BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0070.p (789 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3079 [R] COG1033 Predicted exporters of the RND superfamily Pa... 499 e-140 BB0252 Non COG 92 4e-18 Cj1373 [R] COG1033 Predicted exporters of the RND superfamily Cj... 73 3e-12 PAB1101 [R] COG1033 Predicted exporters of the RND superfamily P... 69 4e-11 AF0459 [R] COG1033 Predicted exporters of the RND superfamily Af... 67 2e-10 RSp1458 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 62 4e-09 MJ1562 [R] COG1033 Predicted exporters of the RND superfamily Mj... 62 7e-09 TP0790 [R] COG1033 Predicted exporters of the RND superfamily Tp... 62 8e-09 >PA3079 [R] COG1033 Predicted exporters of the RND superfamily Pae Pseudomonas aeruginosa Length = 793 Score = 499 bits (1284), Expect = e-140, Method: Compositional matrix adjust. Identities = 293/787 (37%), Positives = 450/787 (57%), Gaps = 18/787 (2%) Query: 13 LEASLFRLRIPILALLLAFTAVLSYFALQLRMDAGFEKQMPTHHEYIDTFKQYRDDVLG- 71 LE +F R ++ L + + L Y A Q+R FEK +P H +I ++R+D+ Sbjct: 15 LERLIFNNRPVVIFLCVLVSVFLFYQATQVRPSTSFEKMIPLEHPFIQKMLEHRNDLANL 74 Query: 72 ANRLNIVLRARHGSIWTKEGLTRLSEMTQAVMFLPNISRLGVQSLWTPNTFVNEITEEGF 131 N + I + A +G I+TKE + L ++ V ++P + R G++SLW+P+ E+TEEGF Sbjct: 75 GNTVRISVEAVNGDIFTKEYMETLRQIHDEVFYIPGVDRSGLKSLWSPSVRWTEVTEEGF 134 Query: 132 RADPVIPGTVIPSALTPEIIEQIRNTAINGGFVGTLISRNQDSAMIVAEINEF--DAKGE 189 VIP T S P +E++RN + G +G L++ N S+++ + E + K + Sbjct: 135 AGGEVIPQTYDGS---PRALEELRNNVLKSGQIGRLVANNFKSSIVDVPLLEMYPNPKNQ 191 Query: 190 ----KVDYLAYNKLLND-LRAKYE--NADFEVQIIGFAKQIGDVADGAEGVVKFCIMALL 242 K+DY ++ L + +R KY+ N + +V I+GFAK++GD+ DG VV F + LL Sbjct: 192 SELIKLDYRQFSHELEEKIRDKYQLQNPNVKVHIVGFAKKVGDLIDGLVMVVGFFGICLL 251 Query: 243 LTAIAVYWYCRSLPFTLLPVACSLVSLVWQFGTLRLLGYGLDPLAVLVPFLVFAIGVSHG 302 +T + +YW+ + + T+ + +LV+++WQ G L L+G+GLDP ++LVPFL+FAIG+SHG Sbjct: 252 ITLVLLYWFTKCIRSTIAVLITTLVAVLWQLGLLNLVGFGLDPYSMLVPFLIFAIGISHG 311 Query: 303 VQQINTIVRGIASGQSCEAAARASFKGLLIPGVLALVTALVSFVTLVMIPIPMVRELAIT 362 VQ+IN I + + AAR +F+ L +PG++A++ V F+TL++I I ++RELAI Sbjct: 312 VQKINGIALQSSGADNALMAARLTFRQLFLPGMIAILADAVGFITLLVIDIGVIRELAIG 371 Query: 363 ASIGVGYKIITNLVMLPLAASLLKVGKTYADAAMRAQQARGRWLAVLSRSAQPRVARSIV 422 ASIGV + TNL++LP+A S + + K + + +LS + P+VA + Sbjct: 372 ASIGVAVIVFTNLILLPVAISYIGISKKAVQRSKDDAVREHPFWRLLSNFSSPKVAPVSI 