BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0037.p (304 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2187 [GER] COG0697 Permeases of the drug/metabolite transport... 357 2e-98 BS_ycbK [GER] COG0697 Permeases of the drug/metabolite transport... 111 2e-24 DR0512 [GER] COG0697 Permeases of the drug/metabolite transporte... 68 3e-11 RSc1002 [GER] COG0697 Permeases of the drug/metabolite transport... 64 5e-10 >RSc2187 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 308 Score = 357 bits (916), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 195/300 (65%), Positives = 234/300 (78%), Gaps = 2/300 (0%) Query: 3 AATPHPTPRQAFLGGLLLAIVGAVFFSAKAIVAKLMYRYHVDAVMVITLRMVFSFPMFAA 62 +A+P T R A GGLLLA VGAV FSAKAIVAKLMYRY +DAVMVITLRM+ + P+F A Sbjct: 6 SASPAST-RPADAGGLLLASVGAVLFSAKAIVAKLMYRYQIDAVMVITLRMLLAAPLFMA 64 Query: 63 VALWKARTQPPLGRGDGWRIVVLGLMGYYLSSFLDFLGLQYISAGLERLILFLTPSFVML 122 + W++R PL D WRIV LGL+GYYLSSFLDFLGLQYI+AGLERLILFLTPSFV+L Sbjct: 65 MGWWQSRRAAPLAPADRWRIVGLGLIGYYLSSFLDFLGLQYITAGLERLILFLTPSFVLL 124 Query: 123 IAFFFFKRKVGWIEWAALLVSYFGTVLVLQHDLHVGGSDVILGSALVLGSAFSYSIYLIS 182 I FKR++ ++W ++ ++Y G V+V HDL +GG V LG LVL SA SY IYL++ Sbjct: 125 ITATVFKRRITGLQWLSMAIAYAGIVMVFAHDLGLGGRHVWLGGGLVLASALSYGIYLLA 184 Query: 183 SGELVRRVGAVRLVAYAMCVSSVACVIQFFVLRAPADLLTQVAPVYQLSLFNAVFCTVLP 242 SGELVRRVG++RLVAYAMCVS+VAC++QFFVLR P L VY LS N+VFCTV P Sbjct: 185 SGELVRRVGSMRLVAYAMCVSTVACMVQFFVLR-PVSALVLPWQVYGLSAINSVFCTVAP 243 Query: 243 VFLTMVAVARIGAPTAAQAGLVGPVSTLFMGAVLLDEPITALQLVGTALVLAGMWLLSRK 302 V LTM+AVAR+GAP A+QAG++GPVSTL +G LL EPIT Q+ G+ALVLAGM LLSR+ Sbjct: 244 VTLTMMAVARVGAPVASQAGMIGPVSTLLLGWWLLGEPITLWQVGGSALVLAGMALLSRR 303 >BS_ycbK [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 312 Score = 111 bits (278), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 95/311 (30%), Positives = 158/311 (50%), Gaps = 30/311 (9%) Query: 4 ATPHPTPRQAFLGGLLLAIVGAVFFSAKAIVAKLMYRYHVDAVMVITLRMVFSFPMFAAV 63 A R+A G + L ++G V F++K+I K Y+ + V+ R + + P+F + Sbjct: 3 AEEQSKIREAAAGTIFL-LIGTVCFASKSIWIKWAYQMGAEPDAVLLYRQLLAVPLFWLI 61 Query: 64 ALWKARTQPPL----GRGDGWRIVVLGLMGYYLSSFLDFLGLQYISAGLERLILFLTPSF 119 L +PP+ +GD W+ G+ ++LS LDF+GL ++SA +ER++L P F Sbjct: 62 FL---IYRPPMPDGKKKGDLWKACGAGVFCFFLSPLLDFIGLNHVSAMVERILLMSYPLF 118 Query: 120 VMLIAFFFFKRKVGWIEWAALLVSYFGTVLVLQHDLHVGGSDVILGSALVLGSAF----- 174 V ++ + A+L FG L L GG + L A ++G+ F Sbjct: 119 VFGFTACRDRKMSSIQDLFAVLAVMFGLFLAL------GGWNAELFQANMIGAVFILLSS 172 Query: 175 -SYSIYLISSGELVRRVGAVRLVAYAMCVSSVACVIQFFVLRAPADLLTQVAPVYQLSLF 233 Y+ YL+ SG LV ++G +RL AY M + A ++ + +++ A + T +A Y LS++ Sbjct: 173 