BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0038.p (598 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sll1180 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 481 e-135 RSp0292 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 470 e-132 all2676 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 465 e-130 XF2397 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, c... 464 e-130 all7315 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 464 e-130 alr1614 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 463 e-130 alr4239 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 447 e-125 NMA1620 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 435 e-121 NMB1400 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 434 e-121 VC1446 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, c... 427 e-119 >sll1180 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Syn Synechocystis Length = 1011 Score = 481 bits (1239), Expect = e-135, Method: Compositional matrix adjust. Identities = 255/576 (44%), Positives = 366/576 (63%), Gaps = 2/576 (0%) Query: 8 PETAEKDKRFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNL 67 P +RFGL L++ R + +AS +Q+F LA PL Q+IIDKV+ + Sbjct: 427 PSKDTPQQRFGLSWFWPALVKYRYILLLVFVASFFVQLFGLANPLMIQIIIDKVIVQNSK 486 Query: 68 ASLHVLGVAMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPI 127 +L VLG+A++ + FEA S LR L ++RID LG ++ HLLRLPLRYFE+RP+ Sbjct: 487 DTLQVLGIALVSIAIFEALLSTLRTYLFVDTTNRIDMSLGSEIIDHLLRLPLRYFENRPV 546 Query: 128 GILLSQAKEMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFS 187 G + ++ E+E+IRQ L G++ + ++D +F+VV+I VM YS LT V L VP+ ++ + Sbjct: 547 GEISTRVNELENIRQFLTGTALTVVLDSVFSVVYIVVMIIYSPLLTAVALGIVPIFVILT 606 Query: 188 LAVRPLMRRTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAAR 247 L PL+RR L K E ++ S L+E++SGI +KA IE + +WQ S V A Sbjct: 607 LVFSPLIRRQLRLKAERNAQTQSYLVEVMSGIQTVKAQNIELRSRWQWQDKYSRYVGAGF 666 Query: 248 QASGFSSMNAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVV 307 S++ ++ + + + L VLW+GA LVLDG LT+GQ+IAF+++A P+ + Sbjct: 667 NTVITSTLASSSSHFLNQLSGLLVLWVGASLVLDGDLTLGQLIAFRIIAGYVTSPILRLT 726 Query: 308 QVWQELQQLSLSSDELGQIMNVPSEDDSGVTR-AAAEMRGDVQLVDLGFRYSPQSPVVLD 366 Q+WQ Q+ +LS + L I++ P E + E+ G+V+ ++ FR+ Q P+ L+ Sbjct: 727 QLWQNFQETALSLERLADIVDTPQESERDRQNIPMPEIAGEVKFENVSFRFKKQGPLQLN 786 Query: 367 GISLVAGPGDIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQIS 426 I+L PG + +VG+SG GKSTL KLL LY P G+IL+DG+DIG +L +LR Q+ Sbjct: 787 NINLSFPPGTFVALVGQSGAGKSTLTKLLSRLYEPEGGRILVDGLDIGKVELYSLRRQVG 846 Query: 427 VVPQDIFLFSGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGIL 486 VVPQ+ LF G++ ENIA+++ E I++AA++A AH FIM LP GY+T VGERG Sbjct: 847 VVPQETLLFEGTVQENIALTNPDATTEQIISAAKVASAHEFIMTLPNGYNTRVGERGAT- 905 Query: 487 LSGGQRQKIAIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLS 546 LSGGQRQ+IAIAR+V RPRIL+LDEATSALD+ +E +V L +AF TVF I HRLS Sbjct: 906 