BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0073.p (159 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1977 [R] COG1286 Uncharacterized membrane protein, required f... 114 7e-26 PM0702 [R] COG1286 Uncharacterized membrane protein, required fo... 84 1e-16 HI1206 [R] COG1286 Uncharacterized membrane protein, required fo... 81 1e-15 YPO2771 [R] COG1286 Uncharacterized membrane protein, required f... 77 1e-14 VC1003 [R] COG1286 Uncharacterized membrane protein, required fo... 75 4e-14 PA3109 [R] COG1286 Uncharacterized membrane protein, required fo... 74 2e-13 NMB0691 [R] COG1286 Uncharacterized membrane protein, required f... 72 7e-13 cvpA [R] COG1286 Uncharacterized membrane protein, required for ... 68 7e-12 STM2363 [R] COG1286 Uncharacterized membrane protein, required f... 66 3e-11 ZcvpA [R] COG1286 Uncharacterized membrane protein, required for... 65 6e-11 >RSc1977 [R] COG1286 Uncharacterized membrane protein, required for colicin V production Rso Ralstonia solanacearum Length = 165 Score = 114 bits (286), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 61/156 (39%), Positives = 100/156 (64%), Gaps = 1/156 (0%) Query: 1 VLLILGCSVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPG-ELTRLIVA 59 VL I+ S ++G RGL+RE+L+LAGW+ A VA T+ A +PE +PG + R ++ Sbjct: 10 VLFIVVASALVGLFRGLIREILALAGWLFAAWVAYTFSGVAAGWMPESLPGGPVARTVLG 69 Query: 60 FIALFIGTRLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLVVVAALLCGTTAI 119 F+ LF+ T + +LV LS ++++ GL DR LG FG+ARG ++++V + G T++ Sbjct: 70 FVLLFVVTVIGTSLVGALLSAVLESAGLKPADRGLGMVFGLARGGVIILVLMTVAGFTSV 129 Query: 120 PQQAFWKEARFSPWVEQAAEAVLPYLPGKLAEHVSF 155 P+Q FW++A P+ E+AA A P LP +A+++ + Sbjct: 130 PEQPFWRDALTRPYAEEAARAAKPLLPPDVAKYIHY 165 >PM0702 [R] COG1286 Uncharacterized membrane protein, required for colicin V production Pmu Pasteurella multocida Length = 163 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 55/146 (37%), Positives = 75/146 (51%), Gaps = 9/146 (6%) Query: 14 LRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAFIALFIGTRLLMAL 73 LRG +REV+S+A WVVA VAN + LA L ++ L R A LF+ T ++ + Sbjct: 19 LRGFIREVMSVASWVVAFFVANHFYPYLANYLTQIESLYL-RNGTAIAILFVATLIVGGI 77 Query: 74 VARTLSELVKATGLTLLDRTLGSFFGVARGVLLVVVAALLCGT-TAIPQQAFWKEARFSP 132 V L ELV TGLT DR LG+ FG+ RGVL+V T T Q +WKE++ P Sbjct: 78 VNHILGELVDKTGLTGTDRVLGACFGLIRGVLIVAALLFFMDTFTNFSQTVWWKESKLIP 137 Query: 133 -------WVEQAAEAVLPYLPGKLAE 151 W Q +A ++ L + Sbjct: 138 HFGFIVEWFFQQLQATSSFINSTLNK 163 >HI1206 [R] COG1286 Uncharacterized membrane protein, required for colicin V production Hin Haemophilus influenzae Length = 163 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 54/152 (35%), Positives = 80/152 (52%), Gaps = 6/152 (3%) Query: 8 SVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAFIALFIGT 67 S+++ LRG VREVLSL W+VA +VA+ + LA L + + R A LF+ T Sbjct: 13 