BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0077.p (345 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll3840 [R] COG1752 Predicted esterase of the alpha-beta hydrola... 287 3e-77 RSc2551 [R] COG1752 Predicted esterase of the alpha-beta hydrola... 260 4e-69 CC3383 [R] COG1752 Predicted esterase of the alpha-beta hydrolas... 254 1e-67 mlr3635 [R] COG1752 Predicted esterase of the alpha-beta hydrola... 89 1e-17 mlr2398 [R] COG1752 Predicted esterase of the alpha-beta hydrola... 88 3e-17 slr0060 [R] COG1752 Predicted esterase of the alpha-beta hydrola... 85 2e-16 RSp1060 [R] COG1752 Predicted esterase of the alpha-beta hydrola... 83 1e-15 PA3241 [R] COG1752 Predicted esterase of the alpha-beta hydrolas... 67 6e-11 >mll3840 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Mlo Mesorhizobium loti Length = 376 Score = 287 bits (734), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 146/346 (42%), Positives = 208/346 (60%), Gaps = 13/346 (3%) Query: 1 VTEEKDIMSNKIISLALQGGGSHGAFTWGVLDRLLEDGRLGFEGISGASAGAMNAVVLAQ 60 +T+ NK I++ALQGGGSHGAF+WGVLDRLLEDGRL +SG SAGAMNAV LA Sbjct: 1 MTKNGKAEENKKINIALQGGGSHGAFSWGVLDRLLEDGRLEISAVSGTSAGAMNAVALAD 60 Query: 61 GYVQDGREGARAALERFWTALSTGAPLDYIN------AEGAPVIANPTPMPGMQALLAMT 114 G+V+ G +GAR L+ FW A++ + A G I N PG M+ Sbjct: 61 GFVRGGVDGARQKLDDFWRAVAAKGRFSPVQRMPWDVAWGNWSIEN---TPGYVFFDTMS 117 Query: 115 RFFSPTQLNPLDINPLRDILLEQVDFDRLRRQRELKLFIAATQVSTGTLKIFRNADLSVE 174 R FSP NPL +NPLRD++ +++DF +R + ++LFI+AT V TG L++F + ++ ++ Sbjct: 118 RVFSPYVANPLGLNPLRDVVAQEIDFKNVRACKSMELFISATNVETGQLRVFSDGEIDLD 177 Query: 175 ALLASACLPSLHRPIEIEGEAYWDGGLTANPPIFPLLHACAARDVMVVLLHPSRRAGTPT 234 ++ASACLP L R +EI+G YWDGG NP ++P A DV++V ++P R GTP Sbjct: 178 TVMASACLPQLFRAVEIKGVPYWDGGYGGNPALYPFFKTAATEDVLLVQINPVVREGTPR 237 Query: 235 STHDIGQRLSEISFSSAFFTELSALALAKREAENSTLAFGSLERRLRQLNMHMIDANELM 294 S ++I R+ EI+F++ E ++A K L G R + MH IDA+E Sbjct: 238 SANEIQNRIDEITFNAGLLREFRSIAFVKELIAAGRLPHGE----YRDIRMHRIDADEAF 293 Query: 295 EQLTNLSKLNTQASFIGSLFQQGRERAAEWLEQNFAQVGHASTFDL 340 + L+ SK+N + +F+ L GR A++WLE+N+ VG T DL Sbjct: 294 KDLSASSKVNAEWAFLTYLRDLGRTAASDWLEENYDAVGKRPTLDL 339 >RSc2551 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Rso Ralstonia solanacearum Length = 349 Score = 260 bits (664), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 139/335 (41%), Positives = 201/335 (60%), Gaps = 7/335 (2%) Query: 11 KIISLALQGGGSHGAFTWGVLDRLLEDGRLGFEGISGASAGAMNAVVLAQGYVQDGREGA 70 K I+LALQGGG+HGAFTWGVLD LLEDGRL FEG+SG SAG+MNAVV+ G ++ G E A Sbjct: 7 KHINLALQGGGAHGAFTWGVLDALLEDGRLSFEGLSGTSAGSMNAVVMLDGLLEGGPERA 66 Query: 71 RAALERFWTALST-GAPLDYINAEGAPVIAN----PTPMPGMQALLAMTRFFSPTQLNPL 