BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0090.p (481 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1311 [L] COG0305 Replicative DNA helicase Rso Ralstonia solan... 788 0.0 NMB0885 [L] COG0305 Replicative DNA helicase Nme Neisseria menin... 599 e-171 NMA1105 [L] COG0305 Replicative DNA helicase NmA Neisseria menin... 597 e-170 PA4931 [L] COG0305 Replicative DNA helicase Pae Pseudomonas aeru... 551 e-156 VC0371 [L] COG0305 Replicative DNA helicase Vch Vibrio cholerae 517 e-146 XF0361 [L] COG0305 Replicative DNA helicase Xfa Xylella fastidio... 504 e-142 ZdnaB [L] COG0305 Replicative DNA helicase EcZ Escherichia coli ... 501 e-141 ECs5034 [L] COG0305 Replicative DNA helicase Ecs Escherichia col... 501 e-141 dnaB [L] COG0305 Replicative DNA helicase Eco Escherichia coli K12 501 e-141 YPO0320 [L] COG0305 Replicative DNA helicase Ype Yersinia pestis 499 e-141 >RSc1311 [L] COG0305 Replicative DNA helicase Rso Ralstonia solanacearum Length = 473 Score = 788 bits (2036), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/469 (82%), Positives = 430/469 (91%), Gaps = 5/469 (1%) Query: 4 MKESSRGNPEFFRGQKESSDPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAE 63 M R NP +DPQ+++L+VPPHSIEAEQSVLGGLLLDNAAWDRIADF++ Sbjct: 1 MNAPRRYNP----AMNAPTDPQLESLKVPPHSIEAEQSVLGGLLLDNAAWDRIADFINEH 56 Query: 64 DFYRYDHRIIFEHIVKLINSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAAN 123 DFYRYDHR+IF +I KLI+ KPADVITVYE + +GKAEEVGGL YLNALAQNTPSAAN Sbjct: 57 DFYRYDHRLIFHNIGKLISQAKPADVITVYEQLQAAGKAEEVGGLAYLNALAQNTPSAAN 116 Query: 124 IRRYAEIVRDRGILRKLITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQG 183 IRRYAEIVRDRG+LR+L+T+ADEIS AFNPQG+DV+ +LDEAESK+FAIAEEG+RG +G Sbjct: 117 IRRYAEIVRDRGVLRQLVTIADEISAGAFNPQGRDVRQLLDEAESKVFAIAEEGARGQKG 176 Query: 184 FMEIQPLLTQVVERIDELYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGK 243 F+EIQPLLTQVVERIDELY+RD+ SDITGVPTGF+DLD+MTSG+Q GDLIIVAGRPSMGK Sbjct: 177 FLEIQPLLTQVVERIDELYHRDNQSDITGVPTGFVDLDRMTSGMQGGDLIIVAGRPSMGK 236 Query: 244 TAFSINIGEHVAIESGLPVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRL 303 TAFS+NIGEHVA+E GLPVAVFSMEM G QLAMRMLGSVGRLDQHRLRTGRLLDEDWPRL Sbjct: 237 TAFSLNIGEHVAVEQGLPVAVFSMEMAGTQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRL 296 Query: 304 THAIQKMNDAQFYIDETPALSPIELRARSRRLARQCGKLGLIIIDYLQLMSGNGGSSSEN 363 THAIQKMNDAQ +IDETPAL+P+ELRARSRRLARQCG+LGLIIIDYLQLMSG+GG EN Sbjct: 297 THAIQKMNDAQLFIDETPALNPMELRARSRRLARQCGQLGLIIIDYLQLMSGSGG-GGEN 355 Query: 364 RASEISEISRSLKGLAKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVIL 423 RA+EISEISRSLKGLAKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVIL Sbjct: 356 RATEISEISRSLKGLAKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVIL 415 Query: 424 FIYRDEVYNPDSPDKGTAEIIIGKQRNGPIGSIRLSFLGMYTKYDNYIG 472 FIYRD+VYNPDSPDKGTAEIIIGKQRNGPIG++RL+FLG YTK+DN+ G Sbjct: 416 