BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0132.p (561 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2889 [S] COG1289 Predicted membrane protein Rso Ralstonia sol... 486 e-137 PA0454 [S] COG1289 Predicted membrane protein Pae Pseudomonas ae... 147 9e-35 ECs1044 [S] COG1289 Predicted membrane protein Ecs Escherichia c... 138 4e-32 yccS [S] COG1289 Predicted membrane protein Eco Escherichia coli... 137 5e-32 YPO1438 [S] COG1289 Predicted membrane protein Ype Yersinia pestis 137 7e-32 STM1073 [S] COG1289 Predicted membrane protein Sty Salmonella ty... 135 2e-31 Z1311 [S] COG1289 Predicted membrane protein EcZ Escherichia col... 134 5e-31 VCA0718 [S] COG1289 Predicted membrane protein Vch Vibrio cholerae 134 7e-31 PM0392 [S] COG1289 Predicted membrane protein Pmu Pasteurella mu... 122 3e-27 NMB0050 [S] COG1289 Predicted membrane protein Nme Neisseria men... 117 5e-26 >RSc2889 [S] COG1289 Predicted membrane protein Rso Ralstonia solanacearum Length = 740 Score = 486 bits (1252), Expect = e-137, Method: Compositional matrix adjust. Identities = 247/493 (50%), Positives = 343/493 (69%), Gaps = 5/493 (1%) Query: 1 VLAEALFELARYLRIKAEFYDVRHDLAGQFNQLVRQQIVVADKQQASRDLILRDLYTKQD 60 VLAE L+ELA Y+ KA FYD D QF+ LVRQQI VADKQQ +RD + RD D Sbjct: 169 VLAECLYELAIYVERKAGFYDTALDFDAQFDALVRQQISVADKQQLARDFVFRDNRDNGD 228 Query: 61 ---GLLVQVHLSMLELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAAQDIESIAYA 117 G LVQ+H+ ML+LYE +LST+ DY LRQ DA++M LRD + D+E++AYA Sbjct: 229 TGDGRLVQIHMRMLDLYEYLLSTNTDYPLLRQWLADAEIMRLLRDSIERMRLDLEALAYA 288 Query: 118 ITRNKASEPTVNYKAELRAVQFEMHELAQPGPRQASEEALTILRVTYNKIRDIIELISQV 177 + R++ S + Y E+ A+ + EL Q G EA+ L + +R I L++Q+ Sbjct: 289 VGRDRPSPTPMPYDKEMAAIDAALDEL-QHGHHAIPLEAIAALEESVATVRGAIRLMAQL 347 Query: 178 HQATQNPVDPIPILPGSDMTPFLTQQKFKFNMLLVNLRWQSPIFRFAIRVALAVTTGLWI 237 H AT PV +L DMTPFLT+Q+++ ++L W+SP RFA+R A+AV GLWI Sbjct: 348 HAATATPVALSSVLLRPDMTPFLTRQQYELRLVLDAFNWRSPTLRFALRTAMAVAAGLWI 407 Query: 238 ANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITMLILRFVHNPLGQL 297 A+ LPY SHGYW++LTIV+ILKP FS T+QR DR++GT+IGC+I ++LR+VH+ L Sbjct: 408 ADHLPYASHGYWVLLTIVVILKPTFSMTRQRNVDRVLGTLIGCVIAAVLLRYVHSTWILL 467 Query: 298 AVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQGVIGERLIDTIIGVVIAT 357 VL+ ++ A+ AF ++YRYTA AA+VQ+L+ +NLL+P G +G IGERL+DT++G IAT Sbjct: 468 GVLYLSTAASAAFVTVRYRYTAAAAAVQVLIQINLLLP-GSKGAIGERLVDTLLGAAIAT 526 Query: 358 VFSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQDDFFYRVCRKGFMDSLAAL 417 FSYVLPAWEYR+LPKL+ +VL++++R++ ++RD+L G +DDF YRV RK FMD+L L Sbjct: 527 AFSYVLPAWEYRNLPKLVDDVLRTNRRFIESARDLLLGSPKDDFAYRVQRKQFMDALTGL 586 Query: 418 ISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLMLRRHQENLPQAQVSRLIEE 477 I+A RM++EP ++ RAV LNRFIVQNYLVAAH+AA+R+++R+ + L A LIE+ Sbjct: 587 IAAFARMLNEPKSRHRAVDNLNRFIVQNYLVAAHVAAVRILVRQRGQELDAADTHALIEQ 646 Query: 478 TYLEASQHLAEAQ 490 T A + LA A+ Sbjct: 647 TVESALESLARAK 659 >PA0454 [S] COG1289 Predicted membrane protein Pae Pseudomonas aeruginosa Length = 733 Score = 147 bits (370), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 144/499 (28%), Positives = 240/499 (48%), Gaps = 30/499 (6%) Query: 2 LAEALFELARYLRIKAEFYD-VRH-DLAGQFNQLVRQ--QIVVADKQQASRDLILRDLYT 57 L+ FEL YLRIK+ ++ +R D+ GQ L RQ ++VVA Q +++ IL L Sbjct: 178 LSRLYFELGEYLRIKSSLFEPLRQLDVEGQRLALARQNGKVVVALNQ--AKETILNRLGH 235 Query: 58 KQDGLLVQVHLSML----ELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAAQDIES 113 + G V +L + +++E+ S+H Y L + F +DV+ + L N+ + ++ Sbjct: 236 GRPGPKVSRYLKLYFIAQDVHERASSSHYPYNRLAEAFFHSDVLFRCQRLLNQQGKACQA 295 Query: 114 IAYAITRNKASEPTVNYKAELRAVQFEMHELAQPGPRQASEEALTILRVTYNKIRDIIEL 173 +A AI R + + + L +Q + L RQ S A L + + + Sbjct: 296 LARAI-RLRQPFDYADRELALEDLQASLEHL-----RQQSNPAWKGLLRSLGALAANLTT 349 Query: 174 ISQVHQATQNPVDPIPILPGS---DMTPFLTQQKFKFNMLLVNLRWQSPIFRFAIRVALA 230 + + NP D I S D +P K F L L S +FR +R+ALA Sbjct: 350 LDRKLAGASNP-DAIADEQDSALLDRSP--RSLKDAFERLRQQLTPTSLLFRHGLRMALA 406 Query: 231 VTTGLWIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITMLILRFV 290 +T G + + + + + GYWI+LT V + +PN+ AT+ R+ R++GTV+G + ++ Sbjct: 407 LTAGYGVLHWI-HPTQGYWILLTTVFVCQPNYGATRLRLVQRILGTVVGLVGGWALIDLF 465 Query: 291 HNPLGQLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQGVIGERLIDTI 350 +PL Q LFA + F RYT A++ +L+L G+I RL DT+ Sbjct: 466 PSPLVQ--SLFAVAAGVAFFATRSSRYTLATAAITLLVLFCFNQVGDGYGLILPRLFDTL 523 Query: 351 IGVVIATVFSY-VLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQDDFFYRVCRKG 409 +G +IA + + VLP W+ R L ++L N L + RYL +DD YR R+ Sbjct: 524 LGSLIAGLAVFLVLPDWQGRRLNRMLANTLACNSRYLRQIMQQYATGKRDDLDYRTARRN 583 Query: 410 FMDSLAALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLMLRRHQENLPQA 469 ++ AAL + L M+ EP ++ RF+V ++ + ++++ L H+E+LP+ Sbjct: 584 AHNADAALSTTLSNMLLEPGHFRKDAEIGFRFLVLSHTLLSYLSG----LGAHRESLPED 639 Query: 470 QVSRLIEETYLEASQHLAE 488 L+E S L E Sbjct: 640 ASDGLLERAAERLSASLEE 658 >ECs1044 [S] COG1289 Predicted membrane protein Ecs Escherichia coli O157:H7 Length = 720 Score = 138 bits (347), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 126/497 (25%), Positives = 233/497 (46%), Gaps = 28/497 (5%) Query: 2 LAEALFELARYLRIKAEFYDVRHDLAGQ---FNQLVRQQIVVADKQQASRDLILRDLYTK 58 LA +LARYL +K+ +D + Q ++ + +++A Q L+ R + Sbjct: 173 LARCYEQLARYLELKSRMFDPDIEDESQAPLYDLALANGLLMATLNQTKLSLLTRLRGDR 232 Query: 59 -QDGLLVQVHLSML--ELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAAQDIESIA 115 Q G +H + +++E+ S+H Y LR+HF +DV+ + L + Q + ++ Sbjct: 233 GQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFRFQRLMSMQGQACQQLS 292 Query: 116 YAITRNKASEPTVNYKAELRAVQFEMHELAQPGPRQASEEALTILRVTYNKIRDIIELIS 175 I + + +++ + + + G A + L L N +R I ++ Sbjct: 293 RCILLRQPYQHDPHFERAFTHIDAALERMRDNG---APADLLKTLGFLLNNLRAIDAQLA 349 Query: 176 QVH--QATQNPVDPIPILPGSDMTPFLTQQKFKFNMLLVNLRWQSPIFRFAIRVALAVTT 233 + QA P + D L+ + + +S +FR A+R++L + Sbjct: 350 TIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTP---ESALFRHAVRMSLVLCF 406 Query: 234 GLWIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITMLILRFVHNP 293 G I Q+ M HGYWI+LT + + +PN++AT+ R+ R+IGT++G I + +L FV + Sbjct: 407 GYAII-QITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLVGIAIGIPVLWFVPSL 465 Query: 294 LGQLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQG--VIGERLIDTII 351 GQL +L V AF ++Y + A++ I +L+ L +G V R+IDT+I Sbjct: 466 EGQLVLLVITGVLFFAFRNVQYAH----ATMFITLLVLLCFNLLGEGFEVALPRVIDTLI 521 Query: 352 GVVIA-TVFSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQDDFFYRVCRKGF 410 G IA SY+ P W++R+LP++L +++ RYL A + + YR+ R+ Sbjct: 522 GCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAILEQYHQGRDNRLAYRIARRDA 581 Query: 411 MDSLAALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLMLRRHQENLPQAQ 470 + A L S + M EP + R + N+ ++I+A L H+E L + Sbjct: 582 HNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYISA----LGAHREQLTNPE 637 Query: 471 VSRLIEE--TYLEASQH 485 + +++ Y++ + H Sbjct: 638 ILAFLDDAVCYVDDALH 654 >yccS [S] COG1289 Predicted membrane protein Eco Escherichia coli K12 Length = 720 Score = 137 bits (346), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 126/497 (25%), Positives = 233/497 (46%), Gaps = 28/497 (5%) Query: 2 LAEALFELARYLRIKAEFYDVRHDLAGQ---FNQLVRQQIVVADKQQASRDLILRDLYTK 58 LA +LARYL +K+ +D + Q ++ + +++A Q L+ R + Sbjct: 173 LARCYEQLARYLELKSRMFDPDIEDQSQAPLYDLALANGLLMATLNQTKLSLLTRLRGDR 232 Query: 59 -QDGLLVQVHLSML--ELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAAQDIESIA 115 Q G +H + +++E+ S+H Y LR+HF +DV+ + L + Q + ++ Sbjct: 233 GQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFRFQRLMSMQGQACQQLS 292 Query: 116 YAITRNKASEPTVNYKAELRAVQFEMHELAQPGPRQASEEALTILRVTYNKIRDIIELIS 175 I + + +++ + + + G A + L L N +R I ++ Sbjct: 293 RCILLRQPYQHDPHFERAFTHIDAALERMRDNG---APADLLKTLGFLLNNLRAIDAQLA 349 Query: 176 QVH--QATQNPVDPIPILPGSDMTPFLTQQKFKFNMLLVNLRWQSPIFRFAIRVALAVTT 233 + QA P + D L+ + + +S +FR A+R++L + Sbjct: 350 TIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTP---ESALFRHAVRMSLVLCF 406 Query: 234 GLWIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITMLILRFVHNP 293 G I Q+ M HGYWI+LT + + +PN++AT+ R+ R+IGT++G I + +L FV + Sbjct: 407 GYAII-QITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLVGIAIGIPVLWFVPSL 465 Query: 294 LGQLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQG--VIGERLIDTII 351 GQL +L V AF ++Y + A++ I +L+ L +G V R+IDT+I Sbjct: 466 EGQLVLLVITGVLFFAFRNVQYAH----ATMFITLLVLLCFNLLGEGFEVALPRVIDTLI 521 Query: 352 GVVIA-TVFSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQDDFFYRVCRKGF 410 G IA SY+ P W++R+LP++L +++ RYL A + + YR+ R+ Sbjct: 522 GCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAILEQYHQGRDNRLAYRIARRDA 581 Query: 411 MDSLAALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLMLRRHQENLPQAQ 470 + A L S + M EP + R + N+ ++I+A L H+E L + Sbjct: 582 HNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYISA----LGAHREQLTNPE 637 Query: 471 VSRLIEE--TYLEASQH 485 + +++ Y++ + H Sbjct: 638 ILAFLDDAVCYVDDALH 654 >YPO1438 [S] COG1289 Predicted membrane protein Ype Yersinia pestis Length = 712 Score = 137 bits (345), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 133/498 (26%), Positives = 234/498 (46%), Gaps = 34/498 (6%) Query: 2 LAEALFELARYLRIKAEFYDVRHDLAGQFNQ-----LVRQQIVVADKQQASRDLILRDLY 56 LA +LA YL KA +D D+ NQ + +VA QA L+ R Sbjct: 172 LARCYQQLAHYLEAKANLFDP--DIESDINQPLIDVAMVNSTLVATLNQAKASLVTRLKG 229 Query: 57 TK-QDGLLVQVHLSML--ELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAAQDIES 113 + Q G +H + +++E+ S+H Y LR+ F +DV+ + L + A+ Sbjct: 230 DRGQRGTRRTLHYYFVAQDIHERASSSHFQYQVLREKFRYSDVLFRFQRLLSMQAKACNH 289 Query: 114 IAYAITRNKASEPTVNYKAELRAVQFEMHELAQPG-PRQASEEALTILRVTYNKIRDIIE 172 ++ +I ++ + ++ RA F LA+ + + + L +R I Sbjct: 290 LSQSILMHQKYQHDPRFE---RAFTFLDAALAREELAHHENTQQVKALSYLLKNLRAIDA 346 Query: 173 LISQVHQATQNPVDPIPILPGSD--MTPFLTQQKFKFNMLLVNLRWQSPIFRFAIRVALA 230 ++ + DP P SD +T + + K + + +L QS +FR AIR+++ Sbjct: 347 QLAGIESEQVLAQDPTPDNHLSDDRITGW-SDIKLRISR---HLTPQSALFRHAIRMSIV 402 Query: 231 VTTGLWIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITMLILRFV 290 + G + Q + HGYWI+LT + + +PN+SAT++R+A R+IGT+ G L+ + IL FV Sbjct: 403 LCVG-YAFIQFTGLRHGYWILLTSLFVCQPNYSATRRRLALRIIGTLAGILVGLPILYFV 461 Query: 291 HNPLGQLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQG--VIGERLID 