BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0001.p (258 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2872 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Rso ... 394 e-110 BMEI1945 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme... 330 2e-90 SMc01153 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sme... 329 3e-90 AGc562 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Atu A... 325 6e-89 Rv1070c [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu ... 324 1e-88 MT1100 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC M... 324 1e-88 ML2402 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mle M... 312 4e-85 mll5584 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mlo ... 310 2e-84 CC0006 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ccr C... 285 8e-77 SSO2624 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso ... 243 2e-64 >RSc2872 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Rso Ralstonia solanacearum Length = 258 Score = 394 bits (1013), Expect = e-110, Method: Compositional matrix adjust. Identities = 193/257 (75%), Positives = 220/257 (85%) Query: 1 MSYENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKA 60 MSY++I VET +VGL+ L+RPKALNAL+D LM ELG ALLAFDA E IG +IITGS+KA Sbjct: 1 MSYQHILVETRGRVGLVTLNRPKALNALNDALMDELGAALLAFDADEGIGAMIITGSDKA 60 Query: 61 FAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFI 120 FAAGADI AMA YD+ V+K E+ITRNWET+RRIRKPVIAAVAGYALGGGCELAMMCD I Sbjct: 61 FAAGADIGAMADYDFATVYKNEYITRNWETIRRIRKPVIAAVAGYALGGGCELAMMCDII 120 Query: 121 IAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRI 180 +AAD A+FGQPEIKLG +PGAGGTQRLPRAVSKAKAMDL LT RMM A+EAERAGLVSR+ Sbjct: 121 LAADTARFGQPEIKLGTMPGAGGTQRLPRAVSKAKAMDLCLTARMMGADEAERAGLVSRV 180 Query: 181 VAADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQ 240 + ADKLL+EA+AAA IA AMM+K+S+N AYETTLSEG++ ER LF++ FATEDQ Sbjct: 181 IPADKLLDEALAAAETIAGFSLPTAMMIKESINAAYETTLSEGVRLERRLFHATFATEDQ 240 Query: 241 KEGMKAFLEKRQPVFKH 257 KEGM AFL KRQP FKH Sbjct: 241 KEGMHAFLGKRQPAFKH 257 >BMEI1945 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 293 Score = 330 bits (846), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 162/257 (63%), Positives = 201/257 (78%), Gaps = 1/257 (0%) Query: 1 MSYENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKA 60 M+YE I VET + VGLIRL+RP+ALNAL+ ++ EL +AL AFDA ++G +++TGSEKA Sbjct: 37 MAYETIIVETRDSVGLIRLNRPQALNALNRAVLEELTDALAAFDADGKVGAVVLTGSEKA 96 Query: 61 FAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFI 120 FAAGADI M +++D + + +W+ + RIRKP+IAAV+GYALGGGCELAMMCDFI Sbjct: 97 FAAGADIKEMQLINFVDAYLQDMFA-DWQKVDRIRKPIIAAVSGYALGGGCELAMMCDFI 155 Query: 121 IAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRI 180 IA NAKFGQPEI LG +PG GG+QRL R V K+KAMD+ LTGRMMDA EAER GLVSR+ Sbjct: 156 IAGSNAKFGQPEITLGAIPGMGGSQRLTRYVGKSKAMDMCLTGRMMDAAEAERCGLVSRV 215 Query: 181 VAADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQ 240 VA + LLEEA+ AA IA R M K++VNRAYETTL EG+++ER LF+S FATEDQ Sbjct: 216 VAPEALLEEALKAAERIASFSRVSVYMAKEAVNRAYETTLDEGLRFERRLFHSLFATEDQ 275 