125 R L FW A+ST G+P + +++ P P + + S T Sbjct: 67 REKLHAFWLAVSTAGSPFSTMGENAKTLLSGRPFFPDSWPVADWMRMWDSWISATTQGA- 125 Query: 126 DINPLRDILLEQVDFDRLRRQRELKLFIAATQVSTGTLKIFRNADLSVEALLASACLPSL 185 NPLRD+L QVDFDRLR + KLF+AAT V+TG +++F ++ VE +LASACLP L Sbjct: 126 HYNPLRDLLANQVDFDRLRACPDTKLFLAATDVNTGNVRVFGTPEIDVEVVLASACLPYL 185 Query: 186 HRPIEIEGEAYWDGGLTANPPIFPLLHACAARDVMVVLLHPSRRAGTPTSTHDIGQRLSE 245 + IEI+ YWDGG NP +FP + +D+++V ++P R P H++ +RL+E Sbjct: 186 YPAIEIDRHHYWDGGYMGNPVLFPFFYETKTQDILLVHVNPIVRKDVPDQPHEVMERLNE 245 Query: 246 ISFSSAFFTELSALALAKREAENSTLAFGSLERRLRQLNMHMIDANELMEQLTNLSKLNT 305 I+F+++ E+ A+A ++ L RL+ + +H I A+ + L++ +KL T Sbjct: 246 ITFNASLLREMRAIAFVQKLIAEDWLK-PEYRDRLKYIYLHAIRADRPLGDLSSSTKLVT 304 Query: 306 QASFIGSLFQQGRERAAEWLEQNFAQVGHASTFDL 340 SF+ L ++GR+ A WL ++F VG T D+ Sbjct: 305 DWSFLTMLKERGRQEAKLWLRKHFDDVGRNGTVDI 339 >CC3383 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Ccr Caulobacter vibrioides Length = 353 Score = 254 bits (650), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 140/341 (41%), Positives = 204/341 (59%), Gaps = 11/341 (3%) Query: 13 ISLALQGGGSHGAFTWGVLDRLLEDGRLGFEGISGASAGAMNAVVLAQGYVQDGREGARA 72 +SLALQGGG+HGAF WGVLDRLLE+ L ++ ASAGAMNAV LAQG + +GR GARA Sbjct: 16 LSLALQGGGAHGAFEWGVLDRLLEEDDLEIRAVTAASAGAMNAVCLAQGLIDEGRAGARA 75 Query: 73 ALERFWTALSTGAPLD-------YINAEGAPV-IANPTPMPGMQALLAMTRFFSPTQLNP 124 LE FW ++ + + NA G V TP M LA++ SP + NP Sbjct: 76 RLESFWRNVNRAGGRNVFGDTGIWTNAFGGGVDWLKNTPGWRMAETLALS--LSPYEFNP 133 Query: 125 LDINPLRDILLEQVDFDRLRRQRELKLFIAATQVSTGTLKIFRNADLSVEALLASACLPS 184 ++NPL D+L ++ F R+R +KL+I+ATQ+ T K+FR +L+ ++ASACLP Sbjct: 134 FNLNPLHDVLEGEITFSRIRDASPIKLYISATQIRTSKSKVFRETELTSRHIMASACLPQ 193 Query: 185 LHRPIEIEGEAYWDGGLTANPPIFPLLHACAARDVMVVLLHPSRRAGTPTSTHDIGQRLS 244 L + +EI+GE YWDGG ANPP++PL + D+++V L+P R TP S +I RL+ Sbjct: 194 LFQAVEIDGEPYWDGGYLANPPLWPLFYDDTPDDILIVTLNPFVREETPKSPGEIMDRLN 253 Query: 245 EISFSSAFFTELSALALAKREAENSTLAFGSLERRLRQLNMHMIDANELMEQLTNLSKLN 304 EI+F+++ +EL A+ ++ + L + R R++ +H I A++ + L+ +K N Sbjct: 254 EITFNASLVSELRAIGFVQKLLDEGLLK-DNARGRYRRMLVHAITADKPLADLSMSTKFN 312 Query: 305 TQASFIGSLFQQGRERAAEWLEQNFAQVGHASTFDLGRFLP 345 T+ SF+ L +GR A WL+ VG S+ DL P Sbjct: 313 TEWSFLTDLKDRGRAAAQVWLDDCGDCVGVKSSVDLKVGFP 353 >mlr3635 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Mlo Mesorhizobium loti Length = 361 Score = 89.0 bits (219), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 98/348 (28%), Positives = 143/348 (41%), Gaps = 55/348 (15%) Query: 15 LALQGGGSHGAFTWGVLDRLLEDGRLGFEGISGASAGAMNAVVLAQGYVQDGREGAR--A 72 + QGGG+ GA+ GV + L D +SG S GA+NA ++A G E +R Sbjct: 1 MVFQGGGALGAYQAGVY-QALADAGCEPSWLSGVSIGAINASIIA------GNEPSRRLQ 