FIYRDQVYNPDSPDKGTAEIIIGKQRNGPIGTVRLTFLGEYTKFDNFTG 464 >NMB0885 [L] COG0305 Replicative DNA helicase Nme Neisseria meningitidis MC58 Length = 468 Score = 599 bits (1544), Expect = e-171, Method: Compositional matrix adjust. Identities = 306/450 (68%), Positives = 368/450 (81%), Gaps = 3/450 (0%) Query: 21 SSDPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYRYDHRIIFEHIVKL 80 S D ++ AL +PPHS+EAEQSVLGGL+L+N AWDRIAD VS EDFYR++HR+IF I KL Sbjct: 9 SEDREVGALSLPPHSMEAEQSVLGGLMLENPAWDRIADVVSGEDFYRHEHRLIFRSIAKL 68 Query: 81 INSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRYAEIVRDRGILRKL 140 IN ++PADVITV E + + + E GG YL LAQNTPSAANIRRYAEIVR+R I+R+L Sbjct: 69 INESRPADVITVQEDLQRNEELEAAGGFEYLITLAQNTPSAANIRRYAEIVRERSIMRQL 128 Query: 141 ITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEIQPLLTQVVERIDE 200 V EI+ +A+NPQG+D +LDEAE+K+F IAE ++ QGF+E+ LL +VV+RID Sbjct: 129 AEVGTEIARSAYNPQGRDAGQLLDEAENKVFQIAESTAKSKQGFLEMPDLLKEVVQRIDM 188 Query: 201 LYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFSINIGEHVAIESGL 260 LY+RD+ ++TGVPTGF+DLDK TSGLQPGDLIIVAGRPSMGKTAFSINI EHVA+E L Sbjct: 189 LYSRDNPDEVTGVPTGFIDLDKKTSGLQPGDLIIVAGRPSMGKTAFSINIAEHVAVEGRL 248 Query: 261 PVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHAIQKMNDAQFYIDET 320 PVAVFSMEMGGAQL MRMLGSVGRLDQ L+TGRL DE W RL A+ K++DA YIDET Sbjct: 249 PVAVFSMEMGGAQLVMRMLGSVGRLDQSVLKTGRLEDEHWGRLNEAVVKLSDAPVYIDET 308 Query: 321 PALSPIELRARSRRLARQC-GKLGLIIIDYLQLMSGNGGSSSENRASEISEISRSLKGLA 379 P L+ +ELRAR+RRLARQ KLGLI+IDYLQLM+G+G S+NRASE+ EISRSLK LA Sbjct: 309 PGLTALELRARARRLARQFNNKLGLIVIDYLQLMAGSG--RSDNRASELGEISRSLKALA 366 Query: 380 KELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEVYNPDSPDKG 439 KEL P+IALSQL+R++E R +KRP+MSDLRESGAIEQDAD+I+F+YRDE YN DSP KG Sbjct: 367 KELQVPIIALSQLSRTVESRTDKRPMMSDLRESGAIEQDADLIMFMYRDEYYNQDSPMKG 426 Query: 440 TAEIIIGKQRNGPIGSIRLSFLGMYTKYDN 469 AE IIGK RNGP+G I L++ G +TK+DN Sbjct: 427 LAECIIGKHRNGPVGKIFLTWTGQFTKFDN 456 >NMA1105 [L] COG0305 Replicative DNA helicase NmA Neisseria meningitidis Z2491 Length = 468 Score = 597 bits (1538), Expect = e-170, Method: Compositional matrix adjust. Identities = 305/450 (67%), Positives = 367/450 (81%), Gaps = 3/450 (0%) Query: 21 SSDPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYRYDHRIIFEHIVKL 80 S D ++ AL +PPHS+EAEQSVLGGL+L+N AWDRIAD VS EDFYR++HR+IF I KL Sbjct: 9 SEDREVGALSLPPHSMEAEQSVLGGLMLENPAWDRIADVVSGEDFYRHEHRLIFRSIAKL 68 Query: 81 INSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRYAEIVRDRGILRKL 140 IN ++PADVITV E + + + E GG YL LAQNTPSAANIRRYAEIVR+R I+R+L Sbjct: 69 INESRPADVITVQEDLQRNEELEAAGGFEYLITLAQNTPSAANIRRYAEIVRERSIMRQL 128 Query: 141 ITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEIQPLLTQVVERIDE 200 V EI+ +A+NPQG+D +LDEAE+K+F IAE ++ QGF+E+ LL +VV+RID Sbjct: 129 AEVGTEIARSAYNPQGRDAGQLLDEAENKVFQIAESTAKSKQGFLEMPDLLKEVVQRIDM 188 Query: 201 LYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFSINIGEHVAIESGL 260 LY+RD+ ++TGV TGF+DLDK TSGLQPGDLIIVAGRPSMGKTAFSINI EHVA+E L Sbjct: 189 LYSRDNPDEVTGVSTGFIDLDKKTSGLQPGDLIIVAGRPSMGKTAFSINIAEHVAVEGKL 248 Query: 261 PVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHAIQKMNDAQFYIDET 320 PVAVFSMEMGGAQL MRMLGSVGRLDQ L+TGRL DE W RL A+ K++DA YIDET Sbjct: 249 PVAVFSMEMGGAQLVMRMLGSVGRLDQSVLKTGRLEDEHWGRLNEAVVKLSDAPVYIDET 308 Query: 321 PALSPIELRARSRRLARQC-GKLGLIIIDYLQLMSGNGGSSSENRASEISEISRSLKGLA 379 P L+ +ELRAR+RRLARQ KLGLI+IDYLQLM+G+G S+NRASE+ EISRSLK LA Sbjct: 309 PGLTALELRARARRLARQFNNKLGLIVIDYLQLMAGSG--RSDNRASELGEISRSLKALA 366 Query: 380 KELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEVYNPDSPDKG 439 KEL P+IALSQL+R++E R +KRP+MSDLRESGAIEQDAD+I+F+YRDE YN DSP KG Sbjct: 367 KELQVPIIALSQLSRTVESRTDKRPMMSDLRESGAIEQDADLIMFMYRDEYYNQDSPMKG 426 Query: 440 TAEIIIGKQRNGPIGSIRLSFLGMYTKYDN 469 AE IIGK RNGP+G I L++ G +TK+DN Sbjct: 427 LAECIIGKHRNGPVGKIFLTWTGQFTKFDN 456 >PA4931 [L] COG0305 Replicative DNA helicase Pae Pseudomonas aeruginosa Length = 464 Score = 551 bits (1419), Expect = e-156, Method: Compositional matrix adjust. Identities = 267/450 (59%), Positives = 349/450 (77%), Gaps = 4/450 (0%) Query: 20 ESSDPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYRYDHRIIFEHIVK 79 E D + AL+VPPHSIEAEQ+VLGGL+LDN AW+R++D VS DFYR+DHR+IF I K Sbjct: 8 EQYDLETTALKVPPHSIEAEQAVLGGLMLDNNAWERVSDSVSDGDFYRHDHRLIFRAIYK 67 Query: 80 LINSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRYAEIVRDRGILRK 139 L + +P DV+T+ E + G+ +VGGL YL LA+N PS ANI+ YA+I+R+R LR+ Sbjct: 68 LAEANQPIDVVTLSEQLEKEGQLAQVGGLAYLGELAKNIPSVANIKAYAQIIRERATLRQ 127 Query: 140 LITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEIQPLLTQVVERID 199 LI +++EI+ +AF+P+G+ +LDEAE KIF +AE + + G + I +L + ++RID Sbjct: 128 LIGISNEIADSAFHPEGRGANEILDEAERKIFEVAEARPK-TGGPVGISDILVKTIDRID 186 Query: 200 ELYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFSINIGEHVAIESG 259 L+N ++ +TGV TGF DLD+ TSGLQP DLIIVAGRPSMGKT F++N+ E+ + + Sbjct: 187 YLFN--TTEALTGVSTGFTDLDEKTSGLQPADLIIVAGRPSMGKTTFAMNLVENAVMRTD 244 Query: 260 LPVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHAIQKMNDAQFYIDE 319 V V+S+EM + MRML S+GR+DQ ++R+G+L DEDWPRLT AI +ND + +ID+ Sbjct: 245 KAVLVYSLEMPSDSIVMRMLSSLGRIDQTKVRSGKLDDEDWPRLTSAINLLNDKKLFIDD 304 Query: 320 TPALSPIELRARSRRLARQCGKLGLIIIDYLQLMSGNGGSSSENRASEISEISRSLKGLA 379 T +SP E+RAR+RRL R+ G L LI+IDYLQLM GSS +NR +EISEISRSLK LA Sbjct: 305 TAGISPSEMRARTRRLVREHGDLALIMIDYLQLMQ-IPGSSGDNRTNEISEISRSLKALA 363 Query: 380 KELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEVYNPDSPDKG 439 KE NCPVIALSQLNRSLEQRPNKRPV SDLRESGAIEQDADVI+F+YRDEVY+P++ KG Sbjct: 364 KEFNCPVIALSQLNRSLEQRPNKRPVNSDLRESGAIEQDADVIMFVYRDEVYHPETEFKG 423 Query: 440 TAEIIIGKQRNGPIGSIRLSFLGMYTKYDN 469 AEIIIGKQRNGPIG++RL+F+G YT+++N Sbjct: 424 VAEIIIGKQRNGPIGTVRLAFIGKYTRFEN 453 >VC0371 [L] COG0305 Replicative DNA helicase