BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0097.p (305 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1320 [J] COG0223 Methionyl-tRNA formyltransferase Rso Ralston... 367 e-101 PA3554_1 [J] COG0223 Methionyl-tRNA formyltransferase Pae Pseudo... 243 3e-64 STM2299_1 [J] COG0223 Methionyl-tRNA formyltransferase Sty Salmo... 234 1e-61 YPO2420_1 [J] COG0223 Methionyl-tRNA formyltransferase Ype Yersi... 228 1e-59 yfbG_1 [J] COG0223 Methionyl-tRNA formyltransferase Eco Escheric... 228 2e-59 ECs3143_1 [J] COG0223 Methionyl-tRNA formyltransferase Ecs Esche... 227 3e-59 Z3513_1 [J] COG0223 Methionyl-tRNA formyltransferase EcZ Escheri... 227 3e-59 SPy1628 [J] COG0223 Methionyl-tRNA formyltransferase Spy Strepto... 122 9e-28 SA1059 [J] COG0223 Methionyl-tRNA formyltransferase Sau Staphylo... 120 3e-27 BH2508 [J] COG0223 Methionyl-tRNA formyltransferase Bha Bacillus... 117 2e-26 >RSc1320 [J] COG0223 Methionyl-tRNA formyltransferase Rso Ralstonia solanacearum Length = 311 Score = 367 bits (942), Expect = e-101, Method: Compositional matrix adjust. Identities = 180/282 (63%), Positives = 206/282 (73%), Gaps = 6/282 (2%) Query: 3 AVVFAYHDVGVRCLKVLLARGVQVSLVVTHEDSATENIWFGSVAGVCREHGIACITPADP 62 AVVFAYH+VGVRCL+VL ARG+Q+ LVVTHEDSATENIWFGSV +E GI +TP D Sbjct: 5 AVVFAYHNVGVRCLRVLAARGIQIELVVTHEDSATENIWFGSVRATAQELGIPFVTPEDA 64 Query: 63 KSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPINWAVL 122 + L A++ A PDFIFSFYYRHM+PV +L A+ GA+NMHGSLLPKYRGRVP NWAVL Sbjct: 65 RGEDLFARIAAIAPDFIFSFYYRHMIPVRLLGLARHGAFNMHGSLLPKYRGRVPTNWAVL 124 Query: 123 HGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGKVVVAAELTLWNVLPAMLS 182 HGETE+GATLHEM KPDAG IV QT VPILPDDTAHEVF K VAAE TLW VLP M++ Sbjct: 125 HGETESGATLHEMVEKPDAGYIVDQTIVPILPDDTAHEVFEKTTVAAEQTLWRVLPDMIA 184 Query: 183 GRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAVAPPYPGAFEEIADDKITV 242 GR P PN L GSY+GGRKPEDGRIDW R A++V+NLVRAVAPPYPGAF + ++ V Sbjct: 185 GRIPQRPNRLEDGSYFGGRKPEDGRIDWSRPAQQVYNLVRAVAPPYPGAFTDAGGERYIV 244 Query: 243 TRTRLVPPSAHPALQRAHGMQDKFFEGGKLYARCGDGNFLQI 284 R RL S H + + F CGDG + I Sbjct: 245 ARARLARQSFSNLPPGLHVVDNAMF------GVCGDGGAIAI 280 >PA3554_1 [J] COG0223 Methionyl-tRNA formyltransferase Pae Pseudomonas aeruginosa Length = 310 Score = 243 bits (621), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 118/247 (47%), Positives = 162/247 (65%) Query: 2 NAVVFAYHDVGVRCLKVLLARGVQVSLVVTHEDSATENIWFGSVAGVCREHGIACITPAD 61 AVVFAYHD+G ++ LL G +++ V TH D EN ++ SVA +C E GI P D Sbjct: 4 KAVVFAYHDIGCTGIEALLNAGYEIAAVFTHADDPRENTFYASVARLCAERGIPLHAPED 63 Query: 62 PKSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPINWAV 121 P L +++ +PDF+FSFYYR +L E+LA A RGAYN+HGSLLP+YRGR P NW + Sbjct: 64 VNHPLWLERIRQLRPDFLFSFYYRRLLGAELLACAARGAYNLHGSLLPRYRGRAPANWVL 123 Query: 122 LHGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGKVVVAAELTLWNVLPAML 181 ++GET+TG TLH M + DAG I+AQ +V I P+DTA + GK+ AA L + LP + Sbjct: 124 VNGETQTGVTLHRMIERADAGPILAQQAVAIDPEDTALSLHGKLRKAAGALLRDSLPLLA 183 Query: 182 SGRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAVAPPYPGAFEEIADDKIT 241 G P + D S+ S++G R P DG +DW R AR++++LVRAV PYPGAF ++ + K+ Sbjct: 184 LGVLPEVEQDESQASHFGRRTPADGLLDWHRPARQLYDLVRAVTQPYPGAFCQVGEQKLI 243 Query: 242 VTRTRLV 248 V +V Sbjct: 244 VWSAEVV 250 >STM2299_1 [J] COG0223 Methionyl-tRNA formyltransferase Sty Salmonella typhimurium LT2 Length = 307 Score = 234 bits (598), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 115/249 (46%), Positives = 155/249 (62%) Query: 1 MNAVVFAYHDVGVRCLKVLLARGVQVSLVVTHEDSATENIWFGSVAGVCREHGIACITPA 60 M AV+FAYHD+G + ++ +L G +++ + TH D+ EN +FGSV+ E GI P Sbjct: 1 MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRQAAELGIPVYAPD 60 Query: 61 DPKSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPINWA 120 + P + ++ PD IFSFYYR++L E+L A GA+N+HGSLLP YRGR P+NW Sbjct: 61 NVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWV 120 Query: 121 VLHGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGKVVVAAELTLWNVLPAM 180 +++GE+ETG TLH M + DAG IVA V I DD A + K+ AA L ++LP M Sbjct: 121 LVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTM 180 Query: 181 LSGRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAVAPPYPGAFEEIADDKI 240 G PS+P S +YYG R+PEDG IDW + VHNLVRAVA P+PGAF K Sbjct: 181 KCGDIPSVPQRESDSTYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKF 240 Query: 241 TVTRTRLVP 249 T+ +R+ P Sbjct: 241 TIWSSRMCP 249 >YPO2420_1 [J] COG0223 Methionyl-tRNA formyltransferase Ype Yersinia pestis Length = 304 Score = 228 bits (581), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 114/246 (46%), Positives = 151/246 (61%) Query: 1 MNAVVFAYHDVGVRCLKVLLARGVQVSLVVTHEDSATENIWFGSVAGVCREHGIACITPA 60 M A+VFAYHD+G L L G + V TH D+ EN +F SVA V + + P Sbjct: 1 MKAIVFAYHDIGCVGLNALAEAGYDIQAVFTHTDNPGENRFFSSVARVAADLALPVFAPE 60 Query: 61 DPKSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPINWA 120 D P + +++ QPD IFSFYYR+ML E+L+ A +G +N+HGSLLP+YRGR PINW Sbjct: 61 DVNHPLWVERIRELQPDIIFSFYYRNMLSDEILSLAPQGGFNLHGSLLPQYRGRAPINWV 120 Query: 121 VLHGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGKVVVAAELTLWNVLPAM 180 +++GETETG TLH+M K DAG I Q V I DTA + K+ AA+ L N+LP M Sbjct: 121 LVNGETETGVTLHQMVKKADAGPIAGQYKVAISDVDTALTLHAKMRDAAQELLRNLLPRM 180 Query: 181 LSGRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAVAPPYPGAFEEIADDKI 240 G P P + SY+G R DG I W+++A ++NLVRAV PYPGAF + K+ Sbjct: 181 KEGPLPLTPQKEADASYFGRRTAADGEIHWQKSAFTINNLVRAVTEPYPGAFSYLGQRKL 240 Query: 241 TVTRTR 246 T+ R+R Sbjct: 241 TIWRSR 246 >yfbG_1 [J] COG0223 Methionyl-tRNA formyltransferase Eco Escherichia coli K12 Length = 305 Score = 228 bits (580), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 122/291 (41%), Positives = 169/291 (58%), Gaps = 8/291 (2%) Query: 1 MNAVVFAYHDVGVRCLKVLLARGVQVSLVVTHEDSATENIWFGSVAGVCREHGIACITPA 60 M VVFAYHD+G ++ LLA G ++S + TH D+ E ++GSVA + E GI P Sbjct: 1 MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPD 60 Query: 61 DPKSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPINWA 120 + P + ++ PD IFSFYYRH++ E+L A GA+N+HGSLLPKYRGR P+NW Sbjct: 61 NVNHPLWVERIAQLSPDVIFSFYYRHLIYDEILQLAPAGAFNLHGSLLPKYRGRAPLNWV 120 Query: 121 VLHGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGKVVVAAELTLWNVLPAM 180 +++GETETG TLH M + DAGAIVAQ + I PDD A + K+ AA L LPA+ Sbjct: 121 LVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCHAARQLLEQTLPAI 180 Query: 181 LSGRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAVAPPYPGAFEEIADDKI 240 G + ++ + +G R P+D ++W + A +HN+VRAVA P+PGAF + + K Sbjct: 181 KHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKF 240 Query: 241 TVTRTRLVPPSAHPALQRAHGMQDKFFEGGKLYARCGDGNFLQILGIQIND 291 TV +R+ HP +A L CGDG L+I+ Q D Sbjct: 241 TVWSSRV-----HPHASKAQ--PGSVISVAPLLIACGDGA-LEIVTGQAGD 283 >ECs3143_1 [J] COG0223 Methionyl-tRNA formyltransferase Ecs Escherichia coli O157:H7 Length = 305 Score = 227 bits (578), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 122/291 (41%), Positives = 169/291 (58%), Gaps = 8/291 (2%) Query: 1 MNAVVFAYHDVGVRCLKVLLARGVQVSLVVTHEDSATENIWFGSVAGVCREHGIACITPA 60 M VVFAYHD+G ++ LLA G ++S + TH D+ E ++GSVA + E GI P Sbjct: 1 MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPD 60 Query: 61 DPKSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPINWA 120 + P + ++ P+ IFSFYYRH++ E+L A GA+N+HGSLLPKYRGR P+NW Sbjct: 61 NVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPAGAFNLHGSLLPKYRGRAPLNWV 120 Query: 121 VLHGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGKVVVAAELTLWNVLPAM 180 +++GETETG TLH M + DAGAIVAQ V I PDD A + K+ AA L LPA+ Sbjct: 121 LVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAI 180 Query: 181 LSGRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAVAPPYPGAFEEIADDKI 240 G + ++ + +G R P+D ++W + A +HN+VRAVA P+PGAF + + K Sbjct: 181 KHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKF 240 Query: 241 TVTRTRLVPPSAHPALQRAHGMQDKFFEGGKLYARCGDGNFLQILGIQIND 291 TV +R+ HP +A L CGDG L+I+ Q D Sbjct: 241 TVWSSRV-----HPHASKAQ--PGSVISVAPLLIACGDGA-LEIVTGQAGD 283 >Z3513_1 [J] COG0223 Methionyl-tRNA formyltransferase EcZ Escherichia coli O157:H7 EDL933 Length = 305 Score = 227 bits (578), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 122/291 (41%), Positives = 169/291 (58%), Gaps = 8/291 (2%) Query: 1 MNAVVFAYHDVGVRCLKVLLARGVQVSLVVTHEDSATENIWFGSVAGVCREHGIACITPA 60 M VVFAYHD+G ++ LLA G ++S + TH D+ E ++GSVA + E GI P Sbjct: 1 MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPD 60 Query: 61 DPKSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPINWA 120 + P + ++ P+ IFSFYYRH++ E+L A GA+N+HGSLLPKYRGR P+NW Sbjct: 61 NVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPAGAFNLHGSLLPKYRGRAPLNWV 120 Query: 121 VLHGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGKVVVAAELTLWNVLPAM 180 +++GETETG TLH M + DAGAIVAQ V I PDD A + K+ AA L LPA+ Sbjct: 121 LVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAI 180 Query: 181 LSGRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAVAPPYPGAFEEIADDKI 240 G + ++ + +G R P+D ++W + A +HN+VRAVA P+PGAF + + K Sbjct: 181 KHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKF 240 Query: 241 TVTRTRLVPPSAHPALQRAHGMQDKFFEGGKLYARCGDGNFLQILGIQIND 291 TV +R+ HP +A L CGDG L+I+ Q D Sbjct: 241 