Query: 241 KEGMKAFLEKRQPVFKH 257 KEGM AF++KR P FK+ Sbjct: 276 KEGMSAFVDKRTPSFKN 292 >SMc01153 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sme Sinorhizobium meliloti Length = 257 Score = 329 bits (844), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 165/257 (64%), Positives = 200/257 (77%), Gaps = 1/257 (0%) Query: 1 MSYENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKA 60 MSYE + VET +VGLI L+RP+ALNAL+ LM EL AL AFDA +G I++ GSEKA Sbjct: 1 MSYETLLVETQGRVGLITLNRPQALNALNAVLMRELDAALKAFDADRAVGAIVLAGSEKA 60 Query: 61 FAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFI 120 FAAGADI M G D++D + +F+ WE + RKP+IAAV+G+ALGGGCELAMMCDFI Sbjct: 61 FAAGADIKEMQGLDFVDGYLADFLG-GWEHVANARKPMIAAVSGFALGGGCELAMMCDFI 119 Query: 121 IAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRI 180 IA++ AKFGQPEI LG++PG GG+QRL RAV KAKAMDL LTGRMMDA EAER+GLVSR+ Sbjct: 120 IASETAKFGQPEITLGVIPGMGGSQRLTRAVGKAKAMDLILTGRMMDAAEAERSGLVSRV 179 Query: 181 VAADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQ 240 VA D+LLEEA+ AA IA AMM K++VNR+ E TL+EG+++ER LF S FATEDQ Sbjct: 180 VAPDRLLEEALGAAEKIASFSLPAAMMAKEAVNRSLELTLAEGLRFERRLFQSLFATEDQ 239 Query: 241 KEGMKAFLEKRQPVFKH 257 KEGM AF+ KR+ FKH Sbjct: 240 KEGMAAFVAKRKAEFKH 256 >AGc562 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 288 Score = 325 bits (833), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 162/257 (63%), Positives = 198/257 (77%), Gaps = 1/257 (0%) Query: 1 MSYENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKA 60 + YE I VE ++VG+I L+RPK LNAL+ L+ EL L +F A + IG IIITGSEKA Sbjct: 32 VDYEMILVEKRDEVGVITLNRPKVLNALNSVLLKELRHILSSFSADDSIGAIIITGSEKA 91 Query: 61 FAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFI 120 FAAGADI M G D++D + G+F+ W+ + RKPVIAAV+G+ALGGGCELAMMCDFI Sbjct: 92 FAAGADIKEMQGLDFVDAYVGDFLG-GWDEVAATRKPVIAAVSGFALGGGCELAMMCDFI 150 Query: 121 IAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRI 180 IA+D AKFGQPEI LG++PG GG+QRL RAV KAKAMDL LTGRMMDA EAERAGLVSRI Sbjct: 151 IASDTAKFGQPEITLGVIPGMGGSQRLTRAVGKAKAMDLVLTGRMMDAAEAERAGLVSRI 210 Query: 181 VAADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQ 240 V A L+E A+ AA IA + R +M K+SVNR++E L+EG++YER F S FATEDQ Sbjct: 211 VPAADLMEVAVEAATRIASLSRASVLMAKESVNRSFEVPLAEGLRYERRAFQSLFATEDQ 270 Query: 241 KEGMKAFLEKRQPVFKH 257 KEGM AF+EKR+P F++ Sbjct: 271 KEGMAAFVEKRKPAFRN 287 >Rv1070c [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu Mycobacterium tuberculosis H37Rv Length = 257 Score = 324 bits (830), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 160/257 (62%), Positives = 190/257 (73%), Gaps = 1/257 (0%) Query: 1 MSYENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKA 60 M+YE I VE ++VG+I L+RP+ALNAL+ +M E+ A D +IG IIITGS KA Sbjct: 1 MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKA 60 Query: 61 FAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFI 120 FAAGADI MA + D F +F W L +R P IAAVAGYALGGGCELAMMCD + Sbjct: 61 FAAGADIKEMADLTFADAFTADFFA-TWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVL 119 Query: 121 IAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRI 180 IAAD AKFGQPEIKLG++PG GG+QRL RA+ KAKAMDL LTGR MDA EAER+GLVSR+ Sbjct: 120 IAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRV 179 Query: 181 VAADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQ 240 V AD LL EA A A I++M A M K++VNRA+E++LSEG+ YER LF+S FATEDQ Sbjct: 180 VPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQ 239 Query: 241 KEGMKAFLEKRQPVFKH 257 EGM AF+EKR P F H Sbjct: 240 SEGMAAFIEKRAPQFTH 256 >MT1100 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC Mycobacterium tuberculosis CDC1551 Length = 257 Score = 324 bits (830), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 160/257 (62%), Positives = 190/257 (73%), Gaps = 1/257 (0%) Query: 1 MSYENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKA 60 M+YE I VE ++VG+I L+RP+ALNAL+ +M E+ A D +IG IIITGS KA Sbjct: 1 MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKA 60 Query: 61 FAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFI 120 FAAGADI MA + D F +F W L +R P IAAVAGYALGGGCELAMMCD + Sbjct: 61 FAAGADIKEMADLTFADAFTADFFA-TWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVL 119 Query: 121 IAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRI 180 IAAD AKFGQPEIKLG++PG GG+QRL RA+ KAKAMDL LTGR MDA EAER+GLVSR+ Sbjct: 120 IAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRV 179 Query: 181 VAADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQ 240 V AD LL EA A A I++M A M K++VNRA+E++LSEG+ YER LF+S FATEDQ Sbjct: 180 VPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQ 239 Query: 241 KEGMKAFLEKRQPVFKH 257 EGM AF+EKR P F H Sbjct: 240 SEGMAAFIEKRAPQFTH 256 >ML2402 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mle Mycobacterium leprae Length = 257 Score = 312 bits (800), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 150/257 (58%), Positives = 190/257 (73%), Gaps = 1/257 (0%) Query: 1 MSYENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKA 60 M Y+ I V+ +++VG+I L+RP+ALNAL+ +M E+ A D ++G I+ITGS K Sbjct: 1 MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDIDPDVGAILITGSPKV 60 Query: 61 FAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFI 120 FAAGADI MA + D F +F + W L +R P+IAAVAGYALGGGCELAMMCD + Sbjct: 61 FAAGADIKEMASLTFTDAFDADFFS-AWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLL 119 Query: 121 IAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRI 180 IAAD AKFGQPEIKLG++PG GG+QRL RA+ KAKAMDL LTGR +DA EAER+GLVSR+ Sbjct: 120 IAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRV 179 Query: 181 VAADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQ 240 V AD LL EA A A I++M R M K++VNR++E+TL+EG+ +ER LF+S F T+DQ Sbjct: 180 VLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQ 239 Query: 241 KEGMKAFLEKRQPVFKH 257 EGM AF+EKR P F H Sbjct: 240 SEGMAAFIEKRAPQFTH 256 >mll5584 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mlo Mesorhizobium loti Length = 257 Score = 310 bits (793), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 162/257 (63%), Positives = 196/257 (76%), Gaps = 1/257 (0%) Query: 1 MSYENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKA 60 M+YE I ET KVGL+ L+RPKALNAL+ L+ EL A+ FDA IG ++ITGS+KA Sbjct: 1 MAYETIITETRGKVGLVTLNRPKALNALNLQLLAELVAAVKDFDADAGIGAVVITGSDKA 60 Query: 61 FAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFI 120 FAAGADI M + D + + WE L R+RKPVIAAVAGYALGGGCELAMMCDFI Sbjct: 61 FAAGADIKEMQAISFADAYLQDLFV-GWEDLTRVRKPVIAAVAGYALGGGCELAMMCDFI 119 Query: 121 IAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRI 180 IAAD AKFGQPEI LG++PG GG+QRL R V K+KAMD+ LTGRMMDA EAER+GLVSR+ Sbjct: 120 IAADTAKFGQPEITLGVIPGMGGSQRLTRFVGKSKAMDMCLTGRMMDAAEAERSGLVSRV 179 Query: 181 VAADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQ 240 V A +L+EEA+ AA IA+ MM K++VNR+YETTL+EG+++ER LF+S FA EDQ Sbjct: 180 VPAAELVEEAVKAAAKIADFSLPSVMMAKEAVNRSYETTLTEGLRFERRLFHSLFALEDQ 239 Query: 241 KEGMKAFLEKRQPVFKH 257 KEGM AF EKR+P F + Sbjct: 240 KEGMAAFAEKRKPNFAN 256 >CC0006 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ccr Caulobacter vibrioides Length = 262 Score = 285 bits (729), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 157/258 (60%), Positives = 191/258 (74%), Gaps = 5/258 (1%) Query: 3 YENIQVETHEK---VGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEK 59 ++ + VE E V LIRL+RP+ALNAL+ L+ EL +AL A A + +GCI++TGS K Sbjct: 4 FQTLIVEAPESAPGVTLIRLNRPEALNALNTALLGELAQALAAAQADDSVGCIVLTGSAK 63 Query: 60 AFAAGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDF 119 AFAAGADI M+ Y +FK +F T + + RKP+IAAVAGYALGGGCELAMMCDF Sbjct: 64 AFAAGADIKEMSDKTYAQMFKADFFTAGARAIEQCRKPIIAAVAGYALGGGCELAMMCDF 123 Query: 120 IIAADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSR 179 I+AAD AKFGQPEI LG+ PG GGTQRL R V K+KAMD+ LTGRMM AEEAER+GLVSR Sbjct: 124 ILAADTAKFGQPEINLGVAPGIGGTQRLTRFVGKSKAMDMILTGRMMGAEEAERSGLVSR 183 Query: 180 IVAADKLLEEAMA-AALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATE 238 I AD L++E +A AA I + P VAM K+ V AYETTL+ G+ ER LF+S FA E Sbjct: 184 IFPADSLVDETLAIAAKIAGQSPLAVAMN-KELVEAAYETTLTTGVALERRLFHSLFAFE 242 Query: 239 DQKEGMKAFLEKRQPVFK 256 DQKEGM AF+EKR+P+FK Sbjct: 243 DQKEGMTAFVEKRKPLFK 260 >SSO2624 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 266 Score = 243 bits (621), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 121/256 (47%), Positives = 177/256 (69%), Gaps = 1/256 (0%) Query: 3 YENIQVETHEKVGLIRLHRPKALNALSDGLMTELGEALLAFDAQEEIGCIIITGSEKAFA 62 Y IQ+E + +G+I+L+RP LNA++ ++ EL + L D ++I +IITG+ KAF+ Sbjct: 9 YSTIQIEVIDNIGIIKLNRPDKLNAINFQMVDELVDVLNKLDNDDKIKVVIITGNGKAFS 68 Query: 63 AGADISAMAGYDYMDVFKGEFITRNWETLRRIRKPVIAAVAGYALGGGCELAMMCDFIIA 122 AGAD+ M ++ K + WE LR +KPVIAA+ G GGG ELAM CD IIA Sbjct: 69 AGADVKEMLETPLEEIMKKGHMPL-WEKLRTFKKPVIAALNGITAGGGLELAMACDIIIA 127 Query: 123 ADNAKFGQPEIKLGIVPGAGGTQRLPRAVSKAKAMDLALTGRMMDAEEAERAGLVSRIVA 182 +++AK GQPEI LGI+PGAGGTQRL R + K KAM+L LTG+++D++EAER GLV+++V Sbjct: 128 SESAKLGQPEINLGIMPGAGGTQRLTRVLGKYKAMELVLTGKLIDSKEAERYGLVNKVVP 187 Query: 183 ADKLLEEAMAAALIIAEMPRQVAMMVKDSVNRAYETTLSEGMKYERALFYSCFATEDQKE 242 + L++EA+ A IAE P ++ K++V RA++T L +G+ +ER FY T++ KE Sbjct: 188 DNSLIDEAIRLAREIAEKPIISIILAKEAVARAWDTLLQQGLDFERRNFYLALNTKEAKE 247 Query: 243 GMKAFLEKRQPVFKHS 258 GM+AFLEKR+P +++ Sbjct: 248 GMRAFLEKRKPRWEND 263