BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0020.p (1135 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2205 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralsto... 1483 0.0 NMB1827 [L] COG0587 DNA polymerase III, alpha subunit Nme Neisse... 1114 0.0 NMA0632 [L] COG0587 DNA polymerase III, alpha subunit NmA Neisse... 1105 0.0 PA3640 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudom... 1082 0.0 ZdnaE [L] COG0587 DNA polymerase III, alpha subunit EcZ Escheric... 1032 0.0 ECs0186 [L] COG0587 DNA polymerase III, alpha subunit Ecs Escher... 1032 0.0 STM0231 [L] COG0587 DNA polymerase III, alpha subunit Sty Salmon... 1029 0.0 dnaE [L] COG0587 DNA polymerase III, alpha subunit Eco Escherich... 1029 0.0 YPO1059 [L] COG0587 DNA polymerase III, alpha subunit Ype Yersin... 1025 0.0 VC2245 [L] COG0587 DNA polymerase III, alpha subunit Vch Vibrio ... 1018 0.0 >RSc2205 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralstonia solanacearum Length = 1173 Score = 1483 bits (3840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 753/1161 (64%), Positives = 896/1161 (77%), Gaps = 32/1161 (2%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 VDG VR+D+ VKAAA DG ALA+TDLAN F +VRFYKEARGKGVKPI G D+WITN + Sbjct: 18 VDGNVRLDEAVKAAAADGMGALALTDLANAFGLVRFYKEARGKGVKPIVGADVWITNHDE 77 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEG--GNGLIA 118 R+KP RLL+L++N+ GYL LC +L++AWL+NQ++GRAEV EW +E GL+A Sbjct: 78 RDKPSRLLLLVRNKQGYLNLCMLLARAWLSNQHRGRAEVAPEWFGEPGVEEAPMATGLLA 137 Query: 119 LSGAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGA 178 LSGA GDIG A+ NGN A A A +W+++FP +FY+ELQRAG A E V+Q+V L A Sbjct: 138 LSGAMGGDIGMALANGNEALARKLATQWSQVFPASFYIELQRAGNAGTEAYVQQAVKLAA 197 Query: 179 KLGLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVELF 238 + LP VATHP+QF +P++F AHEAR CIAEG+++AN RR RRF QYFK+Q EM LF Sbjct: 198 SMQLPVVATHPVQFMTPDDFTAHEARVCIAEGDLLANPRRTRRFTTDQYFKTQDEMCALF 257 Query: 239 ADLPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELFP 298 AD+P A+ANT +IA+RCNL L+LGKP+LP FPTPDGM++DD+LV K GLE R+ LFP Sbjct: 258 ADIPSALANTAQIAQRCNLTLELGKPKLPLFPTPDGMSLDDYLVHLAKDGLEKRMAVLFP 317 Query: 299 NEAEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGSL 358 +EA RE +RP Y ARLEFE TIIKM FPGYFLIVADFI WAKNNGVPVGPGRGSGAGSL Sbjct: 318 DEAVREAKRPEYYARLEFETGTIIKMGFPGYFLIVADFINWAKNNGVPVGPGRGSGAGSL 377 Query: 359 VAYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVSQ 418 VAY L ITDLDPL+YNLLFERFLNPERVSMPDFDIDFCQ GRDRVI YVK++YGK+AVSQ Sbjct: 378 VAYALGITDLDPLKYNLLFERFLNPERVSMPDFDIDFCQHGRDRVIHYVKEKYGKDAVSQ 437 Query: 419 IATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLEN 478 IATFGTMAAK AVRDVGRVLDLGYNF DG++KLIPFKPGKLVT+ +A +EEPLL ER N Sbjct: 438 IATFGTMAAKAAVRDVGRVLDLGYNFVDGVAKLIPFKPGKLVTIEEAKKEEPLLAEREAN 497 Query: 479 EEEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGG-DSGVVSQYDKDDV 537 EEEVKQL+ LAQ+VEG+ RN+GMHAGGVLIAPGKLTDFCPLYTQGG D+GVVSQYDKDDV Sbjct: 498 EEEVKQLLELAQRVEGMTRNVGMHAGGVLIAPGKLTDFCPLYTQGGEDAGVVSQYDKDDV 557 Query: 538 EAVGLVKFDFLGLTTLTILDRAVRYIRMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAV 597 EAVGLVKFDFLGLTTLTILD A RYIR LDP+ AD++ + +PL D+ ++++L A TVAV Sbjct: 558 EAVGLVKFDFLGLTTLTILDWAERYIRTLDPSRADWNCSHIPLTDKAAFDILKTANTVAV 617 Query: 598 FQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFCKRKHG-EAFDYPDPRTEG 656 FQLESRGMQGMLKDA+PDRFEDIIALVALYRPGPMDLIP FC RKHG E +YPDPR E Sbjct: 618 FQLESRGMQGMLKDAKPDRFEDIIALVALYRPGPMDLIPSFCARKHGREKVEYPDPRVEP 677 Query: 657 ILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFREGAAKNG 716 +L ETYGIMVYQEQVMQMAQ++GGYSLGGADLLRRAMGKKKAEEMA+HRELFR GAAK+G Sbjct: 678 VLKETYGIMVYQEQVMQMAQIVGGYSLGGADLLRRAMGKKKAEEMAEHRELFRGGAAKDG 737 Query: 717 LDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSLAMEDTD 776 L KADEIFDLMEKFAGYGFNKSHAAAYALL+YYTA+LKAHHPA FMAAN+SLAM+DTD Sbjct: 738 LSTEKADEIFDLMEKFAGYGFNKSHAAAYALLAYYTAWLKAHHPAEFMAANMSLAMDDTD 797 Query: 777 KVKILIEDAIDICKLAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQNAIEAI 836 KVKIL +DA LA+LPPDIN S YRF P A IRYGLG VKG+GQ AIE I Sbjct: 798 KVKILYDDARGKNGLAVLPPDINASQYRFTPT-----DAKTIRYGLGGVKGSGQGAIEDI 852 Query: 837 LEARKSGPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVNLAWESAE 896 L AR+ GPFKDLFDF +RVD++Q+NRRTI++L+RAGAFD +RA L S+ LA E+AE Sbjct: 853 LRAREDGPFKDLFDFCERVDRRQVNRRTIEALVRAGAFDSLNANRAQLLVSIGLAMEAAE 912 Query: 897 QAEKSANQVSLF---GGDDSDLEAPLEYVQVPPWSDKQRLTEEKGALGFYLSGHLFSAYE 953 Q +ANQVSLF G DD++ P E + PWS K++L EEK ALGFYLSGHLF Sbjct: 913 QKAAAANQVSLFDLMGSDDAEQHRP-ELLDEAPWSTKRKLQEEKQALGFYLSGHLFDECR 971 Query: 954 KEVRRFVRTKIASL---------------EPSWEPRSLAGIITGVRVQMTQRGKLVICTL 998 EVRRF RT +A L +++AG+I G+R QMTQRGK+++ L Sbjct: 972 DEVRRFARTTLADLAREVNGNGNNGGGYGSRDARNKTVAGVIVGLRTQMTQRGKMIVVML 1031 Query: 999 DDGTG--VIEATIYNELFEPFKHIIKEDELLVVSGKVSEDRFNGGLRVAADKVMDLGAAR 1056 DDG+ E T++NELF+ + + KEDE+L+V G D F GG+R+ A+ V+DL AR Sbjct: 1032 DDGSQSEATEVTVFNELFDANRALFKEDEVLIVQGNARHDTFTGGVRMTAEAVLDLTQAR 1091 Query: 1057 IQYGVRMVVSINKAIDPNHLRDTLSAHRQEQ--GLPFVMRYQQADAACEVVLGDAWRINP 1114 +Y + ++ LR+ L+ + Q G+ + Y A CE VLG+ W++ P Sbjct: 1092 ARYADAIGLTFRDNASAARLRELLTPYLAAQVPGVRVRISYAANGARCEAVLGEQWQVTP 1151 Query: 1115 SDSLQSTLVASFGKEAVVVEY 1135 SD + ++ ++ E V + Y Sbjct: 1152 SDEVLASFRSALSTENVYMIY 1172 >NMB1827 [L] COG0587 DNA polymerase III, alpha subunit Nme Neisseria meningitidis MC58 Length = 1144 Score = 1114 bits (2881), Expect = 0.0, Method: Compositional matrix adjust. Identities = 580/1146 (50%), Positives = 773/1146 (67%), Gaps = 30/1146 (2%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 