BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0070.p (478 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_mmr [GEPR] COG0477 Permeases of the major facilitator superfa... 392 e-108 mll2542 [GEPR] COG0477 Permeases of the major facilitator superf... 242 1e-63 RSp1417 [GEPR] COG0477 Permeases of the major facilitator superf... 204 5e-52 Cgl1114 [GEPR] COG0477 Permeases of the major facilitator superf... 202 1e-51 XF1765 [GEPR] COG0477 Permeases of the major facilitator superfa... 194 4e-49 Cgl1213 [GEPR] COG0477 Permeases of the major facilitator superf... 187 4e-47 CAP0109 [GEPR] COG0477 Permeases of the major facilitator superf... 182 1e-45 MT2395 [GEPR] COG0477 Permeases of the major facilitator superfa... 181 4e-45 Rv2333c [GEPR] COG0477 Permeases of the major facilitator superf... 179 2e-44 PA1316 [GEPR] COG0477 Permeases of the major facilitator superfa... 177 4e-44 >BS_mmr [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 466 Score = 392 bits (1006), Expect = e-108, Method: Compositional matrix adjust. Identities = 212/444 (47%), Positives = 293/444 (65%), Gaps = 1/444 (0%) Query: 24 TPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLL 83 T G+ L+ LA+GF+MA LDVTVVNV ++++ +L LS + W+VDGY LTFA++LL Sbjct: 11 TSSTGISVLIVLALGFLMATLDVTVVNVAMADMKNTLSMSLSGVTWVVDGYILTFASLLL 70 Query: 84 VGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLL 143 GGALADRFG++ +Y+ GL +FV+AS LC A+ NG LIA RL+QG+GAA FMPSSLSLL Sbjct: 71 AGGALADRFGSKTIYILGLAVFVMASCLCAASINGQMLIAGRLIQGIGAALFMPSSLSLL 130 Query: 144 THVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMAR 203 Y D+R RARM G+W+A V A+A+GP +GGVL+ GW+S+FLINVP+G L+ A Sbjct: 131 AASYLDERARARMFGLWAALVSAASALGPFIGGVLVQLAGWQSIFLINVPIGAAALISAY 190 Query: 204 KLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALI 263 +++ +V G + +N+ HL G++ L LS+ LIQGP GW SP IL +LA + Sbjct: 191 RILSRVPGKSSRVNIIGHLLGMMALGFLSYALIQGPSAGWRSPVILVAFTAAVLAFVLFL 250 Query: 264 RHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQ 323 E+ P+LP +L+ +F+AA IGFL+NF ++G +F L+LFLQ+ GA + G++ Sbjct: 251 LREISAKTPILPASLYKNGRFSAAQFIGFLLNFALFGGMFMLSLFLQEAGGASSFMAGVE 310 Query: 324 LVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGF-SPATPYWLLALVCA 382 L+PMMAV GNL+ R++ + + + ++V + L SP PYW LA++ + Sbjct: 311 LLPMMAVFVIGNLLFARLANRFEAGQLMFVSMAVSCIIALLLFVLISPDFPYWQLAVLMS 370 Query: 383 SANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVTGWNL 442 NL +PAMTTV+MQ AG+ H N A AALNANRQIGALVGVA+ G I+H W Sbjct: 371 VMNLCTGITVPAMTTVIMQAAGQRHTNIAGAALNANRQIGALVGVAITGVIIHLSATWYA 430 Query: 443 RNPLAFGVMAAGYASALWLVWRFV 466 AF +M A Y+ A LVW F+ Sbjct: 431 GAGFAFLMMGAAYSLAALLVWLFL 454 >mll2542 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 505 Score = 242 bits (618), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 152/411 (36%), Positives = 234/411 (56%), Gaps = 10/411 (2%) Query: 30 LPLVA-LAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLLVGGAL 88 LPLVA + +G +A+LDV++VNV L I +L L W+VD YTL +A +L G + Sbjct: 6 LPLVAAVYLGTFVALLDVSIVNVALPTIQQALHTDFGGLQWVVDAYTLCLSAFMLSSGLI 65 Query: 89 ADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYE 148 DR+G +R +L G+ +FV SL+C APN P L+A R++QG+ + +P +LS+LT + Sbjct: 66 GDRYGRKRSWLAGVGIFVAGSLICAVAPNLPALLAGRVVQGIAGSLLIPGALSILTQAFP 125 Query: 149 DDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMARKLIPQ 208 D R RA ++G W+A ++ VGP++GG+L+ +GW+S+FLIN+P+GL +V+ I + Sbjct: 126 DPRERAGVIGGWAAFAAVSLVVGPVLGGILVQTVGWQSIFLINLPLGLFTIVLGAVSIEE 185 Query: 209 VAGHARA-LNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALIRHEL 267 + A L+L ++ L L+F LI GW PR + + V ++ A + E Sbjct: 186 TSHPEHAHLDLVGLALSILWLGALTFGLISAGESGWGDPRTIVAIIVGVVGLAVFLGFEA 245 Query: 268 RGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQLVPM 327 R P+LP LF +FA AN F + F Y +F+ ++FLQQ +G QTGL++ P Sbjct: 246 RTPRPMLPLGLFRDVRFAVANVASFALGFTSYSCVFFFSMFLQQVQGWSPTQTGLRMAPA 305 Query: 328 MAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAM-GFS---PATPYWLLALVCAS 383 V + GR+SA +G L ++ G V L+M G P+TPY LL ++ Sbjct: 306 FLVQIVVSPWIGRLSARYGHS----LLMTAGYVLIGLSMLGMCWAGPSTPYALLCVLFTI 361 Query: 384 ANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAIL 434 LG S AIP + M A + + +A +NA RQ G +G+AL+GA++ Sbjct: 362 NGLGNSLAIPTGSAAAMSYAPRERSGMVSAVINATRQSGLAIGIALLGALM 412 >RSp1417 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 467 Score = 204 bits (518), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 146/403 (36%), Positives = 217/403 (53%), Gaps = 10/403 (2%) Query: 32 LVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLLVGGALADR 91 L+ +I +MAMLD VV S I L A LS L W ++ Y L+ AA+L+ G AL DR Sbjct: 14 LILTSIATLMAMLDAMVVATATSAIRADLGASLSALQWTMNAYNLSLAALLMTGAALGDR 73 Query: 92 FGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYEDDR 151 FG RR+++TGL +FV AS+ C A + +LIAAR++QG G A P S++LL+ + +R Sbjct: 74 FGRRRVFVTGLCVFVAASIACALARSAEWLIAARVVQGAGGALVTPLSMALLSAAFPPER 133 Query: 152 VRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMARKLIPQVAG 211 R + LG++ GLA +GP++GGV+ L W+ +F +NVP+GL +V+A + IP G Sbjct: 134 -RGKALGLFGGITGLALILGPVLGGVIAGNLPWQWIFWLNVPIGLPLIVLAVRRIPDSKG 192 Query: 212 HARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAA----LIRHEL 267 A AL++ L + GL + L++G GW+ A LA+V+ GAA + E Sbjct: 193 PAAALDIPGALLVMGASIGLVWGLMRGSSKGWSDSE--APLALVV--GAAFMICFVLWER 248 Query: 268 RGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQLVPM 327 R P++P LFA+ F++ FL G+YG +F+L F Q +G D GL+L+P Sbjct: 249 RAKHPMIPMRLFASRAFSSGIAACFLFYAGMYGVVFFLPQFFQSAQGHDPFAAGLRLLPW 308 Query: 328 MAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTV-FTALAMGFSPATPYWLLALVCASANL 386 +FF ++G M G R ++ GL + + F +A SP T Y L + Sbjct: 309 TVTLFFIAPLAGSMVDRIGERSVMVTGLLLQAIGFAWIAWAASPGTSYLNLVAPLVISGA 368 Query: 387 GISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVAL 429 GIS A PA V+ A+ N R +G G+A+ Sbjct: 369 