LA+ +FG++VL P LQ GYTA Sbjct: 244 AISFLIVWELTDDHPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTA 303 Query: 323 TWSGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFN-TTDMSFFQ 381 TW+G SA GI+ V+ +P++ + + +D R+LV + RA+ M F Sbjct: 304 TWAGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAWTFEPGMDFGA 363 Query: 382 IGWPLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWEN 441 WP F+QG + FF+PLT + LS + E A+A+ L +F RT+AG+I TSI T W + Sbjct: 364 SAWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTD 423 Query: 442 DATYFHAELSGLVDRGGDAINTMMAS----GMSAEQATASLAQTVQNQAVMLSTNHIFMM 497 + HA+L+ V TM GM+ +QA+ +AQ + NQ +++S N IF M Sbjct: 424 RESLHHAQLTESVTAYNPNAQTMYDKLEGLGMTHQQASGWIAQQITNQGLIISANEIFWM 483 Query: 498 AAVSFSLAALAVWLAPKP 515 +A F + VW A P Sbjct: 484 SAGIFLVLLGLVWFAKPP 501 >emrB [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 512 Score = 416 bits (1069), Expect = e-116, Method: Compositional matrix adjust. Identities = 225/498 (45%), Positives = 316/498 (63%), Gaps = 5/498 (1%) Query: 23 EAPLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEA 82 + PL G QLV I L+ A F+ VLD+TIANV++ TIAG LG+S SQGT+VITS+ VA A Sbjct: 4 QKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANA 63 Query: 83 ITVPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLS 142 I++PLTGWLA R G V++F+ S + F + S CG+++SL MLI FRV+QG+ GPL+PLS Sbjct: 64 ISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLS 123 Query: 143 QTLLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGY 202 Q+LLL +P K A+ LW+MT +VAPI GPILGG + D Y W +IF+INVP+ + Sbjct: 124 QSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVL 183 Query: 203 IGWRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVV 262 + + L+ ET+ + ID VGL L+V+ + +LQ+MLD GKE DWF+S EI++L V AVV Sbjct: 184 MTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVV 243 Query: 263 FFIAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTA 322 ++WELT+ NPIVDL +F+ R FT I LA+ +FG++VL P LQ GYTA Sbjct: 244 AICFLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTA 303 Query: 323 TWSGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFN-TTDMSFFQ 381 TW+G SA GI+ V+ +P++ + + +D R+LV + RA+ M F Sbjct: 304 TWAGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGA 363 Query: 382 IGWPLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWEN 441 WP F+QG + FF+PLT + LS + E A+A+ L +F RT+AG+I TSI T W N Sbjct: 364 SAWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTN 423 Query: 442 DATYFHAELSGLVDRGGDAINTMMAS----GMSAEQATASLAQTVQNQAVMLSTNHIFMM 497 + HA+L+ V+ M + GM+ +QA+ +AQ + NQ +++S N IF M Sbjct: 424 RESMHHAQLTESVNPFNPNAQAMYSQLEGLGMTQQQASGWIAQQITNQGLIISANEIFWM 483 Query: 498 AAVSFSLAALAVWLAPKP 515 +A F + VW A P Sbjct: 484 SAGIFLVLLGLVWFAKPP 501 >ECs3548 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 512 Score = 416 bits (1069), Expect = e-116, Method: Compositional matrix adjust. Identities = 225/498 (45%), Positives = 316/498 (63%), Gaps = 5/498 (1%) Query: 23 EAPLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEA 82 + PL G QLV I L+ A F+ VLD+TIANV++ TIAG LG+S SQGT+VITS+ VA A Sbjct: 4 QKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANA 63 Query: 83 ITVPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLS 142 I++PLTGWLA R G V++F+ S + F + S CG+++SL MLI FRV+QG+ GPL+PLS Sbjct: 64 ISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLS 123 Query: 143 QTLLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGY 202 Q+LLL +P K A+ LW+MT +VAPI GPILGG + D Y W +IF+INVP+ + Sbjct: 124 QSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVL 