BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0037.p (301 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2115 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 152 6e-37 SMa0498 [K] COG0583 Transcriptional regulator Sme Sinorhizobium ... 102 8e-22 YPO1934 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 101 2e-21 BS_yofA [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis 94 3e-19 BH2712 [K] COG0583 Transcriptional regulator Bha Bacillus halodu... 86 8e-17 PA4203 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 84 3e-16 mll2048 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 83 9e-16 yneJ [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 82 1e-15 BS_gltR [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis 81 2e-15 ZyneJ [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 81 3e-15 >PA2115 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 317 Score = 152 bits (385), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 89/250 (35%), Positives = 147/250 (58%), Gaps = 11/250 (4%) Query: 1 MNLRFVEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVA 60 MNL+F+E F W A LKS AEKL TQ+++SSRIA LE+ELGV L R + LT Sbjct: 1 MNLKFLETFVWVARLKSFRLTAEKLFSTQASISSRIAVLEDELGVKLFVRDSRGVTLTPE 60 Query: 61 GQRFQRLAVKLLDMQRQIRQELGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYPDFA 120 G + A +++D ++Q L ++ +RIG++++V+H+WL + + +P Sbjct: 61 GDKVLAYAERMMDTMHALKQSLDTGASTQGRIRIGAMDTVIHTWLSPLVARVTETFPAVE 120 Query: 121 LELTVETSPVLTEQIRRGAQDLVF-TSTVGSDTAVRSRLMT-PMEMVF----VGHRERFG 174 +EL +T+ L+EQ+++G DL+F T ++ ++ + L + P+ + + HR+ Sbjct: 121 IELMADTARNLSEQLQKGYLDLIFQTDSLRHESVLNLELGSYPLRWIVSTGSIYHRDY-- 178 Query: 175 TRSHTLEELAAHDLITFQRGSQPHQGLLQLCQEWGVANPRIHAISSISAMVQLVEGGFGV 234 +L +LA ++TF + S+PHQ +L L GVA PR++ ++S++AM +L+ GFGV Sbjct: 179 ---ASLADLARERVVTFSKHSRPHQDVLGLLHANGVAAPRLNCVNSVAAMTRLLRDGFGV 235 Query: 235 ATLPRASVRQ 244 LP A V Q Sbjct: 236 GALPPALVSQ 245 >SMa0498 [K] COG0583 Transcriptional regulator Sme Sinorhizobium meliloti Length = 299 Score = 102 bits (255), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 75/264 (28%), Positives = 126/264 (47%), Gaps = 3/264 (1%) Query: 1 MNLRF--VEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLT 58 M L F +E+F+W + L+S AA KL+++Q T+S RI LEE LGV L R+ +Q LT Sbjct: 1 MTLSFSALESFYWVSQLRSFNAAANKLNVSQPTVSYRIRELEERLGVSLFVRQRRQLVLT 60 Query: 59 VAGQRFQRLAVKLLDMQRQIRQELGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYPD 118 G+ + A ++ + R I + + LR+G I+S LP+ L E+ R+ Sbjct: 61 SEGEALKHYAESMIAIARDIESNIKTRNTRLPTLRVGVIDSFAAVCLPSLLDELDIRFAG 120 Query: 119 FALELTVETSPVLTEQIRRGAQDLVFTSTVGSDTAVRSRLMTPMEMVFVG-HRERFGTRS 177 + TV+TS L +Q+ G D+ ST S V L+ + ++ H+ Sbjct: 121 ARIAATVDTSHKLADQLSEGLLDIAVLSTPPSHDNVALELLGRQSVDWIASHKLGLPQTI 180 Query: 178 HTLEELAAHDLITFQRGSQPHQGLLQLCQEWGVANPRIHAISSISAMVQLVEGGFGVATL 237 + EEL + S H A R++ +S+ ++ LVE G G++ L Sbjct: 181 VSDEELLRQRIFATPAPSNLHSLTTGFLAATAGAGLRLNVCNSLGTILNLVESGTGISIL 