431 Query: 423 VITLLVLAGSAWYSHDRLVGTLQPGAPELHADARYNRDARWIADNYGNGLDWLTVILATP 482 I LL+L G WY +G L GAPEL D+RYN D +I NY D L V++ T Sbjct: 432 AIALLMLGGGLWYGKHLKIGDLDQGAPELRPDSRYNLDNDFIIRNYSTSSDVLVVMVKTS 491 Query: 483 ANSCDQVRFGRYQDQFDTVMRHVPGVLSVSSFADQMKIYNEGYNEGNPAMFTVPLDAGNY 542 C + D+ + + GV S S K +G NEGN T+ + N Sbjct: 492 PEGCSTHQALAAMDELAWKLENTEGVQSAISMVTVSKQVIKGMNEGNLKWETL---SRNQ 548 Query: 543 AALAVEIGRVRGFLSKDCNMLASHLFLADHKAATINGVIQAVKRYRDQHKLEGLEIRLAA 602 L I R G + DC++ +FL DHKA T++ + AV+ + ++ + L+ +LAA Sbjct: 549 DVLNNSIARADGLYNTDCSLAPLLVFLNDHKAETLDRAVAAVQAFAAENDKDDLQFQLAA 608 Query: 603 GNAGVIAAVNDEVEKSELPMMLYVYGAIVLLVFAVYRDWRAIIACCLPLTVATFIGYAFM 662 GNAG+ AA N+ +++SEL +++ VY + + +R + A + LPL + + +G A M Sbjct: 609 GNAGIEAATNEVIKQSELIILVLVYICVAAMCMITFRSFAATLCIVLPLILTSVLGNALM 668 Query: 663 KQLQIGLTVATLPVMVLAVGIGVDYAFYIYNRLQLHLAAGLAIEEALHNAIQEVGIATIF 722 L IG+ VATLPV+ L VGIGVDY YIY RL+ L GL ++EA + ++ G A +F Sbjct: 669 AALGIGVKVATLPVIALGVGIGVDYGIYIYTRLESFLRMGLPLQEAYYETLRSTGKAVLF 728 Query: 723 TAITLAIGVATWSFSDLKFQADMGKLLAFMFLVNLIMAMTALPAFAVVLDKMFPRKSPIK 782 T + LAIGVATW FS +KFQADMG +L FM L N+ A+ LPA A L + P K + Sbjct: 729 TGLCLAIGVATWIFSAIKFQADMGLMLTFMLLWNMFGALWLLPALARFL--INPAKLQAR 786 Query: 783 LNSALAH 789 S AH Sbjct: 787 KASLFAH 793 >BB0252 Non COG Length = 767 Score = 92.0 bits (227), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 117/549 (21%), Positives = 228/549 (41%), Gaps = 58/549 (10%) Query: 239 MALLLTAIAVYWYCRSLPFTLLPVACSLVSLVWQFGTLRLLGYGLDPLAVLVPFLVFAIG 298 +A + I++Y ++L L+P+ +L+SL+W FG L+ + + L+ +IG Sbjct: 210 LATFVVIISLYLIIKNLIGALIPIFIALLSLIWTFGIKGLVQSPITVPETSMIVLLISIG 269 Query: 299 VSHGVQQINTIVRGIASGQSCEAAARASFKGLLIPGVLALVTALVSFVTLVMIPIPMVRE 358 ++ V IN I + I Q + + +A+ K L P +L T F++L I + Sbjct: 270 CANAVHIINEIFKLIKKEQLSKESIKATIKKLKTPILLTSFTTAFGFLSLTTSSINAYKT 329 Query: 359 LAITASIGVGYKIITNLVMLPLAASLLKVGKTYADAAMRAQQARGRWLAVLSRSAQ--PR 416 + I SIGV +I +L +LP +L+ K + + + ++ L R A+ + Sbjct: 330 MGIFMSIGVIISMIISLTVLPGIITLIPFAKKKSFEKEKENKLNK--ISFLERLAKLNTQ 387 Query: 417 VARSIV------VITLLVLAGSAWYSHDRLVGTLQPGAPELHADAR-YNRDARWIADNYG 469 + +SI+ I +L++ G ++ VG L+ E++ D + Y +++ + Sbjct: 388 ITKSILKRKYTSSIMVLIILGISF------VGLLKI---EINFDEKDYFKESTSVKKTLN 438 Query: 470 ------NGLDWLTVILATPANSCDQVRFGRYQDQFDTVMRHVPGVLSVSSFADQMKIYNE 523 G+ + + + + D + SS +K N Sbjct: 