DG+VRI ++ A + G AL ++DL N F +V+FYK R G+KPI D+ I N Sbjct: 18 TDGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSAGIKPIGAADVRIGNPDA 77 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWL-NNQYKGRAEVRMEWLDALRHQEGGN-GLIA 118 +KPFR +++I+N GYL+L E+L+ A++ ++ AE+ EWL + G N GLI Sbjct: 78 PDKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHHAELNPEWL-----ENGDNSGLIC 132 Query: 119 LSGAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQ-ANMEVQVRQSVALG 177 LSGA G++G + NGN A A ++A FP AFY+ELQR + E V SV L Sbjct: 133 LSGAHYGEVGVNLLNGNEDAARTAALKYAAWFPDAFYMELQRLPERPEWEACVSGSVKLA 192 Query: 178 AKLGLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVEL 237 +LGLP VATHP QF S ++F AHEAR CIA G ++ + +R R F Q+F M E Sbjct: 193 EELGLPVVATHPTQFMSRDDFNAHEARVCIAGGWVLTDKKRPRDFTPGQFFIPPETMAER 252 Query: 238 FADLPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELF 297 FADLP A+ NTVEIAKRCNL + LGK LP FPTPDG+++DD+L+ + GL+ R+ +L+ Sbjct: 253 FADLPEALENTVEIAKRCNLHITLGKNFLPLFPTPDGLSLDDYLIKLSNEGLQERMVQLY 312 Query: 298 PNEAEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGS 357 P+EAER + P Y+ RL+FE N II+MKFPGYFLIV DFI WAK +G PVGPGRGSGAGS Sbjct: 313 PDEAERAAKMPEYQERLDFELNIIIQMKFPGYFLIVQDFINWAKTHGCPVGPGRGSGAGS 372 Query: 358 LVAYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVS 417 LVAY L ITDLDPL+Y LLFERFLNPERVSMPDFD+DFCQ R RVI+YV+++YG EAVS Sbjct: 373 LVAYSLKITDLDPLKYALLFERFLNPERVSMPDFDVDFCQSNRGRVIEYVREKYGAEAVS 432 Query: 418 QIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLE 477 QI TFGTM++K +RDVGRVL+L + CD +SKLIP + K ++L A+E EP ++E +E Sbjct: 433 QIVTFGTMSSKAVIRDVGRVLELPFMLCDKLSKLIPLEANKPLSLEKAMETEPQIQELIE 492 Query: 478 NEEEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDV 537 EE +L+ LA+++E + R +GMHAGGVLIAPGK++D+ P+Y + VS YDK DV Sbjct: 493 -AEEADELITLAKKLEDLTRGLGMHAGGVLIAPGKISDYSPVYQADESASPVSMYDKGDV 551 Query: 538 EAVGLVKFDFLGLTTLTILDRAVRYIRMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAV 597 E VGLVKFDFLGL LTI++ A I+ + D+ K+PLDD+ +Y++ A T AV Sbjct: 552 EDVGLVKFDFLGLRNLTIIEMAQNNIKNTTGDI--IDVGKIPLDDQVAYQIFRDANTTAV 609 Query: 598 FQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFCKRKHGEAFDYPDPRTEGI 657 FQ ES GM+ MLK A +FE++IA V+LYRPGPMD IPDF R G+ F Y P EGI Sbjct: 610 FQFESTGMKKMLKTAHTTKFEELIAFVSLYRPGPMDNIPDFVARMKGQEFQYIHPLLEGI 669 Query: 658 LSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFREGAAKNGL 717 L+ TYGIMVYQEQVMQ AQ+IGGYSLGGADLLRRAMGKKK EEM KHRE+F EGAAK G+ Sbjct: 670 LAPTYGIMVYQEQVMQAAQIIGGYSLGGADLLRRAMGKKKPEEMVKHREIFAEGAAKQGI 729 Query: 718 DQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSLAMEDTDK 777 + K+DEIF+ MEKFAGYGFNKSHAAAYAL+SY TA+LKAH+PA FMAA +S +++TD+ Sbjct: 730 SREKSDEIFNYMEKFAGYGFNKSHAAAYALISYQTAWLKAHYPAEFMAATMSSELDNTDQ 789 Query: 778 VKILIEDAIDICK---LAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQNAIE 834 +K +D C+ + LPPDIN+SDYRF P + +IRY LGA+KG G+ A+E Sbjct: 790 LKHFYDD----CRANGIEFLPPDINESDYRFTPYPD-----MKIRYALGAIKGTGEAAVE 840 Query: 835 AILEARKS-GPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVNLAWE 893 +I AR+S G F L DF +RV K+ +NRRT+++LIR GAFD + +RA+L A+++LA + Sbjct: 841 SITAARQSGGKFTGLLDFCERVGKEHMNRRTLEALIRGGAFDSIEPNRAMLLANIDLAMD 900 Query: 894 SAEQAEKSANQVSLFGGDDSDLEAPLEYVQVPPWSDKQRLTEEKGALGFYLSGHLFSAYE 953 +A+Q +ANQ LF + +E P+ + P WS+ ++L EEK +GFYLSGH F Y Sbjct: 901 NADQKAANANQGGLFDMMEDAIE-PVRLIDAPMWSESEKLAEEKTVIGFYLSGHPFGPYA 959 Query: 954 KEVRRFVRTKIASLEPSWEPRSLAGIITGVRVQMTQRGKLVICTLDDGTGVIEATIYNEL 1013 +EVR+ TK+ L+P R LAG +T VR M +RGK+ +L+D +G +E + + Sbjct: 960 QEVRQIAPTKLDRLKPQDSVR-LAGFVTAVRTMMGKRGKIAFVSLEDLSGQVEIMVGGQT 1018 Query: 1014 FEPFKHIIKEDELLVVSGKVSEDRFNG--GLRVAADKVMDLGAARIQYGVRMVVSINKAI 1071 E +K D++L++ KVS D + G GLR+ A++VM L AR +Y + +++ Sbjct: 1019 LENCADCLKADQVLIIESKVSRDDYGGGDGLRILANQVMTLQTARERYARSLSLALAPHH 1078 Query: 1072 DPNHLRDTLSAHR--QEQGLPFVMRYQQADAACEVVLGDAWRINPSDSLQSTLVASFGKE 1129 D L L+AH+ +P + Y A+ + + W + PS +L L G Sbjct: 1079 DIGGLVRLLAAHQLPDTPRIPLQLSYANEKASGRLQVPPKWTVTPSSALFGELETLLGSR 1138 Query: 1130 AVVVEY 1135 +V V + Sbjct: 1139 SVRVNW 1144 >NMA0632 [L] COG0587 DNA polymerase III, alpha subunit NmA Neisseria meningitidis Z2491 Length = 1144 Score = 1105 bits (2859), Expect = 0.0, Method: Compositional matrix adjust. Identities = 580/1146 (50%), Positives = 772/1146 (67%), Gaps = 30/1146 (2%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 DG+VRI ++ A + G AL ++DL N F +V+FYK R G+KPI D+ I N Sbjct: 18 TDGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSAGIKPIGAADVRIGNPDA 77 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWL-NNQYKGRAEVRMEWLDALRHQEGGN-GLIA 118 +KPFR +++I+N GYL+L E+L+ A++ ++ AE+ EWL + G N GLI Sbjct: 78 PDKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHHAELNPEWL-----ENGDNSGLIC 132 Query: 119 LSGAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQ-ANMEVQVRQSVALG 177 LSGA G++G + NGN A A A ++A FP AFYLELQR + E V SV L Sbjct: 133 LSGAHYGEVGVNLLNGNEDAARAAALKYAAWFPDAFYLELQRLPERPEWEACVSGSVKLA 192 Query: 178 AKLGLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVEL 237 +LGLP VATHP QF S ++F AHEAR CIA G ++ + +R R F Q+F M E Sbjct: 193 EELGLPVVATHPTQFMSRDDFNAHEARVCIAGGWVLTDKKRPRDFTPSQFFIPPETMAER 252 Query: 238 FADLPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELF 297 F+DLP A+ NTVEIAKRCNL + LGK LP FPTPDG+++DD+LV + GL+ R+ +L+ Sbjct: 253 FSDLPEALENTVEIAKRCNLHITLGKNFLPLFPTPDGLSLDDYLVKLSNEGLQERMVQLY 312 Query: 298 PNEAEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGS 357 P+EAER + P Y+ RL+FE N II+MKFPGYFLIV DFI WAK +G PVGPGRGSGAGS Sbjct: 313 