Vch Vibrio cholerae Length = 468 Score = 517 bits (1332), Expect = e-146, Method: Compositional matrix adjust. Identities = 254/451 (56%), Positives = 340/451 (75%), Gaps = 4/451 (0%) Query: 23 DPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYRYDHRIIFEHIVKLIN 82 D Q+DA++VPPHS+EAEQSV+GGLLLDN WD +++ V +DFY HR+IF+ + ++ Sbjct: 15 DAQVDAIKVPPHSLEAEQSVIGGLLLDNERWDTVSEHVMTQDFYSRPHRLIFDGVKSILE 74 Query: 83 STKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRYAEIVRDRGILRKLIT 142 + KP D+IT+ E + + E+VGG YL LA+NTPSAANI YAEIV +R ++R LI Sbjct: 75 AGKPLDLITLSEYLEQREQLEDVGGFAYLADLAKNTPSAANINAYAEIVAERALVRNLIG 134 Query: 143 VADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEIQPLLTQVVERIDELY 202 VA+EI+ ++PQG++ + +LD AESK+FAIAE + ++G + +L + +ERI+ LY Sbjct: 135 VANEIADAGYDPQGRNAEDLLDLAESKVFAIAEARTSENEGPKNVDSILERTLERIELLY 194 Query: 203 NRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFSINIGEHVAIESGLPV 262 + +TGV TGF DL+K T+GLQ DLIIVA RPSMGKT F++N+ E+ A+E PV Sbjct: 195 -KTPQDGVTGVNTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMEQDKPV 253 Query: 263 AVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHAIQ-KMNDAQFYIDETP 321 +FS+EM Q+ MRML S+ R+DQ ++RTG+L DEDW R++ + M YID++ Sbjct: 254 LIFSLEMPAEQIMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGILMEKKNMYIDDSS 313 Query: 322 ALSPIELRARSRRLARQCGKLGLIIIDYLQLMSGNGGSSSENRASEISEISRSLKGLAKE 381 L+P E+R+R+RR+AR+ G L LI++DYLQLM + ++NR EI+EISRSLK LAKE Sbjct: 314 GLTPTEVRSRARRIAREHGGLSLIMVDYLQLM--RVPALTDNRTLEIAEISRSLKALAKE 371 Query: 382 LNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEVYNPDSPDKGTA 441 LN PV+ALSQLNRSLEQR +KRPV SDLRESG+IEQDAD+I+FIYRDEVY+PDSP KGTA Sbjct: 372 LNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHPDSPLKGTA 431 Query: 442 EIIIGKQRNGPIGSIRLSFLGMYTKYDNYIG 472 EIIIGKQRNGPIGS+RL+F G Y+++DNY G Sbjct: 432 EIIIGKQRNGPIGSVRLTFQGHYSRFDNYAG 462 >XF0361 [L] COG0305 Replicative DNA helicase Xfa Xylella fastidiosa 9a5c Length = 471 Score = 504 bits (1299), Expect = e-142, Method: Compositional matrix adjust. Identities = 256/455 (56%), Positives = 332/455 (72%), Gaps = 8/455 (1%) Query: 18 QKESSDPQ---IDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYRYDHRIIF 74 Q+E D + +D LRVPPHS+EAEQ+VLGGL+L A D+I D ++ DFYR DHR+I+ Sbjct: 12 QREPGDREALRVDPLRVPPHSVEAEQAVLGGLMLAPDALDKINDRLTENDFYRRDHRMIY 71 Query: 75 EHIVKLINSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRYAEIVRDR 134 I L +P DV+T+ E + G E V YL LA TPSAANI YAEIVRD+ Sbjct: 72 RAICDLSRKMRPFDVVTLGEWFESQGMLEVVDHGAYLIELASTTPSAANIVAYAEIVRDK 131 Query: 135 GILRKLITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEIQPLLTQV 194 +LR+LI V +I + F P+G++ +L EAE +F IAE G+RG F+ + L Sbjct: 132 AVLRQLIEVGTKIVNDGFQPEGRESIDLLAEAEKSVFGIAETGARGRIDFVAMPGALKDA 191 Query: 195 VERIDELYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFSINIGEHV 254 E++ + + ++ S++TG+PTG+ D D M++GLQP DLI++A