LSGGQRQRIAIARSVLQRPRILVLDEATSALDYITEQQVCINLGDAFKDHTVFFITHRLS 965 Query: 547 TIRHASKILVLEQGRFVEAGKHDELMQQDGLYRRLY 582 ++R A I++++QG VE G HDELM G Y LY Sbjct: 966 SVRSADVIVMMDQGSVVEQGSHDELMALKGRYYYLY 1001 >RSp0292 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Rso Ralstonia solanacearum Length = 725 Score = 470 bits (1210), Expect = e-132, Method: Compositional matrix adjust. Identities = 249/570 (43%), Positives = 365/570 (64%), Gaps = 3/570 (0%) Query: 16 RFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNLASLHVLGV 75 +F + +++ R E+LL SL LQI L P+F QV++DKVL + + +L+V+ V Sbjct: 152 KFDFTWFIPAVIKYRKLLGEVLLVSLTLQIIGLVTPMFFQVVMDKVLVNHAMKTLNVIAV 211 Query: 76 AMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPIGILLSQAK 135 +I I FE + +R + + SS+ID LG R+ RHLL LPL YF+SR +G +++ + Sbjct: 212 GLICAILFEVTLTSIRTWVFAHTSSKIDVELGARLFRHLLSLPLAYFQSRRVGDSVARVR 271 Query: 136 EMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFSLAVRPLMR 195 E+E+IR L G++ + ++DL+F+ VF+AVM YS LTL+V++++P+ I S P++R Sbjct: 272 ELENIRSFLTGNAMTVVLDLLFSFVFLAVMLWYSVWLTLIVVVSIPLYIGLSAVFTPIIR 331 Query: 196 RTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAARQASGFSSM 255 L K + S L+E ISGI +KA+A+E +W Q L+ V A + +++ Sbjct: 332 ARLDVKFNRNAENQSFLVETISGIDTVKAMAVEPRWTHKWDQQLAAYVTAGLAVTNVATV 391 Query: 256 NAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVVQVWQELQQ 315 + LV + + A++WLGA LV+D ++TVG+++AF MLA + P+ + Q+W + QQ Sbjct: 392 ASGGVTLVSKLVTAAIMWLGATLVIDHKMTVGELVAFNMLAGQVSSPILRLAQLWNDFQQ 451 Query: 316 LSLSSDELGQIMNVPSEDDSGVTRAAAEMRGDVQLVDLGFRYSPQSPVVLDGISLVAGPG 375 + +S LG I+N +E +G ++ G + + FRY P +P V+ GISL PG Sbjct: 452 VGISMSRLGDILNARTE-VAGQKSRLPKLAGAIAFDQVAFRYRPDAPDVIRGISLAIAPG 510 Query: 376 DIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQISVVPQDIFLF 435 ++IGIVGRSG GKSTL KL+ LY P +G++LIDG DI D +LR QI VV Q+ LF Sbjct: 511 EVIGIVGRSGSGKSTLTKLVQRLYVPERGRVLIDGQDIAIVDTTSLRQQIGVVLQENTLF 570 Query: 436 SGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGILLSGGQRQKI 495 S SI +NIA+++ LEAI+ AA LA AH FI LP+GYDT+VGE G LSGGQRQ+I Sbjct: 571 SRSIRDNIALTNPAAPLEAIIEAARLAGAHEFICELPEGYDTIVGEH-GTGLSGGQRQRI 629 Query: 496 AIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLSTIRHASKIL 555 AIARA+ PRILI DEATSALD+ESE +Q +R TV +IAHRLS +R A++I+ Sbjct: 630 AIARALLTNPRILIFDEATSALDYESEKIIQDNMRRICQGRTVLIIAHRLSAVREANRII 689 Query: 556 VLEQGRFVEAGKHDELMQQ-DGLYRRLYTM 584 V+E+G+ E G HD+L++ G+Y LY + Sbjct: 690 VMERGQIAEMGSHDQLLKHPQGIYAHLYAL 719 >all2676 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Nos Nostoc sp. PCC 7120 Length = 989 Score = 465 bits (1197), Expect = e-130, Method: Compositional matrix adjust. Identities = 258/582 (44%), Positives = 363/582 (62%), Gaps = 4/582 (0%) Query: 8 PETAEKDKRFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNL 67 P KRFGL + + + R +E+L++S +Q+F LA PL +QVIIDKVL + Sbjct: 408 PTKETPRKRFGLSWFLPFVSQYRRVLSEVLISSFFVQLFGLANPLITQVIIDKVLIQNSP 467 Query: 68 ASLHVLGVAMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPI 127 A+L+VLG ++ FEA + LR L ++RID LG V+ HLLRLPL YFE RP+ Sbjct: 468 ATLNVLGTLLVATALFEAVLTTLRTNLFVETTNRIDMALGSEVINHLLRLPLGYFEKRPV 527 Query: 128 GILLSQAKEMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFS 187 G L ++ E+E+IRQ L G++ + ++D IF+V++I VM YS LTLV L VP+ + Sbjct: 528 GELSTRINELENIRQFLTGTALTVVLDAIFSVIYIVVMLYYSWLLTLVALATVPLFALLG 587 Query: 188 LAVRPLMRRTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAAR 247 + V P++R+ + E ++ S L+E++SGI +KA IE + +WQ + VA + Sbjct: 588 VIVAPVIRQQTRTRAERNAQTQSYLVEVVSGIQTVKAQNIELRSRWQWQDRYARYVADSF 647 Query: 248 QASGFSSMNAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVV 307 + + S+ + + + + L +LW+GA LVL G LT+GQ+IAF+++A P+ +V Sbjct: 648 KNALTSTTAGSISKFLNQLSGLLLLWVGAFLVLQGTLTLGQLIAFRIIAGYTTSPLLRLV 707 Query: 308 QVWQELQQLSLSSDELGQIMNVPSEDDSGVTRAAAEMRGDVQLVDLGFRYSPQSPVVLDG 367 Q+WQ Q+ +LS + L I++ P E+ +++G V+ + FR++ LD Sbjct: 708 QLWQNFQETALSLERLSDILDTPQEEAVRQDIPLPDIQGAVKYDHITFRFTNSPTPQLDN 767 Query: 368 ISLVAGPGDIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQISV 427 ISL PG +G+VG+SG GKSTL KLL LY P G+ILIDG DI +L +LR QI + Sbjct: 768 ISLDIPPGKFVGVVGQSGAGKSTLTKLLTRLYDPEVGRILIDGYDIHKVELYSLRRQIGM 827 Query: 428 VPQDIFLFSGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGILL 487 V QD LF ++ ENIA+++ E I+ AA++A AH FIM+LP GY+T VGERG L Sbjct: 828 VLQDTLLFDTTVQENIALNNPEATPEEIINAAKIAYAHEFIMSLPMGYNTRVGERGSA-L 886 Query: 488 SGGQRQKIAIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLST 547 SGGQRQ+IAIAR V PR+LI+DEATSALD+ SE +V L++A TVF I HRL T Sbjct: 887 SGGQRQRIAIARTVLQNPRLLIMDEATSALDYNSERQVCQNLQQALEGRTVFFITHRLGT 946 Query: 548 IRHASKILVLEQGRFVEAGKHDELMQQDGLYRRLYTMDAQQE 589 IRHA IL++EQGR E G HDELM GLY LY QQE Sbjct: 947 IRHADIILMMEQGRIAEQGTHDELMALRGLYYCLY---RQQE 985 >XF2397 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Xfa Xylella fastidiosa 9a5c Length = 720 Score = 464 bits (1195), Expect = e-130, Method: Compositional matrix adjust. Identities = 250/570 (43%), Positives = 370/570 (64%), Gaps = 3/570 (0%) Query: 16 RFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNLASLHVLGV 75 +F + +++ R AE+ SL +QIFAL PLF QV++DKVL H+ L++L V+ V Sbjct: 148 KFDFSWFIPAVVKYRKLLAEVFAVSLFIQIFALVTPLFYQVVMDKVLVHQALSTLEVIVV 207 Query: 76 AMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPIGILLSQAK 135 +I L FE + LR + + +S+ID LG R+ RHLL LPL YFESR +G +++ + Sbjct: 208 GLISLALFEVLLTTLRTHVFAHTTSKIDVELGARLFRHLLALPLAYFESRRVGDTIARVR 267 Query: 136 EMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFSLAVRPLMR 195 E+E+IR L G + + ++DL+FTVVF++VMF YS+ LTL+V++++P+ + S + P++R Sbjct: 268 ELENIRHFLTGQALTSVLDLLFTVVFLSVMFWYSSWLTLIVVISLPLYALISAFITPVLR 327 Query: 196 RTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAARQASGFSSM 255 + L K + + L+E +SGI +KA+A++ + W L+ V A+ + +++ Sbjct: 328 KRLDEKFARGADNQAFLVETVSGIGTVKAMAVDPRVTRTWDNQLAGYVGASFSVTKIATL 387 Query: 256 NAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVVQVWQELQQ 315 