BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0003.p (161 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0712 [H] COG0054 Riboflavin synthase beta-chain Rso Ralstonia... 212 3e-55 NMB0684 [H] COG0054 Riboflavin synthase beta-chain Nme Neisseria... 190 1e-48 NMA0886 [H] COG0054 Riboflavin synthase beta-chain NmA Neisseria... 190 1e-48 CAC0593 [H] COG0054 Riboflavin synthase beta-chain Cac Clostridi... 120 1e-27 SP0175 [H] COG0054 Riboflavin synthase beta-chain Spn Streptococ... 120 1e-27 HI1303 [H] COG0054 Riboflavin synthase beta-chain Hin Haemophilu... 117 8e-27 PM0731 [H] COG0054 Riboflavin synthase beta-chain Pmu Pasteurell... 116 2e-26 BS_ribH [H] COG0054 Riboflavin synthase beta-chain Bsu Bacillus ... 116 2e-26 TM1825 [H] COG0054 Riboflavin synthase beta-chain Tma Thermotoga... 116 2e-26 FN1505 [H] COG0054 Riboflavin synthase beta-chain Fnu Fusobacter... 115 3e-26 >RSc0712 [H] COG0054 Riboflavin synthase beta-chain Rso Ralstonia solanacearum Length = 164 Score = 212 bits (539), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 112/164 (68%), Positives = 124/164 (75%), Gaps = 3/164 (1%) Query: 1 MTIGTYDPDFNGESLRIGIVQARFNEDVCHGLLAACLAELKHLGVADEDILHVTVPGALE 60 M G Y + GE LRIGIVQARFNE VC L AC+AEL+ LGVA ED+L VTVPGALE Sbjct: 1 MDHGFYPTNLEGEGLRIGIVQARFNEPVCEALREACVAELEQLGVAGEDVLLVTVPGALE 60 Query: 61 IPLALQKMAETEQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTT 120 +PLALQKMAE+ QFDALIALGAVIRGETYHFELVSNESGAGITR+ LDF + IAN +LTT Sbjct: 61 VPLALQKMAESGQFDALIALGAVIRGETYHFELVSNESGAGITRVCLDFNIAIANGILTT 120 Query: 121 ENDEQAEVRMAEKGADAARVAVEMANLAIVLEEL---GQVTEEE 161 + D QA R EKG D AR A+EMANL L+ L GQ E E Sbjct: 121 DTDAQAHARTREKGRDCARTAIEMANLTAALDGLQDHGQDDENE 164 >NMB0684 [H] COG0054 Riboflavin synthase beta-chain Nme Neisseria meningitidis MC58 Length = 158 Score = 190 bits (483), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 98/160 (61%), Positives = 122/160 (76%), Gaps = 3/160 (1%) Query: 3 IGTYDPDFNGESLRIGIVQARFNEDVCHGLLAACLAELKHLGVADEDILHVTVPGALEIP 62 + T P+ +G+ LRIGIVQARF ++ +L C L+ LGVADE+I TVPGALEIP Sbjct: 1 MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIP 60 Query: 63 LALQKMAETEQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTTEN 122 +AL A +E+FDALIA+G VIRGETYHFELVSNESGAG++R+ LD+ +PIANAVLTTEN Sbjct: 61 IALMNFASSEKFDALIAIGVVIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTEN 120 Query: 123 DEQAEVRMAEKGADAARVAVEMANLA-IVLEELGQVTEEE 161 D QA R+ EK +DAA+VAVE ANL ++LEE Q +EE Sbjct: 121 DAQAIERIEEKASDAAKVAVECANLVNLLLEE--QFEDEE 158 >NMA0886 [H] COG0054 Riboflavin synthase beta-chain NmA Neisseria meningitidis Z2491 Length = 158 Score = 190 bits (483), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 98/160 (61%), Positives = 122/160 (76%), Gaps = 3/160 (1%) Query: 3 IGTYDPDFNGESLRIGIVQARFNEDVCHGLLAACLAELKHLGVADEDILHVTVPGALEIP 