BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0068.p (476 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0141 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme ... 294 4e-79 FN0454 [C] COG1012 NAD-dependent aldehyde dehydrogenases Fnu Fus... 290 3e-78 MA4079 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mac Met... 290 7e-78 feaB [C] COG1012 NAD-dependent aldehyde dehydrogenases Eco Esche... 282 1e-75 STM3129 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sty Sa... 272 1e-72 BS_dhaS [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Ba... 271 3e-72 CC3140 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Cau... 270 4e-72 STM1597 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sty Sa... 268 2e-71 mlr5385 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Me... 267 4e-71 PA0265 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 263 1e-69 >BMEII0141 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme Brucella melitensis Length = 271 Score = 294 bits (752), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 145/270 (53%), Positives = 184/270 (68%) Query: 126 EVVFEDETRRDELHRKPYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSVCG 185 EVV +D R E+HRKP GV +I PWNWP+MI+ W +IPA+ GNTVV+KPS T + Sbjct: 2 EVVQDDNEGRVEIHRKPIGVTGSITPWNWPVMIACWHIIPAVRTGNTVVIKPSPLTPLST 61 Query: 186 LELARVVADALPPGVLNTVSGDGSVGAMLVEDGDVNKIMFTGSGATGARIVAAAARNLTP 245 + L ++ + LP GV+N V+G+ S+GA L + K+ FTGS TG +I+A+AA L Sbjct: 62 IRLVEIINEVLPAGVVNVVTGENSIGAALSAHPGIAKMTFTGSTETGRKIMASAAATLKR 121 Query: 246 TTMELGGNDAAIVLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDELKA 305 T+ELGGNDA IVL DADP IA GLFWGAF+N GQTCA KRLYV D ++D + L Sbjct: 122 LTLELGGNDAGIVLPDADPARIAEGLFWGAFINSGQTCAALKRLYVHDHIYDDVCRHLTE 181 Query: 306 IIAALPMGDGLQPGIAMGPVQNPMQLKKVVALVESAREEGGTIVCGGVLPDGPGNFYPLT 365 A + +GDGL +G VQN MQ KV LV+ AR +G I+ GG +GPG FYP+T Sbjct: 182 YAANIIIGDGLDEKSVLGLVQNAMQFNKVRELVDDARAKGARILIGGEAAEGPGYFYPIT 241 Query: 366 LVTGLRDGARLVDEEQFGPVLPIIRYSDLE 395 LV + +G RLVDEEQFGPVLPIIRYSD++ Sbjct: 242 LVADIDNGTRLVDEEQFGPVLPIIRYSDID 271 >FN0454 [C] COG1012 NAD-dependent aldehyde dehydrogenases Fnu Fusobacterium nucleatum Length = 491 Score = 290 bits (743), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 162/460 (35%), Positives = 253/460 (55%), Gaps = 16/460 (3%) Query: 21 SHNPATGAVMGRFPQSDAIEVAAAVAAARQAQPAWAALSLVQRREYLNRVADAIAANAER 80 S+ P ++ FP + ++ A+ +A++A W ++ +R LN++AD I N + Sbjct: 28 SYAPYNNELLSEFPDASESDIDFAIKSAKEAFKTWRKTTVKERARILNKIADIIDENKDL 87 Query: 81 LATLVTQEQGRPLGGVGPGQVP--GSRFELW-GCEAWTRATASLELAPEVVFEDETRRDE 137 LAT+ T + G+P+ +P + F + GC A++ DE Sbjct: 88 