240 Query: 238 PRASVRQLTRRLPLRILRCQAQLP 261 P +++ R +++L+ + LP Sbjct: 241 PSRLLQEQIRHGTIQVLKTRTTLP 264 >YPO1934 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 320 Score = 101 bits (251), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 77/275 (28%), Positives = 119/275 (43%), Gaps = 5/275 (1%) Query: 1 MNLRFVEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVA 60 M L+ +EAF+WAA + + AAE+LHI+ S++S RI LE LG L DR + LT Sbjct: 1 MTLKQLEAFYWAARCSNFSIAAERLHISISSLSKRIVELEASLGCTLFDRSGYRAVLTET 60 Query: 61 GQRFQRLAVKLLDMQRQIRQELGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYPDFA 120 GQ A LL+ +IR LG G E +WLP+++ R YP Sbjct: 61 GQNLLPRAFALLESAAEIRNTLGASEGLSGICNFGVGELSALTWLPSFIASARLLYPKLL 120 Query: 121 LELTVETSPVLTEQIRRGAQDLVFTSTVGSDTAVRSRLMTPMEMVFVGH---RERFGTRS 177 L V+ L ++ +G D + S + S + + V++ GT Sbjct: 121 LAPHVDVGAALEGRVNKGEMDFAIIAGRSSRQNILSLPIAQAQFVWMASPTLANTVGTAD 180 Query: 178 HTLEELAAHDLITFQRGSQPHQGLLQLCQEWGVANPRIHAISSISAMVQLVEGGFGVATL 237 L + A LIT G+ + + +G+A+ +S A+V ++ G+ L Sbjct: 181 SALRQ--ALPLITLPPGAGSSRIIDAWLMAYGIASVARINCNSWGAIVGMLIASVGIGIL 238 Query: 238 PRASVRQLTRRLPLRILRCQAQLPALQIHASYRED 272 P + +L+ L L C L AL +R D Sbjct: 239 PTSWAEKLSLHNQLEYLPCSEPLAALNYSFQWRRD 273 >BS_yofA [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis Length = 285 Score = 94.4 bits (233), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 72/269 (26%), Positives = 128/269 (47%), Gaps = 10/269 (3%) Query: 6 VEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVAGQRFQ 65 ++ F A SIT+AA+ L+ QS +++R+ +LEE+L + L R + +LT AG+ Sbjct: 6 LKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNIRLFHRTNRGMKLTAAGENLL 65 Query: 66 RLAVKLLDMQRQIRQE--LGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYPDFALEL 123 + A ++L + Q + + GP LRIGS+E++ + LP R+P+ L + Sbjct: 66 QYADQVLSLLDQAEKSTRMSRQPKGP--LRIGSLETMAVTHLPEHAASFLRRFPEVDLSV 123 Query: 124 TVETSPVLTEQIRRGAQDLVFTSTVGSDTAVRSRLMTPMEMVFVGHRERFGTRSHTLEEL 183 + L +Q+ D F AVR ++ E+V + RE T E++ Sbjct: 124 NTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVSHDELVLISSREG------TAEDM 177 Query: 184 AAHDLITFQRGSQPHQGLLQLCQEWGVANPRIHAISSISAMVQLVEGGFGVATLPRASVR 243 ++ F G + +L +E G+ N +I ++ A+++ V G G A LP+++V Sbjct: 178 LQQPMLFFGAGCSHRDRVKRLLEEAGIHNQKIIEFGTLEAIIKGVSAGMGTALLPKSAVD 237 Query: 244 QLTRRLPLRILRCQAQLPALQIHASYRED 272 R + I + L+I YR+D Sbjct: 238 GSEHRTNVWIHQLPPSYQDLEIVFIYRKD 266 >BH2712 [K] COG0583 Transcriptional regulator Bha Bacillus halodurans Length = 296 Score = 86.3 bits (212), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 79/267 (29%), Positives = 127/267 (47%), Gaps = 22/267 (8%) Query: 1 MNLRFVEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVA 60 MNL F+ A+ KS ++AA KL+ITQ ++S I LEE L V L R K LT Sbjct: 1 MNLELYRVFYVTATEKSFSKAAAKLYITQPSVSHAIKQLEEMLEVQLFTRHAKGVELTKE 60 Query: 61 GQRFQ---RLAVKLLDMQRQIRQELGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYP 117 G+ + A+ ++ Q+ QEL G + IG +S ++ +Q + RYP