PDEAERAAKMPEYQERLDFELNIIIQMKFPGYFLIVQDFINWAKTHGCPVGPGRGSGAGS 372 Query: 358 LVAYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVS 417 LVAY L ITDLDPL+Y LLFERFLNPERVSMPDFD+DFCQ R RVI+YV+++YG EAVS Sbjct: 373 LVAYSLKITDLDPLKYALLFERFLNPERVSMPDFDVDFCQANRGRVIEYVREKYGAEAVS 432 Query: 418 QIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLE 477 QI TFGTM++K +RDVGRVL+L + CD +SKLIP + K + L DA++ EP ++E +E Sbjct: 433 QIVTFGTMSSKAVIRDVGRVLELPFTLCDKLSKLIPLEANKPLGLDDAMKAEPQIQELIE 492 Query: 478 NEEEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDV 537 EE +L+ LA+++E + R +GMHAGGVLIAPGK++D+ P+Y + VS YDK DV Sbjct: 493 -AEEADELITLAKKLEDLTRGLGMHAGGVLIAPGKISDYSPVYQADESASPVSMYDKGDV 551 Query: 538 EAVGLVKFDFLGLTTLTILDRAVRYIRMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAV 597 E VGLVKFDFLGL LTI++ A I+ + D+ +PLDD+ +Y++ A T AV Sbjct: 552 EDVGLVKFDFLGLRNLTIIEMAQNNIKNTTGDIV--DVGTIPLDDQTAYQIFRDANTTAV 609 Query: 598 FQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFCKRKHGEAFDYPDPRTEGI 657 FQ ES GM+ MLK A +FE++IA V+LYRPGPMD IPDF R G+ F Y P EGI Sbjct: 610 FQFESTGMKKMLKTAHTTKFEELIAFVSLYRPGPMDNIPDFVARMKGQEFQYIHPLLEGI 669 Query: 658 LSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFREGAAKNGL 717 L+ TYGIMVYQEQVMQ AQ+IGGYSLGGADLLRRAMGKKK EEM KHRE+F EGAAK G+ Sbjct: 670 LAPTYGIMVYQEQVMQAAQIIGGYSLGGADLLRRAMGKKKPEEMVKHREIFAEGAAKQGI 729 Query: 718 DQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSLAMEDTDK 777 + K+DEIF+ MEKFAGYGFNKSHAAAYAL+SY TA+LKAH+PA FMAA +S +++TD+ Sbjct: 730 SREKSDEIFNYMEKFAGYGFNKSHAAAYALISYQTAWLKAHYPAEFMAATMSSELDNTDQ 789 Query: 778 VKILIEDAIDICK---LAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQNAIE 834 +K +D C+ + LPPDIN+SDYRF P + +IRY LGA+KG G+ A+E Sbjct: 790 LKHFYDD----CRANGIEFLPPDINESDYRFTPYPD-----MKIRYALGAIKGTGEAAVE 840 Query: 835 AILEARKS-GPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVNLAWE 893 +I AR+S G F L DF +RV K+ +NRRT+++LIR GAFD + +RA+L A+++LA Sbjct: 841 SITSARQSGGKFTGLLDFCERVGKEHMNRRTLEALIRGGAFDSIEPNRAMLLANIDLAMN 900 Query: 894 SAEQAEKSANQVSLFGGDDSDLEAPLEYVQVPPWSDKQRLTEEKGALGFYLSGHLFSAYE 953 +A+Q +ANQ LF + +E P+ + P WS+ ++L EEK +GFYLSGH F Y Sbjct: 901 NADQKAANANQGGLFDMMEDAIE-PVRLIDAPMWSESEKLAEEKTVIGFYLSGHPFGPYA 959 Query: 954 KEVRRFVRTKIASLEPSWEPRSLAGIITGVRVQMTQRGKLVICTLDDGTGVIEATIYNEL 1013 +EVR+ K++ L+P R LAG +T VR M +RGK+ +L+D +G +E + + Sbjct: 960 QEVRQIAPQKLSKLKPQDSVR-LAGFVTAVRTMMGKRGKIAFVSLEDLSGQVEIMVGGQT 1018 Query: 1014 FEPFKHIIKEDELLVVSGKVSEDRFNG--GLRVAADKVMDLGAARIQYGVRMVVSINKAI 1071 E +K D++L++ KVS D + G GLR+ A++VM L AR +Y + +++ Sbjct: 1019 LENCADCLKADQVLIIESKVSRDDYGGGDGLRILANQVMTLQTARERYARSLSLALAPHH 1078 Query: 1072 DPNHLRDTLSAHR--QEQGLPFVMRYQQADAACEVVLGDAWRINPSDSLQSTLVASFGKE 1129 D L L+AH+ +P + Y A+ + + W + PS +L L G Sbjct: 1079 DIGELVQLLAAHQLPDTPRIPLQLSYANEKASGRLQVPPKWTVTPSSALFGELETLLGSR 1138 Query: 1130 AVVVEY 1135 +V V + Sbjct: 1139 SVRVNW 1144 >PA3640 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudomonas aeruginosa Length = 1173 Score = 1082 bits (2799), Expect = 0.0, Method: Compositional matrix adjust. Identities = 589/1175 (50%), Positives = 778/1175 (66%), Gaps = 59/1175 (5%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 VDGLVR+ + KA A G A+AVTD +N+ +V+FYK A G G+KPI G D+W+ + + Sbjct: 17 VDGLVRVKPLAKAVAGLGMPAVAVTDQSNMCSLVKFYKTAMGAGIKPICGADIWLASREE 76 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 RL +L N GY L E++S+ W Q G + +W+ +E GLIALS Sbjct: 77 DGPLSRLSLLAMNAKGYRNLTELISRGWSEGQRNGEIIIERDWV-----KEAAEGLIALS 131 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAKL 180 A G+IG A+ +G A+AEA R W E+FP FY+E+QR + N E + +VAL ++ Sbjct: 132 AAKEGEIGHALLDGEEAKAEALLREWMEVFPERFYVEVQRTSRVNDEEHLHAAVALASRC 191 Query: 181 GLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVELFAD 240 P VAT+ ++F E+F AHE R CI EG + + RR R +++QQY KS AEM ELF+D Sbjct: 192 NAPLVATNDVRFIKQEDFEAHETRVCIGEGRTLDDPRRPRTYSDQQYLKSPAEMAELFSD 251 Query: 241 LPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELFPNE 300 LP A+ NTVEIAKRCN+ +QLGK LPDFPTP+GM IDD+L + GLE RL+ L P + Sbjct: 252 LPEALENTVEIAKRCNIEVQLGKYFLPDFPTPNGMGIDDYLRHASFEGLEERLEVLLPKD 311 Query: 301 A-EREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGSLV 359 + E +R Y RL FE + II+M FPGYFLIV DFI+WAKNNGVPVGPGRGSGAGSLV Sbjct: 312 TPDYEAKRQVYVDRLNFELDIIIQMGFPGYFLIVMDFIKWAKNNGVPVGPGRGSGAGSLV 371 Query: 360 AYCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVSQI 419 AY L ITDLDPL Y+LLFERFLNPER+SMPDFD+DFC EGRDRVI YV D YG+ AVSQI Sbjct: 372 AYVLKITDLDPLAYDLLFERFLNPERISMPDFDVDFCMEGRDRVIDYVADAYGRNAVSQI 431 Query: 420 ATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLENE 479 TFGTMAAK VRDV RV Y D +SK+IPF+ G +TL A E+E +L++ L+++ Sbjct: 432 ITFGTMAAKAVVRDVARVQGKSYGLADRLSKMIPFEVG--MTLDKAYEQEEMLRDFLKSD 489 Query: 480 EEVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDVEA 539 EE ++ +A ++EGI R G HAGGV+IAP KLTDF P+ G+V+Q+DKDDVEA Sbjct: 490 EEAAEIWEMALKLEGITRGTGKHAGGVVIAPTKLTDFSPIACDEEGGGLVTQFDKDDVEA 549 Query: 540 VGLVKFDFLGLTTLTILDRAVRYI------RMLDPAMADFDLAKLPLDDRPSYELLTKAK 593 GLVKFDFLGL TLTI+ A+ I + L+P DF +PLDD+P+Y LL KA+ Sbjct: 550 AGLVKFDFLGLRTLTIIKWAMEIINREQAKKGLEPVNIDF----IPLDDKPTYSLLQKAE 605 Query: 594 TVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFCKRKHGEA-FDYP 650 T AVFQLESRGM+ ++K +PD ED+IALVAL+RPGP+ ++ DF RKHG A YP Sbjct: 606 TTAVFQLESRGMKELIKKLKPDCLEDLIALVALFRPGPLQSGMVDDFINRKHGRAELSYP 665 Query: 651 DPR-----TEGILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHR 705 P E +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LRRAMGKKK EEMAK R Sbjct: 666 HPDYQYAGLEPVLKPTYGIILYQEQVMQIAQVMAGYTLGGADMLRRAMGKKKPEEMAKQR 