348 + GQL ++ + V AF ++Y + A++ I +L+ L +G V R+ D Sbjct: 462 PSIEGQLTLIVISGVLFFAFRNVQYAH----ATMFITLLVLLCFNLLGEGFEVAAPRVFD 517 Query: 349 TIIGVVIATV-FSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQDDFFYRVCR 407 T++G IA V S++ P W++R LP ++ ++ RYL A + YRV R Sbjct: 518 TLLGCAIAWVAVSFIWPDWKFRQLPTVVHKTFNANCRYLDAILAQYHQGKDNSLLYRVAR 577 Query: 408 KGFMDSLAALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLMLRRHQENLP 467 + + A L S + M EP + R + N+ + ++I+A L H+E L Sbjct: 578 RDAHNCDAELASVISNMSAEPKNDKETQEAAFRLLCLNHTMLSYISA----LGAHREKLT 633 Query: 468 QAQVSRLIEE--TYLEAS 483 + L+ + Y+E + Sbjct: 634 NSTTLNLLNDAICYIEGT 651 >STM1073 [S] COG1289 Predicted membrane protein Sty Salmonella typhimurium LT2 Length = 717 Score = 135 bits (341), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 133/509 (26%), Positives = 225/509 (44%), Gaps = 52/509 (10%) Query: 2 LAEALFELARYLRIKAEFYDVR---------HDLA---GQFNQLVRQQIVV------ADK 43 LA + +LA YL +K+ +D +DLA GQ + Q V D+ Sbjct: 170 LARSYEQLAHYLELKSRLFDPDIEDESQAPLYDLALANGQLMATLNQTKVSLLTRLRGDR 229 Query: 44 QQASRDLILRDLYTKQDGLLVQVHLSMLELYEQVLSTHADYAFLRQHFGDADVMVFLRDL 103 Q L + QD ++E+ S+H Y LR +F +DVM + L Sbjct: 230 GQRGTRRTLHYYFVAQD------------IHERASSSHIQYQTLRDYFRHSDVMFRFQRL 277 Query: 104 ANKAAQDIESIAYAITRNKASEPTVNYKAELRAVQFEMHELAQPGPRQASEEALTILRVT 163 + AQ +A I + ++ + + + G AS E L L Sbjct: 278 MSMQAQACTQLARCILLRTPYQHDPRFERVFTHIDAALERMRASG---ASLELLNTLGFL 334 Query: 164 YNKIRDIIELISQVH--QATQNPVDPIPILPGSDMTPFLTQQKFKFNMLLVNLRWQSPIF 221 +R I ++ + QA P + D + + + N +S +F Sbjct: 335 LTNLRAIDAQLATIESEQAQAMPRNESENQLADDSLHGFSDIWLRLSR---NFTPESALF 391 Query: 222 RFAIRVALAVTTGLWIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCL 281 R A+R++L + G + Q+ M HGYWI+LT + + +PN++AT+ R+A R+IGT++G Sbjct: 392 RHAVRMSLVLCIG-YALIQITGMRHGYWILLTSLFVCQPNYNATRHRLALRIIGTLVGVA 450 Query: 282 ITMLILRFVHNPLGQLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQG- 340 I + IL FV + GQL +L V AF ++Y + A++ I +L+ L +G Sbjct: 451 IGLPILWFVPSLEGQLVLLVITGVLFFAFRNVQYAH----ATMFITLLVLLCFNLLGEGF 506 Query: 341 -VIGERLIDTIIGVVIA-TVFSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQ 398 V R++DT+IG IA S++ P W +R+LP++L+ ++ RYL A + Sbjct: 507 EVALPRVVDTLIGCAIAWAAVSFIWPDWRFRNLPRVLQRATDANCRYLDAILEQYHQGRD 566 Query: 399 DDFFYRVCRKGFMDSLAALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLM 458 + YR+ R+ + A L S + M EP R + N+ ++I+A Sbjct: 567 NRLAYRIARRDAHNRDAELASVVSNMSSEPDVTAETREAAFRLLCLNHTFTSYISA---- 622 Query: 459 LRRHQENLPQAQVSRLIEE--TYLEASQH 485 L H+E L V L+++ Y++ + H Sbjct: 623 