GISMAGPAAQKAVLGAVTVQDIGKASGVFNMFRILGGATGIAI 411 >Cgl1114 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 449 Score = 202 bits (515), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 140/406 (34%), Positives = 215/406 (52%), Gaps = 9/406 (2%) Query: 34 ALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLLVGGALADRFG 93 AL++G + +LD ++V V L I L A L+ VW+ Y LTFA LL+ G L DR+G Sbjct: 15 ALSVGLFLTLLDQSLVAVALPKIQEDLGASLNQAVWVSAVYLLTFAVPLLITGRLGDRYG 74 Query: 94 ARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYEDDRVR 153 R +YL G+ +F LA+L C AP+ +LIAAR +QGLG + P LS++ ++ DR R Sbjct: 75 QRNIYLAGMAVFTLAALACVFAPSIEWLIAARAVQGLGGSLLNPQPLSIIHKIFAHDR-R 133 Query: 154 ARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMARKLIPQVAGHA 213 GVWSA A GP++GGVL+ W+ WR+VFL+ VP+GL+ L M + +P++ Sbjct: 134 GAATGVWSAVASSAGLFGPVIGGVLVGWISWRAVFLVYVPLGLISLFMVARYVPKLPTGT 193 Query: 214 RALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALIRHELRGIAPL 273 ++ S +V + G+ L QGP GW + I LAV + A I + R APL Sbjct: 194 SKIDWLSGAVSLVAVLGVVLALQQGPELGWGT-LIWVSLAVGIAAAVLFIWMQTRSKAPL 252 Query: 274 LPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQLVPMMAVIFF 333 +P +F T FA F + F VY + L+LQ +G + GL LVPM + Sbjct: 253 MPLRIFKTRNFAIGAFSIFSLGFTVYSVNLPIMLYLQTAQGMSSQLAGLMLVPMGIISVV 312 Query: 334 GNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGFSPA--TPYWLL--ALVCASANLGIS 389 + + GR+ P + +G AL F A +P+WLL ++ S+N + Sbjct: 313 MSPVIGRLVDRLAPGMISKIGFGALIFSMALMAVFMIANLSPWWLLIPIILFGSSN---A 369 Query: 390 TAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILH 435 + + + ++ + SA+ N +RQ+GA++G A +GA++ Sbjct: 370 MSFAPNSVIALRDVPQDLVGSASGFYNTSRQVGAVLGAATLGAVMQ 415 >XF1765 [GEPR] COG0477 Permeases of the major facilitator superfamily Xfa Xylella fastidiosa 9a5c Length = 472 Score = 194 bits (492), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 151/432 (34%), Positives = 224/432 (51%), Gaps = 6/432 (1%) Query: 4 PSTPAAAALAAHPPAAGATLTPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAP 63 PS P AA+ A P A R L+A+ +GF + LD VVNV L +A L A Sbjct: 3 PSEPDAAS--ARAPDAPTPAAQRRAQATLIAVLLGFFVITLDAVVVNVALPTLAHDLGAS 60 Query: 64 LSTLVWIVDGYTLTFAAMLLVGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIA 123 + L W+VDGYTL F A+LL GAL DR GARR + GL +F+LAS+ CG AP L+ Sbjct: 61 VDGLQWVVDGYTLMFGALLLSAGALVDRIGARRAFGLGLVVFILASMACGGAPTLATLVV 120 Query: 124 ARLLQGLGAAFFMPSSLSLLTHVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLG 183 ARL+QG GAA MP+S+SL+ Y D R + +W+ +A+ GP++GG L+ L Sbjct: 121 ARLVQGAGAAVMMPASMSLIRQAYPDPVRRGHAVALWAMGGSVASTSGPVIGGWLVS-LD 179 Query: 184 WRSVFLINVPVGLVGLVMARKLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGW 243 WR +F +N+PVGL+ L + P A + + ++ + L + I+ G Sbjct: 180 WRWIFFVNLPVGLLTLAFLAR-TPASPRRASPFDAVGQVTAILAMGALIYGAIEAGAQGL 238 Query: 244 TSPRILAGLAVVLLAGAALIRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLF 303 + +LA + L A AA + + G P++P L A + +GF G +G F