BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0025.p (223 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc3874 [K] COG1309 Transcriptional regulator Atu Agrobacterium ... 212 5e-55 SMa1299 [K] COG1309 Transcriptional regulator Sme Sinorhizobium ... 167 2e-41 mll1598 [K] COG1309 Transcriptional regulator Mlo Mesorhizobium ... 97 3e-20 STM1213 [K] COG1309 Transcriptional regulator Sty Salmonella typ... 96 4e-20 ZycfQ [K] COG1309 Transcriptional regulator EcZ Escherichia coli... 92 1e-18 ECs1489 [K] COG1309 Transcriptional regulator Ecs Escherichia co... 92 1e-18 PA2931 [K] COG1309 Transcriptional regulator Pae Pseudomonas aer... 91 2e-18 ycfQ [K] COG1309 Transcriptional regulator Eco Escherichia coli K12 89 9e-18 AGl3469 [K] COG1309 Transcriptional regulator Atu Agrobacterium ... 88 2e-17 VCA0586 [K] COG1309 Transcriptional regulator Vch Vibrio cholerae 86 7e-17 >AGc3874 [K] COG1309 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 240 Score = 212 bits (540), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 100/206 (48%), Positives = 145/206 (70%) Query: 18 SSSSSAPSSRRRNPGRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQGSLYKA 77 ++++ S +R+ GRPREFD D+ALDGA+RVFS RGY S+ DL++AM+LAQGSLYKA Sbjct: 35 TNTTQTHSQEQRHRGRPREFDLDRALDGAIRVFSRRGYHATSVGDLTDAMELAQGSLYKA 94 Query: 78 FRDKQSLFLAALERYRTQRSEKLRRAIDAGATGRERLRNMLLFYAESAQGAAGRQGCLVV 137 F+DK+++F+A +ERYR ++E+ A+ G TG ERLR L+FYAE + G G GCLVV Sbjct: 95 FKDKKAIFIATMERYRIVQTERFEAAVAGGETGYERLRAGLMFYAERSHGGVGSDGCLVV 154 Query: 138 SSAVAITGFEPSVATQIASTLARNEALLGELIRQGQQDGSVAAHADPASTARLLLCLTQG 197 +A + + +A + + E ++ +I +GQ+DGSV + ADP AR +LC+ G Sbjct: 155 GAAADLAALDDDIAVVVERAVKARERIVARIITEGQKDGSVHSTADPDDLARAMLCMMYG 214 Query: 198 MRVVGKAGRSRKEMLALVDVALKVLD 223 MRVVGK GR+ K+M+A+VD+A+K+ D Sbjct: 215 MRVVGKTGRTLKDMVAVVDIAMKLAD 240 >SMa1299 [K] COG1309 Transcriptional regulator Sme Sinorhizobium meliloti Length = 203 Score = 167 bits (422), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 86/199 (43%), Positives = 126/199 (63%) Query: 25 SSRRRNPGRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQGSLYKAFRDKQSL 84 S+ R GRPREFD +QALD A+R+FSE+GY G SI++L M L GS+YKAFRDK+ + Sbjct: 5 STSHRRVGRPREFDINQALDAAIRIFSEKGYHGTSIAELKTEMGLTAGSIYKAFRDKRDV 64 Query: 85 FLAALERYRTQRSEKLRRAIDAGATGRERLRNMLLFYAESAQGAAGRQGCLVVSSAVAIT 144 F+AA +RY+ R++ L +A+ + +TGRE++ ++ FYA SA G GR+GCL + +AV + Sbjct: 65 FVAAYDRYKQIRADLLDQALFSASTGREKIARVVGFYAMSACGETGRRGCLAIGAAVELV 124 Query: 145 GFEPSVATQIASTLARNEALLGELIRQGQQDGSVAAHADPASTARLLLCLTQGMRVVGKA 204 + +A ++ + A L IR GQ DGS+ DPA+TA L QG+R+ GK Sbjct: 125 LSDAEIADRVGRHNRKLVARLEGFIRDGQLDGSIRQDVDPAATALALFSYLQGVRIAGKT 184 Query: 205 GRSRKEMLALVDVALKVLD 223 +ML + L++LD Sbjct: 185 AELENQMLPSAEAVLRILD 203 >mll1598 [K] COG1309 Transcriptional regulator Mlo Mesorhizobium loti Length = 209 Score = 97.1 bits (240), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 64/191 (33%), Positives = 95/191 (49%) Query: 32 GRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQGSLYKAFRDKQSLFLAALER 91 GRPR FD D+ALD A+ +F E GY S++ L EAM L +Y AF DK++LF AL R Sbjct: 10 GRPRAFDPDRALDAAMHLFWEHGYEATSLAMLREAMGLTPPQIYNAFTDKETLFRKALTR 69 Query: 92 YRTQRSEKLRRAIDAGATGRERLRNMLLFYAESAQGAAGRQGCLVVSSAVAITGFEPSVA 151 Y A+ A E +R +LL AE+ GCL VS A+A + ++A Sbjct: 70 