LGAHREKLSNPDVLGLLDDAVCYVDDALH 651 >Z1311 [S] COG1289 Predicted membrane protein EcZ Escherichia coli O157:H7 EDL933 Length = 720 Score = 134 bits (338), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 125/497 (25%), Positives = 232/497 (46%), Gaps = 28/497 (5%) Query: 2 LAEALFELARYLRIKAEFYDVRHDLAGQ---FNQLVRQQIVVADKQQASRDLILRDLYTK 58 LA +LARYL +K+ +D + Q ++ + +++A Q L+ R + Sbjct: 173 LARCYEQLARYLELKSRMFDPDIEDESQAPLYDLALANGLLMATLNQTKLSLLTRLRGDR 232 Query: 59 -QDGLLVQVHLSML--ELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAAQDIESIA 115 Q G +H + +++E+ S+H Y LR+HF +DV+ + L + Q + ++ Sbjct: 233 GQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFRFQRLMSMQGQACQQLS 292 Query: 116 YAITRNKASEPTVNYKAELRAVQFEMHELAQPGPRQASEEALTILRVTYNKIRDIIELIS 175 I + + +++ + + + G A + L L N +R I ++ Sbjct: 293 RCILLRQPYQHDPHFERAFTHIDAALERMRDNG---APADLLKTLGFLLNNLRAIDAQLA 349 Query: 176 QVH--QATQNPVDPIPILPGSDMTPFLTQQKFKFNMLLVNLRWQSPIFRFAIRVALAVTT 233 + QA P + D L+ + + +S +FR A+R++L + Sbjct: 350 TIESEQAQALPHNNDXNELADDSPHGLSDIWLRLSRHFTP---ESALFRHAVRMSLVLCF 406 Query: 234 GLWIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITMLILRFVHNP 293 G I Q+ M HGYWI+LT + + +PN++AT+ R+ R+IGT++G I + +L V + Sbjct: 407 GYAII-QITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLVGIAIGIPVLWXVPSL 465 Query: 294 LGQLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQG--VIGERLIDTII 351 GQL +L V AF ++Y + A++ I +L+ L +G V R+IDT+I Sbjct: 466 EGQLVLLVITGVLFFAFRNVQYAH----ATMFITLLVLLCFNLLGEGFEVALPRVIDTLI 521 Query: 352 GVVIA-TVFSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQDDFFYRVCRKGF 410 G IA SY+ P W++R+LP++L +++ RYL A + + YR+ R+ Sbjct: 522 GCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAILEQYHQGRDNRLAYRIARRDA 581 Query: 411 MDSLAALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLMLRRHQENLPQAQ 470 + A L S + M EP + R + N+ ++I+A L H+E L + Sbjct: 582 HNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYISA----LGAHREQLTNPE 637 Query: 471 VSRLIEE--TYLEASQH 485 + +++ Y++ + H Sbjct: 638 ILAFLDDAVCYVDDALH 654 >VCA0718 [S] COG1289 Predicted membrane protein Vch Vibrio cholerae Length = 725 Score = 134 bits (336), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 124/492 (25%), Positives = 221/492 (44%), Gaps = 20/492 (4%) Query: 2 LAEALFELARYLRIKAEFYDVRHDLAGQFNQLVRQQI---VVADKQQASRDLILRDLYTK 58 LA +LA YL K+ + ++ Q ++++ + V Q + R Sbjct: 175 LANVFLQLANYLEAKSTLFHPVSNMIPQPHRIIEANLNAATVNALNQCKAVFLTRSKRGH 234 Query: 59 QDGL---LVQVHLSMLELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAAQDIESIA 115 D + ++ +++E+V S+H Y L HFG +D++ + L A+ IA Sbjct: 235 VDSASDRFLNIYFLAQDIHERVSSSHYRYQELADHFGRSDILFRFKYLLETQAKACRDIA 294 Query: 116 YAITRNKASEPTVNYKAELRAVQFEMHELAQPGPRQASEEALTILRVTYNKIRDIIELIS 175 +I + + L +Q + L Q R+ + L L +N + + + ++ Sbjct: 295 QSIRLGHSYQHDSASIVALDELQLSLSYLRQQ-ERRDWKSLLGQLGYLFNNLATVEKQLN 353 Query: 176 QVHQATQNPVDPIPILPGSDMTPFLTQQKFKFNMLLVNLRWQSPIFRFAIRVALAVTTGL 235 V NP P D T T + + NL S +FR A+R+++ +T G Sbjct: 354 NV----SNPDVAKPEEGVLDDTEAHTLGSM-WQRIRANLNKDSLLFRHALRLSITLTLGY 408 Query: 236 WIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITMLILRFVHNPLG 295 I + GYWI+LT + + +PN++ATKQ++ R+IGT+ G LI + +L F + Sbjct: 409 AIIQGFG-IERGYWILLTTLFVCQPNYAATKQKLTARIIGTLAGLLIGVPLLTFFPSQES 467 Query: 296 QLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQGVIGERLIDTIIGVVI 355 QL + + V AF Y Y ++ +L N L V+ RL DT+IG + Sbjct: 468 QLVFIVFSGVMFFAFRLNNYGYATGFITLLVLFCFNQLGEG--YAVVLPRLADTLIGCAL 525 Query: 356 AT-VFSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQDDFFYRVCRKGFMDSL 414 A +LP W+ + L K++ + ++++YL +D YR+ R+ + Sbjct: 526 AVAAVVLILPDWQSKRLHKVMAEAIDANKQYLAQIIGQYRIGKKDSLSYRIARRHAHNQD 585 Query: 415 AALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLMLRRHQENLPQAQVSRL 474 AAL +A+ M+ EP + A E RF+ N+ + ++I+A L H+ L V +L Sbjct: 586 AALSAAVTNMLAEPGRYRAAADESFRFLTLNHALLSYISA----LGAHRTRLDDETVHQL 641 Query: 475 IEETYLEASQHL 486 + +++ QHL Sbjct: 642 VLDSHRVIHQHL 653 >PM0392 [S] COG1289 Predicted membrane protein Pmu Pasteurella multocida Length = 717 Score = 122 bits (305), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 116/471 (24%), Positives = 217/471 (46%), Gaps = 34/471 (7%) Query: 2 LAEALFELARYLRIKAEFYDVRHDLAGQFNQLVRQQIVVADKQQA---SRDLILRDLYTK 58 +A++ L YL K++F+D + QL +++ +A K A + + L+ + Sbjct: 164 IAKSFLALGHYLDAKSQFFD-----PDEIEQLANKEVNLAMKDSALIEAFNATRIALFYR 218 Query: 59 QDG--------LLVQVHLSMLELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAAQD 110 G +++ + + +++E+ S+ +Y + + + D++ ++ L AQ Sbjct: 219 IRGQNRHSRTQKMIRYYFAAQDIHERANSSLFNYHTMAEQLKNTDLIFRIQRLFELQAQA 278 Query: 111 IESIAYAITRNKASEPTVNYKAELRAV----QFEMHELAQPGPRQASEEALTILRVTYNK 166 I ++ +NK E N K E V FE++ Q T++ Sbjct: 279 CREIGLSLQQNK--EYHYNNKVEKAIVGLNQSFELYAKTHLENEQVVLNLKTLIENLQAV 336 Query: 167 IRDIIELISQVHQATQNPVDPIPILPGSDMTPFLTQQKFKFNMLLVNLRWQSPIFRFAIR 226 + L + HQA + I + L K + + S +FR A+R Sbjct: 337 EWQLSHLDQETHQAERASTAKIHTEQVRGLRNILYAMK-------SHCHFNSQLFRHAVR 389 Query: 227 VALAVTTGLWIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITMLI 286 +++ V T I + + GYWI+LT V + +PN+SATK R+ R+IGT++G +I L Sbjct: 390 