62 + T P+ +G+ LRIGIVQARF ++ +L C L+ LGVADE+I TVPGALEIP Sbjct: 1 MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIP 60 Query: 63 LALQKMAETEQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTTEN 122 +AL A +E+FDALIA+G VIRGETYHFELVSNESGAG++R+ LD+ +PIANAVLTTEN Sbjct: 61 IALMNFASSEKFDALIAIGVVIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTEN 120 Query: 123 DEQAEVRMAEKGADAARVAVEMANLA-IVLEELGQVTEEE 161 D QA R+ EK +DAA+VAVE ANL ++LEE Q +EE Sbjct: 121 DAQAIERIEEKASDAAKVAVECANLVNLLLEE--QFEDEE 158 >CAC0593 [H] COG0054 Riboflavin synthase beta-chain Cac Clostridium acetobutylicum Length = 155 Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 67/146 (45%), Positives = 87/146 (59%), Gaps = 4/146 (2%) Query: 6 YDPDFNGESLRIGIVQARFNEDVCHGLLAACLAELKHLGVADEDILHVTVPGALEIPLAL 65 Y+ ++L+ GIV RFNE + LL+ + LK G ++ I PGA EIPL Sbjct: 4 YEGKLISKNLKFGIVAGRFNEFIVSKLLSGAVDALKRHGCDEDSIELAWAPGAFEIPLIS 63 Query: 66 QKMAETEQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTTENDEQ 125 QKMAE+ ++DA+I LGAVIRG T HF+ VS+E GI + L G P+ VLTT+N EQ Sbjct: 64 QKMAESGKYDAVICLGAVIRGATSHFDYVSSEVSKGIAQTSLKTGCPVIFGVLTTDNIEQ 123 Query: 126 ----AEVRMAEKGADAARVAVEMANL 147 A + KG DAA A+EMANL Sbjct: 124 AIERAGTKSGNKGFDAAVTAIEMANL 149 >SP0175 [H] COG0054 Riboflavin synthase beta-chain Spn Streptococcus pneumoniae TIGR4 Length = 155 Score = 120 bits (301), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 65/154 (42%), Positives = 95/154 (61%), Gaps = 4/154 (2%) Query: 3 IGTYDPDFNGESLRIGIVQARFNEDVCHGLLAACLAELKHLGVADEDILHVTVPGALEIP 62 + TY+ + +++IGIV ARFNE + LL+ L LK V ++DI VPGA EIP Sbjct: 1 MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVNEKDIEVAWVPGAFEIP 60 Query: 63 LALQKMAETEQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTTEN 122 L KMA+++++DA+I LGAVIRG T H++ V +E GI +I L+ +P+ VLTT+ Sbjct: 61 LIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQISLNSEIPVMFGVLTTDT 120 Query: 123 DEQ----AEVRMAEKGADAARVAVEMANLAIVLE 152 EQ A + KG++ A+ A+EM NL L+ Sbjct: 121 IEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLD 154 >HI1303 [H] COG0054 Riboflavin synthase beta-chain Hin Haemophilus influenzae Length = 173 Score = 117 bits (294), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 62/137 (45%), Positives = 90/137 (65%), Gaps = 5/137 (3%) Query: 16 RIGIVQARFNEDVCHGLLAACLAELKHLG-VADEDILHVTVPGALEIPLALQKMAETEQF 74 ++ +V ARFN + LL + LK +G V DE+I V PGA E+PL +++AE+++F Sbjct: 30 KVAVVIARFNSFINESLLEGAIDALKRIGQVKDENITIVRTPGAYELPLVARRLAESKKF 89 Query: 75 DALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTTENDEQ----AEVRM 130 DA++ALG VIRG T HFE V+ E+ +G+ ++ +D +P+A VLTTEN EQ A + Sbjct: 90 DAIVALGTVIRGGTAHFEYVAGEASSGLGKVAMDAEIPVAFGVLTTENIEQAIERAGTKA 149 Query: 131 AEKGADAARVAVEMANL 147 KGA+AA A+EM NL Sbjct: 150 GNKGAEAALTALEMVNL 166 >PM0731 [H] COG0054 Riboflavin synthase beta-chain Pmu Pasteurella multocida Length = 157 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 63/137 (45%), Positives = 91/137 (66%), Gaps = 5/137 (3%) Query: 16 RIGIVQARFNEDVCHGLLAACLAELKHLG-VADEDILHVTVPGALEIPLALQKMAETEQF 74 +I +V ARFN + LL L LK LG V +E+I V VPGA E+PL +++AE++++ Sbjct: 14 KIAVVIARFNSFINESLLEGALDALKRLGQVKEENITLVRVPGAYELPLVARRLAESKKY 73 Query: 75 DALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTTENDEQ----AEVRM 130 D ++ALG VIRG T HFE V+ E+ +G+ ++ ++ +P+A VLTTEN EQ A + Sbjct: 74 DGIVALGTVIRGGTAHFEYVAGEASSGLGQVAMNADIPVAFGVLTTENIEQAIERAGTKA 133 Query: 131 AEKGADAARVAVEMANL 147 KGA+AA VA+EM NL Sbjct: 134 GNKGAEAALVALEMVNL 150 >BS_ribH [H] COG0054 Riboflavin synthase beta-chain Bsu Bacillus subtilis Length = 154 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 65/140 (46%), Positives = 83/140 (59%), Gaps = 4/140 (2%) Query: 12 GESLRIGIVQARFNEDVCHGLLAACLAELKHLGVADEDILHVTVPGALEIPLALQKMAET 71 G L+IGIV RFN+ + LL+ L GV DI VPGA EIP A +KMAET Sbjct: 10 GTGLKIGIVVGRFNDFITSKLLSGAEDALLRHGVDTNDIDVAWVPGAFEIPFAAKKMAET 69 Query: 72 EQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTTENDEQ----AE 127 +++DA+I LG VIRG T H++ V NE+ GI + GVP+ ++TTEN EQ A Sbjct: 70 KKYDAIITLGTVIRGATTHYDYVCNEAAKGIAQAANTTGVPVIFGIVTTENIEQAIERAG 129 Query: 128 VRMAEKGADAARVAVEMANL 147 + KG D A A+EMANL Sbjct: 130 TKAGNKGVDCAVSAIEMANL 149 >TM1825 [H] COG0054 Riboflavin synthase beta-chain Tma Thermotoga maritima Length = 165 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 65/143 (45%), Positives = 88/143 (61%), Gaps = 4/143 (2%) Query: 9 DFNGESLRIGIVQARFNEDVCHGLLAACLAELKHLGVADEDILHVTVPGALEIPLALQKM 68 D+ GE L+I +V RFN+ V LL L LK GV+DE+I V +PG++E L+++ Sbjct: 7 DYRGEGLKIAVVVPRFNDLVTSKLLEGALDGLKRHGVSDENITVVRIPGSMEAIYTLKRL 66 Query: 69 AETEQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTTENDEQAEV 128 + DA+I LGAVIRGETYHF +V+NE G + + + +PI VLTT+ EQA Sbjct: 67 LDLGVHDAIIVLGAVIRGETYHFNVVANEIGKAVAQFNMTSDIPIVFGVLTTDTLEQALN 126 Query: 129 R----MAEKGADAARVAVEMANL 147 R KG +AA VA+EMANL Sbjct: 127 RAGAKSGNKGFEAAMVAIEMANL 149 >FN1505 [H] COG0054 Riboflavin synthase beta-chain Fnu Fusobacterium nucleatum Length = 157 Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 64/146 (43%), Positives = 88/146 (60%), Gaps = 4/146 (2%) Query: 6 YDPDFNGESLRIGIVQARFNEDVCHGLLAACLAELKHLGVADEDILHVTVPGALEIPLAL 65 ++ FNG+ +I IV ARFNE + L+ LK V D+DI VPGA EIPL Sbjct: 8 FEGKFNGKGTKIAIVAARFNEFITSKLIGGAEDILKRHEVQDDDINLFWVPGAFEIPLIA 67 Query: 66 QKMAETEQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGVPIANAVLTT----E 121 +K+A+++++DA+I LGAVI+G T HF+ V E G+ + L+ VP+ VLTT E Sbjct: 68 KKLAQSKKYDAVITLGAVIKGSTPHFDYVCAEVSKGVAHVSLESEVPVIFGVLTTNSIEE 127 Query: 122 NDEQAEVRMAEKGADAARVAVEMANL 147 E+A + KGADAA A+EM NL Sbjct: 128 AIERAGTKAGNKGADAAMTAIEMINL 153