RP+MGKT F++NI E+V Sbjct: 192 FEQLRDRF--ENGSNVTGLPTGYNDFDAMSAGLQPTDLIVLAARPAMGKTTFALNIAEYV 249 Query: 255 AIESGLPVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHAIQKMNDAQ 314 AI+S VAVFSMEM AQLAMR++ S GR++ RLRTG+L DEDW R+T AI+ + + + Sbjct: 250 AIKSKKTVAVFSMEMSAAQLAMRLISSNGRINAQRLRTGQLEDEDWARVTGAIKMLKETK 309 Query: 315 FYIDETPALSPIELRARSRRLARQCGKLGLIIIDYLQLMSGNGGSSSENRASEISEISRS 374 +ID+TP +SP LR++ RRL R+ LGL+++DYLQLMS G +SENRA+EISEISRS Sbjct: 310 IFIDDTPGVSPEVLRSKCRRLKRE-HDLGLVVVDYLQLMSVPG--NSENRATEISEISRS 366 Query: 375 LKGLAKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEVYNPD 434 LKGLAKELN PVIALSQLNRSLE R +K PVM+DLRESGAIEQDAD+I+FIYRDE YN D Sbjct: 367 LKGLAKELNVPVIALSQLNRSLETRTDKHPVMADLRESGAIEQDADMIVFIYRDEYYNKD 426 Query: 435 SPDKGTAEIIIGKQRNGPIGSIRLSFLGMYTKYDN 469 SPDKG AEIIIGK R+GP GS +L F G YT++DN Sbjct: 427 SPDKGLAEIIIGKHRSGPTGSCKLKFFGEYTRFDN 461 >ZdnaB [L] COG0305 Replicative DNA helicase EcZ Escherichia coli O157:H7 EDL933 Length = 471 Score = 501 bits (1289), Expect = e-141, Method: Compositional matrix adjust. Identities = 255/469 (54%), Positives = 342/469 (72%), Gaps = 12/469 (2%) Query: 10 GNPEFFRGQKE--SSDPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYR 67 GN F + Q E DPQ+ L+VPPHSIEAEQSVLGGL+LDN WD +A+ V A+DFY Sbjct: 3 GNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYT 62 Query: 68 YDHRIIFEHIVKLINSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRY 127 HR IF + +L S P D+IT+ E++ G+ + VGG YL L++NTPSAANI Y Sbjct: 63 RPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISSY 122 Query: 128 AEIVRDRGILRKLITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEI 187 A+IVR+R ++R++I+VA+EI+ F+PQG+ + +LD AES++F IAE + +G I Sbjct: 123 ADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRANKDEGPKNI 182 Query: 188 QPLLTQVVERIDELYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFS 247 +L V RI++L+ + +TGV TG+ DL+K T+GLQP DLIIVA RPSMGKT F+ Sbjct: 183 ADVLDATVARIEQLFQQPHDG-VTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFA 241 Query: 248 INIGEHVAIESGLPVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHA- 306 +N+ E+ A+ PV +FS+EM Q+ MR L S+ R+DQ ++RTG+L DEDW R++ Sbjct: 242 MNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTM 301 Query: 307 ---IQKMNDAQFYIDETPALSPIELRARSRRLARQCGKLGLIIIDYLQLMSGNGGSSSEN 363 ++K N YID++ L+P E+R+R+RR+AR+ G +GLI+IDYLQLM + S+N Sbjct: 302 GILLEKRN---IYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLM--RVPALSDN 356 Query: 364 RASEISEISRSLKGLAKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVIL 423 R EI+EISRSLK LAKELN PV+ALSQLNRSLEQR +KRPV SDLRESG+IEQDAD+I+ Sbjct: 357 RTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIM 416 Query: 424 FIYRDEVYNPDSPDKGTAEIIIGKQRNGPIGSIRLSFLGMYTKYDNYIG 472 FIYRDEVY+ +S KG AEIIIGKQRNGPIG++RL+F G ++++DNY G Sbjct: 417 FIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAG 465 >ECs5034 [L] COG0305 