BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0242.p (142 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0529 [R] COG0319 Predicted metal-dependent hydrolase Rso Rals... 166 1e-41 XF0903 [R] COG0319 Predicted metal-dependent hydrolase Xfa Xylel... 122 2e-28 STM0668 [R] COG0319 Predicted metal-dependent hydrolase Sty Salm... 122 3e-28 PA3982 [R] COG0319 Predicted metal-dependent hydrolase Pae Pseud... 120 1e-27 HI0004 [R] COG0319 Predicted metal-dependent hydrolase Hin Haemo... 119 2e-27 PM1045 [R] COG0319 Predicted metal-dependent hydrolase Pmu Paste... 119 3e-27 VC0960 [R] COG0319 Predicted metal-dependent hydrolase Vch Vibri... 115 3e-26 YPO2618 [R] COG0319 Predicted metal-dependent hydrolase Ype Yers... 115 3e-26 NMA0717 [R] COG0319 Predicted metal-dependent hydrolase NmA Neis... 111 5e-25 NMB0538 [R] COG0319 Predicted metal-dependent hydrolase Nme Neis... 110 1e-24 >RSc0529 [R] COG0319 Predicted metal-dependent hydrolase Rso Ralstonia solanacearum Length = 255 Score = 166 bits (420), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 78/123 (63%), Positives = 93/123 (75%), Gaps = 1/123 (0%) Query: 20 WVQAALFAPAQLTLRFVGSEEGRDLNRDYRGKDYATNVLTFAYTEDEDSEVTEADIIFCT 79 W+ ALFA AQL +RFV EEGR LN YRGKDYATNVLTF+Y E ED V ADI+ C Sbjct: 134 WIAPALFADAQLNVRFVDEEEGRTLNHTYRGKDYATNVLTFSYAETEDDPVA-ADIVLCC 192 Query: 80 DVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYDHEDDEEADEMEALETEILAGLGYANPY 139 V+E+EA +Q K + H AHL+VHG LHAQGYDHED +A+EME +ETE+LAGLG+ +PY Sbjct: 193 PVVEQEAKDQGKPLRAHYAHLIVHGALHAQGYDHEDPAQAEEMEGIETEVLAGLGFPDPY 252 Query: 140 AAR 142 A R Sbjct: 253 ADR 255 >XF0903 [R] COG0319 Predicted metal-dependent hydrolase Xfa Xylella fastidiosa 9a5c Length = 161 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 68/147 (46%), Positives = 83/147 (56%), Gaps = 9/147 (6%) Query: 1 VQYADERLKKTITTTLLRRWVQAAL---FAPAQLTLRFVGSEEGRDLNRDYRGKDYATNV 57 + Y R K + R+WV A L A L +R V +EGR LN YR KDYATNV Sbjct: 12 ISYGLPRTKLPAAVSF-RKWVAATLQGRIRKADLAIRIVDEKEGRALNYHYRNKDYATNV 70 Query: 58 LTFAYTEDEDSE-----VTEADIIFCTDVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYD 112 L+F E DI+ C V+ +EAAEQ KS+ H AHL VHG LH G++ Sbjct: 71 LSFPAQLPEPLPKALKIPLLGDIVMCAPVIAREAAEQGKSLSAHYAHLTVHGTLHLLGWN 130 Query: 113 HEDDEEADEMEALETEILAGLGYANPY 139 HED +EAD ME LE EILA LG ++PY Sbjct: 131 HEDHQEADAMEQLEREILANLGISDPY 157 >STM0668 [R] COG0319 Predicted metal-dependent hydrolase Sty Salmonella typhimurium LT2 Length = 157 Score = 122 bits (305), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 4/129 (3%) Query: 17 LRRWVQAALFA---PAQLTLRFVGSEEGRDLNRDYRGKDYATNVLTFAYTEDEDSEVTE- 72 +RW+ + A++T+R V E