183 Query: 203 IGWRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVV 262 + + L+ ET+ + ID VGL L+V+ + +LQ+MLD GKE DWF+S EI++L V AVV Sbjct: 184 MTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVV 243 Query: 263 FFIAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTA 322 ++WELT+ NPIVDL +F+ R FT I LA+ +FG++VL P LQ GYTA Sbjct: 244 AICFLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTA 303 Query: 323 TWSGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFN-TTDMSFFQ 381 TW+G SA GI+ V+ +P++ + + +D R+LV + RA+ M F Sbjct: 304 TWAGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGA 363 Query: 382 IGWPLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWEN 441 WP F+QG + FF+PLT + LS + E A+A+ L +F RT+AG+I TSI T W N Sbjct: 364 SAWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTN 423 Query: 442 DATYFHAELSGLVDRGGDAINTMMAS----GMSAEQATASLAQTVQNQAVMLSTNHIFMM 497 + HA+L+ V+ M + GM+ +QA+ +AQ + NQ +++S N IF M Sbjct: 424 RESMHHAQLTESVNPFNPNAQAMYSQLEGLGMTQQQASGWIAQQITNQGLIISANEIFWM 483 Query: 498 AAVSFSLAALAVWLAPKP 515 +A F + VW A P Sbjct: 484 SAGIFLVLLGLVWFAKPP 501 >ZemrB [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 512 Score = 414 bits (1065), Expect = e-115, Method: Compositional matrix adjust. Identities = 225/498 (45%), Positives = 316/498 (63%), Gaps = 5/498 (1%) Query: 23 EAPLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEA 82 + PL G QLV I L+ A F+ VLD+TIANV++ TIAG LG+S SQGT+VITS+ VA A Sbjct: 4 QKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANA 63 Query: 83 ITVPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLS 142 I++PLTGWLA R G V++F+ S + F + S CG+++SL MLI FRV+QG+ GPL+PLS Sbjct: 64 ISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLS 123 Query: 143 QTLLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGY 202 Q+LLL +P K A+ LW+MT +VAPI GPILGG + D Y W +IF+INVP+ + Sbjct: 124 QSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVL 183 Query: 203 IGWRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVV 262 + + L+ ET+ + ID VGL L+V+ + +LQ+MLD GKE DWF+S EI++L V AVV Sbjct: 184 MTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDXGKELDWFSSQEIIILTVVAVV 243 Query: 263 FFIAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTA 322 ++WELT+ NPIVDL +F+ R FT I LA+ +FG++VL P LQ GYTA Sbjct: 244 AICFLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTA 303 Query: 323 TWSGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFN-TTDMSFFQ 381 TW+G SA GI+ V+ +P++ + + +D R+LV + RA+ M F Sbjct: 304 TWAGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFXFIMYAVCFYWRAYTFEPGMDFGA 363 Query: 382 IGWPLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWEN 441 WP F+QG + FF+PLT + LS + E A+A+ L +F RT+AG+I TSI T W N Sbjct: 364 SAWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTN 423 Query: 442 DATYFHAELSGLVDRGGDAINTMMAS----GMSAEQATASLAQTVQNQAVMLSTNHIFMM 497 + HA+L+ V+ M + GM+ +QA+ +AQ + NQ +++S N IF M Sbjct: 424 RESMHHAQLTESVNPFNPNAQAMYSQLEGLGMTQQQASGWIAQQITNQGLIISANEIFWM 483 Query: 498 AAVSFSLAALAVWLAPKP 515 +A F + VW A P Sbjct: 484 SAGIFLVLLGLVWFAKPP 501 >NMA2168 [GEPR] COG0477 Permeases of the major facilitator superfamily NmA Neisseria meningitidis Z2491 Length = 516 Score = 396 bits (1018), Expect = e-110, Method: Compositional matrix adjust. Identities = 212/495 (42%), Positives = 298/495 (60%), Gaps = 4/495 (0%) Query: 25 PLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAIT 84 PL G L + L A F+ VLDTTIANV+V IAG LGA+T+QGT+VITS+AVA A++ Sbjct: 13 PLKGAALAWVTLSLGLAVFMEVLDTTIANVAVPVIAGNLGAATTQGTWVITSFAVANAVS 72 Query: 85 VPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQT 144 VPLTG+LA R G V++F + V F + S LCG+A +L L+ FR+LQG GPL+PLSQ+ Sbjct: 73 VPLTGFLAKRIGEVKLFTAAAVGFVITSWLCGIAPNLQSLVVFRILQGFIAGPLIPLSQS 132 Query: 145 LLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIG 204 LL+ +P K A+ LWAMT +VAP+ GPILGG + + W +IF+IN+P+ +I +I Sbjct: 133 LLMASYPPAKRTLALALWAMTVVVAPVLGPILGGWISGNWHWGWIFFINIPIGIISAWIT 192 Query: 205 WRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFF 264 W+ LK ET+ K+P D VGL LMVV + ALQ+MLD GKE DWFAS EI+ L V A+V Sbjct: 193 WKHLKCRETETVKMPTDYVGLTLMVVGIGALQMMLDRGKELDWFASGEIITLGVVALVCL 252 Query: 265 IAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATW 324 F++WEL E+ PIVDL +F+ R FT + L F + G++ L PL LQ +GYT+TW Sbjct: 253 SYFIVWELGEKYPIVDLSLFKDRNFTVGIIATSLGFMVYMGTLTLLPLVLQTNLGYTSTW 312 Query: 325 SGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQIGW 384 +G +A GIL V +P++ + ID R LV F + R DM + W Sbjct: 313 AGLAAAPVGILPVFLSPLIGRFGNKIDMRLLVTASFLTFAFTFYWRTDFYADMDIGNVIW 372 Query: 385 PLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWENDAT 444 P F QG+G+ +FF+PLT + LS + + A+A L +F R + G + S+V+T WE Sbjct: 373 PQFWQGVGVAMFFLPLTTITLSHMKGGQIAAAGSLSNFLRVLMGGVGVSVVSTLWERREA 432 Query: 445 YFHAELSGLVDRGGDAINTMMA----SGMSAEQATASLAQTVQNQAVMLSTNHIFMMAAV 500 H + + ++ A G+S Q + T+ Q ++ +N IFM ++ Sbjct: 433 LHHTRFAEHITPYSATLHETAAHLSQHGVSDIQTLGIINNTITQQGFIIGSNEIFMAGSL 492 Query: 501 SFSLAALAVWLAPKP 515 F + +WLA P Sbjct: 493 LFIIMIPVIWLAKPP 507 >NMB0319 [GEPR] COG0477 Permeases of the major facilitator superfamily Nme Neisseria meningitidis MC58 Length = 508 Score = 395 bits (1015), Expect = e-109, Method: Compositional matrix adjust. Identities = 211/495 (42%), Positives = 297/495 (60%), Gaps = 4/495 (0%) Query: 25 PLSGGQLVGAGILLAAANFIAVLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAIT 84 PL G L + L A F+ VLDTTIANV+V IAG LGA+T+QGT+VITS++VA A++ Sbjct: 5 PLKGAALAWVTLSLGLAVFMEVLDTTIANVAVPVIAGNLGAATTQGTWVITSFSVANAVS 64 Query: 85 VPLTGWLANRFGTVRVFILSMVMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQT 144 VPLTG+LA R G V++F + V F + S LCG+A +L L+ FR+LQG GPL+PLSQ+ Sbjct: 65 VPLTGFLAKRIGEVKLFTAAAVGFVITSWLCGIAPNLQSLVVFRILQGFIAGPLIPLSQS 124 Query: 145 LLLRIFPKEKAPAAVGLWAMTTLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIG 204 LL+ +P K A+ LWAMT +VAP+ GPILGG + + W +IF+IN+P+ +I +I Sbjct: 125 LLMASYPPAKRTLALALWAMTVVVAPVLGPILGGWISGNWHWGWIFFINIPIGIISAWIT 184 Query: 205 WRMLKRYETKMSKLPIDRVGLVLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFF 264 W+ LK ET+ K+P D VGL LMVV + ALQ+MLD GKE DWFAS EI+ L V A+V Sbjct: 185 WKHLKYRETETVKMPTDYVGLTLMVVGIGALQMMLDRGKELDWFASGEIITLGVVALVCL 244 Query: 265 IAFLIWELTERNPIVDLRVFRHRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATW 324 F++WEL E+ PIVDL +F+ R FT V L F + G++ L PL LQ +GYT+TW Sbjct: 245 SYFIVWELGEKYPIVDLSLFKDRNFTVGVIATSLGFMVYMGTLTLLPLVLQTNLGYTSTW 304 Query: 325 SGCISALTGILAVMTAPMVAKMSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQIGW 384 +G +A GIL V +P++ + ID R V F + R DM + W Sbjct: 305 AGLAAAPVGILPVFLSPLIGRFGNKIDMRLFVTASFLTFAFTFYWRTDFYADMDIGNVIW 364 Query: 385 PLFLQGIGLPLFFVPLTGLALSSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWENDAT 444 P F QG+G+ +FF+PLT + LS + + A+A L +F R + G + S+V+T WE Sbjct: 365 PQFWQGVGVAMFFLPLTTITLSHMKGGQIAAAGSLSNFLRVLMGGVGVSVVSTLWERREA 424 Query: 445 YFHAELSGLVDRGGDAINTMMA----SGMSAEQATASLAQTVQNQAVMLSTNHIFMMAAV 500 H + + ++ A G+S Q + T+ Q ++ +N IFM ++ Sbjct: 425 LHHTRFAEHITPYSATLHETAAHLSQHGVSDIQTLGIINNTITQQGFIIGSNEIFMAGSL 484 Query: 501 SFSLAALAVWLAPKP 515 F + +WLA P Sbjct: 485 LFIIMIPVIWLAKPP 499