LVQ+ +AVL+ GA LV+DGQL++GQ+IAF ML+ + P+ + Q+WQ+ QQ Sbjct: 388 GQQSVQLVQKLTNVAVLFWGAKLVIDGQLSLGQLIAFNMLSGQVTAPIIRLAQLWQDFQQ 447 Query: 316 LSLSSDELGQIMNVPSEDDSGVTRAAAEMRGDVQLVDLGFRYSPQSPVVLDGISLVAGPG 375 + LS + LG+I+N +E G ++G + L FRY P +P VL GI L PG Sbjct: 448 VGLSVERLGEILNTRTE-LPGSRMTLPPIQGRITFERLIFRYRPDTPDVLAGIDLDIQPG 506 Query: 376 DIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQISVVPQDIFLF 435 ++IGIVGRSG GKSTL KL+ +Y P +G++L+D D+ D LR QI VV Q+ FLF Sbjct: 507 EVIGIVGRSGSGKSTLTKLVQRMYVPERGRVLVDSHDLSLADPAWLRRQIGVVLQENFLF 566 Query: 436 SGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGILLSGGQRQKI 495 + S+ ENIA++D LE ++ AA LA AH FI LP+GYDT +GE G LSGGQRQ+I Sbjct: 567 NRSVRENIAMADPGIPLERVIHAATLAGAHPFIAELPEGYDTKIGEH-GTGLSGGQRQRI 625 Query: 496 AIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLSTIRHASKIL 555 AIARA+ PRILI DEATSALD+ESE V +R TV +IAHRLST+R+A +I+ Sbjct: 626 AIARALIGDPRILIFDEATSALDYESEHAVMQNMRAICKGRTVLIIAHRLSTVRNADRIV 685 Query: 556 VLEQGRFVEAGKHDELM-QQDGLYRRLYTM 584 V+++G+ VE+G H+ L+ + +G Y LY + Sbjct: 686 VIDKGKIVESGSHETLLNRNNGHYAHLYRL 715 >all7315 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Nos Nostoc sp. PCC 7120 Length = 975 Score = 464 bits (1195), Expect = e-130, Method: Compositional matrix adjust. Identities = 260/591 (43%), Positives = 367/591 (62%), Gaps = 6/591 (1%) Query: 3 ELDVLPETAEKDK-RFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKV 61 E+ +L T K RF L + + R E+L+AS+ +QIF L PL +QVIIDKV Sbjct: 389 EVLLLQTTKNTPKSRFNLSWFVPAIKRHRKVLIEVLIASIVIQIFGLVNPLVTQVIIDKV 448 Query: 62 LNHRNLASLHVLGVAMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRY 121 L + +L V G+ ++V+ EA + +R L ++RID LG V+ HLLRLPL Y Sbjct: 449 LVGNSPDTLEVFGIFLLVIAVIEAILTTVRTHLFVDTTNRIDLSLGSEVINHLLRLPLSY 508 Query: 122 FESRPIGILLSQAKEMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVP 181 FE P+G L ++ E+E+IR L G++ + ++D +F+VV+I VM YS LTLV L+ VP Sbjct: 509 FERHPVGELATRIHELENIRSFLTGTALTVVMDAVFSVVYIVVMAFYSPILTLVALVTVP 568 Query: 182 VLIVFSLAVRPLMRRTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSE 241 + + +L V PLMRR L K E + S L+E++ G+ +KA +E + +WQ+ + Sbjct: 569 LFGLLNLIVSPLMRRQLQEKAERNAETQSYLVEVMGGMQTVKAQNLEMRSRWQWQERYAR 628 Query: 242 QVAAARQASGFSSMNAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIH 301 ++A + + ++F+ + + + VLW+GA+LVL+ QLT+GQ+IAF++LA Sbjct: 629 YISAGFKTVSTQTTASSFSSFLNKFSSMLVLWVGAYLVLNQQLTLGQLIAFRILAGYVTS 688 Query: 302 PVTHVVQVWQELQQLSLSSDELGQIMNVPSEDDSGVTRA-AAEMRGDVQLVDLGFRYSPQ 360 P+ ++Q+WQ Q+ +LS L +I++ P E ++ ++G+V+ +L F + Sbjct: 689 PLLRLMQLWQNFQETALSLQRLAEILDSPQETETETQNILMPSIQGNVRYENLSFSFLEH 748 Query: 361 SPVVLDGISLVAGPGDIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLT 420 P+ L I+L G IGIVG+SG GKSTL KLL LY P GKILIDG DI +L + Sbjct: 749 GPLQLSNINLDFPAGSFIGIVGQSGSGKSTLLKLLPRLYEPKSGKILIDGYDIAKVELYS 808 Query: 421 LRAQISVVPQDIFLFSGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVG 480 LR QI +V QD LF G++ ENIA+ E