Sbjct: 239 GATPVLAAFVLALAALAAFVWSQRCGAHPMVPPGLLAPRNARISMAVGFTFMVGYFGLPF 298 Query: 304 YLALFLQQGRGADALQTGLQLVPMMAVIFFGNLMSGRMSAHWGPRVPLLLG-LSVGTVFT 362 ++L+LQQ RG A TG+ +PMM + S R++ +G R ++ G LS+ Sbjct: 299 VMSLYLQQHRGLSAPATGIAFLPMMLIGLVLTPFSARLAHRFGARTMIVSGLLSMAVGLA 358 Query: 363 ALAMGFSPATPYWLLALVCASANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIG 422 A+A + A W+ AL+ G A P ++ V G A A +A+ N +RQ+G Sbjct: 359 AVASLPASAPVGWIAALMVLVGLSGPFVAPPVAAVLLSSVPG-ALAGTASGVFNTSRQVG 417 Query: 423 ALVGVALMGAIL 434 + VA+ GA+L Sbjct: 418 GALAVAVFGALL 429 >Cgl1213 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 487 Score = 187 bits (476), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 138/443 (31%), Positives = 223/443 (50%), Gaps = 20/443 (4%) Query: 5 STPAAAALAAHPPAAGATLTPRAGMLP-LVALAIGFVMAMLDVTVVNVGLSNIAGSLDAP 63 ++ AA + A A A P P L+AL IGF M +LD T+V V + + A Sbjct: 9 TSSAAGSAAPQTKAYPAMPLPEKQAWPALIALCIGFFMILLDQTIVAVSTPALQADMGAS 68 Query: 64 LSTLVWIVDGYTLTFAAMLLVGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIA 123 + ++W+ Y LTFA LLV G L D++G + +Y+ G+ +F ++SL CG AP+ LI Sbjct: 69 YNEVIWVTSVYLLTFAVPLLVTGRLGDKYGPKNVYVAGMVIFTVSSLACGLAPDMFTLII 128 Query: 124 ARLLQGLGAAFFMPSSLSLLTHVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLG 183 AR +QGLGAA P +++ + ++ +R R LGVW +T GLA+ GP++GGV+ G Sbjct: 129 ARGVQGLGAALLTPQTMATINRIFAFER-RGAALGVWGSTAGLASLAGPILGGVITENWG 187 Query: 184 WRSVFLINVPVGLVGLVMARKLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGW 243 W+ VF INVP+G++ ++ K +P+ R L+ S + +V + L F +G GW Sbjct: 188 WQWVFYINVPIGVISVIAVMKYVPEFPPLTRPLDPLSIVLSIVAVFFLVFAFQEGEGAGW 247 Query: 244 TS---PRILAGLAVVLLAGAALIRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYG 300 + I+A A+ R E G PL+P +F F+ N + F V G Sbjct: 248 AAWVWIMIVAAFALFAWFIYQQSRAEKSGNDPLVPLEIFKFRNFSLGNICIMAMGFTVAG 307 Query: 301 NLFYLALFLQQGRGADALQTGLQLVP--MMAVIFFGNLMSGRMSAHWGPRVPLLLGLS-- 356 + L+ QQ G +A++ G +VP +MA + + G++ P + LG S Sbjct: 308 TPLPIMLYFQQAHGMNAMEAGFMMVPQALMAAVL--SPFVGKLVDRSNPGLMAALGFSTV 365 Query: 357 -VGTVFTALAMGFSPATPYWLLALVCASANLGISTAI---PAMTTVVMQVAGKAHANSAA 412 V V ++ M F + L+++ LGI A P T+ + + K + + Sbjct: 366 AVSIVLLSMVMIFDTGLVWALVSMTL----LGIGNAFVWAPNSTSTMRDLPHK-FMGAGS 420 Query: 413 AALNANRQIGALVGVALMGAILH 435 N RQ+G+++G A +GA++ Sbjct: 421 GVFNTTRQLGSVIGAAAIGAVMQ 443 >CAP0109 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 545 Score = 182 bits (462), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 121/418 (28%), Positives = 214/418 (51%), Gaps = 7/418 (1%) Query: 23 LTPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAML 82 + + ++ +A+ +GF M +LD T+VN+ L + + ++ + W+V+ Y L FA ++ Sbjct: 1 MNKKYQIISFIAIVLGFFMTLLDTTIVNITLPKMTEYFNTNMNHISWVVNAYNLAFAVII 60 Query: 83 LVGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSL 142 L LAD+FG +++++ G+FLF +ASLL G + + LI R LQGL AAF +P ++ L Sbjct: 61 LTASRLADQFGRKKIFIGGVFLFTIASLLAGISNSLEVLIFLRALQGLSAAFVVPVTMPL 120 