725 Query: 706 ELFREGAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMA 765 F EG NG+D A IFDL+EKFAGYGFNKSH+AAY L+SY TA+LK H PA FMA Sbjct: 726 GGFIEGCKNNGIDADLAGNIFDLVEKFAGYGFNKSHSAAYGLVSYQTAWLKTHFPAPFMA 785 Query: 766 ANLSLAMEDTDKVKILIEDAIDICKLAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAV 825 A L+ M++TDKV LIE+ + KL I+ PD+N S++RF V + G+ I YGLGA+ Sbjct: 786 AVLTADMQNTDKVVTLIEECRHM-KLRIVAPDVNNSEFRFT-VDDDGR----IVYGLGAI 839 Query: 826 KGAGQNAIEAILEAR-KSGPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFD--------- 875 KG G+ +EAI E R + GPF LFDF RVD K+IN+RT+++LIRAGA D Sbjct: 840 KGVGEGPVEAITECRAEGGPFNTLFDFCDRVDLKRINKRTLEALIRAGALDRLGPHYHDE 899 Query: 876 ------CFKVDRAVLQASVNLAWESAEQAEKS--ANQVSLFGGDDSDLEAPL--EYVQVP 925 ++RAVL A++ A ++AEQ +S + + LFGG ++ EA + + +V Sbjct: 900 LKAYQATVDLNRAVLLAAMEEAIQAAEQTARSHDSGHMDLFGGVFAEPEADVYANHRKVK 959 Query: 926 PWSDKQRLTEEKGALGFYLSGHLFSAYEKEVRRFVRTKIASLEPSWEPRSLAGIITGVRV 985 + K+RL EK LG YL+GH YE EVRRF R +I L+P+ + +++AG+I +RV Sbjct: 960 ELTLKERLKGEKDTLGLYLTGHPIDEYEGEVRRFARQRIVELKPARDTQTVAGLIVNLRV 1019 Query: 986 QMTQRG-KLVICTLDDGTGVIEATIYNELFEPFKHIIKEDELLVVSGKVSEDRFNGGLRV 1044 ++G K+ TLDD +G IEA++++E F + +++ D L+VV G+VS+D F+GGLR+ Sbjct: 1020 MKNKKGDKMGFVTLDDRSGRIEASLFSEAFAAAQSLLQTDALVVVEGEVSQDDFSGGLRL 1079 Query: 1045 AADKVMDLGAAR--IQYGVRMVVSIN--KAIDPNHLRDTLSAHRQEQGLPFVMRYQQADA 1100 A +VM L AR + +RM + + K L + + HR P + Y ADA Sbjct: 1080 RAKRVMSLEEARTGLAESLRMKLHADLLKGDRLRWLGELFNRHR--GSCPITLDYTSADA 1137 Query: 1101 ACEVVLGDAWRINPSDSLQSTLVASFGKEAVVVEY 1135 + G++WR++P+D L L FG++ V + Y Sbjct: 1138 KALLQFGESWRVDPADDLIQALRDQFGRDNVFLNY 1172 >ZdnaE [L] COG0587 DNA polymerase III, alpha subunit EcZ Escherichia coli O157:H7 EDL933 Length = 1160 Score = 1032 bits (2668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 562/1157 (48%), Positives = 764/1157 (66%), Gaps = 37/1157 (3%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 +DGL + +VK AA G ALA+TD NL +V+FY G G+KPI G D + D Sbjct: 18 IDGLAKTAPLVKKAAALGMPALAITDFTNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLL 77 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 ++ L VL N GY L ++S+A+ + +WL L GLI LS Sbjct: 78 GDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDWLIEL-----NEGLILLS 132 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAKL 180 G MGD+G+++ GN A + C + E FP ++LEL R G+ + E + +V L Sbjct: 133 GGRMGDVGRSLLRGNSALVDECVAFYEEHFPDRYFLELIRTGRPDEESYLHAAVELAEAR 192 Query: 181 GLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVELFAD 240 GLP VAT+ ++F +F AHE R I +G + + +R R ++ QQY +S+ EM ELFAD Sbjct: 193 GLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFAD 252 Query: 241 LPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELFPNE 300 +P A+ANTVEIAKRCN+ ++LG+ LP FPT D M+ +D+LV + K GLE RL LFP+E Sbjct: 253 IPEALANTVEIAKRCNVTVRLGEYFLPQFPTGD-MSTEDYLVKRAKEGLEERLAFLFPDE 311 Query: 301 AEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGSLVA 360 ER K+RP Y+ RLE E I +M FPGYFLIV +FIQW+K+NGVPVGPGRGSGAGSLVA Sbjct: 312 EERVKRRPEYDERLETELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVA 371 Query: 361 YCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVSQIA 420 Y L ITDLDPL ++LLFERFLNPERVSMPDFD+DFC E RD+VI++V D YG++AVSQI Sbjct: 372 YALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQII 431 Query: 421 TFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLENEE 480 TFGTMAAK +RDVGRVL Y F D ISKLIP PG +TLA A E EP L E E +E Sbjct: 432 TFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPG--MTLAKAFEAEPQLPEIYEADE 489 Query: 481 EVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDVEAV 540 EVK L+ +A+++EG+ RN G HAGGV+IAP K+TDF PLY V+Q+DK DVE Sbjct: 490 EVKALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYA 549 Query: 541 GLVKFDFLGLTTLTILDRAVRYI--RMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAVF 598 GLVKFDFLGL TLTI++ A+ I R D+A +PLDD+ S+++L +++T AVF Sbjct: 550 GLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVF 609 Query: 599 QLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFCKRKHG-EAFDYPDPRTE 655 QLESRGM+ ++K +PD FED+IALVAL+RPGP+ ++ +F RKHG E YPD + + Sbjct: 610 QLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQ 669 Query: 656 G-----ILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFRE 710 +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LRRAMGKKK EEMAK R +F E Sbjct: 670 HESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAE 729 Query: 711 GAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSL 770 GA KNG++ A +IFDL+EKFAGYGFNKSH+AAYAL+SY T +LKAH+PA FMAA ++ Sbjct: 730 GAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTA 789 Query: 771 AMEDTDKVKILIEDAIDICKLAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQ 830 M++T+KV L+++ + L ILPPDIN Y F V + G +I YG+GA+KG G+ Sbjct: 790 DMDNTEKVVGLVDECWRM-GLKILPPDINSGLYHFH-VNDDG----EIVYGIGAIKGVGE 843 Query: 831 NAIEAILEAR-KSGPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVN 889 IEAI+EAR K G F++LFD R D K++NRR ++ LI +GAFD RA L S+ Sbjct: 844 GPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLG 903 Query: 890 LAWESAEQAEKSA--NQVSLFGGDDSDLEA-PLEYVQVPPWSDKQRLTEEKGALGFYLSG 946 A ++A+Q K+ Q +FG + E Y PW ++ L E+ LG YL+G Sbjct: 904 DALKAADQHAKAEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTG 963 Query: 947 HLFSAYEKEVRRFV-RTKIASLEPSWEPRSL--AGIITGVRVQMTQRG-KLVICTLDDGT 1002 H + Y KE+ R+V ++ + P+ + + AG++ RV +T+RG ++ ICTLDD + Sbjct: 964 HPINQYLKEIERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRS 1023 Query: 1003 GVIEATIYNELFEPFKHIIKEDELLVVSGKVSEDRFNGGLRVAADKVMDLGAARIQYGVR 