BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0035.p (414 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1932 [GEPR] COG0477 Permeases of the major facilitator superf... 449 e-126 PA2114 [GEPR] COG0477 Permeases of the major facilitator superfa... 427 e-119 RSp0234 [GEPR] COG0477 Permeases of the major facilitator superf... 390 e-108 PM0835 [GEPR] COG0477 Permeases of the major facilitator superfa... 218 3e-56 RSp0797 [GEPR] COG0477 Permeases of the major facilitator superf... 191 3e-48 HI1104 [GEPR] COG0477 Permeases of the major facilitator superfa... 188 2e-47 SPy1340 [GEPR] COG0477 Permeases of the major facilitator superf... 148 2e-35 BS_yceI [GEPR] COG0477 Permeases of the major facilitator superf... 147 3e-35 yjhB [GEPR] COG0477 Permeases of the major facilitator superfami... 143 6e-34 PA1019 [GEPR] COG0477 Permeases of the major facilitator superfa... 140 5e-33 >YPO1932 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 409 Score = 449 bits (1156), Expect = e-126, Method: Compositional matrix adjust. Identities = 222/407 (54%), Positives = 294/407 (72%) Query: 2 WLQETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSA 61 W + +ER+T A F G+A+D D+M++TF+I TL+A W + +AG ++T LL SA Sbjct: 3 WFSDLNQTERKTFIAAFGGWALDALDFMVFTFVIATLMALWQIDAGQAGMLSTVTLLFSA 62 Query: 62 IGGWAAGVLADRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVG 121 IGGW AG+LADRYGRVR+LQ T+LWF+ T L GF +F +F RA+QG G GGEWAVG Sbjct: 63 IGGWGAGILADRYGRVRILQITILWFSLCTVLIGFAQNFEHVFILRALQGLGFGGEWAVG 122 Query: 122 SVLIAETISARHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETAWKVLFWIGVLPAL 181 SVL+ E + A HRGKA G VQS WA+GW +AL + +++VL E AW+ LFWIGVLPAL Sbjct: 123 SVLMGEIVRAEHRGKAVGTVQSGWAIGWGAAALLYTLMFSVLSEEWAWRALFWIGVLPAL 182 Query: 182 LTLYIRRAISEPAVYLATQARLRETGQRGNFLRIFHRDLLRTTLLASLLATGMQGAYYSV 241 L LYIR+ + EPA++L ++ + +R + IF LL+TT+LASLL TG+QG YY++ Sbjct: 183 LVLYIRKNVPEPALFLKSRHEQQAKDRRVSSFAIFSPALLKTTVLASLLCTGVQGGYYAI 242 Query: 242 TTWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVL 301 TTWLPTFLK ER+LSV+GT YL+V+I GSF GY+ A+L+D +GRR ++F+ + + Sbjct: 243 TTWLPTFLKLERNLSVIGTGGYLMVIIFGSFVGYICGAYLTDKLGRRANLIIFSLLSCIT 302 Query: 302 VLSYTQMIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVG 361 + +YTQ+ +T+ ML LGF LGF SGIFSGMGA+L+ELFPS VR +GQGF Y+FGRAVG Sbjct: 303 IFAYTQLTLTNTQMLVLGFPLGFSASGIFSGMGAFLTELFPSAVRATGQGFTYSFGRAVG 362 Query: 362 AICPALVGYLSNSLPLGQTIGWIAAGCYGLVIVACLVLPETRGKELE 408 A+ P LVGYLS S L IG A Y +V+V L+LPET+ K+LE Sbjct: 363 ALFPGLVGYLSQSSSLAFAIGVFAGSAYCIVLVMSLLLPETKNKQLE 409 >PA2114 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 423 Score = 427 bits (1099), Expect = e-119, Method: Compositional matrix adjust. Identities = 222/408 (54%), Positives = 283/408 (69%), Gaps = 3/408 (0%) Query: 2 WLQETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSA 61 W + ERR + GY +DG D + +F+IPTL+A W + EAG+I T LL SA Sbjct: 17 WYRALDKQERRAFWSCKIGYGLDGMDTQMLSFVIPTLIALWGIGTGEAGFIHTMTLLASA 76 Query: 62 IGGWAAGVLADRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVG 121 GGW AG+L+DR GRV LQ TVLWFAFFTFL G ++ QL R + GFG GGEW G Sbjct: 77 AGGWIAGILSDRIGRVLTLQLTVLWFAFFTFLCGLAQNYEQLLVARTLMGFGFGGEWTAG 136 Query: 122 SVLIAETISARHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETAWKVLFWIGVLPAL 181 +VLI E I AR RGKA GLVQS WA+GW +A+ + ++++LPPE AW+ LF +G+LPAL Sbjct: 137 AVLIGEVIKARDRGKAVGLVQSGWAIGWGLTAILYSLMFSLLPPEEAWRALFMLGLLPAL 196 Query: 182 LTLYIRRAISEPAVYLATQARLRETG-QRGNFLRIFHRDLLRTTLLASLLATGMQGAYYS 240 L +RR + EP +Y +AR R G + +F IF +L TL ASLL TG G YY+ Sbjct: 197 FVLVVRRLVKEPEIY--REARQRNQGADKVSFYEIFAPGMLSITLRASLLTTGALGGYYA 254 Query: 241 VTTWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIV 300 +T WLPTFLKTER L+VLGTS YL ++I GS+ GY+ SA+L+D IGR++ F+LFA Sbjct: 255 ITAWLPTFLKTERGLTVLGTSGYLAMVILGSYVGYVVSAFLTDLIGRKKNFVLFAVGSFT 314 Query: 301 LVLSYTQMIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAV 360 +VL YTQ+ +++ ML LGF LGFF SGIFSGMG++L+ELFP+ +RGSGQGFCYN GRA+ Sbjct: 315 VVLLYTQLPVSNGAMLWLGFPLGFFASGIFSGMGSFLTELFPTRIRGSGQGFCYNAGRAI 374 Query: 361 GAICPALVGYLSNSLPLGQTIGWIAAGCYGLVIVACLVLPETRGKELE 408 A+ P L+G L L LG IG AA YG+VI+A L LPETRGK+LE Sbjct: 375 AALFPMLIGMLGQKLSLGLGIGAFAAVSYGVVILAALSLPETRGKQLE 422 >RSp0234 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 416 Score = 390 bits (1003), Expect = e-108, Method: Compositional matrix adjust. Identities = 211/412 (51%), Positives = 273/412 (66%), Gaps = 4/412 (0%) Query: 2 WLQETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSA 61 W +E + E+RT A F G+A+D D +++ +IPT++AAW + K EAG ++ L+ SA Sbjct: 4 WFKEISAGEKRTFWACFGGWALDALDVQMFSLVIPTIIAAWHIGKTEAGLVSGITLVASA 63 Query: 62 IGGWAAGVLADRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVG 121 +GGW AG + DR GRVR LQ TV WF+ TF S F +F Q +A+QGFG GGEWA G Sbjct: 64 LGGWIAGAMTDRLGRVRTLQITVAWFSLATFASAFAQNFEQFLALKAVQGFGFGGEWAAG 123 Query: 122 SVLIAETISARHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETAWKVLFWIGVLPAL 181 +VL+AE+I A HRGKA G VQS+WAVGW + L + Y+++ P+ AW+V+F GVLPAL Sbjct: 124 AVLMAESIRASHRGKAMGTVQSAWAVGWGAAVLLYALTYSLVEPDLAWRVMFAAGVLPAL 183 Query: 182 LTLYIRRAISEPAVYLATQARLRETG---QRGNFLRIFHRDLLRTTLLASLLATGMQGAY 238 L +YIRR + EPA +A G R L IF +LR TL+ +LL G G Y Sbjct: 184 LIIYIRRGVQEPAPA-GAKAEAGPDGMPVSRFPLLDIFRPRVLRMTLIGALLGVGAHGGY 242 Query: 239 YSVTTWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMG 298 Y++ TWLPT+LKTERHLSVLGT YL V+I +CG + SAWL D IGRR +LF+ Sbjct: 243 YALMTWLPTYLKTERHLSVLGTGGYLAVIIFAFWCGCVASAWLLDVIGRRGNILLFSCCC 302 Query: 299 IVLVLSYTQMIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGR 358 +V VL Y + ++D ML LGF LGFF +GI + MGA +EL+P VRG+G GFCYNFGR Sbjct: 303 VVTVLVYLLVPLSDGAMLVLGFPLGFFAAGIPASMGALFNELYPHGVRGTGVGFCYNFGR 362 Query: 