Replicative DNA helicase Ecs Escherichia coli O157:H7 Length = 471 Score = 501 bits (1289), Expect = e-141, Method: Compositional matrix adjust. Identities = 255/469 (54%), Positives = 342/469 (72%), Gaps = 12/469 (2%) Query: 10 GNPEFFRGQKE--SSDPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYR 67 GN F + Q E DPQ+ L+VPPHSIEAEQSVLGGL+LDN WD +A+ V A+DFY Sbjct: 3 GNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYT 62 Query: 68 YDHRIIFEHIVKLINSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRY 127 HR IF + +L S P D+IT+ E++ G+ + VGG YL L++NTPSAANI Y Sbjct: 63 RPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISSY 122 Query: 128 AEIVRDRGILRKLITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEI 187 A+IVR+R ++R++I+VA+EI+ F+PQG+ + +LD AES++F IAE + +G I Sbjct: 123 ADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRANKDEGPKNI 182 Query: 188 QPLLTQVVERIDELYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFS 247 +L V RI++L+ + +TGV TG+ DL+K T+GLQP DLIIVA RPSMGKT F+ Sbjct: 183 ADVLDATVARIEQLFQQPHDG-VTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFA 241 Query: 248 INIGEHVAIESGLPVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHA- 306 +N+ E+ A+ PV +FS+EM Q+ MR L S+ R+DQ ++RTG+L DEDW R++ Sbjct: 242 MNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTM 301 Query: 307 ---IQKMNDAQFYIDETPALSPIELRARSRRLARQCGKLGLIIIDYLQLMSGNGGSSSEN 363 ++K N YID++ L+P E+R+R+RR+AR+ G +GLI+IDYLQLM + S+N Sbjct: 302 GILLEKRN---IYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLM--RVPALSDN 356 Query: 364 RASEISEISRSLKGLAKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVIL 423 R EI+EISRSLK LAKELN PV+ALSQLNRSLEQR +KRPV SDLRESG+IEQDAD+I+ Sbjct: 357 RTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIM 416 Query: 424 FIYRDEVYNPDSPDKGTAEIIIGKQRNGPIGSIRLSFLGMYTKYDNYIG 472 FIYRDEVY+ +S KG AEIIIGKQRNGPIG++RL+F G ++++DNY G Sbjct: 417 FIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAG 465 >dnaB [L] COG0305 Replicative DNA helicase Eco Escherichia coli K12 Length = 471 Score = 501 bits (1289), Expect = e-141, Method: Compositional matrix adjust. Identities = 255/469 (54%), Positives = 342/469 (72%), Gaps = 12/469 (2%) Query: 10 GNPEFFRGQKE--SSDPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYR 67 GN F + Q E DPQ+ L+VPPHSIEAEQSVLGGL+LDN WD +A+ V A+DFY Sbjct: 3 GNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYT 62 Query: 68 YDHRIIFEHIVKLINSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRY 127 HR IF + +L S P D+IT+ E++ G+ + VGG YL L++NTPSAANI Y Sbjct: 63 RPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAY 122 Query: 128 AEIVRDRGILRKLITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEI 187 A+IVR+R ++R++I+VA+EI+ F+PQG+ + +LD AES++F IAE + +G I Sbjct: 123 ADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRANKDEGPKNI 182 Query: 188 QPLLTQVVERIDELYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFS 247 +L V RI++L+ + +TGV TG+ DL+K T+GLQP DLIIVA RPSMGKT F+ Sbjct: 183 ADVLDATVARIEQLFQQPHDG-VTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFA 241 Query: 248 INIGEHVAIESGLPVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHA- 306 +N+ E+ A+ PV +FS+EM Q+ MR L S+ R+DQ ++RTG+L DEDW R++ Sbjct: 242 MNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTM 301 Query: 307 ---IQKMNDAQFYIDETPALSPIELRARSRRLARQCGKLGLIIIDYLQLMSGNGGSSSEN 363 ++K N YID++ L+P E+R+R+RR+AR+ G +GLI+IDYLQLM + S+N Sbjct: 302 GILLEKRN---IYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLM--RVPALSDN 356 Query: 364 RASEISEISRSLKGLAKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVIL 423 R EI+EISRSLK LAKELN PV+ALSQLNRSLEQR +KRPV SDLRESG+IEQDAD+I+ Sbjct: 357 RTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIM 416 Query: 424 FIYRDEVYNPDSPDKGTAEIIIGKQRNGPIGSIRLSFLGMYTKYDNYIG 472 FIYRDEVY+ +S KG AEIIIGKQRNGPIG++RL+F G ++++DNY G Sbjct: 417 FIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAG 465 >YPO0320 [L] COG0305 Replicative DNA helicase Ype Yersinia pestis Length = 468 Score = 499 bits (1285), Expect = e-141, Method: Compositional matrix adjust. Identities = 246/454 (54%), Positives = 335/454 (73%), Gaps = 4/454 (0%) Query: 20 ESSDPQIDALRVPPHSIEAEQSVLGGLLLDNAAWDRIADFVSAEDFYRYDHRIIFEHIVK 79 E D Q++ L++PPHS+EAEQSVLGGL+LDN WD +++ V+++DF+ HR IF + + Sbjct: 12 EPRDRQMEGLKLPPHSLEAEQSVLGGLMLDNERWDNVSERVASKDFFSRPHRRIFTEMQR 71 Query: 80 LINSTKPADVITVYEAMSTSGKAEEVGGLVYLNALAQNTPSAANIRRYAEIVRDRGILRK 139 L+ ++KP D+IT+ E++ G + VGG YL L++NTPSAANI YA+IVR+R ++R+ Sbjct: 72 LLENSKPIDLITLSESLEQKGDLDSVGGFAYLAELSKNTPSAANIGAYADIVRERAVVRE 131 Query: 140 LITVADEISGNAFNPQGKDVKSMLDEAESKIFAIAEEGSRGSQGFMEIQPLLTQVVERID 199 +I+VA+EI+ ++PQG+ + +LD AESK+F IAE + +G + +L V RI+ Sbjct: 132 MISVANEIADAGYDPQGRSSEDLLDLAESKVFQIAESRASKDEGPKSVDRILEDTVARIE 191 Query: 200 ELYNRDSSSDITGVPTGFMDLDKMTSGLQPGDLIIVAGRPSMGKTAFSINIGEHVAIESG 259 +LY R +TGV TGF DLDK T+GLQ DLIIVA RPSMGKT F++N+ E+ A+ Sbjct: 192 QLYQRPHDG-VTGVSTGFTDLDKKTAGLQKSDLIIVAARPSMGKTTFAMNLCENAAMMQD 250 Query: 260 LPVAVFSMEMGGAQLAMRMLGSVGRLDQHRLRTGRLLDEDWPRLTHAIQ-KMNDAQFYID 318 PV +FS+EM G Q+ MRML S+ +DQ R+RTG+L DEDW R++ + M YID Sbjct: 251 KPVLIFSLEMPGDQIMMRMLASLSHVDQTRIRTGQLDDEDWARISSTMGILMEKRNMYID 310 Query: 319 ETPALSPIELRARSRRLARQCGKLGLIIIDYLQLMSGNGGSSSENRASEISEISRSLKGL 378 ++ L+P E+R+R+RR+ R+ G L LI+IDYLQLM S S+NR EI+EISRSLK L Sbjct: 311 DSSGLTPTEVRSRARRIFREHGGLSLIMIDYLQLM--RVPSLSDNRTLEIAEISRSLKAL 368 Query: 379 AKELNCPVIALSQLNRSLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEVYNPDSPDK 438 AKEL PV+ALSQLNRSLEQR +KRPV SDLRESG+IEQDAD+I+FIYRDEVY+ +S +K Sbjct: 369 AKELQVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDEK 428 Query: 439 GTAEIIIGKQRNGPIGSIRLSFLGMYTKYDNYIG 472 G A+II+GKQRNGPIGS+RL F G ++++DNY G Sbjct: 429 GIAQIILGKQRNGPIGSVRLKFNGQWSRFDNYAG 462