1062 G +E ++ + + ++H++++D +L+VSG+VS D F+GGL++ A +VMD+ AR +Y Sbjct: 1024 GRLEVMLFTDALDKYQHLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARG 1083 Query: 1063 MVVSI-NKAIDP---NHLRDTLSAHRQEQGLPFVMRYQQADAACEVVLGDAWRINPSDSL 1118 + +S+ ++ ID N LR +L HR +P + YQ+ADA + G WR++PSD L Sbjct: 1084 LAISLTDRQIDDQLLNRLRQSLEPHRSGT-IPVHLYYQRADARARLRFGATWRVSPSDRL 1142 Query: 1119 QSTLVASFGKEAVVVEY 1135 + L G E V +E+ Sbjct: 1143 LNDLRGLIGSEQVELEF 1159 >ECs0186 [L] COG0587 DNA polymerase III, alpha subunit Ecs Escherichia coli O157:H7 Length = 1160 Score = 1032 bits (2668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 562/1157 (48%), Positives = 764/1157 (66%), Gaps = 37/1157 (3%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 +DGL + +VK AA G ALA+TD NL +V+FY G G+KPI G D + D Sbjct: 18 IDGLAKTAPLVKKAAALGMPALAITDFTNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLL 77 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 ++ L VL N GY L ++S+A+ + +WL L GLI LS Sbjct: 78 GDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDWLIEL-----NEGLILLS 132 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAKL 180 G MGD+G+++ GN A + C + E FP ++LEL R G+ + E + +V L Sbjct: 133 GGRMGDVGRSLLRGNSALVDECVAFYEEHFPDRYFLELIRTGRPDEESYLHAAVELAEAR 192 Query: 181 GLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVELFAD 240 GLP VAT+ ++F +F AHE R I +G + + +R R ++ QQY +S+ EM ELFAD Sbjct: 193 GLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFAD 252 Query: 241 LPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELFPNE 300 +P A+ANTVEIAKRCN+ ++LG+ LP FPT D M+ +D+LV + K GLE RL LFP+E Sbjct: 253 IPEALANTVEIAKRCNVTVRLGEYFLPQFPTGD-MSTEDYLVKRAKEGLEERLAFLFPDE 311 Query: 301 AEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGSLVA 360 ER K+RP Y+ RLE E I +M FPGYFLIV +FIQW+K+NGVPVGPGRGSGAGSLVA Sbjct: 312 EERVKRRPEYDERLETELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVA 371 Query: 361 YCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVSQIA 420 Y L ITDLDPL ++LLFERFLNPERVSMPDFD+DFC E RD+VI++V D YG++AVSQI Sbjct: 372 YALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQII 431 Query: 421 TFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLENEE 480 TFGTMAAK +RDVGRVL Y F D ISKLIP PG +TLA A E EP L E E +E Sbjct: 432 TFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPG--MTLAKAFEAEPQLPEIYEADE 489 Query: 481 EVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDVEAV 540 EVK L+ +A+++EG+ RN G HAGGV+IAP K+TDF PLY V+Q+DK DVE Sbjct: 490 EVKALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYA 549 Query: 541 GLVKFDFLGLTTLTILDRAVRYI--RMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAVF 598 GLVKFDFLGL TLTI++ A+ I R D+A +PLDD+ S+++L +++T AVF Sbjct: 550 GLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVF 609 Query: 599 QLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFCKRKHG-EAFDYPDPRTE 655 QLESRGM+ ++K +PD FED+IALVAL+RPGP+ ++ +F RKHG E YPD + + Sbjct: 610 QLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQ 669 Query: 656 G-----ILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFRE 710 +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LRRAMGKKK EEMAK R +F E Sbjct: 670 HESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAE 729 Query: 711 GAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSL 770 GA KNG++ A +IFDL+EKFAGYGFNKSH+AAYAL+SY T +LKAH+PA FMAA ++ Sbjct: 730 GAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTA 789 Query: 771 AMEDTDKVKILIEDAIDICKLAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQ 830 M++T+KV L+++ + L ILPPDIN Y F V + G +I YG+GA+KG G+ Sbjct: 790 DMDNTEKVVGLVDECWRM-GLKILPPDINSGLYHFH-VNDDG----EIVYGIGAIKGVGE 843 Query: 831 NAIEAILEAR-KSGPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVN 889 IEAI+EAR K G F++LFD R D K++NRR ++ LI +GAFD RA L S+ Sbjct: 844 GPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLG 903 Query: 890 LAWESAEQAEKSA--NQVSLFGGDDSDLEA-PLEYVQVPPWSDKQRLTEEKGALGFYLSG 946 A ++A+Q K+ Q +FG + E Y PW ++ L E+ LG YL+G Sbjct: 904 DALKAADQHAKAEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTG 963 Query: 947 HLFSAYEKEVRRFV-RTKIASLEPSWEPRSL--AGIITGVRVQMTQRG-KLVICTLDDGT 1002 H + Y KE+ R+V ++ + P+ + + AG++ RV +T+RG ++ ICTLDD + Sbjct: 964 HPINQYLKEIERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRS 1023 Query: 1003 GVIEATIYNELFEPFKHIIKEDELLVVSGKVSEDRFNGGLRVAADKVMDLGAARIQYGVR 1062 G +E ++ + + ++H++++D +L+VSG+VS D F+GGL++ A +VMD+ AR +Y Sbjct: 1024 GRLEVMLFTDALDKYQHLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARG 1083 Query: 1063 MVVSI-NKAIDP---NHLRDTLSAHRQEQGLPFVMRYQQADAACEVVLGDAWRINPSDSL 1118 + +S+ ++ ID N LR +L HR +P + YQ+ADA + G WR++PSD L Sbjct: 1084 LAISLTDRQIDDQLLNRLRQSLEPHRSGT-IPVHLYYQRADARARLRFGATWRVSPSDRL 1142 Query: 1119 QSTLVASFGKEAVVVEY 1135 + L G E V +E+ Sbjct: 1143 LNDLRGLIGSEQVELEF 1159 >STM0231 [L] COG0587 DNA polymerase III, alpha subunit Sty Salmonella typhimurium LT2 Length = 1160 Score = 1029 bits (2661), Expect = 0.0, Method: Compositional matrix adjust. Identities = 556/1157 (48%), Positives = 764/1157 (66%), Gaps = 37/1157 (3%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 +DGL + +VK AA G ALA+TD NL +V+FY G G+KPI G D + N+ Sbjct: 18 IDGLAKTGPLVKKAASLGMPALAITDFTNLCGLVKFYGAGHGAGIKPIVGADFNVHNELL 77 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 ++ L VL N GY L ++S+A+ + +WL L+ GLI LS Sbjct: 78 GDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIERDWLVELK-----EGLILLS 132 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAKL 180 G MGD+G+ + GN A E C + FP ++LEL R G+ + E + +V L Sbjct: 133 