359 AVGAICPALVGYLSNSLPLGQTIGWIAAGCYGLVIVACLVLPETRGKELEAV 410 V A P LVG +S S+ LG IG AA Y +V VA L+LPETRG++L AV Sbjct: 363 VVSAAFPVLVGKMSASMSLGTAIGIDAAIAYSIVAVAVLMLPETRGRDLAAV 414 >PM0835 [GEPR] COG0477 Permeases of the major facilitator superfamily Pmu Pasteurella multocida Length = 405 Score = 218 bits (554), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 134/400 (33%), Positives = 213/400 (53%), Gaps = 8/400 (2%) Query: 12 RTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSAIGGWAAGVLA 71 + L + GYA+DGFD +I F++ + A +++ A++G + T L+ + GG G L+ Sbjct: 11 KALLGSAVGYAMDGFDLLILGFMLSAISADLALTPAQSGSLVTWTLIGAVAGGIIFGALS 70 Query: 72 DRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVGSVLIAETISA 131 D+YGRVRVL WT++ FA FT L F + L R + G G+GGE+ +G L AE A Sbjct: 71 DKYGRVRVLTWTIVLFAVFTGLCAFAQGYWDLLIYRTIAGIGLGGEFGIGMALAAEAWPA 130 Query: 132 RHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETAWKVLFWIGVLPALLTLYIRRAIS 191 RHR KAS V A+GW L + +L P W+ +F +G+ PA + Y+R + Sbjct: 131 RHRAKASSYV----ALGWQVGVLGAALLTPLLLPHIGWRGMFLVGIFPAFVAWYLRAKLH 186 Query: 192 EPAVYLATQARL-RETGQRGNFLRIFHRDLLRTTLLASLLA-TGMQG-AYYSVTTWLPTF 248 EP +++ Q L R+ R R+ +D + A ++ T +Q YY + W+P F Sbjct: 187 EPEIFVKKQTALERQKTSRLEPFRLLIKDKATAKISAGIVVLTSVQNFGYYGIMIWMPNF 246 Query: 249 LKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVLVLSYTQM 308 L + S+ + + V I G G L+D IGR+ F+LF ++ + +Y+QM Sbjct: 247 LSKQLGFSLTKSGVWTAVTICGMMFGIWLFGQLADRIGRKPSFLLFQFGAVISIFTYSQM 306 Query: 309 IITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVGAICPALV 368 +ML G VLG F++G+ G GA +SE +P+ R + Q +N GRAVG P +V Sbjct: 307 -SDPTYMLFAGAVLGMFVNGMMGGYGALMSEAYPTQARATAQNVLFNLGRAVGGFGPIVV 365 Query: 369 GYLSNSLPLGQTIGWIAAGCYGLVIVACLVLPETRGKELE 408 G L ++ I ++A+ +I ++PE +GK+L+ Sbjct: 366 GALVSTYSFQLAIAFLASIYIIDMIATIFLIPELKGKQLD 405 >RSp0797 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 418 Score = 191 bits (484), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 140/405 (34%), Positives = 213/405 (52%), Gaps = 10/405 (2%) Query: 5 ETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSAIGG 64 T+ + L + GYA+DGFD +I F++P + AA +++ E+G + T L+ + GG Sbjct: 21 RTSGDAWKALAGSAIGYAMDGFDLLILGFMLPAISAALALTPGESGALVTWTLVGAVAGG 80 Query: 65 WAAGVLADRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVGSVL 124 G L+D YGRVRVL WT++ FA FT + F F L R + G G+GGE+ +G L Sbjct: 81 ILFGALSDAYGRVRVLTWTIVLFAVFTGMCAFAQGFTDLLIYRTIAGIGLGGEFGIGMAL 140 Query: 125 IAETISARHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETAWKVLFWIGVLPALLTL 184 AE A R + S V A+GW L + +L P W+ +F +GVLPA + Sbjct: 141 AAEAWPAHKRARVSSYV----ALGWQCGVLLAALLTPLLLPFIGWRGMFLLGVLPAAVAW 196 Query: 185 YIRRAISEPAVYLATQARLRETGQRGNF-LRIFHRDLLRTTLLASLLATGMQGAYYSVTT 243 +IR + EP +++ R G+ F L + LRT+L +L YY + Sbjct: 197 FIRNRLHEPELFVRHAHAPR--GKTSAFRLLVSDARTLRTSLGIVILCAVQNFGYYGIMI 254 Query: 244 WLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVLVL 303 WLPT+L S+ ++ + V I G G + L+D IGR+ F++F A + +VL Sbjct: 255 WLPTYLGKTLGFSLTKSALWTSVTILGMMLGIVAFGHLADRIGRKPTFLIFQAGAVAMVL 314 Query: 304 SYTQMIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVGAI 363 +Y ++ A + A G V+G F++G+ G GA +SE FP+ R + Q +N GRAVG Sbjct: 315 TYARLTDPLALLWA-GAVMGMFVNGMIGGYGALISEAFPTAARATAQNVLFNLGRAVGGF 373 Query: 364 CPALVGYLSNSLPLGQTIGWIAAGCYGLVIVACLVL-PETRGKEL 407 P +VG L+ + I + AG Y L ++A + L PE +G EL Sbjct: 374 GPVVVGSLAAAYSFRTAIALL-AGLYVLDMLATMALVPERKGAEL 417 >HI1104 [GEPR] COG0477 Permeases of the major facilitator superfamily Hin Haemophilus influenzae Length = 407 Score = 188 bits (478), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 127/402 (31%), Positives = 206/402 (51%), Gaps = 10/402 (2%) Query: 12 RTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSAIGGWAAGVLA 71 + L + GY +DGFD +I F++ + A +++ A+ G + T L+ + GG G L+ Sbjct: 11 KALIGSAVGYGMDGFDLLILGFMLSAISADLNLTPAQGGSLVTWTLIGAVFGGILFGALS 70 Query: 72 DRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVGSVLIAETISA 131 D+YGRVRVL WT+L FA FT L + L R + G G+GGE+ +G L AE A Sbjct: 71 DKYGRVRVLTWTILLFAVFTGLCAIAQGYWDLLIYRTIAGIGLGGEFGIGMALAAEAWPA 130 Query: 132 RHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETAWKVLFWIGVLPALLTLYIRRAIS 191 RHR KA+ V A+GW L + +L P W+ +F +G+ PA + ++R + Sbjct: 131 RHRAKAASYV----ALGWQVGVLGAALLTPLLLPHIGWRGMFLVGIFPAFVAWFLRSHLH 186 Query: 192 EPAVYLATQARLRETGQRGNFLRIFH---RDLLRTTL-LASLLATGMQG-AYYSVTTWLP 246 EP ++ Q L + LR F +D + + L ++ T +Q YY + WLP Sbjct: 187 EPEIFTQKQTALSTQSSFTDKLRSFQLLIKDKATSKISLGIVVLTSVQNFGYYGIMIWLP 246 Query: 247 TFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVLVLSYT 306 FL + S+ + + V + G G L+D IGR+ F+LF ++ ++ Y+ Sbjct: 247 NFLSKQLGFSLTKSGLWTAVTVCGMMAGIWIFGQLADRIGRKPSFLLFQLGAVISIVVYS 306 Query: 307 QMIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVGAICPA 366 Q+ D +LA G LG F++G+ G GA ++E +P++ R + Q +N GRAVG P Sbjct: 307 QLTDPDIMLLA-GAFLGMFVNGMLGGYGALMAEAYPTEARATAQNVLFNIGRAVGGFGPV 365 Query: 367 LVGYLSNSLPLGQTIGWIAAGCYGLVIVACLVLPETRGKELE 408 +VG + + I +A ++ ++PE +GK L+ Sbjct: 366 VVGSVVLAYSFQTAIALLAIIYVIDMLATIFLIPELKGKALD 407 >SPy1340 [GEPR] COG0477 Permeases of the major facilitator superfamily Spy Streptococcus pyogenes M1 GAS Length = 406 Score = 148 bits (374), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 111/364 (30%), Positives = 178/364 (48%), Gaps = 8/364 (2%) Query: 8 TSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSAIGGWAA 67 T+ +R L A D + M F + +++ +S + G+IAT L +GG Sbjct: 8 TTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGLSGTQGGWIATITNLGMLVGGLLF 67 Query: 68 GVLADRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVGSVLIAE 127 G+LADR+ + +V +WT+L F+ T L FT S L+ R + G G+GGE+ V ++A Sbjct: 68 GLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPYLYLMRFIAGIGVGGEYGVAIAIMAG 