439 LMQKEMGGISIFKIEIEGRPGEFKNAKAMQILDLITDKLDAFSAKTQSSSINGILKFTNF 498 Query: 524 GYNEGNPAMFTVPLDAGNYAALAVEIGRVRGFLSKDCNMLASHLFLADHKAATIN---GV 580 + +P + +P + + L+K N++ + D+K IN + Sbjct: 499 KIKKESPLEYKLPEN--------------KIILNKLINLIDKSDWTKDNKRMYINDDWSL 544 Query: 581 IQAVKRYRDQ-----HKLEGLEI----RLAAGNAGVIAAVNDEV------EKSELPMMLY 625 I + R D K E I N + V D+V K ++ ++ Sbjct: 545 ISIIVRIEDNSTEGIKKFEKYAINTINEYMKNNKYHFSGVYDKVLIAKTMVKEQVINIIT 604 Query: 626 VYGAIVLLVFAVYRDWRAIIACCLPLTVATFIGYAFMKQLQIGLTVATLPVMVLAVGIGV 685 G+I LL+ ++ + I +P+ + F+ +A M+ I L AT + +++G+GV Sbjct: 605 TLGSITLLLMFFFKSIKTGIIIAIPVAWSVFLNFAVMRLFGITLNPATATIASVSMGVGV 664 Query: 686 DYAFYIYNRLQLHLAAGLAIEEALHNAIQEVGIATIFTAITLAIGVATWSFSDLKFQADM 745 DY+ + +N L + AL +I V +I++ IG T +FS K + + Sbjct: 665 DYSIHFFNTFILQYQKNQIYKTALLESIPNVFNGIFANSISVGIGFLTLTFSSYKIISTL 724 Query: 746 GKLLAFMFL 754 G ++AF L Sbjct: 725 GAIIAFTML 733 >Cj1373 [R] COG1033 Predicted exporters of the RND superfamily Cje Campylobacter jejuni Length = 823 Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 172/789 (21%), Positives = 312/789 (39%), Gaps = 140/789 (17%) Query: 35 LSYFALQLRMDAGFEKQMPTHHEYIDTFKQYRDDVLGANRLNIVLRARHGSIWTKEGLTR 94 LS+FA +L +DA E + + TF++ N L + + ++ E L + Sbjct: 27 LSFFAFKLSVDASAESLLLEDDADLKTFREISKHYKSDNFLLLAFKPYDEKPFSNENLAK 86 Query: 95 LSEMTQAVMFLPNISRL---------------GVQSLWT--PN---------TFVNEITE 128 L ++ + + P + R+ ++ L PN NEI Sbjct: 87 LKKLHEELEKAPLVERVFSIINAPLLQSSQNTDLKELLKNIPNIESQDINRTKAQNEILN 146 Query: 129 EGFRADPVIP------GTVI---PSALTPEIIEQIRNTAINGGFVGTLISRNQDSAMIVA 179 F + +I G +I P + +IE+ R+ A + ++ I Sbjct: 147 SPFYKNNIISKDGKVTGLIIYLKPDTVYNNLIEK-RDLA----------TDEKEKDQIRL 195 Query: 180 EINEFDAKGEKVDYLAYNKLLNDLRAKYENADFEVQIIGFAKQIGD--VADGAEGVVKFC 237 I E K + + + + + + +R +N D +G I D +A +V + Sbjct: 196 AIKEHQDKQKVITKQSLDTIKSIVRNYEKNKD--TLYLGGVSMIADDMIAYIKSDLVLYG 253 Query: 238 IMALLLTAIAVYWYCRSLPFTLLPVACSLVSLVWQFGTLRLLGYGLDPLAVLVPFLVFAI 297 + + L +A+Y++ RS F LP+ +SL G LL + + ++ LV I Sbjct: 254 VSLVFLLGLALYYFFRSWRFVFLPLFICFISLSAASGVFALLNFQITVISSNYVALVLII 313 Query: 298 GVSHGVQQINTIVRGIASGQSCEAAARASFKGLLI---PGVLALVTALVSFVTLVMIPIP 354 +S V I + + + R + LL P + A+VT ++ F +L++ I Sbjct: 314 TLSVVVHLITHFIESTQNHPKAKVE-RIVLETLLAKANPSLYAIVTTMIGFFSLILSNIE 372 Query: 355 MVRELAITASIGVGYKIITNLVMLPLAASLLKVGKTYADAAMRAQQARGRWLAVLSRSA- 413 + +L