LATVETMDNGKPIRETKLVDIPLAATHFRYFAGCILADEGQATVL--------DEKFLSL 139 Query: 138 LHRKPYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSVCGLELARVVADALP 197 + R+P GV+ I PWN+P +++ W++ PAL AG+TVVLKPS T++ L L ++ D +P Sbjct: 140 ILREPIGVVGQIIPWNFPFLMAAWKLAPALAAGDTVVLKPSSTTTLSLLVLMELIQDVIP 199 Query: 198 PGVLNTVSGDGSV-GAMLVEDGDVNKIMFTGSGATGARIVAAAARNLTPTTMELGGNDAA 256 GV+N V+G GS G L D++K+ FTGS A G I AAA L P T+ELGG A Sbjct: 200 KGVVNLVTGKGSTAGEFLKNHPDLDKLAFTGSTAVGRDIALAAAEKLIPATLELGGKSAN 259 Query: 257 IVLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDELKAIIAALPMGDGL 316 I+LDDAD + G G N GQ C R++V + ++D+ + +L + +G+ L Sbjct: 260 IILDDADIEKALEGAQLGILFNQGQVCCAGSRIFVQEGIYDEFISKLVKKFENIKIGNPL 319 Query: 317 QPGIAMGPVQNPMQLKKVVALVESAREEGGTIVCGGV--LPDG--PGNFYPLTLVTGLRD 372 P MG + Q+K ++ VE A++EGG I+ GGV +G GNF TL+T + + Sbjct: 320 DPTTIMGSQIDARQVKTILDYVEIAKQEGGVILTGGVKYTENGCDKGNFVRPTLITNVNN 379 Query: 373 GARLVDEEQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRAAQVATRLQAGTV 432 G R+ EE FGPV +I++ ++ IA AN + GLG +V++ + RA ++A +Q G V Sbjct: 380 GCRVSQEEIFGPVAVVIKFKTDDEVIAQANDSEYGLGGAVFTKNINRALKLAREIQTGRV 439 Query: 433 WVNQHGMVHPMVPFGGNKRSGWGVEFGQEGLKGVTQPQVI 472 W+N + + PFGG K+SG G E + L+ TQ + I Sbjct: 440 WINTYNQIPEHAPFGGYKKSGIGRETHKVILEHYTQMKNI 479 >MA4079 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mac Methanosarcina acetivorans str.C2A Length = 479 Score = 290 bits (741), Expect = 7e-78, Method: Compositional matrix adjust. Identities = 182/463 (39%), Positives = 260/463 (56%), Gaps = 17/463 (3%) Query: 22 HNPATGAVMGRFPQSDAIEVAAAVAAARQAQPAWAALSLVQRREYLNRVADAIAANAERL 81 NPATG ++ + P+ +VA AV AA A WA+ S QR E L R A+ + + L Sbjct: 24 KNPATGELIEQVPRGTEEDVAVAVEAASSAFTGWASASPQQRGEVLYRAAEIVRQRKDEL 83 Query: 82 ATLVTQEQGRPLGGVGPGQVPGSRFELWGCEAWTRATASLELAPEVVFEDETRRDELH-- 139 A+L+TQEQG+P + +R E+ G L + F Sbjct: 84 ASLLTQEQGKP--------IVEARNEIEGFAHVLEYYCGLSGSQRGDFIPVPGNGYAFTV 135 Query: 140 RKPYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSVCGLELARVVADA-LPP 198 +KP GV AAI PWN P +I W++ P L +GNT+VLKP+ T + L LA + +A LP Sbjct: 136 KKPLGVCAAIIPWNMPALIMGWKIAPVLISGNTLVLKPASNTPLTNLTLASIFVEAGLPA 195 Query: 199 GVLNTVSGDG-SVGAMLVEDGDVNKIMFTGSGATGARIVAAAARNLTPTTMELGGNDAAI 257 GVLN V+G G +VG LV +V KI FTG TG R+ AA + T+ELGG+D + Sbjct: 196 GVLNVVTGPGETVGESLVRSPEVRKISFTGEARTGKRVAELAACGMKRITLELGGSDPML 255 Query: 258 VLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDELKAIIAALPMGDGLQ 317 V DDAD ++ A G G F N GQTC KRLYV +++ ++ + +L+ I +L +G+G+ Sbjct: 256 VCDDADLESAAAGALRGRFYNCGQTCTAVKRLYVFESVAEEFIKKLETGIKSLRLGNGMD 315 Query: 318 PGIAMGPVQNPMQLKKVVALV-ESAREEGGTIVCGGVLPD----GPGNFYPLTLVTGLRD 372 I+MGP+ N Q + + L E ++ G I+ GG +P+ G F+ TLV+ + Sbjct: 316 KNISMGPLNNRTQWEYIKELAAEIEEKDAGRIITGGKVPEFKDSEKGYFFEPTLVSDVPG 375 Query: 373 GARLVDEEQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRAAQVATRLQAGTV 432 +RL+ EE FGP+LP++ +L++AI AN GLGAS+W+ + RA + +L AG + Sbjct: 376 DSRLLKEEVFGPLLPVVTVKNLDEAIVGANSTCYGLGASIWTKNIDRARKGCEQLNAGII 435 Query: 433 WVNQHGMVHPMVPFGGNKRSGWGVEFGQEGLKGVTQPQVISLK 475 W+NQH V P VPFGG K SG+G E G E L + + I LK Sbjct: 436 WINQHLKVAPEVPFGGVKESGFGRENGPESLSEYLETKTIMLK 478 >feaB [C] COG1012 NAD-dependent aldehyde dehydrogenases Eco Escherichia coli K12 Length = 500 Score = 282 bits (722), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 176/465 (37%), Positives = 256/465 (55%), Gaps = 19/465 (4%) Query: 23 NPATGAVMGRFPQSDAIEVAAAVAAARQA--QPAWAALSLVQRREYLNRVADAIAANAER 80 +PATG + ++ +V AV +A +A WA +R L R AD + ++E Sbjct: 42 DPATGQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEE 101 Query: 81 LATLVTQEQGRPLGGVGPGQVPGSRFELWGCEAWTRATASLE-------LAPEVVFEDET 133 LA L T EQG+ + FE+ W R TA L L + Sbjct: 102 LAQLETLEQGKSIA-------ISRAFEVGCTLNWMRYTAGLTTKIAGKTLDLSIPLPQGA 154 Query: 134 RRDELHRK-PYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSVCGLELARVV 192 R RK P GV+A I PWN+PLMI +W+V+PAL AG ++V+KPSE T + L +A + Sbjct: 155 RYQAWTRKEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELA 214 Query: 193 ADA-LPPGVLNTVSGDGSV-GAMLVEDGDVNKIMFTGSGATGARIVAAAARNLTPTTMEL 250 ++A +P GV N V+G G+V GA L V KI FTGS ATG I AA +LT T+EL Sbjct: 215 SEAGIPDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLEL 274 Query: 251 GGNDAAIVLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDELKAIIAAL 310 GG + AIVL DADP+ + GL G+FLN GQ CA + R+Y+ L D +V + + +L Sbjct: 275 GGKNPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSL 334 Query: 311 PMGDGLQPGIAMGPVQNPMQLKKVVALVESAREEGGTIVCGGVLPDGPGNFYPLTLVTGL 370 +G G+ P + P+ + KV + ++ A+ + ++ G P G G + TLV Sbjct: 335 QVGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVNP 394 Query: 371 RDGARLVDEEQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRAAQVATRLQAG 430 RL EE FGPV+ ++R +D E+A+ AN + GL ASVW+ + +A + + RLQAG Sbjct: 395 DAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRLQAG 454 Query: 431 TVWVNQHGMVHPMVPFGGNKRSGWGVEFGQEGLKGVTQPQVISLK 475 TVWVN H ++ +PFGG K+SG G +FG + L G + + + ++ Sbjct: 455 TVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCVR 499 >STM3129 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sty Salmonella typhimurium LT2 Length = 494 Score = 272 bits (695), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 168/475 (35%), Positives = 251/475 (52%), Gaps = 9/475 (1%) Query: 10 GQLRAGSRQRDS------HNPATGAVMGRFPQSDAIEVAAAVAAARQAQPAWAALSLVQR 63 GQ AG RQ + NPATG ++ + + A+ +AR+A W + +QR Sbjct: 19 GQFIAGERQAGNGTNFSVTNPATGKIIADVVSATPAQAEEAMQSARRAFDVWRKMPTLQR 78 Query: 64 REYLNRVADAIAANAERLATLVTQEQGRPLGGVGPGQVPGSRFELWGCEAWTRATASLEL 123 L ++AD +AA+ E LA L + G+ + ++ S L W L Sbjct: 79 GALLLKLADTLAAHREELAQLESVCSGKTIMLSRGLELDQSVAFLRYFAGWAGKITGETL 138 Query: 124 APEVVFEDETRRDEL-HRKPYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTS 182 + E R R+P GV+ I PWN+ +MI+IW++ AL G T+V+KPSEYT Sbjct: 139 NVSLPSMGEERYTAFTQRQPIGVVVGIVPWNFSIMIAIWKLAAALVCGCTIVIKPSEYTP 198 Query: 183 VCGLELARVVADA-LPPGVLNTVSG-DGSVGAMLVEDGDVNKIMFTGSGATGARIVAAAA 240 + L +A + +A P GV+N V+G G + L+ D K+ FTGS ATG ++ +A Sbjct: 199 LTLLRVAELAKEAGFPDGVINVVNGAGGEIAQQLIAHPDCAKVSFTGSVATGEKVRRSAT 258 Query: 241 RNLTPTTMELGGNDAAIVLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIV 300 + T+ELGG +AA+ L+D +A+ G+ +LN GQ CA A+R Y+P D ++ Sbjct: 259 SSGKRVTLELGGKNAALFLNDLTAQAMVNGILEAGYLNQGQICAAAERFYLPQEKLDTVM 318 Query: 301 DELKAIIAALPMGDGLQPGIAMGPVQNPMQLKKVVALVESAREEGGTIVCGGVLPDGPGN 360 L+ ++ + G L MGP+ N +QL+KV+ L++ AREEG TIV GG G G Sbjct: 319 TLLRQRLSEIVPGSPLDEKTVMGPLANQVQLEKVLRLIQRAREEGDTIVYGGETLPGEGY 378 Query: 361 FYPLTLVTGLRDGARLVDEEQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRA 420 F T V + L+ EE FGPV I Y + ++A+++ N GL ASVWS + +A Sbjct: 379 FLQPTAVKVRSKNSTLMHEETFGPVCSFIGYQNEKEALSHINDSPFGLAASVWSENISKA 438 Query: 421 AQVATRLQAGTVWVNQHGMVHPMVPFGGNKRSGWGVEFGQEGLKGVTQPQVISLK 475 + A + AG VWVN H + P VPFGG K SG G EFG + T+ + + ++ Sbjct: 439 LRYAEDIDAGMVWVNMHTFLDPAVPFGGMKGSGIGREFGSAFIDDYTELKSVMVR 493 >BS_dhaS [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Bacillus subtilis Length = 495 Score = 271 bits (693), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 154/457 (33%), Positives = 240/457 (52%), Gaps = 9/457 (1%) Query: 20 DSHNPATGAVMGRFPQSDAIEVAAAVAAARQA--QPAWAALSLVQRREYLNRVADAIAAN 77 D+ NPATG + ++ A +V AV AAR+A Q W +S R + ++AD + + Sbjct: 38 DTPNPATGETLMTLYEAQAADVDKAVKAARKAFDQGEWRTMSPASRSRLMYKLADLMEEH 97 Query: 78 AERLATLVTQEQGRPLGGVGPGQVPGSRFELWGCEAWTRATASLELAPEVVFEDETRRDE 137 LA L T + G+P+ G +P + + W + + + TR + Sbjct: 98 KTELAQLETLDNGKPINETTNGDIPLAIEHMRYYAGWCTKITGQTIPVSGAYFNYTRHE- 156 Query: 138 LHRKPYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSVCGLELARVVADA-L 196 P GV+ I PWN+PL++++W++ AL G T+VLKP+E T + L LA ++ A Sbjct: 157 ----PVGVVGQIIPWNFPLLMAMWKMGAALATGCTIVLKPAEQTPLSALYLAELIDQAGF 212 Query: 197 PPGVLNTVSGDGS-VGAMLVEDGDVNKIMFTGSGATGARIVAAAARNLTPTTMELGGNDA 255 P GV+N + G G G L V+KI FTGS G +I++ AA+++ T+ELGG Sbjct: 213 PAGVINIIPGFGEDAGEALTNHEAVDKIAFTGSTEIGKKIMSTAAKSIKRVTLELGGKSP 272 Query: 256 AIVLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDELKAIIAALPMGDG 315 I+L DA+ K PG G N GQ C R+++ +D++VDE+ + +L G G Sbjct: 273 NILLPDANLKKAIPGALNGVMFNQGQVCCAGSRVFIHKDQYDEVVDEMASYAESLRQGAG 332 Query: 316 LQPGIAMGPVQNPMQLKKVVALVESAREEGGTIVCGGVLPDGPGNFYPLTLVTGLRDGAR 375 L +GP+ + Q ++V++ ++ ++EG V GG P G F T+ + D Sbjct: 333 LHKDTQIGPLVSKEQHERVLSYIQKGKDEGAKAVTGGSCPFEAGYFVAPTVFANVEDEMT 392 Query: 376 LVDEEQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRAAQVATRLQAGTVWVN 435 + EE FGPVL I Y +++ I AN + GL A +W+ + ++A +A RLQAGTVWVN Sbjct: 393 IAKEEIFGPVLTAIPYETVDEVIERANHSEYGLAAGLWTENVKQAHYIADRLQAGTVWVN 452 Query: 436 QHGMVHPMVPFGGNKRSGWGVEFGQEGLKGVTQPQVI 472 + + PFGG K+SG G E G L T+ + + Sbjct: 453 CYNVFDAASPFGGYKQSGLGREMGSYALDNYTEVKSV 489 >CC3140 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Caulobacter vibrioides Length = 482 Score = 270 bits (691), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 177/471 (37%), Positives = 245/471 (52%), Gaps = 8/471 (1%) Query: 7 IIGGQLRAGSRQRDSHNPATGAVMGRFPQSDAIEVAAAVAAARQAQPAWAALSLVQRREY 66 +I GQ G D NPA G ++ A E A+ AA +A PAWAA + +R Sbjct: 12 LIDGQWVRGEASFDVLNPADGTLIAAVADLGAAETTLAIDAAHRALPAWAARTAKERGAI 71 Query: 67 LNRVADAIAANAERLATLVTQEQGRPLGGVGPGQVPGSRFELWGCEAWTRATASLELAPE 126 L R +D I A+A+ LA L+T EQG+PL V G+ F W E RA P Sbjct: 72 LRRWSDLILAHADDLARLMTDEQGKPLAEAKGEVVYGASFIDWFAEEAKRAYGHTIPTPM 131 Query: 127 VVFEDETRRDELHRKPYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSVCGL 186 +R ++P GV AAIAPWN+P+ + +V PAL AG TVV+KP+ T + L Sbjct: 132 -----PGKRLASIKQPVGVCAAIAPWNFPIAMITRKVGPALAAGCTVVVKPAAETPLSAL 186 Query: 187 ELARVVADA-LPPGVLNTVSGDGS--VGAMLVEDGDVNKIMFTGSGATGARIVAAAARNL 243 +AR+ +A +P GVLN V+ S VG +L +D V K+ FTGS G + A + Sbjct: 187 AIARLATEAGVPAGVLNIVTTTRSSEVGKVLCDDSRVRKLSFTGSTPIGKVLYQQCAGTM 246 Query: 244 TPTTMELGGNDAAIVLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDEL 303 ++ELGGN IV DDAD +A G + N GQTC CA RL V +HD L Sbjct: 247 KKLSLELGGNAPFIVFDDADLEAAVDGAIASKYRNAGQTCVCANRLIVQSGIHDAFAARL 306 Query: 304 KAIIAALPMGDGLQPGIAMGPVQNPMQLKKVVALVESAREEGGTIVCGGVLPDGPGNFYP 363 +AAL +G G G+ +GP+ N L KVV LV A + G ++ GG + G+FY Sbjct: 307 AEKVAALKVGPGTGEGVQIGPLINEKALTKVVGLVSGAVQAGAEVLTGGDVHGLGGHFYQ 366 Query: 364 LTLVTGLRDGARLVDEEQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRAAQV 423 T++ G R+ EE FGPV PI+++ +A+ AN GL A +S D R +V Sbjct: 367 PTVLVGATPEMRIFQEEIFGPVAPIVKFETEAEAVELANATPFGLAAYFYSRDVGRCWRV 426 Query: 424 ATRLQAGTVWVNQHGMVHPMVPFGGNKRSGWGVEFGQEGLKGVTQPQVISL 474 A +++AG V +N+ + + PFGG K SG G E EGL + + + Sbjct: 427 AEQIEAGMVGINEGLISTEVAPFGGVKESGLGREGASEGLDEYLETKYLCF 477 >STM1597 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sty Salmonella typhimurium LT2 Length = 481 Score = 268 bits (686), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 175/475 (36%), Positives = 253/475 (53%), Gaps = 11/475 (2%) Query: 7 IIGGQLRAGSRQRDS-HNPATGAVMGRFPQSDAIEVAAAVAAARQAQPAWAALSLVQRRE 65 +I G L G +R S +NPATG V+ ++ +V AAV AA A W + R E Sbjct: 13 LINGVLVDGEGERQSVYNPATGEVILEIAEASPAQVDAAVQAADNAFAEWGQTTPKARAE 72 Query: 66 YLNRVADAIAANAERLATLVTQEQGRPLGGVGPGQVPG--SRFELWGCEAWTRATASLEL 123 L ++AD+I NA A L +Q G+PL V ++P F + A R + L Sbjct: 73 CLLKLADSIEQNALEFARLESQNCGKPLHCVINDEIPAIVDVFRFFAGAA--RCLSGLAA 130 Query: 124 APEVVFEDETRRDELHRKPYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSV 183 + E + R P GV+A+IAPWN+PLM++ W++ PAL AGN VV+KPSE T + Sbjct: 131 GEYL----EGHTSMIRRDPIGVVASIAPWNYPLMMAAWKLAPALAAGNCVVIKPSEITPL 186 Query: 184 CGLELARVVADALPPGVLNTVSGDG-SVGAMLVEDGDVNKIMFTGSGATGARIVAAAARN 242 L+LA + D PPGVLN + G G +VG +L V + TGS ATG I+ A Sbjct: 187 TALKLAVLAKDIFPPGVLNVLFGRGQTVGDVLTGHEKVRMVSLTGSIATGEHILRHTAPA 246 Query: 243 LTPTTMELGGNDAAIVLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDE 302 + T MELGG IV DDAD A+A G+ F N GQ C A R+Y ++D +V++ Sbjct: 247 IKRTHMELGGKAPVIVFDDADLDAVAQGVRTFGFYNAGQDCTAACRIYAQRGIYDALVEK 306 Query: 303 LKAIIAALPMGDGLQPGIAMGPVQNPMQLKKVVALVESAREEGGT-IVCGGVLPDGPGNF 361 L +++L MG +GP+ + LK+V A VE A+ ++ GG +G G + Sbjct: 307 LGNAVSSLKMGAPEDESTELGPLSSLAHLKRVTAAVEEAKALSHIRVITGGSQTEGKGYY 366 Query: 362 YPLTLVTGLRDGARLVDEEQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRAA 421 + TL+ + +V E FGPV+ I + D +Q + AN GL +SVW+ D RA Sbjct: 367 FAPTLLADAKQEDAIVQREVFGPVVSITVFDDEDQVLRWANDSRYGLASSVWTQDVGRAH 426 Query: 422 QVATRLQAGTVWVNQHGMVHPMVPFGGNKRSGWGVEFGQEGLKGVTQPQVISLKK 476 +++ RLQ G W+N H M+ +P GG K+SG+G + GL+ T + I +K Sbjct: 427 RLSARLQYGCTWINTHFMLVSEMPHGGQKQSGYGKDMSLYGLEDYTLVRHIMVKH 481 >mlr5385 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Mesorhizobium loti Length = 475 Score = 267 bits (683), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 168/466 (36%), Positives = 254/466 (54%), Gaps = 11/466 (2%) Query: 7 IIGGQLRAGSRQRDS-HNPATGAVMGRFPQSDAIEVAAAVAAARQAQPAWAALSLVQRRE 65 +IG + G+ +S NP TGA + P++ ++ AAVAAA +A +W+ + QR Sbjct: 6 LIGSKFENGAETEESILNPKTGATILNLPEASQAQIEAAVAAAEKAFVSWSRTTPAQRSG 65 Query: 66 YLNRVADAIAANAERLATLVTQEQGRPLGGVGPGQVPGSRFELWGCEAWTRATASLELAP 125 YL ++AD I A A+ A L G+P+ V ++P + + ++ P Sbjct: 66 YLLKIADRIEAEAKEFAALEALNCGKPINSVLNDEIPAI------VDCYRFFAGAVRSMP 119 Query: 126 EVVFEDET--RRDELHRKPYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSV 183 VV + + R P G++A+IAPWN+PLM+ W++ PA+ GNTVV KPSE T + Sbjct: 120 GVVAGEYLPGHTSMVRRDPIGIVASIAPWNYPLMMMAWKLAPAIGGGNTVVFKPSEQTPL 179 Query: 184 CGLELARVVADALPPGVLNTVSGDG-SVGAMLVEDGDVNKIMFTGSGATGARIVAAAARN 242 L