127 Query: 128 TISARHRGKASGLVQSSWAVGWAGSA-LAFWGVYAVLPPETAWKVLFWIGVLPALLTLYI 186 + G+ S L + +G SA LA W L P W+ LF G+LP LL +++ Sbjct: 128 IVPPEKMGRMSSLNGIAGQLGSISSALLAGW-----LAPSLGWRGLFLFGLLPILLVIWM 182 Query: 187 RRAISEPAVYLATQARLRETGQRGNFLRIFHRDLLRTTLLASLLATGMQGA-YYSVTTWL 245 AI + ++ E Q +F L LA ++ T +Q A Y+ + WL Sbjct: 183 TLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLTAQTLALMVMTTVQIAGYFGMMNWL 242 Query: 246 PTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVLVLSY 305 PT ++T +LSV +S +++ I G G L L D G R + LF + V + Sbjct: 243 PTIIQTSLNLSVKSSSLWMVATIVGMCLGMLYFGQLLDCFGPRLIYSLFLLASSICVYLF 302 Query: 306 TQMIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVGAICP 365 Q + A M+ G ++GFF++G+F+G GA ++ L+P +R + N GRA+G Sbjct: 303 -QFANSMASMVIGGAIVGFFVNGMFAGYGAMITRLYPHHIRSTANNVILNVGRALGGFSS 361 Query: 366 ALVG 369 +G Sbjct: 362 VAIG 365 >BS_yceI [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 400 Score = 147 bits (372), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 119/410 (29%), Positives = 203/410 (49%), Gaps = 17/410 (4%) Query: 4 QETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSAIG 63 ++ S+R+ L G+ D D I +F+I L W++S E +I + + A G Sbjct: 3 KQQPISQRKLLGVAGLGWLFDAMDVGILSFIIAALHVEWNLSPEEMKWIGSVNSIGMAAG 62 Query: 64 GWAAGVLADRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVGSV 123 + G+LADR GR +V T+L F+ + +S F TS R + G G+GGE V S Sbjct: 63 AFLFGLLADRIGRKKVFIITLLCFSIGSGISAFVTSLSAFLILRFVIGMGLGGELPVAST 122 Query: 124 LIAETISARHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETAWKVLFWIGVLPALLT 183 L++E + RG+ L++S WAVGW +AL + V P W+ + L A Sbjct: 123 LVSEAVVPEKRGRVIVLLESFWAVGWLAAALISYFVI----PSFGWQAALLLTALTAFYA 178 Query: 184 LYIRRAISEPAVYLATQARLRETGQRGNFLRIFHRDLLRTTLLASLLATGMQGAYYSVTT 243 LY+R ++ + Y + A+ R + N ++ R +R T++ S++ + +YY + Sbjct: 179 LYLRTSLPDSPKYESLSAKKRSMWE--NVKSVWARQYIRPTVMLSIVWFCVVFSYYGMFL 236 Query: 244 WLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAMGIVLVL 303 WLP+ + + S++ + Y+L++ GY ++AWL + GR+ +++ +G Sbjct: 237 WLPSVMLL-KGFSMIQSFEYVLLMTLAQLPGYFSAAWLIEKAGRKWILVVY-LIGTAGSA 294 Query: 304 SYTQMIITDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNFGRAVGAI 363 + + + +L G +L FF G + + AY E +P+ +R +G G FGR G Sbjct: 295 YFFGTADSLSLLLTAGVLLSFFNLGAWGVLYAYTPEQYPTAIRATGSGTTAAFGRIGGIF 354 Query: 364 CPALVGYLSN---SLPLGQTIGWIAAGCYGLVIVACLVL--PETRGKELE 408 P LVG L+ S + +I IA L+ VAC+++ ET+ ELE Sbjct: 355 GPLLVGTLAARHISFSVIFSIFCIAI----LLAVACILIMGKETKQTELE 400 >yjhB [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 425 Score = 143 bits (361), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 102/385 (26%), Positives = 189/385 (49%), Gaps = 19/385 (4%) Query: 2 WLQETTTSERRTLTATFTGYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSA 61 W ++ +R+ L + + GY DGFD+M+ +++ + A ++ +A I T A + Sbjct: 25 WYKQVNPPQRKALFSAWLGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAFIARP 84 Query: 62 IGGWAAGVLADRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVG 121 IGG G +AD+YGR ++ W + ++ T LSG T+ L R + G GM GE+A Sbjct: 85 IGGGFFGAMADKYGRKPMMMWAIFIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGEYACA 144 Query: 122 SVLIAETISARHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETA----WKVLFWIGV 177 S E+ + KAS + S ++VG + A + P+ A W+ F+IG+ Sbjct: 145 STYAVESWPKNLQSKASAFLVSGFSVGNI--------IAAQIIPQFAEVYGWRNSFFIGL 196 Query: 178 LPALLTLYIRRAISEPAVYLATQARLRETGQRGNFLRIFHRDLLRTTLLASLLATGMQGA 237 LP LL L+IR++ E ++ + + + T FL +F + L +++ L+ + GA Sbjct: 197 LPVLLVLWIRKSAPESQEWIEDKYKDKST-----FLSVFRKPHLSISMIVFLVCFCLFGA 251 Query: 238 YYSVTTWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLFAAM 297 + + LP++L + ++ + ST + + G+ G + ++ D IG ++ F++ Sbjct: 252 NWPINGLLPSYL-ADNGVNTVVISTLMTIAGLGTLTGTIFFGFVGDKIGVKKAFVVGLIT 310 Query: 298 GIVLVLSYTQMIITDAWMLALG-FVLGFFLSGIFSGMGAYLSELFPSDVRGSGQGFCYNF 356 + + + + ++ ++ L F L F GI + ++ + FP+ +RG G G YN Sbjct: 311 SFIFLCPLFFISVKNSSLIGLCLFGLMFTNLGIAGLVPKFIYDYFPTKLRGLGTGLIYNL 370 Query: 357 GRAVGAICPALVGYLSNSLPLGQTI 381 G G P L Y+S LG ++ Sbjct: 371 GATGGMAAPVLATYISGYYGLGVSL 395 >PA1019 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 451 Score = 140 bits (353), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 118/427 (27%), Positives = 196/427 (45%), Gaps = 32/427 (7%) Query: 10 ERRTLTATFT----GYAVDGFDYMIYTFLIPTLLAAWSMSKAEAGYIATGALLTSAIGGW 65 RRT+ F G DG D M + + +L A + +S EAG + + L A+GG Sbjct: 15 SRRTMLIAFVFCFLGLLADGVDLMFLAYSLNSLKAEFGLSNFEAGSLGSLTLAGMAVGGI 74 Query: 66 AAGVLADRYGRVRVLQWTVLWFAFFTFLSGFTTSFGQLFFTRAMQGFGMGGEWAVGSVLI 125 G DR+GRVRV+ WT++ F+ T L G T ++ Q R + G+G + ++L+ Sbjct: 75 YGGWCCDRFGRVRVVTWTIVLFSIGTALLGLTQNYWQFALIRFVASLGLGSLFVACNILM 134 Query: 126 AETISARHRGKASGLVQSSWAVGWAGSALAFWGVYAVLPPETAWKVLFWIGVLPALLTLY 185 +E + R+R +Q+ W VG+ + L + + PE W+ LF+ V PAL+ L Sbjct: 135 SECVGTRYRTTILAAMQAGWTVGYLVATL----LAGQIIPEFGWRTLFFTAVAPALVCLA 190 Query: 186 IRRAISEPAVYLATQA-RLR---------ETGQRGNFLRIFHRDLLRTT-LLASLLATGM 234 +R + E +LA QA R R E G G R+ R LL SL + + Sbjct: 191 LRPWVPESPSWLAAQAGRQRPGAAPQSHAEAGGAGPLGRMLGDPETRGMFLLWSLTSCFL 250 Query: 235 QGAYYSVTTWLPTFLKTERHLSVLGTSTYLLVLIGGSFCGYLTSAWLSDTIGRRRCFMLF 294 YY W+P++L++E ++ + Y++ G + + +D GRR F Sbjct: 251 LFGYYGTNNWMPSYLESELGMNFKSMTGYMVGTYSAMILGKVAAGVCADLFGRRLTF--- 307 Query: 295 AAMGIVLVLSYTQMII---TDAWMLALGFVLGFFLSGIFSGMGAYLSELFPSDVRGSGQG 351 A G + ++ +I+ + + +L + GF + Y++E F + VRGS G Sbjct: 308 -AAGAIGSAAFMPLIVFYHSPSNILWILITFGFIYGVPVGVLATYMTESFSTRVRGSAVG 366 Query: 352 FCYNFGRAVGAICPALVGYLSNSLPLG-----QTIGWIAAGCY-GLVIVACLVLPETRGK 405 YN GR A+ PA +G L+ + +G I ++ G L I L P + Sbjct: 367 TAYNLGRIGAAVAPAGIGLLATHVSIGAGFLVMGITYVLTGLIPALFIADRLYDPNRESR 426 Query: 406 ELEAVAK 412 + E+ ++ Sbjct: 427 DAESASR 433