I SIG+G +I + + L LLK K Y ++ + LA +++A Sbjct: 373 PIIKLGIMMSIGIGLALIFSYLFLASILVLLK-PKNY-----HKKEFKFNLLAFCAKTAL 426 Query: 414 QPRVAR-----SIVVITLLVLAGSAWYSHDRLVGTLQPGAPELHADARYNRDARWIADNY 468 P+ R S++ I L ++ S + V + G+ + I N Sbjct: 427 DPKKRRMIYEISVLAIILALIGISKLRVENSFVNYFKDGS-------EIKKGLLVIDKNL 479 Query: 469 GNGLDWLTVILATPANSCDQ----------------------------VRFGRYQDQFDT 500 G L L VI+ P N DQ R + +F Sbjct: 480 GGTLP-LEVIIRFPNNKNDQNASDTLDSFESEFENLATQETYWFDSKKTRIAKKVHEFLE 538 Query: 501 VMRHVPGVLSVSSFADQMKIYNEG----------YNEGNPAMFTVPLDAGNYAALAVEIG 550 V VLS++S K N+G NE PA F L + + E+ Sbjct: 539 NKEFVGSVLSLNSLLTLGKNINDGKELDDFALAFLNENLPAKFKQDLLSPFVSIENNELR 598 Query: 551 RVRGFLSKDCNMLASHLFLADHKAATINGVIQAVKRYRDQHKLEGLEIRLAAGNAGVIAA 610 + D N L + FL D K K+ + K +G+E+++ G++ Sbjct: 599 FSMRIVDSDPN-LRRNEFLIDLK-----------KQLNELVKNDGVEVQIT----GIMVL 642 Query: 611 VNDEVEK---SELPMMLYVYGAIVLLVFAVYRDWR----AIIACCLPLTVATFIGYAFMK 663 N+ ++ S+ +++V AI +L V+RD + AI+ +PL+V +A M Sbjct: 643 YNNMLQSLFSSQFDTLIFVILAIFILFIIVFRDLKFSVAAILVNVIPLSVV----FALMG 698 Query: 664 QLQIGLTVATLPVMVLAVGIGVDYAFYIYNRLQLHLAAGLAIEEALHNAIQEVGIATIFT 723 L I L + ++ + +A+GIGVD A + R + + ++EEA+ + +G A +T Sbjct: 699 LLGIPLDMMSITIAAIAIGIGVDDAIHYIYRFREEIKNK-SLEEAIMISHLSIGSALYYT 757 Query: 724 AITLAIGVA 732 I++ +G + Sbjct: 758 TISIVLGFS 766 >PAB1101 [R] COG1033 Predicted exporters of the RND superfamily Pab Pyrococcus abyssi Length = 746 Score = 68.9 bits (167), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 173/798 (21%), Positives = 328/798 (41%), Gaps = 118/798 (14%) Query: 25 LALLLAFTAVLSYFAL-QLRMDAGFEKQMPTHHEYIDTFKQYRDDVLGANRLNIVLRARH 83 LA++ F +LS + + QLR + KQ+P E + ++ +++ G+ I ++ ++ Sbjct: 16 LAVVTMFLLILSAYGITQLRFETDLSKQLPEDLEAVKSYFTLQNEFGGSGSALIYVKIKN 75 Query: 84 G-------------SIWTKEGLTRLSEMTQAVMFLPNISRLGVQSLWTPNTFVNEITEEG 130 ++++ E R E +I+ L VQ L ++E+ Sbjct: 76 NDNVVDIRDPKIIEAMYSLEQRLREKEYVTDTF---SIADLMVQILGRLPKNMDEVK--- 129 Query: 131 FRADPVIPGTVIPSALTPEIIEQIRNTAINGGFVGTLISRNQDSAMIVAEINEFDAKGEK 190 + + L PE A NG LIS + S +I+ +N K +K Sbjct: 130 ----------FVLNMLPPE--------ARNG-----LISGDYSSTIIIVNLNR--EKNQK 164 Query: 191 VDYLAYNKLLNDLRAKYENADF----EVQIIGFAKQIGDVADGAEGVVK--FCIMALLLT 244 A ++ ND+ + E +F EV + G + + + + I +++ Sbjct: 165 ----ALVRVYNDIEREIERTNFPQGVEVVLTGDLGITYKILEMLQNDMNRTMAISGIIVV 220 Query: 245 