SILVSLLRGFVREVLSLGSWIVAFIVASQFYPYLAAYLTQ-IESMYIRNGTAIAILFVLT 71 Query: 68 RLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLVVVAALLCGT-TAIPQQAFWK 126 ++ A+V +S+LV TGL+ DR LG+ FG+ RG L+V T T Q +WK Sbjct: 72 LIVGAIVNYVISQLVDKTGLSGTDRVLGAAFGLVRGALIVAALLFFMDTFTNFEQTDWWK 131 Query: 127 EARFSPWVEQAAEAVLPYLPGKLAEHVSFATP 158 E++ P ++ + +L SF TP Sbjct: 132 ESQLIP----HFGFIIEWFFQQLQASSSFLTP 159 >YPO2771 [R] COG1286 Uncharacterized membrane protein, required for colicin V production Ype Yersinia pestis Length = 169 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 53/154 (34%), Positives = 75/154 (48%), Gaps = 9/154 (5%) Query: 4 ILGCSVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAFIAL 63 I+G S ++ +RG VRE LSL W A VA+ + LA E+ R +A L Sbjct: 11 IIGFSALVSLIRGFVREALSLVTWGCAFFVASHFYTYLAVYFTRF-EDEIVRNGIAIGIL 69 Query: 64 FIGTRLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLVVVAALLCGT-TAIPQQ 122 FI T ++ A+V +S LV+ TGL+ DR LG FG RGVL+V T T Q Sbjct: 70 FIATLIVGAIVNYVISSLVERTGLSGTDRVLGVCFGALRGVLIVSAMLFFLDTFTGFSQS 129 Query: 123 AFWKEARFSP-------WVEQAAEAVLPYLPGKL 149 WK+++ P W ++ +LP +L Sbjct: 130 VDWKQSQLIPQFSYIIRWFFDYLQSTSSFLPNQL 163 >VC1003 [R] COG1286 Uncharacterized membrane protein, required for colicin V production Vch Vibrio cholerae Length = 163 Score = 75.5 bits (184), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 46/133 (34%), Positives = 70/133 (52%), Gaps = 2/133 (1%) Query: 1 VLLILGCSVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAF 60 +L ++G S +I +RG +E LSL W A +A+ Y LA + ++ R A Sbjct: 8 ILSVIGLSALISLVRGFAKEALSLVIWFGAFYIASEYYAKLAVYFTN-IKDDMFRNGAAI 66 Query: 61 IALFIGTRLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLVVVAALLCGT-TAI 119 ALF+ T ++ A+V +++LV+ TGL+ DR LG FG RGVL+V TA Sbjct: 67 AALFVATLIVGAIVNYVIAQLVEKTGLSGTDRILGVVFGALRGVLIVAAGLFFMDAFTAF 126 Query: 120 PQQAFWKEARFSP 132 P +WK ++ P Sbjct: 127 PNTEWWKSSQLVP 139 >PA3109 [R] COG1286 Uncharacterized membrane protein, required for colicin V production Pae Pseudomonas aeruginosa Length = 180 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 56/129 (43%), Positives = 73/129 (56%) Query: 4 ILGCSVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAFIAL 63 I+ S +I RG V+E LSL W+VA VA +G ALA L E + R+I A L Sbjct: 13 IIVVSSLISLSRGFVKEALSLLTWIVAGAVAWMFGGALAQHLGEYIQTPSARIIAACALL 72 Query: 64 FIGTRLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLVVVAALLCGTTAIPQQA 123 FI T LL ALV + EL++ TGL+ DR LG FG ARGVLLVV+ L + Q Sbjct: 73 FIATLLLGALVNYLIGELIRVTGLSGTDRFLGMVFGGARGVLLVVLLVGLLSLAPVQQDP 132 Query: 124 FWKEARFSP 132 +W+++ P Sbjct: 133 WWQQSVLMP 141 >NMB0691 [R] COG1286 Uncharacterized membrane protein, required for colicin V production Nme Neisseria meningitidis MC58 Length = 165 Score = 71.6 bits (174), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 41/144 (28%), Positives = 74/144 (51%) Query: 4 ILGCSVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAFIAL 63 ++ +++ +RG++ E S+A WVV+ A + + A + L L ++FI+L Sbjct: 14 VIAACIVLSAMRGVIAEAGSMAAWVVSFFFAKLFAASFADLAFASFQPRLFALALSFISL 73 Query: 64 FIGTRLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLVVVAALLCGTTAIPQQA 123 F+ L+ ++ L+ V A GL +R LG FG +GVL+V + +L T +P Sbjct: 74 FVIACLIQKMLRSLLTSAVSAVGLGFANRILGGVFGALKGVLIVTLLVMLASKTDLPDTE 133 Query: 124 FWKEARFSPWVEQAAEAVLPYLPG 147 W+++ P+ +EAVL + G Sbjct: 134 EWRQSYTLPFFVSLSEAVLNHSGG 157 >cvpA [R] COG1286 Uncharacterized membrane protein, required for colicin V production Eco Escherichia coli K12 Length = 162 Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 47/149 (31%), Positives = 71/149 (47%), Gaps = 2/149 (1%) Query: 1 VLLILGCSVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAF 60 ++ ++ S ++ +RG VRE LSL W A VA+ Y L+ EL R +A Sbjct: 8 IIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHYYTYLSVWFTGF-EDELVRNGIAI 66 Query: 61 IALFIGTRLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLV-VVAALLCGTTAI 119 LFI T ++ A+V + +LV+ TGL+ DR LG FG RGVL+V + L T + Sbjct: 67 AVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGVCFGALRGVLIVAAILFFLDSFTGV 126 Query: 120 PQQAFWKEARFSPWVEQAAEAVLPYLPGK 148 + W +++ P YL Sbjct: 127 SKSEDWSKSQLIPQFSFIIRCFFDYLQSS 155 >STM2363 [R] COG1286 Uncharacterized membrane protein, required for colicin V production Sty Salmonella typhimurium LT2 Length = 162 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 47/154 (30%), Positives = 73/154 (47%), Gaps = 9/154 (5%) Query: 1 VLLILGCSVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAF 60 ++ ++ S ++ +RG VRE LSL W A VA+ Y L+ EL R +A Sbjct: 8 IIAVIAFSCLVSLIRGFVREALSLVTWGCAFFVASHYYTYLSVWFTGF-EDELVRNGIAI 66 Query: 61 IALFIGTRLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLVVVAALLCGT-TAI 119 LFI T ++ A+V + +LV+ TGL+ DR LG FG RG L+V T T + Sbjct: 67 AVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGICFGALRGALIVAAILFFLDTFTGL 126 Query: 120 PQQAFWKEARFSP-------WVEQAAEAVLPYLP 146 + W +++ P W ++ +LP Sbjct: 127 SKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP 160 >ZcvpA [R] COG1286 Uncharacterized membrane protein, required for colicin V production EcZ Escherichia coli O157:H7 EDL933 Length = 162 Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 48/154 (31%), Positives = 74/154 (48%), Gaps = 9/154 (5%) Query: 1 VLLILGCSVIIGTLRGLVREVLSLAGWVVALVVANTYGEALATMLPEMVPGELTRLIVAF 60 ++ ++ S ++ +RG VRE LSL W A VA+ Y L+ EL R +A Sbjct: 8 IIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHYYTYLSVWFTGF-EDELVRNGIAI 66 Query: 61 IALFIGTRLLMALVARTLSELVKATGLTLLDRTLGSFFGVARGVLLV-VVAALLCGTTAI 119 LFI T ++ A+V + LV+ TGL+ DR LG FG RGVL+V + L T + Sbjct: 67 AVLFIATLIVGAIVNFVIGLLVEKTGLSGTDRVLGVCFGALRGVLIVAAILFFLDSFTGV 126 Query: 120 PQQAFWKEARFSP-------WVEQAAEAVLPYLP 146 + W +++ P W ++ +LP Sbjct: 127 SKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP 160