GGRMGDVGRCLLRGNQALVEECVAFYEAHFPDRYFLELIRTGRQDEETYLHAAVELAEAR 192 Query: 181 GLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVELFAD 240 GLP VAT+ ++F ++F AHE R I +G + + +R R ++ QQY +S+ EM ELF+D Sbjct: 193 GLPVVATNDVRFLESDDFDAHEIRVAIHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFSD 252 Query: 241 LPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELFPNE 300 +P A+ NTVEIAKRCN+ ++LG+ LP FPT D MT +D+LV + K GLE RL LFP+E Sbjct: 253 IPEALENTVEIAKRCNVTVRLGEYFLPQFPTGD-MTTEDYLVKKAKEGLEERLAFLFPDE 311 Query: 301 AEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGSLVA 360 ER+K+RP Y+ RL+ E I +M FPGYFLIV +FIQW+K+NGVPVGPGRGSGAGSLVA Sbjct: 312 EERKKRRPEYDERLDIELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVA 371 Query: 361 YCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVSQIA 420 Y L ITDLDPL ++LLFERFLNPERVSMPDFD+DFC E RD+VI++V D YG++AVSQI Sbjct: 372 YALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQII 431 Query: 421 TFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLENEE 480 TFGTMAAK +RDVGRVL Y F D ISKL+P PG +TLA A E EP L E E +E Sbjct: 432 TFGTMAAKAVIRDVGRVLGHPYGFVDRISKLVPPDPG--MTLAKAFEAEPQLPEIYEADE 489 Query: 481 EVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDVEAV 540 EV+ L+ +A+++EG+ RN G HAGGV+IAP K+TDF PLY V+Q+DK DVE Sbjct: 490 EVRALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYA 549 Query: 541 GLVKFDFLGLTTLTILDRAVRYI--RMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAVF 598 GLVKFDFLGL TLTI++ A+ I R D+A +PLDD+ S+++L +++T AVF Sbjct: 550 GLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVF 609 Query: 599 QLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFCKRKHG-EAFDYPDPRTE 655 QLESRGM+ ++K +PD FED+IALVAL+RPGP+ ++ +F RKHG E YPD + + Sbjct: 610 QLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREELSYPDVQWQ 669 Query: 656 G-----ILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFRE 710 +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LRRAMGKKK EEMAK R +F E Sbjct: 670 HESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFEE 729 Query: 711 GAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSL 770 GA KNG+D A +IFDL+EKFAGYGFNKSH+AAYAL+SY T +LKAH+PA FMAA ++ Sbjct: 730 GAKKNGIDGELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTA 789 Query: 771 AMEDTDKVKILIEDAIDICKLAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQ 830 M++T+KV L+++ + L ILPPDIN Y F V + G +I YG+GA+KG G+ Sbjct: 790 DMDNTEKVVGLVDECWRM-GLKILPPDINSGLYHFH-VNDEG----EIVYGIGAIKGVGE 843 Query: 831 NAIEAILEAR-KSGPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVN 889 IEAI++AR + G F++LFD R D K++NRR ++ LI +GAFD RA L S+ Sbjct: 844 GPIEAIIDARNQGGYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLG 903 Query: 890 LAWESAEQAEKSA--NQVSLFGGDDSDLEA-PLEYVQVPPWSDKQRLTEEKGALGFYLSG 946 A ++A+Q K+ Q +FG + E Y PW ++ L E+ LG YL+G Sbjct: 904 DALKAADQHAKAEAIGQTDMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTG 963 Query: 947 HLFSAYEKEVRRFV-RTKIASLEPSWEPR--SLAGIITGVRVQMTQRG-KLVICTLDDGT 1002 H + Y KE+ R+V ++ + P+ + + AG++ RV +T+RG ++ ICTLDD + Sbjct: 964 HPINQYLKEIERYVGGVRLKDMHPTERGKVTTAAGLVIAARVMVTKRGNRIGICTLDDRS 1023 Query: 1003 GVIEATIYNELFEPFKHIIKEDELLVVSGKVSEDRFNGGLRVAADKVMDLGAARIQYGVR 1062 G +E ++ + + ++ ++++D +L+VSG+VS D F+GGL++ A +VMD+ AR +Y Sbjct: 1024 GRLEVMLFTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARG 1083 Query: 1063 MVVSI-NKAIDP---NHLRDTLSAHRQEQGLPFVMRYQQADAACEVVLGDAWRINPSDSL 1118 + +S+ ++ ID N LR +L HR +P + YQ+ADA + G WR++PSD L Sbjct: 1084 LAISLTDRQIDDQLLNRLRQSLEPHRSGT-IPVHLYYQRADARARLRFGATWRVSPSDRL 1142 Query: 1119 QSTLVASFGKEAVVVEY 1135 + L G E V +E+ Sbjct: 1143 LNDLRGLIGSEQVELEF 1159 >dnaE [L] COG0587 DNA polymerase III, alpha subunit Eco Escherichia coli K12 Length = 1160 Score = 1029 bits (2661), Expect = 0.0, Method: Compositional matrix adjust. Identities = 561/1157 (48%), Positives = 763/1157 (65%), Gaps = 37/1157 (3%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 +DGL + +VK AA G ALA+TD NL +V+FY G G+KPI G D + D Sbjct: 18 IDGLAKTAPLVKKAAALGMPALAITDFTNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLL 77 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 ++ L VL N GY L ++S+A+ + +WL L GLI LS Sbjct: 78 GDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDWLIEL-----NEGLILLS 132 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAKL 180 G MGD+G+++ GN A + C + E FP ++LEL R G+ + E + +V L Sbjct: 133 GGRMGDVGRSLLRGNSALVDECVAFYEEHFPDRYFLELIRTGRPDEESYLHAAVELAEAR 192 Query: 181 GLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVELFAD 240 GLP VAT+ ++F +F AHE R I +G + + +R R ++ QQY +S+ EM ELFAD Sbjct: 193 GLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFAD 252 Query: 241 LPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELFPNE 300 +P A+ANTVEIAKRCN+ ++LG+ LP FPT D M+ +D+LV + K GLE RL LFP+E Sbjct: 253 IPEALANTVEIAKRCNVTVRLGEYFLPQFPTGD-MSTEDYLVKRAKEGLEERLAFLFPDE 311 Query: 301 AEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGSLVA 360 ER K+RP Y+ RLE E I +M FPGYFLIV +FIQW+K+NGVPVGPGRGSGAGSLVA Sbjct: 312 EERLKRRPEYDERLETELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVA 371 Query: 361 YCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVSQIA 420 Y L ITDLDPL ++LLFERFLNPERVSMPDFD+DFC E RD+VI++V D YG++AVSQI Sbjct: 372 YALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQII 431 Query: 421 TFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLENEE 480 TFGTMAAK +RDVGRVL Y F D ISKLIP PG +TLA A E EP L E E +E Sbjct: 432 TFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPG--MTLAKAFEAEPQLPEIYEADE 489 Query: 481 EVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDVEAV 540 EVK L+ +A+++EG+ RN G HAGGV+IAP K+TDF PLY V+Q+DK DVE Sbjct: 490 EVKALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYA 549 Query: 541 GLVKFDFLGLTTLTILDRAVRYI--RMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAVF 598 GLVKFDFLGL TLTI++ A+ I R D+A +PLDD+ S+++L +++T AVF Sbjct: 550 GLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVF 609 Query: 599 QLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFCKRKHG-EAFDYPDPRTE 655 QLESRGM+ ++K +PD FED+IALVAL+RPGP+ ++ +F RKHG E YPD + + Sbjct: 610 QLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQ 669 Query: 656 G-----ILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFRE 710 +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LRRAMGKKK EEMAK R +F E Sbjct: 670 HESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAE 729 Query: 711 GAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSL 770 GA KNG++ A +IFDL+EKFAGYGFNKSH+AAYAL+SY T +LKAH+PA FMAA ++ Sbjct: 730 GAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTA 789 Query: 771 AMEDTDKVKILIEDAIDICKLAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQ 830 M++T+KV L+++ + L ILPPDIN Y F V + G +I YG+GA+KG G+ Sbjct: 790 DMDNTEKVVGLVDECWRM-GLKILPPDINSGLYHFH-VNDDG----EIVYGIGAIKGVGE 843 Query: 831 NAIEAILEAR-KSGPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVN 889 IEAI+EAR K G F++LFD R D K++NRR ++ LI +GAFD RA L S+ Sbjct: 844 GPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLG 903 Query: 890 LAWESAEQAEKSA--NQVSLFGGDDSDLEA-PLEYVQVPPWSDKQRLTEEKGALGFYLSG 946 A ++A+Q K+ Q +FG + E Y PW ++ L E+ LG YL+G Sbjct: 904 DALKAADQHAKAEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTG 963 Query: 947 HLFSAYEKEVRRFV-RTKIASLEPSWEPRSL--AGIITGVRVQMTQRG-KLVICTLDDGT 1002 H + Y KE+ R+V ++ + P+ + + AG++ RV +T+RG ++ ICTLDD + Sbjct: 964 HPINQYLKEIERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRS 1023 Query: 1003 GVIEATIYNELFEPFKHIIKEDELLVVSGKVSEDRFNGGLRVAADKVMDLGAARIQYGVR 1062 G +E ++ + + ++ ++++D +L+VSG+VS D F+GGL++ A +VMD+ AR +Y Sbjct: 1024 GRLEVMLFTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARG 1083 Query: 1063 MVVSI-NKAIDP---NHLRDTLSAHRQEQGLPFVMRYQQADAACEVVLGDAWRINPSDSL 1118 + +S+ ++ ID N LR +L HR +P + YQ+ADA + G WR++PSD L Sbjct: 1084 LAISLTDRQIDDQLLNRLRQSLEPHRSGT-IPVHLYYQRADARARLRFGATWRVSPSDRL 1142 Query: 1119 QSTLVASFGKEAVVVEY 1135 + L G E V +E+ Sbjct: 1143 LNDLRGLIGSEQVELEF 1159 >YPO1059 [L] COG0587 DNA polymerase III, alpha subunit Ype Yersinia pestis Length = 1171 Score = 1025 bits (2650), Expect = 0.0, Method: Compositional matrix adjust. Identities = 548/1157 (47%), Positives = 766/1157 (66%), Gaps = 37/1157 (3%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 +DGL +I +VK AA G ALA+TD NL +V+FY A G G+KPI G D ++ ++ Sbjct: 29 IDGLAKIGPLVKRAAALGMPALAITDFTNLCGLVKFYGSAHGAGIKPIIGADFYVQSEIL 88 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 ++ L VL +N GY L ++S+A+ + +WL ++H+EG LI LS Sbjct: 89 GDELAHLTVLARNNEGYQNLTLLISEAYQRGYGAAGPIIDRDWL--IKHKEG---LILLS 143 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAKL 180 G MGD+G+ + GN Q + C + E FP +YLEL R G+ + E + +VAL + Sbjct: 144 GGRMGDVGKFLLRGNQVQVDQCLAFYQEHFPDCYYLELIRTGRPDEENYLHAAVALATER 203 Query: 181 GLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVELFAD 240 GLP VAT+ ++F +F AHE R I +G + + +R + ++ QQ+ + + +M ELFAD Sbjct: 204 GLPVVATNDVRFIDESDFDAHEIRVAIHDGFTLVDPKRPKNYSPQQFMRDEEQMCELFAD 263 Query: 241 LPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELFPNE 300 +P A+ N+VEIAKRCN+ ++LG+ LP FPT + M+ +DFLV + K GLE RL+ LFP+ Sbjct: 264 IPEALINSVEIAKRCNVTIRLGEYFLPQFPTGE-MSTEDFLVEKAKQGLEERLEFLFPDP 322 Query: 301 AEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGSLVA 360 R ++RP Y+ RL+ E I +M FPGYFLIV +FIQW+K+NGVPVGPGRGSGAGSLVA Sbjct: 323 EVRLQKRPEYDERLDIELKVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVA 382 Query: 361 YCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVSQIA 420 Y L ITD+DPL ++LLFERFLNPERVSMPDFD+DFC E RD VI++V + YG++AVSQI Sbjct: 383 YALKITDIDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDLVIEHVAEMYGRDAVSQII 442 Query: 421 TFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLENEE 480 TFGTMAAK +RDVGRVL Y F D ISKLIP PG +TL A EP L E E +E Sbjct: 443 TFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPLDPG--MTLEKAFAAEPQLAEIYEADE 500 Query: 481 EVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDVEAV 540 EV+ L+ +A+++EG+ RN G HAGGV+IAP K+TDF PLY + V+Q+DK+DVE Sbjct: 501 EVRALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDAEGNNPVTQFDKNDVEYA 560 Query: 541 GLVKFDFLGLTTLTILDRAVRYI--RMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAVF 598 GLVKFDFLGL TLTI++ A+ I R + D+A +PL+D+ S+++L +++T AVF Sbjct: 561 GLVKFDFLGLRTLTIINWALEMINARRAKTGLEPIDIASIPLEDKKSFDMLQRSETTAVF 620 Query: 599 QLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFCKRKHG-EAFDYPD---- 651 QLESRGM+ ++K +PD FED+IALVAL+RPGP+ ++ +F RKHG EA YPD Sbjct: 621 QLESRGMKDLIKRLKPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREAISYPDIEWQ 680 Query: 652 -PRTEGILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFRE 710 + +L TYGI++YQEQVMQ+AQV+ GYSLGGAD+LRRAMGKK EMAK R +F + Sbjct: 681 HESLKPVLEPTYGIILYQEQVMQIAQVLSGYSLGGADMLRRAMGKKNPAEMAKQRSVFED 740 Query: 711 GAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSL 770 GA G+D A +IFDL+EKFAGYGFNKSH+AAYAL+SY T +LKAH+PA FMAA ++ Sbjct: 741 GAKNQGIDGELAIKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTA 800 Query: 771 AMEDTDKVKILIEDAIDICKLAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQ 830 M++TDKV L+++ + L ILPPDIN Y F V + G +I YG+GA+KG G+ Sbjct: 801 DMDNTDKVVGLVDECWRM-GLKILPPDINSGLYHFH-VNDDG----EIVYGIGAIKGVGE 854 Query: 831 NAIEAILEARKSGP-FKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVN 889 IEAILEARK G FK+LFD RVD K++N+R ++ LI +GAFD RA L +S+ Sbjct: 855 GPIEAILEARKEGGYFKELFDLCARVDTKKLNKRILEKLIMSGAFDRLGPHRAALMSSLG 914 Query: 890 LAWESAEQAEKSA--NQVSLFGG-DDSDLEAPLEYVQVPPWSDKQRLTEEKGALGFYLSG 946 A ++A+Q K+ QV +FG D+ + Y VPPW ++ L E+ LG YL+G Sbjct: 915 DALKAADQHAKAEAIGQVDMFGVLADAPEQVEQSYANVPPWQEQVVLDGERETLGLYLTG 974 Query: 947 HLFSAYEKEVRRFV-RTKIASLEPSWEPR--SLAGIITGVRVQMTQRGKLV-ICTLDDGT 1002 H + Y KE+ R+ ++ + P+ + + G++ RV +T+RG + ICTLDD + Sbjct: 975 HPITQYLKEIERYAGGMRLKDMHPTDRGKMTTAVGLVIAARVMVTKRGNRIGICTLDDRS 1034 Query: 1003 GVIEATIYNELFEPFKHIIKEDELLVVSGKVSEDRFNGGLRVAADKVMDLGAARIQYGVR 1062 G +E ++ + E ++H++++D +L+ +G+VS D F+GGL++ A ++MD+ AR +Y Sbjct: 1035 GRLEVMLFTDALEKYQHLLEKDRILIATGQVSFDDFSGGLKMTARELMDISEAREKYASG 1094 Query: 1063 MVVSI-NKAIDP---NHLRDTLSAHRQEQGLPFVMRYQQADAACEVVLGDAWRINPSDSL 1118 + +S+ ++ ID N LR +L HR +P + YQ+ DA + G WR+ P+D L Sbjct: 1095 LAISLTDRQIDDQLLNRLRQSLEPHRAGT-IPVHLYYQREDARARLRFGATWRVTPTDRL 1153 Query: 1119 QSTLVASFGKEAVVVEY 1135 L G E V +E+ Sbjct: 1154 LIDLRTLVGNEQVELEF 1170 >VC2245 [L] COG0587 DNA polymerase III, alpha subunit Vch Vibrio cholerae Length = 1164 Score = 1018 bits (2633), Expect = 0.0, Method: Compositional matrix adjust. Identities = 558/1156 (48%), Positives = 763/1156 (66%), Gaps = 36/1156 (3%) Query: 1 VDGLVRIDDIVKAAAKDGQAALAVTDLANLFCMVRFYKEARGKGVKPIAGCDLWITNDAD 60 VDGL ++ +VK A G A+A+TD NL +V+FY A GVKPI G D + ++ Sbjct: 23 VDGLSKVPPLVKKVAAMGMPAMALTDFTNLCGLVKFYSTAHNCGVKPIIGADFTLQSEEF 82 Query: 61 REKPFRLLVLIKNRHGYLQLCEVLSQAWLNNQYKGRAEVRMEWLDALRHQEGGNGLIALS 120 ++ +L +L KN GY L ++S+A+L + + + WL + H EG LI LS Sbjct: 83 GDELTKLTLLAKNNVGYKNLTLLISKAYLRGHVQHQPVIDKAWL--VEHAEG---LIVLS 137 Query: 121 GAAMGDIGQAIDNGNLAQAEACARRWAEIFPGAFYLELQRAGQANMEVQVRQSVALGAKL 180 G G++G+A+ GN Q E C + F FYLEL R G+A+ E + ++ + + Sbjct: 138 GGKSGEVGRALLKGNQQQVERCIEFYQTHFADHFYLELIRTGRADEESYLHFALDVAEQY 197 Query: 181 GLPCVATHPIQFQSPEEFIAHEARTCIAEGEIMANARRVRRFNEQQYFKSQAEMVELFAD 240 LP VAT+ + F + E F AHE R I +G + + RR + ++ +QY +S+AEM ELFAD Sbjct: 198 DLPVVATNEVVFITEESFEAHEIRVAIHDGYTLEDPRRPKNYSPKQYLRSEAEMCELFAD 257 Query: 241 LPGAVANTVEIAKRCNLVLQLGKPQLPDFPTPDGMTIDDFLVAQTKAGLEVRLKELFPNE 300 +P A+AN+VEIAKRCN+ ++LG+ LP+FPT GM I+DFLV +++ GLE RL+ LFP+ Sbjct: 258 IPEALANSVEIAKRCNVTVRLGEYFLPNFPT-GGMAIEDFLVMKSREGLEERLEFLFPDP 316 Query: 301 AEREKQRPRYEARLEFENNTIIKMKFPGYFLIVADFIQWAKNNGVPVGPGRGSGAGSLVA 360 R K+RP Y+ RL+ E + I +M FPGYFLIV +FIQW+K+N +PVGPGRGSGAGSLVA Sbjct: 317 EVRAKRRPEYDERLQVELDVINQMGFPGYFLIVMEFIQWSKDNDIPVGPGRGSGAGSLVA 376 Query: 361 YCLLITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQEGRDRVIQYVKDRYGKEAVSQIA 420 Y L ITDLDPL Y+LLFERFLNPERVSMPDFD+DFC + RD+VI +V + YG++AVSQI Sbjct: 377 YALKITDLDPLEYDLLFERFLNPERVSMPDFDVDFCMDKRDQVIDHVAEMYGRDAVSQII 436 Query: 421 TFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLADAIEEEPLLKERLENEE 480 TFGTMAAK +RDVGRVL + F D ISKL+P PG +TL A EP L+E + +E Sbjct: 437 TFGTMAAKAVIRDVGRVLGHPFGFVDRISKLVPPDPG--MTLEKAFIAEPALQELYDADE 494 Query: 481 EVKQLMGLAQQVEGIARNIGMHAGGVLIAPGKLTDFCPLYTQGGDSGVVSQYDKDDVEAV 540 EVK+L+ + +EG RN G HAGGV+I+P +TDF P+Y + V+Q+DK+DVE Sbjct: 495 EVKELIDKCRILEGCTRNAGKHAGGVVISPTAITDFAPIYCDAEGNFPVTQFDKNDVETA 554 Query: 541 GLVKFDFLGLTTLTILDRAVRYI--RMLDPAMADFDLAKLPLDDRPSYELLTKAKTVAVF 598 GLVKFDFLGL TLTI+D A+ + R+ + +PLDD S+ L AKT AVF Sbjct: 555 GLVKFDFLGLRTLTIIDWALGLVNPRLKKAGKPPVRIEAIPLDDARSFRNLQDAKTTAVF 614 Query: 599 QLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFCKRKHG-EAFDYPDPRTE 655 QLESRGM+ ++K +PD FEDIIALVAL+RPGP+ ++ +F RKHG EA YPD + + Sbjct: 615 QLESRGMKELIKRLQPDCFEDIIALVALFRPGPLQSGMVDNFIDRKHGREAISYPDEKWQ 674 Query: 656 G-----ILSETYGIMVYQEQVMQMAQVIGGYSLGGADLLRRAMGKKKAEEMAKHRELFRE 710 IL TYGI++YQEQVMQ+AQV+ GY+LGGAD+LRRAMGKKK EEMAK R +F+E Sbjct: 675 HESLKEILEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRAVFQE 734 Query: 711 GAAKNGLDQAKADEIFDLMEKFAGYGFNKSHAAAYALLSYYTAYLKAHHPAAFMAANLSL 770 GA KNG+D A +IFDL+EKFAGYGFNKSH+AAYAL+SY T +LK H+PA FMAA ++ Sbjct: 735 GAEKNGVDGELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKTHYPAEFMAAVMTA 794 Query: 771 AMEDTDKVKILIEDAIDICKLAILPPDINKSDYRFMPVGEPGKKATQIRYGLGAVKGAGQ 830 M++T+KV L+++ ++ L +LPPDIN YRF V + G I YG+GA+KG G+ Sbjct: 795 DMDNTEKVVGLVDECKNM-GLTVLPPDINSGLYRF-NVDDNGA----IVYGIGAIKGVGE 848 Query: 831 NAIEAILEAR-KSGPFKDLFDFAKRVDKKQINRRTIDSLIRAGAFDCFKVDRAVLQASVN 889 IEAILEAR K G FKDLFDF R+D K++N+R I+ LI AGA D RA + ASV+ Sbjct: 849 GPIEAILEARNKGGYFKDLFDFCARIDLKKVNKRVIEKLILAGALDRLGPHRAAMMASVD 908 Query: 890 LAWESAEQAEKSA--NQVSLFGG-DDSDLEAPLEYVQVPPWSDKQRLTEEKGALGFYLSG 946 A +A Q ++ Q +FG D+ E +Y QVP W +K RL E+ LG YL+G Sbjct: 909 DAVRAASQHHQAEAFGQADMFGVLTDAPEEVEQKYTQVPEWPEKVRLEGERETLGLYLTG 968 Query: 947 HLFSAYEKEVRRFVRTKIASLEPSWEPRSL--AGIITGVRVQMTQRG-KLVICTLDDGTG 1003 H Y KE+ ++ ++ P+ +SL AG++ RV T+RG ++ + TLDD +G Sbjct: 969 HPVDEYLKELTKYTSCRLNEAAPTRRDQSLTVAGLVIAARVMTTKRGTRIGLMTLDDRSG 1028 Query: 1004 VIEATIYNELFEPFKHIIKEDELLVVSGKVSEDRFNGGLRVAADKVMDLGAARIQYGVRM 1063 +E +Y+E + + +++D++LVVSG+VS D FNGGL+++A +VMDLG+AR ++ + Sbjct: 1029 RMEVMLYSEALDRYAEWLEKDKILVVSGQVSFDDFNGGLKMSAREVMDLGSAREKFARGL 1088 Query: 1064 VVSINKA-IDPN---HLRDTLSAHRQEQGLPFVMRYQQADAACEVVLGDAWRINPSDSLQ 1119 +SI ++ ID L HR +P + YQ+ DA + LG WR+ PSD+L Sbjct: 1089 SISILQSQIDQQFFERFSHILEPHRAGT-VPVNVYYQRPDARARLTLGTEWRVTPSDTLL 1147 Query: 1120 STLVASFGKEAVVVEY 1135 L G + V +E+ Sbjct: 1148 DELKQLLGHDQVELEF 1163