AIAVYWYCRSLPFTLLPVACSLVSLVWQFGTLRLLGYGLDPLAVLVPFLVFAIGVSHGVQ 304 I +Y+Y +S L+P+ + +V G + LLG LD V ++ +G+ +GV Sbjct: 221 LILLYFY-KSPIRMLVPLVPLIFGVVMTLGFMGLLGIPLDIATTTVGAMIIGMGIDYGVH 279 Query: 305 QINTIVRGIASGQSCEAAARASFKGLLIPGVLALVTALVSFVTLVMIPIPMVRELAITAS 364 N G+S E AA + + A +T + F+ L + +P ++ L+++ Sbjct: 280 VTNRYYEERGKGKSLEEAAEEAIAETGKALLGAALTTIAGFLALSISILPSLKRLSVSLV 339 Query: 365 IGVGYKIITNLVMLPLAASLL-----KVGKTYADAAMRAQQARGRWLAVLSRSAQPRVAR 419 +G+G + +++ P A L KV K A+ +++ ++ + A R Sbjct: 340 MGLGLAALNAVIVTPALAILEEEFREKVMKKKEIIAIGGGKSKISFIFSMLGKAIKRSPW 399 Query: 420 SIVVITLLVLAGSAWY------SHDRLVGTLQPGAPELHADARYNRDARWIADNYGNGLD 473 + ++I L++ +G + Y + RL + PE+ A + I +G G D Sbjct: 400 TALLIALII-SGVSLYGASKITTEVRLEKMIPTDLPEIQALSD-------IRSEFG-GQD 450 Query: 474 WLTVILAT-----PANSCDQVRFGRYQDQFDTVMRHVPGVLSVSSFADQMKIYNEGY--- 525 +T+++ P D +RF R + + D+ ++ V S AD + I GY Sbjct: 451 EVTILIKADDVRDPTLVRDILRFER-EIKADS---YINNVFETQSIADVV-IQKYGYIPQ 505 Query: 526 --NEGNPAMFTVPLDAGNYAALAVEI-GRVRGFLSKDCNMLASHLFLADHKAATINGVIQ 582 + + A+ L + +Y+ +++ G G + N + + A +A GV Sbjct: 506 DKEKISEAIEGSSLVSSDYSMTIIKLKGNFMGVTQSEFNRIMEYFERAIQRADFPPGV-- 563 Query: 583 AVKRYRDQHKLEGLEIRLAAGNAGVIAAVNDEVEKSELPMMLYVYGAIVLLVFAVYRDWR 642 K+E AG + + +ND V + + +V++VFA++R Sbjct: 564 ---------KVE------LAGESYLNYVLNDLVNEELGKISTIGTLIVVMVVFAIFRRPT 608 Query: 643 AIIACCLPLTVATF--IGYAFMKQLQIGLTVATLPVMVLAVGIGVDYAFYIYNRLQLHLA 700 IA +P+ + IGY + + T+A + M+ VG+GVDY +I +R L Sbjct: 609 VSIAMIMPMFLGALWTIGYMGLAGIPFSQTLAGVVSMI--VGLGVDYGMHITHRFLEELN 666 Query: 701 AGLAIEEALHNAIQEVGIATIFTAITLAIGVATWSFSDLKFQADMGKLLAFMFLVNLIMA 760 G + + A++ VG A+T A G + L D G++LA ++ A Sbjct: 667 EG--NKTPIITALESVGPGIFVGALTTAGGFLALLSAQLTAIHDFGRVLAVGIFASMFAA 724 Query: 761 MTALPAFAVVLDKMFPRK 778 PA +L F RK Sbjct: 725 YLVTPA---ILQLEFGRK 739 >AF0459 [R] COG1033 Predicted exporters of the RND superfamily Afu Archaeoglobus fulgidus Length = 736 Score = 66.6 bits (161), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 120/576 (20%), Positives = 239/576 (41%), Gaps = 42/576 (7%) Query: 214 VQIIGFAKQIGDVADGAEGVV--KFCIMALLLTAIAVYWYC---RSLPFTLLPVACSLVS 268 V + G A + +A E V F I ++ + A+ V + RS L P+ SL+S Sbjct: 187 VDVTGGAVLMYQIAKAVEEDVYRTFFIASVTMIAVLVAVFSGVVRSKLTVLFPLIVSLMS 246 Query: 269 LVWQFGTLRLLGYGLDPL-AVLVPFLVFAIGVSHGVQQINTIVRGIASGQSCEAAARASF 327 + G L LLG + + +P L+ + + + Q N G+ + A + Sbjct: 247 VAVMAGLLPLLGLQMTEYNSATIPILI-GLAIDYAAQLQNRYEEERRGGREVDEALEEAL 305 Query: 328 KGLLIPGVLALVTALVSFVTLVMIPIPMVRELAITASIGVGYKIITNLVMLPLAASLLKV 387 P +A+ T ++ F ++ IP + + S+G+ + + LP SLLK+ Sbjct: 306 NHTRFPLFMAMATTVIGFASMCAPGIPSLFWFSFLLSVGLITAFLLSNTFLP---SLLKL 362 Query: 388 GKTYADAAMRAQQ-ARGRWLAVLSRSAQPRVA--RSIVVITL-LVLAGSAWYSHDRLVGT 443 +D R + + G +L+ A+ +A R I+ +TL L++ G+ +H L Sbjct: 363 ----SDRGGREESISPGILEKLLTTIAKVTIANSRKILALTLILIVVGAYASTHVELETN 418 Query: 444 LQPGA-PELHADARYNRDARWIADNYGNGLDWLTVILATPANSCDQVRFGRYQDQFDTVM 502 + A P+L A ++ R ++ Y L +L+T + V + + + Sbjct: 419 RRKYAPPDLPALVKFEEIERKVSPQYVYAL-----VLSTERIDAESVV------KAEELA 467 Query: 503 RHVPGVLSVSSFADQMKIYNEGYNEGNPAMFTVPLDAGNYAALAVEIGRVRGFLSKDCNM 562 +++ + + K E Y +P ++ + A A+ F+S N Sbjct: 468 KYISSREEIYDYDSLGKTLEEYYG-------AIPAESFSKAIDALPKSIYSRFIS--GNQ 518 Query: 563 LASHLFLADHKAATINGVIQAVKRYRDQHKLEGLEIRLAAGNAGVIAAVNDEVEKSELPM 622 LA + + + ++++++ D LE G ++ +++ + S M Sbjct: 519 LAVYFYTNTQTEEEVEKMMRSIE--NDLRFLEWDGDYYITGFPVILGHLSEVLFSSLNLM 576 Query: 623 MLYVYGAIVLLVFAVYRDWRAIIACCLPLTVATFIGYAFMKQLQIGLTVATLPVMVLAVG 682 L Y IV + YR I + ++VA M + I T ++ + + +G Sbjct: 577 TLVAYLLIVTFLLLAYRSVVRAIIPLISISVAVASMNVCMLLMGIKQTTISIALNSIVLG 636 Query: 683 IGVDYAFYIYNRLQLHLAAGLAIEEALHNAIQEVGIATIFTAITLAIGVATWSFSDLKFQ 742 +G+DY+ +I R +EE++ ++ G A + +A+T A G FS Sbjct: 637 MGIDYSIHITER-YFEERGKFGVEESVKRTVERTGKAVLTSALTTAGGFGALYFSTFPVL 695 Query: 743 ADMGKLLAFMFLVNLIMAMTALPAFAVVLDKMFPRK 778 ++ G L + +L+ A +A+PA ++ +K + R+ Sbjct: 696 SNFGILAFIAIIFSLLAATSAVPALLILYEKNYFRE 731 >RSp1458 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1034 Score = 62.4 bits (150), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 54/201 (26%), Positives = 98/201 (48%), Gaps = 6/201 (2%) Query: 199 LLNDLR---AKYENADFEVQIIGFAKQIGDVADGAEGVVKFCIMALLLTAIAVYWYCRSL 255 +L+D+R A + + EV++ + + + D EG + I LL V+W+ R Sbjct: 295 VLHDVRKAIATFAESHPEVRLAEASNTVSPIEDNYEGSMSMLIEGALLAIAVVWWFLRDG 354 Query: 256 PFTLLPVACSLVSLVWQFGTLRLLGYGLDPLAVLVPFLVFAIGVSHGVQQINTIVRGIAS 315 TL+ A +S++ FG + L GY L+ + +L LV I V + +I I R + Sbjct: 355 RATLVSAAALPLSIIPTFGAIYLAGYSLNTITLLALSLVVGILVDDAIVEIENIERHLRM 414 Query: 316 GQSC-EAAARASFK-GL-LIPGVLALVTALVSFVTLVMIPIPMVRELAITASIGVGYKII 372 G++ +AA A+ + GL +I ALV + + IP + R+ +TAS+ V ++ Sbjct: 415 GKTPYQAAMEAADEIGLAVIATTFALVAVFLPTAFMSGIPGLIFRQFGVTASVAVLMSLL 