AVYAGYLVLSGHLVHQIGGIRLNAYGMTAAGAAMML-YTGIKSAAGMNTPMA-AYPLSMY 230 Query: 234 N-----AVFCTVLPVFLTMVAVARIGAPTAAQAGLVGPVSTLFMGAVLLDEPITALQLVG 288 AV TV+P L + + RIGA AA + GP+ T+F GA+ L E + +Q++G Sbjct: 231 GLFAVIAVVTTVIPFVLMLEGIKRIGAQRAAAISMAGPILTIFYGALFLGERLGLIQVIG 290 Query: 289 TA---LVLAGM 296 V+ GM Sbjct: 291 CGGVFFVITGM 301 >DR0512 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Dra Deinococcus radiodurans Length = 301 Score = 67.8 bits (164), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 75/268 (27%), Positives = 123/268 (45%), Gaps = 20/268 (7%) Query: 38 MYRYHVDAVMVITLRMVFSFPMFAAVALWKARTQPPLGRGDGWRIVVLGLMGYYLSSFLD 97 +YR+ V +V ++ + V P+ P R D W+I VL + G L L Sbjct: 51 LYRFLVASVTLLLVMAVTRLPV-------------PAPR-DLWQIGVLSVAGISLYHVLL 96 Query: 98 FLGLQYISAGLERLILFLTPSFVMLIAFFFFKRKVGWIEWAALLVSYFGTVL-VLQHDLH 156 +G + + AG LI+ P L+A F + + W VS G L VL Sbjct: 97 NMGERSVPAGTASLIIAAGPVITALLAARFLGESLNPLGWLGTAVSLGGVALIVLGQGQG 156 Query: 157 VGGSDVILGSALVLGSAFSYSIYLISSGELVRRVGAVRLVAYAMCVSSVACVIQFFVLRA 216 +G S G+ LVLG+AF S+Y + ++ RVG++R +++ + +V ++ F+ Sbjct: 157 LGFSA---GALLVLGAAFFTSLYFVFQKGVLARVGSLRFTVWSLILGTVPLLV--FLPGF 211 Query: 217 PADLLTQVAPVYQLSLFNAVFCTVLPVFLTMVAVARIGAPTAAQAGLVGPVSTLFMGAVL 276 +L P + L+ VF + L A++R+GA + V PV L M L Sbjct: 212 GTELRAAPLPAHLAVLYLGVFPSALAYLTWTFAISRVGAGVTSSFLYVSPVFALLMAWAL 271 Query: 277 LDEPITALQLVGTALVLAGMWLLSRKKR 304 L E A+ L+G + LAG+ L++ + R Sbjct: 272 LGEVPGAVTLLGGVIALAGVLLVNTRGR 299 >RSc1002 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 312 Score = 63.5 bits (153), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 90/296 (30%), Positives = 130/296 (43%), Gaps = 21/296 (7%) Query: 17 GLLLAIVGAVFFSAKAIVAKLMYRYHVDAVMVITLRMVFSFPMFAAVALWKART--QPPL 74 G+LL V A F A AI Y D V ++ +R FS A A+ + R PP Sbjct: 20 GVLLIAVSAASFGAMAIFTHYAYASGADTVGLLAVR--FSLAALALTAVMRVRRIGLPPW 77 Query: 75 GRGDGWRIVVLGLMGYYLSSFLDFLGLQYISAGLERLILFLTPSFVMLIAFFFFKRKVGW 134 R G + +G +GY SF F L Y A L L+L+L P FV ++A F ++ Sbjct: 78 PRVAG--LAAMGGIGYAGQSFAFFTALHYAPASLVALLLYLYPMFVTVLAAVFLHERLTP 135 Query: 135 IEWAALLVSYFGTVLVLQHDLHVGGSD--VILGSALVLGSAFSYSIYLISSGELVRRVGA 192 AL++ G L + GGS V+LG A +A YS+Y+ + R V Sbjct: 136 AALLALVLCSVGAGLTVGGAGLAGGSATGVVLGVA----AAVIYSVYITVGARVTRGVDP 191 Query: 193 V---RLVAYAMCVSSVACVIQFFVLRAPADLLTQVAPVYQLSLFNAVFCTVLPVFLTMVA 249 + L+ A V + R P + A +L A TV+ + Sbjct: 192 IACTTLICTAAAVVYAGAAVAGVPARFPGSVAGWAA-----ALAIAGLSTVIAILAFFAG 246 Query: 250 VARIGAPTAAQAGLVGPVSTLFMGAVLLDEPITALQLVGTALVLAG-MWLLSRKKR 304 + R+GA A+ + PV T+ + A+LL E I A Q+ G AL+LAG +WL R Sbjct: 247 LQRLGAAQASMLSTLEPVVTVALAALLLGESIGAAQMAGGALILAGVLWLTRADAR 302