LSIVVFTACSIV-EFFQLERGYWILLTSVFVCQPNYSATKLRLRQRIIGTILGVIIGSL- 447 Query: 287 LRFVHNPLG-QLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQGVIGER 345 L +++ L QL ++ A S F Y ++ ++Q+L+ +++ H+ + R Sbjct: 448 LPYINPTLELQLGLIVATSTLFFFFRTNNYSFSTFFITLQVLISFDVMGFDIHEAMYS-R 506 Query: 346 LIDTIIGVVIA-TVFSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLEGKVQDDFFYR 404 +IDT IG IA SY+ P W Y L K+ R +KS+ +YL L+ D+ YR Sbjct: 507 VIDTFIGAFIAWFAVSYLWPDWRYLQLDKVSRQAVKSNAKYLLYVISQLQFGKGDNLKYR 566 Query: 405 VCRKGFMDSLAALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAAL 455 + R+ ++ AL + + M +EP Q +++ + NY + ++I+AL Sbjct: 567 IVRRHAHENATALSTTISNMNNEPNKYQAHLQKGFELLKINYSLLSYISAL 617 >NMB0050 [S] COG1289 Predicted membrane protein Nme Neisseria meningitidis MC58 Length = 716 Score = 117 bits (294), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 134/512 (26%), Positives = 225/512 (43%), Gaps = 43/512 (8%) Query: 2 LAEALFELARYLRIKAEFYD--------VRH-DLAGQFNQLVRQQIVVADKQQASRDLIL 52 +A A L YL KA+F+D RH DLA + ++ A Q R + Sbjct: 165 VANAYDALGGYLEAKADFFDPDEAAWIGNRHIDLA-----MSNTGVITAFNQ--CRSALF 217 Query: 53 RDLYTKQ----DGLLVQVHLSMLELYEQVLSTHADYAFLRQHFGDADVMVFLRDLANKAA 108 L K +++ + + +++E++ S H DY + + F + D++ + L Sbjct: 218 YRLRGKHRHPRTAKMLRYYFAAQDIHERISSAHVDYQEMSEKFKNTDIIFRIHRLLEMQG 277 Query: 109 QDIESIAYAITRNKASEPTVNYKAELRAVQFEMHELAQPGPRQASEEALTILRVTYNKIR 168 Q + A A+ +AS+ V K RA++ L S + + LR + + Sbjct: 278 QACRNTAQAL---RASKDYVYSKRLGRAIEGCRQSLRLLSDSNDSPD-IRHLRRLLDNLG 333 Query: 169 DIIELISQV-HQATQNPVDPIPILPGSDMTPFLTQQKFK--FNMLLVNLRWQSPIFRFAI 225 + + Q+ H Q D + G L K + + L +S +FR A+ Sbjct: 334 SVDQQFRQLQHNGLQAENDRM----GDTRIAALETSSLKNTWQAIRPQLNLESGVFRHAV 389 Query: 226 RVALAVTTGLWIANQLPYMSHGYWIVLTIVIILKPNFSATKQRMADRLIGTVIGCLITML 285 R++L V I L ++ GYWI+LT + + +PN++ATK R+ R+ GTV+G ++ L Sbjct: 390 RLSLVVAAACTIVEALN-LNLGYWILLTALFVCQPNYTATKSRVRQRIAGTVLGVIVGSL 448 Query: 286 ILRFVHNPLGQLAVLFAASVAAPAFTYIKYRYTAIAASVQILMLLNLLVPAGHQ--GVIG 343 + F + +L ++ A++ KY ++ ++Q L L+L AG + Sbjct: 449 VPYFTPSVETKLWIVIASTTLFFMTRTYKYSFSTFFITIQALTSLSL---AGLDVYAAMP 505 Query: 344 ERLIDTIIGVVIA-TVFSYVLPAWEYRDLPKLLRNVLKSSQRYLTASRDMLE-GKVQDDF 401 R+IDTIIG +A SY+ P W+Y L + + S+ YL + L+ G+ DD Sbjct: 506 VRIIDTIIGASLAWAAVSYLWPDWKYLTLERTAALAVCSNGAYLEKITERLKSGETGDDV 565 Query: 402 FYRVCRKGFMDSLAALISALVRMMDEPATKQRAVRELNRFIVQNYLVAAHIAALRLMLRR 461 YR R+ + AAL S L M EPA +++ + Y + +I+AL Sbjct: 566 EYRATRRRAHEHTAALSSTLSDMSSEPAKFADSLQPGFTLLKTGYALTGYISALGAYRSE 625 Query: 462 -HQENLPQ--AQVSRLIEETYLEASQHLAEAQ 490 H+E P AQ E T QHL E + Sbjct: 626 MHEECSPDFTAQFHLAAEHT-AHIFQHLPETE 656