YHETEIGFALDALSAPVPTPEAIRRLLLGAAEAYSRPGKPGGCLFVSGALAASPRAQAIA 129 Query: 152 TQIASTLARNEALLGELIRQGQQDGSVAAHADPASTARLLLCLTQGMRVVGKAGRSRKEM 211 ++ + +EA + E + GQ G + S A+ + + GM + + G S +E+ Sbjct: 130 DELKAYRKASEAAIAERLAMGQAAGDLPEGFSVESFAKYIAGVMNGMSIQARDGASAEEL 189 Query: 212 LALVDVALKVL 222 + AL L Sbjct: 190 RIMAQTALAAL 200 >STM1213 [K] COG1309 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 211 Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 58/209 (27%), Positives = 101/209 (48%), Gaps = 5/209 (2%) Query: 15 MPASSSSSAPSSRRRNPGRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQGSL 74 M ++S A SR GRP+ FD + ALD A+ +F + GY S++DL EA +L Sbjct: 1 MTTDTTSCAKKSR----GRPKVFDREAALDKAMTLFWQHGYEATSLADLVEATGAKAPTL 56 Query: 75 YKAFRDKQSLFLAALERYRTQRSEKLRRAIDAGATGRER-LRNMLLFYAESAQGAAGRQG 133 Y F +K+ LF A L+RY T+ + K + E L + A G Sbjct: 57 YAEFTNKKGLFRAVLDRYITRFASKHEAQLFCEEKSVESALEDYFTEIAACFTSTDTPAG 116 Query: 134 CLVVSSAVAITGFEPSVATQIASTLARNEALLGELIRQGQQDGSVAAHADPASTARLLLC 193 C +++++ + +A + S A E L + +RQ Q+ G + AH +P + A + C Sbjct: 117 CFMINTSATLAASSRDIARTVKSRHAMQEQTLIQFLRQRQERGEIPAHCNPQALAEYINC 176 Query: 194 LTQGMRVVGKAGRSRKEMLALVDVALKVL 222 + QGM + + G + ++++ + L++ Sbjct: 177 ILQGMSISAREGATFEQLMQITRTTLRIW 205 >ZycfQ [K] COG1309 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 236 Score = 91.7 bits (226), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 59/212 (27%), Positives = 96/212 (45%), Gaps = 5/212 (2%) Query: 12 NIFMPASSSSSAPSSRRRNPGRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQ 71 N M S+ SR GRP+ FD D ALD A+++F + GY S++DL EA Sbjct: 24 NGIMATDSTQCVKKSR----GRPKVFDRDAALDKAMKLFWQHGYEATSLADLVEATGAKA 79 Query: 72 GSLYKAFRDKQSLFLAALERYRTQRSEKLRRAIDAGATGRER-LRNMLLFYAESAQGAAG 130 +LY F +K+ LF A L+RY + + K + E L + A G Sbjct: 80 PTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFAAIANCFTGKDT 139 Query: 131 RQGCLVVSSAVAITGFEPSVATQIASTLARNEALLGELIRQGQQDGSVAAHADPASTARL 190 GC ++++ ++ +A + S A E L + + Q Q G + H D A Sbjct: 140 PAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGEIPTHCDVTHLAEF 199 Query: 191 LLCLTQGMRVVGKAGRSRKEMLALVDVALKVL 222 L C+ QGM + + G S ++++ + L++ Sbjct: 200 LNCIIQGMSISAREGASLEKLMQIAGTTLRLW 231 >ECs1489 [K] COG1309 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 236 Score = 91.7 bits (226), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 59/212 (27%), Positives = 96/212 (45%), Gaps = 5/212 (2%) Query: 12 NIFMPASSSSSAPSSRRRNPGRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQ 71 N M S+ SR GRP+ FD D ALD A+++F + GY S++DL EA Sbjct: 24 NGIMATDSTQCVKKSR----GRPKVFDRDAALDKAMKLFWQHGYEATSLADLVEATGAKA 79 Query: 72 GSLYKAFRDKQSLFLAALERYRTQRSEKLRRAIDAGATGRER-LRNMLLFYAESAQGAAG 130 +LY F +K+ LF A L+RY + + K + E L + A G Sbjct: 80 PTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFAAIANCFTGKDT 139 Query: 131 RQGCLVVSSAVAITGFEPSVATQIASTLARNEALLGELIRQGQQDGSVAAHADPASTARL 190 GC ++++ ++ +A + S A E L + + Q Q G + H D A Sbjct: 140 PAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGEIPTHCDVTHLAEF 199 Query: 191 LLCLTQGMRVVGKAGRSRKEMLALVDVALKVL 222 L C+ QGM + + G S ++++ + L++ Sbjct: 200 LNCIIQGMSISAREGASLEKLMQIAGTTLRLW 231 >PA2931 [K] COG1309 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 196 Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 70/191 (36%), Positives = 97/191 (50%), Gaps = 4/191 (2%) Query: 32 GRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQGSLYKAFRDKQSLFLAALER 91 GRPR FD D AL A+ VF RGY GAS++ L+EAM++ SLY AF K+ LF AL Sbjct: 5 GRPRAFDRDTALQRAMDVFWVRGYEGASLAALTEAMEIRPPSLYAAFGSKEGLFREALAH 64 Query: 92 YRTQRSEKLRRAIDAGATGRERLRNMLLFYAESAQGAAGRQGCLVVSSAVAITGFEPSVA 151 Y Q R +D + RE + +L +GCLVV + A+TG S A Sbjct: 65 YLGQHGRYRRDVLDGAPSAREGVAELLRETVARFCSDEFPRGCLVVLA--ALTGTPESEA 122 Query: 152 TQIASTLARNEA--LLGELIRQGQQDGSVAAHADPASTARLLLCLTQGMRVVGKAGRSRK 209 + A + R E+ L E +R+G DG +AA D A + G+ V K + Sbjct: 123 VRDALSAERGESIRLFRERMRRGIADGDLAADTDVEELATFYATVLFGLSVQAKDRVPCE 182 Query: 210 EMLALVDVALK 220 +LA+V+ AL+ Sbjct: 183 RLLAVVERALR 193 >ycfQ [K] COG1309 Transcriptional regulator Eco Escherichia coli K12 Length = 236 Score = 88.6 bits (218), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 58/212 (27%), Positives = 95/212 (44%), Gaps = 5/212 (2%) Query: 12 NIFMPASSSSSAPSSRRRNPGRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQ 71 N M S+ SR GRP+ FD D ALD A+++F + GY S++DL EA Sbjct: 24 NGIMATDSTQCVKKSR----GRPKVFDRDAALDKAMKLFWQHGYEATSLADLVEATGAKA 79 Query: 72 GSLYKAFRDKQSLFLAALERYRTQRSEKLRRAIDAGATGRER-LRNMLLFYAESAQGAAG 130 +LY F +K+ LF A L+RY + + K + E L + A Sbjct: 80 PTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFAAIANCFTSKDT 139 Query: 131 RQGCLVVSSAVAITGFEPSVATQIASTLARNEALLGELIRQGQQDGSVAAHADPASTARL 190 GC ++++ ++ +A + S A E L + + Q Q G + H D A Sbjct: 140 PAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGEIPPHCDVTHLAEF 199 Query: 191 LLCLTQGMRVVGKAGRSRKEMLALVDVALKVL 222 L C+ QGM + + G S ++++ + L++ Sbjct: 200 LNCIIQGMSISAREGASLEKLMQIAGTTLRLW 231 >AGl3469 [K] COG1309 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 219 Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 64/195 (32%), Positives = 93/195 (47%), Gaps = 2/195 (1%) Query: 25 SSRRRNPGRPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQGSLYKAFRDKQSL 84 ++R+R GRPR D + LD A R+F ERGY G SI+DL+ AM + SLY F K+ L Sbjct: 9 TTRKR--GRPRLLDRNTGLDIAARLFWERGYEGTSIADLTHAMGITPPSLYATFGSKEEL 66 Query: 85 FLAALERYRTQRSEKLRRAIDAGATGRERLRNMLLFYAESAQGAAGRQGCLVVSSAVAIT 144 F AL+ + Q+SE+ + A E L L AE +GC+V ++ + + Sbjct: 67 FRLALDHHIAQQSERRAGLLQAKIPAHEALAAYLYDIAEGDTQPDKPRGCIVSTAVLQHS 126 Query: 145 GFEPSVATQIASTLARNEALLGELIRQGQQDGSVAAHADPASTARLLLCLTQGMRVVGKA 204 SVA A+ +L + DG + D + AR + QGM Sbjct: 127 EENASVARATAALREGAIQILKARFDRAIHDGELPEQTDTDTLARFYGAIIQGMSAQACD 186 Query: 205 GRSRKEMLALVDVAL 219 G + + A+VDVAL Sbjct: 187 GACTETLKAVVDVAL 201 >VCA0586 [K] COG1309 Transcriptional regulator Vch Vibrio cholerae Length = 198 Score = 85.9 bits (211), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 56/175 (32%), Positives = 87/175 (49%), Gaps = 2/175 (1%) Query: 33 RPREFDADQALDGAVRVFSERGYAGASISDLSEAMQLAQGSLYKAFRDKQSLFLAALERY 92 R FD ++ L A+ +F ++GYA +ISDL + +Q+ + SLY AF DKQ L+ AL+RY Sbjct: 3 RKCNFDREEKLHQAMTLFWQKGYANTAISDLVDHLQINRFSLYNAFGDKQKLYYEALDRY 62 Query: 93 RTQRSEKLRRAIDAGATGRERLRNMLLFYAESAQGAAGRQGCLVVSSAVAITGFEPSVAT 152 S + ++ + L+ L +A A G +GC + ++ V + V Sbjct: 63 LNLVSSPALKDLELESAAWPELKAFLQHFA--ALQREGNRGCFMQNALVEHADTDDEVLN 120 Query: 153 QIASTLARNEALLGELIRQGQQDGSVAAHADPASTARLLLCLTQGMRVVGKAGRS 207 + + L+ + Q G +AAH S A L+L QGMRV+GKA R Sbjct: 121 KGHALFDHLLHLIARALNNAIQQGQIAAHLCADSLAPLVLTQMQGMRVLGKAQRH 175