Sbjct: 61 GEAIYPSIQQALGSINQAEQLLQELKQLEGG--RVTIGGSDSTFKYFVLPSIQRFQARYP 118 Query: 118 DFALELTVETSPVLTEQIRRGAQDLVFTSTVGSDTAVRSR------LMTPMEMVFVGHRE 171 + + L ++P + E++ G+ D F VR R +T + VG + Sbjct: 119 NIHIRLQHGSTPQIIEKLDNGSIDFGFV-----HLPVRERHVEIQPFLTISSLFVVGEQN 173 Query: 172 R-FGTRSHTLEELAAHDLITFQRGSQPHQGLLQLCQEWGV-ANPRIHAISSISAMVQLVE 229 R R LEE+ + LITF S Q L +L + G+ P I + S+ +++ V+ Sbjct: 174 RELAERPLPLEEVLDYPLITFSESSSSTQFLQRLFERQGLHVQPDIE-VGSVELLIECVK 232 Query: 230 GGFGVATLPRASV-RQLTRR--LPLRI 253 G GVA + + V R+L + +PL++ Sbjct: 233 LGMGVAFVTKDFVLRELEKGELMPLQM 259 >PA4203 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 284 Score = 84.3 bits (207), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 85/262 (32%), Positives = 119/262 (45%), Gaps = 18/262 (6%) Query: 1 MNLRFVEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVA 60 M+L +E F A S+TRAA++L QS +++RI LEE+LGV L R K+ LT Sbjct: 1 MDLSSLEIFRAVAHEASVTRAAQRLQRAQSNVTTRIRQLEEDLGVELFLRDGKRMSLTER 60 Query: 61 GQRFQRLAVKLLDMQRQIRQELGGHSAGPLA-LRIGSIESVVHSWLPAWLQEIRCRYPDF 119 G F A +LL + + RQ + H A P LR+GS+ES S LPA L P Sbjct: 61 GSEFLAYAEQLLALADEARQSM--HPAEPGGRLRLGSMESTAASRLPALLASYHKACPRV 118 Query: 120 ALELTVETSPVLTEQIRRGAQDLVFTST----VG--SDTAVRSRLMTPMEMVFVGHRERF 173 ALE++ TS L + +R D + G + +R + E++ + E Sbjct: 119 ALEVSTGTSHALFDGVRARRLDCALVAAGPGWAGELDGSGLRGEPLFREELLMILPAEH- 177 Query: 174 GTRSHTLEELAAHDLITFQRGSQPHQGLLQLCQEWGVANP-RIHAISSISAMVQLVEGGF 232 H + E+ L F RG Q E + P + + S A++ V G Sbjct: 178 -PPVHDVAEVRLRTLAGFARGCTYRQ-----LAEDSLGTPLTVQEVGSYHAILACVAAGA 231 Query: 233 GVATLPRASVRQLTRRLPLRIL 254 V LPR SV QL PLR L Sbjct: 232 CVGVLPR-SVLQLLGTPPLRSL 252 >mll2048 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 329 Score = 82.8 bits (203), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 71/252 (28%), Positives = 117/252 (46%), Gaps = 13/252 (5%) Query: 1 MNLRFVEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVA 60 M+ R ++ F A ++ITRAAE +H+ QS++S +I +LE ELG L R + LT A Sbjct: 1 MHPRLLKTFLAVARSRNITRAAEAVHLAQSSVSDQIQTLEAELGAALFTRSKSGLELTPA 60 Query: 61 GQRFQRLAVKLLDMQRQ---IRQELGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYP 117 G +A +LL + + G ++G AL IG++E++ + L WL + +P Sbjct: 61 GLALMPIAEELLRLDGEARAAVLAAAGRTSG--ALTIGALETIAAARLAPWLPGFQAGHP 118 Query: 118 DFALELTVETSPVLTEQIRRGAQDLVFT------STVGSDTAVRSRLMTPMEMVFVGHRE 171 D + + V S L + G D+ F + +D + R + +V V Sbjct: 119 DITVRMKVADSGTLRRLLEDGDIDVAFCFERRDGARGAADGRLARRTIGAEPLVLVAAPG 178 Query: 172 RFGTRSHTLEELAAHDLITFQRGSQPHQGLLQLCQEWGVANPRIHA-ISSISAMVQLVEG 230 + L +LAA + + G L E +A P+ A + SI A+ +LV Sbjct: 179 Q-ALAPGGLADLAALRFVATEPGCIYRHMLDTAFAEADMAPPKPAAEVGSIGAIARLVAT 237 Query: 231 GFGVATLPRASV 242 G G+ +PR +V Sbjct: 238 GAGLGLIPRLAV 249 >yneJ [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 293 Score = 82.4 bits (202), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 70/253 (27%), Positives = 112/253 (44%), Gaps = 19/253 (7%) Query: 1 MNLRFVEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVA 60 M+L +E F+ A SIT+AA K+H S +++R+ LE ELGV L R ++ RL+ A Sbjct: 1 MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELGVDLFIRENQRLRLSPA 60 Query: 61 GQRFQRLAVKLLDMQRQIRQELGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYPDFA 120 G F R + ++L + + R + G L +GS+ES +PA L E RYP Sbjct: 61 GHNFLRYSQQILALVDEARSVVAGDEPQGL-FSLGSLESTAAVRIPATLAEFNRRYPKIQ 119 Query: 121 LELTVETSPVLTEQIRRGAQDLVFTSTVGSDTAV------RSRLM--TPMEMVFVGHRER 172 L+ S + + + G + F + TA+ R LM TP V Sbjct: 120 FSLSTGPSGTMLDGVLEGKLNAAFIDGPINHTAIDGIPVYREELMIVTPQGYAPV----- 174 Query: 173 FGTRSHTLEELAAHDLITFQRGSQPHQGLLQLCQEWGVANPRIHAISSISAMVQLVEGGF 232 TR+ ++ ++ F+ + G A IH + S M+ V G Sbjct: 175 --TRA---SQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESYHGMLACVIAGA 229 Query: 233 GVATLPRASVRQL 245 G+A +PR+ + + Sbjct: 230 GIALIPRSMLESM 242 >BS_gltR [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis Length = 296 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 66/251 (26%), Positives = 114/251 (45%), Gaps = 20/251 (7%) Query: 1 MNLRFVEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVA 60 MN++ ++ F A SI++AA L+ QS ++++I LE +L L R + LT Sbjct: 1 MNIQLLQVFLTTAREGSISKAALTLNYAQSNVTNKIQQLENDLQTKLFYRHSRGITLTPP 60 Query: 61 GQRFQRLAVKLLDMQRQIRQELGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYPDFA 120 GQ + K+L + R +G SA LRIGS+E+ WLP L YP+ Sbjct: 61 GQILVSYSEKILHTIEEARAAMGESSAPSGPLRIGSMETTAAVWLPQLLAHYNNLYPNVD 120 Query: 121 LELTVETSPVLTEQ-----IRRGAQDLVFTSTVGSDTAVRSRLMTPMEMVFVGHRERFGT 175 L L T P TEQ + + + V+ +++ EMV V + Sbjct: 121 LNLV--TGP--TEQQIQAVLHYELNGAFISGPIEHPDLVQEKVLDE-EMVLV------TS 169 Query: 176 RSH----TLEELAAHDLITFQRGSQPHQGLLQLCQEWGVANPRIHAISSISAMVQLVEGG 231 SH +++++ ++ F++G L + QE G+ ++ + A++ V G Sbjct: 170 ASHPVISSIQDVQTQTMVVFRKGCSYRAKLNHILQEEGLLPIKLMEFGILEAIIGCVSAG 229 Query: 232 FGVATLPRASV 242 G++ LPR+ + Sbjct: 230 LGISLLPRSII 240 >ZyneJ [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 80.9 bits (198), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 66/248 (26%), Positives = 109/248 (43%), Gaps = 9/248 (3%) Query: 1 MNLRFVEAFHWAASLKSITRAAEKLHITQSTMSSRIASLEEELGVVLLDRREKQFRLTVA 60 M+L +E F+ A SIT+AA +H S +++R+ LE ELGV L R ++ RL+ A Sbjct: 1 MDLTQLEMFNAVAEAGSITQAAAIVHRVPSNLTTRLRQLETELGVDLFIRENQRLRLSPA 60 Query: 61 GQRFQRLAVKLLDMQRQIRQELGGHSAGPLALRIGSIESVVHSWLPAWLQEIRCRYPDFA 120 G F R + ++L + + R + G L +GS+ES +PA L E RYP Sbjct: 61 GHNFLRYSQQILALVDEARSVVAGDEPQGL-FXLGSLESTAAVRIPATLAEFNRRYPKIQ 119 Query: 121 LELTVETSPVLTEQIRRGAQDLVFTSTVGSDTAVRSRLMTPMEMVFV---GHRERFGTRS 177 L+ S + E + G + F + TA+ + E++ V GH Sbjct: 120 FSLSTGPSGTMLEGVLEGKLNAAFIDGPINHTAIDGIPVYREELMIVTPQGHAPVI---- 175 Query: 178 HTLEELAAHDLITFQRGSQPHQGLLQLCQEWGVANPRIHAISSISAMVQLVEGGFGVATL 237 ++ ++ F+ + G A IH + S M+ V G G+A + Sbjct: 176 -RASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESYHGMLACVVAGAGIALI 234 Query: 238 PRASVRQL 245 PR+ + + Sbjct: 235 PRSMLESM 242