DLN YRGKD TNVL+F + E+ Sbjct: 24 FQRWLDGVIPQFQEEAEVTIRLVDEAESHDLNLTYRGKDKPTNVLSFPFEAPAGIEMPLL 83 Query: 73 ADIIFCTDVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYDHEDDEEADEMEALETEILAG 132 D+I C V+E+EA EQ K +E H AH+VVHG LH GYDH DD+EA+EME+LETEI+ Sbjct: 84 GDLIICRQVVEQEAQEQSKPLEAHWAHMVVHGSLHLLGYDHIDDDEAEEMESLETEIMLA 143 Query: 133 LGYANPYAA 141 +GY +PY A Sbjct: 144 MGYEDPYIA 152 >PA3982 [R] COG0319 Predicted metal-dependent hydrolase Pae Pseudomonas aeruginosa Length = 160 Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 64/129 (49%), Positives = 84/129 (65%), Gaps = 4/129 (3%) Query: 17 LRRWVQAALF--APAQLTLRFVGSEEGRDLNRDYRGKDYATNVLTF-AYTEDEDSEVTE- 72 R W + AL ++LT+R V EG +LN YR KDYATNVL+F A DE ++ Sbjct: 22 FRAWCELALRQRPESELTIRLVDEAEGLELNSTYRHKDYATNVLSFPADVPDELLDIPLL 81 Query: 73 ADIIFCTDVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYDHEDDEEADEMEALETEILAG 132 D++ C V+ +EA EQ+K ++ H AHLV+HG LH GYDH DD EA+EME LE E+LA Sbjct: 82 GDLVICAPVVAREALEQRKPLQAHWAHLVIHGCLHLLGYDHIDDAEAEEMETLERELLAE 141 Query: 133 LGYANPYAA 141 LG+ +PYA Sbjct: 142 LGHPDPYAC 150 >HI0004 [R] COG0319 Predicted metal-dependent hydrolase Hin Haemophilus influenzae Length = 154 Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 61/145 (42%), Positives = 92/145 (63%), Gaps = 4/145 (2%) Query: 1 VQYADERLKKTITTTLLRRWVQAALFAPA---QLTLRFVGSEEGRDLNRDYRGKDYATNV 57 +Q A E ++ T + +W A+ ++T+R V E +LN YRGKD TNV Sbjct: 8 LQIATENIEGLPTEEQIVQWATGAVQPEGNEVEMTVRIVDEAESHELNLTYRGKDRPTNV 67 Query: 58 LTFAYTEDEDSEVTE-ADIIFCTDVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYDHEDD 116 L+F + ++ E+ D++ C V+E+EA+EQ+K + H AH+VVHG LH GYDH +D Sbjct: 68 LSFPFECPDEVELPLLGDLVICRQVVEREASEQEKPLMAHWAHMVVHGSLHLLGYDHIED 127 Query: 117 EEADEMEALETEILAGLGYANPYAA 141 +EA+EME+LET+I+ GLG+ +PY A Sbjct: 128 DEAEEMESLETQIMQGLGFDDPYLA 152 >PM1045 [R] COG0319 Predicted metal-dependent hydrolase Pmu Pasteurella multocida Length = 158 Score = 119 bits (297), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 59/129 (45%), Positives = 83/129 (64%), Gaps = 4/129 (3%) Query: 17 LRRWVQAAL---FAPAQLTLRFVGSEEGRDLNRDYRGKDYATNVLTFAYTEDEDSEVTE- 72 ++ W A+ F+ ++T+R V E DLN YRGKD TNVL+F + ++ E++ Sbjct: 24 IQAWANRAIQPEFSDVEMTVRIVDEAESHDLNLTYRGKDKPTNVLSFPFECPDEVELSLL 83 Query: 73 ADIIFCTDVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYDHEDDEEADEMEALETEILAG 132 D++ C V+EKEA EQ K + H AH+VVHG LH GYDH +D EA+EME LETEI+ Sbjct: 84 GDLVICRQVVEKEAEEQGKPLMAHWAHMVVHGCLHLLGYDHIEDAEAEEMEGLETEIMQS 143 Query: 133 LGYANPYAA 141 LG+ +PY + Sbjct: 144 LGFDDPYLS 152 >VC0960 [R] COG0319 Predicted metal-dependent hydrolase Vch Vibrio cholerae Length = 154 Score = 