53 Query: 73 ALERFWTALSTGAPLDYINAEGAPV--IANPTPMPGMQALLAMTRFFSPTQLNP------ 124 LE+FW +S G + EG I N T M + FF P NP Sbjct: 54 RLEQFWQTIS-GRKIWSYTPEGDIYRDIRNRTS-SWMTMTMGQPGFFKPRNPNPWFEPQG 111 Query: 125 -------LDINPLRDILLEQVDFDRLRRQRELKLFIAATQVSTGTLKIFRNADLSV--EA 175 D L+D L +DFD L ++ +L + A V TG F + + E Sbjct: 112 AEGATSFYDTAELKDTLESLIDFDVLNDGKK-RLSVGAVNVRTGNFVYFDTEKVRIGPEH 170 Query: 176 LLASACLPSLHRPIEIEGEAYWDGGLTANPPIFPLLHACAARDVMVVLLHP-SRRAGTPT 234 ++AS LP + IEGE YWDGG+ +N P+ LL R +V + S R P Sbjct: 171 IMASGALPPAFPSVRIEGEYYWDGGIVSNTPLQYLLDQEEDRSSLVFQVDLFSARGVLPR 230 Query: 235 STHDIGQRLSEISFSSAFFTELSALALAKREAENSTLAFGSLERRLRQLNMHMIDANELM 294 S D+ R +I +SS +T F +R+ L M ++DA + + Sbjct: 231 SMPDVLSRHKDIMYSS--------------RTRQNTDNF----KRIHGLKMRLLDALKRV 272 Query: 295 --EQLTNLSKLNTQASFIGSLFQQGRERAAEWLEQNFAQVGHASTFDL 340 EQLT + + I G + Q+ GHA ++ Sbjct: 273 PKEQLT-----PAEEALIADYSDAGLVNIVHLIYQHKGYEGHAKDYEF 315 >mlr2398 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Mlo Mesorhizobium loti Length = 390 Score = 87.8 bits (216), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 79/272 (29%), Positives = 126/272 (46%), Gaps = 33/272 (12%) Query: 4 EKDIMSNKIISLALQGGGSHGAFTWGVLDRLLEDGRLGFEGISGASAGAMNAVVLAQGYV 63 EK + + I+L LQGGG+ GA+ GV + L E + + ++G S GA+N+ ++A Sbjct: 12 EKRPLPFECIALVLQGGGALGAYQAGVYEALAE-ADIHPDWVAGVSIGAINSAIIAGNEP 70 Query: 64 QDGREGARAALERFWTALSTGAPLDYINAEGAPVIANPTPMPGM--------QALLA-MT 114 + RA FW +S LD+ A +P +A +P + AL+A Sbjct: 71 TERVPKLRA----FWREISANPLLDW--AAASPALAPTGTLPRLLFNQFSAACALVAGAP 124 Query: 115 RFFSPTQLNP-------------LDINPLRDILLEQVDFDRLRRQRELKLFIAATQVSTG 161 FFS Q P + L+ L VDFDR+ R ++ + A V +G Sbjct: 125 GFFSLRQPVPWLQADGSLEGTSFYETKHLKSTLERLVDFDRINAGR-MRFSVGAVNVRSG 183 Query: 162 TLKIFRNADLSV--EALLASACLPSLHRPIEIEGEAYWDGGLTANPPIFPLLHACAARDV 219 F N ++ E ++AS LP +EI+GE YWDGGL +N P+ ++ A +D Sbjct: 184 NFVYFDNDQHTIRPEHVMASGSLPPGFPAVEIDGEFYWDGGLISNTPLQWVVEHGARQDT 243 Query: 220 MVVLLH-PSRRAGTPTSTHDIGQRLSEISFSS 250 + + S R P + ++ R EI ++S Sbjct: 244 LAFQVDLWSARGEFPRNLSEVATRQKEIQYAS 275 >slr0060 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Syn Synechocystis Length = 369 Score = 85.1 bits (209), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 82/278 (29%), Positives = 125/278 (44%), Gaps = 37/278 (13%) Query: 13 ISLALQGGGSHGAFTWGVLDRLLED---GRLGFEGISGASAGAMNAVVLAQGYVQDGREG 69 +++A QGGGS AFT GV+ L E+ +SG S GA+ A+++ ++ G Sbjct: 5 VAIACQGGGSQTAFTAGVMKALFENKMQDHFDIVSLSGTSGGAICALLIWYA-LKKGENP 63 Query: 70 ARAALERFWTALSTGAPL-----DYI------NAEGAPVIANPTPMPGMQALLAMTRFFS 118 L FW S D++ ++G + TP + LA T S Sbjct: 64 VWKRLLDFWLDNSAQTYQERFFNDFVIRSLELTSKGIVPQYSVTPY----SPLAQTWLAS 