Query: 143 LTHVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMA 202 ++ ++ R ++ +W A GLAAA GP +GG+L + WR +F INVP+G + + + Sbjct: 121 SAEIFPPEK-RGTIMSLWGAFAGLAAASGPTLGGILTQFFNWRYIFFINVPIGCLCIFLT 179 Query: 203 RKLIPQVAGHA--RALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGA 260 K I + A ++++ ++ + L+F LI+ GWTS L+ A + Sbjct: 180 IKFIKESYDQAASKSIDFGGNITISAAMFFLTFALIKVNEKGWTSSFTLSLFAASAITLI 239 Query: 261 ALIRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQT 320 I EL+ P+L +LF + QF + FL+ G+ ++L+ FL Q +G + L Sbjct: 240 IFIIIELKVNEPMLSLSLFKSLQFTNGSISLFLLGLGMMCGSYFLSFFLTQIKGLNELSA 299 Query: 321 GLQLVPMMAVIFFGNLMSGRMSAHWGPRVPLLLG--LSVGTVFTALAMGFSPATPYWLLA 378 GL + M F ++++ ++ G R G L + + ++ + + +L Sbjct: 300 GLIISTMSLSSMFFSIVAAILTKKVGKRFISAFGIFLLCFSCYLNSSLTQNSSNIDVILR 359 Query: 379 LVCASANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHS 436 L+ A G+S A +T+ K A+ N R +G ++GVAL I S Sbjct: 360 LIITGAGTGLSMATLLSSTIANVPINKIGI--ASGIDNMTRTLGTVLGVALFLTIFTS 415 >MT2395 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC Mycobacterium tuberculosis CDC1551 Length = 537 Score = 181 bits (459), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 132/410 (32%), Positives = 208/410 (50%), Gaps = 2/410 (0%) Query: 26 RAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLLVG 85 R +L L+A +G M LD +VNV L +I S L W+V Y+L A ++ Sbjct: 3 RTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSA 62 Query: 86 GALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTH 145 LAD +G RR YL G+ LF L S+ CG AP+ L AR QGLGAA +SL+L++ Sbjct: 63 ATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSA 122 Query: 146 VYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMARKL 205 + + + +AR +G+W+A + GP +GG+L+ GWRS+F +N+P+G + L + Sbjct: 123 AFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCY 182 Query: 206 IPQVAGH-ARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALIR 264 + + AR +LS L +V + L + +I+GP GWTS + + L + A + Sbjct: 183 VEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVW 242 Query: 265 HELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQL 324 E R P++ LF +A A + F VYG L FLQ RG TGL + Sbjct: 243 LERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMI 302 Query: 325 VPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGFSPATPYWLLALVCASA 384 +P A + + + G + G RVP+L GL + + + + FS L+ + Sbjct: 303 LPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLI-FSEHRSSALVLVGLGLC 361 Query: 385 NLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAIL 434 G++ + +TTV M A A+ ++A R IG+ +G A++G++L Sbjct: 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVL 411 >Rv2333c [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu Mycobacterium tuberculosis H37Rv Length = 537 Score = 179 bits (453), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 132/410 (32%), Positives = 207/410 (50%), Gaps = 2/410 (0%) Query: 26 RAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLLVG 85 R +L L+A +G M LD +VNV L +I S L W+V Y+L A ++ Sbjct: 3 RTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSA 62 Query: 86 GALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTH 145 LAD G RR YL G+ LF L S+ CG AP+ L AR QGLGAA +SL+L++ Sbjct: 63 ATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSA 122 Query: 146 VYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMARKL 205 + + + +AR +G+W+A + GP +GG+L+ GWRS+F +N+P+G + L + Sbjct: 123 AFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCY 182 Query: 206 IPQVAGH-ARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALIR 264 + + AR +LS L +V + L + +I+GP GWTS + + L + A + Sbjct: 183 VEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVW 242 Query: 265 HELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQL 324 E R P++ LF +A A + F VYG L FLQ RG TGL + Sbjct: 243 LERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMI 302 Query: 325 VPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGFSPATPYWLLALVCASA 384 +P A + + + G + G RVP+L GL + + + + FS L+ + Sbjct: 303 LPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLI-FSEHRSSALVLVGLGLC 361 Query: 385 NLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAIL 434 G++ + +TTV M A A+ ++A R IG+ +G A++G++L Sbjct: 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVL 411 >PA1316 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 513 Score = 177 bits (450), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 146/404 (36%), Positives = 220/404 (54%), Gaps = 5/404 (1%) Query: 34 ALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLLVGGALADRFG 93 A+ +G +A LD+++VN+ L + +LD L+ L W+VD Y L +A +L G L+DR+G Sbjct: 12 AIYLGTFIASLDISIVNLALPTLQYALDTDLAGLQWVVDAYALCLSAFMLSSGPLSDRYG 71 Query: 94 ARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYEDDRVR 153 + +L G+ LF SLLC A + P L+ R +QG+ A +P +LS+LT + D R Sbjct: 72 RKLTWLLGVGLFSFGSLLCALATSLPLLLFGRAVQGIAGALLIPGALSILTQAFHDPGQR 131 Query: 154 ARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMARKLIPQVA--G 211 A+++G W++ L+ +GPL+GG+L+ GW+S+FLIN+P+GL+ L + I + A Sbjct: 132 AQVIGGWTSFSALSLILGPLLGGLLVEHAGWQSIFLINLPLGLLALALGLWGIEETAHPE 191 Query: 212 HARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALIRHELRGIA 271 HA A + L VV L L++ LI GW SP L + + + E R Sbjct: 192 HA-AFDPLGQLLSVVWLGALTYALIAAGEGGWLSPTAWPALLLAGVGLLGFLFVERRTAR 250 Query: 272 PLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQLVPMMAVI 331 PLLP LF FA N F++ F Y +LF+L+LF QQ +GA A Q G L P + Sbjct: 251 PLLPLGLFRQAGFAVCNLASFVLGFSGYASLFFLSLFFQQVQGASAQQAGFYLAPQFLAM 310 Query: 332 FFGNLMSGRMSAHWGPRVPLLLG-LSVGTVFTALAMGFSPATPYWLLALVCASANLGIST 390 +++ GR+ H R L+LG L +G ALA T Y + L+ + LG+ Sbjct: 311 GALSMLFGRLQRHVPLRRLLVLGYLVIGLAMLALA-ACGTGTAYPWVGLLLVALGLGMGL 369 Query: 391 AIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAIL 434 A+P VM + + A+A +N RQ G VG+AL+GA+L Sbjct: 370 AVPGTGLAVMASVARERSGMASATMNTLRQAGMAVGIALLGALL 413