LAR++A+ LP GV+N V G G SVG L+ VN I TG ATG +++ AAA++ Sbjct: 180 TALRLARILAEILPEGVVNVVLGRGDSVGNALINHPKVNMISITGDVATGKKVLQAAAKS 239 Query: 243 LTPTTMELGGNDAAIVLDDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDE 302 + T +ELGG IV DDAD A+ GL + N GQ C A R+Y ++D++V + Sbjct: 240 VKRTHLELGGKAPVIVFDDADLGAVVNGLRAFGYYNAGQDCTAACRIYAGKKIYDKLVAD 299 Query: 303 LKAIIAALPMGDGLQPGIAMGPVQNPMQLKKVVALVESARE-EGGTIVCGGVLPDGPGNF 361 L + ++ + +GP+ + Q +V + VE A E + I GG +G G + Sbjct: 300 LSSAVSTIKYNQPDDTENEIGPLISRRQRDRVSSFVERASELKHIEITTGGRPGEGTGFY 359 Query: 362 YPLTLVTGLRDGARLVDEEQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRAA 421 Y T+V G +V E FGPV+ I R++++++A+ AN D GL +SVW+ D RA Sbjct: 360 YQPTVVAGALQEDEIVRREVFGPVVSITRFTEVDEAVNWANDSDYGLASSVWTKDVSRAM 419 Query: 422 QVATRLQAGTVWVNQHGMVHPMVPFGGNKRSGWGVEFGQEGLKGVT 467 A RLQ G W+N H M+ +P GG K+SG+G + L+ T Sbjct: 420 ATAARLQYGCTWINTHFMLTNEMPHGGLKQSGYGKDMSLYALEDYT 465 >PA0265 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 483 Score = 263 bits (671), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 161/455 (35%), Positives = 241/455 (52%), Gaps = 7/455 (1%) Query: 22 HNPATGAVMGRFPQSDAIEVAAAVAAARQAQPAWAALSLVQRREYLNRVADAIAANAERL 81 +NPATG ++G P+ A E A+ AA +A PAW AL+ +R L R D + N + L Sbjct: 31 NNPATGEIIGSVPKMGAAETRRAIEAADKALPAWRALTAKERANKLRRWFDLMIENQDDL 90 Query: 82 ATLVTQEQGRPLGGVGPGQVPGSRFELWGCEAWTRATASLELAPEVVFEDETRRDELHRK 141 A L+T EQG+PL + F W E R + +R + ++ Sbjct: 91 ARLMTIEQGKPLAEAKGEIAYAASFLEWFGEEAKRIYGDT-----IPGHQPDKRIIVIKQ 145 Query: 142 PYGVIAAIAPWNWPLMISIWQVIPALYAGNTVVLKPSEYTSVCGLELARVVADA-LPPGV 200 P GV AAI PWN+P + + PAL AG T+VLKP+ T L LA + A +P GV Sbjct: 146 PIGVTAAITPWNFPSAMITRKAGPALAAGCTMVLKPASQTPYSALALAELAERAGIPKGV 205 Query: 201 LNTVSGD-GSVGAMLVEDGDVNKIMFTGSGATGARIVAAAARNLTPTTMELGGNDAAIVL 259 + V+G G VG L + V K+ FTGS G +++A A+++ ++ELGGN IV Sbjct: 206 FSVVTGSAGEVGGELTSNPIVRKLTFTGSTEIGRQLMAECAQDIKKVSLELGGNAPFIVF 265 Query: 260 DDADPKAIAPGLFWGAFLNMGQTCACAKRLYVPDALHDQIVDELKAIIAALPMGDGLQPG 319 DDAD A G + N GQTC CA RLYV D ++D VD+LKA +A L +G+GL+ G Sbjct: 266 DDADLDAAVEGALISKYRNNGQTCVCANRLYVQDGVYDAFVDKLKAAVAKLNIGNGLEAG 325 Query: 320 IAMGPVQNPMQLKKVVALVESAREEGGTIVCGGVLPDGPGNFYPLTLVTGLRDGARLVDE 379 + GP+ + + KV + A +G +V GG G F+ T++ + A + + Sbjct: 326 VTTGPLIDAKAVAKVEEHIADAVSKGAKVVSGGKPHALGGTFFEPTILVDVPKNALVSKD 385 Query: 380 EQFGPVLPIIRYSDLEQAIANANRLDVGLGASVWSSDSQRAAQVATRLQAGTVWVNQHGM 439 E FGP+ P+ R+ D + IA +N + GL + ++ D R +VA +L+ G V +N + Sbjct: 386 ETFGPLAPVFRFKDEAEVIAMSNDTEFGLASYFYARDLARVFRVAEQLEYGMVGINTGLI 445 Query: 440 VHPMVPFGGNKRSGWGVEFGQEGLKGVTQPQVISL 474 + + PFGG K SG G E + G++ + + + L Sbjct: 446 SNEVAPFGGIKASGLGREGSKYGIEDYLEIKYLCL 480