TVWSSRV-----HPHASKAQ--PGSVISVAPLLIACGDGA-LEIVTGQAGD 283 >SPy1628 [J] COG0223 Methionyl-tRNA formyltransferase Spy Streptococcus pyogenes M1 GAS Length = 311 Score = 122 bits (306), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 74/230 (32%), Positives = 115/230 (50%), Gaps = 5/230 (2%) Query: 29 VVTHEDSAT---ENIWFGSVAGVCREHGIACITPADPKSPQLLAQVQAAQPDFIFSFYYR 85 VVT D A ++I V + EHGI+ P Q L ++ D I + + Sbjct: 31 VVTQPDRAVGRKKDIKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFG 90 Query: 86 HMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPINWAVLHGETETGATLHEMTVKPDAGAIV 145 LP +L + A N+H SLLPKYRG PI++A+++G+ E G T+ EM + DAG +V Sbjct: 91 QFLPT-ILLDSVSFAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMV 149 Query: 146 AQTSVPILPDDTAHEVFGKVVVAAELTLWNVLPAMLSGRTPSMPNDLSKGSYYGGRKPED 205 A+ S PIL D +F K+ + L + LPA LSG +P D S+ ++ PE Sbjct: 150 AKASTPILETDNVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEH 209 Query: 206 GRIDWRRTAREVHNLVRAVAPPYPGAFEEIADDKITVTRTRLVPPSAHPA 255 ++DW + +EV N +R + P+P A + ++ + +L P Sbjct: 210 EKLDWTMSNQEVFNHIRGMN-PWPVAHTFLEGQRLKIYEAQLAEGEGLPG 258 >SA1059 [J] COG0223 Methionyl-tRNA formyltransferase Sau Staphylococcus aureus N315 Length = 311 Score = 120 bits (302), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 66/204 (32%), Positives = 106/204 (51%), Gaps = 1/204 (0%) Query: 45 VAGVCREHGIACITPADPKSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMH 104 V V ++ + P + L Q+ D I + + +LP +LA K GA N+H Sbjct: 48 VKKVAMKYDLPVYQPEKLSGSEELEQLLQLDVDLIVTAAFGQLLPESLLALPKLGAINVH 107 Query: 105 GSLLPKYRGRVPINWAVLHGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGK 164 SLLPKYRG PI+ A++ GE ETG T+ M K DAG I++Q ++ I +D + K Sbjct: 108 ASLLPKYRGGAPIHQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDNVGTMHDK 167 Query: 165 VVVAAELTLWNVLPAMLSGRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAV 224 + V L LP+++ G S+P D ++ ++ + ED RI W + R+V N +R + Sbjct: 168 LSVLGADLLKETLPSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGRQVFNQIRGL 227 Query: 225 APPYPGAFEEIADDKITVTRTRLV 248 + P+P A+ + D + + LV Sbjct: 228 S-PWPVAYTTMDDTNLKIYDAELV 250 >BH2508 [J] COG0223 Methionyl-tRNA formyltransferase Bha Bacillus halodurans Length = 317 Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 73/235 (31%), Positives = 111/235 (47%), Gaps = 4/235 (1%) Query: 1 MNAVVFAYHDVGVRCLKVLLARGVQVSLVVTHEDSATEN---IWFGSVAGVCREHGIACI 57 M V D V L+ L+ G ++ VVT D + V +H I + Sbjct: 1 MKIVFMGTPDFSVPVLRRLIEDGYTIAAVVTQPDRPVGRKRVLTPPPVKVEAEKHQIPVL 60 Query: 58 TPADPKSPQLLAQVQAAQPDFIFSFYYRHMLPVEVLAAAKRGAYNMHGSLLPKYRGRVPI 117 P + L ++ + +PD I + + +LP +L K G N+H SLLPKYRG PI Sbjct: 61 QPEKIRDEAELERLFSFEPDLIVTAAFGQILPNALLEYPKHGCINVHASLLPKYRGGAPI 120 Query: 118 NWAVLHGETETGATLHEMTVKPDAGAIVAQTSVPILPDDTAHEVFGKVVVAAELTLWNVL 177 + A++ GE ETG T+ M K DAG I+ Q +VPI DD + K+ A L + Sbjct: 121 HQAIIDGEKETGITIMYMAEKLDAGDILTQVTVPIADDDHVGSLHNKLSEAGAALLAKTI 180 Query: 178 PAMLSGRTPSMPNDLSKGSYYGGRKPEDGRIDWRRTAREVHNLVRAVAPPYPGAF 232 P ++ G S+P D ++ E IDWR+ ++N +R + P+P A+ Sbjct: 181 PPLIKGELQSIPQDDQLATFAPNITREKEEIDWRKEGERIYNQIRGLH-PWPVAY 234