I+AAA++A AH FIM LP GY+T VG Sbjct: 809 LRRQIGMVLQDTLLFDGTVRENIALGSSEASDEEIIAAAKVAFAHDFIMDLPIGYNTRVG 868 Query: 481 ERGGILLSGGQRQKIAIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFV 540 ERG LSGGQRQ+IAIAR V P++LILDEATSALD+ +E++V L AF TVF Sbjct: 869 ERGSG-LSGGQRQRIAIARTVLQNPQLLILDEATSALDYNAEAQVGRNLATAFQGKTVFF 927 Query: 541 IAHRLSTIRHASKILVLEQGRFVEAGKHDELMQQDGLYRRLYTMDAQQEQR 591 I HRLSTIRHA+ IL++EQG VE G H+ELM + G Y LY QQE R Sbjct: 928 ITHRLSTIRHANIILMMEQGAVVEQGTHEELMARKGYYYCLY---QQQETR 975 >alr1614 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Nos Nostoc sp. PCC 7120 Length = 893 Score = 463 bits (1192), Expect = e-130, Method: Compositional matrix adjust. Identities = 249/574 (43%), Positives = 357/574 (62%), Gaps = 1/574 (0%) Query: 9 ETAEKDKRFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNLA 68 E K ++F L + + R AE+LLAS LQ+ L PL +QV+IDKV+ +L Sbjct: 314 ELISKQEKFNLSWFTPAVWKYRKLLAEVLLASFTLQLLGLGTPLITQVVIDKVMVQESLP 373 Query: 69 SLHVLGVAMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPIG 128 +L V+ +A++++ FE+ ILR + + + R+D L ++ RHL+RLPL YFESR +G Sbjct: 374 TLDVMAIALLLIAVFESILGILRLFIFTHTARRLDLSLSAQLFRHLMRLPLAYFESRRVG 433 Query: 129 ILLSQAKEMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFSL 188 +++ +E+E IRQ L G++ + ++D IF VV++A+MF Y+ LT V L +P+ ++ Sbjct: 434 DTVARVQELEQIRQFLTGTALTVILDSIFAVVYLALMFYYNIPLTFVALAVLPLFATLTI 493 Query: 189 AVRPLMRRTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAARQ 248 P++R L ++ + S L+E ++GIH++KA A E+ + RW+ + V + Sbjct: 494 VATPILRNWLNETFNRSADSQSFLVETVTGIHSVKAHAAESVARDRWEGLFARFVRTGFK 553 Query: 249 ASGFSSMNAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVVQ 308 AS S++++ + L +LW GA LV+D +LT+GQ++AFQML+ R P+ +VQ Sbjct: 554 ASTTSNISSNIGDFLTNFSSLLILWFGAKLVIDQKLTIGQLVAFQMLSGRVTGPLLRLVQ 613 Query: 309 VWQELQQLSLSSDELGQIMNVPSEDDSGVTRAAAEMRGDVQLVDLGFRYSPQSPVVLDGI 368 +WQ LQQ+ LS D +G I+NV E + G ++G V + FRY + VL GI Sbjct: 614 LWQNLQQVLLSVDRIGDILNVAPEAEMGTGLVLPPLKGQVSFEQIFFRYKTNTEPVLRGI 673 Query: 369 SLVAGPGDIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQISVV 428 S PG +GIVGRSG GKSTL+KLL LY+ G+ILIDG DI DL +LR QI VV Sbjct: 674 SFNVEPGQFVGIVGRSGSGKSTLSKLLQRLYQIESGRILIDGFDIKSADLSSLRQQIGVV 733 Query: 429 PQDIFLFSGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGILLS 488 Q+ FLF+GSI ENI + + E +V AA LA AH FI LP GY+T VGER G LS Sbjct: 734 LQEDFLFNGSILENITLGNPDITAEQVVEAARLAVAHDFISQLPYGYETNVGER-GTALS 792 Query: 489 GGQRQKIAIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLSTI 548 GGQRQ+IA+AR + IL+LDEATSALD E+E +V L++ + TVF+IAHR + + Sbjct: 793 GGQRQRIALARLFLSDSPILVLDEATSALDSETEQQVLQNLQKISANRTVFLIAHRFAPL 852 Query: 549 RHASKILVLEQGRFVEAGKHDELMQQDGLYRRLY 582 + A ILVLE+G E G H EL+QQ GLY LY Sbjct: 853 KRADLILVLEKGVIAERGTHPELLQQKGLYWSLY 886 >alr4239 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Nos Nostoc sp. PCC 7120 Length = 1003 Score = 447 bits (1150), Expect = e-125, Method: Compositional matrix adjust. Identities = 250/576 (43%), Positives = 364/576 (63%), Gaps = 5/576 (0%) Query: 15 KRFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNLASLHVLG 74 +RFGLR + L R E+ +AS +Q+ ALA PL Q+IIDKV+ ++++L+VLG Sbjct: 429 ERFGLRWFIPYLSRYRRVLIEVFIASFFVQLAALANPLVIQLIIDKVIVQNSISTLNVLG 488 Query: 75 VAMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPIGILLSQA 134 V ++ + FEA + LR L ++RID LG ++ HLLRLPLRYFE RP+G L ++ Sbjct: 489 VLLLAVGVFEAVLTTLRTYLFVDTTNRIDMGLGSEIIDHLLRLPLRYFEKRPVGELATRI 548 Query: 135 KEMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFSLAVRPLM 194 E+E+IRQ L G++ + +D +F+VV+I VM YS LTLV L +P+ I+ +L P + Sbjct: 549 NELENIRQFLTGTALTVGLDAVFSVVYIIVMLFYSWQLTLVGLGTIPIFIIITLIASPTV 608 Query: 195 RRTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAARQASGFSS 254 R L K E S S L+E++SGI +KA IE + WQ+ + VAA + S+ Sbjct: 609 SRQLRSKAERNSETQSYLVEVMSGIQTVKAQNIELRSRFSWQERYARYVAAGFKTVITST 668 Query: 255 MNAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVVQVWQELQ 314 + + + + + L VLW+GA+LVL G+LT+G++IAF++++ P+ + Q+WQ Q Sbjct: 669 LANSTSQFLNKLSSLLVLWVGAYLVLQGELTLGELIAFRIISGYVTSPILRLAQLWQSFQ 728 Query: 315 QLSLSSDELGQIMNVPSEDD-SGVTRAAAEMRGDVQLVDLGFRYSPQSPVVLDGISLVAG 373 + +LS + L I++ P E + E++G V+ ++ FR++P P+ L ++L Sbjct: 729 ETALSLERLSDIVDTPQEAEIDRYNIPLPEIQGSVKYENISFRFAPSGPLQLSNVNLEIP 788 Query: 374 PGDIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQISVVPQDIF 433 G IGIVG+SG GKST+ KLL LY G+ILIDG DI +L +LR Q+ VVPQ+ Sbjct: 789 SGKFIGIVGQSGSGKSTMMKLLLRLYDVESGRILIDGYDIAKVELYSLRRQVGVVPQETL 848 Query: 434 LFSGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGILLSGGQRQ 493 LF G++ ENIA+++ + I+ AA +A AH FIM+LP GY+T VGERG LSGGQRQ Sbjct: 849 LFDGTVQENIALTNPDASTDEIIEAARVAAAHEFIMSLPNGYNTRVGERGA-GLSGGQRQ 907 Query: 494 KIAIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLSTIRHASK 553 +IAIAR+V RP++L+LDEATSALD+ +E +V L +AF TVF I HRL+T+ HA Sbjct: 908 RIAIARSVLQRPKLLVLDEATSALDYPTERQVCLNLAKAFQGSTVFFITHRLNTVSHADM 967 Query: 554 ILVLEQGRFVEAGKHDELMQQDGLYRRLYTMDAQQE 589 I+V++ G+ +E G H ELM G Y LY QQE Sbjct: 968 IVVMDAGKVIEQGSHQELMAAKGHYFYLY---QQQE 1000 >NMA1620 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain NmA Neisseria meningitidis Z2491 Length = 742 Score = 435 bits (1119), Expect = e-121, Method: Compositional matrix adjust. Identities = 245/570 (42%), Positives = 364/570 (63%), Gaps = 3/570 (0%) Query: 16 RFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNLASLHVLGV 75 +F + +++ R E+L+ S+ LQ+FAL PLF QV++DKVL HR ++L V+ V Sbjct: 172 KFDFTWFIPAVIKYRRLFFEVLVVSVVLQLFALITPLFFQVVMDKVLVHRGFSTLDVVSV 231 Query: 76 AMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPIGILLSQAK 135 A++V+ FE LR L + +SRID LG R+ RHLL LPL YFE R +G +++ + Sbjct: 232 ALLVVSLFEIVLGGLRTYLFAHTTSRIDVELGARLFRHLLSLPLSYFEHRRVGDTVARVR 291 Query: 136 EMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFSLAVRPLMR 195 E+E IR L G + + ++DL F+ +F+AVM+ YS+TLT VVL ++P +S + P++R Sbjct: 292 