474 Query: 373 TNLVMLPLAASLLKVGKTYAD 393 ++ P+ A+ L +A+ Sbjct: 475 VARLLTPMMAAYLMKATRHAE 495 >MJ1562 [R] COG1033 Predicted exporters of the RND superfamily Mja Methanococcus jannaschii Length = 388 Score = 61.6 bits (148), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 78/334 (23%), Positives = 144/334 (43%), Gaps = 48/334 (14%) Query: 464 IADNYGNGLDWLTVILA-TPANSCDQV------RFGRYQDQFDTVMRHVPGVLSVSSFAD 516 + D +G G D +T+ + P++S D+V R + + + +R+V G+ SVSS D Sbjct: 65 VRDEFG-GTDVITICIKLKPSDSSDKVVDIRDPRVLKAIKELEDNLRYVDGITSVSSPVD 123 Query: 517 QMKIYNEGYNEGNPAMFTVPLDAGNYAALAVEIGRVRGFLSKDCNMLASHLFLADHKAAT 576 + N G VP D I V+ L+K +F +D+ Sbjct: 124 IIIQKNNGI---------VPND----------IDTVKDILNKLPEDKRKRIFNSDYSMTV 164 Query: 577 INGVIQAVKRYRDQHKL-----------------EGLEIRLAAGNAGVIAAVNDEVEKSE 619 +N A DQ KL G+E+ +A G + +++ +++S+ Sbjct: 165 VNAYTDA---GGDQKKLMRVMDDVNERIEETPFPPGVEV-IATGTPPMRKLMDELMKESQ 220 Query: 620 LPMMLYVYGAIVLLVFAVYRDWRAIIACCLPLTVATFIGYAFMKQLQIGLTVATLPVMVL 679 I++++ +R + I LP+ +A M L I L +AT + L Sbjct: 221 SFTTTVGLIGILIILIIYFRKPLSSIMPLLPVLIAVIWTGGAMGLLDIPLDMATAGIGSL 280 Query: 680 AVGIGVDYAFYIYNRLQLHLAAGLAIEEALHNAIQEVGIATIFTAITLAIGVATWSFSDL 739 +G+G+DY ++ +R G+ I++A+ A+ E G A + T T +G + L Sbjct: 281 ILGLGIDYGIHLMHRYDEERRKGMPIDKAIETAVVETGTAVMATTATTVVGFLALVLAPL 340 Query: 740 KFQADMGKLLAFMFLVNLIMAMTALPAFAVVLDK 773 A++GK+ A +++ +T LPA V+ ++ Sbjct: 341 PMMANLGKVCALGISFCMVVVLTLLPALIVIEER 374 >TP0790 [R] COG1033 Predicted exporters of the RND superfamily Tpa Treponema pallidum Length = 888 Score = 61.6 bits (148), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 50/200 (25%), Positives = 89/200 (44%), Gaps = 8/200 (4%) Query: 579 GVIQAVKRYRDQHKLEGLEIRLAAGNAGVIAAVNDEVEKSELPMMLYVYGAIVLLVFAVY 638 GVI+AVK++ ++ + + G+ V ++ND V +S+L +++ + +++ Y Sbjct: 691 GVIEAVKKFIRENFPQDVHAEFG-GSVLVEQSLNDLVVQSQLISLVFSLCVVFIIIAVHY 749 Query: 639 RDWRAIIACCLPLTVATFIGYAFMKQLQIGLTVATLPVMVLAVGIGVDYAFYI---YNRL 695 R A I LPL V+ + + M I L + T V + GIGVDY + Y R Sbjct: 750 RSLFAGIIGTLPLGVSVLVNFGVMGFFGIKLNICTTMVAGFSSGIGVDYTIHYLAAYRRA 809 Query: 696 QLHLAAGLAIEEALHNAIQEVGIATIFTAITLAIGVATWSFSDLKFQADMGKLLAFMFLV 755 + + + + G A +F +++ G A S AD G L+ L Sbjct: 810 WKECGGKDFLTQTFYGS----GRAILFNVLSVGSGFAVLMLSKFNVLADFGLLMVLAMLT 865 Query: 756 NLIMAMTALPAFAVVLDKMF 775 + + ++T LP V+ F Sbjct: 866 SSVASLTLLPTLLNVVKPRF 885