119 Query: 119 PTQ-LNPLDINPLRDILLEQVDFDRL----RRQRELKLFIAATQVSTGTLKIF--RNADL 171 TQ L IN L ++L VDF L ++ L I A + TG L F R + Sbjct: 120 ATQGLRSRFIN-LEELLQVHVDFSELATWGKQLEPPVLLIGACNILTGKLDKFNSRQEAI 178 Query: 172 SVEALLASACLPSLHRPIEIEGE----AYWDGGLTANPPIFPLLH------ACAARDVMV 221 +E LLASAC+P++ + IE E AYWDG + NPPI L +++ V Sbjct: 179 RIEHLLASACVPNIFPTVVIEEEGEKKAYWDGLFSDNPPIRSLYRQDFVGIENIPQEIWV 238 Query: 222 VLLHPSRRAGTPTSTHDIGQRLSEISFSSAFFTELSAL 259 + ++P++ PT DI R +E+ + + F L + Sbjct: 239 IKINPTQTDKIPTDADDIADRRNELEGNVSLFQSLDQI 276 >RSp1060 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Rso Ralstonia solanacearum Length = 377 Score = 82.8 bits (203), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 79/263 (30%), Positives = 118/263 (44%), Gaps = 39/263 (14%) Query: 17 LQGGGSHGAFTWGVLDRLLEDGRLGFEGISGASAGAMNAVVLAQGYVQDGREGARAALER 76 LQGGG+ GA+ GV + L G + I+G S GA+N ++A + E A L Sbjct: 2 LQGGGALGAYQAGVFEGLDAAG-IAPNWIAGISIGALNTAIIA----GNAPEQRLARLRE 56 Query: 77 FWTALST---GAPLDYINAEGAPVIANPTPMPGMQALLAMT----------RFFSP---- 119 FW + PL I E A N M + L AM FF+P Sbjct: 57 FWQTICQPGFSPPLPDI-LENAWFDGN---MHMRKWLTAMQIGETFIEGQRGFFAPRWPA 112 Query: 120 ----TQLNPL-----DINPLRDILLEQVDFDRLRRQRELKLFIAATQVSTGTLKIFRNAD 170 ++++PL D PL+ L DFDR+ +++ + A V TG L+ F N + Sbjct: 113 PLPASEVDPLEASYYDTTPLKATLERLCDFDRI-NDGGIRVSVGAVNVRTGNLECFDNTE 171 Query: 171 --LSVEALLASACLPSLHRPIEIEGEAYWDGGLTANPPIFPLLHACAARDVMVVLLHPSR 228 L E +AS LP P+ I+GE YWDGG+ +N P+ +L + RD +V + Sbjct: 172 RRLRAEHFMASGALPPGFPPVLIDGEYYWDGGVVSNTPLSYVLESTPRRDTLVFQVDLWS 231 Query: 229 RAG-TPTSTHDIGQRLSEISFSS 250 G P + + R ++ +SS Sbjct: 232 AVGPVPDTMIGVASRRKDLQYSS 254 >PA3241 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily Pae Pseudomonas aeruginosa Length = 389 Score = 67.0 bits (162), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 70/235 (29%), Positives = 106/235 (45%), Gaps = 34/235 (14%) Query: 12 IISLALQGGGSHGAFTWGVL----DRLLEDGRLGFEGISGASAGAMNAVVLAQGYVQDGR 67 + L L GGG+ A+ GVL D L + F I G SAGA+NAV LA G +Q Sbjct: 11 LTGLILSGGGARAAYQVGVLAAIADLLPDSAGNPFPVIVGTSAGAINAVGLACGALQ--- 67 Query: 68 EGARAALERFWTALSTGAPLDYINAEGAPVIANPTPMPGMQALLAMTRFFSPTQLNPLDI 127 R A++R TA+ G +++ P + +LL + R P L LD Sbjct: 68 --FRQAIQRL-TAVWQGFRTEHVYRSDWPGVTRQASRFLGHSLLGLGRRV-PVAL--LDN 121 Query: 128 NPLRDILLEQVDFDRLR---RQRELK-LFIAATQVSTGTLKIFRNADLSVEA-------- 175 PL ++L ++DF + RQR+L+ + + A +G F +++ Sbjct: 122 RPLHELLARELDFSGIHAAVRQRQLRAVAVTAFGYESGQAVTFYQGRATIDPWVRHRRLG 181 Query: 176 ---------LLASACLPSLHRPIEIEGEAYWDGGLTANPPIFPLLHACAARDVMV 221 LLASA +P L P+ I E + DG + + PI P LH A R +++ Sbjct: 182 IPTRLELRHLLASAAIPLLFPPVRINREYFGDGAVRSQAPISPALHLGATRVLVI 236