ELEQIRNFLTGQALTSVLDLAFSFIFLAVMWYYSSTLTWVVLASLPAYAFWSAFISPILR 351 Query: 196 RTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAARQASGFSSM 255 L K + S L+E I+ + +KA+A+E M RW L+ VA+ + + + + Sbjct: 352 TRLNDKFARNADNQSFLVESITAVGTVKAMAVEPQMTQRWDNQLAAYVASGFRVTKLAVV 411 Query: 256 NAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVVQVWQELQQ 315 L+Q+ + +A LW+GA LV++ +LTVGQ+IAF ML+ + PV + Q+WQ+ QQ Sbjct: 412 GQQGVQLIQKLVTVATLWIGARLVIESKLTVGQLIAFNMLSGQVAAPVIRLAQLWQDFQQ 471 Query: 316 LSLSSDELGQIMNVPSEDDSGVTRAAAEMRGDVQLVDLGFRYSPQSPVVLDGISLVAGPG 375 + +S LG I+N P+E+ S A ++RG++ + FRY ++L ++L G Sbjct: 472 VGISVARLGDILNAPTENASS-HLALPDIRGEITFEHVDFRYKADGRLILQDLNLRIRAG 530 Query: 376 DIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQISVVPQDIFLF 435 +++GIVGRSG GKSTL KL+ LY P QG++L+DG D+ LR Q+ VV Q+ L Sbjct: 531 EVLGIVGRSGSGKSTLTKLVQRLYVPAQGRVLVDGNDLALAAPAWLRRQVGVVLQENVLL 590 Query: 436 SGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGILLSGGQRQKI 495 + SI +NIA++D LE I+ AA+LA AH FIM LP+GY TVVGE+G LSGGQRQ+I Sbjct: 591 NRSIRDNIALTDTGMPLERIIEAAKLAGAHEFIMELPEGYGTVVGEQGA-GLSGGQRQRI 649 Query: 496 AIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLSTIRHASKIL 555 AIARA+ PRILI DEATSALD+ESE + ++ + TV +IAHRLST++ A +I+ Sbjct: 650 AIARALITNPRILIFDEATSALDYESERAIMQNMQAICANRTVLIIAHRLSTVKTAHRII 709 Query: 556 VLEQGRFVEAGKHDELM-QQDGLYRRLYTM 584 +++GR VEAG EL+ + +G YR LY + Sbjct: 710 AMDKGRIVEAGTQQELLAKPNGYYRYLYDL 739 >NMB1400 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Nme Neisseria meningitidis MC58 Length = 742 Score = 434 bits (1117), Expect = e-121, Method: Compositional matrix adjust. Identities = 245/570 (42%), Positives = 364/570 (63%), Gaps = 3/570 (0%) Query: 16 RFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNLASLHVLGV 75 +F + +++ R E+L+ S+ LQ+FAL PLF QV++DKVL HR ++L V+ V Sbjct: 172 KFDFTWFIPAVIKYRRLFFEVLVVSVVLQLFALITPLFFQVVMDKVLVHRGFSTLDVVSV 231 Query: 76 AMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPIGILLSQAK 135 A++V+ FE LR L + +SRID LG R+ RHLL LPL YFE R +G +++ + Sbjct: 232 ALLVVSLFEIVLGGLRTYLFAHTTSRIDVELGARLFRHLLSLPLSYFEHRRVGDTVARVR 291 Query: 136 EMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFSLAVRPLMR 195 E+E IR L G + + ++DL F+ +F+AVM+ YS+TLT VVL ++P +S + P++R Sbjct: 292 ELEQIRNFLTGQALTSVLDLAFSFIFLAVMWYYSSTLTWVVLASLPAYAFWSAFISPILR 351 Query: 196 RTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAARQASGFSSM 255 L K + S L+E I+ + +KA+A+E M RW L+ VA+ + + + + Sbjct: 352 TRLNDKFARNADNQSFLVESITAVGTVKAMAVEPQMTQRWDNQLAAYVASGFRVTKLAVV 411 Query: 256 NAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVVQVWQELQQ 315 L+Q+ + +A LW+GA LV++ +LTVGQ+IAF ML+ + PV + Q+WQ+ QQ Sbjct: 412 GQQGVQLIQKLVTVATLWIGARLVIESKLTVGQLIAFNMLSGQVAAPVIRLAQLWQDFQQ 471 Query: 316 LSLSSDELGQIMNVPSEDDSGVTRAAAEMRGDVQLVDLGFRYSPQSPVVLDGISLVAGPG 375 + +S LG I+N P+E+ S A ++RG++ + FRY ++L ++L G Sbjct: 472 VGISVARLGDILNAPTENASS-HLALPDIRGEITFEHVDFRYKADGRLILQDLNLRIRAG 530 Query: 376 DIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQISVVPQDIFLF 435 +++GIVGRSG GKSTL KL+ LY P QG++L+DG D+ LR Q+ VV Q+ L Sbjct: 531 EVLGIVGRSGSGKSTLTKLVQRLYVPEQGRVLVDGNDLALAAPAWLRRQVGVVLQENVLL 590 Query: 436 SGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGILLSGGQRQKI 495 + SI +NIA++D LE I+ AA+LA AH FIM LP+GY TVVGE+G LSGGQRQ+I Sbjct: 591 NRSIRDNIALTDTGMPLERIIEAAKLAGAHEFIMELPEGYGTVVGEQGA-GLSGGQRQRI 649 Query: 496 AIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLSTIRHASKIL 555 AIARA+ PRILI DEATSALD+ESE + ++ + TV +IAHRLST++ A +I+ Sbjct: 650 AIARALITNPRILIFDEATSALDYESERAIMQNMQAICANRTVLIIAHRLSTVKTAHRII 709 Query: 556 VLEQGRFVEAGKHDELM-QQDGLYRRLYTM 584 +++GR VEAG EL+ + +G YR LY + Sbjct: 710 AMDKGRIVEAGTQQELLAKPNGYYRYLYDL 739 >VC1446 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Vch Vibrio cholerae Length = 721 Score = 427 bits (1099), Expect = e-119, Method: Compositional matrix adjust. Identities = 242/573 (42%), Positives = 357/573 (62%), Gaps = 5/573 (0%) Query: 13 KDKRFGLRELMRPLLEKRTAAAEILLASLALQIFALAVPLFSQVIIDKVLNHRNLASLHV 72 K+ +FGL +L +++ ++ L ++ALQIFAL P+ + +IDKVL R+L+SLHV Sbjct: 147 KEVKFGLSWFAPSILRQKSQLRDVFLYAIALQIFALVSPMLFENVIDKVLVGRSLSSLHV 206 Query: 73 LGVAMIVLIGFEAAFSILRARLLDYLSSRIDALLGMRVVRHLLRLPLRYFESRPIGILLS 132 L +AM+ L E A+S LR + +L+S+++A L R+ RHL+ LPL YF+ R G +++ Sbjct: 207 LALAMLALAIAEPAYSYLRNTVFGHLASQVNAELSGRLYRHLVGLPLTYFKQRQTGQIIA 266 Query: 133 QAKEMESIRQILAGSSFSGLVDLIFTVVFIAVMFSYSTTLTLVVLLAVPVLIVFSLAVRP 192 + +EM IRQ L GS+ L+DLIF VF+AVMF Y++TLT +V+ ++ + V L P Sbjct: 267 RVREMAQIRQFLTGSTLMLLLDLIFVTVFLAVMFHYASTLTWLVIGSLVIYFVLWLIAGP 326 Query: 193 LMRRTLARKHEMASRAGSVLLELISGIHAIKALAIETAMQSRWQQALSEQVAAA--RQAS 250 L+R+ + ++E + A + L E ++GI IK A E +WQ+ LS+Q+ + Q S Sbjct: 327 LIRKKVESEYESDANATTFLTEAVTGIETIKTTATEHRFLEQWQRILSQQLNRSFDAQKS 386 Query: 251 GFSSMNAAFNLLVQRALVLAVLWLGAHLVLDGQLTVGQVIAFQMLALRFIHPVTHVVQVW 310 G + A LVQ+ +LW G VL G++T GQ++AF MLA PV + Q+W Sbjct: 387 GLIAGQAI--ALVQKLTAALLLWWGVSAVLKGEITPGQLVAFNMLAGHVTQPVLRLAQIW 444 Query: 311 QELQQLSLSSDELGQIMNVPSEDDSGVTRAAAEMRGDVQLVDLGFRYSPQSPVVLDGISL 370 Q+ Q ++ +G I++ P E+ + E+ G ++ ++ FRY +P VL +SL Sbjct: 445 QDFQHTLIALRRVGDILDEPRENSKQGLASVPELDGGIEFSNIRFRYHQDAPEVLANLSL 504 Query: 371 VAGPGDIIGIVGRSGGGKSTLAKLLHGLYRPTQGKILIDGVDIGHHDLLTLRAQISVVPQ 430 PG IG+ G SG GKSTL +LL LY P G++L+DG+D+ D ++LR +SVV Q Sbjct: 505 KIKPGQFIGVTGPSGSGKSTLTRLLQRLYVPQHGQVLVDGMDLAIADPVSLRRNMSVVLQ 564 Query: 431 DIFLFSGSIAENIAISDGHTDLEAIVAAAELADAHTFIMALPQGYDTVVGERGGILLSGG 490 + LFSGS+A+NI + E I AA+LA A FI LP G++ VGE+G LSGG Sbjct: 565 ESILFSGSVADNIRLCKPQASDEEIRHAAQLAGALAFIEGLPHGFNQPVGEKGAA-LSGG 623 Query: 491 QRQKIAIARAVYARPRILILDEATSALDHESESRVQGKLREAFPHCTVFVIAHRLSTIRH 550 QRQ+IA+ARA+ PRIL+LDEATSALD+ SE+ + + E TV IAHRL+TIRH Sbjct: 624 QRQRIALARALLVNPRILLLDEATSALDYNSEASIMSNMDEICRGRTVISIAHRLNTIRH 683 Query: 551 ASKILVLEQGRFVEAGKHDELMQQDGLYRRLYT 583 A I VL++G+ E+G H+EL+ Q GLY +L+T Sbjct: 684 ADNIFVLDKGQVAESGTHEELLAQQGLYAKLWT 716