115 bits (288), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 56/116 (48%), Positives = 78/116 (67%), Gaps = 1/116 (0%) Query: 27 APAQLTLRFVGSEEGRDLNRDYRGKDYATNVLTFAYTEDEDSEV-TEADIIFCTDVLEKE 85 A A++T+R V E LN +YRGKD TNVL+F + E+ D++ C V+E+E Sbjct: 36 AQAEVTVRIVDEAESHALNLNYRGKDKPTNVLSFPFEAPSGMEMDLLGDLVICRQVVERE 95 Query: 86 AAEQKKSVEEHTAHLVVHGVLHAQGYDHEDDEEADEMEALETEILAGLGYANPYAA 141 A EQ K ++ H AH+VVHG LH GYDH +D+EA+EME+LETEI+ +G+ +PY A Sbjct: 96 AIEQNKPLQAHWAHMVVHGSLHLLGYDHIEDDEAEEMESLETEIMQEMGFTDPYLA 151 >YPO2618 [R] COG0319 Predicted metal-dependent hydrolase Ype Yersinia pestis Length = 157 Score = 115 bits (288), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 66/129 (51%), Positives = 89/129 (68%), Gaps = 4/129 (3%) Query: 17 LRRWVQA--ALFAP-AQLTLRFVGSEEGRDLNRDYRGKDYATNVLTFAYTEDEDSEVTE- 72 +RW++A LF P +++T+R V E DLN YRGKD +TNVL+F + + E+ Sbjct: 24 FQRWLEAVLPLFQPVSEVTIRLVDEAESHDLNLTYRGKDKSTNVLSFPFEAPPEIELPLL 83 Query: 73 ADIIFCTDVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYDHEDDEEADEMEALETEILAG 132 D+I C V+EKEA EQ+K++ H AH+VVHG LH GYDH DDEEA+EME +ETEI+ G Sbjct: 84 GDLIICRQVVEKEAIEQEKALLAHWAHMVVHGSLHLLGYDHIDDEEAEEMELIETEIMHG 143 Query: 133 LGYANPYAA 141 LGY +PY + Sbjct: 144 LGYPDPYIS 152 >NMA0717 [R] COG0319 Predicted metal-dependent hydrolase NmA Neisseria meningitidis Z2491 Length = 171 Score = 111 bits (277), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 65/129 (50%), Positives = 83/129 (64%), Gaps = 8/129 (6%) Query: 19 RWVQAAL---FAPAQLTLRFVGSEEGRDLNRDYRGKDYATNVLTFAYTEDE--DSEVTE- 72 RW +AL + A ++L + EE R NRDYRGKDYATNVL+FA E E +V+E Sbjct: 38 RWAWSALKSGYRRADISLILLDEEEARAYNRDYRGKDYATNVLSFALNEGEILPCQVSEK 97 Query: 73 --ADIIFCTDVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYDHEDDEEADEMEALETEIL 130 D+I C V+ KEAAEQ K+ E H AHL +HGVLH GYDH +D+EA+ MEA E ++ Sbjct: 98 LYGDLIICPQVVLKEAAEQGKTPERHFAHLTIHGVLHLMGYDHIEDDEAEIMEAEEIRLM 157 Query: 131 AGLGYANPY 139 G+ NPY Sbjct: 158 LAAGFPNPY 166 >NMB0538 [R] COG0319 Predicted metal-dependent hydrolase Nme Neisseria meningitidis MC58 Length = 169 Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 64/129 (49%), Positives = 83/129 (64%), Gaps = 8/129 (6%) Query: 19 RWVQAAL---FAPAQLTLRFVGSEEGRDLNRDYRGKDYATNVLTFAYTEDE--DSEVTE- 72 RW +AL + A ++L + EE R NRDYRGKDYATNVL+FA E E +V+E Sbjct: 38 RWAWSALKNEYRRADISLILLDEEEARAYNRDYRGKDYATNVLSFALNEGEILPCQVSEK 97 Query: 73 --ADIIFCTDVLEKEAAEQKKSVEEHTAHLVVHGVLHAQGYDHEDDEEADEMEALETEIL 130 D+I C V+ KEAAEQ K+ E+H AHL +HG LH GYDH +D+EA+ MEA E ++ Sbjct: 98 LYGDLIICPQVVLKEAAEQGKTPEQHFAHLTIHGTLHLMGYDHIEDDEAEIMEAEEIRLM 157 Query: 131 AGLGYANPY 139 G+ NPY Sbjct: 158 RAAGFPNPY 166